DisplayUnityReport 45910 Ene24

January 2024
Conventional Units
Worldwide Report
Multiqual 1,2,3 • Lot 45910 • Exp 31−Mar−2024
Acetaminophen Chemiluminescence µg/mL

Level Mon Cum Level Mon Cum Level Mon Cum
Abbott ARCHITECT/Alinity (c, i, ci models)
Mean −− 13.91 −− −− −− 144.5
SD
CV
1 −−
−−
0.502
3.6
2 −−
−−
−−
−−
3 −−
−−
4.11
2.8
# Points −− 116 −− −− −− 123
# Labs 1 1
Beckman Coulter AU Series

Mean −− 14.11 −− 47.27 −− 144.2
SD
CV
1 −−
−−
0.811
5.8
2 −−
−−
1.01
2.1
3 −−
−−
10.42
7.2
# Points −− 1763 −− 11 −− 1728
# Labs 4 1 4
Siemens Dimension Series

Mean −− 22.70 −− −− −− 144.8
SD
CV
1 −−
−−
1.02
4.5
2 −−
−−
−−
−−
3 −−
−−
3.47
2.4
# Points −− 964 −− −− −− 951
# Labs 3 3
Method Group • Chemiluminescence

Mean −− 17.01 −− 47.27 −− 144.4
SD
CV
1 −−
−−
4.17
24.5
2 −−
−−
1.01
2.1
3 −−
−−
8.47
5.9
# Points −− 2843 −− 11 −− 2802
# Labs 8 1 8
Acetaminophen Colorimetric µg/mL

Siemens Atellica CH Analyzer
Mean −− 13.86 −− 44.93 −− −−
SD
CV
1 −−
−−
0.677
4.9
2 −−
−−
1.18
2.6
3 −−
−−
−−
−−
# Points −− 176 −− 175 −− −−
# Labs 1 1

Mean −− 22.31 −− 47.97 −− 143.7
SD
CV
1 −−
−−
1.01
4.5
2 −−
−−
1.08
2.2
3 −−
−−
1.78
1.2
# Points −− 459 −− 450 −− 452
# Labs 2 2 2
VITROS Microslide Series • Slide generation #17

Mean −− 16.29 −− 51.85 −− 145.7
SD
CV
1 −−
−−
0.416
2.6
2 −−
−−
0.550
1.1
3 −−
−−
2.34
1.6
# Points −− 818 −− 4 −− 780
# Labs 3 1 3
Method Group • Colorimetric

Mean −− 17.90 −− 47.15 −− 145.0
SD
CV
1 −−
−−
3.17
17.7
2 −−
−−
1.79
3.8
3 −−
−−
2.34
1.6
# Points −− 1453 −− 629 −− 1232
# Labs 6 4 5
The statistics in this report are derived from user−supplied data and are provided by Bio−Rad Laboratories as a service to its customers. Such action does not imply support of reported analytes and test methods. Refer to the package
insert for specific analyte claims and stability information. Qualitative percentages may not add up to 100 due to rounding. Peer group statistics contained in this report may not be used without the expressed written consent of Bio−Rad
Laboratories.
Copyright © 2017 Bio−Rad Laboratories, Inc. Generated 28−Feb−2024 22:18:49 Page 1

Worldwide Report January 2024
Multiqual 1,2,3 • Lot 45910 • Exp 31−Mar−2024 Conventional Units
Acetaminophen EIA µg/mL

Mean 14.13 14.05 45.40 45.51 144.7 144.9
SD
CV
1 0.704
5.0
0.759
5.4
2 2.08
4.6
2.23
4.9
3 9.34
6.5
10.31
7.1
# Points 222 11188 130 4653 193 11119
# Labs 7 28 4 11 6 28
Beckman Coulter AU Series • Emit tox Acetaminophen REF OSR7A229

Mean 14.40 19.01 −− 46.73 145.3 215.3
SD
CV
1 0.609
4.2
19.10
100.4
2
−−
−−
2.71
5.8
3 7.90
5.4
222.6
103.4
# Points 96 5833 −− 442 95 6077
# Labs 3 21 3 3 21
Roche cobas 6000/8000/c 311

Mean 13.73 13.88 42.94 44.16 133.7 136.2
SD
CV
1 0.771
5.6
0.942
6.8
2 1.25
2.9
1.53
3.5
3 9.87
7.4
9.83
7.2
# Points 128 4048 64 1966 131 4234
# Labs 3 12 2 6 3 12
Roche cobas c 303/503

Mean −− 14.32 −− 47.32 −− 138.8
SD
CV
1 −−
−−
0.490
3.4
2 −−
−−
1.47
3.1
3 −−
−−
7.22
5.2
# Points −− 1084 −− 1102 −− 1139
# Labs 2 2 2
Roche cobas c 303/503 • Roche ACET2, REF 08056684

Mean −− 14.09 −− −− −− 134.9
SD
CV
1 −−
−−
0.549
3.9
2 −−
−−
−−
−−
3 −−
−−
9.04
6.7
# Points −− 951 −− −− −− 958
# Labs 5 5
Method Group • EIA

Mean 14.07 15.29 44.59 45.49 141.4 160.8
SD
CV
1 0.744
5.3
9.86
64.5
2 2.18
4.9
2.25
4.9
3 10.57
7.5
118.0
73.3
# Points 446 23104 194 8163 419 23527
# Labs 13 68 6 22 12 68
Acetaminophen Enzymatic µg/mL

Beckman Coulter AU Series • Emit tox Acetaminophen REF OSR7A229
Mean −− 14.45 −− −− −− 148.1
SD
CV
1 −−
−−
0.590
4.1
2
−−
−−
−−
−−
3 −−
−−
8.25
5.6
# Points −− 370 −− −− −− 373
# Labs 2 2

Mean −− 13.92 −− −− −− 141.0
SD
CV
1 −−
−−
0.404
2.9
2 −−
−−
−−
−−
3 −−
−−
5.28
3.7
# Points −− 196 −− −− −− 176
# Labs 2 2
Siemens ADVIA Chemistry Systems

Mean 13.96 12.31 −− 44.59 143.9 140.3
SD
CV
1 0.326
2.3
1.25
10.1
2 −−
−−
1.25
2.8
3 2.43
1.7
2.79
2.0
# Points 65 6921 −− 5269 66 6342
# Labs 2 8 6 2 6
Siemens ADVIA Chemistry Systems • Siemens ADVIA Acetaminophen, Cal Lots pre 9520521
Mean −− 14.81 −− −− −− 138.4
SD
CV
1 −−
−−
0.809
5.5
−−
−−
2 −−
−−
3 −−
−−
6.54
4.7
# Points −− 541 −− −− −− 527
# Labs 1 1

Acetaminophen Enzymatic µg/mL

Mean −− 13.81 −− 44.96 −− 138.5
SD
CV
1 −−
−−
0.713
5.2
2 −−
−−
1.18
2.6
3 −−
−−
3.01
2.2
# Points −− 653 −− 664 −− 650
# Labs 2 2 2

Mean −− 15.60 −− 51.20 −− 141.2
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
0.000
0.0
3 −−
−−
0.000
0.0
# Points −− 1 −− 1 −− 1
# Labs 1 1 1

Mean −− 16.42 −− 53.34 −− 146.4
SD
CV
1 −−
−−
0.327
2.0
2 −−
−−
0.786
1.5
3 −−
−−
2.50
1.7
# Points −− 184 −− 184 −− 185
# Labs 3 3 3
Method Group • Enzymatic

Mean 13.96 12.78 −− 44.89 143.9 140.6
SD
CV
1 0.326
2.3
1.50
11.7
2 −−
−−
1.94
4.3
3 2.43
1.7
4.16
3.0
# Points 65 8866 −− 6118 66 8254
# Labs 2 19 12 2 17
Acetaminophen Enzymatic, colorimetric µg/mL

Mean 13.95 14.07 46.73 46.69 −− 147.5
SD
CV
1 1.92
13.7
0.415
2.9
2 1.53
3.3
1.16
2.5
3 −−
−−
2.42
1.6
# Points 2 907 2 638 −− 979
# Labs 1 12 1 9 11
Abbott ARCHITECT/Alinity (c, i, ci models) • Sekisui Diagnostics SEKURE

Mean 14.55 14.18 −− 47.40 149.7 149.0
SD
CV
1 0.522
3.6
0.468
3.3
2−−
−−
1.22
2.6
3 1.35
0.9
2.73
1.8
# Points 11 3634 −− 509 11 3336
# Labs 1 17 8 1 15
Roche cobas 6000/8000/c 311 • Roche Acetaminophen, No Correction

Mean 14.57 13.90 −− −− 144.3 140.5
SD
CV
1 0.960
6.6
0.858
6.2
−−
−−
2 −−
−−
3 12.46
8.6
8.57
6.1
# Points 242 1269 −− −− 241 1184
# Labs 1 3 1 3

Mean −− 13.65 −− 44.86 −− 138.1
SD
CV
1 −−
−−
0.645
4.7
2 −−
−−
1.21
2.7
3 −−
−−
3.10
2.2
# Points −− 11150 −− 3169 −− 10714
# Labs 12 4 11

Mean 22.80 22.93 47.97 48.72 142.3 144.3
SD
CV
1 1.00
4.4
1.10
4.8
2 0.901
1.9
1.35
2.8
3 2.94
2.1
2.78
1.9
# Points 363 16409 31 1658 361 18203
# Labs 14 52 1 7 14 47
Siemens Dimension Vista

Mean 23.49 23.36 49.47 49.98 149.5 147.6
SD
CV
1 1.03
4.4
1.11
4.7
2 0.814
1.6
1.29
2.6
3 3.68
2.5
2.83
1.9
# Points 372 58510 10 10519 288 54854
# Labs 13 150 2 27 13 148

Acetaminophen Enzymatic, colorimetric µg/mL

Mean −− 16.75 −− −− −− 142.6
SD
CV
1 −−
−−
0.329
2.0
2 −−
−−
−−
−−
3 −−
−−
2.47
1.7
# Points −− 1364 −− −− −− 1347
# Labs 2 2

Mean −− 16.61 −− −− −− 144.3
SD
CV
1 −−
−−
0.235
1.4
2 −−
−−
−−
−−
3 −−
−−
1.81
1.3
# Points −− 193 −− −− −− 189
# Labs 1 1

Mean 16.30 16.24 52.77 52.95 144.5 145.2
SD
CV
1 0.377
2.3
0.422
2.6
2 0.845
1.6
0.939
1.8
3 2.98
2.1
2.96
2.0
# Points 360 13379 130 4983 315 10910
# Labs 15 45 7 18 12 38
Method Group • Enzymatic, colorimetric

Mean 19.70 20.79 51.65 49.66 145.0 145.6
SD
CV
1 3.92
19.9
3.98
19.2
2 2.16
4.2
2.81
5.6
3 6.80
4.7
4.25
2.9
# Points 1350 107K 173 21477 1216 102K
# Labs 45 296 11 73 41 278
Acetaminophen GC−MS µg/mL

Mean −− 16.46 −− −− −− 145.0
SD
CV
1 −−
−−
0.186
1.1
2 −−
−−
−−
−−
3 −−
−−
1.41
1.0
# Points −− 863 −− −− −− 851
# Labs 2 2
Method Group • GC−MS

Mean −− 16.46 −− −− −− 145.0
SD
CV
1 −−
−−
0.186
1.1
2 −−
−−
−−
−−
3 −−
−−
1.41
1.0
# Points −− 863 −− −− −− 851
# Labs 2 2
Acetaminophen Immunoturbidimetric µg/mL

Mean −− 14.19 −− 46.23 −− 144.4
SD
CV
1 −−
−−
0.768
5.4
2 −−
−−
1.82
3.9
3 −−
−−
10.06
7.0
# Points −− 1858 −− 1273 −− 1862
# Labs 4 2 4
Beckman Coulter UniCel DxC Series

Mean 15.72 17.99 −− 56.89 172.1 174.3
SD
CV
1 1.75
11.2
1.62
9.0
2 −−
−−
2.60
4.6
3 6.98
4.1
7.70
4.4
# Points 77 5330 −− 427 68 5318
# Labs 2 17 3 2 17
Method Group • Immunoturbidimetric

Mean 15.72 17.01 −− 48.91 172.1 166.6
SD
CV
1 1.75
11.2
2.21
13.0
2 −−
−−
5.05
10.3
3 6.98
4.1
15.50
9.3
# Points 77 7188 −− 1700 68 7177
# Labs 2 21 5 2 21

Acid Phosphatase, Prostatic (Temperature Dependent) a−naphthyl phosphate, tartrate U/L @ 37° C
Mean −− 32.70 −− −− −− 231.9
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− 1 −− −− −− 1
# Labs 1 1
Method Group • a−naphthyl phosphate, tartrate

Mean −− 32.70 −− −− −− 231.9
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− 1 −− −− −− 1
# Labs 1 1
Acid Phosphatase, Total a−naphthyl phosphate, end point U/L @ 37° C

Mean 7.28 7.27 18.27 18.18 −− −−
SD
CV
1 0.271
3.7
0.406
5.6
2 0.421
2.3
0.465
2.6
3 −−
−−
−−
−−
# Points 31 116 31 118 −− −−
# Labs 1 1 1 1
Method Group • a−naphthyl phosphate, end point

Mean 7.28 7.27 18.27 18.18 −− −−
SD
CV
1 0.271
3.7
0.406
5.6
2 0.421
2.3
0.465
2.6
3 −−
−−
−−
−−
# Points 31 116 31 118 −− −−
# Labs 1 1 1 1
Acid Phosphatase, Total a−naphthyl phosphate, kinetic U/L @ 37° C

Mean 7.20 6.86 17.90 17.13 −− −−
SD
CV
1 0.000
0.0
0.207
3.0
2 0.000
0.0
0.525
3.1
3 −−
−−
−−
−−
# Points 1 7 1 7 −− −−
# Labs 1 1 1 1

Mean −− 7.52 −− −− −− 37.64
SD
CV
1 −−
−−
0.175
2.3
2 −−
−−
−−
−−
3 −−
−−
0.904
2.4
# Points −− 326 −− −− −− 326
# Labs 1 1
Spectronic Genesys • Biosystems S.A.

Mean −− 8.47 −− −− −− 41.55
SD
CV
1 −−
−−
0.472
5.6
2 −−
−−
−−
−−
3 −−
−−
1.68
4.0
# Points −− 125 −− −− −− 125
# Labs 1 1
Method Group • a−naphthyl phosphate, kinetic

Mean 7.20 7.77 17.90 17.13 −− 38.73
SD
CV
1 0.000
0.0
0.523
6.7
2 0.000
0.0
0.525
3.1
3 −−
−−
2.10
5.4
# Points 1 458 1 7 −− 451
# Labs 1 3 1 1 2
Albumin Agarose Gel %

Interlab G26
Mean −− 66.07 −− 62.63 −− 58.05
SD
CV
1 −−
−−
2.19
3.3
2 −−
−−
1.62
2.6
3 −−
−−
3.47
6.0
# Points −− 4 −− 4 −− 4
# Labs 1 1 1

Albumin Agarose Gel %

Method Group • Agarose Gel
Mean −− 66.07 −− 62.63 −− 58.05
SD
CV
1 −−
−−
2.19
3.3
2 −−
−−
1.62
2.6
3 −−
−−
3.47
6.0
# Points −− 4 −− 4 −− 4
# Labs 1 1 1
Albumin Bromcresol Green (BCG) %

Mean −− 2.58 −− −− −− 4.39
SD
CV
1 −−
−−
0.049
1.9
2 −−
−−
−−
−−
3 −−
−−
0.067
1.5
# Points −− 101 −− −− −− 101
# Labs 1 1
Method Group • Bromcresol Green (BCG)

Mean −− 2.58 −− −− −− 4.39
SD
CV
1 −−
−−
0.049
1.9
2 −−
−−
−−
−−
3 −−
−−
0.067
1.5
# Points −− 101 −− −− −− 101
# Labs 1 1
Albumin Bromcresol Green (BCG) g/dL @ 37° C

Mean −− 2.50 −− −− −− 4.21
SD
CV
1 −−
−−
0.066
2.6
2 −−
−−
−−
−−
3 −−
−−
0.087
2.1
# Points −− 99 −− −− −− 87
# Labs 1 1

Mean −− 2.50 −− −− −− 4.21
SD
CV
1 −−
−−
0.066
2.6
2 −−
−−
−−
−−
3 −−
−−
0.087
2.1
# Points −− 99 −− −− −− 87
# Labs 1 1
Albumin Bromcresol Green (BCG) g/dL

Mean 2.46 2.45 3.43 3.39 4.28 4.26
SD
CV
1 0.060
2.4
0.062
2.5
2 0.052
1.5
0.065
1.9
3 0.063
1.5
0.079
1.8
# Points 676 39242 281 19390 662 39895
# Labs 25 114 16 64 26 117
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH AlbBCG2, REF 04T34

Mean 2.50 2.50 3.46 3.45 −− 4.36
SD
CV
1 0.050
2.0
0.055
2.2
2
0.077
2.2
0.181
5.3
3 −−
−−
0.087
2.0
# Points 224 2457 224 1788 −− 1078
# Labs 10 17 10 15 4
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH AlbBCP2, REF 04U45

Mean −− 2.32 −− 3.19 −− −−
SD
CV
1 −−
−−
0.023
1.0
2 −−
−−
0.029
0.9
3 −−
−−
−−
−−
# Points −− 50 −− 50 −− −−
# Labs 2 2
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH Albumin BCG, REF 7D53
Mean 2.48 2.47 3.41 3.40 4.29 4.27
SD
CV
1 0.043
1.7
0.059
2.4
2
0.029
0.9
0.058
1.7
3 0.047
1.1
0.070
1.6
# Points 22 3511 22 2978 22 3372
# Labs 1 10 1 8 1 9


Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c AlbBCG2, REF 04U30
Mean 2.47 2.46 3.42 3.40 4.32 4.33
SD
CV
1 0.079
3.2
0.074
3.0
2
0.101
3.0
0.112
3.3
3 0.105
2.4
0.103
2.4
# Points 460 3034 325 1934 208 1527
# Labs 19 25 16 21 9 11
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c AlbBCP2, REF 04T82

Mean 2.46 2.47 3.44 3.42 −− −−
SD
CV
1 0.021
0.9
0.026
1.1
2
0.064
1.9
0.046
1.3
3 −−
−−
−−
−−
# Points 2 27 2 27 −− −−
# Labs 1 1 1 1
Abbott ARCHITECT/Alinity (c, i, ci models) • Sekisui Clinimate

Mean −− 2.41 −− 3.28 −− 4.16
SD
CV
1 −−
−−
0.035
1.5
2 −−
−−
0.039
1.2
3 −−
−−
0.057
1.4
# Points −− 265 −− 265 −− 265
# Labs 1 1 1
Abbott ARCHITECT/Alinity (c, i, ci models) • Zhong Sheng

Mean 2.50 2.48 3.42 3.49 4.27 4.28
SD
CV
1 0.019
0.8
0.023
0.9
0.023
0.7
2 0.143
4.1
3 0.025
0.6
0.089
2.1
# Points 91 1599 84 2032 87 2184
# Labs 2 2 2 4 2 4

Mean 2.50 2.47 3.42 3.37 4.27 4.22
SD
CV
1 0.066
2.6
0.071
2.9
2 0.083
2.4
0.087
2.6
3 0.095
2.2
0.106
2.5
# Points 2196 111K 1828 85634 1265 115K
# Labs 76 319 61 245 44 311
Beckman Coulter AU Series • BC AU Calibrator 66300

Mean −− 2.42 −− 3.38 −− 4.20
SD
CV
1 −−
−−
0.045
1.9
2 −−
−−
0.095
2.8
3 −−
−−
0.069
1.7
# Points −− 674 −− 912 −− 673
# Labs 6 8 6
Beckman Coulter AU Series • Beckman

Mean −− 2.45 −− −− −− 4.19
SD
CV
1 −−
−−
0.050
2.0
2 −−
−−
−−
−−
3 −−
−−
0.072
1.7
# Points −− 218 −− −− −− 197
# Labs 1 1
Beckman Coulter AU Series • Beckman Coulter AU US Calibrator DR0070

Mean −− 2.52 3.44 3.44 −− −−
SD
CV
1 −−
−−
0.050
2.0
0.070
2.0
2
0.072
2.1
3 −−
−−
−−
−−
# Points −− 209 61 322 −− −−
# Labs 2 2 2
Beckman Coulter AU Series • Fosun Diagnostics

Mean −− 2.59 −− 3.52 −− 4.37
SD
CV
1 −−
−−
0.090
3.5
2 −−
−−
0.104
2.9
3 −−
−−
0.134
3.1
# Points −− 231 −− 231 −− 229
# Labs 1 1 1
Beckman Coulter AU Series • LEADMAN

Mean 2.54 2.55 3.50 3.50 4.40 4.39
SD
CV
1 0.047
1.9
0.057
2.2
2 0.078
2.2
0.076
2.2
3 0.096
2.2
0.095
2.2
# Points 64 655 64 680 64 682
# Labs 2 2 2 2 2 2


Beckman Coulter AU Series • Maccura
Mean −− −− −− 3.36 −− 4.17
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.101
3.0
3 −−
−−
0.117
2.8
# Points −− −− −− 1106 −− 1121
# Labs 2 2
Beckman Coulter AU Series • Zhong Sheng

Mean −− −− 3.50 3.54 4.34 4.30
SD
CV
1 −−
−−
−−
−−
2 0.015
0.4
0.092
2.6
3 0.030
0.7
0.101
2.3
# Points −− −− 5 724 4 724
# Labs 1 2 1 2
Canon Medical Systems (Toshiba) TBA Series

Mean −− −− −− 3.60 −− 4.38
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.070
1.9
3 −−
−−
0.073
1.7
# Points −− −− −− 171 −− 172
# Labs 1 1
Dirui CS Series
Mean −− 2.56 −− 3.45 −− 4.25
SD
CV
1 −−
−−
0.053
2.1
2 −−
−−
0.052
1.5
3 −−
−−
0.074
1.8
# Points −− 770 −− 766 −− 768
# Labs 2 2 2
Dirui CS Series • Zhong Sheng

Mean −− −− 3.52 3.56 4.38 4.37
SD
CV
1 −−
−−
−−
−−
2 0.072
2.0
0.126
3.5
3 0.095
2.2
0.153
3.5
# Points −− −− 43 234 41 235
# Labs 3 3 3 3
ELITech Selectra Series

Mean 1.63 1.93 1.83 2.69 4.30 4.23
SD
CV
1 1.22
74.9
1.10
56.6
2 1.65
90.1
1.39
51.6
3 0.084
2.0
0.592
14.0
# Points 54 713 22 516 5 44
# Labs 3 4 2 4 1 2
ERBA XL−640
Mean −− 0.267 −− 0.353 −− −−
SD
CV
1 −−
−−
0.002
0.7
2 −−
−−
0.003
0.8
3 −−
−−
−−
−−
# Points −− 58 −− 58 −− −−
# Labs 1 1
Fuji Dri−Chem Series

Mean −− 2.72 −− 3.92 −− −−
SD
CV
1 −−
−−
0.122
4.5
2 −−
−−
0.104
2.6
3 −−
−−
−−
−−
# Points −− 24 −− 41 −− −−
# Labs 1 1
Fuji Dri−Chem Series • Fuji Dri−Chem ALB−P, REF 9903010

Mean −− 2.87 −− 4.08 −− −−
SD
CV
1 −−
−−
0.087
3.0
2 −−
−−
0.117
2.9
3 −−
−−
−−
−−
# Points −− 16 −− 16 −− −−
# Labs 2 2
Hitachi Chemistry Series

Mean −− 2.53 −− 3.48 −− 4.30
SD
CV
1 −−
−−
0.071
2.8
2 −−
−−
0.088
2.5
3 −−
−−
0.107
2.5
# Points −− 4547 −− 2899 −− 4651
# Labs 12 8 13


Hitachi Chemistry Series • Alternate Formulation/Standardization
Mean −− −− −− 3.61 −− 4.37
SD
CV
1 −−
−−
−−
−−
−−
−−
2 0.035
1.0
3 −−
−−
0.035
0.8
# Points −− −− −− 105 −− 105
# Labs 1 1
Hitachi Chemistry Series • Maccura

Mean −− 2.53 −− −− −− 4.34
SD
CV
1 −−
−−
0.042
1.7
2 −−
−−
−−
−−
3 −−
−−
0.080
1.9
# Points −− 89 −− −− −− 91
# Labs 1 1
Horiba ABX Pentra C400

Mean −− 2.52 −− 3.08 −− 4.19
SD
CV
1 −−
−−
0.105
4.2
2 −−
−−
0.230
7.5
3 −−
−−
0.173
4.1
# Points −− 38 −− 3 −− 39
# Labs 2 1 2
ILab Series
Mean 2.40 2.47 3.29 3.34 −− −−
SD
CV
1 0.063
2.6
0.103
4.2
2 0.030
0.9
0.111
3.3
3 −−
−−
−−
−−
# Points 11 48 11 48 −− −−
# Labs 1 1 1 1
Mindray BS Series
Mean 2.59 2.55 3.52 3.46 4.33 4.27
SD
CV
1 0.061
2.4
0.068
2.7
2 0.048
1.4
0.100
2.9
3 0.056
1.3
0.109
2.6
# Points 21 459 21 482 21 481
# Labs 1 3 1 2 1 2
Mindray BS Series • MINDRAY

Mean −− −− −− 3.36 −− 4.16
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.038
1.1
3 −−
−−
0.047
1.1
# Points −− −− −− 148 −− 148
# Labs 1 1
Mindray CL Series
Mean −− −− −− 3.43 −− 4.27
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.034
1.0
3 −−
−−
0.051
1.2
# Points −− −− −− 86 −− 87
# Labs 1 1
Mindray CL Series • Zhong Sheng

Mean −− −− −− 3.57 −− 4.18
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.060
1.7
3 −−
−−
0.074
1.8
# Points −− −− −− 276 −− 277
# Labs 2 2
RANDOX RX daytona
Mean 2.87 2.79 3.72 3.64 4.54 4.54
SD
CV
1 0.159
5.5
0.156
5.6
2 0.084
2.3
0.187
5.1
3 0.000
0.0
0.000
0.0
# Points 20 175 16 164 1 1
# Labs 1 1 1 1 1 1
RANDOX RX imola
Mean 2.59 2.58 3.48 3.46 −− −−
SD
CV
1 0.016
0.6
0.020
0.8
2 0.025
0.7
0.027
0.8
3 −−
−−
−−
−−
# Points 26 227 24 196 −− −−
# Labs 1 1 1 1


Mean 2.61 2.58 3.55 3.58 4.45 4.49
SD
CV
1 0.103
4.0
0.096
3.7
2 0.094
2.7
0.099
2.8
3 0.096
2.1
0.114
2.5
# Points 3100 79340 401 27589 3119 85705
# Labs 53 157 11 76 51 172
Roche cobas 6000/8000/c 311 • 2nd Generation

Mean −− 2.72 −− −− −− 4.65
SD
CV
1 −−
−−
0.154
5.7
2 −−
−−
−−
−−
3 −−
−−
0.151
3.2
# Points −− 675 −− −− −− 676
# Labs 2 2

Mean 2.63 2.62 3.62 3.63 4.49 4.53
SD
CV
1 0.066
2.5
0.072
2.7
2 0.090
2.5
0.084
2.3
3 0.079
1.8
0.099
2.2
# Points 154 6302 107 5145 100 5870
# Labs 5 16 3 11 4 15
Roche cobas c 303/503 • Roche ALB2, REF 08056692

Mean 2.68 2.61 3.73 3.61 4.44 4.48
SD
CV
1 0.098
3.7
0.097
3.7
2 0.094
2.5
0.105
2.9
3 0.122
2.8
0.136
3.0
# Points 129 7825 27 1254 99 7650
# Labs 4 28 1 5 3 26
Roche cobas c 303/503 • Roche ALBT2, REF 08056722

Mean −− 2.73 −− −− −− 4.59
SD
CV
1 −−
−−
0.082
3.0
2 −−
−−
−−
−−
3 −−
−−
0.059
1.3
# Points −− 12 −− −− −− 13
# Labs 1 1

Mean 2.60 2.59 3.58 3.59 4.53 4.57
SD
CV
1 0.079
3.0
0.099
3.8
2 0.064
1.8
0.102
2.9
3 0.078
1.7
0.092
2.0
# Points 153 1812 154 2071 64 1044
# Labs 3 4 3 4 2 4
Roche cobas Integra / c 111

Mean 2.62 2.56 3.60 3.52 4.32 4.38
SD
CV
1 0.082
3.1
0.082
3.2
2 0.100
2.8
0.103
2.9
3 0.087
2.0
0.107
2.4
# Points 99 3757 34 816 99 3776
# Labs 3 12 1 2 3 12
Roche cobas Integra / c 111 • 2nd Generation

Mean −− 2.64 −− −− −− 4.52
SD
CV
1 −−
−−
0.099
3.7
2 −−
−−
−−
−−
3 −−
−−
0.161
3.5
# Points −− 122 −− −− −− 125
# Labs 1 1
Roche Hitachi Systems (International)

Mean 2.55 2.68 3.51 3.58 4.41 4.41
SD
CV
1 0.030
1.2
0.130
4.9
2 0.039
1.1
0.140
3.9
3 0.027
0.6
0.155
3.5
# Points 31 953 31 1184 31 1059
# Labs 1 4 1 5 1 4
Roche Hitachi Systems (International) • Wako

Mean −− 2.56 −− 3.51 −− 4.43
SD
CV
1 −−
−−
0.038
1.5
2 −−
−−
0.049
1.4
3 −−
−−
0.067
1.5
# Points −− 629 −− 630 −− 630
# Labs 2 2 2


Roche Hitachi/MODULAR
Mean −− 2.59 −− 3.52 −− 4.37
SD
CV
1 −−
−−
0.078
3.0
2 −−
−−
0.102
2.9
3 −−
−−
0.163
3.7
# Points −− 275 −− 608 −− 600
# Labs 1 4 2
Roche Hitachi/MODULAR • Sekisui Clinimate

Mean −− 2.47 −− −− −− 4.21
SD
CV
1 −−
−−
0.050
2.0
2 −−
−−
−−
−−
3 −−
−−
0.061
1.5
# Points −− 278 −− −− −− 278
# Labs 1 1
Shanghai Kehua Bio−engineering (KHB)

Mean −− −− −− 3.52 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.066
1.9
3 −−
−−
−−
−−
# Points −− −− −− 25 −− −−
# Labs 1

Mean 2.43 2.52 3.49 3.49 4.23 4.38
SD
CV
1 0.101
4.2
0.074
2.9
2 0.112
3.2
0.092
2.6
3 0.100
2.4
0.096
2.2
# Points 141 8427 138 4642 113 9341
# Labs 5 27 5 23 4 27

Mean 2.52 2.54 3.48 3.48 4.32 4.37
SD
CV
1 0.072
2.9
0.059
2.3
2 0.074
2.1
0.082
2.3
3 0.089
2.1
0.107
2.4
# Points 128 49868 78 13268 141 15282
# Labs 6 59 5 47 7 48

Mean −− 2.34 −− 3.25 −− −−
SD
CV
1 −−
−−
0.059
2.5
2 −−
−−
0.058
1.8
3 −−
−−
−−
−−
# Points −− 350 −− 351 −− −−
# Labs 1 1
Thermo Konelab 20/30/60i • Wiener lab

Mean −− −− 0.003 0.003 −− −−
SD
CV
1 −−
−−
−−
−−
2 0.000
2.4
0.000
2.2
3 −−
−−
−−
−−
# Points −− −− 21 28 −− −−
# Labs 1 1
Tokyo Boeki 24i (BIOLIS/Prestige/Sirrus/MGC)

Mean −− 2.95 −− 3.82 −− 4.54
SD
CV
1 −−
−−
0.083
2.8
2 −−
−−
0.105
2.7
3 −−
−−
0.143
3.2
# Points −− 107 −− 107 −− 107
# Labs 1 1 1
Toshiba−TBA
Mean 2.50 2.59 −− −− 4.50 4.39
SD
CV
1 0.000
0.0
0.031
1.2
2 −−
−−
−−
−−
3 0.000
0.0
0.115
2.6
# Points 2 362 −− −− 1 439
# Labs 1 1 1 2

Mean −− 2.29 −− 3.20 −− 4.23
SD
CV
1 −−
−−
0.055
2.4
2 −−
−−
0.077
2.4
3 −−
−−
0.113
2.7
# Points −− 233 −− 236 −− 231
# Labs 1 1 1


Mean −− 2.28 −− 3.27 −− 4.14
SD
CV
1 −−
−−
0.050
2.2
2 −−
−−
0.089
2.7
3 −−
−−
0.081
2.0
# Points −− 273 −− 271 −− 265
# Labs 2 2 2

Mean −− 2.26 −− 3.23 −− 4.08
SD
CV
1 −−
−−
0.050
2.2
2 −−
−−
0.053
1.6
3 −−
−−
0.069
1.7
# Points −− 182 −− 182 −− 180
# Labs 2 2 2

Mean −− 2.37 −− 3.35 −− 4.31
SD
CV
1 −−
−−
0.057
2.4
2 −−
−−
0.045
1.4
3 −−
−−
0.104
2.4
# Points −− 647 −− 347 −− 744
# Labs 3 2 3

Mean 2.28 2.29 3.34 3.32 4.28 4.20
SD
CV
1 0.048
2.1
0.035
1.5
2 0.052
1.5
0.055
1.7
3 0.067
1.6
0.088
2.1
# Points 122 636 66 579 126 643
# Labs 3 3 2 2 3 3

Mean −− 2.23 −− −− −− 4.19
SD
CV
1 −−
−−
0.112
5.0
2 −−
−−
−−
−−
3 −−
−−
0.172
4.1
# Points −− 246 −− −− −− 235
# Labs 2 2

Mean −− 2.30 −− 3.40 −− −−
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
0.000
0.0
3 −−
−−
−−
−−
# Points −− 2 −− 2 −− −−
# Labs 1 1

Mean −− 2.45 −− 3.39 −− −−
SD
CV
1 −−
−−
0.082
3.3
2 −−
−−
0.111
3.3
3 −−
−−
−−
−−
# Points −− 160 −− 160 −− −−
# Labs 1 1

Mean 2.54 2.52 3.43 3.43 4.37 4.33
SD
CV
1 0.167
6.6
0.116
4.6
2 0.316
9.2
0.167
4.9
3 0.126
2.9
0.163
3.8
# Points 7926 334K 4090 184K 6273 309K
# Labs 227 867 154 604 170 835
Albumin Bromcresol Green (BCG) − Vitros g/dL

Hitachi Chemistry Series • Sekisui Clinimate
Mean −− 2.44 −− −− −− 4.19
SD
CV
1 −−
−−
0.052
2.1
2 −−
−−
−−
−−
3 −−
−−
0.066
1.6
# Points −− 389 −− −− −− 388
# Labs 2 2

Mean 2.33 2.28 4.02 3.75 4.19 4.09
SD
CV
1 0.136
5.8
0.085
3.7
2 0.597
14.9
0.550
14.7
3 0.068
1.6
0.236
5.8
# Points 64 1916 32 1061 51 1731
# Labs 3 17 3 10 2 10


Mean −− 2.14 −− −− −− 4.19
SD
CV
1 −−
−−
0.030
1.4
2 −−
−−
−−
−−
3 −−
−−
0.093
2.2
# Points −− 52 −− −− −− 53
# Labs 1 1

Mean −− 2.29 −− −− −− 4.20
SD
CV
1 −−
−−
0.028
1.2
2 −−
−−
−−
−−
3 −−
−−
0.056
1.3
# Points −− 57 −− −− −− 57
# Labs 1 1

Mean 2.25 2.20 3.24 3.24 −− 4.16
SD
CV
1 0.035
1.6
0.116
5.3
2 0.064
2.0
0.077
2.4
3 −−
−−
0.078
1.9
# Points 76 978 76 699 −− 346
# Labs 2 3 2 2 2

Mean −− 2.35 −− 3.35 −− 4.23
SD
CV
1 −−
−−
0.063
2.7
2 −−
−−
0.091
2.7
3 −−
−−
0.117
2.8
# Points −− 3505 −− 1655 −− 3486
# Labs 21 12 21

Mean −− 2.32 −− 3.30 −− 4.18
SD
CV
1 −−
−−
0.112
4.8
2 −−
−−
0.119
3.6
3 −−
−−
0.207
5.0
# Points −− 2528 −− 1384 −− 2530
# Labs 15 10 15

Mean −− 2.39 −− 3.39 −− 4.33
SD
CV
1 −−
−−
0.080
3.4
2 −−
−−
0.053
1.6
3 −−
−−
0.164
3.8
# Points −− 2239 −− 412 −− 2195
# Labs 13 6 11

Mean 2.34 2.33 3.48 3.37 4.28 4.23
SD
CV
1 0.066
2.8
0.097
4.2
2 0.081
2.3
0.104
3.1
3 0.168
3.9
0.191
4.5
# Points 233 3369 46 808 179 3148
# Labs 9 14 3 7 8 14

Mean 2.33 2.17 3.30 3.30 −− 3.85
SD
CV
1 0.062
2.7
0.144
6.6
2 0.041
1.2
0.041
1.2
3 −−
−−
0.125
3.2
# Points 23 60 20 20 −− 39
# Labs 1 2 1 1 1

Mean −− 2.15 −− 3.24 −− 4.19
SD
CV
1 −−
−−
0.028
1.3
2 −−
−−
0.095
2.9
3 −−
−−
0.122
2.9
# Points −− 66 −− 40 −− 111
# Labs 1 1 2

Mean −− 2.18 −− −− −− 4.26
SD
CV
1 −−
−−
0.041
1.9
2 −−
−−
−−
−−
3 −−
−−
0.080
1.9
# Points −− 87 −− −− −− 91
# Labs 1 1


Mean −− 2.18 −− 3.31 −− 4.12
SD
CV
1 −−
−−
0.077
3.5
2 −−
−−
0.073
2.2
3 −−
−−
0.131
3.2
# Points −− 699 −− 366 −− 1088
# Labs 4 2 5

Mean −− 2.24 −− 3.29 −− 4.14
SD
CV
1 −−
−−
0.077
3.4
2 −−
−−
0.104
3.2
3 −−
−−
0.158
3.8
# Points −− 6601 −− 1664 −− 6104
# Labs 42 12 41

Mean −− 2.22 −− 3.33 −− 4.15
SD
CV
1 −−
−−
0.078
3.5
2 −−
−−
0.110
3.3
3 −−
−−
0.130
3.1
# Points −− 2314 −− 494 −− 2260
# Labs 19 6 17

Mean 2.22 2.22 3.25 3.25 4.18 4.18
SD
CV
1 0.043
2.0
0.043
2.0
2 0.099
3.1
0.099
3.1
3 0.112
2.7
0.112
2.7
# Points 17 17 17 17 17 17
# Labs 1 1 1 1 1 1

Mean −− 2.27 −− 3.29 −− 4.18
SD
CV
1 −−
−−
0.066
2.9
2 −−
−−
0.098
3.0
3 −−
−−
0.134
3.2
# Points −− 4067 −− 2036 −− 4060
# Labs 38 19 36

Mean 2.31 2.29 −− 3.34 4.26 4.21
SD
CV
1 0.040
1.7
0.070
3.1
2 −−
−−
0.103
3.1
3 0.060
1.4
0.143
3.4
# Points 20 24923 −− 8143 18 24233
# Labs 1 125 38 1 120

Mean −− 2.34 −− 3.34 −− 4.12
SD
CV
1 −−
−−
0.061
2.6
2 −−
−−
0.051
1.5
3 −−
−−
0.105
2.6
# Points −− 75 −− 35 −− 75
# Labs 2 1 2

Mean 2.28 2.30 3.28 3.34 4.14 4.22
SD
CV
1 0.082
3.6
0.078
3.4
2 0.116
3.5
0.114
3.4
3 0.183
4.4
0.150
3.6
# Points 445 12392 223 5433 362 11415
# Labs 22 94 13 42 17 80

Mean 2.27 2.27 3.30 3.33 4.14 4.16
SD
CV
1 0.075
3.3
0.076
3.3
2 0.106
3.2
0.112
3.4
3 0.169
4.1
0.167
4.0
# Points 435 5821 145 3054 448 5246
# Labs 19 52 8 25 18 44

Mean 2.19 2.25 3.17 3.24 3.99 4.12
SD
CV
1 0.019
0.9
0.058
2.6
2 0.035
1.1
0.094
2.9
3 0.051
1.3
0.117
2.9
# Points 29 1882 29 617 5 1601
# Labs 2 24 2 11 1 19


Mean 2.25 2.28 3.27 3.33 4.13 4.18
SD
CV
1 0.063
2.8
0.068
3.0
2 0.098
3.0
0.098
2.9
3 0.110
2.7
0.134
3.2
# Points 319 1754 194 1175 228 1554
# Labs 13 17 8 10 9 12

Mean −− 2.34 −− −− −− 4.35
SD
CV
1 −−
−−
0.063
2.7
2 −−
−−
−−
−−
3 −−
−−
0.118
2.7
# Points −− 54 −− −− −− 54
# Labs 1 1

Mean −− −− −− −− −− 4.20
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− −− −− −− −− 1
# Labs 1

Mean −− 2.29 −− −− −− 4.12
SD
CV
1 −−
−−
0.033
1.5
2 −−
−−
−−
−−
3 −−
−−
0.075
1.8
# Points −− 124 −− −− −− 124
# Labs 2 2
VITROS Microwell Series

Mean −− 2.32 −− −− −− 4.16
SD
CV
1 −−
−−
0.042
1.8
2 −−
−−
−−
−−
3 −−
−−
0.128
3.1
# Points −− 107 −− −− −− 110
# Labs 1 1
Method Group • Bromcresol Green (BCG) − Vitros

Mean 2.28 2.29 3.32 3.34 4.16 4.19
SD
CV
1 0.081
3.5
0.083
3.6
2 0.218
6.6
0.169
5.1
3 0.168
4.0
0.155
3.7
# Points 1661 74244 782 29007 1308 70663
# Labs 73 507 41 216 57 457
Albumin Bromcresol Purple (BCP) %

Mean −− 2.32 −− 3.19 −− 3.99
SD
CV
1 −−
−−
0.055
2.4
2 −−
−−
0.051
1.6
3 −−
−−
0.033
0.8
# Points −− 126 −− 126 −− 126
# Labs 1 1 1
Method Group • Bromcresol Purple (BCP)

Mean −− 2.32 −− 3.19 −− 3.99
SD
CV
1 −−
−−
0.055
2.4
2 −−
−−
0.051
1.6
3 −−
−−
0.033
0.8
# Points −− 126 −− 126 −− 126
# Labs 1 1 1
Albumin Bromcresol Purple (BCP) g/dL

Abaxis Piccolo Xpress
Mean 2.80 2.76 3.60 3.59 −− 4.27
SD
CV
1 0.000
0.0
0.061
2.2
2 0.000
0.0
0.061
1.7
3 −−
−−
0.072
1.7
# Points 1 103 1 22 −− 78
# Labs 1 2 1 1 2


Mean 2.43 2.44 3.29 3.29 4.07 4.10
SD
CV
1 0.047
1.9
0.063
2.6
2 0.030
0.9
0.079
2.4
3 0.051
1.2
0.079
1.9
# Points 87 15896 31 7681 87 15941
# Labs 3 57 1 34 3 53
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH AlbBCG2, REF 04T34

Mean 2.50 2.50 3.46 3.47 −− −−
SD
CV
1 0.016
0.6
0.015
0.6
2
0.025
0.7
0.025
0.7
3 −−
−−
−−
−−
# Points 27 50 26 49 −− −−
# Labs 1 1 1 1
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH AlbBCP2, REF 04U45

Mean 2.36 2.36 3.24 3.24 4.23 4.21
SD
CV
1 0.047
2.0
0.058
2.4
2
0.056
1.7
0.077
2.4
3 0.894
21.1
0.829
19.7
# Points 329 1763 327 1684 7 8
# Labs 11 14 11 14 2 3
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c AlbBCP2, REF 04T82

Mean 2.36 2.37 3.22 3.16 4.07 4.08
SD
CV
1 0.039
1.6
0.078
3.3
2 0.045
1.4
0.081
2.5
3 0.045
1.1
0.050
1.2
# Points 82 543 46 236 34 305
# Labs 3 3 2 2 1 1

Mean −− 2.49 −− 3.41 −− 4.26
SD
CV
1 −−
−−
0.063
2.5
2 −−
−−
0.063
1.8
3 −−
−−
0.079
1.9
# Points −− 1425 −− 1380 −− 1387
# Labs 8 4 6

Mean 2.45 2.45 −− 3.41 4.17 4.22
SD
CV
1 0.071
2.9
0.065
2.7
2 −−
−−
0.101
3.0
3 0.078
1.9
0.103
2.4
# Points 63 10991 −− 2217 65 10168
# Labs 2 35 8 2 32

Mean −− 2.88 −− 4.09 −− −−
SD
CV
1 −−
−−
0.125
4.3
2 −−
−−
0.092
2.2
3 −−
−−
−−
−−
# Points −− 53 −− 51 −− −−
# Labs 1 1
Hitachi Chemistry Series • Sekisui Pureauto

Mean −− 2.47 −− −− −− −−
SD
CV
1 −−
−−
0.055
2.2
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 62 −− −− −− −−
# Labs 1

Mean −− 2.41 −− 3.27 −− 4.07
SD
CV
1 −−
−−
0.080
3.3
2 −−
−−
0.097
3.0
3 −−
−−
0.106
2.6
# Points −− 19673 −− 16642 −− 18527
# Labs 49 42 45
Roche cobas c 303/503 • Roche ALBP, REF 08056714

Mean 2.37 2.36 −− 3.24 4.14 4.03
SD
CV
1 0.030
1.3
0.058
2.5
2 −−
−−
0.052
1.6
3 0.047
1.1
0.087
2.2
# Points 192 5303 −− 2416 81 5258
# Labs 4 8 2 2 7


Mean −− 2.28 −− 3.17 −− 4.00
SD
CV
1 −−
−−
0.043
1.9
2 −−
−−
0.053
1.7
3 −−
−−
0.064
1.6
# Points −− 6817 −− 6774 −− 5772
# Labs 8 8 6

Mean 2.30 2.34 3.16 3.21 4.08 4.05
SD
CV
1 0.044
1.9
0.073
3.1
2 0.044
1.4
0.080
2.5
3 0.050
1.2
0.123
3.0
# Points 400 11335 338 4819 76 9248
# Labs 11 39 10 24 3 28

Mean 2.23 2.31 3.11 3.21 3.95 4.03
SD
CV
1 0.083
3.7
0.072
3.1
2 0.091
2.9
0.077
2.4
3 0.098
2.5
0.090
2.2
# Points 1644 97786 416 15866 1464 88668
# Labs 57 240 15 51 50 222

Mean 2.32 2.32 3.15 3.17 3.96 3.97
SD
CV
1 0.069
3.0
0.090
3.9
2 0.084
2.7
0.093
2.9
3 0.094
2.4
0.097
2.4
# Points 2896 223K 841 60686 2418 198K
# Labs 82 439 28 119 69 411
Toshiba−TBA • Beijing Strong Biotechnologies (BSBE)

Mean −− 2.71 −− 3.62 −− 4.42
SD
CV
1 −−
−−
0.036
1.3
2 −−
−−
0.049
1.4
3 −−
−−
0.062
1.4
# Points −− 450 −− 456 −− 480
# Labs 3 3 3
Method Group • Bromcresol Purple (BCP)

Mean 2.30 2.33 3.17 3.21 3.97 4.01
SD
CV
1 0.087
3.8
0.093
4.0
2 0.094
3.0
0.109
3.4
3 0.109
2.7
0.110
2.8
# Points 5721 395K 2026 121K 4232 354K
# Labs 175 908 69 316 132 820
Albumin Dipstick g/dL

Mean −− 2.74 −− −− −− 4.36
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− 1 −− −− −− 1
# Labs 1 1
Method Group • Dipstick

Mean −− 2.74 −− −− −− 4.36
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− 1 −− −− −− 1
# Labs 1 1
Albumin Immunonephelometric, fixed time, kinetic g/dL

Mean −− 2.37 −− 3.25 −− 4.08
SD
CV
1 −−
−−
0.061
2.6
2 −−
−−
0.074
2.3
3 −−
−−
0.090
2.2
# Points −− 591 −− 924 −− 510
# Labs 1 1 1

Albumin Immunonephelometric, fixed time, kinetic g/dL

Mean 2.54 2.44 −− 3.62 4.23 4.15
SD
CV
1 0.183
7.2
0.161
6.6
2 −−
−−
0.169
4.7
3 0.387
9.1
0.263
6.3
# Points 158 7628 −− 787 63 6782
# Labs 3 16 4 3 16
Method Group • Immunonephelometric, fixed time, kinetic

Mean 2.54 2.44 −− 3.42 4.23 4.15
SD
CV
1 0.183
7.2
0.157
6.4
2 −−
−−
0.224
6.6
3 0.387
9.1
0.255
6.2
# Points 158 8219 −− 1711 63 7292
# Labs 3 17 5 3 17
Albumin Immunoturbidimetric g/dL

Abbott ARCHITECT/Alinity (c, i, ci models) • DiAgam
Mean −− 2.43 −− 3.31 −− 4.15
SD
CV
1 −−
−−
0.059
2.4
2 −−
−−
0.081
2.5
3 −−
−−
0.097
2.3
# Points −− 2314 −− 2275 −− 2085
# Labs 4 4 3

Mean −− 2.54 −− 3.50 −− 4.41
SD
CV
1 −−
−−
0.093
3.7
2 −−
−−
0.127
3.6
3 −−
−−
0.134
3.0
# Points −− 2281 −− 2382 −− 2298
# Labs 5 5 5

Mean 2.44 2.46 3.32 3.35 4.18 4.21
SD
CV
1 0.067
2.7
0.051
2.1
2 0.067
2.0
0.061
1.8
3 0.078
1.9
0.083
2.0
# Points 45 531 47 542 48 571
# Labs 2 3 2 3 2 3
Roche cobas c 303/503 • Roche ALBP, REF 08056714

Mean −− 2.53 −− −− −− 4.46
SD
CV
1 −−
−−
0.134
5.3
2 −−
−−
−−
−−
3 −−
−−
0.156
3.5
# Points −− 2 −− −− −− 2
# Labs 1 1

Mean 0.002 0.002 0.003 0.003 0.004 0.004
SD
CV
1 0.000
5.2
0.000
3.4
2 0.000
3.4
0.000
2.6
3 0.000
3.0
0.000
2.6
# Points 62 184 62 184 62 184
# Labs 2 2 2 2 2 2

Mean −− 2.44 −− 3.32 −− 4.17
SD
CV
1 −−
−−
0.070
2.9
2 −−
−−
0.085
2.6
3 −−
−−
0.108
2.6
# Points −− 500 −− 530 −− 525
# Labs 1 1 1

Mean 1.03 2.40 1.43 3.29 1.83 4.13
SD
CV
1 1.21
117.7
0.443
18.4
2 1.65
115.2
0.603
18.4
3 2.08
113.9
0.773
18.7
# Points 107 5812 109 5913 110 5665
# Labs 4 16 4 15 4 15

Albumin REP Gel %

Helena REP
Mean −− −− −− 58.22 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
3.17
5.4
3 −−
−−
−−
−−
# Points −− −− −− 85 −− −−
# Labs 1
Method Group • REP Gel

Mean −− −− −− 58.22 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
3.17
5.4
3 −−
−−
−−
−−
# Points −− −− −− 85 −− −−
# Labs 1
Alkaline Phosphatase 4−aminoantipyrine U/L @ 25° C

Mean −− 24.31 −− −− −− 275.8
SD
CV
1 −−
−−
2.66
10.9
2 −−
−−
−−
−−
3 −−
−−
14.26
5.2
# Points −− 301 −− −− −− 301
# Labs 1 1
Method Group • 4−aminoantipyrine

Mean −− 24.31 −− −− −− 275.8
SD
CV
1 −−
−−
2.66
10.9
2 −−
−−
−−
−−
3 −−
−−
14.26
5.2
# Points −− 301 −− −− −− 301
# Labs 1 1
Alkaline Phosphatase 4−aminoantipyrine U/L @ 37° C

Mean −− 32.12 −− 150.7 −− 310.7
SD
CV
1 −−
−−
2.00
6.2
2 −−
−−
3.02
2.0
3 −−
−−
4.99
1.6
# Points −− 64 −− 60 −− 58
# Labs 2 2 2

Mean −− 34.24 −− 131.1 −− 229.9
SD
CV
1 −−
−−
1.79
5.2
2 −−
−−
4.02
3.1
3 −−
−−
6.41
2.8
# Points −− 97 −− 109 −− 109
# Labs 1 1 1

Mean −− 34.17 −− 130.8 −− 235.7
SD
CV
1 −−
−−
1.92
5.6
2 −−
−−
5.18
4.0
3 −−
−−
9.84
4.2
# Points −− 296 −− 295 −− 295
# Labs 1 1 1
Method Group • 4−aminoantipyrine

Mean −− 33.90 −− 133.5 −− 243.7
SD
CV
1 −−
−−
2.03
6.0
2 −−
−−
8.15
6.1
3 −−
−−
26.94
11.1
# Points −− 457 −− 464 −− 462
# Labs 4 4 4
Alkaline Phosphatase PNPP, AMP Buffer U/L @ 25° C

Mean −− 31.20 −− −− −− 303.2
SD
CV
1 −−
−−
2.49
8.0
2 −−
−−
−−
−−
3 −−
−−
8.81
2.9
# Points −− 305 −− −− −− 584
# Labs 4 4


Mean −− 24.66 −− 138.4 −− 298.1
SD
CV
1 −−
−−
1.66
6.7
2 −−
−−
4.42
3.2
3 −−
−−
9.66
3.2
# Points −− 207 −− 185 −− 185
# Labs 2 2 2

Mean −− 24.12 −− −− −− 297.5
SD
CV
1 −−
−−
1.76
7.3
2 −−
−−
−−
−−
3 −−
−−
9.22
3.1
# Points −− 710 −− −− −− 728
# Labs 2 2
ILab Series
Mean 28.00 29.02 160.8 158.7 −− −−
SD
CV
1 3.71
13.3
3.77
13.0
2 6.63
4.1
8.49
5.3
3 −−
−−
−−
−−
# Points 11 48 11 48 −− −−
# Labs 1 1 1 1

Mean −− 31.51 −− −− −− 272.1
SD
CV
1 −−
−−
2.00
6.4
2 −−
−−
−−
−−
3 −−
−−
6.44
2.4
# Points −− 1091 −− −− −− 1104
# Labs 2 2
Roche cobas c 303/503 • Roche ALP2, REF 08056757

Mean 27.48 30.50 −− −− 262.9 270.2
SD
CV
1 1.80
6.6
2.34
7.7
2 −−
−−
−−
−−
3 4.21
1.6
7.59
2.8
# Points 89 1834 −− −− 78 1823
# Labs 2 2 2 2

Mean −− 27.15 −− 132.0 −− −−
SD
CV
1 −−
−−
2.89
10.7
2 −−
−−
6.69
5.1
3 −−
−−
−−
−−
# Points −− 106 −− 56 −− −−
# Labs 1 1
Method Group • PNPP, AMP Buffer

Mean 27.54 28.64 160.8 140.5 262.9 283.5
SD
CV
1 2.08
7.5
3.65
12.7
2 6.63
4.1
10.24
7.3
3 4.21
1.6
17.02
6.0
# Points 100 3210 11 289 78 3320
# Labs 3 12 1 4 2 10

Mean −− 28.49 −− −− −− 293.0
SD
CV
1 −−
−−
2.31
8.1
2 −−
−−
−−
−−
3 −−
−−
6.93
2.4
# Points −− 467 −− −− −− 312
# Labs 1 1

Mean −− 28.49 −− −− −− 293.0
SD
CV
1 −−
−−
2.31
8.1
2 −−
−−
−−
−−
3 −−
−−
6.93
2.4
# Points −− 467 −− −− −− 312
# Labs 1 1


Mean 22.00 23.49 −− −− 284.0 287.7
SD
CV
1 2.00
9.1
1.94
8.3
2 −−
−−
−−
−−
3 10.00
3.5
8.49
2.9
# Points 22 403 −− −− 22 403
# Labs 1 1 1 1

Mean 22.00 23.49 −− −− 284.0 287.7
SD
CV
1 2.00
9.1
1.94
8.3
2 −−
−−
−−
−−
3 10.00
3.5
8.49
2.9
# Points 22 403 −− −− 22 403
# Labs 1 1 1 1

Mean −− 37.21 −− −− −− 319.2
SD
CV
1 −−
−−
4.16
11.2
2 −−
−−
−−
−−
3 −−
−−
10.28
3.2
# Points −− 75 −− −− −− 73
# Labs 1 1

Mean 28.05 29.52 138.5 142.3 287.7 295.5
SD
CV
1 2.84
10.1
2.55
8.6
2 7.50
5.4
7.31
5.1
3 11.70
4.1
11.26
3.8
# Points 957 54050 415 24140 824 52975
# Labs 30 160 16 86 26 141
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH Alk Phos REF 7D55
Mean 22.62 23.31 118.2 123.6 −− −−
SD
CV
1 2.06
9.1
2.73
11.7
2
8.03
6.8
9.74
7.9
3 −−
−−
−−
−−
# Points 13 169 13 169 −− −−
# Labs 1 1 1 1
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH AlkP2 REF 04S87

Mean 25.12 24.71 134.7 132.9 −− −−
SD
CV
1 3.32
13.2
3.24
13.1
2
7.95
5.9
8.73
6.6
3 −−
−−
−−
−−
# Points 29 39 29 39 −− −−
# Labs 2 2 2 2
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH AlkP2, REF 04S87 (Factored, IFCC Correlated)
Mean 26.97 27.61 137.4 138.2 −− 314.8
SD
CV
1 1.92
7.1
2.70
9.8
2
6.12
4.5
5.71
4.1
3 −−
−−
7.98
2.5
# Points 275 1469 273 1299 −− 165
# Labs 8 11 8 9 3
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c AlkP2, REF 04T83 (Factored, IFCC Correlated)
Mean 28.58 29.04 140.7 141.2 308.1 301.4
SD
CV
1 1.72
6.0
2.41
8.3
25.65
4.0
7.50
5.3
3 5.07
1.6
16.16
5.4
# Points 155 1818 138 1256 17 1003
# Labs 6 10 6 8 1 4
Abbott ARCHITECT/Alinity (c, i, ci models) • Factored, IFCC Correlated

Mean −− 29.96 −− 142.6 −− 298.8
SD
CV
1 −−
−−
1.85
6.2
2−−
−−
5.85
4.1
3 −−
−−
7.15
2.4
# Points −− 22 −− 23 −− 22
# Labs 1 2 1
Abbott ARCHITECT/Alinity (c, i, ci models) • Wako

Mean 29.07 29.13 145.2 144.9 306.4 304.0
SD
CV
1 0.450
1.5
0.713
2.4
2 2.43
1.7
1.85
1.3
3 3.69
1.2
4.50
1.5
# Points 26 416 26 458 26 463
# Labs 1 1 1 1 1 1


Mean −− −− −− 137.6 −− 295.9
SD
CV
1 −−
−−
−−
−−
2 −−
−−
3.49
2.5
3 −−
−−
7.30
2.5
# Points −− −− −− 549 −− 545
# Labs 2 2

Mean 21.62 24.72 129.3 139.4 286.5 299.6
SD
CV
1 2.61
12.1
2.85
11.5
2 9.41
7.3
10.56
7.6
3 15.90
5.5
20.01
6.7
# Points 1830 69498 1500 40446 763 64600
# Labs 63 212 51 132 27 180

Mean 27.77 27.93 149.7 156.3 326.5 334.3
SD
CV
1 2.49
9.0
2.53
9.1
2 6.21
4.2
8.87
5.7
3 14.97
4.6
17.47
5.2
# Points 86 30795 205 38121 268 40262
# Labs 6 78 6 93 9 100

Mean −− 26.51 −− −− −− 330.7
SD
CV
1 −−
−−
1.81
6.8
2 −−
−−
−−
−−
3 −−
−−
18.94
5.7
# Points −− 213 −− −− −− 213
# Labs 1 1

Mean −− 28.13 −− 144.7 −− 309.0
SD
CV
1 −−
−−
1.89
6.7
2 −−
−−
8.03
5.5
3 −−
−−
17.36
5.6
# Points −− 200 −− 200 −− 199
# Labs 1 1 1

Mean 30.33 31.20 139.7 141.0 292.0 289.8
SD
CV
1 1.44
4.8
1.53
4.9
2 4.24
3.0
5.23
3.7
3 7.27
2.5
8.47
2.9
# Points 62 667 62 689 62 690
# Labs 2 2 2 2 2 2

Mean −− −− 140.2 138.1 296.8 295.6
SD
CV
1 −−
−−
−−
−−
2 2.17
1.5
4.19
3.0
3 1.71
0.6
7.92
2.7
# Points −− −− 5 732 4 731
# Labs 1 2 1 2

Mean 22.45 23.83 −− 144.6 292.8 298.3
SD
CV
1 2.73
12.2
2.34
9.8
2 −−
−−
11.62
8.0
3 21.30
7.3
16.09
5.4
# Points 71 10310 −− 2368 65 9535
# Labs 2 33 8 2 30
Dirui CS Series
Mean −− 28.23 −− 140.3 −− 292.6
SD
CV
1 −−
−−
1.96
6.9
2 −−
−−
6.03
4.3
3 −−
−−
10.77
3.7
# Points −− 877 −− 868 −− 873
# Labs 2 2 2

Mean −− −− 139.0 136.8 295.4 294.6
SD
CV
1 −−
−−
−−
−−
2 4.76
3.4
5.97
4.4
3 9.95
3.4
11.83
4.0
# Points −− −− 45 241 42 242
# Labs 3 3 3 3


ERBA XL−640
Mean −− 22.73 −− 128.3 −− −−
SD
CV
1 −−
−−
1.51
6.6
2 −−
−−
11.00
8.6
3 −−
−−
−−
−−
# Points −− 42 −− 42 −− −−
# Labs 1 1

Mean −− 34.22 −− 145.3 −− 207.1
SD
CV
1 −−
−−
3.56
10.4
2 −−
−−
11.26
7.7
3 −−
−−
10.87
5.2
# Points −− 130 −− 86 −− 49
# Labs 2 2 1
Fuji Dri−Chem Series • Fuji Dri−Chem ALP−PIII, REF 9903021

Mean 96.00 90.76 330.0 356.9 −− −−
SD
CV
1 0.000
0.0
6.09
6.7
2
0.000
0.0
19.71
5.5
3 −−
−−
−−
−−
# Points 1 37 1 42 −− −−
# Labs 1 2 1 2

Mean −− 25.00 −− −− −− 272.0
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− 1 −− −− −− 1
# Labs 1 1

Mean −− −− −− 147.2 −− 321.3
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.95
2.0
3 −−
−−
5.81
1.8
# Points −− −− −− 106 −− 106
# Labs 1 1

Mean −− 30.08 −− −− −− 268.2
SD
CV
1 −−
−−
1.66
5.5
2 −−
−−
−−
−−
3 −−
−−
12.50
4.7
# Points −− 37 −− −− −− 37
# Labs 1 1
Mindray BS Series
Mean −− 31.55 −− 165.6 −− 352.8
SD
CV
1 −−
−−
3.24
10.3
2 −−
−−
6.70
4.0
3 −−
−−
13.60
3.9
# Points −− 100 −− 323 −− 320
# Labs 1 2 2
Mindray CL Series
Mean −− −− −− 154.1 −− 335.0
SD
CV
1 −−
−−
−−
−−
2 −−
−−
5.40
3.5
3 −−
−−
11.16
3.3
# Points −− −− −− 87 −− 88
# Labs 1 1

Mean −− −− −− 136.0 −− 291.0
SD
CV
1 −−
−−
−−
−−
2 −−
−−
4.12
3.0
3 −−
−−
7.93
2.7
# Points −− −− −− 249 −− 244
# Labs 2 2
Roche cobas 6000/c 311

Mean 28.86 30.43 139.4 142.8 288.2 294.5
SD
CV
1 2.09
7.3
2.17
7.1
2 4.99
3.6
5.66
4.0
3 9.90
3.4
10.28
3.5
# Points 529 26195 124 15901 509 26744
# Labs 11 79 5 52 9 78


Roche cobas 6000/c 311 • 2nd Generation
Mean −− 32.16 −− −− −− 309.5
SD
CV
1 −−
−−
1.50
4.7
2 −−
−−
−−
−−
3 −−
−−
9.11
2.9
# Points −− 861 −− −− −− 835
# Labs 4 4
Roche cobas 8000

Mean 28.60 29.91 149.0 137.5 294.3 291.3
SD
CV
1 1.96
6.8
2.07
6.9
2 6.75
4.5
7.50
5.5
3 10.91
3.7
11.82
4.1
# Points 75 12241 107 4944 176 15522
# Labs 2 27 1 17 3 37
Roche cobas 8000 • BC AU Calibrator 66300

Mean −− 29.72 −− 137.9 −− 286.2
SD
CV
1 −−
−−
1.80
6.1
2 −−
−−
5.61
4.1
3 −−
−−
10.63
3.7
# Points −− 190 −− 187 −− 187
# Labs 1 1 1

Mean 29.24 29.21 132.9 131.5 267.6 269.1
SD
CV
1 1.85
6.3
1.89
6.5
2 3.56
2.7
4.55
3.5
3 6.08
2.3
7.70
2.9
# Points 57 5103 62 4805 49 5000
# Labs 2 14 2 11 2 14

Mean 29.47 30.42 143.4 141.7 297.7 291.4
SD
CV
1 1.78
6.1
2.71
8.9
2 4.56
3.2
7.77
5.5
3 5.68
1.9
15.01
5.2
# Points 110 646 111 912 109 933
# Labs 3 4 3 4 3 5

Mean 28.79 29.85 141.0 145.3 292.7 298.8
SD
CV
1 1.68
5.8
2.39
8.0
2 2.00
1.4
4.07
2.8
3 7.21
2.5
12.17
4.1
# Points 67 2976 32 812 67 2992
# Labs 2 9 1 2 2 9

Mean −− 32.37 −− −− −− 309.4
SD
CV
1 −−
−−
1.22
3.8
2 −−
−−
−−
−−
3 −−
−−
7.10
2.3
# Points −− 126 −− −− −− 123
# Labs 1 1

Mean 30.26 29.43 141.8 136.3 297.5 298.1
SD
CV
1 0.960
3.2
4.73
16.1
2 2.88
2.0
17.88
13.1
3 2.76
0.9
37.88
12.7
# Points 31 952 31 948 31 851
# Labs 1 4 1 4 1 3
Roche Hitachi Systems (International) • LEADMAN

Mean −− 31.27 −− 144.5 −− 301.8
SD
CV
1 −−
−−
1.13
3.6
2 −−
−−
2.21
1.5
3 −−
−−
4.77
1.6
# Points −− 631 −− 631 −− 630
# Labs 2 2 2
Roche Hitachi Systems (International) • Maccura

Mean −− −− −− 156.1 −− 330.0
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.84
1.8
3 −−
−−
5.38
1.6
# Points −− −− −− 334 −− 334
# Labs 1 1


Mean −− −− −− 149.8 −− 310.9
SD
CV
1 −−
−−
−−
−−
2 −−
−−
4.96
3.3
3 −−
−−
9.22
3.0
# Points −− −− −− 371 −− 373
# Labs 1 1

Mean −− −− −− 161.0 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
6.45
4.0
3 −−
−−
−−
−−
# Points −− −− −− 25 −− −−
# Labs 1

Mean 29.95 31.60 123.4 133.8 254.5 281.1
SD
CV
1 1.79
6.0
2.74
8.7
2 5.39
4.4
8.88
6.6
3 8.88
3.5
16.71
5.9
# Points 22 1483 57 1704 54 2191
# Labs 1 8 2 9 2 10
Siemens ADVIA Chemistry Systems • Abbott ARCH Alk Phos REF 7D55 (Factored, IFCC Correlated)
Mean −− 30.31 −− 148.5 −− 314.2
SD
CV
1 −−
−−
5.12
16.9
−−
−−
211.56
7.8
3 −−
−−
22.25
7.1
# Points −− 88 −− 88 −− 88
# Labs 1 1 1
Siemens ADVIA Chemistry Systems • Abbott ARCH AlkP2, REF 04S87 (Factored, IFCC Correlated)
Mean −− 31.10 −− 156.7 −− 327.0
SD
CV
1 −−
−−
0.000
0.0
−−
−−
20.000
0.0
3 −−
−−
0.000
0.0
# Points −− 1 −− 1 −− 1
# Labs 1 1 1

Mean −− 28.51 −− 131.9 −− 272.5
SD
CV
1 −−
−−
2.55
8.9
2 −−
−−
5.39
4.1
3 −−
−−
9.02
3.3
# Points −− 3032 −− 2547 −− 3053
# Labs 9 4 9

Mean 28.10 29.51 127.6 134.4 267.7 280.1
SD
CV
1 2.17
7.7
2.76
9.4
2 3.61
2.8
6.38
4.7
3 9.31
3.5
10.05
3.6
# Points 201 17857 75 3405 137 16132
# Labs 7 51 4 11 5 46

Mean 26.62 29.48 −− 134.6 263.4 273.7
SD
CV
1 2.09
7.9
2.44
8.3
2 −−
−−
6.00
4.5
3 9.69
3.7
11.77
4.3
# Points 571 38227 −− 6873 574 36913
# Labs 17 82 14 17 80

Mean −− 25.09 −− 105.3 −− 213.3
SD
CV
1 −−
−−
3.17
12.7
2 −−
−−
4.62
4.4
3 −−
−−
7.93
3.7
# Points −− 110 −− 109 −− 109
# Labs 1 1 1

Mean −− 28.90 −− 145.5 −− 311.1
SD
CV
1 −−
−−
2.96
10.2
2 −−
−−
5.79
4.0
3 −−
−−
9.51
3.1
# Points −− 464 −− 468 −− 472
# Labs 3 3 3


Mean −− 30.79 −− 129.3 −− 227.5
SD
CV
1 −−
−−
1.50
4.9
2 −−
−−
3.71
2.9
3 −−
−−
5.91
2.6
# Points −− 302 −− 298 −− 296
# Labs 3 3 3

Mean −− 33.43 −− 135.7 −− 236.6
SD
CV
1 −−
−−
1.30
3.9
2 −−
−−
4.21
3.1
3 −−
−−
6.84
2.9
# Points −− 265 −− 269 −− 261
# Labs 3 3 3

Mean −− 32.57 −− 128.9 −− 229.6
SD
CV
1 −−
−−
1.38
4.2
2 −−
−−
4.08
3.2
3 −−
−−
6.82
3.0
# Points −− 280 −− 280 −− 278
# Labs 3 3 3

Mean −− 31.56 −− 128.6 −− 228.0
SD
CV
1 −−
−−
1.41
4.5
2 −−
−−
3.88
3.0
3 −−
−−
6.67
2.9
# Points −− 671 −− 674 −− 669
# Labs 3 3 3

Mean −− 33.78 −− 122.3 −− 214.3
SD
CV
1 −−
−−
1.51
4.5
2 −−
−−
4.88
4.0
3 −−
−−
8.48
4.0
# Points −− 170 −− 171 −− 169
# Labs 3 3 3

Mean −− 35.43 −− 138.5 −− 249.8
SD
CV
1 −−
−−
0.828
2.3
2 −−
−−
2.40
1.7
3 −−
−−
5.92
2.4
# Points −− 58 −− 58 −− 65
# Labs 1 1 1

Mean −− 34.40 −− −− −− 250.0
SD
CV
1 −−
−−
0.849
2.5
2 −−
−−
−−
−−
3 −−
−−
2.12
0.8
# Points −− 2 −− −− −− 2
# Labs 1 1

Mean −− 33.86 −− −− −− 252.0
SD
CV
1 −−
−−
0.668
2.0
2 −−
−−
−−
−−
3 −−
−−
5.00
2.0
# Points −− 19 −− −− −− 19
# Labs 1 1

Mean −− 25.20 −− 131.8 −− −−
SD
CV
1 −−
−−
4.46
17.7
2 −−
−−
9.83
7.5
3 −−
−−
−−
−−
# Points −− 160 −− 160 −− −−
# Labs 1 1

Mean 25.67 28.08 135.0 143.6 286.4 297.0
SD
CV
1 4.10
16.0
3.51
12.5
2 10.91
8.1
12.14
8.5
3 19.73
6.9
23.77
8.0
# Points 5168 284K 3311 160K 3777 289K
# Labs 168 845 117 527 116 808


Toshiba−TBA • DiaSys Diagnostic Systems
Mean 26.00 24.43 −− −− 295.0 273.8
SD
CV
1 1.73
6.7
1.34
5.5
2 −−
−−
−−
−−
3 0.000
0.0
7.80
2.9
# Points 3 345 −− −− 1 343
# Labs 1 1 1 1

Mean 26.00 24.43 −− −− 295.0 273.8
SD
CV
1 1.73
6.7
1.34
5.5
2 −−
−−
−−
−−
3 0.000
0.0
7.80
2.9
# Points 3 345 −− −− 1 343
# Labs 1 1 1 1
Alkaline Phosphatase PNPP, AMP Buffer − IFCC Ref. Proc., Calibrated U/L @ 25° C
Mean −− 24.81 −− 139.3 −− 297.2
SD
CV
1 −−
−−
1.81
7.3
2 −−
−−
4.59
3.3
3 −−
−−
6.99
2.4
# Points −− 37 −− 37 −− 37
# Labs 1 1 1

Mean 26.03 27.19 −− 133.9 279.9 281.7
SD
CV
1 1.03
4.0
1.42
5.2
2 −−
−−
5.38
4.0
3 5.57
2.0
7.57
2.7
# Points 67 763 −− 133 67 785
# Labs 2 2 1 2 3
Method Group • PNPP, AMP Buffer − IFCC Ref. Proc., Calibrated

Mean 26.03 27.08 −− 135.1 279.9 282.4
SD
CV
1 1.03
4.0
1.52
5.6
2
−−
−−
5.67
4.2
3 5.57
2.0
8.20
2.9
# Points 67 800 −− 170 67 822
# Labs 2 3 2 2 4
Mean 30.91 31.04 141.8 147.6 299.7 308.3
SD
CV
1 2.18
7.0
2.28
7.4
2 4.19
3.0
6.89
4.7
3 6.50
2.2
11.86
3.8
# Points 34 7745 34 8037 34 7875
# Labs 5 23 5 23 5 23
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH AlkP2 REF 04S87

Mean 26.06 27.70 136.8 140.6 −− −−
SD
CV
1 1.31
5.0
1.75
6.3
2
2.04
1.5
4.79
3.4
3 −−
−−
−−
−−
# Points 15 80 15 80 −− −−
# Labs 1 2 1 2
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH AlkP2, REF 04S87 (Factored, IFCC Correlated)
Mean 26.62 26.78 138.4 139.0 −− −−
SD
CV
1 1.23
4.6
1.07
4.0
2
2.71
2.0
2.62
1.9
3 −−
−−
−−
−−
# Points 106 394 106 318 −− −−
# Labs 3 3 3 3
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c AlkP, REF 08P20 (Factored, IFCC Correlated)
Mean −− 25.28 −− 130.1 −− −−
SD
CV
1 −−
−−
3.28
13.0
2 −−
−−
4.80
3.7
3 −−
−−
−−
−−
# Points −− 83 −− 82 −− −−
# Labs 2 1

Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c AlkP2, REF 04T83 (Factored, IFCC Correlated)
Mean 27.75 28.35 139.8 141.0 300.6 307.3
SD
CV
1 2.57
9.3
2.71
9.5
2 7.15
5.1
9.21
6.5
3 10.55
3.5
12.19
4.0
# Points 262 742 292 653 93 322
# Labs 11 16 12 16 5 7
Abbott ARCHITECT/Alinity (c, i, ci models) • Alternate Formulation/Standardization

Mean 29.58 28.61 146.5 144.0 −− −−
SD
CV
1 2.53
8.6
2.66
9.3
2 4.46
3.0
7.78
5.4
3 −−
−−
−−
−−
# Points 26 148 26 147 −− −−
# Labs 1 1 1 1

Mean 28.50 29.03 141.6 139.9 298.3 295.4
SD
CV
1 2.10
7.4
2.82
9.7
2 5.25
3.7
8.49
6.1
3 10.20
3.4
14.80
5.0
# Points 286 5892 214 5293 188 5341
# Labs 7 19 7 18 5 13
Abbott ARCHITECT/Alinity (c, i, ci models) • Shinotest

Mean −− 32.26 −− 151.2 −− 313.3
SD
CV
1 −−
−−
1.67
5.2
2 −−
−−
4.65
3.1
3 −−
−−
7.21
2.3
# Points −− 272 −− 272 −− 272
# Labs 1 1 1

Mean 25.57 26.79 154.9 154.5 323.2 324.4
SD
CV
1 2.67
10.5
3.04
11.3
2 4.83
3.1
8.51
5.5
3 21.69
6.7
22.94
7.1
# Points 283 16577 210 13933 266 16860
# Labs 7 51 5 39 8 49

Mean −− 28.44 −− 153.0 −− 331.6
SD
CV
1 −−
−−
2.29
8.1
2 −−
−−
5.20
3.4
3 −−
−−
13.46
4.1
# Points −− 1243 −− 936 −− 1811
# Labs 8 7 10

Mean −− −− −− 134.9 −− 292.9
SD
CV
1 −−
−−
−−
−−
2 −−
−−
9.07
6.7
3 −−
−−
17.17
5.9
# Points −− −− −− 175 −− 175
# Labs 1 1

Mean −− 30.68 −− 145.4 −− 300.2
SD
CV
1 −−
−−
2.61
8.5
2 −−
−−
5.97
4.1
3 −−
−−
12.25
4.1
# Points −− 3117 −− 2894 −− 3130
# Labs 8 7 8
Hitachi Chemistry Series • Kanto Kagaku

Mean −− 30.95 −− −− −− −−
SD
CV
1 −−
−−
0.907
2.9
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 64 −− −− −− −−
# Labs 1

Mean −− 27.12 −− −− −− 319.2
SD
CV
1 −−
−−
2.06
7.6
2 −−
−−
−−
−−
3 −−
−−
13.88
4.3
# Points −− 90 −− −− −− 92
# Labs 1 1

Mindray BS Series
Mean −− 27.06 −− 318.4 −− −−
SD
CV
1 −−
−−
1.65
6.1
2 −−
−−
9.45
3.0
3 −−
−−
−−
−−
# Points −− 248 −− 240 −− −−
# Labs 1 1
RANDOX RX imola
Mean 21.73 22.92 134.9 134.3 −− −−
SD
CV
1 1.48
6.8
1.74
7.6
2 3.11
2.3
3.44
2.6
3 −−
−−
−−
−−
# Points 26 224 24 193 −− −−
# Labs 1 1 1 1

Mean 27.46 29.89 136.0 140.9 285.1 293.5
SD
CV
1 2.03
7.4
2.54
8.5
2 5.45
4.0
7.45
5.3
3 9.74
3.4
12.47
4.2
# Points 1120 20856 217 9646 1073 20841
# Labs 22 61 6 29 20 59
Roche cobas 8000

Mean 27.05 28.92 −− 140.0 282.9 289.3
SD
CV
1 1.40
5.2
1.98
6.9
2 −−
−−
6.06
4.3
3 8.72
3.1
9.76
3.4
# Points 974 27363 −− 9291 983 29043
# Labs 17 39 22 17 44

Mean 28.25 29.24 131.9 133.5 269.1 272.5
SD
CV
1 1.19
4.2
1.64
5.6
2 3.09
2.3
3.83
2.9
3 6.14
2.3
7.79
2.9
# Points 84 2196 28 1265 80 1985
# Labs 3 6 1 2 3 6
Roche cobas c 303/503 • Roche ALP2, REF 08056757

Mean 26.09 28.36 126.2 130.5 263.0 265.9
SD
CV
1 1.65
6.3
2.36
8.3
2 4.18
3.3
4.78
3.7
3 5.08
1.9
10.13
3.8
# Points 351 11521 93 4098 176 11180
# Labs 10 35 3 9 6 31

Mean 27.68 31.35 134.2 139.2 285.9 286.7
SD
CV
1 1.56
5.6
5.30
16.9
2 4.72
3.5
4.94
3.5
3 6.44
2.3
6.84
2.4
# Points 96 1197 102 1269 14 266
# Labs 2 2 2 2 1 1

Mean 27.00 30.45 −− −− 285.0 298.3
SD
CV
1 3.00
11.1
2.93
9.6
2 −−
−−
−−
−−
3 8.00
2.8
10.15
3.4
# Points 20 618 −− −− 20 620
# Labs 1 2 1 2

Mean −− 32.14 −− −− −− 310.3
SD
CV
1 −−
−−
0.913
2.8
2 −−
−−
−−
−−
3 −−
−−
4.41
1.4
# Points −− 37 −− −− −− 37
# Labs 1 1
Mean −− 29.30 −− 145.3 −− 301.6
SD
CV
1 −−
−−
2.68
9.1
2 −−
−−
8.97
6.2
3 −−
−−
19.52
6.5
# Points −− 263 −− 264 −− 266
# Labs 1 1 1

Roche Hitachi/MODULAR • Shinotest
Mean −− 25.99 −− −− −− 283.1
SD
CV
1 −−
−−
1.69
6.5
2 −−
−−
−−
−−
3 −−
−−
9.70
3.4
# Points −− 279 −− −− −− 278
# Labs 1 1

Mean 27.14 29.08 125.4 131.3 284.2 279.2
SD
CV
1 1.28
4.7
2.58
8.9
2 4.05
3.2
6.15
4.7
3 5.94
2.1
12.07
4.3
# Points 124 15198 63 10794 65 14557
# Labs 4 31 3 25 2 27
Siemens ADVIA Chemistry Systems • Abbott ARCH Alk Phos REF 7D55 (Factored, IFCC Correlated)
Mean −− 30.88 −− 153.1 −− 322.5
SD
CV
1 −−
−−
3.52
11.4
−−
−−
2 8.58
5.6
3 −−
−−
15.48
4.8
# Points −− 238 −− 239 −− 234
# Labs 1 1 1

Mean 25.71 29.11 120.5 131.6 258.7 274.0
SD
CV
1 1.64
6.4
2.57
8.8
2 5.37
4.5
7.43
5.6
3 9.31
3.6
11.95
4.4
# Points 559 29230 463 15566 235 20414
# Labs 17 86 15 64 10 68

Mean 26.07 29.34 129.1 134.7 270.6 278.4
SD
CV
1 2.72
10.4
2.74
9.4
2 9.09
7.0
5.82
4.3
3 10.12
3.7
10.13
3.6
# Points 1401 113K 273 14318 1346 77698
# Labs 48 216 10 53 44 189
Siemens Dimension Series • Alternate Formulation/Standardization

Mean −− 30.55 −− −− −− 285.7
SD
CV
1 −−
−−
2.37
7.8
2
−−
−−
−−
−−
3 −−
−−
8.23
2.9
# Points −− 1852 −− −− −− 1806
# Labs 2 2

Mean 26.44 29.07 127.5 134.3 261.1 273.0
SD
CV
1 1.69
6.4
2.41
8.3
2 5.77
4.5
6.38
4.7
3 7.67
2.9
10.95
4.0
# Points 2372 197K 785 57094 2140 186K
# Labs 65 389 23 115 61 373
Thermo Konelab 20/30/60i

Mean −− −− 136.1 135.7 −− −−
SD
CV
1 −−
−−
−−
−−
2 7.79
5.7
8.29
6.1
3 −−
−−
−−
−−
# Points −− −− 15 23 −− −−
# Labs 1 1
Toshiba−TBA
Mean −− −− −− −− −− 286.5
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
6.26
2.2
# Points −− −− −− −− −− 74
# Labs 1

Mean −− −− −− 136.8 −− 255.5
SD
CV
1 −−
−−
−−
−−
2 −−
−−
4.09
3.0
3 −−
−−
7.51
2.9
# Points −− −− −− 92 −− 84
# Labs 2 2

Method Group • PNPP, AMP Buffer − IFCC Ref. Proc., Calibrated
Mean 26.66 29.11 132.3 137.9 274.7 280.2
SD
CV
1 2.15
8.1
2.61
9.0
2
10.88
8.2
11.93
8.7
3 17.85
6.5
17.47
6.2
# Points 8113 457K 2934 158K 6713 401K
# Labs 224 1011 98 448 188 923
Alkaline Phosphatase PNPP, AMP Buffer−VITROS U/L @ 25° C

Mean −− 38.17 −− −− −− 258.7
SD
CV
1 −−
−−
1.61
4.2
2 −−
−−
−−
−−
3 −−
−−
5.12
2.0
# Points −− 166 −− −− −− 147
# Labs 1 1

Mean −− 38.41 −− −− −− 258.9
SD
CV
1 −−
−−
1.37
3.6
2 −−
−−
−−
−−
3 −−
−−
5.17
2.0
# Points −− 85 −− −− −− 86
# Labs 1 1
Method Group • PNPP, AMP Buffer−VITROS

Mean −− 38.25 −− −− −− 258.8
SD
CV
1 −−
−−
1.53
4.0
2 −−
−−
−−
−−
3 −−
−−
5.13
2.0
# Points −− 251 −− −− −− 233
# Labs 2 2

Mean 35.30 33.81 153.6 154.2 226.2 232.9
SD
CV
1 0.900
2.5
3.02
8.9
2 0.850
0.6
15.26
9.9
3 5.60
2.5
13.46
5.8
# Points 15 1079 3 916 15 868
# Labs 1 15 1 9 1 8

Mean −− 40.65 −− −− −− 281.9
SD
CV
1 −−
−−
1.10
2.7
2 −−
−−
−−
−−
3 −−
−−
7.90
2.8
# Points −− 24 −− −− −− 24
# Labs 1 1

Mean −− 35.18 −− −− −− 255.1
SD
CV
1 −−
−−
2.08
5.9
2 −−
−−
−−
−−
3 −−
−−
9.67
3.8
# Points −− 340 −− −− −− 462
# Labs 2 2

Mean −− 43.09 −− −− −− 262.1
SD
CV
1 −−
−−
1.81
4.2
2 −−
−−
−−
−−
3 −−
−−
5.42
2.1
# Points −− 192 −− −− −− 154
# Labs 1 1

Mean −− 36.24 −− −− −− 244.9
SD
CV
1 −−
−−
1.83
5.0
2 −−
−−
−−
−−
3 −−
−−
3.65
1.5
# Points −− 13 −− −− −− 8
# Labs 1 1


Mean 40.52 34.01 138.0 133.8 −− 241.8
SD
CV
1 0.871
2.1
2.98
8.8
2 2.65
1.9
6.62
4.9
3 −−
−−
13.55
5.6
# Points 75 1754 76 1186 −− 1279
# Labs 2 12 2 9 11

Mean −− 33.79 −− 141.8 −− 243.3
SD
CV
1 −−
−−
2.61
7.7
2 −−
−−
9.91
7.0
3 −−
−−
12.24
5.0
# Points −− 3860 −− 1181 −− 3819
# Labs 22 11 22

Mean 35.23 32.84 −− 133.9 234.0 238.6
SD
CV
1 2.06
5.9
2.23
6.8
2 −−
−−
6.01
4.5
3 10.40
4.4
16.35
6.9
# Points 59 2234 −− 1120 62 2391
# Labs 2 16 8 2 14

Mean 30.41 31.01 −− 129.2 245.3 233.1
SD
CV
1 1.66
5.5
1.73
5.6
2 −−
−−
4.09
3.2
3 7.08
2.9
9.73
4.2
# Points 24 1840 −− 431 19 1610
# Labs 1 14 8 1 15

Mean 34.89 33.32 133.4 132.5 232.3 229.8
SD
CV
1 1.84
5.3
2.75
8.3
2 4.83
3.6
6.02
4.5
3 8.82
3.8
10.80
4.7
# Points 186 1963 86 626 138 1710
# Labs 9 12 5 5 8 12

Mean 38.45 35.30 138.2 138.9 239.1 238.3
SD
CV
1 1.63
4.2
2.02
5.7
2 4.01
2.9
3.85
2.8
3 7.04
2.9
5.72
2.4
# Points 44 252 42 74 21 234
# Labs 4 7 4 6 3 6

Mean 33.86 34.58 134.0 134.7 233.1 241.9
SD
CV
1 0.971
2.9
2.06
6.0
2 2.87
2.1
6.68
5.0
3 6.05
2.6
10.64
4.4
# Points 53 17338 32 6510 54 17060
# Labs 2 113 1 44 2 103

Mean 37.00 33.81 149.0 137.2 262.3 241.9
SD
CV
1 0.900
2.4
2.16
6.4
2 2.80
1.9
6.50
4.7
3 7.78
3.0
10.91
4.5
# Points 31 12354 30 4040 50 12314
# Labs 1 81 1 31 2 77

Mean −− 35.35 −− 139.5 −− 246.1
SD
CV
1 −−
−−
2.15
6.1
2 −−
−−
5.15
3.7
3 −−
−−
11.24
4.6
# Points −− 6651 −− 2562 −− 6035
# Labs 57 18 55

Mean 35.33 35.38 131.0 134.7 236.3 240.2
SD
CV
1 2.36
6.7
1.96
5.5
2 4.87
3.7
6.30
4.7
3 13.15
5.6
11.84
4.9
# Points 610 13454 244 4578 623 12259
# Labs 25 85 11 32 23 72


Mean −− 34.63 −− 138.0 −− 252.8
SD
CV
1 −−
−−
2.28
6.6
2 −−
−−
4.98
3.6
3 −−
−−
10.61
4.2
# Points −− 831 −− 401 −− 891
# Labs 14 8 15

Mean 34.33 34.12 131.6 134.5 234.3 238.3
SD
CV
1 3.29
9.6
2.22
6.5
2 6.25
4.7
6.96
5.2
3 8.68
3.7
11.04
4.6
# Points 105 3725 55 1621 22 3191
# Labs 7 44 3 20 2 37

Mean 33.73 33.75 133.8 132.3 229.9 233.3
SD
CV
1 2.47
7.3
2.26
6.7
2 4.92
3.7
5.79
4.4
3 7.95
3.5
11.65
5.0
# Points 265 4183 190 2731 171 3524
# Labs 9 36 7 23 6 26

Mean 39.25 39.69 132.4 133.3 239.1 242.4
SD
CV
1 1.61
4.1
1.72
4.3
2 4.46
3.4
4.86
3.6
3 15.15
6.3
14.55
6.0
# Points 147 303 75 167 105 265
# Labs 8 9 5 5 6 7

Mean 35.39 35.39 136.1 136.1 231.5 231.5
SD
CV
1 2.20
6.2
2.20
6.2
2 0.000
0.0
0.000
0.0
3 9.88
4.3
9.88
4.3
# Points 4 4 1 1 2 2
# Labs 2 2 1 1 2 2

Mean −− −− −− −− −− 268.0
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− −− −− −− −− 1
# Labs 1

Mean −− 35.15 −− −− −− 252.2
SD
CV
1 −−
−−
1.11
3.2
2 −−
−−
−−
−−
3 −−
−−
5.45
2.2
# Points −− 93 −− −− −− 93
# Labs 1 1

Mean −− 33.72 −− −− −− 234.7
SD
CV
1 −−
−−
1.53
4.5
2 −−
−−
−−
−−
3 −−
−−
5.73
2.4
# Points −− 62 −− −− −− 65
# Labs 1 1
Method Group • PNPP, AMP Buffer−VITROS

Mean 35.54 34.40 133.9 136.0 236.0 240.9
SD
CV
1 2.94
8.3
2.43
7.1
2 6.02
4.5
8.06
5.9
3 13.00
5.5
12.13
5.0
# Points 1618 72451 834 28109 1282 67937
# Labs 73 545 41 238 58 488
Alkaline Phosphatase PNPP, DEA Buffer U/L @ 37° C

Mean 64.13 60.38 197.9 191.1 399.6 388.7
SD
CV
1 5.47
8.5
5.02
8.3
2 18.69
9.4
15.50
8.1
3 12.18
3.0
27.95
7.2
# Points 53 717 39 566 5 42
# Labs 3 4 3 4 1 2

Alkaline Phosphatase PNPP, DEA Buffer U/L @ 37° C

Mean −− −− −− 143.8 −− 309.8
SD
CV
1 −−
−−
−−
−−
2 −−
−−
10.74
7.5
3 −−
−−
22.93
7.4
# Points −− −− −− 189 −− 190
# Labs 1 1
RANDOX RX daytona
Mean 62.55 57.24 189.9 179.8 356.0 356.0
SD
CV
1 5.05
8.1
7.04
12.3
2 12.66
6.7
23.47
13.1
3 0.000
0.0
0.000
0.0
# Points 20 159 16 128 1 1
# Labs 1 1 1 1 1 1

Mean −− 58.66 −− 200.3 −− 390.4
SD
CV
1 −−
−−
6.30
10.7
2 −−
−−
11.56
5.8
3 −−
−−
42.73
10.9
# Points −− 113 −− 112 −− 114
# Labs 2 2 2
Siemens ADVIA Chemistry Systems • DiaSys Diagnostic Systems

Mean −− 65.80 −− 233.1 −− 467.7
SD
CV
1 −−
−−
4.93
7.5
−−
−−
2 13.35
5.7
3 −−
−−
24.42
5.2
# Points −− 17 −− 17 −− 17
# Labs 1 1 1
Method Group • PNPP, DEA Buffer

Mean 63.70 59.78 195.5 182.5 392.3 351.7
SD
CV
1 5.37
8.4
5.71
9.5
2 17.43
8.9
25.36
13.9
3 20.87
5.3
55.97
15.9
# Points 73 1006 55 1012 6 364
# Labs 4 8 4 9 2 7
Alkaline Phosphatase PNPP, EAE Buffer − JSCC U/L @ 37° C

Mean −− 91.88 −− −− −− 603.3
SD
CV
1 −−
−−
5.94
6.5
2 −−
−−
−−
−−
3 −−
−−
28.26
4.7
# Points −− 1773 −− −− −− 1787
# Labs 4 4
Method Group • PNPP, EAE Buffer − JSCC

Mean −− 91.88 −− −− −− 603.3
SD
CV
1 −−
−−
5.94
6.5
2 −−
−−
−−
−−
3 −−
−−
28.26
4.7
# Points −− 1773 −− −− −− 1787
# Labs 4 4
Alpha−1−Globulin Agarose Gel %

Interlab G26
Mean −− 1.90 −− 2.17 −− 2.22
SD
CV
1 −−
−−
0.240
12.6
2 −−
−−
0.220
10.1
3 −−
−−
0.260
11.7
# Points −− 4 −− 4 −− 4
# Labs 1 1 1

Mean −− 1.90 −− 2.17 −− 2.22
SD
CV
1 −−
−−
0.240
12.6
2 −−
−−
0.220
10.1
3 −−
−−
0.260
11.7
# Points −− 4 −− 4 −− 4
# Labs 1 1 1

Alpha−1−Globulin REP Gel %

Helena REP
Mean −− −− −− 5.05 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.722
14.3
3 −−
−−
−−
−−
# Points −− −− −− 86 −− −−
# Labs 1

Mean −− −− −− 5.05 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.722
14.3
3 −−
−−
−−
−−
# Points −− −− −− 86 −− −−
# Labs 1
Alpha−2−Globulin Agarose Gel %

Interlab G26
Mean −− 8.77 −− 9.45 −− 11.23
SD
CV
1 −−
−−
0.560
6.4
2 −−
−−
0.370
3.9
3 −−
−−
0.800
7.1
# Points −− 4 −− 4 −− 4
# Labs 1 1 1

Mean −− 8.77 −− 9.45 −− 11.23
SD
CV
1 −−
−−
0.560
6.4
2 −−
−−
0.370
3.9
3 −−
−−
0.800
7.1
# Points −− 4 −− 4 −− 4
# Labs 1 1 1
Alpha−2−Globulin REP Gel %

Helena REP
Mean −− −− −− 10.58 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.04
19.2
3 −−
−−
−−
−−
# Points −− −− −− 86 −− −−
# Labs 1

Mean −− −− −− 10.58 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.04
19.2
3 −−
−−
−−
−−
# Points −− −− −− 86 −− −−
# Labs 1
ALT (ALAT/GPT) Dinitrophenyl hydrazine U/L @ 25° C

Mean 23.90 24.24 81.60 81.99 169.1 168.3
SD
CV
1 0.680
2.8
0.666
2.7
2 2.48
3.0
1.80
2.2
3 3.87
2.3
3.53
2.1
# Points 21 123 22 122 19 119
# Labs 1 1 1 1 1 1
Method Group • Dinitrophenyl hydrazine

Mean 23.90 24.24 81.60 81.99 169.1 168.3
SD
CV
1 0.680
2.8
0.666
2.7
2 2.48
3.0
1.80
2.2
3 3.87
2.3
3.53
2.1
# Points 21 123 22 122 19 119
# Labs 1 1 1 1 1 1

Mean −− 25.73 −− −− −− 176.6
SD
CV
1 −−
−−
1.29
5.0
2 −−
−−
−−
−−
3 −−
−−
2.92
1.7
# Points −− 225 −− −− −− 234
# Labs 1 1


Mean −− 29.23 −− 91.71 −− 189.2
SD
CV
1 −−
−−
1.23
4.2
2 −−
−−
3.39
3.7
3 −−
−−
6.65
3.5
# Points −− 61 −− 61 −− 61
# Labs 1 1 1

Mean −− 26.48 −− 91.71 −− 179.2
SD
CV
1 −−
−−
1.92
7.3
2 −−
−−
3.39
3.7
3 −−
−−
6.47
3.6
# Points −− 286 −− 61 −− 295
# Labs 2 1 2
ALT (ALAT/GPT) Enzymatic, colorimetric U/L @ 25° C

Mean −− 25.26 −− −− −− 177.0
SD
CV
1 −−
−−
1.54
6.1
2 −−
−−
−−
−−
3 −−
−−
4.28
2.4
# Points −− 179 −− −− −− 545
# Labs 3 3

Mean −− 27.80 −− −− −− 165.3
SD
CV
1 −−
−−
0.942
3.4
2 −−
−−
−−
−−
3 −−
−−
3.16
1.9
# Points −− 298 −− −− −− 316
# Labs 1 1

Mean −− 26.85 −− −− −− 172.7
SD
CV
1 −−
−−
1.72
6.4
2 −−
−−
−−
−−
3 −−
−−
6.89
4.0
# Points −− 477 −− −− −− 861
# Labs 4 4

Mean −− 27.12 −− −− −− 173.8
SD
CV
1 −−
−−
2.59
9.5
2 −−
−−
−−
−−
3 −−
−−
47.20
27.2
# Points −− 75 −− −− −− 73
# Labs 1 1

Mean −− 22.74 −− −− −− 173.1
SD
CV
1 −−
−−
1.15
5.1
2 −−
−−
−−
−−
3 −−
−−
2.52
1.5
# Points −− 31 −− −− −− 162
# Labs 1 1

Mean 20.09 22.81 71.03 79.61 147.2 169.4
SD
CV
1 0.785
3.9
2.48
10.9
2 1.26
1.8
6.57
8.3
3 2.37
1.6
12.32
7.3
# Points 62 1777 63 1935 59 2953
# Labs 2 6 2 7 2 11

Mean 26.33 25.50 89.40 83.27 −− 164.5
SD
CV
1 0.816
3.1
1.60
6.3
2 1.52
1.7
4.13
5.0
3 −−
−−
7.28
4.4
# Points 6 554 5 504 −− 339
# Labs 1 5 1 5 2


Fuji Dri−Chem Series • Fuji Dri−Chem GPT/ALT−PIII, REF 9903150
Mean 26.00 25.32 82.00 81.94 −− −−
SD
CV
1 0.000
0.0
0.726
2.9
2
0.000
0.0
2.07
2.5
3 −−
−−
−−
−−
# Points 1 47 1 48 −− −−
# Labs 1 2 1 3
Mindray BS Series
Mean −− 26.25 −− 184.9 −− −−
SD
CV
1 −−
−−
0.510
1.9
2 −−
−−
3.68
2.0
3 −−
−−
−−
−−
# Points −− 217 −− 223 −− −−
# Labs 1 1

Mean 22.13 22.27 −− −− 165.5 167.0
SD
CV
1 0.925
4.2
0.810
3.6
2 −−
−−
−−
−−
3 5.12
3.1
3.62
2.2
# Points 71 748 −− −− 71 628
# Labs 2 2 2 2

Mean 21.16 22.41 78.70 82.54 165.4 173.5
SD
CV
1 0.690
3.3
1.16
5.2
2 1.00
1.3
2.61
3.2
3 2.18
1.3
6.17
3.6
# Points 14 268 14 268 14 268
# Labs 1 1 1 1 1 1

Mean −− 27.66 −− 95.90 −− 197.8
SD
CV
1 −−
−−
1.75
6.3
2 −−
−−
1.70
1.8
3 −−
−−
4.16
2.1
# Points −− 767 −− 325 −− 780
# Labs 3 2 3

Mean −− 23.73 −− 81.72 −− 168.1
SD
CV
1 −−
−−
0.870
3.7
2 −−
−−
1.23
1.5
3 −−
−−
3.73
2.2
# Points −− 55 −− 54 −− 54
# Labs 1 1 1

Mean 21.41 24.12 73.56 89.03 158.0 173.4
SD
CV
1 1.66
7.7
2.78
11.5
2 5.20
7.1
26.55
29.8
3 9.88
6.3
15.28
8.8
# Points 154 4539 83 3357 144 5257
# Labs 7 23 5 20 5 22
ALT (ALAT/GPT) Enzymatic, fluorescence U/L @ 37° C

Mean −− 23.50 −− −− −− 176.5
SD
CV
1 −−
−−
0.570
2.4
2 −−
−−
−−
−−
3 −−
−−
2.64
1.5
# Points −− 436 −− −− −− 432
# Labs 1 1
Method Group • Enzymatic, fluorescence

Mean −− 23.50 −− −− −− 176.5
SD
CV
1 −−
−−
0.570
2.4
2 −−
−−
−−
−−
3 −−
−−
2.64
1.5
# Points −− 436 −− −− −− 432
# Labs 1 1

ALT (ALAT/GPT) Enzymatic, fluorescence U/L @ 4° C

Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH ALT2 REF 04S88
Mean 22.27 22.21 80.27 80.21 −− −−
SD
CV
1 0.458
2.1
0.419
1.9
2
0.458
0.6
0.535
0.7
3 −−
−−
−−
−−
# Points 15 19 15 19 −− −−
# Labs 1 1 1 1
Method Group • Enzymatic, fluorescence

Mean 22.27 22.21 80.27 80.21 −− −−
SD
CV
1 0.458
2.1
0.419
1.9
2 0.458
0.6
0.535
0.7
3 −−
−−
−−
−−
# Points 15 19 15 19 −− −−
# Labs 1 1 1 1
ALT (ALAT/GPT) Other NADH depletion U/L @ 25° C

Mean −− 21.89 −− 74.54 −− 156.1
SD
CV
1 −−
−−
0.994
4.5
2 −−
−−
1.32
1.8
3 −−
−−
2.59
1.7
# Points −− 37 −− 37 −− 37
# Labs 1 1 1

Mean −− 22.56 −− −− −− 172.6
SD
CV
1 −−
−−
0.912
4.0
2 −−
−−
−−
−−
3 −−
−−
4.11
2.4
# Points −− 1280 −− −− −− 1239
# Labs 2 2
Roche cobas c 303/503 • Roche ALTP, REF 08056773

Mean 21.38 22.23 −− −− 169.9 171.6
SD
CV
1 0.993
4.6
1.01
4.5
2 −−
−−
−−
−−
3 2.74
1.6
3.82
2.2
# Points 100 2146 −− −− 96 2093
# Labs 2 2 2 2
Method Group • Other NADH depletion

Mean 21.38 22.23 −− 74.54 169.9 171.3
SD
CV
1 0.993
4.6
1.01
4.5
2 −−
−−
1.32
1.8
3 2.74
1.6
4.31
2.5
# Points 100 2183 −− 37 96 2130
# Labs 2 3 1 2 3

Mean 23.38 24.46 80.71 83.91 168.3 173.3
SD
CV
1 1.37
5.9
2.62
10.7
2 2.11
2.6
2.92
3.5
3 3.27
1.9
4.50
2.6
# Points 45 1131 45 1101 43 1038
# Labs 2 4 2 4 2 4

Mean 20.78 20.77 −− −− 152.5 152.5
SD
CV
1 0.659
3.2
0.661
3.2
2 −−
−−
−−
−−
3 2.01
1.3
2.49
1.6
# Points 63 498 −− −− 63 500
# Labs 2 2 2 2
ERBA XL−640
Mean −− 20.94 −− 76.96 −− −−
SD
CV
1 −−
−−
0.681
3.3
2 −−
−−
2.26
2.9
3 −−
−−
−−
−−
# Points −− 57 −− 57 −− −−
# Labs 1 1


Mean −− 24.55 −− −− −− −−
SD
CV
1 −−
−−
0.638
2.6
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 65 −− −− −− −−
# Labs 1

Mean 23.80 23.93 85.55 85.16 −− −−
SD
CV
1 1.12
4.7
0.850
3.6
2 3.02
3.5
2.74
3.2
3 −−
−−
−−
−−
# Points 28 68 28 68 −− −−
# Labs 1 1 1 1

Mean −− 29.19 −− 98.02 −− 203.0
SD
CV
1 −−
−−
1.53
5.2
2 −−
−−
2.22
2.3
3 −−
−−
4.20
2.1
# Points −− 5913 −− 5842 −− 5834
# Labs 4 4 4

Mean 22.26 27.81 82.57 95.53 158.9 195.4
SD
CV
1 1.73
7.8
3.11
11.2
2 3.43
4.2
5.96
6.2
3 8.19
5.2
16.02
8.2
# Points 136 7732 73 7068 106 7372
# Labs 5 13 3 10 4 10
ALT (ALAT/GPT) UV with P5P U/L @ 25° C

Mean −− 22.08 −− −− −− 156.3
SD
CV
1 −−
−−
0.515
2.3
2 −−
−−
−−
−−
3 −−
−−
3.28
2.1
# Points −− 12 −− −− −− 12
# Labs 2 2

Mean −− 25.26 −− 89.75 −− −−
SD
CV
1 −−
−−
1.37
5.4
2 −−
−−
2.51
2.8
3 −−
−−
−−
−−
# Points −− 50 −− 26 −− −−
# Labs 1 1
Method Group • UV with P5P

Mean −− 24.64 −− 89.75 −− 156.3
SD
CV
1 −−
−−
1.78
7.2
2 −−
−−
2.51
2.8
3 −−
−−
3.28
2.1
# Points −− 62 −− 26 −− 12
# Labs 3 1 2

Mean −− 23.78 −− 83.22 −− 181.7
SD
CV
1 −−
−−
0.966
4.1
2 −−
−−
2.23
2.7
3 −−
−−
6.50
3.6
# Points −− 51 −− 286 −− 288
# Labs 1 3 3

Mean −− 18.09 81.63 84.26 174.5 180.2
SD
CV
1 −−
−−
0.943
5.2
2
0.920
1.1
2.03
2.4
3 2.20
1.3
3.77
2.1
# Points −− 486 8 1086 8 991
# Labs 2 1 4 1 3


Mean −− 21.96 −− 80.25 −− 165.4
SD
CV
1 −−
−−
1.33
6.1
2 −−
−−
5.49
6.8
3 −−
−−
12.39
7.5
# Points −− 3079 −− 3095 −− 3840
# Labs 10 11 14

Mean −− 26.03 −− 85.25 −− 177.7
SD
CV
1 −−
−−
0.907
3.5
2 −−
−−
1.50
1.8
3 −−
−−
2.99
1.7
# Points −− 655 −− 653 −− 652
# Labs 1 1 1

Mean −− 23.42 −− 80.40 −− 168.3
SD
CV
1 −−
−−
1.02
4.3
2 −−
−−
2.53
3.1
3 −−
−−
5.21
3.1
# Points −− 204 −− 204 −− 203
# Labs 1 1 1

Mean −− 28.00 −− −− −− 191.0
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− 1 −− −− −− 1
# Labs 1 1

Mean −− −− −− 81.00 −− 162.0
SD
CV
1 −−
−−
−−
−−
2 −−
−−
8.27
10.2
3 −−
−−
16.67
10.3
# Points −− −− −− 108 −− 107
# Labs 1 1
RANDOX RX daytona
Mean 27.33 25.89 89.50 89.85 194.0 194.0
SD
CV
1 4.19
15.3
4.14
16.0
2 8.33
9.3
8.99
10.0
3 0.000
0.0
0.000
0.0
# Points 20 134 16 113 1 1
# Labs 1 1 1 1 1 1
RANDOX RX imola
Mean 25.88 25.38 90.72 87.38 −− −−
SD
CV
1 0.719
2.8
0.792
3.1
2 2.08
2.3
3.36
3.8
3 −−
−−
−−
−−
# Points 26 225 24 192 −− −−
# Labs 1 1 1 1

Mean −− 22.72 −− 81.20 −− 170.2
SD
CV
1 −−
−−
1.46
6.4
2 −−
−−
2.46
3.0
3 −−
−−
4.56
2.7
# Points −− 3815 −− 3219 −− 3557
# Labs 10 7 10
Roche cobas 6000/8000/c 311 • Factored, IFCC Correlated

Mean −− 23.65 −− −− −− 175.4
SD
CV
1 −−
−−
0.919
3.9
2 −−
−−
−−
−−
3 −−
−−
2.85
1.6
# Points −− 156 −− −− −− 155
# Labs 3 3

Mean 21.59 22.35 80.50 80.85 167.4 168.5
SD
CV
1 0.712
3.3
0.970
4.3
2 2.10
2.6
1.87
2.3
3 3.17
1.9
3.40
2.0
# Points 60 918 71 1048 51 774
# Labs 2 2 2 2 2 2


Mean −− 22.61 −− −− −− 169.7
SD
CV
1 −−
−−
0.931
4.1
2 −−
−−
−−
−−
3 −−
−−
6.14
3.6
# Points −− 434 −− −− −− 435
# Labs 2 2

Mean −− 24.77 −− 88.58 −− 186.7
SD
CV
1 −−
−−
1.12
4.5
2 −−
−−
1.92
2.2
3 −−
−−
3.45
1.8
# Points −− 629 −− 601 −− 600
# Labs 2 2 2

Mean −− 27.43 −− 97.07 −− 200.7
SD
CV
1 −−
−−
1.79
6.5
2 −−
−−
3.77
3.9
3 −−
−−
7.80
3.9
# Points −− 426 −− 882 −− 705
# Labs 4 4 4

Mean −− 24.95 −− −− −− 182.7
SD
CV
1 −−
−−
1.21
4.9
2 −−
−−
−−
−−
3 −−
−−
2.97
1.6
# Points −− 1372 −− −− −− 1354
# Labs 7 7

Mean 26.61 27.11 −− 89.91 175.6 182.7
SD
CV
1 1.96
7.4
3.10
11.4
2 −−
−−
4.54
5.1
3 4.97
2.8
7.16
3.9
# Points 176 25416 −− 3863 176 22519
# Labs 6 55 12 6 52

Mean −− 28.55 −− 91.26 −− 187.4
SD
CV
1 −−
−−
1.33
4.7
−−
−−
2 9.32
10.2
3 −−
−−
2.20
1.2
# Points −− 42 −− 50 −− 21
# Labs 1 1 1

Mean 24.44 27.08 83.16 88.97 171.6 179.8
SD
CV
1 2.05
8.4
2.26
8.4
2 2.46
3.0
3.55
4.0
3 4.52
2.6
5.86
3.3
# Points 747 57888 238 16710 638 53985
# Labs 17 110 5 28 17 106

Mean −− 24.26 −− 84.08 −− 178.1
SD
CV
1 −−
−−
1.45
6.0
2 −−
−−
3.84
4.6
3 −−
−−
5.72
3.2
# Points −− 98 −− 107 −− 107
# Labs 1 1 1

Mean 24.74 26.56 83.39 87.05 172.2 179.6
SD
CV
1 2.34
9.5
2.84
10.7
2 3.90
4.7
5.43
6.2
3 5.00
2.9
7.90
4.4
# Points 1029 95985 357 32059 874 90165
# Labs 27 214 10 78 27 213
ALT (ALAT/GPT) UV with P5P − IFCC Ref. Proc., Calibrated U/L @ 25° C
Mean −− 26.98 −− 93.81 −− 194.7
SD
CV
1 −−
−−
1.36
5.1
2 −−
−−
2.46
2.6
3 −−
−−
4.71
2.4
# Points −− 904 −− 946 −− 936
# Labs 1 1 1

Mean −− 20.64 −− −− −− 165.2
SD
CV
1 −−
−−
0.575
2.8
2 −−
−−
−−
−−
3 −−
−−
3.69
2.2
# Points −− 187 −− −− −− 177
# Labs 1 1

Mean −− 21.42 −− −− −− 166.1
SD
CV
1 −−
−−
0.815
3.8
2 −−
−−
−−
−−
3 −−
−−
3.70
2.2
# Points −− 130 −− −− −− 133
# Labs 1 1

Mean −− 21.07 −− −− −− 164.0
SD
CV
1 −−
−−
0.562
2.7
2 −−
−−
−−
−−
3 −−
−−
16.76
10.2
# Points −− 105 −− −− −− 101
# Labs 1 1
Method Group • UV with P5P − IFCC Ref. Proc., Calibrated

Mean −− 25.07 −− 93.81 −− 185.7
SD
CV
1 −−
−−
3.04
12.1
2 −−
−−
2.46
2.6
3 −−
−−
14.99
8.1
# Points −− 1326 −− 946 −− 1347
# Labs 4 1 4
Mean 21.96 18.76 79.46 84.53 −− 182.1
SD
CV
1 0.916
4.2
1.29
6.9
2 1.61
2.0
2.49
2.9
3 −−
−−
4.33
2.4
# Points 26 8505 26 8102 −− 8448
# Labs 1 16 1 15 14
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH ALT2, REF 04S88 (Factored, IFCC Correlated)
Mean 22.76 23.18 83.59 83.92 −− −−
SD
CV
1 1.65
7.2
1.90
8.2
2
6.23
7.5
6.83
8.1
3 −−
−−
−−
−−
# Points 79 213 73 210 −− −−
# Labs 4 4 4 4
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c ALT2, REF 04T84 (Factored, IFCC Correlated)
Mean 22.75 22.27 79.00 83.28 159.8 180.4
SD
CV
1 0.500
2.2
2.08
9.3
2 0.000
0.0
2.06
2.5
3 1.50
0.9
5.76
3.2
# Points 4 95 4 94 4 79
# Labs 1 3 1 3 1 3

Mean 21.22 19.77 80.06 84.82 −− 181.3
SD
CV
1 1.79
8.4
2.47
12.5
2 1.51
1.9
2.53
3.0
3 −−
−−
6.63
3.7
# Points 36 6359 18 4040 −− 6429
# Labs 3 17 2 11 13

Mean 23.12 23.51 81.96 84.56 173.1 174.2
SD
CV
1 0.981
4.2
1.64
7.0
2 1.80
2.2
2.77
3.3
3 3.05
1.8
9.46
5.4
# Points 164 7375 142 7417 160 8426
# Labs 3 23 2 17 3 26

Mean −− 24.72 −− −− −− −−
SD
CV
1 −−
−−
0.882
3.6
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 36 −− −− −− −−
# Labs 1

Mindray BS Series
Mean −− 29.02 −− 91.85 −− 192.3
SD
CV
1 −−
−−
1.42
4.9
2 −−
−−
1.71
1.9
3 −−
−−
3.73
1.9
# Points −− 90 −− 327 −− 327
# Labs 1 1 1

Mean −− −− −− 86.31 −− 181.4
SD
CV
1 −−
−−
−−
−−
2 −−
−−
6.36
7.4
3 −−
−−
13.31
7.3
# Points −− −− −− 190 −− 191
# Labs 1 1

Mean 22.95 23.12 −− 82.66 171.2 171.7
SD
CV
1 1.27
5.5
1.44
6.2
2 −−
−−
3.65
4.4
3 3.03
1.8
4.49
2.6
# Points 878 17276 −− 1266 872 17513
# Labs 13 32 11 13 32

Mean 22.35 23.05 80.94 81.68 165.1 169.8
SD
CV
1 1.25
5.6
1.33
5.8
2
1.96
2.4
2.55
3.1
3 5.71
3.5
5.30
3.1
# Points 1265 28768 182 9136 1250 28803
# Labs 24 63 5 22 23 64

Mean 21.63 22.56 79.86 83.14 170.1 173.5
SD
CV
1 1.07
4.9
1.26
5.6
2 1.48
1.9
2.32
2.8
3 3.80
2.2
4.86
2.8
# Points 186 6958 72 4966 147 6629
# Labs 6 14 2 7 5 13
Roche cobas c 303/503 • Factored, IFCC Correlated

Mean −− 24.08 −− 85.70 −− 179.4
SD
CV
1 −−
−−
1.06
4.4
2 −−
−−
1.10
1.3
3 −−
−−
2.10
1.2
# Points −− 607 −− 560 −− 565
# Labs 4 2 3
Roche cobas c 303/503 • Roche ALTP, REF 08056773

Mean 22.32 22.32 78.98 81.71 169.3 170.8
SD
CV
1 1.13
5.1
1.08
4.8
2 1.97
2.5
2.12
2.6
3 2.66
1.6
5.60
3.3
# Points 249 7392 53 714 101 7286
# Labs 6 25 2 4 3 22
Roche cobas c 303/503 • Roche ALTP2, REF 08104697

Mean 21.64 23.15 −− −− 168.9 175.3
SD
CV
1 1.04
4.8
1.10
4.8
2 −−
−−
−−
−−
3 1.31
0.8
3.89
2.2
# Points 20 1152 −− −− 21 1113
# Labs 1 5 1 5

Mean 22.80 23.52 79.20 81.96 −− −−
SD
CV
1 1.20
5.3
1.30
5.5
2 1.20
1.5
1.97
2.4
3 −−
−−
−−
−−
# Points 98 1157 102 1187 −− −−
# Labs 1 1 1 1

Mean −− 23.02 −− −− −− 173.2
SD
CV
1 −−
−−
0.652
2.8
2 −−
−−
−−
−−
3 −−
−−
1.57
0.9
# Points −− 36 −− −− −− 36
# Labs 1 1

Roche cobas Integra / c 111 • Factored, IFCC Correlated
Mean 21.47 21.86 −− −− 160.4 165.1
SD
CV
1 0.580
2.7
0.929
4.3
2 −−
−−
−−
−−
3 2.82
1.8
5.47
3.3
# Points 40 1484 −− −− 39 1482
# Labs 1 4 1 4

Mean −− −− −− 86.07 −− 181.3
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.90
2.2
3 −−
−−
3.45
1.9
# Points −− −− −− 342 −− 342
# Labs 1 1
Mean −− −− −− 94.02 −− 198.8
SD
CV
1 −−
−−
−−
−−
2 −−
−−
7.08
7.5
3 −−
−−
17.27
8.7
# Points −− −− −− 93 −− 86
# Labs 3 1

Mean 33.14 27.22 95.91 94.55 −− 193.1
SD
CV
1 1.78
5.4
2.44
9.0
2 2.11
2.2
5.70
6.0
3 −−
−−
11.15
5.8
# Points 22 977 22 1901 −− 1883
# Labs 1 6 1 7 5
Siemens ADVIA Chemistry Systems • Factored, IFCC Correlated

Mean 29.73 27.81 92.91 93.06 −− 191.2
SD
CV
1 1.37
4.6
1.85
6.6
2
2.42
2.6
2.49
2.7
3 −−
−−
3.47
1.8
# Points 37 469 68 557 −− 96
# Labs 1 3 2 3 1

Mean 25.08 26.77 92.00 93.00 185.0 191.5
SD
CV
1 1.70
6.8
2.09
7.8
2 5.24
5.7
3.84
4.1
3 7.67
4.1
8.44
4.4
# Points 200 15499 56 5985 207 13311
# Labs 6 42 2 26 6 38
Siemens Atellica CH Analyzer • Factored, IFCC Correlated

Mean −− 26.77 −− 93.14 −− 197.3
SD
CV
1 −−
−−
1.30
4.8
2 −−
−−
2.55
2.7
3 −−
−−
3.34
1.7
# Points −− 5742 −− 5165 −− 954
# Labs 10 7 4
Siemens Atellica CH Analyzer • Siemens Atellica CH ALT, REF 11097605 (Factored, IFCC Correlated)
Mean 25.32 26.83 91.74 92.28 −− 196.3
SD
CV
1 1.09
4.3
1.67
6.2
2
1.48
1.6
2.28
2.5
3 −−
−−
6.11
3.1
# Points 341 5662 337 2050 −− 4165
# Labs 9 25 9 17 15
Siemens Atellica CH Analyzer • Siemens Atellica CH ALTPLc, REF 11097638

Mean −− 26.49 90.25 93.03 183.2 189.0
SD
CV
1 −−
−−
1.26
4.8
2
1.16
1.3
1.58
1.7
3 5.87
3.2
6.14
3.2
# Points −− 678 8 65 8 617
# Labs 6 1 3 1 5

Mean 26.99 27.08 85.57 88.82 175.3 182.2
SD
CV
1 2.43
9.0
3.21
11.9
2 3.13
3.7
4.04
4.5
3 5.74
3.3
6.97
3.8
# Points 1455 77474 381 15074 1288 71557
# Labs 49 208 15 53 42 185

Mean −− 28.35 −− 90.53 −− 183.9
SD
CV
1 −−
−−
1.97
7.0
2
−−
−−
2.58
2.8
3 −−
−−
5.10
2.8
# Points −− 251 −− 237 −− 248
# Labs 1 1 1

Mean 24.38 27.06 84.74 88.95 172.1 179.4
SD
CV
1 2.32
9.5
2.15
8.0
2 3.17
3.7
3.22
3.6
3 3.35
1.9
5.51
3.1
# Points 2673 195K 862 60873 2235 176K
# Labs 74 373 27 117 62 351

Mean −− −− 92.45 93.26 −− −−
SD
CV
1 −−
−−
−−
−−
2 3.42
3.7
3.47
3.7
3 −−
−−
−−
−−
# Points −− −− 18 26 −− −−
# Labs 1 1

Mean −− 23.83 −− 82.01 −− 170.7
SD
CV
1 −−
−−
5.13
21.5
2 −−
−−
5.42
6.6
3 −−
−−
7.75
4.5
# Points −− 698 −− 75 −− 765
# Labs 7 1 8

Mean −− 21.83 −− 89.95 −− 176.5
SD
CV
1 −−
−−
1.46
6.7
2 −−
−−
5.22
5.8
3 −−
−−
7.67
4.3
# Points −− 561 −− 390 −− 951
# Labs 3 1 4

Mean −− 29.66 −− −− −− 180.0
SD
CV
1 −−
−−
10.15
34.2
2 −−
−−
−−
−−
3 −−
−−
5.58
3.1
# Points −− 125 −− −− −− 121
# Labs 1 1

Mean −− 20.97 −− 85.75 −− 172.5
SD
CV
1 −−
−−
0.738
3.5
2 −−
−−
7.05
8.2
3 −−
−−
6.28
3.6
# Points −− 432 −− 159 −− 643
# Labs 3 3 3

Mean −− 21.67 −− 81.95 −− 170.3
SD
CV
1 −−
−−
1.12
5.2
2 −−
−−
3.83
4.7
3 −−
−−
6.36
3.7
# Points −− 12382 −− 4779 −− 11664
# Labs 76 29 74

Mean −− 21.64 −− 82.25 −− 167.9
SD
CV
1 −−
−−
0.968
4.5
2 −−
−−
2.28
2.8
3 −−
−−
5.22
3.1
# Points −− 9288 −− 2944 −− 8881
# Labs 66 21 64

Mean 24.25 24.16 83.59 83.15 166.1 169.4
SD
CV
1 1.10
4.6
1.01
4.2
2 4.19
5.0
2.79
3.4
3 8.61
5.2
6.22
3.7
# Points 213 7558 128 2962 205 7596
# Labs 9 56 5 16 8 50

Mean 23.58 23.88 82.64 82.21 168.2 168.0
SD
CV
1 1.07
4.5
1.08
4.5
2 2.12
2.6
3.23
3.9
3 6.35
3.8
5.50
3.3
# Points 198 12251 78 4947 174 11933
# Labs 8 70 2 26 7 59

Mean 23.67 23.50 85.96 85.44 176.3 175.0
SD
CV
1 1.05
4.4
1.12
4.8
2 2.87
3.3
2.88
3.4
3 7.12
4.0
6.47
3.7
# Points 306 1130 139 547 310 1133
# Labs 12 20 6 10 13 19

Mean 26.22 20.77 82.45 82.42 176.4 172.5
SD
CV
1 3.34
12.7
4.07
19.6
2 1.73
2.1
1.77
2.1
3 6.65
3.8
4.79
2.8
# Points 98 434 31 40 95 423
# Labs 8 10 1 1 8 10

Mean −− 19.56 −− 77.21 −− 158.5
SD
CV
1 −−
−−
0.919
4.7
2 −−
−−
1.65
2.1
3 −−
−−
4.17
2.6
# Points −− 1259 −− 985 −− 1223
# Labs 15 12 15

Mean −− 20.64 −− 78.49 −− 168.1
SD
CV
1 −−
−−
1.09
5.3
2 −−
−−
3.74
4.8
3 −−
−−
7.50
4.5
# Points −− 1797 −− 990 −− 1804
# Labs 15 10 15

Mean −− 19.92 −− 77.95 −− 160.5
SD
CV
1 −−
−−
0.809
4.1
2 −−
−−
2.03
2.6
3 −−
−−
4.57
2.8
# Points −− 2465 −− 2052 −− 2482
# Labs 19 15 19

Mean 21.93 21.90 80.83 79.89 169.1 169.8
SD
CV
1 0.675
3.1
0.998
4.6
2 1.60
2.0
1.80
2.3
3 4.36
2.6
5.15
3.0
# Points 59 1452 28 598 59 1445
# Labs 2 10 1 8 2 11

Mean −− 22.09 −− 78.77 −− 164.7
SD
CV
1 −−
−−
0.706
3.2
2 −−
−−
2.08
2.6
3 −−
−−
4.79
2.9
# Points −− 1158 −− 683 −− 1158
# Labs 8 5 8

Mean 23.29 22.25 80.68 81.07 164.3 163.8
SD
CV
1 0.780
3.3
1.39
6.3
2 2.10
2.6
1.88
2.3
3 4.09
2.5
6.58
4.0
# Points 147 1137 82 201 109 1112
# Labs 6 8 4 4 6 8

Mean 21.21 21.21 79.48 79.48 167.0 167.0
SD
CV
1 0.502
2.4
0.502
2.4
2 1.59
2.0
1.59
2.0
3 2.79
1.7
2.79
1.7
# Points 17 17 16 16 15 15
# Labs 2 2 2 2 2 2

Mean −− 49.37 −− −− −− 210.4
SD
CV
1 −−
−−
2.06
4.2
2 −−
−−
−−
−−
3 −−
−−
3.96
1.9
# Points −− 79 −− −− −− 78
# Labs 1 1

Mean −− 47.13 −− −− −− 199.3
SD
CV
1 −−
−−
2.30
4.9
2 −−
−−
−−
−−
3 −−
−−
4.09
2.1
# Points −− 59 −− −− −− 53
# Labs 1 1

Mean −− 42.06 −− −− −− 190.8
SD
CV
1 −−
−−
1.94
4.6
2 −−
−−
−−
−−
3 −−
−−
4.45
2.3
# Points −− 97 −− −− −− 97
# Labs 1 1

Mean −− 43.65 −− −− −− 199.4
SD
CV
1 −−
−−
2.03
4.6
2 −−
−−
−−
−−
3 −−
−−
3.19
1.6
# Points −− 71 −− −− −− 69
# Labs 1 1

Mean −− 45.55 −− −− −− 201.8
SD
CV
1 −−
−−
2.01
4.4
2 −−
−−
−−
−−
3 −−
−−
4.11
2.0
# Points −− 120 −− −− −− 120
# Labs 1 1

Mean 22.46 25.20 78.05 79.24 −− 193.2
SD
CV
1 0.679
3.0
5.68
22.6
2 2.08
2.7
2.32
2.9
3 −−
−−
4.14
2.1
# Points 75 791 77 692 −− 97
# Labs 2 3 2 2 1

Mean −− 41.21 −− −− −− 190.7
SD
CV
1 −−
−−
2.41
5.9
2 −−
−−
−−
−−
3 −−
−−
4.82
2.5
# Points −− 259 −− −− −− 268
# Labs 1 1

Mean −− 23.07 −− −− −− 162.7
SD
CV
1 −−
−−
0.662
2.9
2 −−
−−
−−
−−
3 −−
−−
5.67
3.5
# Points −− 130 −− −− −− 132
# Labs 2 2
VITROS Microtip Series

Mean −− −− −− 83.01 −− 169.8
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.96
2.4
3 −−
−−
4.64
2.7
# Points −− −− −− 968 −− 943
# Labs 3 3

Mean −− 23.81 −− −− −− 166.2
SD
CV
1 −−
−−
0.872
3.7
2 −−
−−
−−
−−
3 −−
−−
3.57
2.1
# Points −− 130 −− −− −− 134
# Labs 1 1

Mean 24.18 25.58 84.80 86.86 171.4 177.9
SD
CV
1 2.52
10.4
3.26
12.8
2
4.86
5.7
4.98
5.7
3 6.60
3.8
8.65
4.9
# Points 8886 445K 3003 155K 7299 412K
# Labs 253 1288 101 509 207 1190
ALT (ALAT/GPT) UV with P5P−VITROS U/L @ 37° C

Mean −− 27.00 −− 95.30 −− 195.5
SD
CV
1 −−
−−
0.700
2.6
2 −−
−−
1.40
1.5
3 −−
−−
1.70
0.9
# Points −− 12 −− 12 −− 12
# Labs 1 1 1

Mean 22.80 24.31 79.33 84.41 163.2 169.9
SD
CV
1 1.00
4.4
4.71
19.4
2 1.53
1.9
10.01
11.9
3 1.90
1.2
9.96
5.9
# Points 14 1321 3 1120 15 1089
# Labs 1 12 1 12 1 7

Mean −− 20.91 −− −− −− 164.2
SD
CV
1 −−
−−
0.512
2.4
2 −−
−−
−−
−−
3 −−
−−
4.22
2.6
# Points −− 328 −− −− −− 365
# Labs 3 4

Mean −− 25.93 −− 90.56 −− 176.5
SD
CV
1 −−
−−
7.26
28.0
2 −−
−−
3.67
4.1
3 −−
−−
7.48
4.2
# Points −− 816 −− 95 −− 817
# Labs 3 1 3

Mean −− 25.57 −− −− −− 173.9
SD
CV
1 −−
−−
7.31
28.6
2 −−
−−
−−
−−
3 −−
−−
8.27
4.8
# Points −− 340 −− −− −− 325
# Labs 5 5

Mean 22.24 21.83 77.95 80.96 159.0 171.9
SD
CV
1 0.996
4.5
1.15
5.3
2 3.06
3.9
4.36
5.4
3 4.36
2.7
6.86
4.0
# Points 17 2845 22 838 21 2789
# Labs 1 19 1 5 1 17

Mean −− 20.96 −− 80.35 −− 165.0
SD
CV
1 −−
−−
0.938
4.5
2 −−
−−
2.17
2.7
3 −−
−−
6.33
3.8
# Points −− 2083 −− 926 −− 1881
# Labs 15 5 15

Mean 24.06 24.08 78.33 80.77 172.0 166.0
SD
CV
1 1.17
4.8
0.975
4.1
2 1.21
1.5
3.14
3.9
3 7.74
4.5
5.09
3.1
# Points 25 1393 4 630 26 1088
# Labs 2 19 1 9 2 14

Mean 24.09 23.91 77.70 81.24 175.0 169.4
SD
CV
1 1.07
4.4
1.05
4.4
2 2.51
3.2
3.58
4.4
3 2.70
1.5
5.97
3.5
# Points 65 3502 34 1370 31 2627
# Labs 3 26 2 14 1 17


Mean 23.01 23.30 84.31 84.22 172.5 175.2
SD
CV
1 0.926
4.0
1.13
4.8
2 1.45
1.7
1.51
1.8
3 4.59
2.7
5.06
2.9
# Points 135 386 97 246 88 261
# Labs 7 8 4 5 5 5

Mean 21.38 21.42 −− 85.18 163.2 163.4
SD
CV
1 0.711
3.3
0.733
3.4
2 −−
−−
1.24
1.5
3 3.07
1.9
3.21
2.0
# Points 41 42 −− 2 42 43
# Labs 2 3 1 2 3

Mean −− 19.70 −− −− −− 161.9
SD
CV
1 −−
−−
1.37
6.9
2 −−
−−
−−
−−
3 −−
−−
10.13
6.3
# Points −− 304 −− −− −− 300
# Labs 3 3

Mean −− 20.93 −− −− −− 165.1
SD
CV
1 −−
−−
1.92
9.2
2 −−
−−
−−
−−
3 −−
−−
6.70
4.1
# Points −− 498 −− −− −− 495
# Labs 4 4

Mean −− 20.12 −− 79.05 −− 161.9
SD
CV
1 −−
−−
0.888
4.4
2 −−
−−
2.39
3.0
3 −−
−−
6.92
4.3
# Points −− 652 −− 77 −− 663
# Labs 4 1 4

Mean 22.26 21.78 −− 82.62 169.7 169.0
SD
CV
1 0.737
3.3
1.06
4.9
2 −−
−−
0.854
1.0
3 3.24
1.9
5.05
3.0
# Points 27 909 −− 5 22 839
# Labs 1 5 2 1 5

Mean −− 21.41 −− 81.95 −− 165.0
SD
CV
1 −−
−−
1.65
7.7
2 −−
−−
2.59
3.2
3 −−
−−
5.45
3.3
# Points −− 907 −− 155 −− 724
# Labs 4 1 3

Mean 21.60 21.98 −− 79.95 152.7 153.7
SD
CV
1 1.12
5.2
1.09
5.0
2 −−
−−
11.36
14.2
3 9.29
6.1
9.35
6.1
# Points 67 242 −− 85 66 157
# Labs 3 4 1 3 3

Mean 22.53 22.46 81.18 81.11 −− −−
SD
CV
1 0.813
3.6
0.805
3.6
2 2.26
2.8
2.21
2.7
3 −−
−−
−−
−−
# Points 34 38 32 36 −− −−
# Labs 1 1 1 1

Mean −− 38.99 −− −− −− 189.0
SD
CV
1 −−
−−
2.23
5.7
2 −−
−−
−−
−−
3 −−
−−
4.45
2.4
# Points −− 15 −− −− −− 15
# Labs 1 1


Mean −− 37.61 −− −− −− 178.9
SD
CV
1 −−
−−
3.10
8.2
2 −−
−−
−−
−−
3 −−
−−
5.48
3.1
# Points −− 11 −− −− −− 18
# Labs 1 1

Mean −− −− −− −− −− 149.3
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− −− −− −− −− 1
# Labs 1

Mean −− 34.14 −− −− −− 185.9
SD
CV
1 −−
−−
4.36
12.8
2 −−
−−
−−
−−
3 −−
−−
8.85
4.8
# Points −− 63 −− −− −− 76
# Labs 1 1

Mean −− −− −− 83.97 −− 171.0
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.41
1.7
3 −−
−−
3.53
2.1
# Points −− −− −− 357 −− 357
# Labs 1 1

Mean −− 38.10 −− −− −− 188.0
SD
CV
1 −−
−−
2.75
7.2
2 −−
−−
−−
−−
3 −−
−−
5.39
2.9
# Points −− 56 −− −− −− 54
# Labs 1 1

Mean −− 21.42 −− 88.28 −− 176.1
SD
CV
1 −−
−−
0.532
2.5
2 −−
−−
3.34
3.8
3 −−
−−
12.17
6.9
# Points −− 31414 −− 55 −− 145
# Labs 2 1 2

Mean −− 38.39 −− −− −− 185.9
SD
CV
1 −−
−−
4.25
11.1
2 −−
−−
−−
−−
3 −−
−−
7.73
4.2
# Points −− 61 −− −− −− 60
# Labs 1 1
Method Group • UV with P5P−VITROS

Mean 22.73 21.94 81.68 82.08 165.7 169.1
SD
CV
1 1.32
5.8
2.18
9.9
2 3.51
4.3
5.72
7.0
3 9.96
6.0
8.18
4.8
# Points 425 47748 192 5997 311 14733
# Labs 21 143 10 60 16 119
ALT (ALAT/GPT) UV without P5P U/L @ 22° C

Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH ALT REF 7D56
Mean −− 22.55 −− 81.21 −− −−
SD
CV
1 −−
−−
1.46
6.5
2−−
−−
1.81
2.2
3 −−
−−
−−
−−
# Points −− 150 −− 150 −− −−
# Labs 1 1

Mean 24.69 22.72 82.77 81.28 −− −−
SD
CV
1 0.480
1.9
1.49
6.6
2
0.599
0.7
1.81
2.2
3 −−
−−
−−
−−
# Points 13 170 13 170 −− −−
# Labs 1 1 1 1


Method Group • UV without P5P
Mean 24.69 22.72 82.77 81.28 −− −−
SD
CV
1 0.480
1.9
1.49
6.6
2 0.599
0.7
1.81
2.2
3 −−
−−
−−
−−
# Points 13 170 13 170 −− −−
# Labs 1 1 1 1

Mean 27.00 26.00 76.00 75.50 −− 150.0
SD
CV
1 0.000
0.0
2.10
8.1
2 0.000
0.0
2.58
3.4
3 −−
−−
5.57
3.7
# Points 1 25 1 22 −− 3
# Labs 1 1 1 1 1

Mean −− 25.48 −− −− −− 178.1
SD
CV
1 −−
−−
1.52
6.0
2 −−
−−
−−
−−
3 −−
−−
4.27
2.4
# Points −− 132 −− −− −− 135
# Labs 1 1

Mean −− 23.59 −− 76.55 −− 158.5
SD
CV
1 −−
−−
2.79
11.8
2 −−
−−
2.47
3.2
3 −−
−−
6.20
3.9
# Points −− 486 −− 132 −− 463
# Labs 4 2 4

Mean −− 24.72 −− −− −− 173.0
SD
CV
1 −−
−−
1.65
6.7
2 −−
−−
−−
−−
3 −−
−−
6.60
3.8
# Points −− 398 −− −− −− 399
# Labs 2 2
ILab Series
Mean 25.09 25.15 82.55 83.46 −− −−
SD
CV
1 1.04
4.2
0.850
3.4
2 2.11
2.6
2.05
2.5
3 −−
−−
−−
−−
# Points 11 48 11 48 −− −−
# Labs 1 1 1 1
Roche cobas 6000/8000/c 311 • Alternate Formulation/Standardization

Mean −− 23.47 −− −− −− 170.6
SD
CV
1 −−
−−
0.596
2.5
−−
−−
2 −−
−−
3 −−
−−
2.91
1.7
# Points −− 34 −− −− −− 34
# Labs 1 1

Mean 25.25 24.35 82.00 78.07 −− 166.9
SD
CV
1 1.14
4.5
2.33
9.6
2 2.76
3.4
3.85
4.9
3 −−
−−
10.12
6.1
# Points 12 1089 12 202 −− 1000
# Labs 2 9 2 4 8

Mean 21.00 21.17 −− −− 152.0 154.5
SD
CV
1 1.00
4.8
0.749
3.5
2 −−
−−
−−
−−
3 1.00
0.7
1.95
1.3
# Points 22 401 −− −− 22 401
# Labs 1 1 1 1


Mean 21.00 21.17 −− −− 152.0 154.5
SD
CV
1 1.00
4.8
0.749
3.5
2 −−
−−
−−
−−
3 1.00
0.7
1.95
1.3
# Points 22 401 −− −− 22 401
# Labs 1 1 1 1

Mean 23.37 24.36 81.53 83.36 171.4 175.2
SD
CV
1 1.40
6.0
1.74
7.2
2 3.43
4.2
3.13
3.8
3 5.68
3.3
5.65
3.2
# Points 1386 57115 905 28183 1032 54812
# Labs 43 179 31 107 28 148

Mean 22.78 22.71 80.29 80.70 −− −−
SD
CV
1 0.955
4.2
1.01
4.5
2
2.77
3.5
2.86
3.5
3 −−
−−
−−
−−
# Points 172 351 171 353 −− −−
# Labs 7 7 7 7
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH ALT2, REF 04S88 (Factored, IFCC Correlated)
Mean 23.57 22.94 82.65 81.11 174.1 170.5
SD
CV
1 1.24
5.3
1.46
6.4
2
3.13
3.8
3.94
4.9
3 9.37
5.4
8.74
5.1
# Points 149 2870 151 2686 31 2245
# Labs 8 11 8 10 5 7
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c A−ALT, REF 08P18 (Factored, IFCC Correlated)
Mean −− 22.23 −− 78.46 −− −−
SD
CV
1 −−
−−
1.12
5.0
2 −−
−−
1.88
2.4
3 −−
−−
−−
−−
# Points −− 74 −− 74 −− −−
# Labs 1 1
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c ALT, REF 07P98

Mean −− 24.53 −− 83.03 −− −−
SD
CV
1 −−
−−
9.31
38.0
2 −−
−−
7.62
9.2
3 −−
−−
−−
−−
# Points −− 88 −− 83 −− −−
# Labs 2 2
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c ALT2, REF 04T84 (Factored, IFCC Correlated)
Mean 21.69 22.25 77.73 77.68 160.6 166.4
SD
CV
1 0.820
3.8
1.28
5.8
2 1.33
1.7
2.58
3.3
3 3.18
2.0
7.13
4.3
# Points 68 652 69 232 84 775
# Labs 6 8 6 6 6 8

Mean 22.78 23.62 80.80 83.20 168.4 171.5
SD
CV
1 1.16
5.1
1.56
6.6
2 1.79
2.2
2.54
3.0
3 2.04
1.2
6.15
3.6
# Points 96 1165 25 555 91 1157
# Labs 4 6 2 4 3 5
Abbott ARCHITECT/Alinity (c, i, ci models) • Sekisui Pureauto

Mean −− 23.51 −− 82.13 −− 172.7
SD
CV
1 −−
−−
0.960
4.1
2 −−
−−
2.09
2.5
3 −−
−−
4.20
2.4
# Points −− 269 −− 269 −− 270
# Labs 1 1 1

Mean 23.43 23.93 85.72 86.52 181.9 181.8
SD
CV
1 0.480
2.0
0.784
3.3
2 0.430
0.5
1.68
1.9
3 1.12
0.6
2.83
1.6
# Points 15 378 15 411 15 407
# Labs 1 1 1 1 1 1


Mean −− −− −− 81.51 −− 172.7
SD
CV
1 −−
−−
−−
−−
2 −−
−−
3.41
4.2
3 −−
−−
6.63
3.8
# Points −− −− −− 574 −− 569
# Labs 2 2

Mean 20.67 21.64 73.38 74.75 150.7 154.5
SD
CV
1 1.09
5.3
1.70
7.9
2 3.45
4.7
3.36
4.5
3 4.53
3.0
5.66
3.7
# Points 1757 72040 1413 36489 643 55338
# Labs 60 212 49 118 23 153
Beckman Coulter AU Series • BC AU BAOSR

Mean 21.97 21.97 77.91 78.11 −− −−
SD
CV
1 0.540
2.5
0.466
2.1
2 1.61
2.1
1.07
1.4
3 −−
−−
−−
−−
# Points 24 267 24 197 −− −−
# Labs 1 1 1 1

Mean 24.09 24.66 84.71 86.24 175.8 179.7
SD
CV
1 1.03
4.3
1.12
4.5
2 1.41
1.7
3.13
3.6
3 3.29
1.9
6.23
3.5
# Points 148 33184 286 35695 329 37452
# Labs 7 86 8 92 10 99

Mean −− 25.31 −− −− −− 186.0
SD
CV
1 −−
−−
0.766
3.0
2 −−
−−
−−
−−
3 −−
−−
8.64
4.6
# Points −− 217 −− −− −− 217
# Labs 1 1

Mean 22.82 24.96 80.48 85.77 167.4 176.9
SD
CV
1 0.696
3.1
1.19
4.8
2 2.46
3.1
3.92
4.6
3 4.72
2.8
7.07
4.0
# Points 62 661 62 661 62 661
# Labs 2 2 2 2 2 2
Beckman Coulter AU Series • Wako

Mean −− 27.00 −− −− −− 188.8
SD
CV
1 −−
−−
0.609
2.3
2 −−
−−
−−
−−
3 −−
−−
2.72
1.4
# Points −− 753 −− −− −− 753
# Labs 1 1

Mean −− −− 82.60 85.30 172.0 177.7
SD
CV
1 −−
−−
−−
−−
2 0.890
1.1
2.47
2.9
3 1.41
0.8
4.87
2.7
# Points −− −− 5 730 4 729
# Labs 1 2 1 2

Mean 28.14 28.96 −− 85.14 168.3 171.3
SD
CV
1 1.41
5.0
1.74
6.0
2 −−
−−
4.04
4.7
3 7.09
4.2
6.31
3.7
# Points 66 10319 −− 2315 67 9827
# Labs 2 33 8 2 30
Beckman Coulter UniCel DxC Series • Sekisui Diagnostics SEKURE

Mean −− 28.60 −− −− −− −−
SD
CV
1 −−
−−
1.46
5.1
2
−−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 52 −− −− −− −−
# Labs 2


Mean −− −− −− 87.22 −− 181.0
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.35
1.5
3 −−
−−
4.51
2.5
# Points −− −− −− 175 −− 175
# Labs 1 1
Dirui CS Series
Mean −− 24.18 −− 82.31 −− 171.2
SD
CV
1 −−
−−
1.26
5.2
2 −−
−−
2.56
3.1
3 −−
−−
5.46
3.2
# Points −− 869 −− 619 −− 630
# Labs 2 2 2

Mean −− −− 84.40 84.42 174.9 175.5
SD
CV
1 −−
−−
−−
−−
2 1.91
2.3
2.99
3.5
3 4.00
2.3
6.00
3.4
# Points −− −− 42 220 40 241
# Labs 3 3 3 3

Mean 23.65 24.37 83.53 86.33 177.6 189.5
SD
CV
1 1.81
7.7
1.87
7.7
2 4.30
5.1
6.12
7.1
3 2.79
1.6
13.10
6.9
# Points 54 667 40 553 5 44
# Labs 3 4 3 4 1 2

Mean −− 24.51 −− 85.86 −− 176.1
SD
CV
1 −−
−−
1.59
6.5
2 −−
−−
3.29
3.8
3 −−
−−
7.27
4.1
# Points −− 4748 −− 2905 −− 4809
# Labs 12 7 12

Mean −− 24.35 −− −− −− 175.7
SD
CV
1 −−
−−
0.986
4.0
2 −−
−−
−−
−−
3 −−
−−
3.81
2.2
# Points −− 89 −− −− −− 91
# Labs 1 1
Hitachi Chemistry Series • MedicalSystem Biotechnology Angiotensin Converting Enzyme Kit

Mean −− −− 83.57 84.39 −− 183.5
SD
CV
1 −−
−−
−−
−−
2
2.71
3.2
2.27
2.7
3 −−
−−
5.47
3.0
# Points −− −− 23 180 −− 168
# Labs 1 1 1

Mean −− 24.81 −− 86.92 −− 179.7
SD
CV
1 −−
−−
1.52
6.1
2 −−
−−
4.53
5.2
3 −−
−−
8.72
4.9
# Points −− 243 −− 204 −− 239
# Labs 2 1 2
Mindray BS Series
Mean 24.00 24.33 84.13 84.16 176.5 174.0
SD
CV
1 0.680
2.8
1.02
4.2
2 1.86
2.2
2.43
2.9
3 4.26
2.4
5.06
2.9
# Points 21 156 21 155 21 155
# Labs 1 1 1 1 1 1
Mindray CL Series
Mean −− −− −− 89.25 −− 187.4
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.46
1.6
3 −−
−−
2.97
1.6
# Points −− −− −− 90 −− 91
# Labs 1 1


Mean −− −− −− 85.14 −− 177.9
SD
CV
1 −−
−−
−−
−−
2 −−
−−
6.61
7.8
3 −−
−−
14.14
7.9
# Points −− −− −− 257 −− 257
# Labs 2 2

Mean 22.28 22.92 75.44 81.45 167.8 170.2
SD
CV
1 1.11
5.0
1.19
5.2
2 2.81
3.7
2.60
3.2
3 5.65
3.4
5.49
3.2
# Points 416 30752 28 19204 407 32700
# Labs 6 89 1 58 6 93

Mean 21.56 22.74 78.37 80.67 163.3 169.0
SD
CV
1 0.830
3.9
1.04
4.6
2
1.34
1.7
2.37
2.9
3 3.26
2.0
5.09
3.0
# Points 165 5291 81 2008 167 4977
# Labs 5 11 3 4 5 11

Mean −− 23.73 −− 86.65 −− 180.7
SD
CV
1 −−
−−
1.22
5.1
2 −−
−−
3.33
3.8
3 −−
−−
6.74
3.7
# Points −− 3721 −− 3741 −− 3782
# Labs 6 6 6

Mean 21.68 22.12 80.10 81.16 166.9 168.9
SD
CV
1 1.26
5.8
1.44
6.5
2 1.78
2.2
2.25
2.8
3 3.53
2.1
4.47
2.6
# Points 52 565 51 726 51 841
# Labs 1 2 1 2 1 3

Mean 22.00 21.74 79.00 78.33 168.0 164.2
SD
CV
1 1.00
4.5
1.26
5.8
2 1.00
1.3
1.94
2.5
3 1.00
0.6
3.66
2.2
# Points 32 1046 32 826 32 1019
# Labs 1 6 1 2 1 6

Mean 20.00 21.40 −− −− 158.0 161.6
SD
CV
1 1.00
5.0
1.21
5.6
2 −−
−−
−−
−−
3 3.00
1.9
4.29
2.7
# Points 19 723 −− −− 19 727
# Labs 1 2 1 2
Roche Hitachi 105−50

Mean −− 25.56 −− 93.83 −− −−
SD
CV
1 −−
−−
2.08
8.1
2 −−
−−
4.16
4.4
3 −−
−−
−−
−−
# Points −− 39 −− 41 −− −−
# Labs 1 1

Mean −− 24.74 −− 80.49 −− 166.2
SD
CV
1 −−
−−
2.08
8.4
2 −−
−−
7.73
9.6
3 −−
−−
10.59
6.4
# Points −− 679 −− 673 −− 577
# Labs 4 4 3
Mean −− 23.80 −− 86.09 −− 180.9
SD
CV
1 −−
−−
1.34
5.6
2 −−
−−
4.44
5.2
3 −−
−−
9.66
5.3
# Points −− 272 −− 540 −− 541
# Labs 1 2 2


Roche Hitachi/MODULAR • Sekisui Pureauto
Mean −− 23.24 −− −− −− 172.7
SD
CV
1 −−
−−
1.45
6.2
2 −−
−−
−−
−−
3 −−
−−
4.34
2.5
# Points −− 278 −− −− −− 278
# Labs 1 1

Mean −− −− −− 82.40 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.00
2.4
3 −−
−−
−−
−−
# Points −− −− −− 25 −− −−
# Labs 1

Mean 28.60 29.31 89.55 95.91 188.5 194.5
SD
CV
1 2.18
7.6
1.87
6.4
2 1.95
2.2
3.60
3.8
3 2.72
1.4
6.48
3.3
# Points 87 7732 22 2798 88 6318
# Labs 3 21 1 13 3 19
Siemens ADVIA Chemistry Systems • Abbott ARCH ALT REF 7D56

Mean −− 26.45 −− 89.14 −− 184.2
SD
CV
1 −−
−−
1.71
6.5
−−
−−
21.97
2.2
3 −−
−−
3.59
1.9
# Points −− 436 −− 433 −− 437
# Labs 1 1 1

Mean −− 27.76 −− 94.40 −− 196.7
SD
CV
1 −−
−−
1.22
4.4
2
−−
−−
2.40
2.5
3 −−
−−
3.95
2.0
# Points −− 1632 −− 886 −− 1633
# Labs 4 4 4
Siemens ADVIA Chemistry Systems • Fosun Diagnostics

Mean −− −− 76.29 79.99 159.5 168.0
SD
CV
1 −−
−−
−−
−−
2 3.13
4.1
3.98
5.0
3 7.06
4.4
7.79
4.6
# Points −− −− 35 559 32 553
# Labs 1 2 1 2

Mean 26.75 27.71 94.20 95.74 196.0 198.4
SD
CV
1 0.500
1.9
1.52
5.5
2 1.87
2.0
2.95
3.1
3 4.36
2.2
5.03
2.5
# Points 4 3077 36 3521 36 3420
# Labs 2 7 3 10 3 8

Mean −− 28.90 −− −− −− 197.4
SD
CV
1 −−
−−
1.05
3.6
2 −−
−−
−−
−−
3 −−
−−
2.76
1.4
# Points −− 31 −− −− −− 31
# Labs 1 1

Mean −− 27.99 −− −− −− 189.2
SD
CV
1 −−
−−
0.623
2.2
2 −−
−−
−−
−−
3 −−
−−
1.32
0.7
# Points −− 86 −− −− −− 86
# Labs 1 1
Toshiba−TBA
Mean −− −− −− −− −− 188.8
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
10.75
5.7
# Points −− −− −− −− −− 82
# Labs 1


Mean −− 25.88 −− 87.49 −− 182.6
SD
CV
1 −−
−−
1.51
5.8
2 −−
−−
2.17
2.5
3 −−
−−
4.11
2.2
# Points −− 445 −− 449 −− 455
# Labs 3 3 3

Mean −− 20.50 −− 73.53 −− −−
SD
CV
1 −−
−−
1.45
7.1
2 −−
−−
5.42
7.4
3 −−
−−
−−
−−
# Points −− 140 −− 140 −− −−
# Labs 1 1

Mean 22.31 23.75 78.46 82.38 167.0 171.0
SD
CV
1 2.06
9.2
2.58
10.9
2 5.59
7.1
6.18
7.5
3 10.88
6.5
12.38
7.2
# Points 4793 244K 3537 152K 3256 231K
# Labs 164 738 135 503 107 655

Mean −− 35.44 −− −− −− 211.9
SD
CV
1 −−
−−
2.42
6.8
−−
−−
2 −−
−−
3 −−
−−
4.20
2.0
# Points −− 142 −− −− −− 139
# Labs 1 1

Mean −− 35.44 −− −− −− 211.9
SD
CV
1 −−
−−
2.42
6.8
2 −−
−−
−−
−−
3 −−
−−
4.20
2.0
# Points −− 142 −− −− −− 139
# Labs 1 1
ALT (ALAT/GPT) UV without P5P U/L

Mean −− 24.00 −− 168.0 −− −−
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
0.000
0.0
3 −−
−−
−−
−−
# Points −− 1 −− 1 −− −−
# Labs 1 1

Mean −− 24.00 −− 168.0 −− −−
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
0.000
0.0
3 −−
−−
−−
−−
# Points −− 1 −− 1 −− −−
# Labs 1 1
Amikacin EIA µg/mL

Mean −− 6.15 −− 17.93 −− 27.22
SD
CV
1 −−
−−
0.323
5.3
2 −−
−−
1.09
6.1
3 −−
−−
1.97
7.3
# Points −− 602 −− 571 −− 588
# Labs 2 2 2

Mean −− 6.15 −− 17.93 −− 27.22
SD
CV
1 −−
−−
0.323
5.3
2 −−
−−
1.09
6.1
3 −−
−−
1.97
7.3
# Points −− 602 −− 571 −− 588
# Labs 2 2 2

Amikacin FPIA µg/mL

Mean −− 5.70 −− −− −− 30.40
SD
CV
1 −−
−−
0.424
7.4
2 −−
−−
−−
−−
3 −−
−−
1.27
4.2
# Points −− 2 −− −− −− 2
# Labs 1 1
Method Group • FPIA

Mean −− 5.70 −− −− −− 30.40
SD
CV
1 −−
−−
0.424
7.4
2 −−
−−
−−
−−
3 −−
−−
1.27
4.2
# Points −− 2 −− −− −− 2
# Labs 1 1
Amikacin Immunoturbidimetric µg/mL

Mean −− 3.60 −− 10.29 −− 15.33
SD
CV
1 −−
−−
0.453
12.6
2 −−
−−
1.81
17.6
3 −−
−−
2.60
16.9
# Points −− 445 −− 515 −− 348
# Labs 2 2 2

Mean −− 3.60 −− 10.29 −− 15.33
SD
CV
1 −−
−−
0.453
12.6
2 −−
−−
1.81
17.6
3 −−
−−
2.60
16.9
# Points −− 445 −− 515 −− 348
# Labs 2 2 2
Amikacin KIMS (Roche) µg/mL

Mean −− 5.27 −− 18.47 −− 28.82
SD
CV
1 −−
−−
0.254
4.8
2 −−
−−
0.500
2.7
3 −−
−−
0.810
2.8
# Points −− 449 −− 192 −− 452
# Labs 4 2 4

Mean −− 6.12 −− 19.23 −− 29.65
SD
CV
1 −−
−−
0.305
5.0
2 −−
−−
0.909
4.7
3 −−
−−
0.768
2.6
# Points −− 532 −− 577 −− 578
# Labs 2 2 2
Method Group • KIMS (Roche)

Mean −− 5.73 −− 19.04 −− 29.28
SD
CV
1 −−
−−
0.509
8.9
2 −−
−−
0.889
4.7
3 −−
−−
0.887
3.0
# Points −− 981 −− 769 −− 1030
# Labs 6 4 6
Amylase 2−chloro−PNP−maltoheptaose U/L @ 25° C

Mean −− 2581 −− −− −− 18362
SD
CV
1 −−
−−
88.34
3.4
2 −−
−−
−−
−−
3 −−
−−
510.3
2.8
# Points −− 42 −− −− −− 32
# Labs 1 1
Method Group • 2−chloro−PNP−maltoheptaose

Mean −− 2581 −− −− −− 18362
SD
CV
1 −−
−−
88.34
3.4
2 −−
−−
−−
−−
3 −−
−−
510.3
2.8
# Points −− 42 −− −− −− 32
# Labs 1 1

Amylase 2−chloro−PNP−maltoheptaose U/L @ 37° C

Mean −− −− −− 138.3 −− 298.9
SD
CV
1 −−
−−
−−
−−
2 −−
−−
3.29
2.4
3 −−
−−
6.79
2.3
# Points −− −− −− 602 −− 603
# Labs 3 3

Mean −− 36.02 −− −− −− 283.0
SD
CV
1 −−
−−
0.960
2.7
2 −−
−−
−−
−−
3 −−
−−
12.36
4.4
# Points −− 216 −− −− −− 216
# Labs 1 1
ERBA XL−640
Mean −− 32.33 −− 117.5 −− −−
SD
CV
1 −−
−−
0.828
2.6
2 −−
−−
3.05
2.6
3 −−
−−
−−
−−
# Points −− 55 −− 55 −− −−
# Labs 1 1

Mean −− 41.79 −− −− −− 317.0
SD
CV
1 −−
−−
0.907
2.2
2 −−
−−
−−
−−
3 −−
−−
4.42
1.4
# Points −− 458 −− −− −− 460
# Labs 3 3
Method Group • 2−chloro−PNP−maltoheptaose

Mean −− 39.36 −− 136.5 −− 302.7
SD
CV
1 −−
−−
3.40
8.6
2 −−
−−
6.63
4.9
3 −−
−−
14.18
4.7
# Points −− 729 −− 657 −− 1279
# Labs 5 4 7
Amylase Amylopectin, colorimetric U/L @ 37° C

Mean −− 39.84 −− 137.3 −− 255.2
SD
CV
1 −−
−−
0.789
2.0
2 −−
−−
2.74
2.0
3 −−
−−
3.50
1.4
# Points −− 642 −− 646 −− 640
# Labs 3 2 3

Mean −− 43.50 −− −− −− 299.3
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− 1 −− −− −− 1
# Labs 1 1
Toshiba−TBA • LEADMAN
Mean −− 46.79 −− 134.0 −− 303.4
SD
CV
1 −−
−−
1.57
3.4
2 −−
−−
3.38
2.5
3 −−
−−
29.87
9.8
# Points −− 432 −− 225 −− 409
# Labs 3 3 3

Mean −− 78.70 −− 89.02 −− 178.8
SD
CV
1 −−
−−
26.41
33.6
2 −−
−−
5.01
5.6
3 −−
−−
6.52
3.6
# Points −− 25 −− 348 −− 344
# Labs 1 1 1

Mean −− −− −− 84.66 −− 169.8
SD
CV
1 −−
−−
−−
−−
2 −−
−−
3.83
4.5
3 −−
−−
5.69
3.4
# Points −− −− −− 199 −− 200
# Labs 2 2

Amylase Amylopectin, colorimetric U/L @ 37° C

Mean −− −− −− 85.90 −− 173.3
SD
CV
1 −−
−−
−−
−−
2 −−
−−
3.74
4.4
3 −−
−−
6.11
3.5
# Points −− −− −− 448 −− 451
# Labs 2 2

Mean −− −− −− 86.47 −− 171.2
SD
CV
1 −−
−−
−−
−−
2 −−
−−
3.84
4.4
3 −−
−−
8.20
4.8
# Points −− −− −− 108 −− 108
# Labs 1 1

Mean −− −− −− 85.63 −− 168.0
SD
CV
1 −−
−−
−−
−−
2 −−
−−
3.46
4.0
3 −−
−−
5.77
3.4
# Points −− −− −− 404 −− 408
# Labs 2 2

Mean −− −− −− 79.43 −− 158.8
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.51
3.2
3 −−
−−
3.76
2.4
# Points −− −− −− 94 −− 98
# Labs 2 2

Mean −− −− −− 78.02 −− 161.7
SD
CV
1 −−
−−
−−
−−
2 −−
−−
4.34
5.6
3 −−
−−
6.25
3.9
# Points −− −− −− 185 −− 187
# Labs 2 2

Mean −− −− 84.84 85.08 165.6 167.2
SD
CV
1 −−
−−
−−
−−
2 3.83
4.5
3.66
4.3
3 5.47
3.3
5.19
3.1
# Points −− −− 64 162 64 164
# Labs 2 2 2 2
Method Group • Amylopectin, colorimetric

Mean −− 43.46 84.84 101.0 165.6 206.5
SD
CV
1 −−
−−
7.54
17.3
2 3.83
4.5
24.12
23.9
3 5.47
3.3
52.93
25.6
# Points −− 1100 64 2819 64 3010
# Labs 8 2 19 2 21
Amylase Amylopectin, colorimetric−VITROS U/L @ 37° C

Mean 37.50 32.48 80.63 85.10 159.5 164.8
SD
CV
1 0.700
1.9
2.73
8.4
2 3.49
4.3
5.10
6.0
3 4.09
2.6
7.23
4.4
# Points 15 1221 35 1566 46 1818
# Labs 1 9 2 12 2 9

Mean −− 31.10 −− 84.97 −− 176.8
SD
CV
1 −−
−−
0.866
2.8
2 −−
−−
4.73
5.6
3 −−
−−
6.70
3.8
# Points −− 3 −− 344 −− 347
# Labs 1 3 3

Mean −− −− −− 85.40 −− 178.0
SD
CV
1 −−
−−
−−
−−
2 −−
−−
5.22
6.1
3 −−
−−
10.09
5.7
# Points −− −− −− 351 −− 361
# Labs 4 4


Mean −− 81.00 −− 89.59 −− 188.2
SD
CV
1 −−
−−
4.50
5.6
2 −−
−−
6.89
7.7
3 −−
−−
6.07
3.2
# Points −− 6 −− 367 −− 469
# Labs 1 2 3

Mean −− −− −− 86.08 −− 177.6
SD
CV
1 −−
−−
−−
−−
2 −−
−−
4.46
5.2
3 −−
−−
8.52
4.8
# Points −− −− −− 485 −− 768
# Labs 6 7

Mean −− 31.65 −− 90.79 −− 174.5
SD
CV
1 −−
−−
1.59
5.0
2 −−
−−
4.60
5.1
3 −−
−−
7.44
4.3
# Points −− 40 −− 510 −− 658
# Labs 2 6 6

Mean −− 30.99 −− 82.70 −− −−
SD
CV
1 −−
−−
1.29
4.2
2 −−
−−
7.08
8.6
3 −−
−−
−−
−−
# Points −− 57 −− 89 −− −−
# Labs 1 1

Mean −− 30.49 −− 87.79 −− 173.1
SD
CV
1 −−
−−
0.890
2.9
2 −−
−−
4.84
5.5
3 −−
−−
6.99
4.0
# Points −− 40 −− 681 −− 897
# Labs 2 6 7

Mean −− 31.58 −− 90.74 −− 176.9
SD
CV
1 −−
−−
1.55
4.9
2 −−
−−
4.01
4.4
3 −−
−−
8.73
4.9
# Points −− 31 −− 602 −− 616
# Labs 3 6 7

Mean −− 32.38 −− 86.77 −− 169.1
SD
CV
1 −−
−−
1.54
4.8
2 −−
−−
3.60
4.2
3 −−
−−
5.43
3.2
# Points −− 49 −− 555 −− 917
# Labs 5 9 11

Mean −− 31.84 −− 87.59 −− 170.9
SD
CV
1 −−
−−
2.04
6.4
2 −−
−−
5.37
6.1
3 −−
−−
8.08
4.7
# Points −− 1250 −− 2658 −− 2907
# Labs 14 24 27

Mean −− 30.00 −− −− −− 182.0
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
−−
−−
3 −−
−−
3.38
1.9
# Points −− 40 −− −− −− 41
# Labs 1 1

Mean −− 33.09 −− 86.29 −− 174.6
SD
CV
1 −−
−−
2.84
8.6
2 −−
−−
4.90
5.7
3 −−
−−
8.65
5.0
# Points −− 216 −− 1930 −− 2316
# Labs 5 16 18


Mean −− 32.17 −− 86.89 −− 176.5
SD
CV
1 −−
−−
3.47
10.8
2 −−
−−
4.70
5.4
3 −−
−−
6.87
3.9
# Points −− 3345 −− 6732 −− 10718
# Labs 29 51 54

Mean −− 32.13 −− 88.09 −− 172.6
SD
CV
1 −−
−−
2.72
8.5
2 −−
−−
4.82
5.5
3 −−
−−
7.22
4.2
# Points −− 5212 −− 12256 −− 14240
# Labs 39 69 79

Mean −− 31.05 −− 88.15 −− 178.8
SD
CV
1 −−
−−
1.91
6.1
2 −−
−−
4.63
5.3
3 −−
−−
8.03
4.5
# Points −− 616 −− 5235 −− 5156
# Labs 16 41 39

Mean −− 30.00 −− −− −− 164.8
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
−−
−−
3 −−
−−
4.41
2.7
# Points −− 56 −− −− −− 75
# Labs 1 1

Mean −− 30.00 −− −− −− 166.2
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
−−
−−
3 −−
−−
3.21
1.9
# Points −− 83 −− −− −− 83
# Labs 1 1

Mean 31.60 32.96 82.76 85.28 164.8 167.8
SD
CV
1 0.000
0.0
2.70
8.2
2 3.70
4.5
4.58
5.4
3 5.08
3.1
7.78
4.6
# Points 1 1055 32 2654 32 3235
# Labs 1 18 2 30 2 32

Mean 30.00 31.84 86.33 87.67 168.1 167.5
SD
CV
1 0.000
0.0
2.01
6.3
2 3.19
3.7
4.37
5.0
3 1.99
1.2
5.87
3.5
# Points 24 1627 37 2656 12 2613
# Labs 1 14 3 26 2 28

Mean 36.46 36.65 84.95 86.19 163.4 164.6
SD
CV
1 2.36
6.5
2.44
6.7
2 3.52
4.1
4.67
5.4
3 6.00
3.7
7.63
4.6
# Points 124 1157 156 2641 207 2882
# Labs 6 12 8 23 8 22

Mean 32.81 34.65 82.05 82.88 161.0 162.1
SD
CV
1 3.23
9.9
3.26
9.4
2 4.60
5.6
4.22
5.1
3 6.37
4.0
6.07
3.7
# Points 187 1355 199 2053 303 2400
# Labs 8 18 10 25 15 27

Mean 32.26 31.96 81.84 81.44 171.0 169.0
SD
CV
1 3.28
10.2
3.28
10.3
2 4.47
5.5
4.54
5.6
3 5.91
3.5
7.10
4.2
# Points 82 254 189 792 131 666
# Labs 3 5 9 14 8 14


Mean 31.39 31.96 87.28 90.45 168.3 169.0
SD
CV
1 2.81
8.9
2.51
7.9
2 6.80
7.8
4.95
5.5
3 8.37
5.0
6.20
3.7
# Points 57 137 110 655 109 691
# Labs 4 5 6 6 6 7

Mean −− −− −− 88.45 −− 181.5
SD
CV
1 −−
−−
−−
−−
2 −−
−−
5.54
6.3
3 −−
−−
4.73
2.6
# Points −− −− −− 165 −− 167
# Labs 1 1

Mean −− −− −− 86.92 −− 172.0
SD
CV
1 −−
−−
−−
−−
2 −−
−−
4.13
4.8
3 −−
−−
5.59
3.3
# Points −− −− −− 108 −− 111
# Labs 1 1

Mean −− −− 79.07 80.91 −− 171.1
SD
CV
1 −−
−−
−−
−−
2 3.22
4.1
3.96
4.9
3 −−
−−
4.80
2.8
# Points −− −− 30 357 −− 95
# Labs 1 2 1

Mean −− −− −− 87.67 −− 180.8
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.63
3.0
3 −−
−−
3.12
1.7
# Points −− −− −− 39 −− 40
# Labs 1 1

Mean −− −− −− 91.47 −− 182.7
SD
CV
1 −−
−−
−−
−−
2 −−
−−
3.98
4.3
3 −−
−−
5.81
3.2
# Points −− −− −− 214 −− 218
# Labs 3 3

Mean −− −− −− 83.72 −− 173.0
SD
CV
1 −−
−−
−−
−−
2 −−
−−
3.31
4.0
3 −−
−−
4.06
2.3
# Points −− −− −− 57 −− 55
# Labs 1 1

Mean −− −− −− 86.59 −− 186.0
SD
CV
1 −−
−−
−−
−−
2 −−
−−
3.38
3.9
3 −−
−−
5.14
2.8
# Points −− −− −− 115 −− 118
# Labs 1 1

Mean −− −− −− −− −− 190.8
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
5.12
2.7
# Points −− −− −− −− −− 93
# Labs 1
Method Group • Amylopectin, colorimetric−VITROS

Mean 33.48 32.60 83.36 87.06 164.2 172.6
SD
CV
1 3.52
10.5
3.19
9.8
2 5.09
6.1
5.05
5.8
3 7.39
4.5
8.80
5.1
# Points 490 17877 788 46780 840 55704
# Labs 24 203 41 389 43 416

Amylase CNP−triose/CNPG3 U/L @ 25° C

Mean 42.31 43.10 138.5 139.4 −− 311.5
SD
CV
1 0.542
1.3
1.15
2.7
2 1.50
1.1
1.94
1.4
3 −−
−−
4.84
1.6
# Points 26 196 26 126 −− 351
# Labs 1 4 1 1 3

Mean −− 31.23 −− −− −− 238.9
SD
CV
1 −−
−−
1.73
5.5
2 −−
−−
−−
−−
3 −−
−−
8.05
3.4
# Points −− 328 −− −− −− 331
# Labs 1 1

Mean 42.21 41.96 146.8 145.6 323.9 321.4
SD
CV
1 0.600
1.4
0.762
1.8
2 2.30
1.6
2.05
1.4
3 5.52
1.7
4.33
1.3
# Points 32 836 31 871 32 744
# Labs 1 1 1 1 1 1
Method Group • CNP−triose/CNPG3

Mean 42.25 39.54 143.0 144.8 323.9 299.8
SD
CV
1 0.572
1.4
4.83
12.2
2 4.61
3.2
2.90
2.0
3 5.52
1.7
34.22
11.4
# Points 58 1360 57 997 32 1426
# Labs 2 6 2 2 1 5

Mean 43.24 44.05 137.8 141.6 305.0 311.1
SD
CV
1 1.44
3.3
1.51
3.4
2 3.98
2.9
4.20
3.0
3 8.80
2.9
9.51
3.1
# Points 510 33636 156 15028 507 32477
# Labs 15 113 4 55 15 108
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH AMY2 REF 04S89

Mean 40.50 41.50 132.5 134.9 −− −−
SD
CV
1 0.710
1.8
0.759
1.8
2
0.710
0.5
1.77
1.3
3 −−
−−
−−
−−
# Points 2 14 2 14 −− −−
# Labs 1 1 1 1
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH AMY2, REF 04S89 (Factored, IFCC Correlated)
Mean 41.60 41.55 135.8 135.9 −− −−
SD
CV
1 0.406
1.0
0.836
2.0
2
0.743
0.5
2.50
1.8
3 −−
−−
−−
−−
# Points 34 180 34 179 −− −−
# Labs 1 2 1 2
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c AMY2 REF 04T85

Mean −− 41.11 −− 135.0 −− −−
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
0.000
0.0
3 −−
−−
−−
−−
# Points −− 1 −− 1 −− −−
# Labs 1 1
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c AMY2, REF 04T85 (Factored, IFCC Correlated)
Mean 41.62 41.67 136.7 136.5 −− −−
SD
CV
1 0.501
1.2
0.512
1.2
2 1.19
0.9
1.60
1.2
3 −−
−−
−−
−−
# Points 64 253 67 256 −− −−
# Labs 3 5 3 5

Mean 42.19 42.23 −− −− 298.1 298.1
SD
CV
1 1.24
2.9
1.05
2.5
2 −−
−−
−−
−−
3 3.81
1.3
4.26
1.4
# Points 70 605 −− −− 68 600
# Labs 2 2 2 2


Mean 31.50 31.94 111.4 112.2 248.8 252.7
SD
CV
1 1.85
5.9
2.19
6.9
2 6.38
5.7
5.26
4.7
3 11.11
4.5
17.29
6.8
# Points 1504 50863 1192 24754 595 48908
# Labs 48 171 38 93 19 144
Beckman Coulter AU Series • Alternate Formulation/Standardization

Mean −− 31.16 −− −− −− 240.4
SD
CV
1 −−
−−
1.02
3.3
−−
−−
2 −−
−−
3 −−
−−
5.32
2.2
# Points −− 163 −− −− −− 164
# Labs 1 1

Mean 37.47 37.50 133.9 134.0 288.8 290.2
SD
CV
1 0.605
1.6
0.744
2.0
2 3.60
2.7
3.76
2.8
3 5.32
1.8
6.09
2.1
# Points 85 2053 265 5002 265 4706
# Labs 2 4 6 11 6 9

Mean −− 44.08 −− −− −− 286.6
SD
CV
1 −−
−−
0.748
1.7
2 −−
−−
−−
−−
3 −−
−−
5.87
2.0
# Points −− 86 −− −− −− 89
# Labs 1 1
Mindray BS Series
Mean −− 47.57 −− 138.6 −− 293.8
SD
CV
1 −−
−−
0.671
1.4
2 −−
−−
2.22
1.6
3 −−
−−
4.48
1.5
# Points −− 89 −− 321 −− 322
# Labs 1 1 1

Mean −− 43.63 −− 130.2 −− 275.7
SD
CV
1 −−
−−
0.700
1.6
2 −−
−−
1.81
1.4
3 −−
−−
3.75
1.4
# Points −− 589 −− 920 −− 499
# Labs 1 1 1

Mean −− 26.81 −− 95.36 −− −−
SD
CV
1 −−
−−
1.14
4.2
2 −−
−−
4.00
4.2
3 −−
−−
−−
−−
# Points −− 43 −− 33 −− −−
# Labs 1 1
Siemens ADVIA Chemistry Systems • Abbott

Mean −− 40.97 −− 128.4 −− 271.0
SD
CV
1 −−
−−
1.28
3.1
2 −−
−−
3.72
2.9
3 −−
−−
8.33
3.1
# Points −− 116 −− 115 −− 117
# Labs 2 2 2

Mean −− 42.47 −− 132.2 −− 279.8
SD
CV
1 −−
−−
0.872
2.1
2 −−
−−
17.39
13.2
3 −−
−−
3.95
1.4
# Points −− 1121 −− 379 −− 917
# Labs 4 5 3

Mean 41.78 42.19 144.9 146.7 323.1 323.9
SD
CV
1 1.10
2.6
1.05
2.5
2 3.51
2.4
2.80
1.9
3 5.54
1.7
6.27
1.9
# Points 789 59694 93 7175 719 55953
# Labs 30 167 3 30 28 153


Mean 41.78 42.10 148.1 149.3 328.0 329.9
SD
CV
1 0.922
2.2
0.943
2.2
2 2.91
2.0
2.58
1.7
3 5.63
1.7
5.84
1.8
# Points 1874 190K 619 47886 2066 187K
# Labs 60 427 17 107 65 415
Thermo Konelab 20/30/60i • Sekisui Diagnostics SEKURE

Mean −− −− 121.7 121.4 −− −−
SD
CV
1 −−
−−
−−
−−
4.37
3.6
2 3.89
3.2
3 −−
−−
−−
−−
# Points −− −− 10 16 −− −−
# Labs 1 1
Method Group • CNP−triose/CNPG3

Mean 39.08 40.85 127.2 137.8 312.7 315.3
SD
CV
1 5.54
14.2
4.14
10.1
2 16.91
13.3
15.65
11.4
3 31.94
10.2
29.40
9.3
# Points 5039 342K 2438 102K 4326 333K
# Labs 164 905 74 316 137 841
Amylase EIA U/L @ 37° C

Mean −− 37.81 −− −− −− 293.1
SD
CV
1 −−
−−
0.847
2.2
2 −−
−−
−−
−−
3 −−
−−
4.03
1.4
# Points −− 438 −− −− −− 465
# Labs 1 1

Mean −− 37.81 −− −− −− 293.1
SD
CV
1 −−
−−
0.847
2.2
2 −−
−−
−−
−−
3 −−
−−
4.03
1.4
# Points −− 438 −− −− −− 465
# Labs 1 1
Amylase G7 PNP U/L @ 37° C

Mean 42.63 42.58 136.5 136.7 295.3 296.5
SD
CV
1 0.630
1.5
0.863
2.0
2 1.54
1.1
1.86
1.4
3 4.18
1.4
4.37
1.5
# Points 38 625 38 625 38 625
# Labs 1 1 1 1 1 1
Mean 41.49 41.67 136.2 136.6 −− 299.0
SD
CV
1 0.698
1.7
0.681
1.6
2
2.04
1.5
1.60
1.2
3 −−
−−
0.000
0.0
# Points 82 498 82 495 −− 1
# Labs 4 4 4 4 1
Mean 41.19 41.33 135.0 135.5 −− −−
SD
CV
1 0.541
1.3
0.451
1.1
2 1.86
1.4
1.30
1.0
3 −−
−−
−−
−−
# Points 31 213 31 213 −− −−
# Labs 1 1 1 1

Mean −− −− −− 138.2 −− 296.5
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.36
1.0
3 −−
−−
2.67
0.9
# Points −− −− −− 171 −− 171
# Labs 1 1

Amylase G7 PNP U/L @ 37° C

Mean 36.30 34.08 121.9 114.9 249.6 236.4
SD
CV
1 2.72
7.5
2.57
7.6
2 9.59
7.9
7.41
6.5
3 8.56
3.4
9.03
3.8
# Points 20 234 18 196 5 41
# Labs 1 2 1 2 1 1
Fuji Dri−Chem Series • Fuji Dri−Chem AMYL−PIII, REF 9903030

Mean −− 52.75 −− 137.4 −− −−
SD
CV
1 −−
−−
1.81
3.4
−−
−−
2 3.22
2.3
3 −−
−−
−−
−−
# Points −− 16 −− 16 −− −−
# Labs 2 2

Mean −− −− −− 126.4 −− 270.2
SD
CV
1 −−
−−
−−
−−
2
−−
−−
3.28
2.6
3 −−
−−
6.26
2.3
# Points −− −− −− 108 −− 107
# Labs 1 1

Mean −− 43.64 −− 131.4 −− 280.0
SD
CV
1 −−
−−
0.683
1.6
2 −−
−−
1.92
1.5
3 −−
−−
3.97
1.4
# Points −− 546 −− 537 −− 549
# Labs 1 1 1

Mean 43.07 43.59 129.0 130.5 275.1 279.2
SD
CV
1 0.620
1.4
0.748
1.7
2 1.62
1.3
1.93
1.5
3 3.08
1.1
3.68
1.3
# Points 14 267 14 267 14 267
# Labs 1 1 1 1 1 1

Mean −− −− −− 131.0 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.60
2.0
3 −−
−−
−−
−−
# Points −− −− −− 178 −− −−
# Labs 1

Mean −− 45.10 −− −− −− 292.3
SD
CV
1 −−
−−
0.734
1.6
2 −−
−−
−−
−−
3 −−
−−
4.82
1.7
# Points −− 1536 −− −− −− 1553
# Labs 2 2
Method Group • G7 PNP

Mean 41.23 43.14 134.1 133.0 286.3 289.4
SD
CV
1 2.11
5.1
2.87
6.7
2 5.64
4.2
6.34
4.8
3 15.01
5.2
9.84
3.4
# Points 185 3938 183 2701 57 3207
# Labs 8 14 8 14 3 8
Amylase G7 PNP with B−glucosidase U/L @ 37° C

Mean 41.78 41.93 137.9 137.7 −− −−
SD
CV
1 0.760
1.8
0.725
1.7
2
1.40
1.0
1.79
1.3
3 −−
−−
−−
−−
# Points 31 144 31 143 −− −−
# Labs 1 2 1 2
Abbott ARCHITECT/Alinity (c, i, ci models) • MAKER

Mean 45.56 45.64 140.6 139.7 294.9 296.3
SD
CV
1 0.580
1.3
0.650
1.4
2 2.36
1.7
1.77
1.3
3 1.77
0.6
3.08
1.0
# Points 25 369 25 412 25 416
# Labs 1 1 1 1 1 1

Amylase G7 PNP with B−glucosidase U/L @ 37° C

Mean −− 44.68 −− 135.1 −− 288.7
SD
CV
1 −−
−−
0.656
1.5
2 −−
−−
1.55
1.1
3 −−
−−
3.89
1.3
# Points −− 671 −− 942 −− 670
# Labs 4 4 4
Method Group • G7 PNP with B−glucosidase

Mean 43.47 44.64 139.1 136.6 294.9 291.6
SD
CV
1 2.01
4.6
1.28
2.9
2 2.33
1.7
2.59
1.9
3 1.77
0.6
5.16
1.8
# Points 56 1184 56 1497 25 1086
# Labs 2 7 2 7 1 5
Amylase G7 PNP, Blocked U/L @ 37° C

Mean −− 44.91 −− 143.4 −− 310.0
SD
CV
1 −−
−−
1.01
2.3
2 −−
−−
2.32
1.6
3 −−
−−
5.16
1.7
# Points −− 240 −− 240 −− 238
# Labs 1 1 1
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH AMY2 REF 04S89

Mean 41.65 41.65 135.7 135.7 −− −−
SD
CV
1 0.562
1.3
0.562
1.3
2
1.54
1.1
1.54
1.1
3 −−
−−
−−
−−
# Points 26 26 26 26 −− −−
# Labs 1 1 1 1

Mean −− −− −− 130.7 −− 279.5
SD
CV
1 −−
−−
−−
−−
2 −−
−−
4.72
3.6
3 −−
−−
10.30
3.7
# Points −− −− −− 586 −− 580
# Labs 2 2

Mean −− 36.73 139.3 128.8 295.5 277.4
SD
CV
1 −−
−−
6.91
18.8
2 1.54
1.1
12.18
9.5
3 2.59
0.9
22.23
8.0
# Points −− 2254 31 4505 31 4747
# Labs 5 1 13 1 14

Mean −− 41.93 −− 130.5 −− 282.5
SD
CV
1 −−
−−
3.12
7.4
2 −−
−−
10.44
8.0
3 −−
−−
21.38
7.6
# Points −− 151 −− 151 −− 150
# Labs 1 1 1

Mean −− −− 130.8 129.7 282.5 278.7
SD
CV
1 −−
−−
−−
−−
2 0.450
0.3
2.06
1.6
3 4.36
1.5
3.99
1.4
# Points −− −− 5 731 4 730
# Labs 1 2 1 2
Beckman Coulter UniCel DxC Series • Fosun Diagnostics

Mean −− 38.82 −− 118.7 −− 258.9
SD
CV
1 −−
−−
2.56
6.6
2 −−
−−
3.80
3.2
3 −−
−−
5.90
2.3
# Points −− 38 −− 37 −− 38
# Labs 1 1 1

Mean −− −− 138.1 132.9 288.9 282.5
SD
CV
1 −−
−−
−−
−−
2 2.25
1.6
4.91
3.7
3 5.48
1.9
9.53
3.4
# Points −− −− 42 220 41 221
# Labs 3 3 3 3


Mean −− −− −− 132.4 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
4.34
3.3
3 −−
−−
−−
−−
# Points −− −− −− 41 −− −−
# Labs 1

Mean −− 42.02 −− 131.0 −− 282.2
SD
CV
1 −−
−−
1.17
2.8
2 −−
−−
4.03
3.1
3 −−
−−
8.41
3.0
# Points −− 2706 −− 2839 −− 2831
# Labs 6 8 7

Mean −− 46.84 −− −− −− −−
SD
CV
1 −−
−−
0.454
1.0
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 61 −− −− −− −−
# Labs 1

Mean −− 46.00 −− −− −− 303.3
SD
CV
1 −−
−−
2.87
6.2
2 −−
−−
−−
−−
3 −−
−−
11.39
3.8
# Points −− 9 −− −− −− 9
# Labs 1 1

Mean −− −− −− 130.1 −− 277.0
SD
CV
1 −−
−−
−−
−−
2 −−
−−
3.50
2.7
3 −−
−−
11.12
4.0
# Points −− −− −− 236 −− 263
# Labs 2 2
RANDOX RX daytona
Mean 36.55 35.66 124.2 118.9 122.3 201.2
SD
CV
1 5.17
14.2
4.35
12.2
2 18.25
14.7
14.29
12.0
3 0.000
0.0
111.5
55.4
# Points 44 394 28 282 1 2
# Labs 2 2 2 2 1 2
RANDOX RX imola
Mean 42.81 43.12 133.5 135.0 −− −−
SD
CV
1 1.41
3.3
2.78
6.5
2 1.41
1.1
4.13
3.1
3 −−
−−
−−
−−
# Points 26 226 24 195 −− −−
# Labs 1 1 1 1

Mean 43.29 43.28 129.3 129.4 275.1 275.1
SD
CV
1 0.850
2.0
0.980
2.3
2 1.70
1.3
2.73
2.1
3 4.65
1.7
5.21
1.9
# Points 1651 54634 255 28142 1564 57124
# Labs 36 150 8 85 34 158
Roche cobas 6000/8000/c 311 • 2nd Generation

Mean −− 44.61 −− −− −− 283.6
SD
CV
1 −−
−−
0.853
1.9
2 −−
−−
−−
−−
3 −−
−−
4.94
1.7
# Points −− 503 −− −− −− 516
# Labs 4 4

Mean 43.11 43.11 129.1 129.0 272.3 273.6
SD
CV
1 0.537
1.2
0.789
1.8
2 1.59
1.2
2.07
1.6
3 2.75
1.0
4.60
1.7
# Points 125 3746 128 3353 76 3367
# Labs 4 12 4 8 3 11


Roche cobas c 303/503 • Roche AMYL2, REF 08056811
Mean 43.29 43.12 128.1 129.6 272.6 273.2
SD
CV
1 0.547
1.3
0.829
1.9
2 1.06
0.8
1.47
1.1
3 3.65
1.3
4.80
1.8
# Points 111 6960 27 2412 93 7061
# Labs 4 21 1 5 3 20

Mean 43.04 42.87 129.4 129.5 278.1 278.4
SD
CV
1 0.849
2.0
0.950
2.2
2 2.07
1.6
2.18
1.7
3 6.54
2.4
5.81
2.1
# Points 189 1620 196 1892 113 930
# Labs 4 5 4 5 3 5

Mean 44.64 44.13 133.0 131.9 279.4 279.0
SD
CV
1 0.858
1.9
1.11
2.5
2 1.00
0.8
2.51
1.9
3 3.03
1.1
4.77
1.7
# Points 65 2634 31 687 65 2618
# Labs 2 7 1 1 2 7

Mean 41.74 39.07 129.6 121.8 277.7 261.4
SD
CV
1 0.630
1.5
3.77
9.6
2 1.29
1.0
10.87
8.9
3 1.71
0.6
23.04
8.8
# Points 31 855 31 855 31 854
# Labs 1 3 1 3 1 3
Mean −− 42.15 −− 131.5 −− 282.1
SD
CV
1 −−
−−
1.30
3.1
2 −−
−−
2.94
2.2
3 −−
−−
8.21
2.9
# Points −− 271 −− 270 −− 266
# Labs 1 2 1

Mean −− −− −− 138.4 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
7.05
5.1
3 −−
−−
−−
−−
# Points −− −− −− 7 −− −−
# Labs 1

Mean 42.65 42.85 129.2 129.2 281.5 282.5
SD
CV
1 1.40
3.3
1.82
4.2
2 2.85
2.2
3.72
2.9
3 8.79
3.1
10.11
3.6
# Points 123 11597 92 9548 88 12258
# Labs 4 26 4 21 4 26

Mean 47.85 47.67 145.1 145.9 307.3 307.6
SD
CV
1 1.69
3.5
2.21
4.6
2 5.07
3.5
5.92
4.1
3 20.08
6.5
15.35
5.0
# Points 442 19618 371 10786 100 13857
# Labs 12 62 10 39 5 49
Siemens Atellica CH Analyzer • Siemens Atellica CH AMY_2 REF 11097649

Mean −− 48.42 −− −− −− 315.8
SD
CV
1 −−
−−
0.707
1.5
2
−−
−−
−−
−−
3 −−
−−
4.22
1.3
# Points −− 182 −− −− −− 179
# Labs 2 2
Method Group • G7 PNP, Blocked

Mean 43.84 43.81 134.6 132.0 277.4 280.5
SD
CV
1 2.29
5.2
2.77
6.3
2 8.27
6.1
7.95
6.0
3 10.26
3.7
14.52
5.2
# Points 2833 109K 1287 68041 2207 109K
# Labs 71 313 42 208 61 322

Amylase G7 PNP, Blocked − IFCC Ref. Proc., Calibrated U/L @ 25° C

Beckman Coulter UniCel DxC Series • Factored, IFCC Correlated
Mean −− 45.56 −− −− −− 294.5
SD
CV
1 −−
−−
1.12
2.5
2
−−
−−
−−
−−
3 −−
−−
3.81
1.3
# Points −− 298 −− −− −− 298
# Labs 1 1

Mean −− 43.89 −− −− −− 273.5
SD
CV
1 −−
−−
0.685
1.6
2 −−
−−
−−
−−
3 −−
−−
8.12
3.0
# Points −− 498 −− −− −− 493
# Labs 1 1

Mean 44.23 44.06 −− −− 280.0 277.9
SD
CV
1 0.496
1.1
0.692
1.6
2 −−
−−
−−
−−
3 1.91
0.7
3.93
1.4
# Points 34 814 −− −− 34 769
# Labs 1 1 1 1

Mean −− 48.65 −− 148.0 −− 316.5
SD
CV
1 −−
−−
0.751
1.5
2 −−
−−
1.73
1.2
3 −−
−−
3.84
1.2
# Points −− 936 −− 999 −− 987
# Labs 1 1 1
Method Group • G7 PNP, Blocked − IFCC Ref. Proc., Calibrated

Mean 44.23 46.38 −− 148.0 280.0 298.9
SD
CV
1 0.496
1.1
2.28
4.9
2
−−
−−
1.73
1.2
3 1.91
0.7
18.22
6.1
# Points 34 2048 −− 999 34 2054
# Labs 1 3 1 1 3

Mean −− 48.01 −− 153.7 −− 340.2
SD
CV
1 −−
−−
1.28
2.7
2 −−
−−
5.40
3.5
3 −−
−−
9.91
2.9
# Points −− 2081 −− 1958 −− 2339
# Labs 4 4 5
Mean 41.49 41.92 135.8 136.9 −− 298.8
SD
CV
1 1.17
2.8
0.913
2.2
2
3.53
2.6
3.79
2.8
3 −−
−−
2.99
1.0
# Points 220 2291 222 1272 −− 1961
# Labs 10 19 11 14 5
Mean 42.14 42.50 137.9 139.0 301.0 303.5
SD
CV
1 1.36
3.2
1.47
3.5
2 4.11
3.0
4.50
3.2
3 5.13
1.7
7.20
2.4
# Points 234 1798 257 1649 99 731
# Labs 12 20 13 19 6 9
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c, Amylase, REF 07P58 (Factored, IFCC Correlated)
Mean −− 47.94 −− 155.6 −− 342.4
SD
CV
1 −−
−−
1.20
2.5
2 −−
−−
3.24
2.1
3 −−
−−
6.70
2.0
# Points −− 1640 −− 1396 −− 1644
# Labs 3 2 3

Mean 46.25 44.75 149.7 144.6 334.7 318.9
SD
CV
1 2.98
6.5
3.05
6.8
29.89
6.6
9.81
6.8
3 23.91
7.1
24.53
7.7
# Points 35 814 32 803 35 818
# Labs 2 2 2 2 2 2


Mean 43.84 44.33 131.6 134.1 278.9 285.3
SD
CV
1 0.576
1.3
1.53
3.4
2 1.58
1.2
3.92
2.9
3 3.01
1.1
7.57
2.7
# Points 102 6212 103 8488 100 8441
# Labs 2 18 2 22 2 22

Mean −− −− −− 128.0 −− 273.8
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.72
1.3
3 −−
−−
4.18
1.5
# Points −− −− −− 161 −− 161
# Labs 1 1

Mean 44.47 44.75 136.7 135.5 284.3 287.0
SD
CV
1 1.15
2.6
1.84
4.1
2 2.13
1.6
5.47
4.0
3 5.96
2.1
11.30
3.9
# Points 61 23095 18 22232 61 22869
# Labs 4 61 1 55 3 61
Beckman Coulter UniCel DxC Series • Factored, IFCC Correlated

Mean 45.20 45.89 −− 139.4 291.2 296.4
SD
CV
1 1.08
2.4
1.25
2.7
2 −−
−−
3.78
2.7
3 5.81
2.0
5.42
1.8
# Points 61 11615 −− 1737 70 7894
# Labs 2 30 6 2 28

Mean −− 42.56 −− −− −− 272.8
SD
CV
1 −−
−−
0.765
1.8
2 −−
−−
−−
−−
3 −−
−−
4.47
1.6
# Points −− 502 −− −− −− 648
# Labs 3 3

Mean −− 43.44 −− 129.2 −− 274.6
SD
CV
1 −−
−−
0.791
1.8
2 −−
−−
1.18
0.9
3 −−
−−
3.46
1.3
# Points −− 697 −− 454 −− 704
# Labs 3 2 3

Mean 43.34 43.43 −− −− −− −−
SD
CV
1 0.630
1.5
0.666
1.5
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points 105 164 −− −− −− −−
# Labs 2 2

Mean 47.10 48.82 146.3 137.0 314.6 317.1
SD
CV
1 0.226
0.5
0.820
1.7
2 8.17
5.6
6.21
4.5
3 8.05
2.6
4.55
1.4
# Points 2 3430 13 399 9 2890
# Labs 1 15 3 8 1 10
Siemens Atellica CH Analyzer • Siemens Atellica CH AMY_2 REF 11097649

Mean 49.13 48.74 −− −− 318.2 316.9
SD
CV
1 0.745
1.5
0.984
2.0
2−−
−−
−−
−−
3 6.46
2.0
6.19
2.0
# Points 64 1092 −− −− 63 1065
# Labs 2 2 2 2
Toshiba−TBA
Mean −− −− −− −− −− 284.3
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
8.87
3.1
# Points −− −− −− −− −− 83
# Labs 1


Method Group • G7 PNP, Blocked − IFCC Ref. Proc., Calibrated
Mean 43.37 45.26 136.9 137.3 297.5 295.4
SD
CV
1 2.42
5.6
2.25
5.0
2
5.73
4.2
7.54
5.5
3 19.01
6.4
18.83
6.4
# Points 884 55431 645 40502 437 52087
# Labs 37 182 32 136 18 154
Amylase G7 PNP, Blocked, Factored U/L @ 37° C

Mean −− 41.42 −− 143.0 −− 296.4
SD
CV
1 −−
−−
0.584
1.4
2−−
−−
1.22
0.9
3 −−
−−
3.44
1.2
# Points −− 24 −− 23 −− 37
# Labs 1 1 1
Beckman Coulter UniCel DxC Series • Factored (excluding IFCC)

Mean −− 46.07 −− −− −− −−
SD
CV
1 −−
−−
1.06
2.3
−−
−−
2 −−
−−
3 −−
−−
−−
−−
# Points −− 409 −− −− −− −−
# Labs 1
Method Group • G7 PNP, Blocked, Factored

Mean −− 45.82 −− 143.0 −− 296.4
SD
CV
1 −−
−−
1.49
3.2
2 −−
−−
1.22
0.9
3 −−
−−
3.44
1.2
# Points −− 433 −− 23 −− 37
# Labs 2 1 1
Amylase Gal−G2 CNP U/L @ 37° C

Mean 43.60 43.01 142.6 143.5 −− −−
SD
CV
1 1.26
2.9
1.40
3.2
2 3.50
2.5
3.41
2.4
3 −−
−−
−−
−−
# Points 10 267 10 200 −− −−
# Labs 1 1 1 1

Mean −− 50.50 −− −− −− 396.7
SD
CV
1 −−
−−
1.04
2.1
2 −−
−−
−−
−−
3 −−
−−
6.24
1.6
# Points −− 1623 −− −− −− 1624
# Labs 5 5

Mean −− 51.55 −− −− −− 402.9
SD
CV
1 −−
−−
1.13
2.2
2 −−
−−
−−
−−
3 −−
−−
6.17
1.5
# Points −− 278 −− −− −− 278
# Labs 1 1
Method Group • Gal−G2 CNP

Mean 43.60 49.71 142.6 143.5 −− 397.6
SD
CV
1 1.26
2.9
2.76
5.6
2 3.50
2.5
3.41
2.4
3 −−
−−
6.60
1.7
# Points 10 2168 10 200 −− 1902
# Labs 1 7 1 1 6
Amylase, Pancreatic CNP−maltoheptaoside U/L @ 37° C

Mean 21.16 20.27 97.92 99.14 230.3 237.5
SD
CV
1 0.950
4.5
0.835
4.1
2 0.910
0.9
1.43
1.4
3 2.62
1.1
3.60
1.5
# Points 38 626 38 626 38 626
# Labs 1 1 1 1 1 1

Amylase, Pancreatic CNP−maltoheptaoside U/L @ 37° C

Method Group • CNP−maltoheptaoside
Mean 21.74 20.31 97.92 99.14 230.3 237.5
SD
CV
1 3.02
13.9
1.15
5.7
2 0.910
0.9
1.43
1.4
3 2.62
1.1
3.60
1.5
# Points 42 630 38 626 38 626
# Labs 2 2 1 1 1 1
Amylase, Pancreatic G7 PNP immunoinhibition U/L @ 37° C

Mean −− 21.09 −− 99.39 −− 236.8
SD
CV
1 −−
−−
0.310
1.5
2 −−
−−
0.968
1.0
3 −−
−−
2.32
1.0
# Points −− 311 −− 311 −− 311
# Labs 2 2 2

Mean 20.00 20.53 −− 93.43 226.8 222.4
SD
CV
1 0.000
0.0
0.883
4.3
2 −−
−−
3.98
4.3
3 1.41
0.6
7.45
3.3
# Points 21 1146 −− 1395 21 2094
# Labs 1 2 3 1 4

Mean 21.85 21.97 −− 126.0 234.6 242.1
SD
CV
1 0.362
1.7
0.432
2.0
2 −−
−−
3.38
2.7
3 1.74
0.7
13.07
5.4
# Points 150 3057 −− 769 151 3822
# Labs 2 3 2 2 6

Mean 1.37 1.34 6.00 5.99 14.19 14.22
SD
CV
1 0.022
1.6
0.034
2.5
2 0.037
0.6
0.057
1.0
3 0.119
0.8
0.113
0.8
# Points 14 268 14 268 14 268
# Labs 1 1 1 1 1 1
Mean −− −− −− 140.2 −− 302.4
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.73
1.9
3 −−
−−
6.64
2.2
# Points −− −− −− 342 −− 341
# Labs 1 1

Mean −− 22.80 −− −− −− 242.3
SD
CV
1 −−
−−
0.575
2.5
2 −−
−−
−−
−−
3 −−
−−
2.96
1.2
# Points −− 331 −− −− −− 331
# Labs 1 1
Method Group • G7 PNP immunoinhibition

Mean 21.64 22.00 78.79 102.5 217.1 230.5
SD
CV
1 6.57
30.4
6.07
27.6
2 55.27
70.1
31.18
30.4
3 58.12
26.8
46.96
20.4
# Points 211 5717 39 3913 186 7167
# Labs 5 10 2 10 4 15
Amylase, Pancreatic G7 PNP, Blocked U/L @ 37° C

Mean 20.74 21.26 97.46 100.3 232.5 241.2
SD
CV
1 0.865
4.2
1.48
7.0
2 3.62
3.7
6.43
6.4
3 8.92
3.8
19.40
8.0
# Points 96 1485 83 1042 84 1305
# Labs 5 6 5 6 5 7


Abbott ARCHITECT/Alinity (c, i, ci models) • Roche
Mean −− −− −− 95.75 −− 228.1
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.52
2.6
3 −−
−−
5.87
2.6
# Points −− −− −− 579 −− 577
# Labs 2 2

Mean −− 20.88 −− 95.30 −− 224.6
SD
CV
1 −−
−−
0.526
2.5
2 −−
−−
3.57
3.7
3 −−
−−
8.25
3.7
# Points −− 10 −− 10 −− 10
# Labs 1 1 1
Beckman Coulter AU Series • Roche

Mean −− −− 102.0 96.80 242.5 231.3
SD
CV
1 −−
−−
−−
−−
2 0.000
0.0
2.83
2.9
3 1.29
0.5
6.84
3.0
# Points −− −− 5 648 4 648
# Labs 1 2 1 2
Dirui CS Series • Roche

Mean −− −− 105.4 103.1 250.3 245.9
SD
CV
1 −−
−−
−−
−−
2 3.06
2.9
5.02
4.9
3 9.47
3.8
16.16
6.6
# Points −− −− 43 247 41 247
# Labs 3 3 3 3
Mindray CL Series • Roche

Mean −− −− −− 95.59 −− 226.4
SD
CV
1 −−
−−
−−
−−
2 −−
−−
4.28
4.5
3 −−
−−
10.29
4.5
# Points −− −− −− 280 −− 277
# Labs 2 2

Mean 22.10 22.30 96.52 97.82 228.2 232.2
SD
CV
1 0.505
2.3
0.540
2.4
2 0.827
0.9
1.69
1.7
3 2.42
1.1
4.37
1.9
# Points 27 366 28 352 29 374
# Labs 1 1 1 1 1 1
Roche cobas c 303/503 • Roche AMY−P, REF 08056820

Mean −− 43.28 −− 129.2 −− 274.5
SD
CV
1 −−
−−
0.501
1.2
2 −−
−−
1.16
0.9
3 −−
−−
2.40
0.9
# Points −− 108 −− 108 −− 107
# Labs 2 2 2

Mean 22.60 22.68 100.4 100.6 238.9 239.4
SD
CV
1 0.470
2.1
0.546
2.4
2 1.63
1.6
1.56
1.6
3 3.38
1.4
3.66
1.5
# Points 51 444 51 447 51 447
# Labs 1 1 1 1 1 1

Mean −− 23.67 145.3 92.12 −− 268.5
SD
CV
1 −−
−−
2.88
12.2
2 1.07
0.7
9.21
10.0
3 −−
−−
19.23
7.2
# Points −− 395 2 222 −− 208
# Labs 6 1 3 5
Siemens Dimension Series • Sentinel

Mean 21.32 21.77 −− −− 231.0 230.9
SD
CV
1 1.70
8.0
1.54
7.1
2 −−
−−
−−
−−
3 6.23
2.7
6.21
2.7
# Points 143 3199 −− −− 117 2910
# Labs 3 4 3 4


Method Group • G7 PNP, Blocked
Mean 21.84 21.45 98.41 97.10 233.7 233.0
SD
CV
1 1.61
7.4
2.30
10.7
2 5.06
5.1
4.76
4.9
3 8.13
3.5
11.41
4.9
# Points 829 23912 423 15362 636 13466
# Labs 22 37 20 36 18 34
Amylase, Pancreatic G7 PNP, Blocked, Factored U/L @ 37° C

Mean −− 46.20 −− 134.2 −− 278.1
SD
CV
1 −−
−−
3.93
8.5
2 −−
−−
6.69
5.0
3 −−
−−
10.47
3.8
# Points −− 276 −− 270 −− 265
# Labs 2 2 2

Mean −− −− −− 101.6 −− 243.7
SD
CV
1 −−
−−
−−
−−
2−−
−−
1.68
1.6
3 −−
−−
3.85
1.6
# Points −− −− −− 161 −− 161
# Labs 1 1

Mean −− 23.90 −− 105.4 −− 250.9
SD
CV
1 −−
−−
0.683
2.9
2 −−
−−
2.40
2.3
3 −−
−−
5.76
2.3
# Points −− 491 −− 488 −− 490
# Labs 2 2 2
Method Group • G7 PNP, Blocked, Factored

Mean −− 31.92 −− 115.7 −− 260.5
SD
CV
1 −−
−−
10.98
34.4
2 −−
−−
14.46
12.5
3 −−
−−
15.13
5.8
# Points −− 767 −− 758 −− 755
# Labs 4 4 4
Apolipoprotein A Immunoturbidimetric mg/dL

Mean −− 82.34 −− 102.0 −− 136.1
SD
CV
1 −−
−−
3.37
4.1
2 −−
−−
5.12
5.0
3 −−
−−
5.58
4.1
# Points −− 479 −− 2257 −− 2245
# Labs 1 7 7

Mean −− −− −− 104.3 −− 139.6
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.61
2.5
3 −−
−−
3.77
2.7
# Points −− −− −− 58 −− 57
# Labs 1 1

Mean −− −− −− 100.5 −− 136.6
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.25
2.2
3 −−
−−
3.12
2.3
# Points −− −− −− 792 −− 842
# Labs 1 1

Mean −− 82.34 −− 101.6 −− 136.2
SD
CV
1 −−
−−
3.37
4.1
2 −−
−−
4.60
4.5
3 −−
−−
5.03
3.7
# Points −− 479 −− 3049 −− 3087
# Labs 1 8 8

Apolipoprotein A−I Immunonephelometric, end point mg/dL

Mean −− 81.57 −− −− −− 137.9
SD
CV
1 −−
−−
6.33
7.8
2 −−
−−
−−
−−
3 −−
−−
10.72
7.8
# Points −− 1018 −− −− −− 1019
# Labs 4 4
Beckman Coulter AU Series • DiaSys Diagnostic Systems

Mean −− 75.20 −− 100.00 −− 136.0
SD
CV
1 −−
−−
3.06
4.1
2 −−
−−
5.22
5.2
3 −−
−−
7.80
5.7
# Points −− 1069 −− 1011 −− 1002
# Labs 2 2 2

Mean −− −− −− 106.3 −− 145.7
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.13
2.0
3 −−
−−
2.86
2.0
# Points −− −− −− 169 −− 169
# Labs 1 1
Mindray BS Series
Mean −− 79.37 −− 143.7 −− −−
SD
CV
1 −−
−−
3.90
4.9
2 −−
−−
2.87
2.0
3 −−
−−
−−
−−
# Points −− 227 −− 224 −− −−
# Labs 1 1
Method Group • Immunonephelometric, end point

Mean −− 78.41 −− 107.7 −− 137.6
SD
CV
1 −−
−−
5.71
7.3
2 −−
−−
16.46
15.3
3 −−
−−
9.39
6.8
# Points −− 2314 −− 1405 −− 2190
# Labs 7 4 7
Apolipoprotein A−I Immunonephelometric, kinetic mg/dL

Mean −− −− −− 92.01 −− 115.1
SD
CV
1 −−
−−
−−
−−
2 −−
−−
6.20
6.7
3 −−
−−
10.82
9.4
# Points −− −− −− 652 −− 654
# Labs 2 2
Method Group • Immunonephelometric, kinetic

Mean −− −− −− 92.01 −− 115.1
SD
CV
1 −−
−−
−−
−−
2 −−
−−
6.20
6.7
3 −−
−−
10.82
9.4
# Points −− −− −− 652 −− 654
# Labs 2 2
Apolipoprotein A−I Immunoturbidimetric mg/dL

Mean 77.00 80.85 −− 105.6 150.0 138.9
SD
CV
1 1.000
1.3
3.68
4.6
2 −−
−−
4.95
4.7
3 1.00
0.7
7.29
5.3
# Points 19 1096 −− 1167 19 1191
# Labs 1 4 5 1 6

Mean 85.00 83.76 111.0 110.6 −− 145.6
SD
CV
1 1.000
1.2
1.91
2.3
2
1.00
0.9
2.28
2.1
3 −−
−−
2.59
1.8
# Points 24 1434 2 1239 −− 1329
# Labs 1 1 1 1 1


Mean −− 79.25 106.3 102.5 141.7 138.7
SD
CV
1 −−
−−
6.08
7.7
2 2.01
1.9
8.30
8.1
3 5.25
3.7
11.31
8.2
# Points −− 4892 100 6135 98 7777
# Labs 22 5 28 3 32

Mean −− 72.82 −− 98.46 −− 134.4
SD
CV
1 −−
−−
3.90
5.4
2 −−
−−
5.40
5.5
3 −−
−−
8.80
6.6
# Points −− 213 −− 213 −− 212
# Labs 1 1 1

Mean 79.03 79.44 104.5 104.8 142.1 141.7
SD
CV
1 5.39
6.8
3.98
5.0
2 5.73
5.5
4.62
4.4
3 7.25
5.1
6.36
4.5
# Points 63 660 63 660 63 661
# Labs 2 2 2 2 2 2

Mean −− 83.91 −− −− −− 144.0
SD
CV
1 −−
−−
1.85
2.2
2 −−
−−
−−
−−
3 −−
−−
4.55
3.2
# Points −− 88 −− −− −− 90
# Labs 1 1
Mindray BS Series
Mean −− 103.4 −− 115.3 −− 156.4
SD
CV
1 −−
−−
2.63
2.5
2 −−
−−
19.28
16.7
3 −−
−−
24.33
15.6
# Points −− 120 −− 333 −− 332
# Labs 1 2 2
Mindray CL Series • Randox

Mean −− −− −− 110.4 −− 149.2
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.97
2.7
3 −−
−−
4.01
2.7
# Points −− −− −− 41 −− 43
# Labs 1 1

Mean −− 74.21 −− 104.4 −− 140.7
SD
CV
1 −−
−−
2.92
3.9
2 −−
−−
4.50
4.3
3 −−
−−
5.49
3.9
# Points −− 221 −− 2238 −− 2576
# Labs 2 8 10
Roche cobas 6000/8000/c 311 • Randox

Mean −− −− −− 101.3 −− 131.5
SD
CV
1 −−
−−
−−
−−
2 −−
−−
4.24
4.2
3 −−
−−
5.46
4.2
# Points −− −− −− 507 −− 517
# Labs 1 1

Mean −− −− −− 115.3 −− 157.5
SD
CV
1 −−
−−
−−
−−
2 −−
−−
3.32
2.9
3 −−
−−
3.58
2.3
# Points −− −− −− 293 −− 293
# Labs 1 1

Mean −− 81.25 −− 112.8 −− 155.6
SD
CV
1 −−
−−
3.75
4.6
2 −−
−−
6.62
5.9
3 −−
−−
6.30
4.0
# Points −− 574 −− 569 −− 577
# Labs 2 2 2


Mean −− −− −− 109.7 −− 142.0
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.19
2.0
3 −−
−−
2.63
1.9
# Points −− −− −− 248 −− 247
# Labs 1 1

Mean −− −− −− 98.61 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.17
2.2
3 −−
−−
−−
−−
# Points −− −− −− 23 −− −−
# Labs 1

Mean −− 79.46 96.00 105.2 126.0 135.7
SD
CV
1 −−
−−
2.52
3.2
2 3.00
3.1
16.56
15.7
3 4.00
3.2
13.76
10.1
# Points −− 323 35 471 32 777
# Labs 2 1 4 1 4

Mean −− 55.24 −− 74.60 −− 101.0
SD
CV
1 −−
−−
15.99
28.9
2 −−
−−
20.94
28.1
3 −−
−−
27.41
27.1
# Points −− 25 −− 25 −− 25
# Labs 1 1 1

Mean 77.30 79.03 99.10 103.3 127.1 133.9
SD
CV
1 2.57
3.3
4.26
5.4
2 2.12
2.1
5.32
5.2
3 1.21
1.0
10.54
7.9
# Points 35 3929 36 4054 27 1034
# Labs 5 12 5 12 1 4
Toshiba−TBA
Mean −− −− −− −− −− 139.9
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
3.40
2.4
# Points −− −− −− −− −− 84
# Labs 1
Mean −− 81.91 −− 109.0 −− 147.9
SD
CV
1 −−
−−
5.50
6.7
2 −−
−−
6.92
6.4
3 −−
−−
9.24
6.2
# Points −− 455 −− 462 −− 472
# Labs 3 3 3

Mean 79.34 79.98 103.2 104.7 138.7 140.4
SD
CV
1 4.70
5.9
5.66
7.1
2 5.27
5.1
8.10
7.7
3 9.00
6.5
11.22
8.0
# Points 141 14042 236 18728 239 18236
# Labs 9 54 14 75 8 74
Apolipoprotein B Immunonephelometric, end point mg/dL

Mean −− 38.25 −− −− −− 79.61
SD
CV
1 −−
−−
2.07
5.4
2 −−
−−
−−
−−
3 −−
−−
3.19
4.0
# Points −− 1017 −− −− −− 1015
# Labs 4 4

Mean −− 45.51 −− 64.99 −− 88.29
SD
CV
1 −−
−−
3.01
6.6
2 −−
−−
4.41
6.8
3 −−
−−
5.80
6.6
# Points −− 1051 −− 1005 −− 1005
# Labs 2 2 2

Apolipoprotein B Immunonephelometric, end point mg/dL

Mean −− −− −− 72.47 −− 98.68
SD
CV
1 −−
−−
−−
−−
2 −−
−−
3.75
5.2
3 −−
−−
3.11
3.1
# Points −− −− −− 174 −− 170
# Labs 1 1
Mindray BS Series
Mean −− 39.05 −− 84.73 −− −−
SD
CV
1 −−
−−
2.09
5.3
2 −−
−−
1.90
2.2
3 −−
−−
−−
−−
# Points −− 231 −− 228 −− −−
# Labs 1 1

Mean −− 41.65 −− 69.11 −− 85.07
SD
CV
1 −−
−−
4.37
10.5
2 −−
−−
8.32
12.0
3 −−
−−
7.34
8.6
# Points −− 2299 −− 1408 −− 2190
# Labs 7 4 7
Apolipoprotein B Immunonephelometric, kinetic mg/dL

Mean −− −− −− 71.48 −− 90.24
SD
CV
1 −−
−−
−−
−−
2 −−
−−
17.83
24.9
3 −−
−−
7.31
8.1
# Points −− −− −− 649 −− 651
# Labs 2 2

Mean −− −− −− 71.48 −− 90.24
SD
CV
1 −−
−−
−−
−−
2 −−
−−
17.83
24.9
3 −−
−−
7.31
8.1
# Points −− −− −− 649 −− 651
# Labs 2 2
Apolipoprotein B Immunoturbidimetric mg/dL

Mean 59.00 48.69 −− 65.76 102.0 89.05
SD
CV
1 1.00
1.7
4.26
8.7
2 −−
−−
2.91
4.4
3 1.00
1.0
4.08
4.6
# Points 19 1621 −− 1347 19 1646
# Labs 1 7 6 1 9

Mean 44.00 44.19 64.00 65.37 88.00 89.52
SD
CV
1 1.00
2.3
1.00
2.3
21.00
1.6
1.32
2.0
3 1.000
1.1
1.30
1.5
# Points 97 1557 98 1373 103 1511
# Labs 1 1 1 1 1 1

Mean −− 42.59 65.51 64.12 89.55 89.21
SD
CV
1 −−
−−
3.32
7.8
2 1.96
3.0
6.11
9.5
3 4.09
4.6
8.53
9.6
# Points −− 4993 101 8029 101 10150
# Labs 23 5 35 5 40

Mean −− 35.16 −− 51.39 −− 72.18
SD
CV
1 −−
−−
2.65
7.6
2 −−
−−
3.90
7.6
3 −−
−−
4.54
6.3
# Points −− 180 −− 180 −− 179
# Labs 1 1 1


Mean 33.50 34.24 49.97 50.71 69.46 70.32
SD
CV
1 2.95
8.8
1.93
5.6
2 4.04
8.1
2.54
5.0
3 5.56
8.0
3.03
4.3
# Points 62 654 63 657 63 657
# Labs 2 2 2 2 2 2

Mean −− −− −− 66.54 −− 85.51
SD
CV
1 −−
−−
−−
−−
2−−
−−
5.66
8.5
3 −−
−−
7.09
8.3
# Points −− −− −− 57 −− 57
# Labs 1 1

Mean −− 43.67 −− −− −− 82.33
SD
CV
1 −−
−−
9.00
20.6
2 −−
−−
−−
−−
3 −−
−−
5.24
6.4
# Points −− 89 −− −− −− 91
# Labs 1 1
Mindray BS Series
Mean −− −− −79418711 −− −79418686
SD
CV
1 −−
−−
−271146885
2697877846
995.0
2 −− 1460096398
−− 1838.5
3 −− 1460096399
−− 1838.5
# Points −− 99 −− 338 −− 338
# Labs 1 2 2

Mean −− −− −− 66.68 −− 92.07
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.13
3.2
3 −−
−−
2.96
3.2
# Points −− −− −− 38 −− 40
# Labs 1 1

Mean −− 39.71 −− 59.76 −− 80.88
SD
CV
1 −−
−−
1.45
3.7
2 −−
−−
4.46
7.5
3 −−
−−
5.16
6.4
# Points −− 225 −− 2368 −− 2798
# Labs 2 8 9

Mean −− −− −− 64.21 −− 91.97
SD
CV
1 −−
−−
−−
−−
2 −−
−−
8.29
12.9
3 −−
−−
12.11
13.2
# Points −− −− −− 380 −− 390
# Labs 1 1
Roche Hitachi Systems (International) • Beijing Bai Tai

Mean −− −− −− 60.15 −− 83.38
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.82
3.0
3 −−
−−
2.21
2.6
# Points −− −− −− 287 −− 287
# Labs 1 1

Mean −− 36.44 −− 58.40 −− 84.82
SD
CV
1 −−
−−
2.06
5.6
2 −−
−−
2.52
4.3
3 −−
−−
3.62
4.3
# Points −− 625 −− 626 −− 625
# Labs 2 2 2
Mean −− −− −− 62.08 −− 86.04
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.21
3.6
3 −−
−−
3.06
3.6
# Points −− −− −− 250 −− 249
# Labs 1 1


Mean −− −− −− 62.33 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.75
4.4
3 −−
−−
−−
−−
# Points −− −− −− 24 −− −−
# Labs 1

Mean −− 42.56 70.00 71.61 94.00 92.25
SD
CV
1 −−
−−
1.58
3.7
2 2.00
2.9
8.48
11.8
3 2.00
2.1
7.25
7.9
# Points −− 316 35 542 32 848
# Labs 2 1 3 1 4

Mean 38.14 42.78 56.47 62.22 79.48 85.42
SD
CV
1 1.71
4.5
3.70
8.7
2 2.15
3.8
4.65
7.5
3 1.64
2.1
5.04
5.9
# Points 38 1044 38 1039 29 1015
# Labs 5 8 5 8 1 3
Toshiba−TBA
Mean −− −− −− −− −− 83.50
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
3.43
4.1
# Points −− −− −− −− −− 84
# Labs 1
Mean −− 38.45 −− 57.79 −− 80.74
SD
CV
1 −−
−−
5.14
13.4
2 −−
−−
8.01
13.9
3 −−
−−
11.82
14.6
# Points −− 427 −− 429 −− 442
# Labs 3 3 3

Mean 41.28 −2266766 61.59 −1498990 85.69 −1257340
SD
CV
1 7.33 246676258
17.8 10882.3
2 6.90 200598861
11.2 13382.3
3 9.46 183722050
11.0 14612.0
# Points 216 11842 335 17907 347 21348
# Labs 9 53 14 76 11 82
AST (ASAT/GOT) Dinitrophenyl hydrazine U/L @ 37° C

Mean −− −− −− 97.37 −− 251.2
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.75
2.8
3 −−
−−
5.92
2.4
# Points −− −− −− 611 −− 610
# Labs 3 3

Mean −− 37.20 −− 98.22 −− 241.4
SD
CV
1 −−
−−
0.809
2.2
2 −−
−−
1.62
1.6
3 −−
−−
4.86
2.0
# Points −− 50 −− 50 −− 50
# Labs 1 1 1

Mean −− 37.20 −− 97.44 −− 250.5
SD
CV
1 −−
−−
0.809
2.2
2 −−
−−
2.69
2.8
3 −−
−−
6.40
2.6
# Points −− 50 −− 661 −− 660
# Labs 1 4 4

AST (ASAT/GOT) Enzymatic, colorimetric U/L @ 25° C

Mean −− 38.90 −− −− −− 234.1
SD
CV
1 −−
−−
2.51
6.5
2 −−
−−
−−
−−
3 −−
−−
4.49
1.9
# Points −− 165 −− −− −− 448
# Labs 3 3

Mean −− 31.27 −− 80.31 −− 196.9
SD
CV
1 −−
−−
0.592
1.9
2 −−
−−
1.04
1.3
3 −−
−−
3.61
1.8
# Points −− 84 −− 84 −− 84
# Labs 1 1 1

Mean −− 36.38 −− −− −− 219.1
SD
CV
1 −−
−−
0.738
2.0
2 −−
−−
−−
−−
3 −−
−−
4.58
2.1
# Points −− 300 −− −− −− 299
# Labs 1 1

Mean −− 36.35 −− 80.31 −− 224.9
SD
CV
1 −−
−−
2.85
7.9
2 −−
−−
1.04
1.3
3 −−
−−
12.52
5.6
# Points −− 549 −− 84 −− 831
# Labs 5 1 5

Mean −− 43.24 −− −− −− 235.5
SD
CV
1 −−
−−
2.00
4.6
2 −−
−−
−−
−−
3 −−
−−
7.76
3.3
# Points −− 75 −− −− −− 73
# Labs 1 1

Mean −− 37.56 −− 99.96 −− 232.2
SD
CV
1 −−
−−
2.96
7.9
2 −−
−−
9.44
9.4
3 −−
−−
2.58
1.1
# Points −− 85 −− 54 −− 157
# Labs 5 4 2
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH AST2 REF 04S90

Mean 42.83 41.64 111.7 109.3 −− −−
SD
CV
1 0.941
2.2
1.47
3.5
2
2.27
2.0
3.27
3.0
3 −−
−−
−−
−−
# Points 36 123 36 122 −− −−
# Labs 1 1 1 1

Mean 31.79 34.96 79.60 80.34 195.2 227.2
SD
CV
1 0.904
2.8
3.00
8.6
2 2.52
3.2
2.95
3.7
3 6.09
3.1
20.57
9.1
# Points 60 1777 62 689 58 2359
# Labs 2 6 2 2 2 8

Mean 39.33 37.69 101.2 98.77 −− 264.3
SD
CV
1 1.37
3.5
1.45
3.8
2 0.837
0.8
3.96
4.0
3 −−
−−
6.80
2.6
# Points 6 253 5 213 −− 48
# Labs 1 4 1 4 1
Fuji Dri−Chem Series • Fuji Dri−Chem GOT/AST−PIII, REF 9903140

Mean 39.00 37.88 99.00 96.31 −− −−
SD
CV
1 0.000
0.0
0.914
2.4
2
0.000
0.0
2.54
2.6
3 −−
−−
−−
−−
# Points 1 48 1 45 −− −−
# Labs 1 2 1 3


Mindray BS Series
Mean −− 39.53 −− 260.4 −− −−
SD
CV
1 −−
−−
0.746
1.9
2 −−
−−
4.42
1.7
3 −−
−−
−−
−−
# Points −− 222 −− 225 −− −−
# Labs 1 1

Mean 36.26 36.02 −− −− 236.8 238.0
SD
CV
1 1.13
3.1
1.11
3.1
2 −−
−−
−−
−−
3 6.78
2.9
7.12
3.0
# Points 69 745 −− −− 69 628
# Labs 2 2 2 2

Mean 34.98 36.47 95.44 97.72 240.4 242.4
SD
CV
1 0.650
1.9
1.58
4.3
2 1.62
1.7
3.51
3.6
3 3.83
1.6
8.61
3.5
# Points 14 267 14 267 14 267
# Labs 1 1 1 1 1 1

Mean −− 40.86 −− 106.9 −− 261.8
SD
CV
1 −−
−−
1.26
3.1
2 −−
−−
1.84
1.7
3 −−
−−
4.68
1.8
# Points −− 328 −− 326 −− 331
# Labs 2 2 2

Mean −− 35.00 −− −− −− 243.0
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− 1 −− −− −− 1
# Labs 1 1

Mean −− 39.20 −− −− −− 272.8
SD
CV
1 −−
−−
0.433
1.1
2 −−
−−
−−
−−
3 −−
−−
6.28
2.3
# Points −− 8 −− −− −− 8
# Labs 1 1

Mean −− 41.03 −− −− −− 290.2
SD
CV
1 −−
−−
1.90
4.6
2 −−
−−
−−
−−
3 −−
−−
13.95
4.8
# Points −− 321 −− −− −− 328
# Labs 1 1

Mean −− 40.84 −− 114.4 −− 301.9
SD
CV
1 −−
−−
1.23
3.0
2 −−
−−
3.85
3.4
3 −−
−−
6.23
2.1
# Points −− 55 −− 54 −− 54
# Labs 1 1 1

Mean −− 38.55 −− −− −− 270.5
SD
CV
1 −−
−−
0.878
2.3
2 −−
−−
−−
−−
3 −−
−−
6.02
2.2
# Points −− 160 −− −− −− 155
# Labs 1 1

Mean 36.11 37.09 92.35 112.9 220.1 240.2
SD
CV
1 4.04
11.2
3.28
8.8
2 14.54
15.7
53.89
47.7
3 21.78
9.9
25.69
10.7
# Points 186 4468 118 1995 141 4409
# Labs 8 30 6 19 5 22

AST (ASAT/GOT) Enzymatic, colorimetric−VITROS U/L @ 25° C

Mean −− 40.68 −− −− −− 286.9
SD
CV
1 −−
−−
1.31
3.2
2 −−
−−
−−
−−
3 −−
−−
10.30
3.6
# Points −− 472 −− −− −− 469
# Labs 2 2

Mean −− 40.99 −− −− −− 286.7
SD
CV
1 −−
−−
1.97
4.8
2 −−
−−
−−
−−
3 −−
−−
10.42
3.6
# Points −− 542 −− −− −− 534
# Labs 3 3

Mean −− 45.59 −− −− −− 280.5
SD
CV
1 −−
−−
1.18
2.6
2 −−
−−
−−
−−
3 −−
−−
7.68
2.7
# Points −− 22 −− −− −− 23
# Labs 1 1
Method Group • Enzymatic, colorimetric−VITROS

Mean −− 40.89 −− −− −− 285.2
SD
CV
1 −−
−−
2.02
5.0
2 −−
−−
−−
−−
3 −−
−−
9.97
3.5
# Points −− 712 −− −− −− 700
# Labs 5 5

Mean −− 32.50 −− −− −− 237.9
SD
CV
1 −−
−−
1.18
3.6
2 −−
−−
−−
−−
3 −−
−−
3.19
1.3
# Points −− 325 −− −− −− 326
# Labs 2 2

Mean 40.50 42.11 100.1 107.8 265.6 279.2
SD
CV
1 0.900
2.2
1.38
3.3
2 4.02
4.0
8.04
7.5
3 6.47
2.4
17.54
6.3
# Points 15 1205 35 1173 47 1400
# Labs 1 13 2 10 2 8

Mean −− 41.19 −− −− −− 295.6
SD
CV
1 −−
−−
0.688
1.7
2 −−
−−
−−
−−
3 −−
−−
6.88
2.3
# Points −− 305 −− −− −− 302
# Labs 2 2

Mean −− 45.32 −− 119.0 −− 305.1
SD
CV
1 −−
−−
1.62
3.6
2 −−
−−
3.25
2.7
3 −−
−−
11.94
3.9
# Points −− 1695 −− 1009 −− 1687
# Labs 17 13 17

Mean −− 43.74 −− 115.8 −− 298.9
SD
CV
1 −−
−−
2.62
6.0
2 −−
−−
7.52
6.5
3 −−
−−
15.98
5.3
# Points −− 1575 −− 1050 −− 1540
# Labs 16 11 16

Mean −− 42.44 −− 112.4 −− 298.5
SD
CV
1 −−
−−
1.51
3.6
2 −−
−−
3.20
2.8
3 −−
−−
10.91
3.7
# Points −− 3044 −− 2076 −− 3154
# Labs 21 15 21


Mean 42.63 42.93 112.4 111.9 287.5 293.8
SD
CV
1 0.845
2.0
1.39
3.2
2 1.93
1.7
2.56
2.3
3 6.78
2.4
11.26
3.8
# Points 59 1630 28 633 60 1714
# Labs 2 10 1 8 2 11

Mean −− 41.38 −− 107.6 −− 288.7
SD
CV
1 −−
−−
1.92
4.6
2 −−
−−
3.77
3.5
3 −−
−−
14.27
4.9
# Points −− 1745 −− 838 −− 1580
# Labs 11 6 10

Mean 42.63 41.84 107.2 105.9 274.3 285.4
SD
CV
1 2.18
5.1
1.83
4.4
2 3.52
3.3
3.58
3.4
3 11.68
4.3
18.12
6.4
# Points 208 1381 79 305 170 1265
# Labs 8 11 4 5 8 10

Mean 39.88 43.78 103.4 103.3 277.9 294.3
SD
CV
1 1.30
3.3
3.76
8.6
2 3.52
3.4
3.59
3.5
3 11.32
4.1
13.13
4.5
# Points 54 135 54 59 20 81
# Labs 3 5 3 3 2 3

Mean −− 46.61 −− −− −− 298.5
SD
CV
1 −−
−−
1.02
2.2
2 −−
−−
−−
−−
3 −−
−−
8.27
2.8
# Points −− 221 −− −− −− 194
# Labs 1 1

Mean −− 44.93 −− −− −− 288.3
SD
CV
1 −−
−−
0.814
1.8
2 −−
−−
−−
−−
3 −−
−−
7.71
2.7
# Points −− 60 −− −− −− 66
# Labs 1 1

Mean −− 43.12 −− −− −− 297.4
SD
CV
1 −−
−−
0.926
2.1
2 −−
−−
−−
−−
3 −−
−−
6.67
2.2
# Points −− 294 −− −− −− 302
# Labs 1 2

Mean 41.59 41.08 104.0 108.7 −− 278.6
SD
CV
1 1.07
2.6
1.58
3.9
2 3.49
3.4
5.23
4.8
3 −−
−−
11.54
4.1
# Points 75 1319 77 868 −− 872
# Labs 2 5 2 3 4

Mean −− 41.51 −− −− −− 298.3
SD
CV
1 −−
−−
0.985
2.4
2 −−
−−
−−
−−
3 −−
−−
7.86
2.6
# Points −− 87 −− −− −− 87
# Labs 1 1

Mean −− 42.47 −− 115.2 −− 292.6
SD
CV
1 −−
−−
1.81
4.3
2 −−
−−
4.28
3.7
3 −−
−−
11.68
4.0
# Points −− 4102 −− 769 −− 4006
# Labs 27 5 24


Mean −− 42.04 −− −− −− 291.2
SD
CV
1 −−
−−
2.24
5.3
2 −−
−−
−−
−−
3 −−
−−
10.13
3.5
# Points −− 1181 −− −− −− 1196
# Labs 6 6

Mean 41.05 40.99 109.2 111.5 287.3 292.2
SD
CV
1 2.00
4.9
1.69
4.1
2 3.91
3.6
4.37
3.9
3 10.33
3.6
11.22
3.8
# Points 308 16209 175 7235 247 15073
# Labs 16 106 8 52 14 94

Mean −− 41.18 −− 112.6 −− 292.4
SD
CV
1 −−
−−
1.51
3.7
2 −−
−−
4.16
3.7
3 −−
−−
10.73
3.7
# Points −− 19652 −− 7025 −− 19040
# Labs 95 32 90

Mean 40.13 40.76 99.73 107.9 −− 288.9
SD
CV
1 1.57
3.9
1.37
3.4
2 2.93
2.9
4.44
4.1
3 −−
−−
11.05
3.8
# Points 18 5748 23 2899 −− 6886
# Labs 1 39 1 13 40

Mean 41.31 41.37 110.5 112.0 285.2 290.5
SD
CV
1 1.78
4.3
1.80
4.4
2 3.87
3.5
5.00
4.5
3 10.87
3.8
11.66
4.0
# Points 730 7674 359 3551 660 7034
# Labs 32 60 15 30 26 50

Mean −− −− −− 112.0 −− 294.0
SD
CV
1 −−
−−
−−
−−
2 −−
−−
3.07
2.7
3 −−
−−
7.84
2.7
# Points −− −− −− 361 −− 359
# Labs 1 1

Mean −− 40.17 −− −− −− 282.0
SD
CV
1 −−
−−
0.875
2.2
2 −−
−−
−−
−−
3 −−
−−
5.91
2.1
# Points −− 107 −− −− −− 108
# Labs 1 1
Method Group • Enzymatic, colorimetric−VITROS

Mean 41.43 41.48 108.2 111.7 283.3 291.8
SD
CV
1 1.92
4.6
1.99
4.8
2 4.99
4.6
5.23
4.7
3 11.91
4.2
12.78
4.4
# Points 1467 68909 830 29851 1204 67828
# Labs 65 449 36 208 54 413
AST (ASAT/GOT) Other NADH depletion U/L @ 25° C

Mean −− 29.89 −− 1906 −− 183.4
SD
CV
1 −−
−−
1.95
6.5
2 −−
−−
3273
171.7
3 −−
−−
6.34
3.5
# Points −− 37 −− 37 −− 37
# Labs 1 1 1

Mean −− 36.97 −− −− −− 255.6
SD
CV
1 −−
−−
1.98
5.4
2 −−
−−
−−
−−
3 −−
−−
5.77
2.3
# Points −− 1258 −− −− −− 1126
# Labs 2 2


Roche cobas c 303/503 • Roche ASTP, REF 08056838
Mean 35.91 36.66 −− −− 263.1 257.3
SD
CV
1 1.01
2.8
1.72
4.7
2 −−
−−
−−
−−
3 2.86
1.1
5.55
2.2
# Points 98 2080 −− −− 92 1984
# Labs 2 2 2 2

Mean 35.91 36.54 −− 1906 263.1 255.9
SD
CV
1 1.01
2.8
1.94
5.3
2 −−
−−
3273
171.7
3 2.86
1.1
11.37
4.4
# Points 98 2117 −− 37 92 2021
# Labs 2 3 1 2 3

Mean 38.77 38.71 98.96 100.4 −− −−
SD
CV
1 1.53
3.9
1.16
3.0
2 3.51
3.5
2.69
2.7
3 −−
−−
−−
−−
# Points 26 67 26 66 −− −−
# Labs 1 1 1 1

Mean 38.77 38.71 98.96 100.4 −− −−
SD
CV
1 1.53
3.9
1.16
3.0
2 3.51
3.5
2.69
2.7
3 −−
−−
−−
−−
# Points 26 67 26 66 −− −−
# Labs 1 1 1 1

Mean 35.35 35.83 89.78 92.91 219.8 226.3
SD
CV
1 1.03
2.9
1.07
3.0
2 1.78
2.0
3.17
3.4
3 5.06
2.3
8.96
4.0
# Points 84 1741 83 1726 80 1659
# Labs 3 5 3 5 3 5
ERBA XL−640
Mean −− 34.61 −− 94.55 −− −−
SD
CV
1 −−
−−
1.07
3.1
2 −−
−−
2.55
2.7
3 −−
−−
−−
−−
# Points −− 55 −− 55 −− −−
# Labs 1 1

Mean −− 38.12 −− −− −− −−
SD
CV
1 −−
−−
0.795
2.1
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 66 −− −− −− −−
# Labs 1

Mean −− 43.06 −− 112.0 −− 276.6
SD
CV
1 −−
−−
1.45
3.4
2 −−
−−
2.18
1.9
3 −−
−−
4.30
1.6
# Points −− 3934 −− 3914 −− 3915
# Labs 3 3 3

Mean 35.35 40.75 89.78 106.1 219.8 261.7
SD
CV
1 1.03
2.9
3.62
8.9
2 1.78
2.0
9.19
8.7
3 5.06
2.3
23.81
9.1
# Points 84 5796 83 5695 80 5574
# Labs 3 10 3 9 3 8

AST (ASAT/GOT) UV with P5P U/L @ 37° C

Mean 37.95 37.37 −− 100.5 −− 264.5
SD
CV
1 0.580
1.5
1.14
3.1
2 −−
−−
2.55
2.5
3 −−
−−
3.70
1.4
# Points 22 5890 −− 229 −− 5655
# Labs 1 6 2 5

Mean −− −− −− 107.1 −− −−
SD
CV
1 −−
−−
−−
−−
2
−−
−−
2.93
2.7
3 −−
−−
−−
−−
# Points −− −− −− 109 −− −−
# Labs 1

Mean 34.44 35.52 87.01 93.93 −− 234.0
SD
CV
1 0.573
1.7
3.18
8.9
2 1.27
1.5
11.26
12.0
3 −−
−−
31.94
13.6
# Points 29 2241 29 1816 −− 1798
# Labs 1 12 1 8 11

Mean −− 38.91 −− 97.53 −− 240.6
SD
CV
1 −−
−−
1.51
3.9
2 −−
−−
4.03
4.1
3 −−
−−
11.79
4.9
# Points −− 204 −− 204 −− 203
# Labs 1 1 1

Mean −− −− −− 99.53 −− 246.5
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.71
1.7
3 −−
−−
6.92
2.8
# Points −− −− −− 167 −− 167
# Labs 1 1

Mean −− 35.56 −− −− −− −−
SD
CV
1 −−
−−
1.05
3.0
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 27 −− −− −− −−
# Labs 1

Mean −− 38.00 −− −− −− 248.0
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− 1 −− −− −− 1
# Labs 1 1

Mean −− −− −− 94.71 −− 235.5
SD
CV
1 −−
−−
−−
−−
2
−−
−−
3.26
3.4
3 −−
−−
8.14
3.5
# Points −− −− −− 106 −− 106
# Labs 1 1
RANDOX RX daytona
Mean 39.35 39.66 98.44 102.3 256.0 256.0
SD
CV
1 2.94
7.5
3.37
8.5
2 5.54
5.6
7.18
7.0
3 0.000
0.0
0.000
0.0
# Points 20 180 16 96 1 1
# Labs 1 1 1 2 1 1

Mean −− 36.03 −− 103.2 −− 265.5
SD
CV
1 −−
−−
1.35
3.8
2 −−
−−
2.30
2.2
3 −−
−−
4.92
1.9
# Points −− 1955 −− 1405 −− 1856
# Labs 7 5 7


Mean −− 36.30 −− −− −− 257.6
SD
CV
1 −−
−−
1.31
3.6
2 −−
−−
−−
−−
3 −−
−−
8.55
3.3
# Points −− 751 −− −− −− 739
# Labs 5 5

Mean 36.10 36.82 102.6 102.1 261.5 257.8
SD
CV
1 1.10
3.0
1.45
3.9
2 1.07
1.0
1.28
1.3
3 1.56
0.6
3.38
1.3
# Points 166 2137 172 2571 50 1269
# Labs 3 4 3 4 2 3

Mean −− 36.10 −− −− −− 271.1
SD
CV
1 −−
−−
1.28
3.5
2 −−
−−
−−
−−
3 −−
−−
6.20
2.3
# Points −− 130 −− −− −− 147
# Labs 1 1

Mean −− −− −− 101.7 −− 249.4
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.54
2.5
3 −−
−−
5.69
2.3
# Points −− −− −− 318 −− 318
# Labs 1 1

Mean −− 37.91 −− 100.2 −− 245.3
SD
CV
1 −−
−−
1.56
4.1
2 −−
−−
2.18
2.2
3 −−
−−
4.30
1.8
# Points −− 629 −− 477 −− 629
# Labs 2 2 2

Mean −− 38.23 −− 110.9 −− 285.9
SD
CV
1 −−
−−
2.06
5.4
2 −−
−−
3.29
3.0
3 −−
−−
10.11
3.5
# Points −− 427 −− 865 −− 851
# Labs 4 4 5

Mean −− 47.83 −− −− −− 275.1
SD
CV
1 −−
−−
2.78
5.8
2
−−
−−
−−
−−
3 −−
−−
6.43
2.3
# Points −− 142 −− −− −− 146
# Labs 1 1

Mean −− 41.02 −− −− −− 268.3
SD
CV
1 −−
−−
3.15
7.7
2 −−
−−
−−
−−
3 −−
−−
7.46
2.8
# Points −− 933 −− −− −− 919
# Labs 6 6

Mean 34.25 34.57 95.78 96.80 245.6 247.2
SD
CV
1 2.01
5.9
2.14
6.2
2 3.33
3.5
3.42
3.5
3 9.49
3.9
7.63
3.1
# Points 1694 99201 369 16879 1496 90668
# Labs 53 242 13 55 47 222

Mean 31.23 33.20 93.88 97.23 248.0 253.3
SD
CV
1 2.70
8.6
2.34
7.0
2 4.08
4.4
3.32
3.4
3 5.22
2.1
6.67
2.6
# Points 2967 228K 843 62213 2632 217K
# Labs 78 452 22 128 73 441


Mean −− 39.26 −− 104.8 −− 258.0
SD
CV
1 −−
−−
1.34
3.4
2 −−
−−
2.61
2.5
3 −−
−−
6.63
2.6
# Points −− 108 −− 107 −− 107
# Labs 1 1 1

Mean 32.52 33.78 95.34 97.53 247.3 251.9
SD
CV
1 2.95
9.1
2.49
7.4
2 4.73
5.0
4.10
4.2
3 7.29
2.9
8.42
3.3
# Points 4898 343K 1429 87456 4179 322K
# Labs 137 747 40 215 123 715
AST (ASAT/GOT) UV with P5P − IFCC Ref. Proc., Calibrated U/L @ 25° C
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH AST2, REF 04S90 (Factored, IFCC Correlated)
Mean 42.31 42.34 111.3 111.3 −− −−
SD
CV
1 3.39
8.0
3.22
7.6
2
7.48
6.7
7.09
6.4
3 −−
−−
−−
−−
# Points 19 21 19 21 −− −−
# Labs 1 1 1 1

Mean −− 2472 −− 6427 −− 15772
SD
CV
1 −−
−−
96.38
3.9
2 −−
−−
245.0
3.8
3 −−
−−
695.4
4.4
# Points −− 954 −− 1055 −− 1021
# Labs 1 1 1

Mean 42.31 2420 111.3 6304 −− 15772
SD
CV
1 3.39
8.0
365.6
15.1
7.48
6.7
2 907.1
14.4
3 −−
−−
695.4
4.4
# Points 19 975 19 1076 −− 1021
# Labs 1 2 1 2 1
Mean −− 36.76 −− 104.3 −− 264.0
SD
CV
1 −−
−−
1.06
2.9
2 −−
−−
1.80
1.7
3 −−
−−
3.78
1.4
# Points −− 8163 −− 7956 −− 8379
# Labs 14 13 12
Mean 41.86 40.83 109.2 105.4 −− −−
SD
CV
1 1.11
2.7
2.96
7.2
2
2.07
1.9
8.04
7.6
3 −−
−−
−−
−−
# Points 37 144 35 146 −− −−
# Labs 2 3 2 3
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c AST, REF 08P17

Mean −− 36.18 −− 91.73 −− −−
SD
CV
1 −−
−−
0.450
1.2
2−−
−−
1.70
1.9
3 −−
−−
−−
−−
# Points −− 91 −− 91 −− −−
# Labs 1 1
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c AST2, REF 04T86 (Factored, IFCC Correlated)
Mean 39.78 41.68 105.0 111.4 −− 267.4
SD
CV
1 1.49
3.7
2.92
7.0
2
4.00
3.8
6.22
5.6
3 −−
−−
3.13
1.2
# Points 52 426 80 400 −− 74
# Labs 2 8 3 7 2

Mean 36.00 36.95 −− 104.9 −− 263.2
SD
CV
1 0.760
2.1
1.36
3.7
2 −−
−−
2.47
2.4
3 −−
−−
4.93
1.9
# Points 8 7158 −− 3687 −− 6512
# Labs 1 19 9 15

Mean 38.75 38.33 106.3 105.4 264.0 261.1
SD
CV
1 1.20
3.1
2.11
5.5
2 2.58
2.4
3.62
3.4
3 10.34
3.9
15.19
5.8
# Points 174 7434 110 6565 170 7424
# Labs 5 22 2 18 5 22
Mindray BS Series
Mean −− 41.58 −− 109.0 −− 272.5
SD
CV
1 −−
−−
0.982
2.4
2 −−
−−
2.00
1.8
3 −−
−−
4.72
1.7
# Points −− 90 −− 222 −− 222
# Labs 1 1 1

Mean −− −− −− 98.05 −− 251.3
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.94
2.0
3 −−
−−
3.15
1.3
# Points −− −− −− 147 −− 147
# Labs 1 1

Mean 35.68 35.78 97.28 95.60 264.4 258.9
SD
CV
1 1.50
4.2
1.57
4.4
2 1.70
1.7
3.44
3.6
3 4.30
1.6
11.66
4.5
# Points 927 17740 31 3119 888 17710
# Labs 14 30 1 12 13 30

Mean −− 35.96 −− −− −− 238.3
SD
CV
1 −−
−−
0.977
2.7
2−−
−−
−−
−−
3 −−
−−
7.01
2.9
# Points −− 399 −− −− −− 396
# Labs 1 1

Mean 35.96 36.30 95.67 97.86 235.3 241.0
SD
CV
1 1.11
3.1
1.26
3.5
2
1.68
1.8
3.42
3.5
3 7.01
3.0
9.31
3.9
# Points 1007 19131 117 7991 1013 20018
# Labs 19 56 3 21 19 58

Mean 36.83 37.51 103.4 104.1 261.8 261.8
SD
CV
1 1.09
3.0
1.06
2.8
2 1.38
1.3
1.82
1.8
3 3.11
1.2
4.91
1.9
# Points 183 5801 71 3955 143 5682
# Labs 6 11 2 6 5 10
Roche cobas c 303/503 • 10 mL vial

Mean −− 35.93 −− −− −− 261.1
SD
CV
1 −−
−−
0.501
1.4
2 −−
−−
−−
−−
3 −−
−−
1.70
0.6
# Points −− 17 −− −− −− 18
# Labs 1 1

Mean −− 37.00 −− 101.7 −− 256.1
SD
CV
1 −−
−−
1.28
3.5
2 −−
−−
1.92
1.9
3 −−
−−
5.68
2.2
# Points −− 2017 −− 1935 −− 2089
# Labs 5 4 5

Roche cobas c 303/503 • Roche ASTP, REF 08056838
Mean 36.87 36.49 104.1 101.2 261.2 257.6
SD
CV
1 1.24
3.4
1.38
3.8
2 0.816
0.8
2.38
2.4
3 1.82
0.7
4.81
1.9
# Points 241 8948 49 890 104 8561
# Labs 6 31 2 7 3 28
Roche cobas c 303/503 • Roche ASTP2, REF 08104719

Mean 37.01 36.99 −− −− 262.0 265.4
SD
CV
1 0.399
1.1
0.540
1.5
2 −−
−−
−−
−−
3 0.784
0.3
4.66
1.8
# Points 14 54 −− −− 14 61
# Labs 1 3 1 3

Mean 35.40 35.21 102.0 101.1 −− −−
SD
CV
1 1.20
3.4
1.43
4.1
2 1.80
1.8
2.24
2.2
3 −−
−−
−−
−−
# Points 100 1159 101 1173 −− −−
# Labs 1 1 1 1

Mean −− 35.36 −− −− −− 264.1
SD
CV
1 −−
−−
0.593
1.7
2 −−
−−
−−
−−
3 −−
−−
1.69
0.6
# Points −− 36 −− −− −− 36
# Labs 1 1

Mean 35.43 35.58 −− −− 228.3 241.9
SD
CV
1 0.960
2.7
1.17
3.3
2 −−
−−
−−
−−
3 5.64
2.5
16.76
6.9
# Points 37 2111 −− −− 38 2089
# Labs 1 5 1 5
Mean −− −− −− 100.8 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.47
1.5
3 −−
−−
−−
−−
# Points −− −− −− 6 −− −−
# Labs 2

Mean −− 40.74 107.6 110.4 −− 269.2
SD
CV
1 −−
−−
2.24
5.5
2 2.87
2.7
4.34
3.9
3 −−
−−
8.57
3.2
# Points −− 923 22 1914 −− 1889
# Labs 4 1 7 5

Mean 43.14 43.29 103.9 106.5 −− 254.3
SD
CV
1 2.29
5.3
2.01
4.7
2.91
2.8
2 3.64
3.4
3 −−
−−
8.62
3.4
# Points 37 466 68 578 −− 49
# Labs 1 3 2 3 1

Mean 38.68 39.88 105.4 106.7 258.2 267.4
SD
CV
1 2.08
5.4
2.35
5.9
2 3.21
3.0
3.57
3.3
3 12.93
5.0
8.81
3.3
# Points 203 13428 88 6437 234 11501
# Labs 6 38 3 28 7 35

Mean −− 40.88 −− 105.6 −− 261.8
SD
CV
1 −−
−−
1.30
3.2
2 −−
−−
4.30
4.1
3 −−
−−
6.28
2.4
# Points −− 5754 −− 5180 −− 722
# Labs 9 7 3

Siemens Atellica CH Analyzer • Siemens Atellica CH AST, REF 11097607 (Factored, IFCC Correlated)
Mean 39.93 40.66 103.0 103.3 −− 262.9
SD
CV
1 1.65
4.1
1.79
4.4
2
3.81
3.7
4.64
4.5
3 −−
−−
9.70
3.7
# Points 376 5202 376 2113 −− 3878
# Labs 9 22 9 16 13
Siemens Atellica CH Analyzer • Siemens Atellica CH ASTPLc, REF 11097639

Mean −− 41.04 102.5 106.0 265.5 271.1
SD
CV
1 −−
−−
1.74
4.2
2
3.55
3.5
2.67
2.5
3 8.49
3.2
4.61
1.7
# Points −− 132 8 85 8 561
# Labs 4 1 3 1 5

Mean 33.97 35.19 94.27 95.82 243.4 246.4
SD
CV
1 1.64
4.8
2.55
7.2
2 2.23
2.4
3.03
3.2
3 5.41
2.2
6.71
2.7
# Points 114 6366 52 2645 117 4990
# Labs 4 20 2 12 4 12

Mean 31.65 33.84 97.45 98.27 251.6 251.8
SD
CV
1 2.40
7.6
2.24
6.6
2 1.97
2.0
2.81
2.9
3 1.29
0.5
7.12
2.8
# Points 219 20240 223 14011 11 8136
# Labs 10 30 10 16 2 19

Mean −− −− 107.8 107.6 −− −−
SD
CV
1 −−
−−
−−
−−
2 3.39
3.1
3.33
3.1
3 −−
−−
−−
−−
# Points −− −− 20 28 −− −−
# Labs 1 1

Mean −− −− −− 106.5 −− 283.7
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.74
2.6
3 −−
−−
10.53
3.7
# Points −− −− −− 83 −− 92
# Labs 2 2

Mean 36.52 36.86 101.9 102.1 251.4 256.4
SD
CV
1 2.57
7.0
2.76
7.5
2
4.74
4.7
5.12
5.0
3 15.24
6.1
12.92
5.0
# Points 3729 134K 1451 71357 2740 111K
# Labs 88 344 45 201 61 289
AST (ASAT/GOT) UV with P5P−VITROS U/L @ 25° C

Mean −− 41.25 −− −− −− 297.4
SD
CV
1 −−
−−
0.868
2.1
2 −−
−−
−−
−−
3 −−
−−
6.53
2.2
# Points −− 57 −− −− −− 57
# Labs 1 1

Mean −− 41.25 −− −− −− 297.4
SD
CV
1 −−
−−
0.868
2.1
2 −−
−−
−−
−−
3 −−
−−
6.53
2.2
# Points −− 57 −− −− −− 57
# Labs 1 1


Mean −− 35.77 −− 110.1 −− 283.2
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
3.45
3.1
3 −−
−−
10.28
3.6
# Points −− 1 −− 47 −− 47
# Labs 1 2 2

Mean −− 45.42 −− −− −− 309.2
SD
CV
1 −−
−−
1.09
2.4
2 −−
−−
−−
−−
3 −−
−−
11.43
3.7
# Points −− 262 −− −− −− 266
# Labs 1 1

Mean −− 45.40 −− −− −− 307.1
SD
CV
1 −−
−−
1.44
3.2
2 −−
−−
−−
−−
3 −−
−−
9.29
3.0
# Points −− 475 −− −− −− 469
# Labs 2 2

Mean −− 43.86 −− −− −− 300.9
SD
CV
1 −−
−−
0.786
1.8
2 −−
−−
−−
−−
3 −−
−−
6.99
2.3
# Points −− 60 −− −− −− 60
# Labs 2 2

Mean 44.58 44.58 −− −− 289.0 289.0
SD
CV
1 1.25
2.8
1.25
2.8
2 −−
−−
−−
−−
3 6.52
2.3
6.52
2.3
# Points 27 27 −− −− 20 20
# Labs 1 1 1 1

Mean 42.36 42.36 −− −− 277.0 277.0
SD
CV
1 0.776
1.8
0.776
1.8
2 −−
−−
−−
−−
3 14.66
5.3
14.66
5.3
# Points 3 3 −− −− 3 3
# Labs 1 1 1 1

Mean 39.67 39.79 −− −− 280.2 283.5
SD
CV
1 1.28
3.2
1.63
4.1
2 −−
−−
−−
−−
3 5.88
2.1
8.92
3.1
# Points 38 134 −− −− 37 131
# Labs 1 1 1 1

Mean −− 43.10 −− −− −− 309.2
SD
CV
1 −−
−−
0.141
0.3
2 −−
−−
−−
−−
3 −−
−−
3.18
1.0
# Points −− 2 −− −− −− 2
# Labs 1 1

Mean 42.07 41.43 113.1 113.5 289.1 295.0
SD
CV
1 1.51
3.6
1.56
3.8
2 2.59
2.3
4.11
3.6
3 6.70
2.3
11.36
3.9
# Points 35 1452 3 864 28 974
# Labs 2 10 1 4 1 7

Mean −− 40.86 −− 111.7 −− 291.1
SD
CV
1 −−
−−
1.55
3.8
2 −−
−−
2.65
2.4
3 −−
−−
8.49
2.9
# Points −− 2009 −− 857 −− 1100
# Labs 13 4 8


Mean −− 41.98 −− 117.6 −− 285.1
SD
CV
1 −−
−−
1.87
4.5
2 −−
−−
2.26
1.9
3 −−
−−
4.98
1.7
# Points −− 360 −− 155 −− 200
# Labs 5 2 3

Mean 42.31 42.39 −− −− 289.1 289.3
SD
CV
1 1.02
2.4
1.05
2.5
2 −−
−−
−−
−−
3 7.49
2.6
7.33
2.5
# Points 20 21 −− −− 20 21
# Labs 1 1 1 1

Mean −− 41.40 −− −− −− 291.7
SD
CV
1 −−
−−
1.15
2.8
2 −−
−−
−−
−−
3 −−
−−
6.53
2.2
# Points −− 129 −− −− −− 127
# Labs 2 2

Mean 41.93 41.83 113.1 113.0 285.7 295.2
SD
CV
1 2.19
5.2
2.21
5.3
2 2.59
2.3
3.76
3.3
3 8.01
2.8
12.08
4.1
# Points 123 4935 3 1923 108 3420
# Labs 6 41 1 12 5 32
AST (ASAT/GOT) UV without P5P U/L @ 22° C

Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH AST REF 7D81
Mean 36.15 36.17 90.92 91.52 −− −−
SD
CV
1 0.555
1.5
0.606
1.7
2
1.19
1.3
1.69
1.8
3 −−
−−
−−
−−
# Points 13 170 13 170 −− −−
# Labs 1 1 1 1

Mean −− 38.32 −− −− −− 247.1
SD
CV
1 −−
−−
1.83
4.8
2 −−
−−
−−
−−
3 −−
−−
6.04
2.4
# Points −− 472 −− −− −− 469
# Labs 2 2

Mean 36.15 37.75 90.92 91.52 −− 247.1
SD
CV
1 0.555
1.5
1.86
4.9
2 1.19
1.3
1.69
1.8
3 −−
−−
6.04
2.4
# Points 13 642 13 170 −− 469
# Labs 1 3 1 1 2

Mean 40.00 41.56 97.00 97.68 −− 223.0
SD
CV
1 0.000
0.0
1.25
3.0
2 0.000
0.0
2.83
2.9
3 −−
−−
2.92
1.3
# Points 1 27 1 19 −− 5
# Labs 1 1 1 1 1

Mean −− 36.48 −− −− −− 233.7
SD
CV
1 −−
−−
6.41
17.6
2 −−
−−
−−
−−
3 −−
−−
5.65
2.4
# Points −− 125 −− −− −− 122
# Labs 1 1


Mean −− 34.02 −− 86.59 −− 202.3
SD
CV
1 −−
−−
3.23
9.5
2 −−
−−
4.66
5.4
3 −−
−−
12.54
6.2
# Points −− 453 −− 112 −− 416
# Labs 2 1 2

Mean −− 37.08 −− −− −− 227.2
SD
CV
1 −−
−−
1.07
2.9
2 −−
−−
−−
−−
3 −−
−−
5.16
2.3
# Points −− 458 −− −− −− 471
# Labs 1 1
ILab Series
Mean 39.91 40.37 96.55 96.85 −− −−
SD
CV
1 1.45
3.6
1.35
3.3
2 2.66
2.8
2.61
2.7
3 −−
−−
−−
−−
# Points 11 48 11 48 −− −−
# Labs 1 1 1 1

Mean −− 2236 −− −− −− 14753
SD
CV
1 −−
−−
61.28
2.7
−−
−−
2 −−
−−
3 −−
−−
352.4
2.4
# Points −− 34 −− −− −− 34
# Labs 1 1

Mean 39.92 36.02 96.58 90.52 −− 217.8
SD
CV
1 1.38
3.5
3.62
10.1
2 2.54
2.6
6.49
7.2
3 −−
−−
15.81
7.3
# Points 12 1111 12 179 −− 1014
# Labs 2 6 2 3 5

Mean −− 35.29 −− 94.61 −− −−
SD
CV
1 −−
−−
0.613
1.7
2 −−
−−
0.876
0.9
3 −−
−−
−−
−−
# Points −− 84 −− 77 −− −−
# Labs 1 1

Mean 32.00 32.20 −− −− 201.0 202.4
SD
CV
1 1.00
3.1
0.802
2.5
2 −−
−−
−−
−−
3 3.00
1.5
3.71
1.8
# Points 22 402 −− −− 22 382
# Labs 1 1 1 1

Mean 32.00 32.74 −− 94.61 201.0 202.4
SD
CV
1 1.00
3.1
1.40
4.3
2 −−
−−
0.876
0.9
3 3.00
1.5
3.71
1.8
# Points 22 486 −− 77 22 382
# Labs 1 2 1 1 1

Mean 36.02 35.94 93.53 94.35 230.6 233.0
SD
CV
1 0.890
2.5
1.07
3.0
2 2.78
3.0
2.80
3.0
3 5.86
2.5
6.64
2.9
# Points 761 49110 245 24116 772 48943
# Labs 22 160 9 97 22 141


Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH AST2 REF 04S90
Mean 42.00 41.68 110.2 109.0 −− −−
SD
CV
1 1.04
2.5
2.50
6.0
2
2.76
2.5
6.28
5.8
3 −−
−−
−−
−−
# Points 190 354 189 352 −− −−
# Labs 8 8 8 8
Mean 40.28 37.12 89.83 90.69 225.5 229.9
SD
CV
1 2.13
5.3
3.21
8.7
2
1.57
1.7
2.68
3.0
3 4.15
1.8
17.45
7.6
# Points 250 3537 61 2222 35 2287
# Labs 10 14 6 6 5 7
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c AST, REF 08P17

Mean −− 38.55 −− 101.0 −− −−
SD
CV
1 −−
−−
3.60
9.3
2 −−
−−
10.99
10.9
3 −−
−−
−−
−−
# Points −− 135 −− 136 −− −−
# Labs 2 2
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c AST2 REF 04T86

Mean 39.52 40.48 110.4 107.2 −− 37.00
SD
CV
1 3.87
9.8
3.26
8.0
2 3.43
3.1
8.08
7.5
3 −−
−−
0.000
0.0
# Points 54 220 31 187 −− 1
# Labs 3 4 2 4 1
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c AST2, REF 04T86 (Factored, IFCC Correlated)
Mean 40.70 40.81 106.5 102.0 260.7 266.3
SD
CV
1 1.61
4.0
1.86
4.6
2 3.80
3.6
7.33
7.2
3 6.92
2.7
12.57
4.7
# Points 398 1931 316 1579 223 1210
# Labs 14 18 14 16 9 12

Mean 35.28 35.47 −− 95.49 224.4 228.5
SD
CV
1 0.884
2.5
0.820
2.3
2 −−
−−
1.63
1.7
3 1.78
0.8
4.81
2.1
# Points 67 839 −− 144 66 840
# Labs 2 5 2 2 5

Mean −− 39.01 −− 99.94 −− 239.9
SD
CV
1 −−
−−
0.971
2.5
2 −−
−−
2.51
2.5
3 −−
−−
8.86
3.7
# Points −− 248 −− 270 −− 247
# Labs 1 1 1

Mean 36.56 36.63 96.73 96.05 235.5 237.6
SD
CV
1 0.830
2.3
0.799
2.2
2 4.13
4.3
2.55
2.7
3 4.07
1.7
4.50
1.9
# Points 26 383 26 423 26 426
# Labs 1 1 1 1 1 1

Mean −− −− −− 99.77 −− 248.9
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.42
2.4
3 −−
−−
5.54
2.2
# Points −− −− −− 567 −− 566
# Labs 2 2

Mean 32.09 31.73 80.98 82.87 198.7 202.8
SD
CV
1 1.23
3.8
1.20
3.8
2 4.12
5.1
3.27
3.9
3 7.03
3.5
7.12
3.5
# Points 1636 59000 1353 31064 705 53643
# Labs 56 187 46 105 25 147


Mean 34.71 34.36 85.37 86.37 −− −−
SD
CV
1 0.410
1.2
0.496
1.4
2 1.51
1.8
1.71
2.0
3 −−
−−
−−
−−
# Points 23 266 23 196 −− −−
# Labs 1 1 1 1

Mean 39.74 39.96 102.3 104.6 252.1 256.3
SD
CV
1 0.922
2.3
1.61
4.0
2 2.42
2.4
3.92
3.8
3 6.03
2.4
10.33
4.0
# Points 87 30876 291 36694 292 38072
# Labs 3 81 8 95 8 101

Mean −− 41.87 −− −− −− 275.0
SD
CV
1 −−
−−
1.02
2.4
2 −−
−−
−−
−−
3 −−
−−
14.40
5.2
# Points −− 217 −− −− −− 217
# Labs 1 1

Mean 37.67 37.00 94.67 94.52 235.2 230.6
SD
CV
1 1.50
4.0
1.83
4.9
2 2.87
3.0
3.86
4.1
3 7.60
3.2
9.90
4.3
# Points 63 657 64 658 63 657
# Labs 2 2 2 2 2 2

Mean −− 38.99 −− −− −− 257.1
SD
CV
1 −−
−−
0.876
2.2
2 −−
−−
−−
−−
3 −−
−−
2.86
1.1
# Points −− 724 −− −− −− 724
# Labs 1 1

Mean −− −− 95.20 92.50 233.8 229.1
SD
CV
1 −−
−−
−−
−−
2 0.840
0.9
5.85
6.3
3 0.960
0.4
14.88
6.5
# Points −− −− 5 730 4 730
# Labs 1 2 1 2

Mean 37.57 37.99 −− 96.90 221.3 229.1
SD
CV
1 1.04
2.8
1.42
3.7
2 −−
−−
4.04
4.2
3 5.25
2.4
7.46
3.3
# Points 65 10248 −− 2270 67 9833
# Labs 2 32 8 2 30
Dirui CS Series
Mean −− 38.45 −− 96.65 −− 234.8
SD
CV
1 −−
−−
1.06
2.8
2 −−
−−
3.83
4.0
3 −−
−−
12.10
5.2
# Points −− 869 −− 861 −− 864
# Labs 2 2 2

Mean −− −− 96.45 96.18 236.5 237.9
SD
CV
1 −−
−−
−−
−−
2 2.87
3.0
3.14
3.3
3 6.26
2.6
6.52
2.7
# Points −− −− 44 251 42 252
# Labs 3 3 3 3

Mean 37.63 39.22 95.30 102.8 265.4 255.5
SD
CV
1 3.33
8.9
2.87
7.3
2 5.51
5.8
9.16
8.9
3 14.36
5.4
9.29
3.6
# Points 54 707 40 536 5 44
# Labs 3 4 3 4 1 2


Mean −− 38.62 −− 96.35 −− 243.3
SD
CV
1 −−
−−
2.30
5.9
2 −−
−−
3.83
4.0
3 −−
−−
13.78
5.7
# Points −− 4800 −− 2901 −− 4791
# Labs 12 7 12

Mean −− 38.94 −− −− −− 252.1
SD
CV
1 −−
−−
0.971
2.5
2 −−
−−
−−
−−
3 −−
−−
6.44
2.6
# Points −− 90 −− −− −− 92
# Labs 1 1

Mean −− −− 106.1 99.75 −− 252.2
SD
CV
1 −−
−−
−−
−−
2
1.22
1.1
4.35
4.4
3 −−
−−
9.80
3.9
# Points −− −− 23 184 −− 171
# Labs 1 1 1

Mean −− 40.80 −− 104.6 −− 259.0
SD
CV
1 −−
−−
2.29
5.6
2 −−
−−
6.72
6.4
3 −−
−−
15.58
6.0
# Points −− 247 −− 209 −− 240
# Labs 2 1 2
Mindray BS Series
Mean 38.74 38.69 99.29 99.01 245.9 241.4
SD
CV
1 1.20
3.1
1.03
2.7
2 3.58
3.6
2.67
2.7
3 5.65
2.3
7.17
3.0
# Points 21 155 21 155 21 155
# Labs 1 1 1 1 1 1
Mindray CL Series
Mean −− −− −− 109.6 −− 271.8
SD
CV
1 −−
−−
−−
−−
2 −−
−−
4.07
3.7
3 −−
−−
9.84
3.6
# Points −− −− −− 91 −− 92
# Labs 1 1

Mean −− −− −− 97.37 −− 242.9
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.83
2.9
3 −−
−−
6.31
2.6
# Points −− −− −− 251 −− 251
# Labs 2 2
RANDOX RX imola
Mean 40.02 39.54 102.1 100.8 −− −−
SD
CV
1 0.744
1.9
1.25
3.2
2 1.80
1.8
2.69
2.7
3 −−
−−
−−
−−
# Points 26 226 24 194 −− −−
# Labs 1 1 1 1

Mean 36.09 36.27 −− 96.79 233.1 241.3
SD
CV
1 1.22
3.4
1.39
3.8
2 −−
−−
3.27
3.4
3 9.03
3.9
8.67
3.6
# Points 410 30524 −− 18490 413 32972
# Labs 7 85 54 7 90

Mean 36.31 36.26 94.32 97.66 236.8 240.5
SD
CV
1 1.01
2.8
1.34
3.7
2
2.96
3.1
3.37
3.5
3 4.80
2.0
7.87
3.3
# Points 235 5260 147 2747 206 5046
# Labs 7 13 5 9 6 12

Mean −− 37.12 −− 102.7 −− 259.2
SD
CV
1 −−
−−
1.62
4.4
2 −−
−−
1.02
1.0
3 −−
−−
2.68
1.0
# Points −− 2320 −− 2308 −− 2341
# Labs 4 4 4

Mean 37.38 36.39 99.79 97.22 247.7 239.8
SD
CV
1 3.07
8.2
2.05
5.6
2 2.81
2.8
3.21
3.3
3 17.43
7.0
9.94
4.1
# Points 113 729 113 913 113 1007
# Labs 3 4 3 4 3 5

Mean 37.00 35.96 99.00 96.78 245.0 239.9
SD
CV
1 1.00
2.7
1.20
3.3
2 1.00
1.0
2.09
2.2
3 2.00
0.8
6.57
2.7
# Points 33 1323 33 744 32 1490
# Labs 1 6 1 2 1 5

Mean 34.00 35.12 −− −− 228.0 227.2
SD
CV
1 1.00
2.9
1.55
4.4
2 −−
−−
−−
−−
3 6.00
2.6
7.32
3.2
# Points 19 198 −− −− 19 196
# Labs 1 1 1 1

Mean 36.55 35.82 96.06 92.07 235.5 226.5
SD
CV
1 2.80
7.7
2.48
6.9
2 5.33
5.5
7.06
7.7
3 6.78
2.9
11.25
5.0
# Points 31 844 31 837 31 741
# Labs 1 4 1 4 1 3
Mean −− 38.08 −− 98.85 −− 242.9
SD
CV
1 −−
−−
1.29
3.4
2 −−
−−
5.55
5.6
3 −−
−−
14.73
6.1
# Points −− 272 −− 610 −− 607
# Labs 1 2 2

Mean −− 40.60 −− −− −− 260.1
SD
CV
1 −−
−−
1.26
3.1
2 −−
−−
−−
−−
3 −−
−−
6.23
2.4
# Points −− 278 −− −− −− 281
# Labs 1 1

Mean −− −− −− 92.41 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.02
2.2
3 −−
−−
−−
−−
# Points −− −− −− 24 −− −−
# Labs 1

Mean 43.03 42.75 102.0 107.8 253.0 263.9
SD
CV
1 1.33
3.1
2.26
5.3
2 2.17
2.1
5.08
4.7
3 3.62
1.4
7.65
2.9
# Points 86 7894 22 2789 87 6638
# Labs 3 21 1 13 3 19
Siemens ADVIA Chemistry Systems • Abbott ARCH AST REF 7D81

Mean −− 39.79 −− 98.96 −− 238.7
SD
CV
1 −−
−−
2.08
5.2
−−
−−
2
3.80
3.8
3 −−
−−
9.87
4.1
# Points −− 433 −− 432 −− 434
# Labs 1 1 1

Mean −− 41.72 −− 108.0 −− 268.3
SD
CV
1 −−
−−
1.38
3.3
2
−−
−−
2.93
2.7
3 −−
−−
6.36
2.4
# Points −− 1663 −− 927 −− 1668
# Labs 4 4 4
Siemens ADVIA Chemistry Systems • Fosun Diagnostics

Mean −− −− 96.74 100.5 244.2 251.7
SD
CV
1 −−
−−
−−
−−
2 3.54
3.7
4.75
4.7
3 8.61
3.5
13.41
5.3
# Points −− −− 35 558 32 544
# Labs 1 2 1 2

Mean 40.50 40.90 104.8 108.6 254.2 265.8
SD
CV
1 0.577
1.4
1.79
4.4
2 1.30
1.2
4.06
3.7
3 6.14
2.4
8.53
3.2
# Points 4 5432 5 3225 5 4943
# Labs 2 12 2 11 2 12

Mean −− 37.10 −− −− −− 253.6
SD
CV
1 −−
−−
3.37
9.1
2 −−
−−
−−
−−
3 −−
−−
7.72
3.0
# Points −− 236 −− −− −− 233
# Labs 2 2
Toshiba−TBA
Mean −− −− −− −− −− 262.5
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
6.20
2.4
# Points −− −− −− −− −− 71
# Labs 1

Mean −− 43.09 −− 110.0 −− 271.6
SD
CV
1 −−
−−
2.22
5.2
2 −−
−−
2.66
2.4
3 −−
−−
5.87
2.2
# Points −− 397 −− 450 −− 466
# Labs 3 3 3

Mean 35.89 36.16 92.05 96.09 229.9 234.0
SD
CV
1 3.67
10.2
3.54
9.8
2 11.29
12.3
9.02
9.4
3 20.35
8.8
21.94
9.4
# Points 4652 224K 3142 143K 3259 225K
# Labs 154 703 121 491 107 648

Mean −− 34.02 −− −− −− 210.4
SD
CV
1 −−
−−
2.98
8.7
2
−−
−−
−−
−−
3 −−
−−
4.64
2.2
# Points −− 176 −− −− −− 172
# Labs 1 1

Mean −− 34.02 −− −− −− 210.4
SD
CV
1 −−
−−
2.98
8.7
2 −−
−−
−−
−−
3 −−
−−
4.64
2.2
# Points −− 176 −− −− −− 172
# Labs 1 1
AST (ASAT/GOT) UV without P5P U/L

Mean −− 41.00 −− 246.0 −− −−
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
0.000
0.0
3 −−
−−
−−
−−
# Points −− 1 −− 1 −− −−
# Labs 1 1

Mean −− 41.00 −− 246.0 −− −−
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
0.000
0.0
3 −−
−−
−−
−−
# Points −− 1 −− 1 −− −−
# Labs 1 1
Beta Globulin Agarose Gel %

Interlab G26
Mean −− 9.82 −− 10.85 −− 12.73
SD
CV
1 −−
−−
0.540
5.5
2 −−
−−
0.730
6.7
3 −−
−−
0.840
6.6
# Points −− 4 −− 4 −− 4
# Labs 1 1 1

Mean −− 9.82 −− 10.85 −− 12.73
SD
CV
1 −−
−−
0.540
5.5
2 −−
−−
0.730
6.7
3 −−
−−
0.840
6.6
# Points −− 4 −− 4 −− 4
# Labs 1 1 1
Beta Globulin REP Gel %

Helena REP
Mean −− −− −− 10.96 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.895
8.2
3 −−
−−
−−
−−
# Points −− −− −− 87 −− −−
# Labs 1

Mean −− −− −− 10.96 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.895
8.2
3 −−
−−
−−
−−
# Points −− −− −− 87 −− −−
# Labs 1
Bicarbonate Enzymatic mEq/L

Mean 15.75 15.83 −− 18.50 24.54 24.94
SD
CV
1 0.786
5.0
0.775
4.9
2 −−
−−
1.46
7.9
3 1.37
5.6
1.20
4.8
# Points 48 701 −− 57 48 695
# Labs 1 3 2 1 3

Mean −− 16.46 −− 19.59 −− 26.60
SD
CV
1 −−
−−
1.35
8.2
2 −−
−−
1.30
6.7
3 −−
−−
2.01
7.5
# Points −− 1629 −− 945 −− 1330
# Labs 11 8 8

Mean −− 14.92 −− −− −− 22.81
SD
CV
1 −−
−−
1.03
6.9
2 −−
−−
−−
−−
3 −−
−−
1.35
5.9
# Points −− 621 −− −− −− 621
# Labs 2 2
Bicarbonate Enzymatic mEq/L

Mean 17.41 16.80 −− −− 26.80 25.71
SD
CV
1 1.44
8.2
0.980
5.8
2 −−
−−
−−
−−
3 2.24
8.4
1.53
6.0
# Points 88 979 −− −− 88 837
# Labs 2 3 2 3

Mean −− 17.21 −− 20.27 −− 25.32
SD
CV
1 −−
−−
1.50
8.7
2 −−
−−
1.12
5.5
3 −−
−−
2.12
8.4
# Points −− 5993 −− 4968 −− 6111
# Labs 6 4 6

Mean 17.70 17.99 −− −− 26.10 26.67
SD
CV
1 1.30
7.3
1.39
7.7
2 −−
−−
−−
−−
3 1.70
6.5
1.92
7.2
# Points 23 595 −− −− 26 638
# Labs 1 1 1 1
Toshiba−TBA • DiaSys Diagnostic Systems

Mean −− 18.07 −− −− −− 27.55
SD
CV
1 −−
−−
0.544
3.0
2 −−
−−
−−
−−
3 −−
−−
0.757
2.7
# Points −− 177 −− −− −− 178
# Labs 1 1

Mean 17.73 17.63 −− 20.17 26.78 26.39
SD
CV
1 1.82
10.2
1.94
11.0
2 −−
−−
1.21
6.0
3 2.36
8.8
2.57
9.7
# Points 226 14035 −− 6024 233 13841
# Labs 6 32 15 6 29
Bicarbonate ISE indirect mEq/L

Mean −− 16.04 −− 18.68 −− 24.81
SD
CV
1 −−
−−
1.17
7.3
2 −−
−−
1.30
7.0
3 −−
−−
1.65
6.7
# Points −− 835 −− 840 −− 831
# Labs 1 1 1
Method Group • ISE indirect

Mean −− 16.04 −− 18.68 −− 24.81
SD
CV
1 −−
−−
1.17
7.3
2 −−
−−
1.30
7.0
3 −−
−−
1.65
6.7
# Points −− 835 −− 840 −− 831
# Labs 1 1 1
Bilirubin, Direct/BC (DBIL) Calculated mg/dL

Mean −− 0.158 −− 1.20 −− 1.13
SD
CV
1 −−
−−
0.240
152.0
2 −−
−−
0.100
8.3
3 −−
−−
0.109
9.7
# Points −− 114 −− 36 −− 81
# Labs 2 1 2

Mean −− 0.000 −− −− −− 1.10
SD
CV
1 −−
−−
0.000
−−
2 −−
−−
−−
−−
3 −−
−−
0.089
8.1
# Points −− 193 −− −− −− 166
# Labs 1 1

Mean −− −− −− 0.652 −− 1.09
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.077
11.8
3 −−
−−
0.127
11.6
# Points −− −− −− 98 −− 214
# Labs 1 1

Mean −− 0.000 −− −− −− 0.971
SD
CV
1 −−
−−
0.000
−−
2 −−
−−
−−
−−
3 −−
−−
0.097
10.0
# Points −− 76 −− −− −− 72
# Labs 1 1

Mean −− 0.185 −− −− −− 1.34
SD
CV
1 −−
−−
0.194
105.0
2 −−
−−
−−
−−
3 −−
−−
0.350
26.2
# Points −− 70 −− −− −− 72
# Labs 1 1

Mean −− 0.291 −− 0.563 −− 1.33
SD
CV
1 −−
−−
0.140
48.0
2 −−
−−
0.384
68.1
3 −−
−−
0.471
35.4
# Points −− 107 −− 45 −− 146
# Labs 3 2 4

Mean −− 0.000 −− 0.610 −− 0.959
SD
CV
1 −−
−−
0.000
−−
2 −−
−−
0.072
11.9
3 −−
−−
0.181
18.9
# Points −− 145 −− 40 −− 272
# Labs 1 1 3

Mean −− 0.187 −− 0.779 −− 1.75
SD
CV
1 −−
−−
0.051
27.3
2 −−
−−
0.081
10.4
3 −−
−−
0.270
15.4
# Points −− 14 −− 12 −− 13
# Labs 1 1 1

Mean −− 0.000 −− 0.631 −− 1.04
SD
CV
1 −−
−−
0.000
−−
2 −−
−−
0.064
10.1
3 −−
−−
0.118
11.4
# Points −− 73 −− 337 −− 345
# Labs 1 1 1

Mean −− 0.145 −− −− −− 1.22
SD
CV
1 −−
−−
0.131
90.6
2 −−
−−
−−
−−
3 −−
−−
0.313
25.6
# Points −− 152 −− −− −− 39
# Labs 2 2

Mean −− 0.002 −− 0.715 −− 1.22
SD
CV
1 −−
−−
0.014
709.4
2 −−
−−
0.100
13.9
3 −−
−−
0.241
19.8
# Points −− 670 −− 512 −− 815
# Labs 2 1 3

Mean −− 0.285 −− −− −− −−
SD
CV
1 −−
−−
0.139
48.8
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 39 −− −− −− −−
# Labs 1

Mean −− 0.005 −− 0.659 −− 1.18
SD
CV
1 −−
−−
0.018
380.2
2 −−
−−
0.051
7.8
3 −−
−−
0.111
9.4
# Points −− 287 −− 216 −− 258
# Labs 2 1 2

Mean −− 0.000 −− 0.695 −− 1.21
SD
CV
1 −−
−−
0.000
−−
2 −−
−−
0.090
12.9
3 −−
−−
0.245
20.2
# Points −− 278 −− 650 −− 737
# Labs 2 2 3

Mean −− 0.000 −− 0.510 −− −−
SD
CV
1 −−
−−
0.000
−−
2 −−
−−
0.000
0.0
3 −−
−−
−−
−−
# Points −− 1 −− 1 −− −−
# Labs 1 1

Mean −− −− −− −− −− 1.06
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
0.116
10.9
# Points −− −− −− −− −− 160
# Labs 1

Mean −− 0.000 −− −− −− 1.09
SD
CV
1 −−
−−
0.000
−−
2 −−
−−
−−
−−
3 −−
−−
0.082
7.6
# Points −− 158 −− −− −− 153
# Labs 1 1

Mean −− 0.000 −− 0.924 −− 1.88
SD
CV
1 −−
−−
0.000
−−
2 −−
−−
0.134
14.6
3 −−
−−
0.311
16.6
# Points −− 131 −− 845 −− 837
# Labs 1 4 4

Mean −− 0.023 −− 0.480 −− 1.12
SD
CV
1 −−
−−
0.079
348.8
2 −−
−−
0.085
17.8
3 −−
−−
0.100
8.9
# Points −− 243 −− 237 −− 230
# Labs 2 1 1

Mean −− −− −− 0.648 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.062
9.5
3 −−
−−
−−
−−
# Points −− −− −− 66 −− −−
# Labs 1

Mean −− 0.000 −− 0.581 −− 1.02
SD
CV
1 −−
−−
0.000
−−
2 −−
−−
0.100
17.1
3 −−
−−
0.098
9.6
# Points −− 106 −− 46 −− 109
# Labs 2 1 2

Mean 0.000 0.000 0.675 0.650 1.04 1.04
SD
CV
1 0.000
−−
0.000
−−
2 0.048
7.0
0.052
8.0
3 0.121
11.6
0.131
12.6
# Points 62 262 31 117 66 278
# Labs 2 3 1 2 2 2

Mean −− −− −− 0.672 1.09 1.23
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.106
15.7
3 0.080
7.3
0.122
9.9
# Points −− −− −− 723 28 762
# Labs 2 1 1

Mean −− −− −− 0.627 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.056
8.9
3 −−
−−
−−
−−
# Points −− −− −− 25 −− −−
# Labs 1

Mean 0.352 0.011 1.04 0.525 2.48 1.06
SD
CV
1 0.068
19.2
0.062
575.8
2 0.060
5.8
0.097
18.5
3 0.207
8.3
0.266
25.1
# Points 4 132 3 130 4 125
# Labs 1 2 1 2 1 2

Mean −− 4.72 0.670 0.537 −− 12.23
SD
CV
1 −−
−−
6.35
134.6
2 0.014
2.1
0.070
12.9
3 −−
−−
21.36
174.7
# Points −− 64 2 31 −− 41
# Labs 2 1 1 2

Mean −− 0.000 −− 0.463 −− 0.994
SD
CV
1 −−
−−
0.000
−−
2 −−
−−
0.000
0.0
3 −−
−−
0.000
0.0
# Points −− 2 −− 1 −− 1
# Labs 1 1 1

Mean 0.030 0.030 0.643 0.643 −− −−
SD
CV
1 0.013
42.6
0.013
42.6
2 0.041
6.4
0.041
6.4
3 −−
−−
−−
−−
# Points 12 12 23 23 −− −−
# Labs 1 1 1 1

Mean −− 0.394 −− −− −− 2.34
SD
CV
1 −−
−−
0.077
19.6
2 −−
−−
−−
−−
3 −−
−−
0.164
7.0
# Points −− 94 −− −− −− 94
# Labs 1 1

Mean −− 0.376 −− −− −− 2.20
SD
CV
1 −−
−−
0.023
6.2
2 −−
−−
−−
−−
3 −−
−−
0.162
7.4
# Points −− 97 −− −− −− 100
# Labs 1 1

Mean −− 0.156 −− −− −− 1.78
SD
CV
1 −−
−−
0.138
88.4
2 −−
−−
−−
−−
3 −−
−−
0.484
27.2
# Points −− 146 −− −− −− 128
# Labs 1 1

Mean −− 0.000 −− −− −− 1.21
SD
CV
1 −−
−−
0.000
−−
2 −−
−−
−−
−−
3 −−
−−
0.113
9.3
# Points −− 172 −− −− −− 138
# Labs 1 1

Method Group • Calculated
Mean 0.023 0.131 0.681 0.708 1.11 1.37
SD
CV
1 0.079
349.1
1.01
774.3
2 0.095
14.0
0.177
24.9
3 0.306
27.5
2.01
146.3
# Points 78 3873 59 3810 98 5960
# Labs 4 40 4 28 4 44
Bilirubin, Direct/BC (DBIL) Diazotization mg/dL

Mean 0.287 0.310 1.35 1.48 2.61 2.74
SD
CV
1 0.033
11.5
0.030
9.7
2 0.073
5.4
0.091
6.1
3 0.100
3.8
0.106
3.9
# Points 1763 64036 1257 36534 914 61093
# Labs 63 225 48 141 35 176
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH Direct Bilirubin REF 8G63
Mean 0.239 0.269 1.15 1.20 −− −−
SD
CV
1 0.023
9.5
0.035
13.1
2
0.085
7.4
0.179
15.0
3 −−
−−
−−
−−
# Points 27 224 27 229 −− −−
# Labs 2 2 2 2
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c Bili D, REF 07P97

Mean 0.280 0.309 1.37 1.33 2.59 2.84
SD
CV
1 0.006
2.3
0.042
13.7
20.006
0.4
0.035
2.7
3 0.049
1.9
0.176
6.2
# Points 6 318 3 87 11 247
# Labs 1 3 1 2 1 2

Mean 0.249 0.253 1.36 1.39 2.74 2.81
SD
CV
1 0.006
2.3
0.008
3.0
2 0.032
2.3
0.033
2.4
3 0.031
1.1
0.053
1.9
# Points 18 411 19 452 18 454
# Labs 1 1 1 1 1 1
Abbott ARCHITECT/Alinity (c, i, ci models) • Reagent, Alternate Calibration − Shift DOWN

Mean 0.280 0.274 1.38 1.38 −− −−
SD
CV
1 0.020
7.1
0.023
8.3
2
0.070
5.1
0.060
4.4
3 −−
−−
−−
−−
# Points 28 191 28 173 −− −−
# Labs 1 1 1 1

Mean 0.272 0.282 1.30 1.38 2.51 2.52
SD
CV
1 0.030
11.0
0.029
10.3
2 0.113
8.7
0.088
6.4
3 0.124
4.9
0.123
4.9
# Points 2016 105K 1601 56169 1183 107K
# Labs 69 310 52 181 38 288

Mean −− 0.287 −− 1.42 −− 2.58
SD
CV
1 −−
−−
0.011
3.8
2 −−
−−
0.060
4.2
3 −−
−−
0.074
2.9
# Points −− 676 −− 982 −− 679
# Labs 6 8 6

Mean −− 0.279 −− −− −− 2.59
SD
CV
1 −−
−−
0.010
3.7
2 −−
−−
−−
−−
3 −−
−−
0.092
3.5
# Points −− 219 −− −− −− 219
# Labs 1 1
Beckman Coulter AU Series • Roche Direct Bilirubin (Doumas)

Mean −− 0.300 −− 1.37 −− 2.61
SD
CV
1 −−
−−
0.015
5.1
2
−−
−−
0.067
4.9
3 −−
−−
0.125
4.8
# Points −− 125 −− 125 −− 125
# Labs 1 1 1

Mean 0.192 0.212 −− 0.972 1.71 1.77
SD
CV
1 0.025
13.3
0.039
18.6
2 −−
−−
0.075
7.7
3 0.044
2.6
0.080
4.5
# Points 59 9738 −− 2028 63 9038
# Labs 2 35 8 2 32

Mean 0.260 0.286 1.27 1.32 2.92 2.67
SD
CV
1 0.025
9.5
0.033
11.5
2 0.090
7.1
0.142
10.7
3 0.309
10.6
0.207
7.8
# Points 30 502 28 398 5 43
# Labs 2 3 2 3 1 1
ERBA XL−640
Mean −− 0.223 −− 0.979 −− −−
SD
CV
1 −−
−−
0.020
9.1
2 −−
−−
0.072
7.4
3 −−
−−
−−
−−
# Points −− 50 −− 50 −− −−
# Labs 1 1
Fuji Dri−Chem Series • Fuji Dri−Chem DBIL−PII, REF 9903110

Mean −− 0.223 −− 1.42 −− −−
SD
CV
1 −−
−−
0.061
27.5
2 −−
−−
0.115
8.1
3 −−
−−
−−
−−
# Points −− 22 −− 22 −− −−
# Labs 2 2

Mean −− 0.223 −− 1.32 −− 2.27
SD
CV
1 −−
−−
0.044
19.7
2 −−
−−
0.176
13.3
3 −−
−−
0.099
4.4
# Points −− 317 −− 65 −− 262
# Labs 2 1 2

Mean −− 0.308 −− 1.47 −− 2.79
SD
CV
1 −−
−−
0.021
6.9
2 −−
−−
0.079
5.4
3 −−
−−
0.163
5.8
# Points −− 227 −− 212 −− 226
# Labs 2 1 2
ILab Series
Mean 0.128 0.156 0.953 1.07 −− −−
SD
CV
1 0.016
12.5
0.028
18.1
2 0.035
3.7
0.118
11.0
3 −−
−−
−−
−−
# Points 11 50 11 50 −− −−
# Labs 1 1 1 1
Mindray BS Series
Mean −− 0.276 −− 2.55 −− −−
SD
CV
1 −−
−−
0.005
1.8
2 −−
−−
0.030
1.2
3 −−
−−
−−
−−
# Points −− 232 −− 235 −− −−
# Labs 1 1
Mindray CL Series
Mean −− −− −− 1.30 −− 2.53
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.024
1.8
3 −−
−−
0.028
1.1
# Points −− −− −− 89 −− 90
# Labs 1 1
RANDOX RX daytona
Mean 0.156 0.171 0.889 0.597 2.98 1.62
SD
CV
1 0.168
107.8
0.172
100.5
2 0.694
78.1
0.674
113.0
3 0.000
0.0
1.92
117.9
# Points 44 414 28 235 1 2
# Labs 2 2 2 2 1 2

RANDOX RX imola
Mean 0.303 0.294 1.28 1.28 −− −−
SD
CV
1 0.010
3.2
0.025
8.5
2 0.039
3.0
0.052
4.1
3 −−
−−
−−
−−
# Points 26 226 24 195 −− −−
# Labs 1 1 1 1

Mean 0.299 0.328 1.18 1.59 2.13 3.11
SD
CV
1 0.017
5.6
0.038
11.6
2 0.118
10.0
0.172
10.8
3 0.071
3.4
0.324
10.4
# Points 32 6584 173 8671 115 10955
# Labs 1 18 3 24 1 30
Roche cobas 6000/8000/c 311 • Roche BILD2 (Doumas)

Mean 0.314 0.320 1.55 1.55 3.16 3.06
SD
CV
1 0.014
4.5
0.030
9.3
2 0.035
2.2
0.155
10.0
3 0.040
1.3
0.273
8.9
# Points 207 9267 93 6041 112 7273
# Labs 4 30 2 26 2 20
Roche cobas 6000/8000/c 311 • Roche BILD2 (International)

Mean −− 0.322 −− 1.61 −− 3.08
SD
CV
1 −−
−−
0.029
9.1
2 −−
−−
0.054
3.4
3 −−
−−
0.104
3.4
# Points −− 239 −− 415 −− 174
# Labs 2 2 2
Roche cobas 6000/8000/c 311 • Roche Direct Bilirubin (Doumas)

Mean 0.193 0.199 0.954 0.959 1.86 1.92
SD
CV
1 0.013
6.6
0.011
5.4
2
0.056
5.8
0.059
6.2
3 0.097
5.2
0.083
4.3
# Points 1184 29716 174 6999 1145 28579
# Labs 26 78 5 16 25 78
Roche cobas 6000/8000/c 311 • Roche Direct Bilirubin (Jendrassik−Grof)

Mean 0.321 0.323 −− 1.61 3.11 3.15
SD
CV
1 0.013
4.0
0.014
4.4
2 −−
−−
0.063
3.9
3 0.046
1.5
0.090
2.8
# Points 195 9580 −− 6682 195 12208
# Labs 4 18 19 4 27

Mean −− 0.203 −− 0.984 −− 1.96
SD
CV
1 −−
−−
0.011
5.4
2 −−
−−
0.040
4.0
3 −−
−−
0.053
2.7
# Points −− 488 −− 485 −− 489
# Labs 2 2 2
Roche cobas c 303/503 • Roche BILD2 (Doumas)

Mean 0.333 0.306 1.64 1.69 3.30 3.05
SD
CV
1 0.009
2.6
0.049
16.0
2 0.015
0.9
0.043
2.5
3 0.028
0.8
0.592
19.4
# Points 19 256 20 194 20 257
# Labs 1 2 1 1 1 2
Roche cobas c 303/503 • Roche Direct Bilirubin (Doumas)

Mean 0.218 0.215 −− 0.995 1.98 2.04
SD
CV
1 0.036
16.4
0.035
16.1
2 −−
−−
0.073
7.3
3 0.091
4.6
0.088
4.3
# Points 250 7576 −− 1938 181 7089
# Labs 8 25 5 6 21
Roche cobas c 303/503 • Roche Direct Bilirubin (Jendrassik−Grof)

Mean 0.338 0.349 1.66 1.71 3.29 3.34
SD
CV
1 0.012
3.6
0.015
4.3
2
0.037
2.2
0.056
3.3
3 0.078
2.4
0.093
2.8
# Points 142 3644 62 2601 138 3606
# Labs 5 9 2 6 5 9

Roche cobas c 303/503 • Roche c303/503 BILT3/BILD2 (Doumas)
Mean −− 0.205 −− −− −− 2.03
SD
CV
1 −−
−−
0.007
3.4
−−
−−
2 −−
−−
3 −−
−−
0.014
0.7
# Points −− 2 −− −− −− 2
# Labs 1 1
Roche cobas c 303/503 • Roche c303/503 BILT3/BILD2 (Jendrassik)

Mean 0.346 0.350 1.69 1.73 3.40 3.37
SD
CV
1 0.011
3.2
0.019
5.4
2
0.047
2.8
0.059
3.4
3 0.057
1.7
0.136
4.0
# Points 26 970 27 1282 27 894
# Labs 1 3 1 2 1 3

Mean 0.314 0.323 1.52 1.59 3.04 3.10
SD
CV
1 0.015
4.8
0.016
5.0
2 0.059
3.9
0.062
3.9
3 0.096
3.1
0.112
3.6
# Points 64 713 64 1001 64 995
# Labs 2 2 2 3 2 3

Mean −− 0.325 −− −− −− 3.23
SD
CV
1 −−
−−
0.012
3.6
2 −−
−−
−−
−−
3 −−
−−
0.076
2.4
# Points −− 26 −− −− −− 25
# Labs 1 1

Mean −− 0.192 −− 1.01 −− 1.96
SD
CV
1 −−
−−
0.011
5.9
2 −−
−−
0.020
2.0
3 −−
−−
0.060
3.1
# Points −− 600 −− 219 −− 601
# Labs 4 1 4
Roche cobas Integra / c 111 • Roche Direct Bilirubin (Doumas)

Mean −− 0.200 −− −− −− 1.88
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
−−
−−
3 −−
−−
0.103
5.5
# Points −− 378 −− −− −− 379
# Labs 3 3

Mean 0.281 0.290 1.32 1.44 2.70 2.99
SD
CV
1 0.015
5.2
0.030
10.4
2 0.060
4.6
0.085
5.9
3 0.056
2.1
0.194
6.5
# Points 31 940 31 936 31 844
# Labs 1 4 1 4 1 3
Mean −− 0.286 −− 1.32 −− 2.57
SD
CV
1 −−
−−
0.019
6.5
2 −−
−−
0.061
4.7
3 −−
−−
0.127
5.0
# Points −− 266 −− 616 −− 617
# Labs 1 4 2
Roche Hitachi/MODULAR • Wako

Mean −− 0.225 −− −− −− 2.38
SD
CV
1 −−
−−
0.045
19.9
2 −−
−−
−−
−−
3 −−
−−
0.093
3.9
# Points −− 278 −− −− −− 278
# Labs 1 1

Mean −− −− −− 1.36 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.062
4.6
3 −−
−−
−−
−−
# Points −− −− −− 25 −− −−
# Labs 1

Mean −− −− −− 1.43 −− 2.77
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.035
2.5
3 −−
−−
0.043
1.6
# Points −− −− −− 52 −− 51
# Labs 1 1

Mean −− 0.284 −− 1.13 −− 2.65
SD
CV
1 −−
−−
0.025
8.9
2 −−
−−
0.044
3.9
3 −−
−−
0.223
8.4
# Points −− 1330 −− 173 −− 1313
# Labs 4 1 4
Siemens Atellica CH Analyzer • Sekisui Diagnostics SEKURE

Mean −− 0.233 −− 1.13 −− 2.11
SD
CV
1 −−
−−
0.016
6.9
2 −−
−−
0.070
6.2
3 −−
−−
0.123
5.8
# Points −− 179 −− 179 −− 178
# Labs 1 1 1

Mean 0.183 0.193 0.854 0.925 1.82 1.88
SD
CV
1 0.028
15.5
0.026
13.2
2 0.078
9.1
0.080
8.7
3 0.086
4.7
0.057
3.1
# Points 1473 90165 407 17196 1318 297K
# Labs 51 244 13 62 46 212

Mean 0.198 0.206 0.933 1.00 1.91 1.94
SD
CV
1 0.025
12.7
0.028
13.4
2 0.069
7.4
0.074
7.4
3 0.087
4.5
0.081
4.2
# Points 3234 234K 988 74056 2695 208K
# Labs 91 466 32 140 79 441

Mean −− −− 1.39 1.38 −− −−
SD
CV
1 −−
−−
−−
−−
2 0.078
5.7
0.071
5.2
3 −−
−−
−−
−−
# Points −− −− 20 28 −− −−
# Labs 1 1

Mean −− 0.211 −− 0.904 −− 1.63
SD
CV
1 −−
−−
0.022
10.3
2 −−
−−
0.034
3.8
3 −−
−−
0.064
3.9
# Points −− 108 −− 108 −− 108
# Labs 1 1 1
Mean −− 0.286 −− 1.33 −− 2.46
SD
CV
1 −−
−−
0.013
4.4
2 −−
−−
0.050
3.8
3 −−
−−
0.090
3.7
# Points −− 444 −− 449 −− 468
# Labs 3 3 3

Mean −− −− −− 0.656 −− 1.11
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.100
15.2
3 −−
−−
0.078
7.0
# Points −− −− −− 248 −− 239
# Labs 1 1

Mean −− −− −− 0.750 −− 1.16
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.105
13.9
3 −−
−−
0.128
11.1
# Points −− −− −− 32 −− 114
# Labs 2 2

Mean −− 0.353 −− 1.36 −− −−
SD
CV
1 −−
−−
0.390
110.3
2 −−
−−
0.149
10.9
3 −−
−−
−−
−−
# Points −− 159 −− 159 −− −−
# Labs 1 1
Method Group • Diazotization

Mean 0.233 0.236 1.20 1.24 2.15 2.12
SD
CV
1 0.055
23.7
0.055
23.3
2 0.233
19.3
0.266
21.4
3 0.419
19.5
0.387
18.2
# Points 10885 581K 5085 229K 8236 763K
# Labs 340 1524 174 691 252 1393
Bilirubin, Direct/BC (DBIL) Direct measure mg/dL

Mean 0.284 0.268 1.61 1.63 −− −−
SD
CV
1 0.021
7.2
0.030
11.2
2 0.012
0.7
0.085
5.2
3 −−
−−
−−
−−
# Points 5 110 4 96 −− −−
# Labs 1 2 1 2
Hitachi Chemistry Series • Mitsubishi Kagaku Iatron, Inc.

Mean −− 0.219 −− −− −− −−
SD
CV
1 −−
−−
0.007
3.1
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 64 −− −− −− −−
# Labs 1

Mean −− −− −− 1.82 −− 3.02
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.097
5.4
3 −−
−−
0.142
4.7
# Points −− −− −− 7 −− 6
# Labs 1 1
Roche cobas 6000/8000/c 311 • Roche Direct Bilirubin (Doumas)

Mean −− 0.199 −− −− −− 1.90
SD
CV
1 −−
−−
0.030
14.9
−−
−−
2 −−
−−
3 −−
−−
0.194
10.2
# Points −− 122 −− −− −− 127
# Labs 2 2

Mean −− 0.187 −− −− −− 2.02
SD
CV
1 −−
−−
0.020
10.8
2 −−
−−
−−
−−
3 −−
−−
0.077
3.8
# Points −− 18 −− −− −− 17
# Labs 1 1
Roche cobas c 303/503 • Roche Direct Bilirubin (Jendrassik−Grof)

Mean −− 0.192 −− −− −− 1.99
SD
CV
1 −−
−−
0.017
9.0
2
−−
−−
−−
−−
3 −−
−−
0.076
3.8
# Points −− 371 −− −− −− 379
# Labs 2 2

Mean −− 0.000 −− −− −− 0.971
SD
CV
1 −−
−−
0.000
−−
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− 1 −− −− −− 1
# Labs 1 1

Mean −− 0.152 −− 0.699 −− −−
SD
CV
1 −−
−−
0.101
66.7
2 −−
−−
0.101
14.5
3 −−
−−
−−
−−
# Points −− 5 −− 32 −− −−
# Labs 1 1

Mean −− 0.000 −− 0.608 −− 1.09
SD
CV
1 −−
−−
0.000
−−
2 −−
−−
0.074
12.2
3 −−
−−
0.080
7.3
# Points −− 761 −− 814 −− 799
# Labs 2 2 2

Mean −− −− −− 0.688 −− 1.15
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.099
14.5
3 −−
−−
0.082
7.1
# Points −− −− −− 98 −− 100
# Labs 3 3

Mean −− 0.000 −− −− −− 0.992
SD
CV
1 −−
−−
0.000
−−
2 −−
−−
−−
−−
3 −−
−−
0.158
15.9
# Points −− 211 −− −− −− 174
# Labs 3 3

Mean −− 0.034 −− −− −− 1.52
SD
CV
1 −−
−−
0.049
144.5
2 −−
−−
−−
−−
3 −−
−−
0.130
8.6
# Points −− 69 −− −− −− 70
# Labs 1 1

Mean −− 0.002 −− 0.521 −− 1.02
SD
CV
1 −−
−−
0.009
529.8
2 −−
−−
0.134
25.6
3 −−
−−
0.144
14.1
# Points −− 57 −− 421 −− 420
# Labs 3 3 3

Mean −− −− −− 0.651 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.091
13.9
3 −−
−−
−−
−−
# Points −− −− −− 226 −− −−
# Labs 2

Mean −− −− −− 0.505 −− 1.05
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.158
31.2
3 −−
−−
0.139
13.2
# Points −− −− −− 197 −− 255
# Labs 1 1

Mean −− 0.016 −− −− −− 1.11
SD
CV
1 −−
−−
0.067
430.0
2 −−
−−
−−
−−
3 −−
−−
0.071
6.3
# Points −− 38 −− −− −− 40
# Labs 1 1

Mean −− −− −− 0.633 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.100
15.8
3 −−
−−
−−
−−
# Points −− −− −− 139 −− −−
# Labs 2

Mean −− 0.000 −− 0.596 −− 1.12
SD
CV
1 −−
−−
0.000
−−
2 −−
−−
0.135
22.6
3 −−
−−
0.138
12.4
# Points −− 1096 −− 1275 −− 1484
# Labs 5 5 5

Mean −− 0.249 −− 0.733 −− −−
SD
CV
1 −−
−−
0.133
53.2
2 −−
−−
0.178
24.3
3 −−
−−
−−
−−
# Points −− 68 −− 296 −− −−
# Labs 2 4

Mean −− 0.070 −− 0.553 −− 1.07
SD
CV
1 −−
−−
0.144
206.0
2 −−
−−
0.190
34.4
3 −−
−−
0.124
11.6
# Points −− 170 −− 520 −− 588
# Labs 5 8 6

Mean −− 0.331 −− 0.657 −− −−
SD
CV
1 −−
−−
0.123
37.2
2 −−
−−
0.153
23.3
3 −−
−−
−−
−−
# Points −− 59 −− 96 −− −−
# Labs 2 2

Mean −− 0.000 −− 0.588 −− 1.25
SD
CV
1 −−
−−
0.000
−−
2 −−
−−
0.069
11.8
3 −−
−−
0.000
0.0
# Points −− 1 −− 201 −− 1
# Labs 1 2 1

Mean 0.882 0.496 0.694 0.787 −− −−
SD
CV
1 2.25
254.5
1.02
205.8
2 0.146
21.1
0.274
34.8
3 −−
−−
−−
−−
# Points 12 57 31 152 −− −−
# Labs 2 2 2 2

Mean 0.536 0.535 1.04 0.614 −− −−
SD
CV
1 0.033
6.1
0.032
6.0
2 0.062
5.9
0.220
35.7
3 −−
−−
−−
−−
# Points 24 25 24 130 −− −−
# Labs 1 1 1 3

Mean −− 0.083 0.378 0.461 1.23 1.23
SD
CV
1 −−
−−
0.000
0.0
2 0.106
28.0
0.139
30.1
3 0.108
8.8
0.109
8.9
# Points −− 1 12 22 59 78
# Labs 1 1 2 3 3
Method Group • Direct measure

Mean 0.607 0.072 0.809 0.633 1.23 1.21
SD
CV
1 1.19
196.9
0.183
256.1
2 0.324
40.1
0.217
34.3
3 0.108
8.8
0.327
27.1
# Points 41 3304 71 4525 59 4284
# Labs 4 39 5 44 3 35
Bilirubin, Direct/BC (DBIL) Enzymatic mg/dL

Mean −− 0.325 −− 1.53 −− 2.79
SD
CV
1 −−
−−
0.009
2.7
2 −−
−−
0.022
1.4
3 −−
−−
0.029
1.0
# Points −− 64 −− 58 −− 56
# Labs 2 2 2
Beckman Coulter AU Series • Nipro

Mean −− 0.246 −− 1.41 −− 3.37
SD
CV
1 −−
−−
0.010
4.2
2 −−
−−
0.062
4.4
3 −−
−−
0.152
4.5
# Points −− 2049 −− 3015 −− 2861
# Labs 2 5 5
Bilirubin, Direct/BC (DBIL) Enzymatic mg/dL

Mean −− 0.248 −− 1.41 −− 3.36
SD
CV
1 −−
−−
0.017
6.8
2 −−
−−
0.064
4.5
3 −−
−−
0.171
5.1
# Points −− 2113 −− 3073 −− 2917
# Labs 4 7 7
Bilirubin, Direct/BC (DBIL) Oxidation by Nitrite mg/dL

Mean −− −− −− 1.29 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.038
3.0
3 −−
−−
−−
−−
# Points −− −− −− 177 −− −−
# Labs 1
Method Group • Oxidation by Nitrite

Mean −− −− −− 1.29 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.038
3.0
3 −−
−−
−−
−−
# Points −− −− −− 177 −− −−
# Labs 1
Bilirubin, Direct/BC (DBIL) Spectrophotometric mg/dL

Mean 0.000 0.017 −− 0.564 0.880 1.05
SD
CV
1 0.000
−−
0.107
631.8
2 −−
−−
0.150
26.7
3 0.060
6.8
0.145
13.9
# Points 9 617 −− 786 15 1118
# Labs 1 11 9 1 6

Mean −− 0.000 −− 0.609 −− 1.12
SD
CV
1 −−
−−
0.000
−−
2 −−
−−
0.109
18.0
3 −−
−−
0.089
7.9
# Points −− 142 −− 501 −− 622
# Labs 2 4 4

Mean −− 0.000 −− 0.587 −− 1.14
SD
CV
1 −−
−−
0.000
−−
2 −−
−−
0.102
17.4
3 −−
−−
0.132
11.5
# Points −− 317 −− 248 −− 380
# Labs 4 3 5

Mean −− −− −− 0.511 −− 1.00
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.077
15.1
3 −−
−−
0.088
8.8
# Points −− −− −− 103 −− 99
# Labs 4 4

Mean −− 0.000 −− 0.618 −− 1.19
SD
CV
1 −− 0.001
−− 1699.5
2 −−
−−
0.105
17.0
3 −−
−−
0.193
16.2
# Points −− 302 −− 395 −− 718
# Labs 4 4 5

Mean −− 0.262 −− 0.718 −− 1.38
SD
CV
1 −−
−−
0.168
64.1
2 −−
−−
0.153
21.3
3 −−
−−
0.431
31.3
# Points −− 316 −− 1052 −− 630
# Labs 4 11 6

Mean −− 0.513 −− 0.682 −− 1.13
SD
CV
1 −−
−−
0.277
54.1
2 −−
−−
0.106
15.5
3 −−
−−
0.154
13.6
# Points −− 61 −− 1453 −− 1342
# Labs 3 9 9

Mean −− 0.055 −− 0.717 −− 1.21
SD
CV
1 −−
−−
0.134
243.2
2 −−
−−
0.110
15.3
3 −−
−−
0.254
21.0
# Points −− 760 −− 1485 −− 1089
# Labs 13 17 13

Mean −− 0.082 −− 0.684 −− 1.15
SD
CV
1 −−
−−
0.121
147.0
2 −−
−−
0.128
18.8
3 −−
−−
0.387
33.5
# Points −− 682 −− 1707 −− 1447
# Labs 13 23 19

Mean −− 0.002 −− 0.748 −− 1.13
SD
CV
1 −− 0.029
−− 1369.2
2 −−
−−
0.088
11.8
3 −−
−−
0.141
12.5
# Points −− 1753 −− 2178 −− 2562
# Labs 18 16 18

Mean −− 0.000 −− 0.780 −− 1.17
SD
CV
1 −−
−−
0.000
−−
2 −−
−−
0.054
6.9
3 −−
−−
0.153
13.0
# Points −− 192 −− 379 −− 95
# Labs 3 7 4

Mean −− 0.005 −− 0.715 −− 1.11
SD
CV
1 −−
−−
0.023
486.6
2 −−
−−
0.094
13.1
3 −−
−−
0.119
10.8
# Points −− 1873 −− 2364 −− 5051
# Labs 24 21 28

Mean −− 0.000 −− 0.678 −− 1.19
SD
CV
1 −−
−−
0.001
−−
2 −−
−−
0.100
14.8
3 −−
−−
0.138
11.6
# Points −− 658 −− 1985 −− 2224
# Labs 14 20 23

Mean −− 0.000 −− 0.658 −− 1.05
SD
CV
1 −− 0.000
−− 1536.2
2 −−
−−
0.102
15.5
3 −−
−−
0.133
12.7
# Points −− 710 −− 431 −− 770
# Labs 10 6 10

Mean −− 0.003 −− 0.714 −− 1.35
SD
CV
1 −−
−−
0.018
514.9
2 −−
−−
0.112
15.7
3 −−
−−
0.112
8.3
# Points −− 1562 −− 997 −− 1541
# Labs 10 8 11

Mean −− 0.008 −− 0.694 −− 1.20
SD
CV
1 −−
−−
0.028
364.7
2 −−
−−
0.104
15.0
3 −−
−−
0.139
11.6
# Points −− 966 −− 2826 −− 1831
# Labs 14 26 16

Mean −− 0.005 −− 0.666 −− 1.16
SD
CV
1 −−
−−
0.018
363.2
2 −−
−−
0.140
21.0
3 −−
−−
0.118
10.2
# Points −− 960 −− 2021 −− 1623
# Labs 10 13 14

Mean −− 0.000 −− 0.659 −− 1.18
SD
CV
1 −− 0.005
−− 1908.0
2 −−
−−
0.108
16.5
3 −−
−−
0.129
10.9
# Points −− 1207 −− 1890 −− 2485
# Labs 12 15 17

Mean −− 0.006 −− 0.645 −− 1.09
SD
CV
1 −−
−−
0.023
403.2
2 −−
−−
0.081
12.5
3 −−
−−
0.105
9.7
# Points −− 850 −− 1551 −− 1866
# Labs 9 16 16

Mean −− 0.004 −− 0.681 −− 1.17
SD
CV
1 −−
−−
0.019
480.1
2 −−
−−
0.084
12.3
3 −−
−−
0.113
9.7
# Points −− 71 −− 825 −− 421
# Labs 2 8 4

Mean −− 0.007 −− 0.639 −− 1.14
SD
CV
1 −−
−−
0.066
982.7
2 −−
−−
0.119
18.7
3 −−
−−
0.119
10.5
# Points −− 791 −− 1776 −− 1510
# Labs 12 13 10

Mean 0.000 23.53 −− 0.696 −− 1.21
SD
CV
1 0.000
−−
28.55
121.3
2 −−
−−
0.072
10.4
3 −−
−−
0.109
9.0
# Points 15 222 −− 409 −− 440
# Labs 2 5 9 7

Mean −− 0.001 0.182 0.465 0.900 1.07
SD
CV
1 −− 0.024
−− 2053.9
2 0.097
53.3
0.142
30.4
3 0.067
7.4
0.141
13.1
# Points −− 834 93 2756 13 2044
# Labs 11 3 21 1 18

Mean −− 0.000 −− 0.592 −− 1.13
SD
CV
1 −−
−−
0.000
−−
2 −−
−−
0.108
18.3
3 −−
−−
0.100
8.9
# Points −− 507 −− 1169 −− 752
# Labs 8 14 10

Mean 0.000 0.000 −− 0.612 0.918 1.04
SD
CV
1 0.000
−−
0.000
−−
2 −−
−−
0.073
12.0
3 0.054
5.9
0.139
13.4
# Points 62 362 −− 243 60 572
# Labs 2 5 4 2 7

Mean 0.000 0.001 0.479 0.520 1.05 1.03
SD
CV
1 0.000 0.019
−− 2204.9
2 0.147
30.7
0.123
23.7
3 0.125
11.9
0.123
11.9
# Points 145 970 118 1113 147 1209
# Labs 5 14 5 14 5 13

Mean 0.000 0.000 0.504 0.572 0.974 1.01
SD
CV
1 0.000
−−
0.000
−−
2 0.153
30.4
0.132
23.1
3 0.043
4.4
0.087
8.6
# Points 21 42 73 350 32 225
# Labs 1 2 3 8 1 3

Mean 0.100 0.100 0.800 0.800 1.10 0.914
SD
CV
1 0.100
100.0
0.100
100.0
2 0.100
12.5
0.100
12.5
3 0.100
9.1
0.125
13.7
# Points 14 14 13 13 13 70
# Labs 1 1 1 1 1 2

Mean 0.002 0.005 0.641 0.627 1.09 1.02
SD
CV
1 0.009
515.7
0.021
401.5
2 0.068
10.6
0.076
12.1
3 0.111
10.2
0.146
14.4
# Points 114 610 146 609 145 887
# Labs 3 8 4 5 4 8

Mean 0.000 0.038 0.700 0.604 1.10 1.05
SD
CV
1 0.000
−−
0.090
238.4
2 0.100
14.3
0.110
18.2
3 0.100
9.1
0.166
15.7
# Points 10 191 11 417 11 506
# Labs 1 5 1 7 1 7

Mean −− −− −− −− −− 0.829
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
0.091
11.0
# Points −− −− −− −− −− 45
# Labs 2

Mean 0.000 0.000 0.524 0.532 1.09 1.06
SD
CV
1 0.000
−−
0.000
−−
2 0.154
29.4
0.135
25.4
3 0.075
6.9
0.093
8.8
# Points 68 117 81 132 50 99
# Labs 5 5 8 8 5 5

Mean 0.000 0.000 0.402 0.402 1.09 1.17
SD
CV
1 0.000
−−
0.000
−−
2 0.070
17.4
0.070
17.4
3 0.119
10.9
0.100
8.5
# Points 54 151 24 24 51 176
# Labs 2 4 1 1 3 3

Mean 0.000 0.053 −− 0.477 1.37 0.921
SD
CV
1 0.000
−−
0.047
87.9
2 −−
−−
0.040
8.3
3 0.000
0.0
0.105
11.4
# Points 10 47 −− 217 1 305
# Labs 2 3 1 1 3

Mean −− −− 0.732 0.709 1.27 1.26
SD
CV
1 −−
−−
−−
−−
2 0.109
14.9
0.108
15.3
3 0.097
7.7
0.092
7.3
# Points −− −− 66 87 67 89
# Labs 2 2 2 2

Mean −− 0.006 −− 0.670 −− 1.02
SD
CV
1 −−
−−
0.014
233.6
2 −−
−−
0.028
4.1
3 −−
−−
0.146
14.3
# Points −− 73 −− 54 −− 121
# Labs 2 1 2

Mean −− −− −− 0.377 −− 0.843
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.028
7.4
3 −−
−−
0.045
5.3
# Points −− −− −− 125 −− 125
# Labs 1 1

Mean −− 0.000 −− 0.656 −− 1.11
SD
CV
1 −−
−−
0.000
−−
2 −−
−−
0.063
9.6
3 −−
−−
0.083
7.5
# Points −− 121 −− 120 −− 123
# Labs 1 1 1

Mean −− −− −− 0.348 −− 0.803
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.041
11.8
3 −−
−−
0.072
8.9
# Points −− −− −− 36 −− 37
# Labs 1 1

Mean −− 0.000 −− 0.448 −− 0.913
SD
CV
1 −−
−−
0.000
−−
2 −−
−−
0.113
25.3
3 −−
−−
0.104
11.4
# Points −− 36 −− 261 −− 260
# Labs 1 2 2

Mean −− −− −− 0.576 −− 1.11
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.083
14.3
3 −−
−−
0.113
10.2
# Points −− −− −− 163 −− 167
# Labs 1 1

Mean −− 0.000 −− 0.513 −− 1.14
SD
CV
1 −−
−−
0.000
−−
2 −−
−−
0.065
12.7
3 −−
−−
0.097
8.6
# Points −− 101 −− 129 −− 128
# Labs 1 2 2

Mean −− −− −− 0.541 −− 1.15
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.039
7.3
3 −−
−−
0.070
6.1
# Points −− −− −− 86 −− 77
# Labs 1 1

Mean −− 0.000 −− 0.519 −− 1.18
SD
CV
1 −−
−−
0.000
−−
2 −−
−−
0.056
10.7
3 −−
−−
0.097
8.2
# Points −− 168 −− 258 −− 275
# Labs 1 2 2

Mean −− 0.000 −− 0.732 −− 1.13
SD
CV
1 −−
−−
0.000
−−
2 −−
−−
0.076
10.3
3 −−
−−
0.108
9.5
# Points −− 410 −− 566 −− 493
# Labs 5 5 5

Mean −− 0.380 −− −− −− 2.53
SD
CV
1 −−
−−
0.036
9.6
2 −−
−−
−−
−−
3 −−
−−
0.196
7.8
# Points −− 141 −− −− −− 130
# Labs 2 2

Method Group • Spectrophotometric
Mean 0.014 0.280 0.537 0.649 1.07 1.14
SD
CV
1 0.058 3.89
419.0 1390.0
2 0.231
43.1
0.138
21.3
3 0.140
13.1
0.198
17.4
# Points 544 19884 647 36101 605 38593
# Labs 26 281 29 366 27 354
Bilirubin, Direct/BC (DBIL) Vanadate Oxidation mg/dL

Mean 0.291 0.310 1.23 1.47 2.56 2.81
SD
CV
1 0.014
4.8
0.024
7.7
2 0.034
2.8
0.095
6.4
3 0.076
3.0
0.120
4.3
# Points 35 2087 36 2304 36 2298
# Labs 5 5 5 7 5 7

Mean 0.278 0.283 1.29 1.30 2.54 2.55
SD
CV
1 0.011
3.9
0.014
5.1
2 0.042
3.2
0.047
3.6
3 0.029
1.2
0.058
2.3
# Points 147 2494 147 2296 147 2492
# Labs 3 4 3 4 3 4

Mean −− −− −− 1.38 −− 2.83
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.065
4.7
3 −−
−−
0.106
3.7
# Points −− −− −− 576 −− 574
# Labs 2 2

Mean −− 0.299 −− 1.39 −− 2.82
SD
CV
1 −−
−−
0.009
3.0
2 −−
−−
0.123
8.8
3 −−
−−
0.245
8.7
# Points −− 1354 −− 1812 −− 1870
# Labs 2 4 4

Mean −− 0.285 −− 1.36 −− 2.75
SD
CV
1 −−
−−
0.024
8.4
2 −−
−−
0.079
5.8
3 −−
−−
0.157
5.7
# Points −− 218 −− 218 −− 217
# Labs 1 1 1

Mean 0.260 0.279 1.27 1.30 2.56 2.54
SD
CV
1 0.013
4.8
0.019
6.8
2 0.048
3.8
0.067
5.2
3 0.083
3.2
0.103
4.1
# Points 62 644 62 689 62 690
# Labs 2 2 2 2 2 2

Mean −− 0.284 −− 1.22 −− 2.63
SD
CV
1 −−
−−
0.047
16.6
2 −−
−−
0.045
3.7
3 −−
−−
0.291
11.1
# Points −− 1835 −− 742 −− 2260
# Labs 4 2 6

Mean −− −− 1.36 1.36 2.62 2.70
SD
CV
1 −−
−−
−−
−−
2 0.032
2.3
0.054
4.0
3 0.059
2.3
0.096
3.5
# Points −− −− 5 388 4 387
# Labs 1 1 1 1

Mean −− −− −− 1.39 −− 2.85
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.039
2.8
3 −−
−−
0.060
2.1
# Points −− −− −− 169 −− 169
# Labs 1 1

Dirui CS Series
Mean −− 0.266 −− 1.34 −− 2.74
SD
CV
1 −−
−−
0.048
18.2
2 −−
−−
0.105
7.8
3 −−
−−
0.141
5.1
# Points −− 700 −− 691 −− 697
# Labs 2 2 2

Mean −− −− 1.38 1.37 2.66 2.72
SD
CV
1 −−
−−
−−
−−
2 0.039
2.9
0.108
7.9
3 0.056
2.1
0.229
8.4
# Points −− −− 11 107 9 105
# Labs 2 2 2 2

Mean −− 0.256 −− 1.24 −− 2.38
SD
CV
1 −−
−−
0.025
9.7
2 −−
−−
0.067
5.4
3 −−
−−
0.159
6.7
# Points −− 4244 −− 2882 −− 4260
# Labs 11 7 11

Mean −− −− −− 1.38 −− 2.82
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.040
2.9
3 −−
−−
0.114
4.0
# Points −− −− −− 104 −− 104
# Labs 1 1

Mean −− 0.243 −− −− −− 2.83
SD
CV
1 −−
−−
0.012
4.9
2 −−
−−
−−
−−
3 −−
−−
0.104
3.7
# Points −− 91 −− −− −− 92
# Labs 1 1
Hitachi Chemistry Series • Wako

Mean −− 0.258 −− −− −− 2.46
SD
CV
1 −−
−−
0.019
7.3
2 −−
−−
−−
−−
3 −−
−−
0.085
3.4
# Points −− 414 −− −− −− 411
# Labs 2 2
Mindray BS Series
Mean 0.253 0.268 1.19 1.34 2.43 2.59
SD
CV
1 0.016
6.5
0.017
6.2
2 0.059
5.0
0.055
4.1
3 0.109
4.5
0.095
3.7
# Points 21 243 21 409 21 396
# Labs 1 2 1 2 1 2

Mean −− −− −− 1.43 −− 2.78
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.036
2.5
3 −−
−−
0.076
2.7
# Points −− −− −− 281 −− 283
# Labs 2 2

Mean 0.296 0.300 1.34 1.38 2.85 2.85
SD
CV
1 0.019
6.3
0.018
6.0
2 0.160
11.9
0.139
10.1
3 0.100
3.5
0.104
3.6
# Points 62 184 62 184 62 184
# Labs 2 2 2 2 2 2

Mean −− −− −− 1.36 −− 2.79
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.041
3.0
3 −−
−−
0.082
3.0
# Points −− −− −− 321 −− 320
# Labs 1 1

Mean −− 0.301 −− 1.42 −− 2.83
SD
CV
1 −−
−−
0.017
5.6
2 −−
−−
0.046
3.2
3 −−
−−
0.052
1.8
# Points −− 630 −− 631 −− 631
# Labs 2 2 2

Mean 0.264 0.280 1.20 1.32 2.57 2.64
SD
CV
1 0.026
9.8
0.021
7.3
2 0.089
7.4
0.090
6.8
3 0.074
2.9
0.116
4.4
# Points 125 13798 91 10706 92 13701
# Labs 4 34 4 29 4 32
Siemens ADVIA Chemistry Systems • Alternate Calibration

Mean −− 0.285 −− 1.36 −− 2.67
SD
CV
1 −−
−−
0.012
4.1
2 −−
−−
0.043
3.2
3 −−
−−
0.058
2.2
# Points −− 417 −− 244 −− 417
# Labs 2 2 2

Mean 0.266 0.295 1.28 1.37 2.83 2.81
SD
CV
1 0.031
11.6
0.025
8.4
2 0.096
7.5
0.096
7.0
3 0.141
5.0
0.144
5.1
# Points 517 30277 425 15933 229 23113
# Labs 17 96 15 66 10 76
Siemens Atellica CH Analyzer • Siemens Atellica CH DBil_2, REF 11097532

Mean −− 0.225 −− 1.13 −− −−
SD
CV
1 −−
−−
0.018
8.1
−−
−−
2 0.050
4.4
3 −−
−−
−−
−−
# Points −− 4 −− 4 −− −−
# Labs 1 1
Toshiba−TBA
Mean −− −− −− −− −− 2.86
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
0.113
3.9
# Points −− −− −− −− −− 84
# Labs 1
Toshiba−TBA • Wako
Mean 0.320 0.302 −− −− 2.85 2.82
SD
CV
1 0.010
3.1
0.016
5.2
2 −−
−−
−−
−−
3 0.000
0.0
0.121
4.3
# Points 2 362 −− −− 1 361
# Labs 1 1 1 1
Method Group • Vanadate Oxidation

Mean 0.270 0.288 1.27 1.35 2.68 2.71
SD
CV
1 0.028
10.2
0.027
9.5
2 0.096
7.5
0.103
7.6
3 0.175
6.5
0.196
7.2
# Points 971 59591 860 41343 663 55607
# Labs 35 172 35 140 31 165
Bilirubin, Indirect/BU Calculated mg/dL

Mean −− 0.086 −− 1.15 −− 3.29
SD
CV
1 −−
−−
0.063
73.6
2 −−
−−
0.854
74.1
3 −−
−−
2.43
73.9
# Points −− 64 −− 69 −− 69
# Labs 2 2 2

Mean −− 0.251 −− 1.11 −− 4.12
SD
CV
1 −−
−−
0.120
47.7
2 −−
−−
0.941
84.5
3 −−
−−
2.30
55.8
# Points −− 295 −− 184 −− 332
# Labs 4 2 4
Bilirubin, Indirect/BU Calculated mg/dL

Mean −− 0.308 −− 0.224 −− 5.39
SD
CV
1 −−
−−
0.050
16.2
2 −−
−−
0.003
1.3
3 −−
−−
0.737
13.7
# Points −− 114 −− 2 −− 88
# Labs 2 1 2

Mean −− 0.129 −− −− −− 5.49
SD
CV
1 −−
−−
0.009
7.1
2 −−
−−
−−
−−
3 −−
−−
0.119
2.2
# Points −− 38 −− −− −− 6
# Labs 1 1

Mean −− 0.179 −− 1.13 −− 4.98
SD
CV
1 −−
−−
0.061
34.2
2 −−
−−
0.988
87.0
3 −−
−−
1.62
32.6
# Points −− 596 −− 120 −− 586
# Labs 4 2 4

Mean −− 0.000 −− 1.75 −− −−
SD
CV
1 −−
−−
0.000
−−
2 −−
−−
0.000
0.0
3 −−
−−
−−
−−
# Points −− 1 −− 1 −− −−
# Labs 1 1

Mean −− 0.290 −− −− −− 5.44
SD
CV
1 −−
−−
0.017
5.7
2 −−
−−
−−
−−
3 −−
−−
0.120
2.2
# Points −− 2 −− −− −− 2
# Labs 1 1

Mean −− 0.205 −− 1.12 −− 4.64
SD
CV
1 −−
−−
0.097
47.2
2 −−
−−
0.938
83.4
3 −−
−−
1.94
41.8
# Points −− 1120 −− 376 −− 1083
# Labs 15 8 14
Bilirubin, Indirect/BU Direct measure mg/dL

Mean −− 0.178 −− 2.24 −− 5.35
SD
CV
1 −−
−−
0.067
37.7
2 −−
−−
0.267
11.9
3 −−
−−
0.311
5.8
# Points −− 718 −− 708 −− 642
# Labs 10 8 5

Mean −− 0.263 −− 2.10 −− 5.01
SD
CV
1 −−
−−
0.035
13.4
2 −−
−−
0.088
4.2
3 −−
−−
0.252
5.0
# Points −− 142 −− 327 −− 291
# Labs 2 3 3

Mean −− 0.175 −− 2.04 −− 5.53
SD
CV
1 −−
−−
0.080
45.7
2 −−
−−
0.094
4.6
3 −−
−−
0.374
6.8
# Points −− 356 −− 339 −− 504
# Labs 5 3 6

Mean −− 0.314 −− 1.96 −− 5.46
SD
CV
1 −−
−−
0.104
33.3
2 −−
−−
0.135
6.9
3 −−
−−
0.290
5.3
# Points −− 329 −− 637 −− 643
# Labs 1 3 3

Mean −− 0.159 −− 2.05 −− 5.49
SD
CV
1 −−
−−
0.020
12.6
2 −−
−−
0.104
5.1
3 −−
−−
0.405
7.4
# Points −− 304 −− 263 −− 536
# Labs 2 3 4

Mean −− 0.158 −− 1.99 −− 5.52
SD
CV
1 −−
−−
0.066
41.7
2 −−
−−
0.162
8.1
3 −−
−−
0.404
7.3
# Points −− 193 −− 676 −− 320
# Labs 1 6 2

Mean −− 0.289 −− 1.99 −− 5.54
SD
CV
1 −−
−−
0.031
10.8
2 −−
−−
0.134
6.7
3 −−
−−
0.297
5.4
# Points −− 22 −− 1040 −− 896
# Labs 1 10 10

Mean −− 0.234 −− 2.07 −− 5.69
SD
CV
1 −−
−−
0.054
23.2
2 −−
−−
0.113
5.5
3 −−
−−
0.252
4.4
# Points −− 863 −− 1684 −− 1462
# Labs 9 14 14

Mean −− 0.249 −− 2.04 −− 5.52
SD
CV
1 −−
−−
0.068
27.3
2 −−
−−
0.128
6.3
3 −−
−−
0.282
5.1
# Points −− 388 −− 1048 −− 860
# Labs 8 17 14

Mean −− 0.183 −− 2.00 −− 5.57
SD
CV
1 −−
−−
0.061
33.4
2 −−
−−
0.111
5.5
3 −−
−−
0.226
4.1
# Points −− 1777 −− 1751 −− 2044
# Labs 15 13 15

Mean −− 0.263 −− 2.13 −− 5.79
SD
CV
1 −−
−−
0.073
27.6
2 −−
−−
0.122
5.7
3 −−
−−
0.245
4.2
# Points −− 433 −− 463 −− 440
# Labs 3 7 8

Mean −− 0.206 −− 1.98 −− 5.61
SD
CV
1 −−
−−
0.091
44.2
2 −−
−−
0.133
6.7
3 −−
−−
0.239
4.3
# Points −− 2092 −− 2584 −− 3195
# Labs 22 26 33

Mean −− 0.219 −− 1.94 −− 5.50
SD
CV
1 −−
−−
0.039
17.6
2 −−
−−
0.125
6.5
3 −−
−−
0.222
4.0
# Points −− 1081 −− 2529 −− 2823
# Labs 10 18 21

Mean −− 0.224 −− 2.11 −− 5.70
SD
CV
1 −−
−−
0.075
33.4
2 −−
−−
0.063
3.0
3 −−
−−
0.173
3.0
# Points −− 663 −− 388 −− 702
# Labs 8 5 8

Mean −− 0.124 −− 1.87 −− 5.53
SD
CV
1 −−
−−
0.073
58.9
2 −−
−−
0.089
4.8
3 −−
−−
0.182
3.3
# Points −− 992 −− 886 −− 1062
# Labs 8 6 8

Mean −− 0.179 −− 1.94 −− 5.64
SD
CV
1 −−
−−
0.095
53.0
2 −−
−−
0.107
5.5
3 −−
−−
0.210
3.7
# Points −− 1106 −− 3316 −− 2609
# Labs 17 29 23

Mean −− 0.184 −− 1.90 −− 5.38
SD
CV
1 −−
−−
0.061
33.0
2 −−
−−
0.129
6.7
3 −−
−−
0.237
4.4
# Points −− 561 −− 1785 −− 1357
# Labs 5 12 11

Mean −− 0.151 −− 1.90 −− 5.37
SD
CV
1 −−
−−
0.104
68.9
2 −−
−−
0.132
6.9
3 −−
−−
0.331
6.2
# Points −− 772 −− 2235 −− 2758
# Labs 13 18 19

Mean −− 0.105 −− 1.94 −− 5.57
SD
CV
1 −−
−−
0.107
101.7
2 −−
−−
0.116
6.0
3 −−
−−
0.219
3.9
# Points −− 708 −− 1359 −− 1770
# Labs 8 15 16

Mean −− 0.080 −− 1.89 −− 5.29
SD
CV
1 −−
−−
0.040
49.7
2 −−
−−
0.153
8.1
3 −−
−−
0.264
5.0
# Points −− 64 −− 830 −− 487
# Labs 2 9 4

Mean −− 0.165 −− 1.84 −− 5.34
SD
CV
1 −−
−−
0.085
51.6
2 −−
−−
0.165
8.9
3 −−
−−
0.197
3.7
# Points −− 1625 −− 3051 −− 2781
# Labs 16 20 17

Mean 0.270 0.152 1.75 1.88 −− 5.36
SD
CV
1 0.019
7.0
0.081
53.4
2 0.113
6.4
0.094
5.0
3 −−
−−
0.161
3.0
# Points 11 338 15 944 −− 533
# Labs 1 7 2 16 9

Mean 0.232 0.211 1.82 1.92 5.38 5.32
SD
CV
1 0.021
8.9
0.082
39.0
2 0.139
7.6
0.124
6.4
3 0.132
2.5
0.304
5.7
# Points 79 2092 94 3887 13 2897
# Labs 2 22 3 27 1 22

Mean 0.190 0.198 1.69 1.92 −− 5.40
SD
CV
1 0.000
0.0
0.059
29.6
2 0.000
0.0
0.107
5.6
3 −−
−−
0.165
3.1
# Points 1 571 1 1334 −− 748
# Labs 1 11 1 18 9

Mean 0.450 0.233 −− 1.95 5.73 5.55
SD
CV
1 0.030
6.7
0.146
62.7
2 −−
−−
0.102
5.3
3 0.155
2.7
0.197
3.6
# Points 62 312 −− 547 60 647
# Labs 2 7 8 2 10

Mean 0.234 0.249 1.91 1.94 5.37 5.40
SD
CV
1 0.093
39.8
0.073
29.5
2 0.072
3.8
0.103
5.3
3 0.241
4.5
0.204
3.8
# Points 228 1404 158 1325 207 1389
# Labs 9 19 7 18 7 13

Mean 0.292 0.206 1.86 1.91 5.30 5.28
SD
CV
1 0.014
4.8
0.059
28.5
2 0.102
5.5
0.098
5.1
3 0.148
2.8
0.151
2.9
# Points 21 90 78 230 32 95
# Labs 1 3 3 7 1 1

Mean 0.000 0.000 1.90 1.90 5.40 5.21
SD
CV
1 0.000
−−
0.000
−−
2 0.100
5.3
0.100
5.3
3 0.100
1.9
0.169
3.2
# Points 15 15 13 13 13 97
# Labs 1 1 1 1 1 2

Mean 0.231 0.177 1.91 1.97 5.30 5.41
SD
CV
1 0.057
24.7
0.086
48.6
2 0.090
4.7
0.099
5.0
3 0.213
4.0
0.191
3.5
# Points 125 795 169 754 145 868
# Labs 3 10 5 9 4 8

Mean −− 0.195 1.90 1.90 5.30 5.42
SD
CV
1 −−
−−
0.052
26.5
2 0.100
5.3
0.105
5.6
3 0.200
3.8
0.204
3.8
# Points −− 390 11 548 11 624
# Labs 6 1 8 1 8

Mean −− 0.212 −− −− −− 5.29
SD
CV
1 −−
−−
0.010
4.9
2 −−
−−
−−
−−
3 −−
−−
0.187
3.5
# Points −− 25 −− −− −− 83
# Labs 2 2

Mean 0.270 0.220 1.99 1.96 5.27 5.34
SD
CV
1 0.083
30.6
0.095
43.2
2 0.080
4.0
0.081
4.1
3 0.312
5.9
0.257
4.8
# Points 56 104 70 121 48 93
# Labs 5 5 8 8 5 5

Mean 0.366 0.399 1.70 1.70 5.28 5.41
SD
CV
1 0.078
21.4
0.062
15.6
2 0.122
7.2
0.122
7.2
3 0.359
6.8
0.291
5.4
# Points 81 213 79 100 105 250
# Labs 4 6 5 6 7 8

Mean 0.123 0.271 −− 2.10 5.14 5.19
SD
CV
1 0.008
6.7
0.068
25.2
2 −−
−−
0.080
3.8
3 0.000
0.0
0.128
2.5
# Points 10 60 −− 340 1 393
# Labs 2 3 1 1 3

Mean −− −− 1.87 1.86 5.36 5.32
SD
CV
1 −−
−−
−−
−−
2 0.074
3.9
0.072
3.8
3 0.209
3.9
0.211
4.0
# Points −− −− 69 90 67 89
# Labs 2 2 2 2

Mean −− 0.157 −− 1.95 −− 5.16
SD
CV
1 −−
−−
0.016
10.4
2 −−
−−
0.059
3.1
3 −−
−−
0.154
3.0
# Points −− 121 −− 54 −− 121
# Labs 2 1 2

Mean −− −− −− 1.95 −− 4.97
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.069
3.5
3 −−
−−
0.121
2.4
# Points −− −− −− 197 −− 138
# Labs 1 1

Mean −− 0.120 −− 1.96 −− 5.19
SD
CV
1 −−
−−
0.022
18.4
2 −−
−−
0.055
2.8
3 −−
−−
0.117
2.2
# Points −− 121 −− 120 −− 123
# Labs 1 1 1

Mean −− −− −− 2.13 −− 5.24
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.075
3.5
3 −−
−−
0.147
2.8
# Points −− −− −− 45 −− 42
# Labs 1 1

Mean −− 0.210 −− 2.04 −− 5.11
SD
CV
1 −−
−−
0.010
4.8
2 −−
−−
0.086
4.2
3 −−
−−
0.143
2.8
# Points −− 36 −− 270 −− 240
# Labs 1 2 2

Mean −− 0.429 −− 2.07 −− 5.48
SD
CV
1 −−
−−
0.586
136.7
2 −−
−−
0.091
4.4
3 −−
−−
0.326
6.0
# Points −− 141 −− 267 −− 300
# Labs 2 2 2

Mean −− 0.288 −− 2.02 −− 5.03
SD
CV
1 −−
−−
0.025
8.8
2 −−
−−
0.079
3.9
3 −−
−−
0.163
3.2
# Points −− 133 −− 201 −− 167
# Labs 1 2 2

Mean −− −− −− 2.17 −− 5.21
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.083
3.8
3 −−
−−
0.104
2.0
# Points −− −− −− 105 −− 78
# Labs 1 1

Mean −− 0.377 −− 2.17 −− 5.12
SD
CV
1 −−
−−
0.029
7.8
2 −−
−−
0.092
4.2
3 −−
−−
0.195
3.8
# Points −− 136 −− 321 −− 249
# Labs 1 2 2

Mean −− 0.182 −− 2.02 −− 5.61
SD
CV
1 −−
−−
0.066
35.9
2 −−
−−
0.090
4.4
3 −−
−−
0.209
3.7
# Points −− 519 −− 564 −− 617
# Labs 5 5 5

Mean −− 0.118 −− −− −− 4.83
SD
CV
1 −−
−−
0.036
30.8
2 −−
−−
−−
−−
3 −−
−−
0.103
2.1
# Points −− 144 −− −− −− 130
# Labs 2 2

Mean 0.267 0.198 1.87 1.96 5.36 5.47
SD
CV
1 0.108
40.4
0.103
51.9
2 0.124
6.6
0.149
7.6
3 0.273
5.1
0.283
5.2
# Points 689 23082 757 40042 702 38907
# Labs 31 287 38 392 32 367
Bilirubin, Neonatal/NBIL Calculated mg/dL

Mean −− 0.255 −− −− −− 6.27
SD
CV
1 −−
−−
0.029
11.3
2 −−
−−
−−
−−
3 −−
−−
0.176
2.8
# Points −− 67 −− −− −− 57
# Labs 1 1

Mean −− 0.277 −− −− −− 6.29
SD
CV
1 −−
−−
0.046
16.6
2 −−
−−
−−
−−
3 −−
−−
0.120
1.9
# Points −− 163 −− −− −− 154
# Labs 1 1

Mean −− −− −− 2.40 −− 6.63
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.141
5.9
3 −−
−−
0.193
2.9
# Points −− −− −− 66 −− 70
# Labs 3 3

Mean −− 0.250 −− 3.00 −− 6.19
SD
CV
1 −−
−−
0.083
33.2
2 −−
−−
0.148
4.9
3 −−
−−
0.192
3.1
# Points −− 77 −− 2 −− 69
# Labs 1 1 2

Mean −− 0.214 −− −− −− 6.20
SD
CV
1 −−
−−
0.024
11.3
2 −−
−−
−−
−−
3 −−
−−
0.083
1.3
# Points −− 65 −− −− −− 63
# Labs 1 1

Mean −− 0.620 −− −− −− 6.33
SD
CV
1 −−
−−
0.210
33.9
2 −−
−−
−−
−−
3 −−
−−
0.120
1.9
# Points −− 3 −− −− −− 3
# Labs 2 1

Mean −− 0.240 −− −− −− 6.11
SD
CV
1 −−
−−
0.015
6.3
2 −−
−−
−−
−−
3 −−
−−
0.085
1.4
# Points −− 61 −− −− −− 61
# Labs 1 1

Mean −− 0.352 −− 2.45 −− 6.40
SD
CV
1 −−
−−
0.184
52.3
2 −−
−−
0.147
6.0
3 −−
−−
0.209
3.3
# Points −− 159 −− 251 −− 397
# Labs 2 3 4

Mean −− 0.172 −− −− −− 7.10
SD
CV
1 −−
−−
0.055
32.1
2 −−
−−
−−
−−
3 −−
−−
0.096
1.3
# Points −− 34 −− −− −− 65
# Labs 1 1

Mean −− 0.211 −− −− −− 6.65
SD
CV
1 −−
−−
0.057
27.1
2 −−
−−
−−
−−
3 −−
−−
0.362
5.4
# Points −− 154 −− −− −− 131
# Labs 1 1

Mean −− 0.293 −− −− −− 6.78
SD
CV
1 −−
−−
0.068
23.1
2 −−
−−
−−
−−
3 −−
−−
0.252
3.7
# Points −− 72 −− −− −− 66
# Labs 1 1

Mean −− 0.209 −− −− −− 6.74
SD
CV
1 −−
−−
0.032
15.4
2 −−
−−
−−
−−
3 −−
−−
0.175
2.6
# Points −− 66 −− −− −− 61
# Labs 1 1

Mean −− 0.131 −− 2.54 −− 6.59
SD
CV
1 −−
−−
0.141
107.5
2 −−
−−
0.187
7.4
3 −−
−−
0.176
2.7
# Points −− 64 −− 166 −− 297
# Labs 1 1 2

Mean −− −− −− 2.46 −− 6.52
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.146
5.9
3 −−
−−
0.273
4.2
# Points −− −− −− 138 −− 140
# Labs 1 1

Mean −− 0.209 −− −− −− 6.34
SD
CV
1 −−
−−
0.063
30.2
2 −−
−−
−−
−−
3 −−
−−
0.162
2.5
# Points −− 173 −− −− −− 168
# Labs 1 1

Mean 0.090 0.110 −− 2.41 6.25 6.25
SD
CV
1 0.017
18.9
0.029
26.6
2 −−
−−
0.118
4.9
3 0.100
1.6
0.116
1.9
# Points 32 63 −− 9 32 71
# Labs 1 1 1 1 2

Mean −− −− −− 2.54 −− 6.39
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.123
4.8
3 −−
−−
0.194
3.0
# Points −− −− −− 131 −− 128
# Labs 2 2

Mean −− 0.290 −− −− −− 6.34
SD
CV
1 −−
−−
0.012
4.1
2 −−
−−
−−
−−
3 −−
−−
0.096
1.5
# Points −− 67 −− −− −− 65
# Labs 1 1

Mean −− −− −− −− −− 6.49
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
0.230
3.5
# Points −− −− −− −− −− 31
# Labs 1

Mean −− 0.200 −− −− −− 6.16
SD
CV
1 −−
−−
0.016
8.2
2 −−
−−
−−
−−
3 −−
−−
0.147
2.4
# Points −− 67 −− −− −− 94
# Labs 1 1

Mean −− 0.397 −− −− −− 6.35
SD
CV
1 −−
−−
0.011
2.8
2 −−
−−
−−
−−
3 −−
−−
0.112
1.8
# Points −− 94 −− −− −− 93
# Labs 1 1

Mean −− 0.280 −− −− −− 6.36
SD
CV
1 −−
−−
0.012
4.3
2 −−
−−
−−
−−
3 −−
−−
0.081
1.3
# Points −− 29 −− −− −− 29
# Labs 1 1

Mean −− 0.360 −− −− −− 6.43
SD
CV
1 −−
−−
0.056
15.6
2 −−
−−
−−
−−
3 −−
−−
0.100
1.6
# Points −− 37 −− −− −− 31
# Labs 1 1

Mean −− 0.310 −− −− −− 6.37
SD
CV
1 −−
−−
0.044
14.2
2 −−
−−
−−
−−
3 −−
−−
0.150
2.4
# Points −− 162 −− −− −− 128
# Labs 1 1

Mean 0.090 0.259 −− 2.48 6.25 6.43
SD
CV
1 0.017
18.9
0.105
40.6
2 −−
−−
0.161
6.5
3 0.100
1.6
0.271
4.2
# Points 32 1677 −− 763 32 2472
# Labs 1 22 12 1 33
Bilirubin, Neonatal/NBIL Direct measure mg/dL

APEL BR−501
Mean −− 0.900 −− −− −− 7.81
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
−−
−−
3 −−
−−
0.072
0.9
# Points −− 340 −− −− −− 339
# Labs 1 1
APEL BR−5200
Mean −− 7.93 −− −− −− 7.90
SD
CV
1 −−
−−
0.049
0.6
2 −−
−−
−−
−−
3 −−
−−
0.091
1.2
# Points −− 7 −− −− −− 531
# Labs 1 1
Bilirubin, Neonatal/NBIL Direct measure mg/dL

Mean −− 1.04 −− −− −− 7.86
SD
CV
1 −−
−−
0.990
95.0
2 −−
−−
−−
−−
3 −−
−−
0.097
1.2
# Points −− 347 −− −− −− 864
# Labs 2 2
Bilirubin, Neonatal/NBIL Photometric mg/dL

das NEO−BIL Plus
Mean −− 1.42 −− −− −− 8.57
SD
CV
1 −−
−−
0.246
17.3
2 −−
−−
−−
−−
3 −−
−−
0.748
8.7
# Points −− 513 −− −− −− 513
# Labs 2 2
Method Group • Photometric

Mean −− 1.42 −− −− −− 8.57
SD
CV
1 −−
−−
0.246
17.3
2 −−
−−
−−
−−
3 −−
−−
0.748
8.7
# Points −− 513 −− −− −− 513
# Labs 2 2
Bilirubin, Total/TBIL Calculated mg/dL

Mean −− 0.032 −− −− −− 0.422
SD
CV
1 −−
−−
0.004
13.5
2 −−
−−
−−
−−
3 −−
−−
0.017
4.0
# Points −− 230 −− −− −− 223
# Labs 1 1

Mean −− −− −− 2.86 −− 7.18
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.069
2.4
3 −−
−−
0.122
1.7
# Points −− −− −− 372 −− 377
# Labs 2 2

Mean −− −− −− 2.89 −− 7.16
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.094
3.2
3 −−
−−
0.209
2.9
# Points −− −− −− 1157 −− 1156
# Labs 3 3

Mean −− 0.526 −− 2.66 −− 6.69
SD
CV
1 −−
−−
0.011
2.0
2 −−
−−
0.045
1.7
3 −−
−−
0.123
1.8
# Points −− 44 −− 44 −− 44
# Labs 1 1 1

Mean −− 0.036 −− 0.185 −− 0.424
SD
CV
1 −−
−−
0.006
15.6
2 −−
−−
0.009
4.9
3 −−
−−
0.027
6.3
# Points −− 519 −− 67 −− 510
# Labs 1 1 1

Mean −− 0.030 −− −− −− 0.446
SD
CV
1 −−
−−
0.006
19.6
2 −−
−−
−−
−−
3 −−
−−
0.026
5.8
# Points −− 21 −− −− −− 44
# Labs 1 1
Bilirubin, Total/TBIL Calculated mg/dL

Mean −− 0.091 −− 2.65 −− 4.97
SD
CV
1 −−
−−
0.149
162.5
2 −−
−−
0.761
28.7
3 −−
−−
3.15
63.3
# Points −− 916 −− 1832 −− 2479
# Labs 6 9 11
Bilirubin, Total/TBIL Diazonium Ion mg/dL

Mean 0.760 0.706 −− 2.89 −− 7.24
SD
CV
1 0.000
0.0
0.053
7.5
2 −−
−−
0.136
4.7
3 −−
−−
0.162
2.2
# Points 1 28 −− 18 −− 5
# Labs 1 1 1 1

Mean 0.540 0.558 2.70 2.84 6.67 7.19
SD
CV
1 0.055
10.2
0.052
9.3
2 0.157
5.8
0.179
6.3
3 0.385
5.8
0.414
5.8
# Points 1717 68847 1352 41043 839 64780
# Labs 66 240 57 155 35 190
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH TBili2, REF 04T09

Mean −− 0.520 −− −− −− 7.06
SD
CV
1 −−
−−
0.039
7.4
−−
−−
2 −−
−−
3 −−
−−
0.179
2.5
# Points −− 107 −− −− −− 109
# Labs 2 2
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH Total Bilirubin REF 6L45
Mean 0.474 0.514 2.32 2.49 −− −−
SD
CV
1 0.030
6.3
0.046
9.0
0.126
5.4
2 0.261
10.5
3 −−
−−
−−
−−
# Points 18 201 18 202 −− −−
# Labs 1 1 1 1
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c Bili Total 04V51/Bili D 07P97
Mean −− 0.571 −− −− −− 7.68
SD
CV
1 −−
−−
0.019
3.3
2−−
−−
−−
−−
3 −−
−−
0.159
2.1
# Points −− 77 −− −− −− 77
# Labs 1 1
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c Bili Total, REF 04V51
Mean −− 0.566 −− −− −− 7.47
SD
CV
1 −−
−−
0.074
13.1
2−−
−−
−−
−−
3 −−
−−
0.506
6.8
# Points −− 232 −− −− −− 219
# Labs 2 1
Abbott ARCHITECT/Alinity (c, i, ci models) • Reagent, Alternate Calibration − Shift DOWN

Mean 0.544 0.556 2.63 2.64 7.02 7.33
SD
CV
1 0.052
9.5
0.042
7.6
2
0.080
3.0
0.220
8.3
3 0.418
6.0
0.468
6.4
# Points 171 2625 28 224 143 2399
# Labs 4 5 1 2 3 3

Mean 0.590 0.605 2.79 2.89 6.95 7.30
SD
CV
1 0.056
9.4
0.041
6.7
2 0.123
4.4
0.126
4.4
3 0.398
5.7
0.359
4.9
# Points 81 3122 57 1720 75 3900
# Labs 3 11 2 8 3 14
ERBA XL−640
Mean −− 0.521 −− 3.08 −− −−
SD
CV
1 −−
−−
0.048
9.2
2 −−
−−
0.133
4.3
3 −−
−−
−−
−−
# Points −− 40 −− 52 −− −−
# Labs 1 1
Bilirubin, Total/TBIL Diazonium Ion mg/dL

Mean −− 0.552 −− 2.75 −− −−
SD
CV
1 −−
−−
0.029
5.3
2 −−
−−
0.093
3.4
3 −−
−−
−−
−−
# Points −− 50 −− 92 −− −−
# Labs 1 2
Fuji Dri−Chem Series • Fuji Dri−Chem TBIL−PIII, REF 897N203627A

Mean −− 0.567 −− 2.49 −− −−
SD
CV
1 −−
−−
0.049
8.6
2−−
−−
0.115
4.6
3 −−
−−
−−
−−
# Points −− 18 −− 20 −− −−
# Labs 2 2

Mean 0.467 0.466 2.62 2.63 6.49 6.60
SD
CV
1 0.018
3.8
0.029
6.3
2 0.048
1.8
0.088
3.3
3 0.112
1.7
0.213
3.2
# Points 41 1880 41 2685 41 2901
# Labs 1 4 1 4 1 6
Roche cobas c 303/503 • Roche BILT3, REF 08056960

Mean −− 0.476 −− 2.61 −− 6.53
SD
CV
1 −−
−−
0.020
4.2
2 −−
−−
0.075
2.9
3 −−
−−
0.130
2.0
# Points −− 590 −− 922 −− 470
# Labs 1 1 1

Mean 0.444 0.532 −− 2.76 6.98 7.22
SD
CV
1 0.079
17.7
0.047
8.7
2 −−
−−
0.129
4.7
3 0.426
6.1
0.276
3.8
# Points 38 1575 −− 97 36 1532
# Labs 2 7 1 2 7

Mean −− −− 2.62 2.64 −− −−
SD
CV
1 −−
−−
−−
−−
2 0.104
4.0
0.110
4.2
3 −−
−−
−−
−−
# Points −− −− 20 28 −− −−
# Labs 1 1
Method Group • Diazonium Ion

Mean 0.538 0.556 2.69 2.82 6.74 7.18
SD
CV
1 0.058
10.8
0.054
9.7
2 0.159
5.9
0.184
6.5
3 0.411
6.1
0.425
5.9
# Points 2067 79395 1516 47097 1134 76392
# Labs 78 279 63 179 44 226
Bilirubin, Total/TBIL Diazonium Ion, Blanked (Roche) mg/dL

Mean −− 0.607 −− 2.95 −− 7.08
SD
CV
1 −−
−−
0.053
8.7
2 −−
−−
0.203
6.9
3 −−
−−
0.301
4.3
# Points −− 495 −− 495 −− 488
# Labs 2 2 2

Mean −− 0.614 −− −− −− 7.39
SD
CV
1 −−
−−
0.012
2.0
2 −−
−−
−−
−−
3 −−
−−
0.138
1.9
# Points −− 209 −− −− −− 188
# Labs 1 1
Mindray BS Series
Mean −− 0.521 −− 6.91 −− −−
SD
CV
1 −−
−−
0.013
2.6
2 −−
−−
0.124
1.8
3 −−
−−
−−
−−
# Points −− 234 −− 232 −− −−
# Labs 1 1

Mindray CL Series
Mean −− −− −− 2.70 −− 6.86
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.059
2.2
3 −−
−−
0.130
1.9
# Points −− −− −− 87 −− 88
# Labs 1 1

Mean 0.474 0.485 2.62 2.67 6.56 6.69
SD
CV
1 0.026
5.5
0.028
5.8
2 0.108
4.1
0.104
3.9
3 0.191
2.9
0.203
3.0
# Points 3041 95268 248 38496 2926 95626
# Labs 50 191 8 104 47 197
Roche cobas 6000/8000/c 311 • 3rd Generation

Mean −− 0.502 −− −− −− 7.04
SD
CV
1 −−
−−
0.022
4.3
2 −−
−−
−−
−−
3 −−
−−
0.200
2.8
# Points −− 947 −− −− −− 997
# Labs 5 5

Mean −− 0.484 −− 2.70 −− 6.69
SD
CV
1 −−
−−
0.027
5.6
2
−−
−−
0.112
4.1
3 −−
−−
0.246
3.7
# Points −− 349 −− 416 −− 290
# Labs 3 2 3

Mean 0.454 0.467 2.44 2.58 6.31 6.50
SD
CV
1 0.020
4.4
0.027
5.9
2 0.049
2.0
0.097
3.7
3 0.113
1.8
0.209
3.2
# Points 139 6335 90 5040 98 6175
# Labs 5 19 3 13 4 18
Roche cobas c 303/503 • Alternate Formulation/Standardization

Mean 0.446 0.455 2.50 2.50 6.25 6.29
SD
CV
1 0.017
3.8
0.016
3.6
2
0.069
2.7
0.057
2.3
3 0.125
2.0
0.109
1.7
# Points 58 911 62 1004 50 767
# Labs 2 2 2 2 2 2
Roche cobas c 303/503 • Roche BILT2

Mean −− 0.440 −− −− −− 6.21
SD
CV
1 −−
−−
0.014
3.2
2 −−
−−
−−
−−
3 −−
−−
0.205
3.3
# Points −− 2 −− −− −− 2
# Labs 1 1

Mean 0.457 0.462 2.40 2.55 6.17 6.35
SD
CV
1 0.021
4.7
0.027
5.9
2 0.063
2.6
0.063
2.5
3 0.106
1.7
0.210
3.3
# Points 179 9896 28 2792 155 9958
# Labs 6 31 1 7 5 30

Mean 0.458 0.466 2.55 2.61 6.53 6.65
SD
CV
1 0.014
3.2
0.018
3.8
2 0.054
2.1
0.068
2.6
3 0.137
2.1
0.148
2.2
# Points 108 1412 109 1674 14 582
# Labs 2 3 2 3 1 3

Mean 0.484 0.486 2.67 2.66 6.46 6.60
SD
CV
1 0.021
4.4
0.029
6.0
2 0.040
1.5
0.074
2.8
3 0.160
2.5
0.211
3.2
# Points 90 3665 32 830 90 3642
# Labs 3 12 1 2 3 12

Roche cobas Integra / c 111 • 3rd Generation
Mean −− 0.507 −− −− −− 6.82
SD
CV
1 −−
−−
0.017
3.4
2 −−
−−
−−
−−
3 −−
−−
0.182
2.7
# Points −− 125 −− −− −− 126
# Labs 1 1

Mean −− 0.553 −− 2.71 −− 6.86
SD
CV
1 −−
−−
0.037
6.7
2 −−
−−
0.095
3.5
3 −−
−−
0.181
2.6
# Points −− 222 −− 222 −− 222
# Labs 1 1 1
Mean −− −− −− 2.92 −− 7.34
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.179
6.1
3 −−
−−
0.428
5.8
# Points −− −− −− 369 −− 367
# Labs 1 1
Method Group • Diazonium Ion, Blanked (Roche)

Mean 0.472 0.483 2.56 2.68 6.53 6.66
SD
CV
1 0.026
5.5
0.031
6.4
2 0.115
4.5
0.311
11.6
3 0.207
3.2
0.239
3.6
# Points 3557 119K 507 50237 3283 118K
# Labs 66 268 15 135 60 273
Bilirubin, Total/TBIL Dichloroaniline mg/dL

Mean −− 0.601 −− 3.09 −− 7.75
SD
CV
1 −−
−−
0.056
9.3
2 −−
−−
0.181
5.9
3 −−
−−
0.416
5.4
# Points −− 247 −− 211 −− 247
# Labs 2 1 2

Mean −− 0.559 −− 3.10 −− 7.65
SD
CV
1 −−
−−
0.066
11.8
2 −−
−−
0.106
3.4
3 −−
−−
0.244
3.2
# Points −− 105 −− 107 −− 107
# Labs 1 1 1
Method Group • Dichloroaniline

Mean −− 0.566 −− 3.10 −− 7.72
SD
CV
1 −−
−−
0.081
14.4
2 −−
−−
0.238
7.7
3 −−
−−
0.375
4.9
# Points −− 420 −− 386 −− 354
# Labs 4 3 3
Bilirubin, Total/TBIL Diphylline, Diazonium Salt−VITROS mg/dL

Mean 0.604 0.559 2.92 2.82 −− 6.93
SD
CV
1 0.030
5.0
0.047
8.4
2 0.000
0.0
0.057
2.0
3 −−
−−
0.109
1.6
# Points 6 209 5 117 −− 45
# Labs 1 3 1 2 1

Mean 0.530 0.598 2.82 3.10 7.67 7.46
SD
CV
1 0.040
7.5
0.087
14.6
2 0.165
5.8
0.180
5.8
3 0.170
2.2
0.386
5.2
# Points 15 4555 3 2785 15 3708
# Labs 1 41 1 23 1 28

Mean −− 0.521 −− −− −− 7.61
SD
CV
1 −−
−−
0.058
11.2
2 −−
−−
−−
−−
3 −−
−−
0.513
6.7
# Points −− 277 −− −− −− 225
# Labs 4 4

Mean 0.461 0.537 2.64 2.81 6.99 7.55
SD
CV
1 0.073
15.8
0.056
10.4
2 0.138
5.2
0.233
8.3
3 0.400
5.7
0.433
5.7
# Points 18 1528 23 661 22 1423
# Labs 1 14 1 5 1 12

Mean −− 0.513 −− 2.97 7.92 7.60
SD
CV
1 −−
−−
0.065
12.7
2 −−
−−
0.127
4.3
3 0.205
2.6
0.306
4.0
# Points −− 3507 −− 973 34 3342
# Labs 25 11 1 26

Mean 0.604 0.531 −− 2.90 7.45 7.26
SD
CV
1 0.068
11.3
0.073
13.7
2 −−
−−
0.220
7.6
3 0.236
3.2
0.321
4.4
# Points 22 3500 −− 1020 20 3500
# Labs 1 31 9 1 30

Mean −− 0.563 −− 3.08 −− 7.78
SD
CV
1 −−
−−
0.065
11.5
2 −−
−−
0.171
5.6
3 −−
−−
0.418
5.4
# Points −− 3073 −− 1170 −− 2927
# Labs 38 13 31

Mean 0.530 0.547 2.82 3.01 7.50 7.45
SD
CV
1 0.061
11.5
0.067
12.2
2 0.114
4.0
0.168
5.6
3 0.340
4.5
0.324
4.3
# Points 73 3184 30 1267 69 3001
# Labs 3 26 1 10 3 24

Mean 0.614 0.563 3.19 3.15 7.81 7.76
SD
CV
1 0.094
15.3
0.074
13.2
2 0.097
3.0
0.259
8.2
3 0.403
5.2
0.453
5.8
# Points 37 3269 26 1623 37 2931
# Labs 3 32 2 14 3 26

Mean 0.552 0.561 2.91 2.95 8.17 7.67
SD
CV
1 0.056
10.2
0.064
11.4
2 0.125
4.3
0.189
6.4
3 0.578
7.1
0.486
6.3
# Points 127 3669 64 1762 123 2776
# Labs 6 29 3 14 4 24

Mean 0.557 0.538 −− 3.03 −− 7.65
SD
CV
1 0.051
9.1
0.054
10.1
2 −−
−−
0.155
5.1
3 −−
−−
0.490
6.4
# Points 21 1114 −− 786 −− 772
# Labs 1 17 12 11

Mean 0.521 0.506 2.51 2.67 −− 7.81
SD
CV
1 0.022
4.2
0.057
11.3
2 0.105
4.2
0.248
9.3
3 −−
−−
0.342
4.4
# Points 24 400 24 57 −− 336
# Labs 1 7 1 2 5

Mean 0.619 0.617 3.00 3.02 7.68 7.61
SD
CV
1 0.073
11.9
0.077
12.6
2 0.151
5.0
0.160
5.3
3 0.354
4.6
0.337
4.4
# Points 557 2117 309 1182 355 1633
# Labs 25 33 15 19 17 24

Mean 0.612 0.613 2.92 2.94 7.52 7.30
SD
CV
1 0.067
10.9
0.067
11.0
2 0.085
2.9
0.094
3.2
3 0.249
3.3
0.352
4.8
# Points 97 118 34 44 89 178
# Labs 4 4 2 2 3 4

Mean 0.614 0.474 3.10 2.87 7.65 7.47
SD
CV
1 0.047
7.6
0.082
17.3
2 0.162
5.2
0.144
5.0
3 0.400
5.2
0.308
4.1
# Points 116 1019 75 885 192 1064
# Labs 9 21 7 16 9 19

Mean 0.531 0.506 2.88 2.91 7.45 7.44
SD
CV
1 0.055
10.3
0.074
14.6
2 0.093
3.2
0.141
4.9
3 0.215
2.9
0.329
4.4
# Points 76 3850 75 1951 75 3849
# Labs 2 25 2 16 2 25

Mean 0.580 0.528 −− 2.88 7.62 7.47
SD
CV
1 0.030
5.2
0.061
11.6
2 −−
−−
0.143
5.0
3 0.260
3.4
0.384
5.1
# Points 31 2814 −− 1469 31 2863
# Labs 1 21 12 1 19

Mean 0.516 0.516 −− 2.80 7.18 7.20
SD
CV
1 0.034
6.5
0.069
13.3
2 −−
−−
0.137
4.9
3 0.306
4.3
0.352
4.9
# Points 24 2496 −− 1186 21 2217
# Labs 1 16 10 1 16

Mean 0.552 0.538 2.91 2.88 7.57 7.45
SD
CV
1 0.058
10.5
0.080
14.9
2 0.101
3.5
0.160
5.6
3 0.270
3.6
0.369
5.0
# Points 222 2172 87 818 167 1914
# Labs 10 15 5 8 8 13

Mean 0.610 0.607 3.03 3.03 7.49 7.51
SD
CV
1 0.067
11.0
0.069
11.4
2 0.123
4.1
0.121
4.0
3 0.222
3.0
0.232
3.1
# Points 45 46 42 43 22 23
# Labs 4 5 4 5 3 4

Mean −− 0.641 −− 2.85 −− 6.99
SD
CV
1 −−
−−
0.032
5.0
2 −−
−−
0.110
3.9
3 −−
−−
0.195
2.8
# Points −− 106 −− 72 −− 169
# Labs 1 1 2

Mean −− 0.554 −− 3.00 −− 7.34
SD
CV
1 −−
−−
0.068
12.3
2 −−
−−
0.100
3.3
3 −−
−−
0.164
2.2
# Points −− 170 −− 19 −− 253
# Labs 4 1 4

Mean −− 0.428 −− −− −− 6.82
SD
CV
1 −−
−−
0.016
3.8
2 −−
−−
−−
−−
3 −−
−−
0.164
2.4
# Points −− 83 −− −− −− 78
# Labs 1 2

Mean −− 0.505 −− −− −− 6.88
SD
CV
1 −−
−−
0.037
7.3
2 −−
−−
−−
−−
3 −−
−−
0.101
1.5
# Points −− 70 −− −− −− 70
# Labs 1 1

Mean −− 0.497 −− 3.11 −− 7.97
SD
CV
1 −−
−−
0.053
10.6
2 −−
−−
0.127
4.1
3 −−
−−
0.372
4.7
# Points −− 180 −− 8 −− 104
# Labs 2 1 1

Mean −− 0.505 −− −− −− 7.18
SD
CV
1 −−
−−
0.030
6.0
2 −−
−−
−−
−−
3 −−
−−
0.138
1.9
# Points −− 107 −− −− −− 106
# Labs 1 1

Mean −− 0.531 −− −− −− 7.13
SD
CV
1 −−
−−
0.022
4.1
2 −−
−−
−−
−−
3 −−
−−
0.126
1.8
# Points −− 78 −− −− −− 78
# Labs 1 1

Mean −− 0.547 −− 2.99 −− 7.47
SD
CV
1 −−
−−
0.037
6.8
2 −−
−−
0.095
3.2
3 −−
−−
0.137
1.8
# Points −− 131 −− 23 −− 132
# Labs 2 1 2

Mean −− 0.548 −− 2.94 −− 7.01
SD
CV
1 −−
−−
0.043
7.8
2 −−
−−
0.103
3.5
3 −−
−−
0.238
3.4
# Points −− 265 −− 125 −− 268
# Labs 2 1 2

Mean −− 0.600 −− −− −− 7.57
SD
CV
1 −−
−−
0.036
6.0
2 −−
−−
−−
−−
3 −−
−−
0.162
2.1
# Points −− 67 −− −− −− 95
# Labs 1 1

Mean −− 0.604 −− 2.97 −− 7.08
SD
CV
1 −−
−−
0.031
5.1
2 −−
−−
0.087
2.9
3 −−
−−
0.173
2.4
# Points −− 232 −− 128 −− 227
# Labs 2 1 2

Mean −− 0.658 −− 3.07 −− 7.41
SD
CV
1 −−
−−
0.036
5.4
2 −−
−−
0.099
3.2
3 −−
−−
0.221
3.0
# Points −− 201 −− 66 −− 199
# Labs 2 1 2

Mean −− 0.545 −− 6.18 −− 7.09
SD
CV
1 −−
−−
0.053
9.8
2 −−
−−
7.33
118.6
3 −−
−−
0.194
2.7
# Points −− 282 −− 199 −− 276
# Labs 2 1 2

Mean −− 0.487 −− −− −− 7.05
SD
CV
1 −−
−−
0.034
7.0
2 −−
−−
−−
−−
3 −−
−−
0.237
3.4
# Points −− 93 −− −− −− 99
# Labs 1 1

Mean −− 0.537 −− 3.00 −− 7.39
SD
CV
1 −−
−−
0.067
12.5
2 −−
−−
0.133
4.4
3 −−
−−
0.324
4.4
# Points −− 1805 −− 283 −− 1859
# Labs 12 3 12

Mean −− 0.578 −− −− −− 7.17
SD
CV
1 −−
−−
0.030
5.3
2 −−
−−
−−
−−
3 −−
−−
0.197
2.7
# Points −− 123 −− −− −− 122
# Labs 1 1

Mean −− 0.542 −− 2.98 −− 7.42
SD
CV
1 −−
−−
0.078
14.3
2 −−
−−
0.193
6.5
3 −−
−−
0.459
6.2
# Points −− 5607 −− 2666 −− 4615
# Labs 44 25 40

Mean −− 0.576 −− −− −− 7.25
SD
CV
1 −−
−−
0.034
5.9
2 −−
−−
−−
−−
3 −−
−−
0.241
3.3
# Points −− 219 −− −− −− 218
# Labs 4 4

Mean −− 0.509 −− 2.92 −− 7.46
SD
CV
1 −−
−−
0.072
14.2
2 −−
−−
0.132
4.5
3 −−
−−
0.335
4.5
# Points −− 4030 −− 1522 −− 4294
# Labs 35 15 35

Mean −− 0.559 −− 3.06 −− 7.03
SD
CV
1 −−
−−
0.059
10.6
2 −−
−−
0.134
4.4
3 −−
−−
0.428
6.1
# Points −− 323 −− 349 −− 304
# Labs 4 3 4

Mean −− 0.506 −− 2.92 −− 7.46
SD
CV
1 −−
−−
0.070
13.9
2 −−
−−
0.152
5.2
3 −−
−−
0.321
4.3
# Points −− 8516 −− 2944 −− 7947
# Labs 76 32 71

Mean −− 0.533 −− 2.85 −− 7.26
SD
CV
1 −−
−−
0.067
12.6
2 −−
−−
0.245
8.6
3 −−
−−
0.376
5.2
# Points −− 2840 −− 661 −− 2838
# Labs 35 10 35

Mean −− 0.594 −− 2.97 −− 7.51
SD
CV
1 −−
−−
0.069
11.7
2 −−
−−
0.156
5.3
3 −−
−−
0.317
4.2
# Points −− 4252 −− 2298 −− 3727
# Labs 32 15 30

Mean −− 0.499 −− −− −− 7.35
SD
CV
1 −−
−−
0.025
5.1
2 −−
−−
−−
−−
3 −−
−−
0.227
3.1
# Points −− 134 −− −− −− 126
# Labs 2 2

Mean −− 0.572 −− −− −− 7.83
SD
CV
1 −−
−−
0.057
10.0
2 −−
−−
−−
−−
3 −−
−−
0.245
3.1
# Points −− 87 −− −− −− 89
# Labs 1 1
Method Group • Diphylline, Diazonium Salt−VITROS

Mean 0.586 0.541 2.95 2.99 7.66 7.47
SD
CV
1 0.075
12.7
0.078
14.5
2 0.181
6.1
0.667
22.3
3 0.417
5.4
0.399
5.3
# Points 1511 71854 797 31204 1272 66342
# Labs 74 670 45 313 58 600
Bilirubin, Total/TBIL Direct measure mg/dL

Mean −− 0.525 −− 2.89 −− 6.88
SD
CV
1 −−
−−
0.056
10.6
2 −−
−−
0.143
4.9
3 −−
−−
0.416
6.1
# Points −− 150 −− 143 −− 153
# Labs 1 1 1

Mean −− 0.720 −− 2.88 −− 7.91
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
0.241
8.4
3 −−
−−
0.000
0.0
# Points −− 1 −− 7 −− 1
# Labs 1 2 1

Mean −− 0.613 −− 3.14 −− −−
SD
CV
1 −−
−−
0.099
16.2
2 −−
−−
0.343
10.9
3 −−
−−
−−
−−
# Points −− 72 −− 70 −− −−
# Labs 2 2

Mean 0.429 0.455 2.72 2.75 −− −−
SD
CV
1 0.091
21.2
0.065
14.3
2 0.116
4.3
0.123
4.5
3 −−
−−
−−
−−
# Points 37 121 37 121 −− −−
# Labs 2 2 2 2

Mean 0.429 0.519 2.72 2.89 −− 6.88
SD
CV
1 0.091
21.2
0.091
17.5
2 0.116
4.3
0.243
8.4
3 −−
−−
0.423
6.1
# Points 37 344 37 341 −− 154
# Labs 2 6 2 7 2
Bilirubin, Total/TBIL DPD mg/dL

Mean 0.583 0.599 2.83 3.00 7.05 7.23
SD
CV
1 0.039
6.7
0.033
5.5
2 0.164
5.8
0.138
4.6
3 0.278
3.9
0.267
3.7
# Points 1954 101K 1626 52940 1059 102K
# Labs 68 312 53 177 36 286
Beckman Coulter AU Series • Alternate Calibration

Mean 0.598 0.595 −− −− 7.17 7.28
SD
CV
1 0.008
1.3
0.013
2.3
2 −−
−−
−−
−−
3 0.076
1.1
0.137
1.9
# Points 21 505 −− −− 21 484
# Labs 1 1 1 1

Mean −− 0.636 −− 3.14 −− 7.46
SD
CV
1 −−
−−
0.015
2.3
2 −−
−−
0.075
2.4
3 −−
−−
0.195
2.6
# Points −− 621 −− 930 −− 615
# Labs 5 7 5

Mean −− −− −− 3.13 −− 7.80
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.118
3.8
3 −−
−−
0.311
4.0
# Points −− −− −− 336 −− 336
# Labs 1 1
Dirui CS Series • Wako

Mean −− −− 2.92 2.97 7.30 7.44
SD
CV
1 −−
−−
−−
−−
2 0.056
1.9
0.100
3.4
3 0.115
1.6
0.215
2.9
# Points −− −− 32 136 32 138
# Labs 1 1 1 1

Mean 0.559 0.567 2.65 2.72 −− −−
SD
CV
1 0.022
3.9
0.022
3.8
2 0.070
2.7
0.119
4.4
3 −−
−−
−−
−−
# Points 10 255 10 188 −− −−
# Labs 1 1 1 1

Mean −− 0.594 −− −− −− −−
SD
CV
1 −−
−−
0.040
6.7
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 32 −− −− −− −−
# Labs 1

Mean −− 0.684 −− −− −− 8.34
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− 1 −− −− −− 1
# Labs 1 1

Mean −− −− −− 2.63 −− 6.88
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.046
1.8
3 −−
−−
0.107
1.6
# Points −− −− −− 148 −− 148
# Labs 1 1

Mean −− −− −− 2.46 −− 6.09
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.090
3.7
3 −−
−−
0.152
2.5
# Points −− −− −− 140 −− 141
# Labs 1 1
Bilirubin, Total/TBIL DPD mg/dL

Mean 0.458 0.460 2.48 2.48 −− −−
SD
CV
1 0.020
4.4
0.019
4.2
2 0.079
3.2
0.085
3.4
3 −−
−−
−−
−−
# Points 113 172 112 171 −− −−
# Labs 2 2 2 2

Mean −− 0.536 −− 2.59 −− 6.53
SD
CV
1 −−
−−
0.030
5.6
2 −−
−−
0.102
3.9
3 −−
−−
0.231
3.5
# Points −− 358 −− 358 −− 358
# Labs 2 2 2

Mean −− −− −− 3.00 −− 7.21
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.071
2.4
3 −−
−−
0.277
3.8
# Points −− −− −− 253 −− 253
# Labs 1 1

Mean −− −− −− 3.10 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.038
1.2
3 −−
−−
−−
−−
# Points −− −− −− 24 −− −−
# Labs 1
Method Group • DPD

Mean 0.576 0.599 2.81 3.00 7.05 7.23
SD
CV
1 0.048
8.2
0.034
5.7
2 0.181
6.4
0.148
4.9
3 0.278
3.9
0.275
3.8
# Points 2077 102K 1780 55447 1091 104K
# Labs 71 323 57 194 37 298
Bilirubin, Total/TBIL Enzymatic mg/dL

Mean −− 0.728 −− −− −− 7.13
SD
CV
1 −−
−−
0.062
8.4
2 −−
−−
−−
−−
3 −−
−−
0.232
3.3
# Points −− 36 −− −− −− 73
# Labs 2 1

Mean −− 0.538 −− 2.78 −− 7.00
SD
CV
1 −−
−−
0.028
5.2
2 −−
−−
0.052
1.9
3 −−
−−
0.112
1.6
# Points −− 63 −− 58 −− 55
# Labs 2 2 2

Mean 0.574 0.586 −− 3.04 7.23 7.24
SD
CV
1 0.051
8.9
0.041
7.0
2 −−
−−
0.085
2.8
3 0.266
3.7
0.284
3.9
# Points 65 1459 −− 14 63 1379
# Labs 2 3 1 2 3

Mean −− 0.591 −− 2.95 −− 7.28
SD
CV
1 −−
−−
0.012
2.0
2 −−
−−
0.048
1.6
3 −−
−−
0.114
1.6
# Points −− 2524 −− 2441 −− 2408
# Labs 2 2 2

Mean −− 0.690 −− 3.16 −− 7.60
SD
CV
1 −−
−−
0.114
16.5
2 −−
−−
0.140
4.5
3 −−
−−
0.216
2.8
# Points −− 480 −− 3 −− 459
# Labs 3 1 2
Bilirubin, Total/TBIL Enzymatic mg/dL

Hitachi Chemistry Series • Mitsubishi Kagaku Iatron, Inc.
Mean −− 0.572 −− −− −− −−
SD
CV
1 −−
−−
0.013
2.3
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 63 −− −− −− −−
# Labs 1

Mean −− 0.530 −− −− −− 7.47
SD
CV
1 −−
−−
0.063
11.9
2 −−
−−
−−
−−
3 −−
−−
0.314
4.2
# Points −− 415 −− −− −− 412
# Labs 1 1

Mean 0.574 0.594 −− 2.95 7.23 7.31
SD
CV
1 0.051
8.9
0.060
10.0
2 −−
−−
0.055
1.9
3 0.266
3.7
0.240
3.3
# Points 65 5040 −− 2516 63 4786
# Labs 2 14 6 2 11
Bilirubin, Total/TBIL Evelyn Malloy mg/dL

Mean 0.531 0.530 2.66 2.72 6.77 7.29
SD
CV
1 0.071
13.4
0.064
12.2
2 0.303
11.4
0.298
10.9
3 0.303
4.5
0.588
8.1
# Points 43 368 29 270 5 44
# Labs 2 2 2 2 1 2

Mean −− 0.482 −− 2.68 −− 6.66
SD
CV
1 −−
−−
0.020
4.1
2 −−
−−
0.061
2.3
3 −−
−−
0.144
2.2
# Points −− 1422 −− 1412 −− 1405
# Labs 2 2 2
Method Group • Evelyn Malloy

Mean 0.531 0.492 2.66 2.68 6.77 6.68
SD
CV
1 0.071
13.4
0.039
8.0
2 0.303
11.4
0.133
4.9
3 0.303
4.5
0.205
3.1
# Points 43 1790 29 1682 5 1449
# Labs 2 4 2 4 1 4
Bilirubin, Total/TBIL Hypochlorite oxidation mg/dL

Mean 0.651 0.621 3.08 3.11 8.13 8.08
SD
CV
1 0.034
5.2
0.040
6.5
2 0.314
10.2
0.252
8.1
3 0.337
4.2
0.228
2.8
# Points 62 184 62 184 62 184
# Labs 2 2 2 2 2 2

Mean 0.633 0.588 3.08 2.88 7.99 7.28
SD
CV
1 0.013
2.1
0.059
10.0
2 0.122
4.0
0.273
9.5
3 0.074
0.9
0.691
9.5
# Points 31 446 31 446 31 438
# Labs 1 3 1 3 1 3
Method Group • Hypochlorite oxidation

Mean 0.645 0.597 3.08 2.95 8.08 7.52
SD
CV
1 0.030
4.6
0.056
9.4
2 0.265
8.6
0.286
9.7
3 0.286
3.5
0.696
9.3
# Points 93 630 93 630 93 622
# Labs 3 5 3 5 3 5
Bilirubin, Total/TBIL Jendrassik Grof mg/dL

Mean 0.554 0.574 −− −− 6.85 7.25
SD
CV
1 0.050
9.1
0.064
11.1
2 −−
−−
−−
−−
3 0.127
1.9
0.220
3.0
# Points 48 642 −− −− 48 485
# Labs 1 1 1 1

Mean −− 0.587 −− 2.95 −− 7.08
SD
CV
1 −−
−−
0.040
6.8
2 −−
−−
0.125
4.2
3 −−
−−
0.355
5.0
# Points −− 1470 −− 1352 −− 1487
# Labs 4 3 5

Mean 0.800 0.713 −− 3.25 7.45 7.63
SD
CV
1 0.100
12.5
0.121
16.9
2 −−
−−
0.161
5.0
3 0.198
2.7
0.245
3.2
# Points 26 9689 −− 3266 64 9519
# Labs 1 31 11 2 30
ILab Series
Mean 0.482 0.488 3.11 3.11 −− −−
SD
CV
1 0.040
8.4
0.056
11.4
2 0.030
1.0
0.122
3.9
3 −−
−−
−−
−−
# Points 11 50 11 50 −− −−
# Labs 1 1 1 1

Mean −− 0.461 −− −− −− 6.35
SD
CV
1 −−
−−
0.048
10.5
2 −−
−−
−−
−−
3 −−
−−
0.099
1.6
# Points −− 1094 −− −− −− 1079
# Labs 2 2

Mean 0.478 0.458 −− −− 6.38 6.36
SD
CV
1 0.042
8.7
0.049
10.6
2 −−
−−
−−
−−
3 0.162
2.5
0.107
1.7
# Points 82 1827 −− −− 79 1757
# Labs 2 2 2 2

Mean 0.600 0.600 3.09 3.23 −− −−
SD
CV
1 0.000
0.0
0.000
0.0
2 0.060
1.9
0.102
3.1
3 −−
−−
−−
−−
# Points 22 22 22 124 −− −−
# Labs 1 1 1 2

Mean −− 0.555 −− −− −− 7.19
SD
CV
1 −−
−−
0.014
2.5
2 −−
−−
−−
−−
3 −−
−−
0.162
2.3
# Points −− 1135 −− −− −− 1139
# Labs 3 3

Mean 0.556 0.545 2.99 3.01 7.41 7.41
SD
CV
1 0.053
9.6
0.050
9.2
2 0.089
3.0
0.097
3.2
3 0.223
3.0
0.228
3.1
# Points 1789 102K 403 18421 1575 92827
# Labs 56 256 14 65 48 226

Mean 0.558 0.548 2.89 2.93 7.14 7.14
SD
CV
1 0.042
7.6
0.045
8.3
2 0.117
4.1
0.097
3.3
3 0.223
3.1
0.222
3.1
# Points 3262 244K 954 76090 2676 221K
# Labs 91 476 30 144 76 448
Bilirubin, Total/TBIL Jendrassik Grof mg/dL

Mean −− 0.605 −− 3.24 −− 8.41
SD
CV
1 −−
−−
0.032
5.3
2 −−
−−
0.136
4.2
3 −−
−−
0.403
4.8
# Points −− 454 −− 458 −− 467
# Labs 3 3 3
Method Group • Jendrassik Grof

Mean 0.557 0.551 2.92 2.96 7.23 7.23
SD
CV
1 0.051
9.1
0.057
10.4
2 0.119
4.1
0.120
4.1
3 0.283
3.9
0.275
3.8
# Points 5240 361K 1390 99761 4442 329K
# Labs 153 779 46 229 129 719
Bilirubin, Total/TBIL Sulphanilic acid, DMSO mg/dL

Mean −− 0.588 −− 2.87 −− 7.10
SD
CV
1 −−
−−
0.048
8.2
2 −−
−−
0.137
4.8
3 −−
−−
0.324
4.6
# Points −− 244 −− 244 −− 244
# Labs 1 1 1
RANDOX RX daytona
Mean 0.685 0.578 4.55 3.90 7.10 7.10
SD
CV
1 0.143
20.8
0.142
24.6
2 0.206
4.5
0.736
18.9
3 0.000
0.0
0.000
0.0
# Points 20 90 16 93 1 1
# Labs 1 1 1 1 1 1
RANDOX RX imola
Mean 0.722 0.727 3.11 3.12 −− −−
SD
CV
1 0.016
2.2
0.015
2.1
2 0.029
0.9
0.024
0.8
3 −−
−−
−−
−−
# Points 26 225 24 194 −− −−
# Labs 1 1 1 1

Mean 0.462 0.478 2.56 2.64 6.53 6.62
SD
CV
1 0.020
4.3
0.019
3.9
2 0.081
3.2
0.089
3.4
3 0.173
2.6
0.191
2.9
# Points 48 442 52 447 52 449
# Labs 1 1 1 1 1 1

Mean −− 0.534 −− −− −− 7.47
SD
CV
1 −−
−−
0.034
6.3
2 −−
−−
−−
−−
3 −−
−−
0.197
2.6
# Points −− 987 −− −− −− 1020
# Labs 2 2
Method Group • Sulphanilic acid, DMSO

Mean 0.581 0.552 3.05 2.91 6.54 7.19
SD
CV
1 0.140
24.1
0.083
15.1
2 0.737
24.2
0.443
15.2
3 0.188
2.9
0.424
5.9
# Points 94 1988 92 978 53 1714
# Labs 3 6 3 4 2 5
Bilirubin, Total/TBIL Vanadate Oxidation mg/dL

Mean −− −− −− 2.94 −− 7.08
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.054
1.8
3 −−
−−
0.199
2.8
# Points −− −− −− 209 −− 211
# Labs 2 2

Mean 0.531 0.531 2.81 2.78 6.99 6.83
SD
CV
1 0.007
1.3
0.010
1.8
2 0.018
0.6
0.038
1.4
3 0.050
0.7
0.079
1.2
# Points 15 399 15 428 15 440
# Labs 1 1 1 1 1 1

Mean 0.557 0.561 2.88 2.88 7.15 7.18
SD
CV
1 0.008
1.3
0.010
1.9
2 0.026
0.9
0.060
2.1
3 0.064
0.9
0.119
1.7
# Points 118 2317 118 2121 118 2318
# Labs 3 4 3 4 3 4

Mean −− −− −− 3.12 −− 7.86
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.074
2.4
3 −−
−−
0.161
2.1
# Points −− −− −− 584 −− 578
# Labs 2 2

Mean −− 0.593 −− 2.97 −− 7.64
SD
CV
1 −−
−−
0.014
2.4
2 −−
−−
0.241
8.1
3 −−
−−
0.135
1.8
# Points −− 1354 −− 1783 −− 1548
# Labs 2 4 3

Mean −− 0.606 −− 2.98 −− 7.61
SD
CV
1 −−
−−
0.024
4.0
2 −−
−−
0.108
3.6
3 −−
−−
0.241
3.2
# Points −− 218 −− 218 −− 217
# Labs 1 1 1

Mean 0.553 0.602 3.01 3.19 7.95 8.18
SD
CV
1 0.022
4.0
0.034
5.7
2 0.102
3.4
0.170
5.3
3 0.231
2.9
0.375
4.6
# Points 60 662 60 674 60 673
# Labs 2 2 2 2 2 2

Mean −− 0.640 −− 2.83 −− 8.13
SD
CV
1 −−
−−
0.014
2.2
2 −−
−−
0.051
1.8
3 −−
−−
0.082
1.0
# Points −− 406 −− 744 −− 406
# Labs 1 2 1

Mean −− −− 3.07 3.20 7.62 8.07
SD
CV
1 −−
−−
−−
−−
2 0.069
2.3
0.101
3.2
3 0.153
2.0
0.250
3.1
# Points −− −− 5 376 4 377
# Labs 1 1 1 1

Mean −− −− −− 3.05 −− 7.66
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.054
1.8
3 −−
−−
0.166
2.2
# Points −− −− −− 169 −− 169
# Labs 1 1
Dirui CS Series
Mean −− 0.618 −− 3.07 −− 7.85
SD
CV
1 −−
−−
0.046
7.4
2 −−
−−
0.160
5.2
3 −−
−−
0.409
5.2
# Points −− 893 −− 882 −− 887
# Labs 2 2 2

Mean −− −− 3.17 3.17 7.80 7.87
SD
CV
1 −−
−−
−−
−−
2 0.041
1.3
0.122
3.8
3 0.149
1.9
0.451
5.7
# Points −− −− 12 105 10 105
# Labs 2 2 2 2

Mean −− 0.578 −− 3.09 −− 7.28
SD
CV
1 −−
−−
0.045
7.7
2 −−
−−
0.137
4.4
3 −−
−−
0.475
6.5
# Points −− 4657 −− 2886 −− 4276
# Labs 12 7 12

Mean −− −− −− 2.66 −− 7.04
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.238
9.0
3 −−
−−
0.621
8.8
# Points −− −− −− 106 −− 105
# Labs 1 1

Mean −− 0.533 −− −− −− 7.16
SD
CV
1 −−
−−
0.018
3.3
2 −−
−−
−−
−−
3 −−
−−
0.182
2.5
# Points −− 88 −− −− −− 90
# Labs 1 1

Mean −− 0.547 −− −− −− 7.13
SD
CV
1 −−
−−
0.024
4.4
2 −−
−−
−−
−−
3 −−
−−
0.278
3.9
# Points −− 395 −− −− −− 392
# Labs 2 2
Mindray BS Series
Mean 0.458 0.489 2.43 2.69 6.50 6.91
SD
CV
1 0.029
6.3
0.031
6.4
2 0.101
4.1
0.147
5.5
3 0.210
3.2
0.340
4.9
# Points 21 243 21 464 21 452
# Labs 1 2 1 2 1 2

Mean −− −− −− 3.14 −− 7.88
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.077
2.5
3 −−
−−
0.204
2.6
# Points −− −− −− 274 −− 276
# Labs 2 2

Mean −− −− 2.76 2.75 7.56 7.63
SD
CV
1 −−
−−
−−
−−
2 0.084
3.0
0.098
3.5
3 0.173
2.3
0.188
2.5
# Points −− −− 41 272 92 315
# Labs 1 1 1 1

Mean −− 0.596 −− 3.20 −− −−
SD
CV
1 −−
−−
0.027
4.5
2 −−
−−
0.105
3.3
3 −−
−−
−−
−−
# Points −− 101 −− 93 −− −−
# Labs 1 1

Mean −− 0.576 −− 2.97 −− 7.41
SD
CV
1 −−
−−
0.011
1.9
2 −−
−−
0.040
1.3
3 −−
−−
0.095
1.3
# Points −− 455 −− 629 −− 628
# Labs 2 2 2

Mean −− 0.594 −− 3.08 −− 7.64
SD
CV
1 −−
−−
0.020
3.3
2 −−
−−
0.078
2.5
3 −−
−−
0.186
2.4
# Points −− 272 −− 278 −− 274
# Labs 1 3 1
Roche Hitachi/MODULAR • Wako

Mean −− 0.516 −− −− −− 6.90
SD
CV
1 −−
−−
0.042
8.1
2 −−
−−
−−
−−
3 −−
−−
0.229
3.3
# Points −− 280 −− −− −− 280
# Labs 1 1

Mean 0.609 0.608 3.17 3.17 7.71 7.96
SD
CV
1 0.026
4.2
0.020
3.3
2 0.120
3.8
0.102
3.2
3 0.154
2.0
0.215
2.7
# Points 125 16695 91 13276 117 16768
# Labs 4 38 3 33 4 36

Mean 0.580 0.609 3.07 3.14 7.82 7.99
SD
CV
1 0.041
7.0
0.026
4.3
2 0.098
3.2
0.142
4.5
3 0.296
3.8
0.265
3.3
# Points 602 32450 474 18055 228 23196
# Labs 17 97 15 68 9 76

Mean −− 0.613 −− −− −− 8.09
SD
CV
1 −−
−−
0.012
2.0
2 −−
−−
−−
−−
3 −−
−−
0.117
1.4
# Points −− 86 −− −− −− 86
# Labs 1 1
Toshiba−TBA
Mean −− −− −− −− −− 8.15
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
0.245
3.0
# Points −− −− −− −− −− 84
# Labs 1
Toshiba−TBA • Wako
Mean 0.570 0.552 −− −− 6.75 6.97
SD
CV
1 0.010
1.8
0.014
2.6
2 −−
−−
−−
−−
3 0.000
0.0
0.223
3.2
# Points 2 362 −− −− 1 360
# Labs 1 1 1 1
Method Group • Vanadate Oxidation

Mean 0.576 0.602 3.02 3.10 7.60 7.83
SD
CV
1 0.042
7.3
0.032
5.3
2 0.169
5.6
0.164
5.3
3 0.399
5.3
0.406
5.2
# Points 943 62333 837 44520 666 55406
# Labs 29 172 29 143 25 161
C3 (Complement) Immunonephelometric, end point mg/dL

Mean −− −− −− −− 148.3 147.8
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 3.78
2.5
5.22
3.5
# Points −− −− −− −− 85 802
# Labs 2 2

Mean −− −− −− −− 148.3 147.8
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 3.78
2.5
5.22
3.5
# Points −− −− −− −− 85 802
# Labs 2 2
C3 (Complement) Immunonephelometric, fixed time, kinetic mg/dL

Mean 96.58 91.00 135.9 129.9 174.4 163.8
SD
CV
1 2.60
2.7
3.24
3.6
2 4.98
3.7
4.63
3.6
3 5.27
3.0
6.20
3.8
# Points 34 1531 35 691 33 1526
# Labs 1 12 1 3 1 10

Mean 96.58 91.00 135.9 129.9 174.4 163.8
SD
CV
1 2.60
2.7
3.24
3.6
2
4.98
3.7
4.63
3.6
3 5.27
3.0
6.20
3.8
# Points 34 1531 35 691 33 1526
# Labs 1 12 1 3 1 10
C3 (Complement) Immunoturbidimetric mg/dL

Mean 90.33 89.98 129.1 130.0 −− 160.3
SD
CV
1 1.05
1.2
2.56
2.8
2 0.990
0.8
3.25
2.5
3 −−
−−
3.73
2.3
# Points 15 382 15 95 −− 319
# Labs 1 5 1 4 4

Mean −− 87.84 −− 124.0 −− 153.8
SD
CV
1 −−
−−
19.75
22.5
2 −−
−−
27.38
22.1
3 −−
−−
34.21
22.2
# Points −− 166 −− 172 −− 170
# Labs 3 3 3

Mean 91.42 93.12 131.1 132.4 166.7 167.5
SD
CV
1 1.81
2.0
3.31
3.6
2 2.03
1.6
4.49
3.4
3 2.62
1.6
5.65
3.4
# Points 31 2560 31 1760 31 2823
# Labs 1 7 1 4 1 8
Roche cobas c 303/503 • Roche C3C−2, REF 08105537

Mean −− 102.0 −− −− −− 175.2
SD
CV
1 −−
−−
4.30
4.2
2 −−
−−
−−
−−
3 −−
−−
6.00
3.4
# Points −− 10 −− −− −− 12
# Labs 1 1

Mean 84.02 78.30 116.0 113.3 149.0 141.0
SD
CV
1 4.18
5.0
2.92
3.7
2 2.77
2.4
2.64
2.3
3 4.87
3.3
5.04
3.6
# Points 33 884 6 183 31 878
# Labs 4 6 3 4 2 5

Mean −− −− 117.7 118.2 −− −−
SD
CV
1 −−
−−
−−
−−
2 5.35
4.6
5.13
4.3
3 −−
−−
−−
−−
# Points −− −− 14 18 −− −−
# Labs 1 1

Mean −− 93.92 −− 129.6 −− 158.5
SD
CV
1 −−
−−
2.48
2.6
2 −−
−−
3.80
2.9
3 −−
−−
3.75
2.4
# Points −− 131 −− 154 −− 159
# Labs 1 1 1

Mean 88.12 89.49 126.4 129.9 157.9 160.8
SD
CV
1 4.58
5.2
7.82
8.7
2 6.85
5.4
10.01
7.7
3 9.73
6.2
13.53
8.4
# Points 79 4133 66 2382 62 4361
# Labs 6 23 6 17 3 22
C4 (Complement) Immunonephelometric, end point mg/dL

Mean −− −− −− −− 26.49 27.61
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 1.33
5.0
2.10
7.6
# Points −− −− −− −− 86 791
# Labs 2 2

Mean −− −− −− −− 26.49 27.61
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 1.33
5.0
2.10
7.6
# Points −− −− −− −− 86 791
# Labs 2 2
C4 (Complement) Immunonephelometric, fixed time, kinetic mg/dL

Mean 18.77 18.29 24.50 24.61 30.96 31.02
SD
CV
1 0.530
2.8
0.792
4.3
2 0.460
1.9
0.822
3.3
3 0.960
3.1
1.32
4.2
# Points 31 1514 31 688 31 1417
# Labs 1 11 1 3 1 8

Mean 18.77 18.29 24.50 24.61 30.96 31.02
SD
CV
1 0.530
2.8
0.792
4.3
2
0.460
1.9
0.822
3.3
3 0.960
3.1
1.32
4.2
# Points 31 1514 31 688 31 1417
# Labs 1 11 1 3 1 8

Mean 17.59 16.22 25.12 24.34 −− 30.00
SD
CV
1 0.247
1.4
0.844
5.2
2 0.246
1.0
0.812
3.3
3 −−
−−
0.915
3.1
# Points 15 343 15 101 −− 287
# Labs 1 4 1 4 3
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c C4, REF 09P57

Mean −− 17.15 −− −− −− 33.73
SD
CV
1 −−
−−
0.876
5.1
2 −−
−−
−−
−−
3 −−
−−
2.37
7.0
# Points −− 105 −− −− −− 102
# Labs 1 1

Mean −− 18.27 −− 25.20 −− 31.88
SD
CV
1 −−
−−
4.15
22.7
2 −−
−−
5.57
22.1
3 −−
−−
7.19
22.6
# Points −− 167 −− 175 −− 167
# Labs 3 3 3

Mean 15.13 14.88 21.61 21.30 28.26 28.02
SD
CV
1 0.670
4.4
0.642
4.3
2 0.955
4.4
0.717
3.4
3 1.12
4.0
1.02
3.6
# Points 31 2528 31 1726 31 2840
# Labs 1 7 1 4 1 8
Roche cobas c 303/503 • Roche C4−2, REF 08105545

Mean −− 1697 −− −− −− 2902
SD
CV
1 −−
−−
18.89
1.1
2 −−
−−
−−
−−
3 −−
−−
29.94
1.0
# Points −− 10 −− −− −− 11
# Labs 1 1

Mean 15.45 14.91 21.66 21.22 27.20 27.27
SD
CV
1 0.527
3.4
0.516
3.5
2 0.451
2.1
0.658
3.1
3 0.697
2.6
0.621
2.3
# Points 35 875 8 175 33 863
# Labs 4 6 3 4 2 5

Mean −− −− 21.07 21.41 −− −−
SD
CV
1 −−
−−
−−
−−
2 1.68
8.0
1.57
7.4
3 −−
−−
−−
−−
# Points −− −− 10 14 −− −−
# Labs 1 1

Mean −− 17.72 −− 24.20 −− 30.65
SD
CV
1 −−
−−
0.632
3.6
2 −−
−−
0.798
3.3
3 −−
−−
0.928
3.0
# Points −− 155 −− 150 −− 159
# Labs 1 1 1

Mean 15.72 15.30 22.36 21.90 27.71 28.38
SD
CV
1 1.06
6.7
1.40
9.1
2 1.81
8.1
2.13
9.7
3 1.06
3.8
2.17
7.6
# Points 81 4183 64 2341 64 4429
# Labs 6 23 6 17 3 22
Calcium AAS (Atomic Absorption Spectroscopy) mg/dL

Mean −− −− −− 9.97 −− 12.97
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.118
1.2
3 −−
−−
0.158
1.2
# Points −− −− −− 590 −− 593
# Labs 3 3

Mean −− 6.12 −− −− −− 12.56
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− 1 −− −− −− 1
# Labs 1 1
Method Group • AAS (Atomic Absorption Spectroscopy)

Mean −− 6.12 −− 9.97 −− 12.97
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
0.118
1.2
3 −−
−−
0.159
1.2
# Points −− 1 −− 590 −− 594
# Labs 1 3 4
Calcium Arsenazo III mg/dL

Mean 6.84 6.70 10.28 10.18 −− 13.01
SD
CV
1 0.000
0.0
0.201
3.0
2 0.000
0.0
0.159
1.6
3 −−
−−
0.391
3.0
# Points 1 103 1 22 −− 78
# Labs 1 2 1 1 2

Mean 6.24 6.29 9.79 9.90 12.90 13.03
SD
CV
1 0.126
2.0
0.144
2.3
2 0.215
2.2
0.209
2.1
3 0.246
1.9
0.269
2.1
# Points 2132 76216 1250 39386 1281 72550
# Labs 73 244 58 162 42 198

Abbott ARCHITECT/Alinity (c, i, ci models) • 1drop 1copy COVID−19 qPCR
Mean −− 6.44 −− 10.04 −− −−
SD
CV
1 −−
−−
0.000
0.0
2
−−
−−
0.000
0.0
3 −−
−−
−−
−−
# Points −− 1 −− 1 −− −−
# Labs 1 1
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH Calcium REF 3L79

Mean 6.22 6.18 9.86 9.77 −− −−
SD
CV
1 0.055
0.9
0.097
1.6
2
0.051
0.5
0.148
1.5
3 −−
−−
−−
−−
# Points 13 169 13 169 −− −−
# Labs 1 1 1 1
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c Calcium, REF 07P57

Mean −− 6.29 −− 9.93 −− 13.01
SD
CV
1 −−
−−
0.152
2.4
2−−
−−
0.102
1.0
3 −−
−−
0.255
2.0
# Points −− 324 −− 91 −− 234
# Labs 2 1 1

Mean 6.20 6.27 9.72 9.80 12.84 13.00
SD
CV
1 0.062
1.0
0.080
1.3
0.080
0.8
2 0.221
2.3
3 0.108
0.8
0.182
1.4
# Points 88 1339 86 1795 87 1405
# Labs 2 2 2 4 2 3

Mean 6.12 6.19 9.91 9.96 13.06 13.05
SD
CV
1 0.178
2.9
0.160
2.6
2 0.243
2.4
0.225
2.3
3 0.307
2.4
0.279
2.1
# Points 2270 111K 1823 84319 1353 113K
# Labs 77 316 60 240 45 296

Mean −− 6.27 −− 9.94 −− 13.04
SD
CV
1 −−
−−
0.120
1.9
2 −−
−−
0.215
2.2
3 −−
−−
0.225
1.7
# Points −− 719 −− 992 −− 719
# Labs 6 8 6
Beckman Coulter AU Series • Beckman Coulter Urine Cal, DR0090

Mean −− −− 9.82 9.82 −− −−
SD
CV
1 −−
−−
−−
−−
0.159
1.6
2 0.159
1.6
3 −−
−−
−−
−−
# Points −− −− 31 31 −− −−
# Labs 1 1

Mean −− −− −− 9.55 −− 12.47
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.223
2.3
3 −−
−−
0.254
2.0
# Points −− −− −− 1161 −− 1156
# Labs 3 3

Mean −− 5.88 −− 9.37 −− 12.23
SD
CV
1 −−
−−
0.207
3.5
2 −−
−−
0.306
3.3
3 −−
−−
0.410
3.4
# Points −− 274 −− 274 −− 274
# Labs 1 1 1

Mean 6.10 6.10 9.70 9.71 12.50 12.53
SD
CV
1 0.103
1.7
0.099
1.6
2 0.153
1.6
0.151
1.6
3 0.175
1.4
0.193
1.5
# Points 63 672 63 667 63 672
# Labs 2 2 2 2 2 2

Mean −− −− 10.12 9.84 12.92 12.71
SD
CV
1 −−
−−
−−
−−
2 0.080
0.8
0.266
2.7
3 0.040
0.3
0.314
2.5
# Points −− −− 5 718 4 719
# Labs 1 2 1 2

Mean −− 5.93 −− 9.54 −− 12.50
SD
CV
1 −−
−−
0.118
2.0
2 −−
−−
0.151
1.6
3 −−
−−
0.161
1.3
# Points −− 43 −− 43 −− 43
# Labs 1 1 1

Mean −− −− 9.73 9.77 11.29 11.75
SD
CV
1 −−
−−
−−
−−
2 0.249
2.6
0.315
3.2
3 0.785
7.0
1.01
8.6
# Points −− −− 43 222 40 221
# Labs 3 3 3 3

Mean 6.33 6.27 10.08 9.99 12.64 12.92
SD
CV
1 0.374
5.9
0.344
5.5
2 0.389
3.9
0.420
4.2
3 0.270
2.1
0.391
3.0
# Points 54 681 38 531 5 44
# Labs 3 4 3 4 1 2
ERBA XL−640
Mean −− 6.21 −− 9.84 −− −−
SD
CV
1 −−
−−
0.163
2.6
2 −−
−−
0.184
1.9
3 −−
−−
−−
−−
# Points −− 58 −− 58 −− −−
# Labs 1 1

Mean −− 5.98 −− −− −− −−
SD
CV
1 −−
−−
0.109
1.8
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 24 −− −− −− −−
# Labs 1

Mean −− 6.11 −− 9.86 −− 12.97
SD
CV
1 −−
−−
0.186
3.0
2 −−
−−
0.233
2.4
3 −−
−−
0.362
2.8
# Points −− 798 −− 799 −− 802
# Labs 3 3 3
Hitachi Chemistry Series • Kainos

Mean −− 6.30 −− −− −− −−
SD
CV
1 −−
−−
0.070
1.1
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 65 −− −− −− −−
# Labs 1

Mean −− 6.28 −− −− −− 13.04
SD
CV
1 −−
−−
0.266
4.2
2 −−
−−
−−
−−
3 −−
−−
0.252
1.9
# Points −− 91 −− −− −− 93
# Labs 1 1

Mean −− 6.23 −− 10.09 −− 13.38
SD
CV
1 −−
−−
0.380
6.1
2 −−
−−
0.677
6.7
3 −−
−−
0.821
6.1
# Points −− 35 −− 35 −− 35
# Labs 1 1 1

Mindray BS Series
Mean 6.08 6.29 9.76 10.21 12.64 13.13
SD
CV
1 0.080
1.3
0.212
3.4
2 0.120
1.2
0.244
2.4
3 0.120
0.9
0.342
2.6
# Points 21 253 21 472 21 496
# Labs 1 2 1 2 1 2

Mean −− −− −− 9.97 −− 12.79
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.135
1.4
3 −−
−−
0.138
1.1
# Points −− −− −− 148 −− 148
# Labs 1 1

Mean −− −− −− 9.98 −− 12.73
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.332
3.3
3 −−
−−
0.425
3.3
# Points −− −− −− 282 −− 284
# Labs 2 2
RANDOX RX daytona
Mean −− 6.08 10.84 9.85 13.97 13.97
SD
CV
1 −−
−−
0.468
7.7
2 0.748
6.9
0.950
9.6
3 0.000
0.0
0.000
0.0
# Points −− 43 16 164 1 1
# Labs 1 1 1 1 1
RANDOX RX imola
Mean 6.72 6.74 10.30 10.20 −− −−
SD
CV
1 0.109
1.6
0.125
1.9
2 0.082
0.8
0.153
1.5
3 −−
−−
−−
−−
# Points 25 225 23 195 −− −−
# Labs 1 1 1 1

Mean −− −− −− 9.99 −− 13.03
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.173
1.7
3 −−
−−
0.203
1.6
# Points −− −− −− 1514 −− 1445
# Labs 4 4

Mean 6.36 6.31 10.20 10.12 13.20 13.16
SD
CV
1 0.160
2.5
0.120
1.9
2 0.160
1.6
0.140
1.4
3 0.200
1.5
0.177
1.3
# Points 49 442 49 443 47 439
# Labs 1 1 1 1 1 1

Mean −− 6.18 −− 9.94 −− 12.83
SD
CV
1 −−
−−
0.110
1.8
2 −−
−−
0.127
1.3
3 −−
−−
0.151
1.2
# Points −− 628 −− 629 −− 628
# Labs 2 2 2
Mean −− −− −− 10.51 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.121
1.2
3 −−
−−
−−
−−
# Points −− −− −− 31 −− −−
# Labs 1

Mean −− −− −− 10.12 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.185
1.8
3 −−
−−
−−
−−
# Points −− −− −− 24 −− −−
# Labs 1

Mean 6.21 6.23 9.81 9.81 12.49 12.77
SD
CV
1 0.122
2.0
0.183
2.9
2 0.225
2.3
0.269
2.7
3 0.220
1.8
0.290
2.3
# Points 88 15000 85 11647 119 14927
# Labs 3 30 3 26 4 31
Siemens ADVIA Chemistry Systems • Abbott ARCH Calcium REF 3L79

Mean −− 6.31 −− 9.89 −− 12.77
SD
CV
1 −−
−−
0.284
4.5
−−
−−
2 0.252
2.5
3 −−
−−
0.334
2.6
# Points −− 491 −− 487 −− 491
# Labs 2 2 2

Mean 6.32 6.36 9.92 10.00 13.02 12.96
SD
CV
1 0.129
2.0
0.173
2.7
2 0.150
1.5
0.225
2.2
3 0.238
1.8
0.322
2.5
# Points 482 18003 358 9533 138 14685
# Labs 14 67 10 47 6 49

Mean −− −− 9.93 9.92 −− −−
SD
CV
1 −−
−−
−−
−−
2 0.153
1.5
0.139
1.4
3 −−
−−
−−
−−
# Points −− −− 20 28 −− −−
# Labs 1 1

Mean −− 5.64 −− 9.24 −− 12.07
SD
CV
1 −−
−−
0.117
2.1
2 −−
−−
0.189
2.0
3 −−
−−
0.237
2.0
# Points −− 107 −− 107 −− 107
# Labs 1 1 1
Toshiba−TBA
Mean −− −− −− −− −− 13.14
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
0.251
1.9
# Points −− −− −− −− −− 75
# Labs 1

Mean −− 6.07 −− −− −− 12.85
SD
CV
1 −−
−−
0.117
1.9
2 −−
−−
−−
−−
3 −−
−−
0.185
1.4
# Points −− 267 −− −− −− 267
# Labs 1 1
Method Group • Arsenazo III

Mean 6.20 6.24 9.87 9.93 12.93 13.01
SD
CV
1 0.174
2.8
0.171
2.7
2 0.249
2.5
0.238
2.4
3 0.366
2.8
0.298
2.3
# Points 5286 228K 3925 157K 3159 226K
# Labs 179 698 150 533 109 623
Calcium Arsenazo III−VITROS mg/dL

Mean 6.12 5.97 10.38 10.30 12.65 12.55
SD
CV
1 0.198
3.2
0.222
3.7
2 0.941
9.1
0.713
6.9
3 0.255
2.0
0.316
2.5
# Points 32 1920 64 1798 64 2251
# Labs 4 17 4 13 5 15

Mean 6.08 6.09 −− 10.20 12.79 12.84
SD
CV
1 0.077
1.3
0.138
2.3
2 −−
−−
0.270
2.7
3 0.117
0.9
0.355
2.8
# Points 3 1123 −− 358 3 1172
# Labs 1 9 3 1 10

Mean −− 6.00 −− 10.10 −− 12.80
SD
CV
1 −−
−−
0.270
4.5
2 −−
−−
0.186
1.8
3 −−
−−
0.294
2.3
# Points −− 321 −− 161 −− 443
# Labs 5 6 10

Mean −− 6.05 −− 9.90 −− 12.67
SD
CV
1 −−
−−
0.148
2.4
2 −−
−−
0.168
1.7
3 −−
−−
0.261
2.1
# Points −− 929 −− 114 −− 977
# Labs 10 3 9

Mean −− 6.18 −− 10.02 −− 12.74
SD
CV
1 −−
−−
0.143
2.3
2 −−
−−
0.168
1.7
3 −−
−−
0.197
1.5
# Points −− 1245 −− 1117 −− 1300
# Labs 11 6 11

Mean −− 6.14 −− 9.93 −− 12.90
SD
CV
1 −−
−−
0.165
2.7
2 −−
−−
0.058
0.6
3 −−
−−
0.164
1.3
# Points −− 902 −− 3 −− 394
# Labs 10 1 9

Mean −− 6.16 −− 10.14 −− 12.81
SD
CV
1 −−
−−
0.153
2.5
2 −−
−−
0.301
3.0
3 −−
−−
0.244
1.9
# Points −− 5023 −− 1903 −− 4472
# Labs 39 15 37

Mean −− 6.05 −− −− −− 12.90
SD
CV
1 −−
−−
0.101
1.7
2 −−
−−
−−
−−
3 −−
−−
0.160
1.2
# Points −− 104 −− −− −− 104
# Labs 1 1

Mean −− 6.02 −− 9.93 −− 12.67
SD
CV
1 −−
−−
0.120
2.0
2 −−
−−
0.147
1.5
3 −−
−−
0.161
1.3
# Points −− 1773 −− 480 −− 1419
# Labs 20 5 19

Mean −− 6.04 −− 9.89 −− 12.68
SD
CV
1 −−
−−
0.153
2.5
2 −−
−−
0.196
2.0
3 −−
−−
0.271
2.1
# Points −− 2672 −− 1003 −− 2312
# Labs 24 9 23

Mean −− 6.09 −− 10.07 −− 12.80
SD
CV
1 −−
−−
0.152
2.5
2 −−
−−
0.204
2.0
3 −−
−−
0.273
2.1
# Points −− 4989 −− 2497 −− 4866
# Labs 45 20 44

Mean −− 6.06 −− 9.94 −− 12.73
SD
CV
1 −−
−−
0.150
2.5
2 −−
−−
0.201
2.0
3 −−
−−
0.247
1.9
# Points −− 8211 −− 3597 −− 8857
# Labs 64 26 65

Mean 6.27 6.12 −− 9.93 12.90 12.91
SD
CV
1 0.130
2.1
0.150
2.5
2 −−
−−
0.154
1.5
3 0.240
1.9
0.305
2.4
# Points 33 2194 −− 523 32 2177
# Labs 1 13 7 1 13

Mean 5.75 5.93 −− 9.77 12.37 12.57
SD
CV
1 0.040
0.7
0.157
2.6
2 −−
−−
0.159
1.6
3 0.090
0.7
0.230
1.8
# Points 22 3321 −− 1285 22 3202
# Labs 1 17 8 1 17

Mean 6.00 6.02 9.70 9.92 12.55 12.71
SD
CV
1 0.161
2.7
0.143
2.4
2 0.096
1.0
0.232
2.3
3 0.263
2.1
0.267
2.1
# Points 182 3687 61 1154 155 3231
# Labs 7 36 2 12 7 32

Mean 6.21 6.10 10.17 9.96 13.03 12.79
SD
CV
1 0.133
2.1
0.135
2.2
2 0.292
2.9
0.408
4.1
3 0.254
1.9
0.216
1.7
# Points 81 793 68 166 34 647
# Labs 5 12 5 6 4 10

Mean −− 6.07 −− 10.06 −− 12.74
SD
CV
1 −−
−−
0.152
2.5
2 −−
−−
0.223
2.2
3 −−
−−
0.281
2.2
# Points −− 4550 −− 1133 −− 4273
# Labs 47 16 45

Mean −− 6.08 −− 10.02 −− 12.77
SD
CV
1 −−
−−
0.199
3.3
2 −−
−−
0.233
2.3
3 −−
−−
0.312
2.4
# Points −− 852 −− 852 −− 723
# Labs 4 4 3

Mean −− 6.04 −− 9.89 −− 12.65
SD
CV
1 −−
−−
0.122
2.0
2 −−
−−
0.238
2.4
3 −−
−−
0.266
2.1
# Points −− 907 −− 548 −− 905
# Labs 7 4 7

Mean −− 6.06 −− 10.00 −− 12.72
SD
CV
1 −−
−−
0.145
2.4
2 −−
−−
0.149
1.5
3 −−
−−
0.212
1.7
# Points −− 1808 −− 720 −− 1736
# Labs 16 5 14

Mean −− 6.01 −− 9.87 −− 12.55
SD
CV
1 −−
−−
0.129
2.2
2 −−
−−
0.152
1.5
3 −−
−−
0.234
1.9
# Points −− 2666 −− 606 −− 2522
# Labs 26 7 26

Mean 5.94 5.99 −− 9.89 12.56 12.64
SD
CV
1 0.070
1.2
0.148
2.5
2 −−
−−
0.173
1.7
3 0.097
0.8
0.184
1.5
# Points 20 1273 −− 420 20 1022
# Labs 1 11 3 1 8

Mean −− 6.12 −− 9.96 −− 12.64
SD
CV
1 −−
−−
0.169
2.8
2 −−
−−
0.247
2.5
3 −−
−−
0.314
2.5
# Points −− 1648 −− 555 −− 1878
# Labs 19 9 24

Mean 6.03 6.07 9.88 9.99 12.89 12.71
SD
CV
1 0.070
1.2
0.135
2.2
2 0.169
1.7
0.225
2.3
3 0.252
2.0
0.256
2.0
# Points 18 3789 23 1408 22 3637
# Labs 1 27 1 6 1 24

Mean 5.50 5.97 −− −− 12.78 13.13
SD
CV
1 0.176
3.2
0.248
4.1
2 −−
−−
−−
−−
3 0.243
1.9
0.404
3.1
# Points 22 291 −− −− 22 328
# Labs 1 3 1 3

Mean −− 6.05 −− 10.06 −− 12.76
SD
CV
1 −−
−−
0.149
2.5
2 −−
−−
0.233
2.3
3 −−
−−
0.260
2.0
# Points −− 1799 −− 674 −− 1678
# Labs 19 8 16

Mean −− 6.07 −− 10.13 −− 12.65
SD
CV
1 −−
−−
0.141
2.3
2 −−
−−
0.239
2.4
3 −−
−−
0.309
2.4
# Points −− 1848 −− 473 −− 1887
# Labs 22 5 21

Mean 6.00 6.07 −− 9.96 −− 12.76
SD
CV
1 0.166
2.8
0.156
2.6
2 −−
−−
0.200
2.0
3 −−
−−
0.269
2.1
# Points 4 2432 −− 812 −− 2178
# Labs 1 29 11 21

Mean 5.84 5.89 −− −− 12.19 12.24
SD
CV
1 0.070
1.2
0.095
1.6
2 −−
−−
−−
−−
3 0.148
1.2
0.135
1.1
# Points 31 71 −− −− 31 71
# Labs 1 1 1 1

Mean −− 6.11 −− −− −− 12.97
SD
CV
1 −−
−−
0.112
1.8
2 −−
−−
−−
−−
3 −−
−−
0.164
1.3
# Points −− 375 −− −− −− 372
# Labs 3 4

Mean −− 6.00 −− 9.70 −− 12.56
SD
CV
1 −−
−−
0.133
2.2
2 −−
−−
0.090
0.9
3 −−
−−
0.256
2.0
# Points −− 291 −− 54 −− 290
# Labs 2 1 2

Mean 6.11 6.09 10.01 10.07 12.83 12.70
SD
CV
1 0.086
1.4
0.134
2.2
2 0.113
1.1
0.153
1.5
3 0.116
0.9
0.250
2.0
# Points 78 2589 72 1506 36 2231
# Labs 4 31 3 14 2 26

Mean 5.96 6.08 9.87 10.05 12.56 12.79
SD
CV
1 0.140
2.4
0.149
2.4
2 0.286
2.9
0.238
2.4
3 0.337
2.7
0.303
2.4
# Points 156 2798 81 1644 140 2398
# Labs 7 28 4 21 5 19

Mean 6.02 6.02 9.89 9.91 12.60 12.64
SD
CV
1 0.105
1.7
0.118
2.0
2 0.142
1.4
0.188
1.9
3 0.171
1.4
0.247
2.0
# Points 87 1195 67 435 67 1029
# Labs 7 17 5 6 4 14

Mean −− 5.90 −− 10.10 −− 12.91
SD
CV
1 −−
−−
0.251
4.3
2 −−
−−
0.586
5.8
3 −−
−−
0.174
1.3
# Points −− 210 −− 137 −− 215
# Labs 3 1 3

Mean 6.05 6.05 10.01 9.96 12.66 12.66
SD
CV
1 0.118
1.9
0.121
2.0
2 0.138
1.4
0.148
1.5
3 0.149
1.2
0.165
1.3
# Points 52 823 52 822 52 819
# Labs 2 7 2 8 2 7

Mean 5.82 6.10 −− −− 12.82 12.89
SD
CV
1 0.159
2.7
0.191
3.1
2 −−
−−
−−
−−
3 0.200
1.6
0.228
1.8
# Points 25 764 −− −− 26 750
# Labs 1 9 1 9

Mean 6.13 6.04 9.99 9.95 12.76 12.78
SD
CV
1 0.059
1.0
0.183
3.0
2 0.093
0.9
0.087
0.9
3 0.141
1.1
0.193
1.5
# Points 77 431 46 123 77 397
# Labs 3 6 2 2 3 6

Mean −− 5.99 −− 9.70 −− 13.10
SD
CV
1 −−
−−
0.142
2.4
2 −−
−−
0.000
0.0
3 −−
−−
0.239
1.8
# Points −− 134 −− 1 −− 134
# Labs 5 1 5

Mean 6.19 6.07 10.22 10.10 13.14 12.87
SD
CV
1 0.140
2.3
0.153
2.5
2 0.265
2.6
0.183
1.8
3 0.333
2.5
0.234
1.8
# Points 176 1433 110 636 127 1329
# Labs 8 15 4 6 5 12

Mean 6.09 6.00 10.07 9.82 12.81 12.64
SD
CV
1 0.096
1.6
0.154
2.6
2 0.150
1.5
0.156
1.6
3 0.186
1.5
0.227
1.8
# Points 297 2596 79 1694 251 2501
# Labs 13 20 6 10 11 18

Mean −− 5.96 −− 9.93 −− 12.68
SD
CV
1 −−
−−
0.100
1.7
2 −−
−−
0.179
1.8
3 −−
−−
0.222
1.8
# Points −− 547 −− 799 −− 1260
# Labs 3 3 5

Mean −− 6.07 −− 10.16 −− 12.73
SD
CV
1 −−
−−
0.121
2.0
2 −−
−−
0.116
1.1
3 −−
−−
0.364
2.9
# Points −− 699 −− 58 −− 436
# Labs 4 1 4

Mean 6.08 6.09 10.08 9.97 12.80 12.81
SD
CV
1 0.157
2.6
0.174
2.9
2 0.204
2.0
0.171
1.7
3 0.169
1.3
0.243
1.9
# Points 169 1346 82 615 118 852
# Labs 6 15 3 6 4 13

Mean −− 5.93 −− −− −− 12.27
SD
CV
1 −−
−−
0.088
1.5
2 −−
−−
−−
−−
3 −−
−−
0.146
1.2
# Points −− 123 −− −− −− 122
# Labs 2 2

Mean −− 6.12 −− −− −− 12.55
SD
CV
1 −−
−−
0.065
1.1
2 −−
−−
−−
−−
3 −−
−−
0.071
0.6
# Points −− 41 −− −− −− 42
# Labs 1 1
Method Group • Arsenazo III−VITROS

Mean 6.06 6.06 10.04 10.00 12.74 12.72
SD
CV
1 0.174
2.9
0.160
2.6
2 0.369
3.7
0.288
2.9
3 0.307
2.4
0.276
2.2
# Points 1565 78510 805 32596 1299 75391
# Labs 75 734 41 301 60 687
Calcium BAPTA mg/dL

Mean −− 6.13 −− 9.73 −− 12.61
SD
CV
1 −−
−−
0.109
1.8
2 −−
−−
0.158
1.6
3 −−
−−
0.188
1.5
# Points −− 124 −− 124 −− 124
# Labs 1 1 1

Mean 6.32 6.33 10.01 10.07 13.08 13.12
SD
CV
1 0.120
1.9
0.138
2.2
2 0.182
1.8
0.194
1.9
3 0.210
1.6
0.240
1.8
# Points 2916 89250 417 37207 2920 93590
# Labs 50 197 11 106 49 207

Mean 6.27 6.37 10.03 10.15 13.10 13.19
SD
CV
1 0.120
1.9
0.118
1.8
2 0.135
1.3
0.160
1.6
3 0.127
1.0
0.188
1.4
# Points 279 7404 247 6589 137 6433
# Labs 7 21 6 16 5 19
Roche cobas c 303/503 • Roche CA2, REF 08057427

Mean 6.36 6.37 10.17 10.14 13.09 13.13
SD
CV
1 0.116
1.8
0.134
2.1
2 0.131
1.3
0.108
1.1
3 0.187
1.4
0.279
2.1
# Points 364 11137 131 2171 229 11151
# Labs 10 34 3 9 7 31

Mean 6.31 6.28 10.03 10.01 13.04 13.19
SD
CV
1 0.084
1.3
0.128
2.0
2 0.126
1.3
0.166
1.7
3 0.160
1.2
0.203
1.5
# Points 97 1205 98 1597 14 545
# Labs 2 2 2 3 1 2
Calcium BAPTA mg/dL

Mean 6.19 6.18 9.90 9.76 13.02 12.99
SD
CV
1 0.190
3.1
0.168
2.7
2 0.200
2.0
0.219
2.2
3 0.206
1.6
0.285
2.2
# Points 97 3677 37 750 94 3651
# Labs 3 10 1 1 3 10

Mean −− 6.35 −− −− −− 13.31
SD
CV
1 −−
−−
0.179
2.8
2 −−
−−
−−
−−
3 −−
−−
0.305
2.3
# Points −− 123 −− −− −− 122
# Labs 1 1
Method Group • BAPTA

Mean 6.31 6.33 10.04 10.08 13.08 13.12
SD
CV
1 0.124
2.0
0.141
2.2
2 0.170
1.7
0.193
1.9
3 0.205
1.6
0.245
1.9
# Points 3753 113K 930 48438 3394 116K
# Labs 72 266 23 136 65 271
Calcium Chloranilic acid mg/dL

Mean −− 6.33 −− 9.95 −− 13.16
SD
CV
1 −−
−−
0.091
1.4
2 −−
−−
0.069
0.7
3 −−
−−
0.080
0.6
# Points −− 64 −− 60 −− 58
# Labs 2 2 2
Method Group • Chloranilic acid

Mean −− 6.33 −− 9.95 −− 13.16
SD
CV
1 −−
−−
0.091
1.4
2 −−
−−
0.069
0.7
3 −−
−−
0.080
0.6
# Points −− 64 −− 60 −− 58
# Labs 2 2 2
Calcium Chlorophosphonazo III mg/dL

Mean −− 6.19 −− 10.57 −− −−
SD
CV
1 −−
−−
0.183
3.0
2 −−
−−
0.231
2.2
3 −−
−−
−−
−−
# Points −− 47 −− 84 −− −−
# Labs 1 2
Fuji Dri−Chem Series • Fuji Dri−Chem Ca−PIII, REF 9903050

Mean −− 5.34 −− 9.58 −− −−
SD
CV
1 −−
−−
0.126
2.4
2 −−
−−
0.243
2.5
3 −−
−−
−−
−−
# Points −− 16 −− 16 −− −−
# Labs 2 2

Mean 6.24 6.19 10.04 9.98 13.17 13.14
SD
CV
1 0.175
2.8
0.185
3.0
2 0.202
2.0
0.186
1.9
3 0.263
2.0
0.247
1.9
# Points 62 184 62 184 62 184
# Labs 2 2 2 2 2 2
Method Group • Chlorophosphonazo III

Mean 6.24 6.13 10.04 10.13 13.17 13.14
SD
CV
1 0.175
2.8
0.289
4.7
2 0.202
2.0
0.363
3.6
3 0.263
2.0
0.247
1.9
# Points 62 250 62 287 62 184
# Labs 2 5 2 6 2 2
Calcium ISE direct mg/dL

Mean −− 6.47 −− 9.77 −− 13.11
SD
CV
1 −−
−−
0.185
2.9
2 −−
−−
0.379
3.9
3 −−
−−
0.387
3.0
# Points −− 44 −− 6 −− 60
# Labs 1 1 1
Method Group • ISE direct

Mean −− 6.47 −− 10.20 −− 13.20
SD
CV
1 −−
−−
0.185
2.9
2 −−
−−
0.235
2.3
3 −−
−−
0.353
2.7
# Points −− 44 −− 46 −− 100
# Labs 1 2 2
Calcium ISE indirect mg/dL

Mean −− 6.19 −− 9.88 −− 13.00
SD
CV
1 −−
−−
0.131
2.1
2 −−
−−
0.143
1.4
3 −−
−−
0.258
2.0
# Points −− 2417 −− 1483 −− 1663
# Labs 8 3 8

Mean 6.04 6.16 −− 9.74 12.31 12.55
SD
CV
1 0.118
1.9
0.124
2.0
2 −−
−−
0.188
1.9
3 0.219
1.8
0.187
1.5
# Points 80 15465 −− 4304 75 14942
# Labs 2 34 12 2 32

Mean −− −− −− 9.54 −− 12.50
SD
CV
1 −−
−−
−−
−−
2
−−
−−
0.215
2.3
3 −−
−−
0.295
2.4
# Points −− −− −− 105 −− 105
# Labs 1 1
Mindray BS Series
Mean −− 6.21 −− 12.71 −− −−
SD
CV
1 −−
−−
0.091
1.5
2 −−
−−
0.112
0.9
3 −−
−−
−−
−−
# Points −− 224 −− 221 −− −−
# Labs 1 1

Mean −− 6.30 −− 10.02 −− 13.02
SD
CV
1 −−
−−
0.100
1.6
2 −−
−−
0.112
1.1
3 −−
−−
0.146
1.1
# Points −− 225 −− 225 −− 225
# Labs 1 1 1

Mean −− 6.08 −− 9.77 −− 12.64
SD
CV
1 −−
−−
0.094
1.5
2 −−
−−
0.149
1.5
3 −−
−−
0.198
1.6
# Points −− 454 −− 460 −− 481
# Labs 3 3 3

Mean 6.04 6.16 −− 9.88 12.31 12.60
SD
CV
1 0.118
1.9
0.126
2.0
2 −−
−−
0.555
5.6
3 0.219
1.8
0.240
1.9
# Points 80 18784 −− 6693 75 17312
# Labs 2 47 20 2 44
Calcium Methylthymol blue mg/dL

Mean −− 6.04 −− −− −− 12.93
SD
CV
1 −−
−−
0.117
1.9
2 −−
−−
−−
−−
3 −−
−−
0.195
1.5
# Points −− 1598 −− −− −− 1602
# Labs 4 4

Mean −− 6.05 −− −− −− 12.86
SD
CV
1 −−
−−
0.184
3.0
2 −−
−−
−−
−−
3 −−
−−
0.329
2.6
# Points −− 452 −− −− −− 448
# Labs 2 2
Method Group • Methylthymol blue

Mean −− 6.04 −− −− −− 12.91
SD
CV
1 −−
−−
0.138
2.3
2 −−
−−
−−
−−
3 −−
−−
0.233
1.8
# Points −− 2052 −− −− −− 2050
# Labs 8 6
Calcium MethylXylenol Blue (MXB) mg/dL

Mean −− −− −− 9.76 −− 12.84
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.134
1.4
3 −−
−−
0.163
1.3
# Points −− −− −− 207 −− 205
# Labs 1 1
Method Group • MethylXylenol Blue (MXB)

Mean −− −− −− 9.76 −− 12.84
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.134
1.4
3 −−
−−
0.163
1.3
# Points −− −− −− 207 −− 205
# Labs 1 1
Calcium o−cresolphthalein complexone mg/dL

Mean −− 6.02 −− 9.80 −− 12.83
SD
CV
1 −−
−−
0.119
2.0
2 −−
−−
0.133
1.4
3 −−
−−
0.157
1.2
# Points −− 268 −− 268 −− 268
# Labs 1 1 1

Mean −− 6.19 −− 9.94 −− 12.93
SD
CV
1 −−
−−
0.127
2.1
2 −−
−−
0.167
1.7
3 −−
−−
0.313
2.4
# Points −− 4048 −− 2982 −− 4305
# Labs 10 7 13

Mean −− 6.17 −− −− −− 12.95
SD
CV
1 −−
−−
0.174
2.8
2 −−
−−
−−
−−
3 −−
−−
0.256
2.0
# Points −− 222 −− −− −− 202
# Labs 1 1

Mean −− 6.04 −− 9.79 −− 12.84
SD
CV
1 −−
−−
0.211
3.5
2 −−
−−
0.226
2.3
3 −−
−−
0.307
2.4
# Points −− 2017 −− 2064 −− 2047
# Labs 4 4 4

Mean −− 6.17 −− −− −− 13.14
SD
CV
1 −−
−−
0.170
2.8
2 −−
−−
−−
−−
3 −−
−−
0.407
3.1
# Points −− 41 −− −− −− 42
# Labs 1 1

Mean 6.16 6.26 −− 9.92 12.75 12.96
SD
CV
1 0.084
1.4
0.111
1.8
2 −−
−−
0.161
1.6
3 0.141
1.1
0.198
1.5
# Points 23 2462 −− 1609 23 2447
# Labs 1 5 3 1 5

Mean 6.36 6.36 −− 10.11 13.12 13.10
SD
CV
1 0.040
0.6
0.095
1.5
2 −−
−−
0.159
1.6
3 0.040
0.3
0.143
1.1
# Points 23 979 −− 925 23 887
# Labs 1 2 1 1 2

Mean −− 6.31 −− −− −− 13.03
SD
CV
1 −−
−−
0.100
1.6
2 −−
−−
−−
−−
3 −−
−−
0.159
1.2
# Points −− 26 −− −− −− 25
# Labs 1 1

Mean −− 6.30 −− 10.07 −− 13.10
SD
CV
1 −−
−−
0.098
1.6
2 −−
−−
0.109
1.1
3 −−
−−
0.135
1.0
# Points −− 65 −− 65 −− 65
# Labs 1 1 1

Mean 5.49 6.16 9.36 9.72 12.28 12.53
SD
CV
1 0.168
3.1
0.326
5.3
2 0.156
1.7
0.377
3.9
3 0.148
1.2
0.454
3.6
# Points 31 748 31 786 31 786
# Labs 1 3 1 3 1 3
Mean −− 6.23 −− 10.02 −− 13.22
SD
CV
1 −−
−−
0.370
5.9
2 −−
−−
0.349
3.5
3 −−
−−
0.612
4.6
# Points −− 197 −− 198 −− 200
# Labs 1 1 1

Mean 5.97 5.96 9.61 9.78 −− 12.80
SD
CV
1 0.248
4.1
0.151
2.5
2 0.310
3.2
0.210
2.1
3 −−
−−
0.252
2.0
# Points 59 1021 22 920 −− 1143
# Labs 2 8 1 6 6

Mean 5.75 5.95 9.82 9.81 12.93 13.13
SD
CV
1 0.277
4.8
0.202
3.4
2 0.332
3.4
0.241
2.5
3 0.465
3.6
0.300
2.3
# Points 79 15279 118 8414 113 11356
# Labs 4 36 5 24 4 34
Siemens Atellica CH Analyzer • Siemens Atellica CH CA_2, REF 11097644

Mean −− 6.11 −− −− −− 13.10
SD
CV
1 −−
−−
0.269
4.4
2
−−
−−
−−
−−
3 −−
−−
0.255
1.9
# Points −− 73 −− −− −− 72
# Labs 1 1

Siemens Atellica CH Analyzer • Siemens Atellica CH Ca, REF 11097595
Mean −− 5.81 −− 9.69 −− 13.04
SD
CV
1 −−
−−
0.155
2.7
2−−
−−
0.222
2.3
3 −−
−−
0.234
1.8
# Points −− 1747 −− 1710 −− 116
# Labs 3 2 2

Mean 6.09 6.08 9.56 9.62 12.63 12.65
SD
CV
1 0.230
3.8
0.216
3.5
2 0.216
2.3
0.229
2.4
3 0.353
2.8
0.297
2.3
# Points 1811 111K 421 18021 1590 97932
# Labs 57 255 15 58 50 235

Mean 6.18 6.19 9.80 9.79 12.86 12.79
SD
CV
1 0.170
2.7
0.162
2.6
2 0.230
2.3
0.227
2.3
3 0.279
2.2
0.275
2.1
# Points 3417 279K 1064 84576 2949 254K
# Labs 90 480 31 145 79 453
Toshiba−TBA
Mean −− 5.96 −− −− 12.60 12.70
SD
CV
1 −−
−−
0.078
1.3
2 −−
−−
−−
−−
3 0.000
0.0
0.120
0.9
# Points −− 360 −− −− 1 361
# Labs 1 1 1
Method Group • o−cresolphthalein complexone

Mean 6.14 6.15 9.73 9.77 12.78 12.77
SD
CV
1 0.211
3.4
0.192
3.1
2 0.262
2.7
0.240
2.5
3 0.332
2.6
0.297
2.3
# Points 5443 420K 1656 123K 4730 376K
# Labs 156 816 53 256 137 764
Carbamazepine (Tegretol) Chemiluminescence µg/mL

Mean −− 21.73 −− 75.31 −− 187.7
SD
CV
1 −−
−−
2.99
13.8
2 −−
−−
8.55
11.3
3 −−
−−
20.05
10.7
# Points −− 402 −− 279 −− 285
# Labs 1 1 1

Mean −− 3.63 −− −− −− 13.52
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− 1 −− −− −− 1
# Labs 1 1

Mean −− 21.69 −− 75.31 −− 187.1
SD
CV
1 −−
−−
3.12
14.4
2 −−
−−
8.55
11.3
3 −−
−−
22.51
12.0
# Points −− 403 −− 279 −− 286
# Labs 2 1 2
Carbamazepine (Tegretol) EIA µg/mL

Mean −− 4.06 −− 9.00 −− 14.19
SD
CV
1 −−
−−
0.282
7.0
2 −−
−−
0.420
4.7
3 −−
−−
0.615
4.3
# Points −− 146 −− 143 −− 146
# Labs 1 1 1

Mean 3.82 3.90 8.50 8.66 13.46 13.79
SD
CV
1 0.276
7.2
0.423
10.8
2 0.724
8.5
0.532
6.1
3 1.37
10.2
1.44
10.5
# Points 87 6197 56 2014 88 6096
# Labs 3 20 2 6 3 20
Beckman Coulter AU Series • Alternate Calibration

Mean −− 3.91 −− 8.79 −− −−
SD
CV
1 −−
−−
0.295
7.6
2 −−
−−
0.786
8.9
3 −−
−−
−−
−−
# Points −− 45 −− 46 −− −−
# Labs 2 2
Beckman Coulter AU Series • Emit 2000 Carbamazepine, REF OSR4F229

Mean 3.88 3.87 8.68 8.77 14.12 13.81
SD
CV
1 0.209
5.4
0.292
7.5
0.469
5.4
2
0.592
6.7
3 0.785
5.6
1.06
7.7
# Points 65 2360 31 464 36 2380
# Labs 2 13 1 5 1 10

Mean −− 3.67 −− 8.72 −− 14.28
SD
CV
1 −−
−−
0.196
5.3
2 −−
−−
0.335
3.8
3 −−
−−
0.540
3.8
# Points −− 535 −− 193 −− 529
# Labs 3 2 3

Mean −− 3.82 −− 9.17 −− 14.35
SD
CV
1 −−
−−
0.112
2.9
2 −−
−−
0.301
3.3
3 −−
−−
0.395
2.8
# Points −− 537 −− 558 −− 587
# Labs 2 2 2

Mean −− 3.89 −− 8.76 −− 13.67
SD
CV
1 −−
−−
0.408
10.5
2 −−
−−
0.611
7.0
3 −−
−−
0.911
6.7
# Points −− 699 −− 695 −− 690
# Labs 2 2 2

Mean −− 3.53 −− 8.00 −− 12.03
SD
CV
1 −−
−−
0.893
25.3
2 −−
−−
0.497
6.2
3 −−
−−
0.742
6.2
# Points −− 373 −− 253 −− 474
# Labs 4 2 3

Mean −− 3.37 −− −− −− 11.90
SD
CV
1 −−
−−
0.232
6.9
2 −−
−−
−−
−−
3 −−
−−
0.856
7.2
# Points −− 254 −− −− −− 265
# Labs 6 6

Mean −− 3.35 −− 0.623 −− 12.16
SD
CV
1 −−
−−
0.232
6.9
2 −−
−−
0.076
12.1
3 −−
−−
0.696
5.7
# Points −− 503 −− 184 −− 499
# Labs 6 1 6

Mean −− 3.23 −− 8.00 −− 12.17
SD
CV
1 −−
−−
0.174
5.4
2 −−
−−
0.339
4.2
3 −−
−−
0.799
6.6
# Points −− 930 −− 161 −− 1048
# Labs 10 5 12

Mean −− 3.49 −− 7.99 −− 12.74
SD
CV
1 −−
−−
0.236
6.8
2 −−
−−
0.379
4.7
3 −−
−−
0.744
5.8
# Points −− 1090 −− 611 −− 1394
# Labs 10 11 18

Mean −− 3.32 −− 7.87 −− 13.06
SD
CV
1 −−
−−
0.176
5.3
2 −−
−−
0.386
4.9
3 −−
−−
0.749
5.7
# Points −− 427 −− 613 −− 973
# Labs 6 6 11

Mean −− 3.46 −− 8.36 −− 13.04
SD
CV
1 −−
−−
0.224
6.5
2 −−
−−
0.416
5.0
3 −−
−−
0.554
4.2
# Points −− 1538 −− 656 −− 1873
# Labs 15 5 16

Mean −− 3.46 −− 8.09 −− 12.87
SD
CV
1 −−
−−
0.208
6.0
2 −−
−−
0.515
6.4
3 −−
−−
0.819
6.4
# Points −− 585 −− 854 −− 1173
# Labs 11 9 16

Mean −− 3.47 −− 7.95 −− 12.82
SD
CV
1 −−
−−
0.162
4.7
2 −−
−−
0.644
8.1
3 −−
−−
0.781
6.1
# Points −− 260 −− 116 −− 363
# Labs 3 3 5

Mean −− 3.52 −− 8.48 −− 13.21
SD
CV
1 −−
−−
0.248
7.0
2 −−
−−
0.385
4.5
3 −−
−−
0.565
4.3
# Points −− 241 −− 173 −− 351
# Labs 4 3 6

Mean −− 3.39 −− 8.02 −− 12.63
SD
CV
1 −−
−−
0.202
6.0
2 −−
−−
0.483
6.0
3 −−
−−
0.573
4.5
# Points −− 268 −− 139 −− 129
# Labs 3 1 2

Mean −− 3.36 −− 7.76 −− 12.57
SD
CV
1 −−
−−
0.264
7.8
2 −−
−−
0.575
7.4
3 −−
−−
0.677
5.4
# Points −− 767 −− 186 −− 832
# Labs 10 4 13

Mean 3.37 3.28 8.14 7.70 12.69 12.24
SD
CV
1 0.178
5.3
0.166
5.0
2 0.298
3.7
0.403
5.2
3 0.671
5.3
0.603
4.9
# Points 87 532 31 338 64 493
# Labs 5 7 1 3 4 9

Mean 3.08 3.30 −− −− 11.60 12.45
SD
CV
1 0.047
1.5
0.120
3.6
2 −−
−−
−−
−−
3 0.091
0.8
0.468
3.8
# Points 2 34 −− −− 3 35
# Labs 1 2 1 2

Mean −− −− −− 7.62 −− 12.40
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.309
4.1
3 −−
−−
0.408
3.3
# Points −− −− −− 96 −− 93
# Labs 1 1

Mean −− 3.80 −− −− −− 12.95
SD
CV
1 −−
−−
0.350
9.2
2 −−
−−
−−
−−
3 −−
−−
0.566
4.4
# Points −− 105 −− −− −− 104
# Labs 1 1

Mean −− 3.82 −− −− −− 12.88
SD
CV
1 −−
−−
0.217
5.7
2 −−
−−
−−
−−
3 −−
−−
0.315
2.4
# Points −− 36 −− −− −− 37
# Labs 1 1

Mean −− 3.32 −− −− −− 11.39
SD
CV
1 −−
−−
0.139
4.2
2 −−
−−
−−
−−
3 −−
−−
0.370
3.2
# Points −− 57 −− −− −− 64
# Labs 1 1

Mean −− 3.33 −− −− −− 11.82
SD
CV
1 −−
−−
0.165
5.0
2 −−
−−
−−
−−
3 −−
−−
0.485
4.1
# Points −− 52 −− −− −− 55
# Labs 1 1

Mean −− 3.43 −− −− −− 11.98
SD
CV
1 −−
−−
0.100
2.9
2 −−
−−
−−
−−
3 −−
−−
0.447
3.7
# Points −− 22 −− −− −− 23
# Labs 1 1

Mean −− 3.68 −− −− −− 12.06
SD
CV
1 −−
−−
0.170
4.6
2 −−
−−
−−
−−
3 −−
−−
0.372
3.1
# Points −− 55 −− −− −− 58
# Labs 1 1

Mean −− 3.44 −− −− −− 11.58
SD
CV
1 −−
−−
0.138
4.0
2 −−
−−
−−
−−
3 −−
−−
0.374
3.2
# Points −− 27 −− −− −− 28
# Labs 1 1

Mean −− 3.39 −− −− −− 11.55
SD
CV
1 −−
−−
0.162
4.8
2 −−
−−
−−
−−
3 −−
−−
0.545
4.7
# Points −− 125 −− −− −− 131
# Labs 2 2

Mean −− 3.31 −− −− −− 11.28
SD
CV
1 −−
−−
0.151
4.5
2 −−
−−
−−
−−
3 −−
−−
0.430
3.8
# Points −− 153 −− −− −− 155
# Labs 1 1

Mean −− 3.44 −− −− −− 11.25
SD
CV
1 −−
−−
0.155
4.5
2 −−
−−
−−
−−
3 −−
−−
0.466
4.1
# Points −− 175 −− −− −− 175
# Labs 2 2

Mean −− 3.38 −− −− −− 11.28
SD
CV
1 −−
−−
0.144
4.3
2 −−
−−
−−
−−
3 −−
−−
0.356
3.2
# Points −− 94 −− −− −− 91
# Labs 2 2

Mean −− 3.27 −− −− −− 11.09
SD
CV
1 −−
−−
0.098
3.0
2 −−
−−
−−
−−
3 −−
−−
0.331
3.0
# Points −− 45 −− −− −− 49
# Labs 2 2

Mean 3.67 3.66 8.46 8.23 13.30 13.20
SD
CV
1 0.324
8.8
0.417
11.4
2 0.605
7.2
1.30
15.8
3 1.20
9.0
1.24
9.4
# Points 241 19222 118 8416 191 21358
# Labs 11 154 4 71 9 179
Carbamazepine (Tegretol) Immunonephelometric, kinetic µg/mL

Mean −− 3.63 −− 8.50 −− 12.83
SD
CV
1 −−
−−
0.198
5.5
2 −−
−−
0.312
3.7
3 −−
−−
0.564
4.4
# Points −− 39 −− 38 −− 39
# Labs 1 1 1

Mean −− 3.63 −− 8.50 −− 12.83
SD
CV
1 −−
−−
0.198
5.5
2 −−
−−
0.312
3.7
3 −−
−−
0.564
4.4
# Points −− 39 −− 38 −− 39
# Labs 1 1 1
Carbamazepine (Tegretol) Immunoturbidimetric µg/mL

Mean −− 4.51 −− 9.74 −− 15.08
SD
CV
1 −−
−−
0.247
5.5
2 −−
−−
0.358
3.7
3 −−
−−
0.490
3.3
# Points −− 966 −− 1031 −− 961
# Labs 4 4 4

Mean −− 3.87 −− 8.74 −− 13.81
SD
CV
1 −−
−−
0.181
4.7
2 −−
−−
0.422
4.8
3 −−
−−
0.711
5.1
# Points −− 683 −− 652 −− 706
# Labs 2 2 2

Mean −− 3.38 −− 8.42 −− 13.07
SD
CV
1 −−
−−
0.203
6.0
2 −−
−−
0.350
4.2
3 −−
−−
0.564
4.3
# Points −− 2216 −− 197 −− 2233
# Labs 10 4 10
Carbamazepine (Tegretol) Immunoturbidimetric µg/mL

Hitachi Chemistry Series • Sekisui Nanopia
Mean −− 3.82 −− −− −− −−
SD
CV
1 −−
−−
0.260
6.8
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 65 −− −− −− −−
# Labs 1

Mean −− 3.83 −− 8.74 −− 13.60
SD
CV
1 −−
−−
0.334
8.7
2 −−
−−
0.574
6.6
3 −−
−−
0.845
6.2
# Points −− 1180 −− 908 −− 610
# Labs 5 5 3

Mean 3.76 3.77 8.45 8.49 −− 13.46
SD
CV
1 0.073
2.0
0.131
3.5
2 0.071
0.8
0.281
3.3
3 −−
−−
0.397
2.9
# Points 4 1866 4 1082 −− 1756
# Labs 2 12 2 6 9

Mean 3.73 3.63 −− 8.26 13.48 13.19
SD
CV
1 0.192
5.2
0.245
6.7
2 −−
−−
0.298
3.6
3 0.513
3.8
0.686
5.2
# Points 65 3279 −− 387 65 2895
# Labs 2 15 3 2 14

Mean 3.73 3.77 8.59 8.65 13.34 13.59
SD
CV
1 0.351
9.4
0.218
5.8
2 0.366
4.3
0.419
4.8
3 0.781
5.9
0.659
4.9
# Points 58 25027 48 7538 84 23532
# Labs 5 105 3 28 5 103

Mean 3.73 3.75 8.58 8.73 13.40 13.56
SD
CV
1 0.273
7.3
0.275
7.3
2 0.354
4.1
0.526
6.0
3 0.679
5.1
0.717
5.3
# Points 127 35279 52 11789 149 32693
# Labs 9 154 5 52 7 145
Carbamazepine (Tegretol) KIMS (Roche) µg/mL

Mean 3.87 3.70 9.01 8.91 14.56 14.16
SD
CV
1 0.137
3.5
0.172
4.7
2 0.184
2.0
0.406
4.6
3 0.359
2.5
0.463
3.3
# Points 141 4268 30 854 141 4086
# Labs 3 11 1 3 3 11
Roche cobas c 303/503 • Roche CARB4, REF 08057435

Mean −− 3.81 −− −− −− 14.40
SD
CV
1 −−
−−
0.143
3.8
2 −−
−−
−−
−−
3 −−
−−
0.484
3.4
# Points −− 1305 −− −− −− 1317
# Labs 5 6

Mean 3.87 3.72 9.01 8.91 14.56 14.22
SD
CV
1 0.137
3.5
0.172
4.6
2 0.184
2.0
0.406
4.6
3 0.359
2.5
0.479
3.4
# Points 141 5573 30 854 141 5403
# Labs 3 16 1 3 3 17
Ceruloplasmin Immunonephelometric, end point mg/dL

Mean −− −− 21.91 21.82 27.78 27.65
SD
CV
1 −−
−−
−−
−−
2 0.610
2.8
0.618
2.8
3 0.570
2.1
0.728
2.6
# Points −− −− 62 573 62 580
# Labs 2 2 2 2

Mean −− −− 21.91 21.82 27.78 27.65
SD
CV
1 −−
−−
−−
−−
2 0.610
2.8
0.618
2.8
3 0.570
2.1
0.728
2.6
# Points −− −− 62 573 62 580
# Labs 2 2 2 2
Ceruloplasmin Immunoturbidimetric mg/dL

Mean −− 15.83 −− 22.30 −− 27.84
SD
CV
1 −−
−−
1.22
7.7
2 −−
−−
1.47
6.6
3 −−
−−
1.57
5.7
# Points −− 167 −− 164 −− 159
# Labs 2 2 2

Mean −− 13.72 −− −− −− 23.66
SD
CV
1 −−
−−
0.262
1.9
2 −−
−−
−−
−−
3 −−
−−
0.323
1.4
# Points −− 406 −− −− −− 406
# Labs 1 1

Mean −− 14.33 −− 22.30 −− 24.84
SD
CV
1 −−
−−
1.18
8.2
2 −−
−−
1.47
6.6
3 −−
−−
2.08
8.4
# Points −− 573 −− 164 −− 565
# Labs 3 2 3
Chloride Colorimetric mEq/L

Mean −− 69.30 −− −− −− 116.1
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− 1 −− −− −− 1
# Labs 1 1

Mean −− 78.60 −− −− −− 123.3
SD
CV
1 −−
−−
2.14
2.7
2 −−
−−
−−
−−
3 −−
−−
1.42
1.2
# Points −− 191 −− −− −− 181
# Labs 1 1

Mean −− 78.55 −− −− −− 123.2
SD
CV
1 −−
−−
2.24
2.8
2 −−
−−
−−
−−
3 −−
−−
1.51
1.2
# Points −− 192 −− −− −− 182
# Labs 2 2
Chloride Enzymatic mEq/L

Mean −− 78.14 −− −− −− 142.0
SD
CV
1 −−
−−
1.37
1.8
2 −−
−−
−−
−−
3 −−
−−
67.77
47.7
# Points −− 59 −− −− −− 73
# Labs 1 1
Chloride Enzymatic mEq/L

Mean −− 78.14 −− −− −− 142.0
SD
CV
1 −−
−−
1.37
1.8
2 −−
−−
−−
−−
3 −−
−−
67.77
47.7
# Points −− 59 −− −− −− 73
# Labs 1 1
Chloride ISE direct mEq/L

Mean −− 76.53 −− 102.7 −− 118.7
SD
CV
1 −−
−−
1.25
1.6
2 −−
−−
0.923
0.9
3 −−
−−
1.31
1.1
# Points −− 314 −− 265 −− 476
# Labs 4 5 6

Mean 74.95 74.95 100.8 101.2 −− 117.7
SD
CV
1 1.70
2.3
1.44
1.9
2 2.03
2.0
1.34
1.3
3 −−
−−
1.71
1.5
# Points 20 1616 20 2464 −− 2631
# Labs 1 8 1 11 13

Mean −− 73.36 −− −− −− 115.7
SD
CV
1 −−
−−
2.78
3.8
2 −−
−−
−−
−−
3 −−
−−
4.46
3.9
# Points −− 218 −− −− −− 218
# Labs 1 1
DIAMOND PROLYTE
Mean 81.14 79.44 105.5 105.5 120.5 119.5
SD
CV
1 1.64
2.0
2.50
3.1
2 1.51
1.4
2.09
2.0
3 0.620
0.5
1.25
1.0
# Points 20 229 18 190 5 42
# Labs 1 2 1 2 1 1

Mean 77.60 78.32 105.9 106.0 −− −−
SD
CV
1 0.000
0.0
1.89
2.4
2 0.000
0.0
0.495
0.5
3 −−
−−
−−
−−
# Points 10 254 10 188 −− −−
# Labs 1 1 1 1

Mean 74.83 75.69 102.0 104.7 −− −−
SD
CV
1 1.72
2.3
1.17
1.5
2 1.41
1.4
2.21
2.1
3 −−
−−
−−
−−
# Points 6 175 5 213 −− −−
# Labs 1 3 1 4
Fuji Dri−Chem Series • Fuji Dri−Chem Na−K−Cl, REF 897N203654A

Mean 74.45 74.87 102.9 103.0 −− −−
SD
CV
1 0.826
1.1
2.43
3.2
1.37
1.3
22.86
2.8
3 −−
−−
−−
−−
# Points 20 38 20 39 −− −−
# Labs 1 1 1 2

Mean −− 74.02 −− −− −− 119.3
SD
CV
1 −−
−−
1.19
1.6
2 −−
−−
−−
−−
3 −−
−−
1.12
0.9
# Points −− 636 −− −− −− 628
# Labs 2 2

Mean −− 75.86 −− −− −− 123.7
SD
CV
1 −−
−−
1.21
1.6
2 −−
−−
−−
−−
3 −−
−−
1.75
1.4
# Points −− 37 −− −− −− 37
# Labs 1 1

Medica EasyLyte Series/Expand
Mean −− 74.21 −− 105.7 −− 125.6
SD
CV
1 −−
−−
2.12
2.9
2 −−
−−
1.73
1.6
3 −−
−−
2.36
1.9
# Points −− 425 −− 423 −− 422
# Labs 3 3 3
RANDOX RX daytona
Mean 73.81 79.26 101.8 103.0 116.0 116.0
SD
CV
1 1.18
1.6
6.01
7.6
2 0.713
0.7
4.27
4.1
3 0.141
0.1
0.141
0.1
# Points 19 171 14 145 2 2
# Labs 1 1 1 1 1 1
RANDOX RX imola
Mean 77.27 76.92 104.2 103.8 −− −−
SD
CV
1 0.545
0.7
0.964
1.3
2 0.428
0.4
0.761
0.7
3 −−
−−
−−
−−
# Points 26 222 24 192 −− −−
# Labs 1 1 1 1
Roche AVL 9100 Series

Mean −− 75.88 −− 101.1 −− −−
SD
CV
1 −−
−−
1.69
2.2
2 −−
−−
0.806
0.8
3 −−
−−
−−
−−
# Points −− 17 −− 16 −− −−
# Labs 1 1
SFRI − ISE Series

Mean −− 78.58 −− 101.7 −− 121.3
SD
CV
1 −−
−−
1.06
1.4
2 −−
−−
1.29
1.3
3 −−
−−
1.18
1.0
# Points −− 824 −− 824 −− 824
# Labs 2 2 2

Mean −− −− −− 101.3 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.934
0.9
3 −−
−−
−−
−−
# Points −− −− −− 178 −− −−
# Labs 1
Siemens Dimension Xpand/EXL Series

Mean −− 76.08 −− 105.7 −− 125.9
SD
CV
1 −−
−−
1.20
1.6
2 −−
−−
1.36
1.3
3 −−
−−
1.70
1.3
# Points −− 230 −− 230 −− 230
# Labs 1 1 1

Mean −− −− 106.9 106.9 −− −−
SD
CV
1 −−
−−
−−
−−
2 1.49
1.4
1.49
1.4
3 −−
−−
−−
−−
# Points −− −− 23 32 −− −−
# Labs 1 1
Toshiba−TBA
Mean −− 76.63 −− −− 119.0 118.9
SD
CV
1 −−
−−
0.768
1.0
2 −−
−−
−−
−−
3 0.000
0.0
0.552
0.5
# Points −− 360 −− −− 1 361
# Labs 1 1 1

Mean 77.80 77.02 102.5 104.1 121.0 122.3
SD
CV
1 0.900
1.2
1.40
1.8
2 2.96
2.9
2.97
2.9
3 2.17
1.8
2.07
1.7
# Points 15 1818 56 1805 51 2086
# Labs 1 16 3 13 2 12

Mean 77.50 77.59 −− −− 123.0 122.7
SD
CV
1 1.13
1.5
1.32
1.7
2 −−
−−
−−
−−
3 1.60
1.3
1.37
1.1
# Points 19 584 −− −− 17 535
# Labs 1 1 1 1

Mean 79.11 78.02 107.2 106.5 −− 123.9
SD
CV
1 0.527
0.7
1.18
1.5
2 0.640
0.6
1.38
1.3
3 −−
−−
0.354
0.3
# Points 76 696 77 691 −− 2
# Labs 2 2 2 2 1

Mean 77.71 77.49 105.9 105.6 122.7 122.9
SD
CV
1 1.37
1.8
1.37
1.8
2 1.31
1.2
1.73
1.6
3 1.72
1.4
1.67
1.4
# Points 1324 66406 507 27120 1220 63501
# Labs 55 198 27 87 47 185

Mean 79.24 78.37 107.3 106.9 124.7 123.8
SD
CV
1 1.07
1.3
1.24
1.6
2 1.22
1.1
1.26
1.2
3 1.31
1.0
1.44
1.2
# Points 285 11066 244 4655 237 10900
# Labs 13 95 11 41 11 92

Mean −− 73.30 −− −− −− 116.1
SD
CV
1 −−
−−
0.617
0.8
2 −−
−−
−−
−−
3 −−
−−
0.609
0.5
# Points −− 14 −− −− −− 14
# Labs 1 1

Mean −− −− −− −− −− 130.0
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− −− −− −− −− 1
# Labs 1

Mean −− 76.65 −− −− −− 122.4
SD
CV
1 −−
−−
1.15
1.5
2 −−
−−
−−
−−
3 −−
−−
1.11
0.9
# Points −− 128 −− −− −− 125
# Labs 2 2

Mean 77.92 77.50 105.9 105.3 122.9 122.7
SD
CV
1 1.60
2.1
1.54
2.0
2 2.06
1.9
2.21
2.1
3 1.88
1.5
2.05
1.7
# Points 1840 86478 1018 39670 1533 83033
# Labs 79 349 51 180 64 327
Chloride ISE indirect mEq/L

Mean 77.12 77.02 103.8 103.8 119.9 119.8
SD
CV
1 1.47
1.9
1.06
1.4
2 1.31
1.3
1.23
1.2
3 1.48
1.2
1.37
1.1
# Points 2943 119K 1739 55851 2077 117K
# Labs 79 245 65 166 46 197
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c ICT Diluent, REF 07P53
Mean 77.20 77.46 103.9 104.2 −− −−
SD
CV
1 0.700
0.9
0.650
0.8
2
0.450
0.4
0.762
0.7
3 −−
−−
−−
−−
# Points 26 282 26 286 −− −−
# Labs 1 2 1 3

Mean 75.22 75.29 101.6 101.6 117.8 118.0
SD
CV
1 0.821
1.1
1.03
1.4
2 0.970
1.0
1.10
1.1
3 1.23
1.0
1.32
1.1
# Points 2302 137K 1940 101K 1336 141K
# Labs 76 346 64 251 45 324

Mean −− 75.68 −− 102.2 −− 118.3
SD
CV
1 −−
−−
0.698
0.9
2 −−
−−
1.19
1.2
3 −−
−−
1.26
1.1
# Points −− 554 −− 707 −− 550
# Labs 4 5 4

Mean 75.43 76.06 −− 101.9 119.0 118.4
SD
CV
1 1.62
2.1
1.43
1.9
2 −−
−−
2.13
2.1
3 1.96
1.6
1.65
1.4
# Points 81 15676 −− 4411 81 15043
# Labs 2 34 12 2 32

Mean −− −− −− 101.5 −− 116.3
SD
CV
1 −−
−−
−−
−−
2 −−
−−
3.07
3.0
3 −−
−−
3.51
3.0
# Points −− −− −− 28 −− 28
# Labs 1 1
Dirui CS Series
Mean −− −− 101.0 101.4 112.4 115.5
SD
CV
1 −−
−−
−−
−−
2 1.32
1.3
2.10
2.1
3 2.91
2.6
3.28
2.8
# Points −− −− 39 242 37 242
# Labs 3 3 3 3

Mean −− 73.62 −− −− −− −−
SD
CV
1 −−
−−
0.804
1.1
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 26 −− −− −− −−
# Labs 1

Mean −− 74.30 102.5 102.1 −− 120.0
SD
CV
1 −−
−−
1.72
2.3
2 1.73
1.7
1.99
1.9
3 −−
−−
2.25
1.9
# Points −− 3897 31 3131 −− 4031
# Labs 11 1 8 11

Mean −− −− −− 100.6 −− 118.5
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.58
1.6
3 −−
−−
2.56
2.2
# Points −− −− −− 107 −− 108
# Labs 1 1

Mean −− 68.58 −− −− −− 119.3
SD
CV
1 −−
−−
2.78
4.1
2 −−
−−
−−
−−
3 −−
−−
2.84
2.4
# Points −− 92 −− −− −− 92
# Labs 1 1

Mean −− 73.38 −− −− −− 118.6
SD
CV
1 −−
−−
1.32
1.8
2 −−
−−
−−
−−
3 −−
−−
1.62
1.4
# Points −− 578 −− −− −− 576
# Labs 2 2

Mindray BS Series
Mean 76.39 76.74 103.5 104.0 119.5 120.4
SD
CV
1 0.820
1.1
1.24
1.6
2 1.21
1.2
1.33
1.3
3 1.25
1.0
1.54
1.3
# Points 18 445 18 459 18 459
# Labs 1 3 1 2 1 2

Mean −− −− −− 103.5 −− 120.1
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.07
1.0
3 −−
−−
1.40
1.2
# Points −− −− −− 148 −− 148
# Labs 1 1
Mindray CL Series
Mean −− −− −− 102.7 −− 118.9
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.46
2.4
3 −−
−−
2.68
2.3
# Points −− −− −− 281 −− 281
# Labs 2 2

Mean 73.14 73.11 101.3 100.9 119.2 118.9
SD
CV
1 1.20
1.6
1.28
1.8
2 1.09
1.1
1.28
1.3
3 1.13
0.9
1.25
1.0
# Points 3990 122K 461 52756 3894 131K
# Labs 59 223 11 119 58 246

Mean 73.14 73.31 101.0 101.1 118.4 118.9
SD
CV
1 0.920
1.3
1.26
1.7
2 1.03
1.0
1.15
1.1
3 1.08
0.9
1.18
1.0
# Points 294 11347 249 10192 148 10242
# Labs 8 24 6 17 6 22
Roche cobas c 303/503 • Roche ISE indirect Na−K−Cl, REF 10820652/08392013

Mean 73.33 73.19 101.2 100.4 119.0 118.7
SD
CV
1 0.756
1.0
1.33
1.8
0.770
0.8
2 0.998
1.0
3 0.764
0.6
1.69
1.4
# Points 431 13801 164 3610 312 14011
# Labs 13 35 4 10 10 32

Mean 73.15 73.26 100.7 100.6 117.7 117.7
SD
CV
1 0.991
1.4
0.968
1.3
2 0.904
0.9
1.00
1.0
3 1.27
1.1
1.43
1.2
# Points 199 1888 203 2190 124 1304
# Labs 5 6 5 6 4 6

Mean 76.50 75.69 105.0 103.4 122.2 120.9
SD
CV
1 1.60
2.1
1.31
1.7
2 2.00
1.9
2.05
2.0
3 2.36
1.9
1.91
1.6
# Points 269 10347 120 2818 271 10626
# Labs 3 12 1 2 3 14

Mean 73.65 73.94 102.6 101.4 121.5 119.6
SD
CV
1 0.850
1.2
1.07
1.5
2 0.890
0.9
1.62
1.6
3 0.940
0.8
1.60
1.3
# Points 31 1454 31 1672 31 1845
# Labs 1 5 1 6 1 6
Mean −− 73.70 −− 101.7 −− 119.7
SD
CV
1 −−
−−
2.04
2.8
2 −−
−−
2.49
2.4
3 −−
−−
2.76
2.3
# Points −− 539 −− 647 −− 915
# Labs 2 3 3

Mean −− −− −− 98.23 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.22
1.2
3 −−
−−
−−
−−
# Points −− −− −− 24 −− −−
# Labs 1

Mean 76.27 76.13 103.5 103.1 119.2 119.9
SD
CV
1 2.64
3.5
0.930
1.2
2 2.10
2.0
1.15
1.1
3 2.12
1.8
1.25
1.0
# Points 146 16729 148 13164 122 17262
# Labs 5 41 5 35 4 39

Mean 78.59 77.29 104.9 104.0 120.1 120.3
SD
CV
1 1.42
1.8
1.57
2.0
2 1.32
1.3
1.57
1.5
3 1.40
1.2
1.79
1.5
# Points 684 40618 448 21818 357 30046
# Labs 17 99 15 70 10 79
Siemens Atellica CH Analyzer • Siemens Atellica CH A−LYTE IMT Na K Cl, REF 11099315
Mean −− 77.36 −− −− −− 119.6
SD
CV
1 −−
−−
1.35
1.7
2−−
−−
−−
−−
3 −−
−−
1.31
1.1
# Points −− 186 −− −− −− 186
# Labs 2 2

Mean −− 74.68 −− 102.8 −− 123.3
SD
CV
1 −−
−−
1.27
1.7
2 −−
−−
0.839
0.8
3 −−
−−
1.39
1.1
# Points −− 50 −− 5 −− 76
# Labs 2 1 2

Mean 76.63 76.46 106.1 105.9 123.9 123.6
SD
CV
1 1.03
1.3
1.09
1.4
2 1.34
1.3
1.62
1.5
3 2.03
1.6
1.84
1.5
# Points 3979 319K 1126 96133 3396 290K
# Labs 91 480 32 148 77 451
Siemens Dimension Xpand/EXL Series

Mean 74.39 74.58 103.6 104.0 123.3 123.2
SD
CV
1 1.13
1.5
1.21
1.6
2 1.01
1.0
1.43
1.4
3 1.51
1.2
1.71
1.4
# Points 1841 122K 380 19938 1665 112K
# Labs 56 260 13 64 52 235
Siemens Dimension Xpand/EXL Series • Dilution

Mean −− 75.09 −− −− −− 123.2
SD
CV
1 −−
−−
0.955
1.3
2 −−
−−
−−
−−
3 −−
−−
1.40
1.1
# Points −− 1241 −− −− −− 850
# Labs 2 2
Siemens Dimension Xpand/EXL Series • Reagent, Alternate Formulation/Standardization − Shift DOWN

Mean −− 76.50 −− −− −− 121.0
SD
CV
1 −−
−−
0.707
0.9
2
−−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− 2 −− −− −− 2
# Labs 1 1
Toshiba−TBA
Mean −− −− −− −− −− 113.8
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
1.54
1.4
# Points −− −− −− −− −− 78
# Labs 1

Mean −− 77.16 −− 104.3 −− 120.8
SD
CV
1 −−
−−
0.847
1.1
2 −−
−−
1.03
1.0
3 −−
−−
1.26
1.0
# Points −− 456 −− 460 −− 468
# Labs 3 3 3

Mean 75.36 75.58 103.2 103.2 120.8 121.0
SD
CV
1 2.06
2.7
1.77
2.3
2 2.13
2.1
2.33
2.3
3 2.78
2.3
2.82
2.3
# Points 17234 937K 7123 392K 13869 899K
# Labs 417 1844 228 939 322 1722
Chloride Mercuric thiocyanate, ferric ion mEq/L

ERBA XL−640
Mean −− 79.75 −− 108.8 −− −−
SD
CV
1 −−
−−
1.41
1.8
2 −−
−−
1.72
1.6
3 −−
−−
−−
−−
# Points −− 58 −− 58 −− −−
# Labs 1 1
Method Group • Mercuric thiocyanate, ferric ion

Mean −− 79.75 −− 108.8 −− −−
SD
CV
1 −−
−−
1.41
1.8
2 −−
−−
1.72
1.6
3 −−
−−
−−
−−
# Points −− 58 −− 58 −− −−
# Labs 1 1
Chloride Titrimetric mEq/L

Mean −− 77.12 −− 103.3 −− 119.1
SD
CV
1 −−
−−
0.944
1.2
2 −−
−−
1.57
1.5
3 −−
−−
1.75
1.5
# Points −− 533 −− 546 −− 521
# Labs 2 2 2
Method Group • Titrimetric

Mean −− 77.12 −− 103.3 −− 119.1
SD
CV
1 −−
−−
0.944
1.2
2 −−
−−
1.57
1.5
3 −−
−−
1.75
1.5
# Points −− 533 −− 546 −− 521
# Labs 2 2 2
Cholesterol, HDL Agarose Gel mg/dL

Mean 30.61 29.16 42.55 42.99 −− 68.66
SD
CV
1 0.816
2.7
2.57
8.8
2 1.09
2.6
2.08
4.8
3 −−
−−
1.85
2.7
# Points 26 249 26 155 −− 94
# Labs 1 2 1 1 1

Mean 30.61 29.16 42.55 42.99 −− 68.66
SD
CV
1 0.816
2.7
2.57
8.8
2 1.09
2.6
2.08
4.8
3 −−
−−
1.85
2.7
# Points 26 249 26 155 −− 94
# Labs 1 2 1 1 1
Cholesterol, HDL Dextran sulfate 50K−VITROS mg/dL

Mean −− −− −− 34.32 −− 53.36
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.17
3.4
3 −−
−−
1.59
3.0
# Points −− −− −− 290 −− 290
# Labs 1 1

Mean −− 22.55 −− −− −− 58.45
SD
CV
1 −−
−−
0.905
4.0
2 −−
−−
−−
−−
3 −−
−−
2.51
4.3
# Points −− 140 −− −− −− 141
# Labs 2 2

Mean −− 20.59 −− 34.36 −− 55.49
SD
CV
1 −−
−−
1.41
6.8
2 −−
−−
1.25
3.6
3 −−
−−
2.45
4.4
# Points −− 332 −− 119 −− 333
# Labs 2 1 2

Mean −− 21.84 −− 35.76 −− 56.91
SD
CV
1 −−
−−
1.13
5.2
2 −−
−−
1.18
3.3
3 −−
−−
2.49
4.4
# Points −− 419 −− 99 −− 414
# Labs 3 1 3

Mean −− 21.46 −− 32.97 −− 56.33
SD
CV
1 −−
−−
1.34
6.3
2 −−
−−
2.26
6.9
3 −−
−−
3.46
6.1
# Points −− 780 −− 236 −− 792
# Labs 5 2 6

Mean −− 19.72 −− 33.55 −− 55.60
SD
CV
1 −−
−−
0.810
4.1
2 −−
−−
1.10
3.3
3 −−
−−
1.57
2.8
# Points −− 141 −− 139 −− 139
# Labs 1 1 1

Mean −− 21.22 −− 35.08 −− 55.25
SD
CV
1 −−
−−
1.08
5.1
2 −−
−−
2.07
5.9
3 −−
−−
2.63
4.8
# Points −− 154 −− 127 −− 151
# Labs 3 2 3

Mean −− 20.84 −− 33.71 −− 53.79
SD
CV
1 −−
−−
0.645
3.1
2 −−
−−
1.09
3.2
3 −−
−−
1.51
2.8
# Points −− 150 −− 150 −− 152
# Labs 1 1 1

Mean 19.80 20.93 30.00 32.57 −− 251.0
SD
CV
1 1.70
8.6
1.40
6.7
2 3.54
11.8
1.71
5.3
3 −−
−−
0.000
0.0
# Points 4 161 4 166 −− 1
# Labs 1 3 1 3 1

Mean −− 21.05 −− 34.26 −− 55.77
SD
CV
1 −−
−−
0.964
4.6
2 −−
−−
1.72
5.0
3 −−
−−
2.19
3.9
# Points −− 254 −− 238 −− 232
# Labs 2 2 1

Mean 22.82 22.22 35.58 34.20 −− 53.01
SD
CV
1 0.940
4.1
1.54
6.9
2 1.75
4.9
1.65
4.8
3 −−
−−
0.936
1.8
# Points 31 134 30 133 −− 35
# Labs 1 2 1 2 1

Mean −− 18.42 −− −− −− 48.17
SD
CV
1 −−
−−
0.962
5.2
2 −−
−−
−−
−−
3 −−
−−
1.91
4.0
# Points −− 128 −− −− −− 126
# Labs 2 2
Method Group • Dextran sulfate 50K−VITROS

Mean 22.47 21.16 34.93 33.98 −− 55.50
SD
CV
1 1.41
6.3
1.48
7.0
2 2.67
7.7
1.80
5.3
3 −−
−−
4.93
8.9
# Points 35 2811 34 1716 −− 2825
# Labs 2 26 2 16 24
Cholesterol, HDL Dextran Sulfate, 3,000 mg/dL

Mean −− 28.84 −− 41.11 −− 65.41
SD
CV
1 −−
−−
1.09
3.8
2 −−
−−
1.88
4.6
3 −−
−−
2.51
3.8
# Points −− 37 −− 37 −− 37
# Labs 1 1 1
Method Group • Dextran Sulfate, 3,000

Mean −− 28.84 −− 41.11 −− 65.41
SD
CV
1 −−
−−
1.09
3.8
2 −−
−−
1.88
4.6
3 −−
−−
2.51
3.8
# Points −− 37 −− 37 −− 37
# Labs 1 1 1
Cholesterol, HDL Direct Enzymatic Colorimetric mg/dL

Mean 30.15 30.33 41.91 42.69 62.63 66.41
SD
CV
1 1.21
4.0
1.82
6.0
2 1.48
3.5
2.46
5.8
3 1.54
2.5
3.59
5.4
# Points 150 3559 148 2912 19 2805
# Labs 6 19 6 12 1 12
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH Ultra HDL REF 3K33
Mean 28.39 29.17 39.11 40.56 −− −−
SD
CV
1 0.874
3.1
1.69
5.8
2
1.00
2.6
2.60
6.4
3 −−
−−
−−
−−
# Points 18 201 18 202 −− −−
# Labs 1 1 1 1
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c Ultra HDL, REF 07P75
Mean −− 30.88 −− −− −− 68.31
SD
CV
1 −−
−−
1.68
5.4
2 −−
−−
−−
−−
3 −−
−−
2.63
3.8
# Points −− 219 −− −− −− 216
# Labs 1 1

Mean −− 27.27 −− 39.96 −− 63.57
SD
CV
1 −−
−−
2.71
9.9
2 −−
−−
2.33
5.8
3 −−
−−
4.87
7.7
# Points −− 2395 −− 2183 −− 2723
# Labs 13 12 16

Mean −− 24.86 −− 40.56 −− 65.34
SD
CV
1 −−
−−
1.59
6.4
2 −−
−−
1.85
4.6
3 −−
−−
3.00
4.6
# Points −− 576 −− 587 −− 581
# Labs 4 4 4

Beckman Coulter AU Series • Randox
Mean −− 22.20 −− 34.03 −− 54.10
SD
CV
1 −−
−−
1.08
4.9
2 −−
−−
1.43
4.2
3 −−
−−
1.56
2.9
# Points −− 11 −− 11 −− 11
# Labs 1 1 1

Mean −− 28.87 −− −− −− 65.65
SD
CV
1 −−
−−
0.924
3.2
2 −−
−−
−−
−−
3 −−
−−
2.40
3.7
# Points −− 296 −− −− −− 296
# Labs 1 1
Beckman Coulter UniCel DxC Series • BC DxC HDL, REF A15625

Mean 29.24 29.60 −− −− 65.86 66.13
SD
CV
1 0.641
2.2
0.995
3.4
−−
−−
2 −−
−−
3 0.822
1.2
2.34
3.5
# Points 37 667 −− −− 37 664
# Labs 1 1 1 1

Mean −− −− −− 38.90 −− 58.64
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.545
1.4
3 −−
−−
1.09
1.9
# Points −− −− −− 172 −− 170
# Labs 1 1
Dirui CS Series
Mean −− 25.02 −− 36.82 −− 56.18
SD
CV
1 −−
−−
2.02
8.1
2 −−
−−
2.53
6.9
3 −−
−−
3.36
6.0
# Points −− 790 −− 780 −− 732
# Labs 2 2 2

Mean 31.36 31.65 37.58 44.48 68.60 72.83
SD
CV
1 4.11
13.1
4.73
15.0
2 2.71
7.2
6.07
13.6
3 4.22
6.2
5.35
7.3
# Points 44 451 12 349 5 42
# Labs 2 3 1 3 1 2

Mean 20.16 22.30 30.46 33.60 −− −−
SD
CV
1 1.86
9.2
1.94
8.7
2 2.60
8.5
2.45
7.3
3 −−
−−
−−
−−
# Points 25 119 24 118 −− −−
# Labs 1 3 1 3

Mean −− 27.05 −− 37.11 −− 60.23
SD
CV
1 −−
−−
1.36
5.0
2 −−
−−
0.806
2.2
3 −−
−−
2.66
4.4
# Points −− 666 −− 48 −− 666
# Labs 3 1 3
Hitachi Chemistry Series • Hitachi Medical Medex

Mean −− 22.74 −− −− −− −−
SD
CV
1 −−
−−
0.314
1.4
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 75 −− −− −− −−
# Labs 1

Mean 21.74 21.80 29.64 30.59 41.27 42.01
SD
CV
1 0.517
2.4
0.924
4.2
2 1.16
3.9
1.25
4.1
3 1.61
3.9
2.37
5.6
# Points 176 1275 92 518 148 1141
# Labs 6 7 3 5 5 7

Roche cobas 6000/c 311 • Roche HDLC4
Mean 20.00 23.04 28.00 28.17 39.00 45.75
SD
CV
1 0.000
0.0
0.892
3.9
2 0.000
0.0
0.408
1.4
3 0.000
0.0
1.95
4.3
# Points 1 114 1 6 1 115
# Labs 1 2 1 1 1 2
Roche cobas 8000

Mean −− 21.46 −− 29.14 −− 42.65
SD
CV
1 −−
−−
0.784
3.7
2 −−
−−
1.16
4.0
3 −−
−−
1.90
4.5
# Points −− 1365 −− 575 −− 1273
# Labs 4 1 4
Roche cobas 8000 • Roche HDLC4

Mean −− 22.46 −− −− −− 44.54
SD
CV
1 −−
−−
1.08
4.8
2 −−
−−
−−
−−
3 −−
−−
2.02
4.5
# Points −− 526 −− −− −− 531
# Labs 2 2

Mean −− 25.02 −− −− −− 51.45
SD
CV
1 −−
−−
14.65
58.5
2 −−
−−
−−
−−
3 −−
−−
39.23
76.2
# Points −− 1039 −− −− −− 1028
# Labs 2 2
Roche cobas c 303/503 • Roche HDLC4

Mean −− 22.05 −− −− −− 43.42
SD
CV
1 −−
−−
0.772
3.5
2 −−
−−
−−
−−
3 −−
−−
1.72
4.0
# Points −− 333 −− −− −− 341
# Labs 2 2
Roche cobas c 303/503 • Roche HDLC4. REF 08057877

Mean 21.08 21.90 −− −− 40.39 43.34
SD
CV
1 0.764
3.6
1.20
5.5
2 −−
−−
−−
−−
3 1.74
4.3
2.50
5.8
# Points 185 1868 −− −− 75 1681
# Labs 4 4 2 2

Mean 20.88 21.16 29.39 29.81 40.22 40.84
SD
CV
1 0.387
1.9
0.469
2.2
2 0.773
2.6
0.963
3.2
3 1.55
3.8
1.41
3.5
# Points 39 418 46 427 48 431
# Labs 1 1 1 1 1 1

Mean −− 23.18 −− 35.20 −− 53.94
SD
CV
1 −−
−−
0.703
3.0
2 −−
−−
1.07
3.0
3 −−
−−
1.81
3.4
# Points −− 403 −− 511 −− 510
# Labs 1 1 1

Mean −− 23.42 44.31 44.47 67.47 58.28
SD
CV
1 −−
−−
0.801
3.4
2 1.64
3.7
0.994
2.2
3 1.72
2.6
3.29
5.6
# Points −− 328 9 383 3 361
# Labs 1 2 2 1 2
Siemens Atellica CH Analyzer • Siemens Atellica CH HDLC , REF 11537213

Mean −− 30.69 −− −− −− 69.87
SD
CV
1 −−
−−
0.589
1.9
2
−−
−−
−−
−−
3 −−
−−
1.69
2.4
# Points −− 159 −− −− −− 164
# Labs 1 1

Thermo Konelab 20/30/60i • Sekisui Diagnostics SEKURE
Mean −− −− 41.61 41.61 −− −−
SD
CV
1 −−
−−
−−
−−
3.32
8.0
2 3.32
8.0
3 −−
−−
−−
−−
# Points −− −− 20 20 −− −−
# Labs 1 1

Mean 20.89 21.27 33.13 33.72 −− −−
SD
CV
1 1.13
5.4
1.24
5.8
2 0.948
2.9
1.41
4.2
3 −−
−−
−−
−−
# Points 25 48 25 48 −− −−
# Labs 1 1 1 1
Method Group • Direct Enzymatic Colorimetric

Mean 24.40 25.90 36.09 38.94 45.47 56.08
SD
CV
1 4.48
18.4
4.05
15.6
2 6.03
16.7
5.19
13.3
3 9.76
21.5
10.83
19.3
# Points 700 16862 395 9850 336 15454
# Labs 24 79 18 53 13 68
Cholesterol, HDL Direct measure, immunoinhibition mg/dL

Mean −− −− −− 42.65 −− 67.61
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.23
2.9
3 −−
−−
1.92
2.8
# Points −− −− −− 202 −− 202
# Labs 2 2

Mean 27.71 28.61 41.27 41.80 65.27 66.30
SD
CV
1 2.07
7.5
2.19
7.6
2 1.88
4.6
2.08
5.0
3 2.61
4.0
3.41
5.1
# Points 94 20814 54 20772 68 23073
# Labs 4 30 4 31 4 34

Mean −− −− 37.41 37.59 58.78 59.66
SD
CV
1 −−
−−
−−
−−
2
0.714
1.9
1.09
2.9
3 1.07
1.8
1.92
3.2
# Points −− −− 87 885 87 886
# Labs 2 2 2 2

Mean −− 27.74 −− −− −− 63.12
SD
CV
1 −−
−−
1.29
4.7
2 −−
−−
−−
−−
3 −−
−−
2.54
4.0
# Points −− 217 −− −− −− 196
# Labs 1 1
Beckman Coulter AU Series • Beckman Coulter AU HDL, OSR6X87

Mean 26.86 26.52 40.97 42.31 64.35 66.76
SD
CV
1 2.54
9.5
2.46
9.3
1.66
4.1
2 1.99
4.7
3 1.94
3.0
3.35
5.0
# Points 216 6790 217 19790 161 21309
# Labs 5 28 5 50 3 46

Mean 30.01 29.99 42.01 42.51 66.83 67.54
SD
CV
1 0.711
2.4
0.858
2.9
0.936
2.2
2 1.10
2.6
3 1.59
2.4
1.78
2.6
# Points 86 1920 85 1915 85 1915
# Labs 2 2 2 2 2 2

Mean −− 25.55 −− −− −− 54.91
SD
CV
1 −−
−−
0.442
1.7
2 −−
−−
−−
−−
3 −−
−−
1.80
3.3
# Points −− 792 −− −− −− 724
# Labs 1 1
Cholesterol, HDL Direct measure, immunoinhibition mg/dL

Mean −− 21.30 −− −− −− −−
SD
CV
1 −−
−−
1.32
6.2
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 25 −− −− −− −−
# Labs 1

Mean −− 30.00 −− −− −− 66.68
SD
CV
1 −−
−−
1.17
3.9
2 −−
−−
−−
−−
3 −−
−−
2.30
3.5
# Points −− 252 −− −− −− 253
# Labs 1 1

Mean −− 23.75 −− −− −− 52.26
SD
CV
1 −−
−−
0.718
3.0
2 −−
−−
−−
−−
3 −−
−−
2.01
3.9
# Points −− 88 −− −− −− 90
# Labs 1 1

Mean −− −− −− 34.22 −− 52.69
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.412
1.2
3 −−
−−
0.818
1.6
# Points −− −− −− 86 −− 88
# Labs 1 1
Roche cobas 8000 • Randox

Mean −− −− −− 36.98 −− 53.83
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.50
4.1
3 −−
−−
4.15
7.7
# Points −− −− −− 398 −− 412
# Labs 1 1

Mean 21.58 21.59 29.20 30.38 −− −−
SD
CV
1 0.425
2.0
0.766
3.5
2 0.580
2.0
1.10
3.6
3 −−
−−
−−
−−
# Points 106 1187 107 1201 −− −−
# Labs 1 1 1 1
Roche Hitachi/MODULAR • Sekisui Diagnostics SEKURE

Mean −− 30.27 −− −− −− 67.35
SD
CV
1 −−
−−
1.10
3.6
2 −−
−−
−−
−−
3 −−
−−
2.64
3.9
# Points −− 278 −− −− −− 278
# Labs 1 1

Mean −− 23.82 −− 36.37 −− 57.53
SD
CV
1 −−
−−
0.732
3.1
2 −−
−−
1.45
4.0
3 −−
−−
2.43
4.2
# Points −− 460 −− 896 −− 673
# Labs 4 5 5
Mean −− 26.44 −− 38.21 −− 56.50
SD
CV
1 −−
−−
2.46
9.3
2 −−
−−
2.55
6.7
3 −−
−−
2.03
3.6
# Points −− 451 −− 458 −− 474
# Labs 3 3 3
Method Group • Direct measure, immunoinhibition

Mean 26.44 27.85 38.47 41.55 65.22 66.02
SD
CV
1 3.35
12.7
2.71
9.7
2 5.29
13.8
2.90
7.0
3 2.27
3.5
4.09
6.2
# Points 502 33274 463 45718 314 49686
# Labs 12 74 12 96 9 99
Cholesterol, HDL Direct measure, polymer−polyanion mg/dL

Mean 30.15 30.36 41.85 42.34 62.65 65.41
SD
CV
1 1.33
4.4
1.42
4.7
2 1.84
4.4
1.93
4.6
3 3.46
5.5
2.97
4.5
# Points 1588 53357 1092 28741 887 50713
# Labs 57 184 44 122 31 143
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c Ultra HDL, REF 07P75
Mean −− 31.15 −− 44.53 −− −−
SD
CV
1 −−
−−
11.95
38.4
2 −−
−−
20.72
46.5
3 −−
−−
−−
−−
# Points −− 83 −− 81 −− −−
# Labs 1 1

Mean 30.90 30.49 43.87 43.73 68.24 68.08
SD
CV
1 0.708
2.3
0.641
2.1
2
0.623
1.4
0.778
1.8
3 1.01
1.5
1.35
2.0
# Points 74 1264 74 1151 74 1262
# Labs 2 2 2 2 2 2

Mean 29.15 29.79 42.29 42.97 65.71 68.55
SD
CV
1 1.53
5.2
1.75
5.9
2 1.63
3.9
1.82
4.2
3 3.24
4.9
3.14
4.6
# Points 339 17727 207 11633 192 16648
# Labs 12 53 8 29 7 46

Mean −− −− −− 38.43 −− 58.60
SD
CV
1 −−
−−
−−
−−
2−−
−−
1.19
3.1
3 −−
−−
1.99
3.4
# Points −− −− −− 316 −− 316
# Labs 2 2

Mean −− 30.30 −− 42.90 −− 68.36
SD
CV
1 −−
−−
1.42
4.7
−−
−−
2 1.52
3.5
3 −−
−−
3.34
4.9
# Points −− 1400 −− 1091 −− 2384
# Labs 2 6 8

Mean 29.64 29.99 41.60 42.47 68.28 68.02
SD
CV
1 1.78
6.0
1.41
4.7
2.68
6.4
2 2.31
5.4
3 5.83
8.5
3.19
4.7
# Points 1289 30219 1051 11305 449 26314
# Labs 41 107 33 61 14 79

Mean −− 27.09 −− 38.61 −− 60.08
SD
CV
1 −−
−−
0.962
3.6
2 −−
−−
1.45
3.7
3 −−
−−
1.87
3.1
# Points −− 215 −− 215 −− 214
# Labs 1 1 1

Mean 24.17 24.47 33.45 33.43 46.40 45.61
SD
CV
1 0.791
3.3
1.32
5.4
2 0.791
2.4
1.75
5.2
3 1.41
3.0
2.68
5.9
# Points 62 656 62 656 62 656
# Labs 2 2 2 2 2 2
Beckman Coulter AU Series • Sekisui Pureauto

Mean −− 28.67 −− 41.81 −− 66.26
SD
CV
1 −−
−−
0.741
2.6
2 −−
−−
0.984
2.4
3 −−
−−
1.69
2.6
# Points −− 2110 −− 1993 −− 1981
# Labs 2 2 2

Beckman Coulter Couphonics • Beckman Coulter AU HDL, OSR6X95
Mean −− 29.71 −− 42.16 −− 67.31
SD
CV
1 −−
−−
1.15
3.9
−−
−−
2 1.79
4.2
3 −−
−−
2.82
4.2
# Points −− 193 −− 196 −− 196
# Labs 1 1 1

Mean −− 29.53 −− 41.71 −− 67.09
SD
CV
1 −−
−−
1.33
4.5
2 −−
−−
1.92
4.6
3 −−
−−
3.10
4.6
# Points −− 1847 −− 665 −− 1796
# Labs 12 3 10
Beckman Coulter UniCel DxC Series • BC DxC HDL, REF A15625

Mean 29.70 29.04 −− 45.87 64.80 69.02
SD
CV
1 0.980
3.3
1.44
5.0
−−
−−
2 2.64
5.8
3 1.41
2.2
5.58
8.1
# Points 25 4030 −− 1462 30 4080
# Labs 1 9 3 1 9
Beckman Coulter UniCel DxC Series • BC DxC HDLD, REF 650207

Mean −− 29.62 −− 47.15 −− 68.23
SD
CV
1 −−
−−
1.52
5.1
−−
−−
2 5.21
11.0
3 −−
−−
3.25
4.8
# Points −− 1083 −− 447 −− 1246
# Labs 4 3 5

Mean 21.70 22.60 31.30 32.91 −− −−
SD
CV
1 0.483
2.2
1.37
6.1
2 0.675
2.2
2.89
8.8
3 −−
−−
−−
−−
# Points 10 251 10 184 −− −−
# Labs 1 1 1 1

Mean −− −− −− 35.33 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.848
2.4
3 −−
−−
−−
−−
# Points −− −− −− 42 −− −−
# Labs 2

Mean −− −− −− 33.69 −− 53.70
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.615
1.8
3 −−
−−
1.16
2.2
# Points −− −− −− 58 −− 57
# Labs 1 1

Mean −− 29.14 −− −− −− 66.04
SD
CV
1 −−
−−
1.51
5.2
2 −−
−−
−−
−−
3 −−
−−
2.46
3.7
# Points −− 28 −− −− −− 28
# Labs 1 1
Mindray BS Series
Mean 22.43 24.03 32.48 36.00 −− 54.94
SD
CV
1 1.16
5.2
1.50
6.2
2 1.16
3.6
1.66
4.6
3 −−
−−
2.14
3.9
# Points 21 245 21 441 −− 343
# Labs 1 2 1 2 2

Mean −− −− −− 33.24 −− 47.47
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.707
2.1
3 −−
−−
0.818
1.7
# Points −− −− −− 148 −− 148
# Labs 1 1

RANDOX RX daytona
Mean 25.89 24.23 36.94 34.90 66.60 66.60
SD
CV
1 2.00
7.7
2.97
12.3
2 3.69
10.0
4.16
11.9
3 0.000
0.0
0.000
0.0
# Points 20 92 16 124 1 1
# Labs 1 1 1 1 1 1
RANDOX RX imola
Mean 21.72 24.55 32.98 36.75 −− −−
SD
CV
1 1.20
5.5
3.32
13.5
2 0.977
3.0
5.56
15.1
3 −−
−−
−−
−−
# Points 26 224 24 196 −− −−
# Labs 1 1 1 1

Mean 21.85 21.90 −− 30.90 38.97 42.84
SD
CV
1 0.359
1.6
1.36
6.2
2 −−
−−
0.549
1.8
3 0.707
1.8
3.97
9.3
# Points 34 660 −− 126 35 652
# Labs 1 4 1 1 4
Roche cobas 6000/c 311 • 4th Generation

Mean −− 22.55 −− 31.09 −− 44.36
SD
CV
1 −−
−−
0.797
3.5
2 −−
−−
1.20
3.8
3 −−
−−
1.77
4.0
# Points −− 317 −− 325 −− 316
# Labs 2 2 2

Mean 22.31 22.33 29.60 30.64 42.42 43.81
SD
CV
1 0.882
4.0
1.09
4.9
2 1.71
5.8
1.79
5.8
3 2.50
5.9
3.00
6.9
# Points 622 17046 120 6220 566 17685
# Labs 14 52 5 21 13 53
Roche cobas 8000

Mean −− 21.78 −− −− −− 44.52
SD
CV
1 −−
−−
0.802
3.7
2 −−
−−
−−
−−
3 −−
−−
1.41
3.2
# Points −− 501 −− −− −− 496
# Labs 1 1

Mean 22.02 21.73 28.23 30.13 42.32 43.62
SD
CV
1 0.549
2.5
0.775
3.6
2 1.16
4.1
1.74
5.8
3 1.30
3.1
1.75
4.0
# Points 1331 34043 66 5830 1377 34602
# Labs 17 41 1 17 17 43
Roche cobas 8000 • Sekisui Nanopia

Mean −− −− −− 41.20 −− 66.08
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.782
1.9
3 −−
−−
1.41
2.1
# Points −− −− −− 403 −− 268
# Labs 2 2

Mean −− 20.30 −− 28.89 −− −−
SD
CV
1 −−
−−
0.381
1.9
2 −−
−−
0.468
1.6
3 −−
−−
−−
−−
# Points −− 12 −− 12 −− −−
# Labs 1 1
Roche cobas c 303/503 • Roche HDLC4

Mean 21.63 21.87 29.89 30.17 41.30 42.92
SD
CV
1 0.917
4.2
0.898
4.1
2 1.15
3.9
1.21
4.0
3 1.76
4.3
2.23
5.2
# Points 112 3132 92 2838 106 2413
# Labs 4 9 3 8 4 8

Roche cobas c 303/503 • Roche HDLC4. REF 08057877
Mean 21.34 21.52 28.04 30.15 40.84 41.89
SD
CV
1 0.830
3.9
1.01
4.7
2 0.344
1.2
0.939
3.1
3 1.22
3.0
2.26
5.4
# Points 157 8881 20 2889 138 9666
# Labs 6 32 1 8 5 31

Mean 20.88 21.03 28.62 29.49 41.38 41.84
SD
CV
1 0.387
1.9
0.905
4.3
2 0.773
2.7
1.17
4.0
3 0.773
1.9
2.02
4.8
# Points 13 266 13 266 13 266
# Labs 1 1 1 1 1 1
Roche cobas Integra / c 111 • Roche HDLC4

Mean 22.63 22.24 32.00 31.37 44.88 44.83
SD
CV
1 1.10
4.9
0.894
4.0
2 1.00
3.1
1.09
3.5
3 1.77
3.9
1.73
3.9
# Points 51 1374 32 776 51 1380
# Labs 2 3 1 1 2 3

Mean −− 24.17 −− 38.54 −− 61.52
SD
CV
1 −−
−−
0.774
3.2
2 −−
−−
0.855
2.2
3 −−
−−
1.34
2.2
# Points −− 551 −− 478 −− 597
# Labs 2 2 2

Mean −− −− −− 40.86 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.93
4.7
3 −−
−−
−−
−−
# Points −− −− −− 24 −− −−
# Labs 1

Mean 23.78 23.80 33.47 36.32 53.45 56.99
SD
CV
1 0.888
3.7
0.880
3.7
2 0.640
1.9
1.38
3.8
3 1.78
3.3
1.98
3.5
# Points 80 14539 15 10415 80 14247
# Labs 3 32 1 27 3 35

Mean 24.48 23.53 37.29 35.54 64.97 58.36
SD
CV
1 3.02
12.3
1.15
4.9
2 3.42
9.2
1.80
5.1
3 1.55
2.4
2.64
4.5
# Points 299 16935 302 9978 30 11117
# Labs 8 70 8 45 1 54
Siemens Atellica CH Analyzer • Alternate Formulation/Standardization

Mean −− 30.15 −− −− −− 70.57
SD
CV
1 −−
−−
0.470
1.6
2
−−
−−
−−
−−
3 −−
−−
1.42
2.0
# Points −− 113 −− −− −− 113
# Labs 2 2
Siemens Atellica CH Analyzer • Siemens Atellica CH HDLC , REF 11537213

Mean 30.26 26.43 42.35 40.54 67.64 63.01
SD
CV
1 0.619
2.0
3.22
12.2
2
0.993
2.3
3.38
8.3
3 2.61
3.9
5.33
8.5
# Points 118 4693 61 747 127 4627
# Labs 4 14 3 5 5 15
Siemens Atellica CH Analyzer • Siemens Atellica CH LDLC, REF 11537214

Mean −− 28.57 −− −− −− 66.09
SD
CV
1 −−
−−
0.545
1.9
2
−−
−−
−−
−−
3 −−
−−
1.99
3.0
# Points −− 30 −− −− −− 34
# Labs 1 1

Mean −− 34.44 −− 49.86 −− 77.33
SD
CV
1 −−
−−
1.22
3.5
2 −−
−−
1.81
3.6
3 −−
−−
2.84
3.7
# Points −− 105 −− 105 −− 105
# Labs 1 1 1
Toshiba−TBA
Mean −− −− −− −− −− 59.25
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
1.96
3.3
# Points −− −− −− −− −− 81
# Labs 1
Method Group • Direct measure, polymer−polyanion

Mean 26.50 26.52 39.76 38.80 52.18 57.86
SD
CV
1 4.02
15.2
4.04
15.2
2 4.69
11.8
5.31
13.7
3 11.67
22.4
11.00
19.0
# Points 6271 218K 3278 102K 4218 207K
# Labs 179 651 117 386 110 570
Cholesterol, HDL Direct measure, polymer−polyanion−Samsung mg/dL

Mean −− 28.29 −− 40.97 −− 64.28
SD
CV
1 −−
−−
1.06
3.8
2 −−
−−
1.55
3.8
3 −−
−−
2.21
3.4
# Points −− 64 −− 59 −− 57
# Labs 2 2 2
Method Group • Direct measure, polymer−polyanion−Samsung

Mean −− 28.29 −− 40.97 −− 64.28
SD
CV
1 −−
−−
1.06
3.8
−−
−−
2 1.55
3.8
3 −−
−−
2.21
3.4
# Points −− 64 −− 59 −− 57
# Labs 2 2 2
Cholesterol, HDL Direct measure, PTA/MgCl2−VITROS mg/dL

Mean 21.20 21.19 −− 34.74 53.40 57.09
SD
CV
1 0.700
3.3
0.935
4.4
2 −−
−−
1.77
5.1
3 1.60
3.0
2.84
5.0
# Points 16 1016 −− 92 16 981
# Labs 1 9 3 1 7

Mean −− 20.43 −− −− −− 57.19
SD
CV
1 −−
−−
0.953
4.7
2 −−
−−
−−
−−
3 −−
−−
3.09
5.4
# Points −− 23 −− −− −− 24
# Labs 1 2

Mean −− 4.78 −− −− −− −−
SD
CV
1 −−
−−
0.206
4.3
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 4 −− −− −− −−
# Labs 1

Mean 21.52 20.54 33.93 33.01 −− −−
SD
CV
1 0.577
2.7
0.961
4.7
2 1.14
3.4
1.61
4.9
3 −−
−−
−−
−−
# Points 54 409 54 404 −− −−
# Labs 2 2 2 2

Mean −− 18.45 −− −− −− 64.33
SD
CV
1 −−
−−
0.953
5.2
2 −−
−−
−−
−−
3 −−
−−
2.30
3.6
# Points −− 97 −− −− −− 100
# Labs 1 1

Mean −− 0.000 −− 0.000 −− 0.000
SD
CV
1 −−
−−
0.000
−−
2 −−
−−
0.000
−−
3 −−
−−
0.000
−−
# Points −− 0 −− 0 −− 0
# Labs 1 1 1

Mean −− 19.62 −− −− −− 32.23
SD
CV
1 −−
−−
0.603
3.1
2 −−
−−
−−
−−
3 −−
−−
31.60
98.0
# Points −− 62 −− −− −− 30
# Labs 3 3

Mean −− 23.10 −− −− −− 58.79
SD
CV
1 −−
−−
1.01
4.4
2 −−
−−
−−
−−
3 −−
−−
2.40
4.1
# Points −− 253 −− −− −− 213
# Labs 1 1

Mean −− 20.49 −− 34.44 −− 58.13
SD
CV
1 −−
−−
1.67
8.2
2 −−
−−
2.03
5.9
3 −−
−−
3.92
6.7
# Points −− 453 −− 37 −− 459
# Labs 13 3 12

Mean −− 21.54 −− 35.48 −− 59.02
SD
CV
1 −−
−−
1.31
6.1
2 −−
−−
1.73
4.9
3 −−
−−
3.14
5.3
# Points −− 1367 −− 958 −− 1015
# Labs 7 5 6

Mean −− 21.33 −− −− −− 60.81
SD
CV
1 −−
−−
1.40
6.6
2 −−
−−
−−
−−
3 −−
−−
6.22
10.2
# Points −− 369 −− −− −− 446
# Labs 5 5

Mean −− 20.66 −− 33.05 −− 56.40
SD
CV
1 −−
−−
1.45
7.0
2 −−
−−
1.86
5.6
3 −−
−−
3.48
6.2
# Points −− 3763 −− 1177 −− 3551
# Labs 36 16 36

Mean −− 21.50 −− 35.82 −− 57.74
SD
CV
1 −−
−−
1.42
6.6
2 −−
−−
1.90
5.3
3 −−
−−
3.88
6.7
# Points −− 2800 −− 831 −− 2844
# Labs 31 16 31

Mean −− 22.09 −− 36.15 −− 59.15
SD
CV
1 −−
−−
1.26
5.7
2 −−
−−
1.67
4.6
3 −−
−−
2.65
4.5
# Points −− 6904 −− 3651 −− 7037
# Labs 61 29 60

Mean −− 20.16 −− 34.39 −− 56.19
SD
CV
1 −−
−−
1.17
5.8
2 −−
−−
1.54
4.5
3 −−
−−
2.56
4.6
# Points −− 838 −− 169 −− 842
# Labs 7 2 7

Mean −− 21.88 −− 35.02 −− 57.56
SD
CV
1 −−
−−
1.34
6.1
2 −−
−−
1.88
5.4
3 −−
−−
3.06
5.3
# Points −− 8703 −− 3568 −− 8604
# Labs 64 30 63

Mean −− 23.24 −− 37.49 −− 57.98
SD
CV
1 −−
−−
1.53
6.6
2 −−
−−
1.97
5.3
3 −−
−−
3.41
5.9
# Points −− 3604 −− 1057 −− 3011
# Labs 35 14 34

Mean 20.82 21.77 −− 36.00 53.98 57.60
SD
CV
1 1.08
5.2
1.42
6.5
2 −−
−−
1.91
5.3
3 2.03
3.8
3.42
5.9
# Points 63 5036 −− 1925 63 4683
# Labs 2 40 15 2 38

Mean 21.35 21.57 34.32 34.69 −− 55.94
SD
CV
1 1.14
5.4
1.26
5.8
2 1.58
4.6
1.80
5.2
3 −−
−−
2.98
5.3
# Points 20 1167 19 176 −− 943
# Labs 1 13 1 2 8

Mean 20.84 21.14 33.88 34.20 52.46 56.14
SD
CV
1 1.10
5.3
1.08
5.1
2 1.35
4.0
1.53
4.5
3 3.12
5.9
3.11
5.5
# Points 405 5549 127 2396 344 4820
# Labs 19 58 7 29 16 49

Mean 20.76 21.21 31.57 34.04 55.87 55.42
SD
CV
1 1.48
7.1
1.23
5.8
2 0.841
2.7
1.86
5.5
3 2.48
4.4
3.21
5.8
# Points 54 3356 32 1552 21 3043
# Labs 4 40 2 19 2 36

Mean 21.78 21.56 34.60 34.29 54.08 55.77
SD
CV
1 1.35
6.2
1.27
5.9
2 1.52
4.4
1.78
5.2
3 3.57
6.6
3.02
5.4
# Points 297 2573 80 646 287 2088
# Labs 18 35 7 16 17 32

Mean 21.95 21.87 34.77 34.76 56.42 56.11
SD
CV
1 1.37
6.2
1.22
5.6
2 1.19
3.4
1.26
3.6
3 2.71
4.8
2.73
4.9
# Points 252 445 170 305 198 373
# Labs 15 17 8 9 13 15

Mean 20.73 28.61 32.78 38.08 53.60 70.99
SD
CV
1 1.19
5.7
24.30
84.9
2 1.65
5.0
26.20
68.8
3 3.92
7.3
55.73
78.5
# Points 56 687 76 663 71 659
# Labs 4 4 4 4 3 3

Method Group • Direct measure, PTA/MgCl2−VITROS
Mean 21.33 21.74 33.99 35.26 53.97 57.60
SD
CV
1 1.32
6.2
3.33
15.3
2 1.60
4.7
5.23
14.8
3 3.46
6.4
7.67
13.3
# Points 1217 49219 558 19858 1000 45800
# Labs 66 483 31 218 54 451
Cholesterol, HDL Direct measure−PEG mg/dL

Mean 28.62 29.42 39.83 41.85 61.87 63.76
SD
CV
1 0.773
2.7
1.32
4.5
2 0.773
1.9
1.86
4.4
3 1.55
2.5
2.51
3.9
# Points 38 617 38 619 38 619
# Labs 1 1 1 2 1 2
Beckman Coulter AU Series • Sekisui Diagnostics SEKURE

Mean −− 28.40 −− −− −− 62.53
SD
CV
1 −−
−−
1.02
3.6
2 −−
−−
−−
−−
3 −−
−−
1.93
3.1
# Points −− 1376 −− −− −− 1372
# Labs 3 3

Mean −− 28.82 −− −− −− 66.42
SD
CV
1 −−
−−
1.01
3.5
2 −−
−−
−−
−−
3 −−
−−
2.17
3.3
# Points −− 1056 −− −− −− 1046
# Labs 2 2

Mean −− 27.96 −− −− −− 64.24
SD
CV
1 −−
−−
1.56
5.6
2 −−
−−
−−
−−
3 −−
−−
2.93
4.6
# Points −− 397 −− −− −− 400
# Labs 2 2
ILab Series
Mean 26.18 26.42 42.00 42.70 −− −−
SD
CV
1 1.33
5.1
1.48
5.6
2 1.55
3.7
2.20
5.1
3 −−
−−
−−
−−
# Points 11 43 11 43 −− −−
# Labs 1 1 1 1
Mindray BS Series
Mean −− 25.15 −− 51.69 −− −−
SD
CV
1 −−
−−
0.963
3.8
2 −−
−−
1.94
3.7
3 −−
−−
−−
−−
# Points −− 224 −− 225 −− −−
# Labs 1 1

Mean 21.28 22.57 31.20 30.42 42.04 44.79
SD
CV
1 0.976
4.6
0.902
4.0
2 0.531
1.7
1.48
4.9
3 2.05
4.9
2.21
4.9
# Points 275 4587 35 3360 278 4990
# Labs 2 12 1 11 2 18

Mean 21.36 22.95 −− 31.95 41.21 45.12
SD
CV
1 0.731
3.4
1.05
4.6
2 −−
−−
1.41
4.4
3 1.59
3.9
2.40
5.3
# Points 61 3488 −− 2447 61 3439
# Labs 2 10 6 2 10
Roche cobas 8000

Mean 22.81 21.86 −− 29.87 40.44 43.05
SD
CV
1 0.517
2.3
0.705
3.2
2 −−
−−
1.42
4.8
3 0.714
1.8
2.13
4.9
# Points 54 5940 −− 4480 55 7791
# Labs 1 10 8 1 15
Cholesterol, HDL Direct measure−PEG mg/dL

Mean −− 21.61 −− 34.22 −− 44.62
SD
CV
1 −−
−−
0.535
2.5
2 −−
−−
3.09
9.0
3 −−
−−
3.82
8.6
# Points −− 342 −− 54 −− 343
# Labs 1 1 2

Mean −− 21.81 −− −− −− 45.46
SD
CV
1 −−
−−
0.967
4.4
2 −−
−−
−−
−−
3 −−
−−
1.45
3.2
# Points −− 1077 −− −− −− 849
# Labs 4 2

Mean −− 22.43 −− 31.09 −− 44.24
SD
CV
1 −−
−−
0.830
3.7
2 −−
−−
0.839
2.7
3 −−
−−
1.51
3.4
# Points −− 2349 −− 2662 −− 2251
# Labs 7 7 7

Mean −− 21.47 −− −− −− 43.38
SD
CV
1 −−
−−
0.546
2.5
2 −−
−−
−−
−−
3 −−
−−
1.19
2.7
# Points −− 86 −− −− −− 86
# Labs 1 1

Mean −− 22.20 −− 30.39 −− 43.38
SD
CV
1 −−
−−
0.514
2.3
2 −−
−−
0.780
2.6
3 −−
−−
1.89
4.4
# Points −− 1393 −− 1354 −− 1417
# Labs 3 2 3

Mean 25.91 27.26 39.44 39.89 66.13 65.07
SD
CV
1 0.387
1.5
1.04
3.8
2 0.773
2.0
0.809
2.0
3 1.55
2.3
2.42
3.7
# Points 31 345 31 345 31 345
# Labs 1 1 1 1 1 1
Mean −− −− −− 35.83 −− 46.95
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.25
3.5
3 −−
−−
2.53
5.4
# Points −− −− −− 314 −− 310
# Labs 1 1

Mean 28.90 28.51 38.48 38.80 53.41 56.49
SD
CV
1 0.857
3.0
1.58
5.5
2 1.47
3.8
1.46
3.8
3 2.83
5.3
2.92
5.2
# Points 1035 68133 167 9743 1055 63598
# Labs 34 184 6 47 33 157

Mean 25.33 26.22 34.79 36.70 50.75 54.09
SD
CV
1 1.10
4.3
1.28
4.9
2 1.76
5.1
1.69
4.6
3 2.43
4.8
2.66
4.9
# Points 2514 199K 451 46645 2311 193K
# Labs 73 425 16 114 72 409
Method Group • Direct measure−PEG

Mean 25.92 26.53 36.02 35.88 50.78 54.01
SD
CV
1 2.35
9.1
2.00
7.5
2 2.78
7.7
3.29
9.2
3 4.44
8.8
4.19
7.8
# Points 4019 291K 733 72291 3829 282K
# Labs 115 669 26 202 112 637
Cholesterol, HDL Polyethylene glycol (PEG) mg/dL

1drop
Mean −− 25.53 −− 36.21 −− −−
SD
CV
1 −−
−−
1.05
4.1
2 −−
−−
1.81
5.0
3 −−
−−
−−
−−
# Points −− 58 −− 58 −− −−
# Labs 1 1
Abbott ARCHITECT/Alinity (c, i, ci models) • 10 mL vial

Mean 22.43 23.97 40.22 40.05 68.06 66.38
SD
CV
1 1.16
5.2
1.37
5.7
2 1.16
2.9
1.24
3.1
3 2.71
4.0
2.42
3.6
# Points 27 322 26 365 27 359
# Labs 1 1 1 1 1 1
ERBA XL−640
Mean −− 25.42 −− 35.09 −− −−
SD
CV
1 −−
−−
1.31
5.2
2 −−
−−
2.34
6.7
3 −−
−−
−−
−−
# Points −− 13 −− 13 −− −−
# Labs 1 1

Mean 24.42 24.42 35.36 35.36 −− −−
SD
CV
1 0.589
2.4
0.589
2.4
2 0.353
1.0
0.353
1.0
3 −−
−−
−−
−−
# Points 4 4 4 4 −− −−
# Labs 1 1 1 1
Method Group • Polyethylene glycol (PEG)

Mean 22.69 24.25 39.57 39.36 68.06 66.38
SD
CV
1 1.29
5.7
1.44
5.9
2 2.00
5.1
2.06
5.2
3 2.71
4.0
2.42
3.6
# Points 31 397 30 440 27 359
# Labs 2 4 2 4 1 1
Cholesterol, HDL Ultracentrifugation/Fluorescence mg/dL

Mean −− 26.07 −− 38.78 −− 61.67
SD
CV
1 −−
−−
3.21
12.3
2 −−
−−
3.88
10.0
3 −−
−−
5.22
8.5
# Points −− 1471 −− 1486 −− 1459
# Labs 2 2 2
Method Group • Ultracentrifugation/Fluorescence

Mean −− 26.07 −− 38.78 −− 61.67
SD
CV
1 −−
−−
3.21
12.3
2 −−
−−
3.88
10.0
3 −−
−−
5.22
8.5
# Points −− 1471 −− 1486 −− 1459
# Labs 2 2 2
Cholesterol, LDL Agarose Gel mg/dL

Mean −− 52.90 −− −− −− 136.8
SD
CV
1 −−
−−
3.36
6.4
2 −−
−−
−−
−−
3 −−
−−
7.51
5.5
# Points −− 94 −− −− −− 94
# Labs 1 1

Mean −− 62.80 −− −− −− 167.1
SD
CV
1 −−
−−
2.33
3.7
2 −−
−−
−−
−−
3 −−
−−
4.67
2.8
# Points −− 273 −− −− −− 273
# Labs 1 1
Cholesterol, LDL Agarose Gel mg/dL

Mean −− 60.27 −− −− −− 159.3
SD
CV
1 −−
−−
5.07
8.4
2 −−
−−
−−
−−
3 −−
−−
14.34
9.0
# Points −− 367 −− −− −− 367
# Labs 2 2
Cholesterol, LDL Calculated mg/dL

Mean −− 65.60 −− 104.6 −− 157.7
SD
CV
1 −−
−−
1.99
3.0
2 −−
−−
3.36
3.2
3 −−
−−
5.28
3.3
# Points −− 181 −− 181 −− 181
# Labs 1 1 1

Mean 66.75 61.66 120.0 120.0 180.8 180.8
SD
CV
1 0.957
1.4
2.38
3.9
2 2.16
1.8
2.16
1.8
3 3.20
1.8
3.20
1.8
# Points 4 27 4 4 4 4
# Labs 1 2 1 1 1 1

Mean −− 66.46 −− −− −− 174.2
SD
CV
1 −−
−−
2.52
3.8
2 −−
−−
−−
−−
3 −−
−−
5.79
3.3
# Points −− 422 −− −− −− 418
# Labs 2 2

Mean −− 64.06 −− −− −− 176.6
SD
CV
1 −−
−−
1.54
2.4
2 −−
−−
−−
−−
3 −−
−−
4.70
2.7
# Points −− 30 −− −− −− 29
# Labs 1 1

Mean −− 64.40 −− 100.2 −− −−
SD
CV
1 −−
−−
1.02
1.6
2 −−
−−
1.73
1.7
3 −−
−−
−−
−−
# Points −− 66 −− 65 −− −−
# Labs 1 1

Mean −− 67.91 −− 99.94 −− −−
SD
CV
1 −−
−−
1.12
1.6
2 −−
−−
1.58
1.6
3 −−
−−
−−
−−
# Points −− 47 −− 48 −− −−
# Labs 1 1

Mean −− 65.15 −− 119.0 −− 176.8
SD
CV
1 −−
−−
1.70
2.6
2 −−
−−
1.98
1.7
3 −−
−−
0.000
0.0
# Points −− 86 −− 44 −− 1
# Labs 3 1 1

Mean −− 62.51 −− 101.7 −− 154.2
SD
CV
1 −−
−−
2.33
3.7
2 −−
−−
0.370
0.4
3 −−
−−
4.93
3.2
# Points −− 606 −− 3 −− 616
# Labs 2 1 2

Mean 66.75 64.46 120.0 104.9 180.8 162.0
SD
CV
1 0.957
1.4
2.89
4.5
2 2.16
1.8
6.51
6.2
3 3.20
1.8
10.79
6.7
# Points 4 1479 4 360 4 1249
# Labs 1 13 1 6 1 8
Cholesterol, LDL Dextran sulfate 50K mg/dL

Mean −− 67.83 −− −− −− 176.0
SD
CV
1 −−
−−
1.09
1.6
2 −−
−−
−−
−−
3 −−
−−
3.05
1.7
# Points −− 443 −− −− −− 437
# Labs 1 1

Mean −− −− −− 111.7 −− 181.0
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.57
2.3
3 −−
−−
4.28
2.4
# Points −− −− −− 325 −− 325
# Labs 1 1
Method Group • Dextran sulfate 50K

Mean −− 67.83 −− 111.7 −− 178.2
SD
CV
1 −−
−−
1.09
1.6
2 −−
−−
2.57
2.3
3 −−
−−
4.38
2.5
# Points −− 443 −− 325 −− 762
# Labs 1 1 2
Cholesterol, LDL Direct measure mg/dL

Mean 66.81 66.27 110.6 110.6 169.3 168.6
SD
CV
1 2.67
4.0
2.65
4.0
2 5.14
4.6
4.78
4.3
3 6.04
3.6
6.56
3.9
# Points 975 27123 751 17087 536 25057
# Labs 41 118 34 84 22 90
Abbott ARCHITECT/Alinity (c, i, ci models) • 10 mL vial

Mean 64.19 63.07 112.1 112.8 174.8 179.3
SD
CV
1 1.16
1.8
1.61
2.5
2 1.16
1.0
2.21
2.0
3 3.48
2.0
7.20
4.0
# Points 25 299 25 370 25 398
# Labs 1 1 1 1 1 1
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c Direct LDL, REF 07P71
Mean −− 64.87 −− −− −− 168.0
SD
CV
1 −−
−−
2.34
3.6
2−−
−−
−−
−−
3 −−
−−
5.00
3.0
# Points −− 224 −− −− −− 220
# Labs 1 1

Mean 61.87 62.84 102.1 104.0 155.1 158.3
SD
CV
1 1.15
1.9
1.14
1.8
2
1.74
1.7
1.83
1.8
3 2.51
1.6
2.77
1.7
# Points 55 1219 64 1114 50 1212
# Labs 2 2 2 2 2 2

Mean 61.29 64.31 103.7 110.5 143.2 167.0
SD
CV
1 4.22
6.9
5.50
8.6
2 5.63
5.4
11.26
10.2
3 9.96
7.0
16.63
10.0
# Points 281 11859 233 10762 75 12950
# Labs 9 44 9 36 4 45

Mean −− −− 120.4 118.6 176.6 176.2
SD
CV
1 −−
−−
−−
−−
1.58
1.3
2 4.36
3.7
3 2.04
1.2
4.30
2.4
# Points −− −− 87 1186 87 1189
# Labs 2 4 2 4

Mean −− 69.53 −− 119.5 −− 177.8
SD
CV
1 −−
−−
2.65
3.8
2 −−
−−
4.30
3.6
3 −−
−−
5.95
3.3
# Points −− 580 −− 589 −− 583
# Labs 4 4 4

Beckman Coulter AU Series • Beckman Coulter AU LDL, OSR6X83
Mean 71.91 71.62 124.5 122.1 180.2 180.4
SD
CV
1 2.20
3.1
2.82
3.9
2
3.12
2.5
6.49
5.3
3 12.11
6.7
11.17
6.2
# Points 203 7217 172 9077 261 10787
# Labs 5 25 3 27 7 30
Beckman Coulter AU Series • Beckman Coulter AU LDL, OSR6X96

Mean 59.86 59.54 99.39 96.32 149.2 146.7
SD
CV
1 2.62
4.4
2.89
4.8
2
4.30
4.3
5.30
5.5
3 6.75
4.5
7.26
4.9
# Points 1114 26130 923 26277 410 36913
# Labs 39 99 33 84 13 92

Mean −− 59.93 −− 101.2 −− 162.6
SD
CV
1 −−
−−
4.37
7.3
2 −−
−−
7.79
7.7
3 −−
−−
11.24
6.9
# Points −− 215 −− 215 −− 214
# Labs 1 1 1

Mean −− 71.00 −− 123.9 −− 199.1
SD
CV
1 −−
−−
1.81
2.5
2 −−
−−
2.62
2.1
3 −−
−−
4.58
2.3
# Points −− 592 −− 592 −− 592
# Labs 2 2 2
Beckman Coulter AU Series • Randox

Mean −− 70.84 −− 121.6 −− 192.2
SD
CV
1 −−
−−
1.37
1.9
2 −−
−−
3.22
2.6
3 −−
−−
4.41
2.3
# Points −− 9 −− 9 −− 9
# Labs 1 1 1
Beckman Coulter AU Series • Roche 2nd generation LDL_C

Mean −− 71.86 −− 121.1 −− 192.1
SD
CV
1 −−
−−
1.70
2.4
2 −−
−−
3.05
2.5
3 −−
−−
4.10
2.1
# Points −− 89 −− 89 −− 88
# Labs 1 1 1

Mean −− 66.05 −− −− −− 168.3
SD
CV
1 −−
−−
1.63
2.5
2 −−
−−
−−
−−
3 −−
−−
4.22
2.5
# Points −− 1243 −− −− −− 1275
# Labs 3 3
Beckman Coulter AU Series • Sekisui Pureauto

Mean −− 63.99 −− 107.4 −− 164.0
SD
CV
1 −−
−−
1.49
2.3
2 −−
−−
2.49
2.3
3 −−
−−
3.69
2.2
# Points −− 2087 −− 1995 −− 1976
# Labs 2 2 2

Mean −− 72.10 −− −− −− 196.3
SD
CV
1 −−
−−
1.86
2.6
2 −−
−−
−−
−−
3 −−
−−
5.09
2.6
# Points −− 721 −− −− −− 721
# Labs 1 1

Mean −− 60.00 −− 98.01 −− 151.9
SD
CV
1 −−
−−
2.94
4.9
2 −−
−−
3.30
3.4
3 −−
−−
7.84
5.2
# Points −− 5565 −− 2103 −− 5161
# Labs 18 7 14

Mean −− −− −− 104.7 −− 165.5
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.50
1.4
3 −−
−−
2.32
1.4
# Points −− −− −− 165 −− 165
# Labs 1 1
Dirui CS Series
Mean −− 61.15 −− 102.0 −− 154.7
SD
CV
1 −−
−−
3.66
6.0
2 −−
−−
5.37
5.3
3 −−
−−
8.02
5.2
# Points −− 871 −− 862 −− 844
# Labs 2 2 2

Mean −− 62.91 −− 117.4 −− 159.8
SD
CV
1 −−
−−
1.78
2.8
2 −−
−−
4.87
4.1
3 −−
−−
4.76
3.0
# Points −− 1644 −− 122 −− 1646
# Labs 5 2 5

Mean −− −− −− 127.2 −− 209.7
SD
CV
1 −−
−−
−−
−−
2
−−
−−
2.84
2.2
3 −−
−−
3.22
1.5
# Points −− −− −− 54 −− 54
# Labs 1 1

Mean −− 65.70 −− −− −− −−
SD
CV
1 −−
−−
0.750
1.1
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 69 −− −− −− −−
# Labs 1

Mean −− 64.31 −− −− −− 180.4
SD
CV
1 −−
−−
2.46
3.8
2 −−
−−
−−
−−
3 −−
−−
7.57
4.2
# Points −− 88 −− −− −− 90
# Labs 1 1

Mean −− 63.63 −− −− −− 159.6
SD
CV
1 −−
−−
1.45
2.3
2 −−
−−
−−
−−
3 −−
−−
3.73
2.3
# Points −− 398 −− −− −− 397
# Labs 2 2
Mindray BS Series
Mean 72.31 71.32 121.0 119.4 186.4 182.4
SD
CV
1 1.16
1.6
2.62
3.7
2 1.93
1.6
4.54
3.8
3 4.25
2.3
7.24
4.0
# Points 21 468 21 496 21 496
# Labs 1 3 1 2 1 2

Mean −− −− −− 106.8 −− 165.5
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.44
1.3
3 −−
−−
2.32
1.4
# Points −− −− −− 147 −− 147
# Labs 1 1

Mean −− −− −− 123.6 −− 190.0
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.83
1.5
3 −−
−−
3.19
1.7
# Points −− −− −− 85 −− 87
# Labs 1 1

RANDOX RX daytona
Mean 74.30 77.36 163.2 136.2 209.3 193.7
SD
CV
1 4.14
5.6
6.95
9.0
2 41.84
25.6
27.96
20.5
3 59.09
28.2
27.84
14.4
# Points 20 172 32 123 6 44
# Labs 1 2 2 2 2 2
RANDOX RX imola
Mean 60.68 61.72 104.3 103.1 −− −−
SD
CV
1 1.68
2.8
2.21
3.6
2 1.72
1.7
2.09
2.0
3 −−
−−
−−
−−
# Points 26 227 24 196 −− −−
# Labs 1 1 1 1

Mean 65.29 64.54 110.7 110.1 169.7 167.8
SD
CV
1 1.44
2.2
2.00
3.1
2 1.51
1.4
3.35
3.0
3 3.59
2.1
5.01
3.0
# Points 316 15442 64 7269 286 16230
# Labs 7 35 2 18 6 35
Roche cobas 6000/8000/c 311 • HiSens

Mean −− 62.84 −− −− −− 178.3
SD
CV
1 −−
−−
1.48
2.4
2 −−
−−
−−
−−
3 −−
−−
3.58
2.0
# Points −− 373 −− −− −− 373
# Labs 1 1

Mean −− −− −− 111.8 −− 174.6
SD
CV
1 −−
−−
−−
−−
2 −−
−−
3.62
3.2
3 −−
−−
5.39
3.1
# Points −− −− −− 443 −− 445
# Labs 1 1
Roche cobas 6000/8000/c 311 • Roche 2nd generation LDL_C

Mean −− 65.16 −− 112.2 −− 169.0
SD
CV
1 −−
−−
1.09
1.7
2 −−
−−
2.71
2.4
3 −−
−−
3.60
2.1
# Points −− 390 −− 349 −− 735
# Labs 1 2 3
Roche cobas 6000/8000/c 311 • Roche Gen.3 LDLC3

Mean 63.79 65.03 109.8 112.0 165.5 168.5
SD
CV
1 1.41
2.2
1.87
2.9
2 2.76
2.5
3.37
3.0
3 3.51
2.1
4.42
2.6
# Points 861 21477 176 8443 894 22974
# Labs 14 54 4 24 14 57
Roche cobas 6000/8000/c 311 • Sekisui Nanopia

Mean −− −− −− 104.8 −− 160.4
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.52
2.4
3 −−
−−
2.49
1.6
# Points −− −− −− 403 −− 267
# Labs 2 2

Mean 66.24 65.98 113.1 114.0 174.3 172.8
SD
CV
1 2.20
3.3
1.77
2.7
2 3.03
2.7
2.99
2.6
3 2.37
1.4
4.56
2.6
# Points 99 2949 99 2844 48 2533
# Labs 3 13 3 10 2 12
Roche cobas c 303/503 • Roche Gen.3 LDLC3

Mean −− 61.03 −− −− −− 158.3
SD
CV
1 −−
−−
1.44
2.4
2 −−
−−
−−
−−
3 −−
−−
3.13
2.0
# Points −− 173 −− −− −− 177
# Labs 2 2

Roche cobas c 303/503 • Roche LDLC3, REF 08057966
Mean 63.64 65.16 109.0 112.0 169.3 169.8
SD
CV
1 1.48
2.3
1.81
2.8
2 0.868
0.8
2.05
1.8
3 3.81
2.3
4.68
2.8
# Points 192 7937 20 2670 86 7939
# Labs 5 23 1 6 3 21

Mean 64.88 64.86 111.7 112.3 170.8 171.6
SD
CV
1 1.63
2.5
2.02
3.1
2 2.25
2.0
3.07
2.7
3 3.76
2.2
4.13
2.4
# Points 165 1892 163 1890 62 703
# Labs 3 3 3 3 2 2
Roche cobas c 701/702 • Roche 2nd generation LDL_C

Mean −− 64.96 −− −− −− 169.7
SD
CV
1 −−
−−
0.928
1.4
2 −−
−−
−−
−−
3 −−
−−
2.44
1.4
# Points −− 23 −− −− −− 23
# Labs 1 1

Mean 65.74 61.28 −− 94.63 −− 124.2
SD
CV
1 0.773
1.2
3.53
5.8
2 −−
−−
4.91
5.2
3 −−
−−
13.34
10.7
# Points 31 383 −− 321 −− 321
# Labs 1 3 3 3

Mean −− 65.20 −− 114.6 −− 176.2
SD
CV
1 −−
−−
1.34
2.1
2 −−
−−
2.04
1.8
3 −−
−−
3.57
2.0
# Points −− 459 −− 626 −− 629
# Labs 2 2 2
Mean −− −− −− 107.9 −− 174.1
SD
CV
1 −−
−−
−−
−−
2 −−
−−
6.44
6.0
3 −−
−−
7.81
4.5
# Points −− −− −− 321 −− 318
# Labs 1 1
Roche Hitachi/MODULAR • Sekisui Diagnostics SEKURE

Mean −− 65.69 −− −− −− 168.0
SD
CV
1 −−
−−
1.55
2.4
2 −−
−−
−−
−−
3 −−
−−
3.65
2.2
# Points −− 277 −− −− −− 277
# Labs 1 1

Mean −− −− −− 97.00 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
4.19
4.3
3 −−
−−
−−
−−
# Points −− −− −− 25 −− −−
# Labs 1

Mean 70.05 67.24 −− 115.8 180.5 175.9
SD
CV
1 2.57
3.7
3.82
5.7
2 −−
−−
5.55
4.8
3 5.44
3.0
8.73
5.0
# Points 65 7349 −− 3032 66 7177
# Labs 2 22 16 2 22
Siemens ADVIA Chemistry Systems • Sekisui Diagnostics SEKURE

Mean −− −− 105.2 97.06 −− 147.3
SD
CV
1 −−
−−
−−
−−
1.16
1.1
2
9.86
10.2
3 −−
−−
15.20
10.3
# Points −− −− 2 220 −− 215
# Labs 1 2 2

Mean 62.08 69.40 118.8 114.4 179.4 180.6
SD
CV
1 4.00
6.4
3.75
5.4
2 4.08
3.4
7.90
6.9
3 3.87
2.2
8.46
4.7
# Points 41 12192 41 5186 30 10997
# Labs 5 56 5 30 1 49
Siemens Atellica CH Analyzer • Alternate Formulation/Standardization

Mean −− 67.01 −− −− −− 166.9
SD
CV
1 −−
−−
1.39
2.1
2−−
−−
−−
−−
3 −−
−−
3.04
1.8
# Points −− 108 −− −− −− 107
# Labs 2 2
Siemens Atellica CH Analyzer • Siemens Atellica CH DLDL, REF 11097632

Mean −− 60.00 −− 101.5 −− 158.0
SD
CV
1 −−
−−
0.000
0.0
2
−−
−−
2.10
2.1
3 −−
−−
2.00
1.3
# Points −− 3 −− 2 −− 3
# Labs 1 1 1
Siemens Atellica CH Analyzer • Siemens Atellica CH LDLC, REF 11537214

Mean 67.20 66.09 111.0 108.8 155.1 165.4
SD
CV
1 3.88
5.8
3.72
5.6
2
6.53
5.9
4.74
4.4
3 4.39
2.8
9.37
5.7
# Points 324 3820 263 1141 52 2555
# Labs 7 15 6 7 2 10

Mean 63.35 64.26 108.6 107.6 161.9 163.5
SD
CV
1 2.43
3.8
2.25
3.5
2 2.78
2.6
3.58
3.3
3 6.83
4.2
6.37
3.9
# Points 517 24900 102 5624 480 21931
# Labs 14 75 2 23 13 64

Mean 65.14 64.78 109.6 109.0 169.1 168.7
SD
CV
1 2.73
4.2
2.57
4.0
2 3.22
2.9
4.57
4.2
3 6.20
3.7
6.44
3.8
# Points 1116 104K 231 27276 969 99478
# Labs 32 238 7 68 34 226

Mean −− −− 105.1 104.1 −− −−
SD
CV
1 −−
−−
−−
−−
2 6.04
5.7
6.40
6.1
3 −−
−−
−−
−−
# Points −− −− 18 26 −− −−
# Labs 1 1
Toshiba−TBA
Mean −− −− −− −− −− 191.0
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
3.72
1.9
# Points −− −− −− −− −− 82
# Labs 1
Mean −− 64.60 −− 112.7 −− 175.7
SD
CV
1 −−
−−
3.45
5.3
2 −−
−−
6.85
6.1
3 −−
−−
9.67
5.5
# Points −− 456 −− 462 −− 482
# Labs 3 3 3

Mean −− 61.51 −− 99.14 −− 152.0
SD
CV
1 −−
−−
2.00
3.2
2 −−
−−
3.43
3.5
3 −−
−−
5.12
3.4
# Points −− 722 −− 723 −− 721
# Labs 4 4 4

Mean −− 62.44 −− 99.27 −− 151.5
SD
CV
1 −−
−−
2.02
3.2
2 −−
−−
3.56
3.6
3 −−
−−
5.71
3.8
# Points −− 626 −− 623 −− 618
# Labs 2 2 2

Mean 69.33 69.66 103.9 104.0 154.9 153.1
SD
CV
1 1.62
2.3
1.47
2.1
2 2.91
2.8
2.56
2.5
3 4.09
2.6
4.36
2.9
# Points 61 264 62 260 62 264
# Labs 2 2 2 2 2 2

Mean −− 65.72 −− −− −− 167.0
SD
CV
1 −−
−−
1.44
2.2
2 −−
−−
−−
−−
3 −−
−−
3.59
2.2
# Points −− 61 −− −− −− 61
# Labs 1 1

Mean 69.85 63.47 104.3 100.8 152.8 154.0
SD
CV
1 2.18
3.1
3.48
5.5
2 2.19
2.1
4.43
4.4
3 4.53
3.0
7.09
4.6
# Points 454 20044 177 8677 347 19858
# Labs 19 65 8 32 15 60

Mean 64.72 64.69 108.0 107.9 165.0 165.4
SD
CV
1 4.02
6.2
3.72
5.7
2 10.01
9.3
9.13
8.5
3 10.72
6.5
11.88
7.2
# Points 6962 315K 3663 151K 4766 320K
# Labs 214 964 131 529 148 898
Cholesterol, LDL Immunoprecipitation mg/dL

Mean −− 59.61 −− 98.15 −− 150.3
SD
CV
1 −−
−−
2.67
4.5
2 −−
−−
4.13
4.2
3 −−
−−
6.37
4.2
# Points −− 3600 −− 3571 −− 3578
# Labs 2 2 2
RANDOX RX daytona
Mean 59.00 58.08 102.5 91.09 −− 164.0
SD
CV
1 6.48
11.0
4.90
8.4
2 11.85
11.6
9.34
10.3
3 −−
−−
0.000
0.0
# Points 24 118 12 87 −− 1
# Labs 1 1 1 1 1

Mean −− 63.61 −− 104.3 −− −−
SD
CV
1 −−
−−
2.80
4.4
2 −−
−−
4.32
4.1
3 −−
−−
−−
−−
# Points −− 14 −− 12 −− −−
# Labs 2 2
Method Group • Immunoprecipitation

Mean 59.00 59.57 102.5 98.01 −− 150.3
SD
CV
1 6.48
11.0
2.79
4.7
2 11.85
11.6
4.47
4.6
3 −−
−−
6.37
4.2
# Points 24 3732 12 3670 −− 3579
# Labs 1 5 1 5 3
Cholesterol, LDL NMR Spectroscopy mg/dL

Mean −− 59.60 −− −− −− 146.6
SD
CV
1 −−
−−
2.35
3.9
2 −−
−−
−−
−−
3 −−
−−
6.21
4.2
# Points −− 260 −− −− −− 252
# Labs 1 1
Method Group • NMR Spectroscopy

Mean −− 59.60 −− −− −− 146.6
SD
CV
1 −−
−−
2.35
3.9
2 −−
−−
−−
−−
3 −−
−−
6.21
4.2
# Points −− 260 −− −− −− 252
# Labs 1 1
Cholesterol, LDL Polyethylene glycol (PEG) mg/dL

Mean −− 59.12 −− −− −− 146.5
SD
CV
1 −−
−−
1.62
2.7
2 −−
−−
−−
−−
3 −−
−−
2.83
1.9
# Points −− 649 −− −− −− 539
# Labs 1 1
ERBA XL−640
Mean −− 60.47 −− 103.2 −− −−
SD
CV
1 −−
−−
0.544
0.9
2 −−
−−
1.27
1.2
3 −−
−−
−−
−−
# Points −− 29 −− 28 −− −−
# Labs 1 1
Method Group • Polyethylene glycol (PEG)

Mean −− 59.17 −− 103.2 −− 146.5
SD
CV
1 −−
−−
1.61
2.7
2 −−
−−
1.27
1.2
3 −−
−−
2.83
1.9
# Points −− 678 −− 28 −− 539
# Labs 2 1 1
Cholesterol, Total Cholesterol oxidase, esterase, peroxidase mg/dL

Abbott Alinity c
Mean 109.8 108.9 178.0 176.2 268.8 264.8
SD
CV
1 2.08
1.9
2.15
2.0
2 4.40
2.5
4.28
2.4
3 5.58
2.1
5.95
2.2
# Points 230 23603 114 13203 208 24401
# Labs 7 64 4 33 6 61
Abbott Alinity c • Abbott Alinity c Chol2, REF 04T88

Mean 108.4 108.6 177.9 177.1 267.7 268.5
SD
CV
1 2.61
2.4
3.70
3.4
2 2.81
1.6
4.17
2.4
3 5.69
2.1
7.21
2.7
# Points 595 3683 444 2191 296 1891
# Labs 23 32 19 23 11 15
Abbott ARCHITECT (c, i, ci models)

Mean 110.8 110.1 179.4 178.2 268.3 267.7
SD
CV
1 1.65
1.5
1.75
1.6
2 2.79
1.6
2.64
1.5
3 3.27
1.2
2.99
1.1
# Points 483 28206 278 15868 435 27659
# Labs 17 87 12 58 15 80
Abbott ARCHITECT (c, i, ci models) • Abbott ARCH Chol2, REF 04S92

Mean 111.3 110.4 180.7 179.8 −− 270.0
SD
CV
1 2.53
2.3
2.54
2.3
2
3.99
2.2
4.52
2.5
3 −−
−−
5.01
1.9
# Points 585 4796 587 3211 −− 1757
# Labs 21 33 21 30 5

Abbott ARCHITECT (c, i, ci models) • Abbott ARCH Cholesterol, REF 7D62
Mean 111.9 110.1 179.3 178.1 269.8 268.1
SD
CV
1 0.910
0.8
1.47
1.3
2
1.32
0.7
1.92
1.1
3 1.89
0.7
2.59
1.0
# Points 21 2084 21 1564 21 2102
# Labs 1 7 1 5 1 7
Abbott ARCHITECT (c, i, ci models) • Biolabo

Mean −− 111.5 −− 178.7 −− 268.6
SD
CV
1 −−
−−
1.66
1.5
2 −−
−−
5.29
3.0
3 −−
−−
6.74
2.5
# Points −− 57 −− 101 −− 53
# Labs 1 2 1

Mean 106.0 106.5 174.8 175.6 267.7 266.9
SD
CV
1 3.15
3.0
3.02
2.8
2 4.86
2.8
4.99
2.8
3 8.19
3.1
7.36
2.8
# Points 862 33437 859 28104 291 33945
# Labs 30 109 32 91 12 95

Mean −− 113.5 −− 184.7 −− 278.1
SD
CV
1 −−
−−
1.54
1.4
2
−−
−−
2.66
1.4
3 −−
−−
4.44
1.6
# Points −− 131 −− 457 −− 454
# Labs 1 3 3

Mean 106.6 109.4 179.9 178.7 272.9 270.8
SD
CV
1 1.92
1.8
4.60
4.2
2 6.29
3.5
6.27
3.5
3 7.93
2.9
9.92
3.7
# Points 126 12446 225 27912 243 30246
# Labs 3 46 5 77 6 82

Mean −− 108.6 −− −− −− 274.0
SD
CV
1 −−
−−
1.86
1.7
2 −−
−−
−−
−−
3 −−
−−
5.17
1.9
# Points −− 217 −− −− −− 196
# Labs 1 1

Mean 105.6 105.3 173.6 172.9 264.8 262.9
SD
CV
1 1.99
1.9
2.59
2.5
3.25
1.9
2 4.31
2.5
3 4.22
1.6
6.08
2.3
# Points 1071 33734 666 13378 499 30576
# Labs 35 106 21 48 17 88
Beckman Coulter AU Series • Eiken Kagaku

Mean −− 105.2 −− −− −− 268.9
SD
CV
1 −−
−−
1.25
1.2
2 −−
−−
−−
−−
3 −−
−−
3.16
1.2
# Points −− 731 −− −− −− 731
# Labs 1 1

Mean −− 110.2 −− 177.8 −− 268.3
SD
CV
1 −−
−−
2.14
1.9
2 −−
−−
3.43
1.9
3 −−
−−
4.18
1.6
# Points −− 211 −− 211 −− 210
# Labs 1 1 1

Mean 111.2 111.2 181.7 181.6 274.5 275.0
SD
CV
1 2.71
2.4
2.61
2.3
2 4.72
2.6
4.28
2.4
3 6.53
2.4
6.04
2.2
# Points 61 649 61 654 61 654
# Labs 2 2 2 2 2 2

Mean −− 107.2 −− −− −− 274.8
SD
CV
1 −−
−−
1.76
1.6
2 −−
−−
−−
−−
3 −−
−−
3.98
1.4
# Points −− 1393 −− −− −− 1394
# Labs 3 3

Mean 110.8 108.4 −− 180.7 287.3 280.7
SD
CV
1 3.57
3.2
2.59
2.4
2 −−
−−
5.56
3.1
3 7.18
2.5
6.75
2.4
# Points 62 8306 −− 2345 63 8338
# Labs 2 30 8 2 27

Mean −− −− −− 185.1 −− 278.1
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.42
0.8
3 −−
−−
2.31
0.8
# Points −− −− −− 168 −− 166
# Labs 1 1
Dirui CS Series
Mean −− 111.4 −− 181.6 −− 274.0
SD
CV
1 −−
−−
1.50
1.3
2 −−
−−
2.12
1.2
3 −−
−−
3.99
1.5
# Points −− 866 −− 857 −− 862
# Labs 2 2 2

Mean 110.0 109.6 180.8 177.8 272.4 268.7
SD
CV
1 5.33
4.9
5.07
4.6
2 14.12
7.8
10.00
5.6
3 9.45
3.5
12.57
4.7
# Points 54 706 22 540 5 44
# Labs 3 4 2 4 1 2
ERBA XL−640
Mean −− 106.7 −− 172.6 −− −−
SD
CV
1 −−
−−
2.03
1.9
2 −−
−−
2.91
1.7
3 −−
−−
−−
−−
# Points −− 58 −− 58 −− −−
# Labs 1 1

Mean 101.5 102.1 175.4 174.7 −− −−
SD
CV
1 5.34
5.3
4.87
4.8
2 4.90
2.8
6.00
3.4
3 −−
−−
−−
−−
# Points 59 380 33 349 −− −−
# Labs 3 5 2 6

Mean −− 109.6 −− 176.1 −− 281.8
SD
CV
1 −−
−−
2.05
1.9
2 −−
−−
2.73
1.6
3 −−
−−
4.65
1.6
# Points −− 1892 −− 61 −− 1876
# Labs 6 1 6

Mean −− −− −− 180.9 −− 277.3
SD
CV
1 −−
−−
−−
−−
2 −−
−−
3.23
1.8
3 −−
−−
5.28
1.9
# Points −− −− −− 108 −− 107
# Labs 1 1

Mean −− 110.9 −− −− −− −−
SD
CV
1 −−
−−
0.770
0.7
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 66 −− −− −− −−
# Labs 1

Mean −− 110.4 −− −− −− 283.9
SD
CV
1 −−
−−
4.04
3.7
2 −−
−−
−−
−−
3 −−
−−
9.05
3.2
# Points −− 89 −− −− −− 91
# Labs 1 1

Mean −− 109.9 −− 181.4 −− 270.2
SD
CV
1 −−
−−
5.90
5.4
2 −−
−−
10.73
5.9
3 −−
−−
14.34
5.3
# Points −− 50 −− 22 −− 45
# Labs 2 1 2
ILab Series
Mean 112.0 113.3 181.1 184.8 −− −−
SD
CV
1 3.07
2.7
3.33
2.9
2 4.41
2.4
5.37
2.9
3 −−
−−
−−
−−
# Points 11 46 11 46 −− −−
# Labs 1 1 1 1
Mindray BS Series
Mean 107.9 108.8 174.0 176.6 263.0 265.8
SD
CV
1 1.55
1.4
2.37
2.2
2 2.32
1.3
3.81
2.2
3 3.87
1.5
5.87
2.2
# Points 21 453 21 467 21 466
# Labs 1 3 1 2 1 2

Mean −− −− −− 176.4 −− 265.2
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.96
1.1
3 −−
−−
2.69
1.0
# Points −− −− −− 148 −− 148
# Labs 1 1
Mindray CL Series
Mean −− −− −− 177.4 −− 268.5
SD
CV
1 −−
−−
−−
−−
2 −−
−−
4.26
2.4
3 −−
−−
6.52
2.4
# Points −− −− −− 90 −− 92
# Labs 1 1
RANDOX RX daytona
Mean −− 106.0 −− 173.9 288.0 288.0
SD
CV
1 −−
−−
8.96
8.4
2 −−
−−
13.08
7.5
3 0.000
0.0
0.000
0.0
# Points −− 165 −− 105 1 1
# Labs 1 1 1 1
RANDOX RX imola
Mean 109.2 109.8 179.2 179.3 −− −−
SD
CV
1 1.45
1.3
1.95
1.8
2 1.73
1.0
2.05
1.1
3 −−
−−
−−
−−
# Points 26 226 24 196 −− −−
# Labs 1 1 1 1

Mean 108.8 109.0 178.0 178.2 269.9 270.3
SD
CV
1 3.08
2.8
2.98
2.7
2 4.80
2.7
4.30
2.4
3 5.93
2.2
6.06
2.2
# Points 2315 72264 472 35193 2289 79376
# Labs 45 157 11 90 43 173

Mean 108.6 109.1 178.3 178.8 269.9 271.4
SD
CV
1 2.08
1.9
2.27
2.1
2 3.69
2.1
3.34
1.9
3 4.29
1.6
5.10
1.9
# Points 149 6457 110 5384 142 6146
# Labs 6 22 4 15 6 22

Roche cobas c 303/503 • Roche CHOL2, REF 08057443
Mean 109.5 109.0 178.1 177.0 271.7 270.4
SD
CV
1 1.95
1.8
2.44
2.2
2 2.28
1.3
2.72
1.5
3 4.31
1.6
5.70
2.1
# Points 339 10429 68 2983 164 10183
# Labs 9 34 2 8 5 30

Mean 108.0 107.2 177.5 175.4 270.0 270.4
SD
CV
1 2.69
2.5
2.93
2.7
2 3.30
1.9
4.22
2.4
3 5.86
2.2
4.79
1.8
# Points 151 1841 150 1786 66 812
# Labs 3 4 3 3 2 3

Mean 102.8 105.4 171.0 172.3 254.9 259.5
SD
CV
1 1.78
1.7
2.67
2.5
2 2.00
1.2
4.36
2.5
3 4.93
1.9
6.16
2.4
# Points 52 2738 32 2076 52 2733
# Labs 2 6 1 3 2 6

Mean 112.5 108.0 −− 176.5 278.0 267.7
SD
CV
1 1.16
1.0
3.35
3.1
2 −−
−−
3.38
1.9
3 1.55
0.6
5.48
2.0
# Points 31 345 −− 314 31 345
# Labs 1 1 1 1 1

Mean −− 110.2 −− 179.8 −− 270.9
SD
CV
1 −−
−−
2.03
1.8
2 −−
−−
2.88
1.6
3 −−
−−
3.21
1.2
# Points −− 609 −− 632 −− 608
# Labs 2 2 2
Mean −− −− −− 186.3 −− 278.0
SD
CV
1 −−
−−
−−
−−
2 −−
−−
4.49
2.4
3 −−
−−
6.79
2.4
# Points −− −− −− 359 −− 356
# Labs 1 1

Mean −− 111.9 −− −− −− 284.6
SD
CV
1 −−
−−
2.43
2.2
2 −−
−−
−−
−−
3 −−
−−
5.55
2.0
# Points −− 278 −− −− −− 278
# Labs 1 1

Mean −− −− −− 177.6 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
3.21
1.8
3 −−
−−
−−
−−
# Points −− −− −− 25 −− −−
# Labs 1

Mean 105.2 107.5 180.6 179.1 270.7 273.6
SD
CV
1 1.89
1.8
2.76
2.6
2 4.80
2.7
4.07
2.3
3 6.42
2.4
5.23
1.9
# Points 87 15973 88 12215 120 15862
# Labs 3 38 3 32 4 37

Mean 108.3 107.1 178.8 177.2 271.8 270.9
SD
CV
1 3.39
3.1
2.82
2.6
2 4.64
2.6
3.80
2.1
3 8.17
3.0
5.87
2.2
# Points 551 28486 456 16819 217 21025
# Labs 17 91 15 65 9 73

Siemens Atellica CH Analyzer • Siemens Atellica CH Chol_2, REF 11097609
Mean −− 107.6 −− −− −− 271.5
SD
CV
1 −−
−−
2.29
2.1
2
−−
−−
−−
−−
3 −−
−−
4.69
1.7
# Points −− 1252 −− −− −− 1248
# Labs 2 2

Mean 106.6 106.0 175.7 175.2 267.5 266.6
SD
CV
1 3.26
3.1
3.25
3.1
2 3.17
1.8
4.27
2.4
3 5.23
2.0
6.03
2.3
# Points 1072 70311 157 10082 1065 65219
# Labs 36 189 6 49 34 164

Mean 103.5 103.0 172.7 171.4 261.0 260.3
SD
CV
1 3.50
3.4
3.47
3.4
2 5.39
3.1
5.32
3.1
3 7.50
2.9
7.55
2.9
# Points 2690 211K 665 55202 2566 199K
# Labs 75 428 21 120 73 410

Mean −− −− 183.0 182.8 −− −−
SD
CV
1 −−
−−
−−
−−
2 4.88
2.7
4.83
2.6
3 −−
−−
−−
−−
# Points −− −− 21 30 −− −−
# Labs 1 1

Mean −− 109.8 −− 178.7 −− 267.8
SD
CV
1 −−
−−
2.94
2.7
2 −−
−−
3.87
2.2
3 −−
−−
5.88
2.2
# Points −− 105 −− 105 −− 105
# Labs 1 1 1
Toshiba−TBA
Mean −− −− −− −− −− 271.8
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
5.67
2.1
# Points −− −− −− −− −− 83
# Labs 1
Toshiba−TBA • Hitachi Medical Medex

Mean −− 109.1 −− −− −− 277.3
SD
CV
1 −−
−−
1.05
1.0
2 −−
−−
−−
−−
3 −−
−−
2.19
0.8
# Points −− 360 −− −− −− 360
# Labs 1 1
Mean −− 109.1 −− 177.8 −− 270.0
SD
CV
1 −−
−−
1.95
1.8
2 −−
−−
3.11
1.8
3 −−
−−
5.20
1.9
# Points −− 456 −− 460 −− 472
# Labs 3 3 3

Mean 103.0 105.1 178.5 181.9 275.7 282.9
SD
CV
1 4.71
4.6
3.62
3.4
2 7.00
3.9
5.12
2.8
3 7.46
2.7
7.79
2.8
# Points 91 8253 43 2821 108 7530
# Labs 5 63 3 29 4 49

Mean 105.0 105.0 182.3 182.8 278.1 280.4
SD
CV
1 3.09
2.9
3.28
3.1
2 3.76
2.1
5.40
3.0
3 8.70
3.1
7.59
2.7
# Points 261 979 57 667 275 927
# Labs 10 12 3 5 10 11

Mean −− 107.6 −− 186.1 −− 285.7
SD
CV
1 −−
−−
3.24
3.0
2 −−
−−
4.65
2.5
3 −−
−−
7.56
2.6
# Points −− 3836 −− 2528 −− 3869
# Labs 18 12 18

Mean −− 107.3 −− 187.1 −− 287.5
SD
CV
1 −−
−−
2.32
2.2
2 −−
−−
3.84
2.1
3 −−
−−
5.74
2.0
# Points −− 1196 −− 1158 −− 1220
# Labs 9 8 9

Mean −− 1443 −− −− −− 3878
SD
CV
1 −−
−−
3584
248.3
2 −−
−−
−−
−−
3 −−
−−
9477
244.4
# Points −− 783 −− −− −− 763
# Labs 4 4

Mean 106.5 107.0 187.5 185.7 286.9 288.1
SD
CV
1 3.46
3.3
3.30
3.1
2 1.81
1.0
4.17
2.2
3 8.07
2.8
6.89
2.4
# Points 84 2616 21 1013 60 2340
# Labs 3 13 1 6 3 13

Mean 106.8 105.7 190.1 190.3 290.4 286.9
SD
CV
1 2.67
2.5
3.09
2.9
2 3.04
1.6
3.98
2.1
3 4.84
1.7
7.10
2.5
# Points 126 753 97 321 97 732
# Labs 6 10 5 5 5 8

Mean −− 106.7 −− 184.6 −− −−
SD
CV
1 −−
−−
4.70
4.4
2 −−
−−
6.60
3.6
3 −−
−−
−−
−−
# Points −− 46 −− 46 −− −−
# Labs 1 1

Mean −− 113.1 −− −− −− 286.0
SD
CV
1 −−
−−
2.07
1.8
2 −−
−−
−−
−−
3 −−
−−
4.52
1.6
# Points −− 36 −− −− −− 35
# Labs 1 1

Mean −− 110.2 −− −− −− 279.0
SD
CV
1 −−
−−
3.86
3.5
2 −−
−−
−−
−−
3 −−
−−
7.65
2.7
# Points −− 252 −− −− −− 230
# Labs 1 1

Mean −− 113.4 −− −− −− 269.2
SD
CV
1 −−
−−
1.32
1.2
2 −−
−−
−−
−−
3 −−
−−
3.71
1.4
# Points −− 41 −− −− −− 40
# Labs 1 1

Mean 108.1 102.3 189.5 187.3 −− 284.2
SD
CV
1 1.89
1.8
5.16
5.0
2 3.29
1.7
5.55
3.0
3 −−
−−
6.94
2.4
# Points 54 1432 55 647 −− 925
# Labs 2 5 2 4 2

Mean −− 101.7 −− 183.3 −− 278.3
SD
CV
1 −−
−−
1.95
1.9
2 −−
−−
2.40
1.3
3 −−
−−
3.96
1.4
# Points −− 50 −− 77 −− 128
# Labs 1 2 3

Mean −− 104.8 −− 185.7 −− 280.4
SD
CV
1 −−
−−
2.69
2.6
2 −−
−−
8.98
4.8
3 −−
−−
7.61
2.7
# Points −− 1560 −− 543 −− 1568
# Labs 9 2 10

Mean 106.9 105.5 182.2 183.5 272.6 279.3
SD
CV
1 3.17
3.0
3.05
2.9
2 5.38
3.0
5.37
2.9
3 7.26
2.7
7.51
2.7
# Points 199 26550 158 11830 98 26757
# Labs 13 112 8 43 10 105

Mean 108.2 107.5 184.6 184.9 284.1 280.8
SD
CV
1 4.62
4.3
3.65
3.4
2 5.68
3.1
5.81
3.1
3 10.92
3.8
8.09
2.9
# Points 577 8259 295 2573 420 7196
# Labs 27 56 14 23 19 44

Mean 108.6 107.8 −− −− 285.0 282.8
SD
CV
1 1.87
1.7
2.93
2.7
2 −−
−−
−−
−−
3 3.50
1.2
5.57
2.0
# Points 16 575 −− −− 16 547
# Labs 1 1 1 1

Mean −− 107.9 −− −− −− 282.5
SD
CV
1 −−
−−
3.04
2.8
2 −−
−−
−−
−−
3 −−
−−
4.90
1.7
# Points −− 128 −− −− −− 127
# Labs 2 2
Method Group • Cholesterol oxidase, esterase, peroxidase

Mean 107.0 106.0 177.7 176.7 268.3 267.1
SD
CV
1 3.94
3.7
4.02
3.8
2
5.86
3.3
6.03
3.4
3 9.28
3.5
9.40
3.5
# Points 13144 639K 6311 280K 9962 627K
# Labs 415 1853 227 942 307 1705
Cholinesterase, Serum (PCHE) Acetyl choline U/L @ 37° C

Mean −− −− −− 6193 −− 7520
SD
CV
1 −−
−−
−−
−−
2 −−
−−
80.38
1.3
3 −−
−−
98.74
1.3
# Points −− −− −− 592 −− 594
# Labs 3 3

Mean −− 4674 −− −− −− 7816
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− 1 −− −− −− 1
# Labs 1 1

Mean −− 2512 −− −− −− 4250
SD
CV
1 −−
−−
67.76
2.7
2 −−
−−
−−
−−
3 −−
−−
130.4
3.1
# Points −− 27 −− −− −− 27
# Labs 1 1
Cholinesterase, Serum (PCHE) Acetyl choline U/L @ 37° C

Mean 4910 4874 6425 6336 7573 7455
SD
CV
1 88.59
1.8
110.7
2.3
2 95.46
1.5
148.9
2.3
3 131.8
1.7
183.4
2.5
# Points 62 184 62 184 62 184
# Labs 2 2 2 2 2 2
Method Group • Acetyl choline

Mean 4910 4572 6425 6227 7573 7396
SD
CV
1 88.59
1.8
796.1
17.4
2 95.46
1.5
117.8
1.9
3 131.8
1.7
599.7
8.1
# Points 62 212 62 776 62 806
# Labs 2 4 2 5 2 7
Cholinesterase, Serum (PCHE) Acetylthiocholine U/L @ 37° C

Mean −− 4296 −− 6177 −− 7065
SD
CV
1 −−
−−
727.6
16.9
2 −−
−−
124.3
2.0
3 −−
−−
1145
16.2
# Points −− 135 −− 115 −− 135
# Labs 2 1 2

Mean −− 4857 −− 6524 −− 7995
SD
CV
1 −−
−−
172.2
3.5
2 −−
−−
182.8
2.8
3 −−
−−
250.5
3.1
# Points −− 2890 −− 2890 −− 2897
# Labs 7 7 7

Mean 4482 4479 6022 6015 7336 7333
SD
CV
1 53.70
1.2
81.11
1.8
2 66.07
1.1
107.3
1.8
3 72.55
1.0
130.0
1.8
# Points 14 268 14 268 14 268
# Labs 1 1 1 1 1 1
Mean −− 4833 −− 6450 −− 7965
SD
CV
1 −−
−−
82.39
1.7
2 −−
−−
131.0
2.0
3 −−
−−
146.8
1.8
# Points −− 272 −− 620 −− 619
# Labs 1 2 2
Method Group • Acetylthiocholine

Mean 4482 4806 6022 6467 7336 7913
SD
CV
1 53.70
1.2
255.0
5.3
2 66.07
1.1
218.6
3.4
3 72.55
1.0
385.8
4.9
# Points 14 3565 14 3893 14 3919
# Labs 1 11 1 11 1 12
Cholinesterase, Serum (PCHE) Butyrylthiocholine (Trinder) U/L @ 37° C

Mean 5058 4955 7204 6990 8052 8014
SD
CV
1 554.4
11.0
478.7
9.7
2 456.1
6.3
364.2
5.2
3 911.5
11.3
772.6
9.6
# Points 359 5451 180 3162 301 5164
# Labs 13 19 9 17 11 19
Abbott ARCHITECT/Alinity (c, i, ci models) • Sekisui Cholestest

Mean 5132 5072 6915 6792 8429 8278
SD
CV
1 158.5
3.1
133.7
2.6
2189.3
2.7
159.9
2.4
3 235.0
2.8
206.1
2.5
# Points 35 1982 36 1950 36 1973
# Labs 5 5 5 5 5 5

Mean 4402 4443 6022 6006 7056 7313
SD
CV
1 120.6
2.7
187.0
4.2
2 145.3
2.4
278.3
4.6
3 175.8
2.5
399.6
5.5
# Points 93 10000 51 10105 44 11637
# Labs 4 39 3 40 3 45

Mean −− 6164 6105 6114 7454 7400
SD
CV
1 −−
−−
3924
63.7
2 424.1
6.9
1132
18.5
3 549.9
7.4
1068
14.4
# Points −− 1350 182 5773 181 6165
# Labs 9 5 20 4 20

Mean −− −− −− −− −− 275.5
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
5.29
1.9
# Points −− −− −− −− −− 1671
# Labs 2

Mean −− −− −− 7098 −− 8803
SD
CV
1 −−
−−
−−
−−
2 −−
−−
99.47
1.4
3 −−
−−
125.4
1.4
# Points −− −− −− 339 −− 339
# Labs 1 1

Mean −− −− −− 5791 −− 6972
SD
CV
1 −−
−−
−−
−−
2 −−
−−
52.78
0.9
3 −−
−−
68.32
1.0
# Points −− −− −− 166 −− 166
# Labs 1 1

Mean −− −− 6611 6772 8078 8321
SD
CV
1 −−
−−
−−
−−
2 128.2
1.9
308.4
4.6
3 201.9
2.5
342.0
4.1
# Points −− −− 32 134 32 135
# Labs 1 1 1 1

Mean −− 4315 −− −− −− 7194
SD
CV
1 −−
−−
76.41
1.8
2 −−
−−
−−
−−
3 −−
−−
146.7
2.0
# Points −− 90 −− −− −− 92
# Labs 1 1
Mindray BS Series
Mean −− 4386 −− 6017 −− 7500
SD
CV
1 −−
−−
61.65
1.4
2 −−
−−
111.9
1.9
3 −−
−−
139.9
1.9
# Points −− 303 −− 347 −− 347
# Labs 2 1 1

Mean 4455 4461 5884 5996 7285 7309
SD
CV
1 69.09
1.6
99.02
2.2
2 110.3
1.9
159.3
2.7
3 92.02
1.3
169.4
2.3
# Points 207 4554 132 5212 208 6958
# Labs 3 11 2 16 3 19

Mean 4486 4475 6047 6040 7409 7368
SD
CV
1 60.12
1.3
74.72
1.7
2 55.47
0.9
83.42
1.4
3 69.89
0.9
100.6
1.4
# Points 51 447 51 728 50 724
# Labs 1 1 1 2 1 2

Mean −− 4359 −− 5946 −− 7417
SD
CV
1 −−
−−
987.5
22.7
2 −−
−−
1306
22.0
3 −−
−−
1636
22.1
# Points −− 506 −− 506 −− 506
# Labs 2 2 2

Mean −− 5248 −− 7085 −− 8648
SD
CV
1 −−
−−
63.29
1.2
2 −−
−−
101.2
1.4
3 −−
−−
128.3
1.5
# Points −− 631 −− 632 −− 630
# Labs 2 2 2
Mean −− −− −− 6563 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
34.43
0.5
3 −−
−−
−−
−−
# Points −− −− −− 3 −− −−
# Labs 1

Mean −− −− −− 6523 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
285.2
4.4
3 −−
−−
−−
−−
# Points −− −− −− 6 −− −−
# Labs 1

Mean −− 5966 −− 7552 −− 9601
SD
CV
1 −−
−−
181.0
3.0
2 −−
−−
805.1
10.7
3 −−
−−
858.3
8.9
# Points −− 237 −− 561 −− 399
# Labs 2 4 3
Siemens ADVIA Chemistry Systems • LEADMAN

Mean −− −− 5695 5713 6973 7027
SD
CV
1 −−
−−
−−
−−
2 85.45
1.5
123.5
2.2
3 88.69
1.3
150.0
2.1
# Points −− −− 35 557 32 544
# Labs 1 2 1 2

Mean 6060 1124801 8294 1459428 10249 9195
SD
CV
1 106.6 2725264
1.8 242.3
2 88.88 3596029
1.1 246.4
3 116.0
1.1
2509
27.3
# Points 28 1329 30 1319 30 791
# Labs 1 9 1 9 1 8
Siemens Atellica CH Analyzer • Medical Analysis Systems (MAS)

Mean −− 4.75 −− 6.47 −− 7.97
SD
CV
1 −−
−−
0.073
1.5
2
−−
−−
0.088
1.4
3 −−
−−
0.130
1.6
# Points −− 311 −− 370 −− 330
# Labs 1 1 1

Mean −− −− 5.94 5.94 −− −−
SD
CV
1 −−
−−
−−
−−
2 0.000
0.0
0.000
0.0
3 −−
−−
−−
−−
# Points −− −− 1 1 −− −−
# Labs 1 1
Toshiba−TBA
Mean −− −− −− −− −− 7753
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
268.6
3.5
# Points −− −− −− −− −− 84
# Labs 1

Mean −− 4936 −− 6603 −− 8027
SD
CV
1 −−
−−
87.47
1.8
2 −−
−−
122.9
1.9
3 −−
−−
149.9
1.9
# Points −− 454 −− 460 −− 475
# Labs 3 3 3

Mean −− 1851 5966 5982 −− 137.8
SD
CV
1 −−
−−
2141
115.6
2 107.1
1.8
365.5
6.1
3 −−
−−
970.8
704.6
# Points −− 393 8 753 −− 225
# Labs 7 2 10 3

Mean −− 4541 −− 6035 −− 7307
SD
CV
1 −−
−−
488.2
10.8
2 −−
−−
484.6
8.0
3 −−
−−
579.7
7.9
# Points −− 296 −− 505 −− 503
# Labs 2 3 3

Mean −− 4912 −− 6340 −− 7605
SD
CV
1 −−
−−
428.4
8.7
2 −−
−−
589.4
9.3
3 −−
−−
674.3
8.9
# Points −− 30 −− 41 −− 41
# Labs 1 2 2

Mean −− 4353 −− −− −− 7082
SD
CV
1 −−
−−
36.73
0.8
2 −−
−−
−−
−−
3 −−
−−
69.76
1.0
# Points −− 119 −− −− −− 121
# Labs 2 2
Method Group • Butyrylthiocholine (Trinder)

Mean 4819 56898 6445 63162 7726 7174
SD
CV
1 545.9 634124
11.3 1114.5
2 766.2 765768
11.9 1212.4
3 845.2
10.9
1885
26.3
# Points 773 28483 738 33630 914 40020
# Labs 27 118 31 145 30 149
Cholinesterase, Serum (PCHE) Butyrylthiocholine − Siemens Dimension/Vista U/L @ 37° C

Mean −− 4639 −− −− −− 7913
SD
CV
1 −−
−−
134.4
2.9
2 −−
−−
−−
−−
3 −−
−−
226.5
2.9
# Points −− 351 −− −− −− 351
# Labs 1 1

Mean −− 5760 −− 7914 −− −−
SD
CV
1 −−
−−
158.6
2.8
2 −−
−−
187.7
2.4
3 −−
−−
−−
−−
# Points −− 45 −− 43 −− −−
# Labs 1 1

Mean −− −− −− 11047 −− 13277
SD
CV
1 −−
−−
−−
−−
2 −−
−−
228.6
2.1
3 −−
−−
249.4
1.9
# Points −− −− −− 151 −− 152
# Labs 1 1
Method Group • Butyrylthiocholine − Siemens Dimension/Vista

Mean 7225 7292 10392 10098 11502 11517
SD
CV
1 878.9
12.2
781.7
10.7
2
421.8
4.1
472.9
4.7
3 1514
13.2
1533
13.3
# Points 415 16096 215 12081 400 9840
# Labs 11 26 8 23 10 15
Cholinesterase, Serum (PCHE) Propionylthiocholine U/L @ 37° C

Mean −− 4773 −− 6415 −− 7968
SD
CV
1 −−
−−
335.2
7.0
2
−−
−−
125.8
2.0
3 −−
−−
366.6
4.6
# Points −− 10 −− 10 −− 9
# Labs 1 1 1
Method Group • Propionylthiocholine

Mean −− −− −− −− −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− −− −− −− −− −−
# Labs
Cholinesterase, Serum (PCHE) Trinder U/L @ 37° C

Mean −− −− −− 6874 −− 8503
SD
CV
1 −−
−−
−−
−−
2 −−
−−
252.2
3.7
3 −−
−−
306.0
3.6
# Points −− −− −− 574 −− 572
# Labs 2 2

Mean −− −− −− 34.19 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.670
2.0
3 −−
−−
−−
−−
# Points −− −− −− 49 −− −−
# Labs 1

Mean −− −− 6579 6788 8193 8413
SD
CV
1 −−
−−
−−
−−
2 358.2
5.4
279.9
4.1
3 406.2
5.0
328.4
3.9
# Points −− −− 5 398 4 398
# Labs 1 1 1 1

Mean −− −− 6470 6303 8000 7753
SD
CV
1 −−
−−
−−
−−
2 214.4
3.3
202.0
3.2
3 168.2
2.1
306.3
4.0
# Points −− −− 11 111 9 113
# Labs 2 2 2 2

Mean −− −− −− 6782 −− 8356
SD
CV
1 −−
−−
−−
−−
2 −−
−−
264.4
3.9
3 −−
−−
344.5
4.1
# Points −− −− −− 272 −− 271
# Labs 2 2
Roche Hitachi Systems (International) • Beijing Bai Tai

Mean −− −− −− 6327 −− 7759
SD
CV
1 −−
−−
−−
−−
2 −−
−−
131.2
2.1
3 −−
−−
149.8
1.9
# Points −− −− −− 223 −− 222
# Labs 1 1
Method Group • Trinder

Mean −− −− 6504 6518 8059 8297
SD
CV
1 −−
−−
−−
−−
2 259.9
4.0
1186
18.2
3 262.0
3.3
415.5
5.0
# Points −− −− 16 1627 13 1576
# Labs 3 9 3 8
CK (Creatine Kinase) Colorimetric U/L @ 25° C

Mean 4415 4528 −− −− 37884 38165
SD
CV
1 147.8
3.3
122.0
2.7
2 −−
−−
−−
−−
3 533.1
1.4
532.7
1.4
# Points 45 328 −− −− 38 293
# Labs 1 1 1 1

Mean −− 4058 −− −− −− 35308
SD
CV
1 −−
−−
203.8
5.0
2 −−
−−
−−
−−
3 −−
−−
948.3
2.7
# Points −− 539 −− −− −− 539
# Labs 2 2

Mean 4415 4236 −− −− 37884 36314
SD
CV
1 147.8
3.3
289.0
6.8
2 −−
−−
−−
−−
3 533.1
1.4
1596
4.4
# Points 45 867 −− −− 38 832
# Labs 1 3 1 3

Mean −− 66.93 −− 258.9 −− 567.8
SD
CV
1 −−
−−
7.40
11.1
2 −−
−−
2.85
1.1
3 −−
−−
50.87
9.0
# Points −− 235 −− 57 −− 223
# Labs 3 2 3

Mean −− 74.87 −− 242.4 −− 620.3
SD
CV
1 −−
−−
2.81
3.8
2 −−
−−
4.90
2.0
3 −−
−−
16.54
2.7
# Points −− 986 −− 588 −− 1583
# Labs 4 3 7

Mean 94.40 91.76 286.2 292.4 −− −−
SD
CV
1 11.28
12.0
6.96
7.6
2 11.24
3.9
10.82
3.7
3 −−
−−
−−
−−
# Points 5 144 4 113 −− −−
# Labs 1 3 1 2

Mean 74.40 74.09 −− −− 601.1 603.1
SD
CV
1 1.89
2.5
2.10
2.8
2 −−
−−
−−
−−
3 15.90
2.6
11.56
1.9
# Points 60 694 −− −− 60 589
# Labs 2 2 2 2

Mean −− 69.20 −− −− −− 599.7
SD
CV
1 −−
−−
3.01
4.3
2 −−
−−
−−
−−
3 −−
−−
11.67
1.9
# Points −− 265 −− −− −− 268
# Labs 2 2

Mean −− 65.65 −− −− −− 394.8
SD
CV
1 −−
−−
2.23
3.4
2 −−
−−
−−
−−
3 −−
−−
10.51
2.7
# Points −− 204 −− −− −− 208
# Labs 1 1

Mean −− 20.34 −− 78.99 −− 208.7
SD
CV
1 −−
−−
0.542
2.7
2 −−
−−
1.72
2.2
3 −−
−−
6.25
3.0
# Points −− 75 −− 75 −− 75
# Labs 1 1 1

Mean 75.94 72.01 286.2 235.6 601.1 584.6
SD
CV
1 6.33
8.3
11.05
15.4
2 11.24
3.9
52.46
22.3
3 15.90
2.6
85.61
14.6
# Points 65 2603 4 833 60 2946
# Labs 3 16 1 8 2 16
CK (Creatine Kinase) NAC activated U/L @ 25° C

Mean −− 79.46 −− −− −− 658.6
SD
CV
1 −−
−−
2.03
2.5
2 −−
−−
−−
−−
3 −−
−−
13.01
2.0
# Points −− 166 −− −− −− 455
# Labs 3 3

Mean −− 72.18 −− 244.1 −− 580.7
SD
CV
1 −−
−−
5.17
7.2
2 −−
−−
9.62
3.9
3 −−
−−
26.98
4.6
# Points −− 459 −− 112 −− 433
# Labs 2 1 2

Mean −− 74.74 −− −− −− 624.7
SD
CV
1 −−
−−
1.81
2.4
2 −−
−−
−−
−−
3 −−
−−
10.49
1.7
# Points −− 298 −− −− −− 297
# Labs 1 1

Mean 68.00 75.09 235.0 246.1 −− 618.9
SD
CV
1 0.000
0.0
3.66
4.9
2 0.000
0.0
6.07
2.5
3 −−
−−
11.61
1.9
# Points 1 953 1 989 −− 893
# Labs 1 2 1 2 1
Method Group • NAC activated

Mean 68.00 74.71 235.0 245.9 −− 620.4
SD
CV
1 0.000
0.0
4.22
5.7
2 0.000
0.0
6.54
2.7
3 −−
−−
30.22
4.9
# Points 1 1876 1 1101 −− 2078
# Labs 1 8 1 3 7

Mean 75.94 77.68 248.4 253.1 633.5 644.0
SD
CV
1 2.50
3.3
2.81
3.6
2 7.51
3.0
7.46
2.9
3 14.99
2.4
17.85
2.8
# Points 1370 53791 962 29718 753 51020
# Labs 49 195 36 122 26 160
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH Creatine Kinase REF 7D63
Mean 72.82 74.01 238.1 238.6 −− −−
SD
CV
1 6.43
8.8
2.78
3.8
2
10.92
4.6
7.74
3.2
3 −−
−−
−−
−−
# Points 31 372 31 348 −− −−
# Labs 2 2 2 2
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c CK, REF 08P42

Mean 74.88 73.89 245.2 242.2 −− −−
SD
CV
1 1.71
2.3
2.84
3.8
2 5.31
2.2
8.24
3.4
3 −−
−−
−−
−−
# Points 15 146 15 146 −− −−
# Labs 1 2 1 2

Abbott ARCHITECT/Alinity (c, i, ci models) • Beijing Strong Biotechnologies (BSBE)
Mean −− −− 247.7 249.4 607.1 618.1
SD
CV
1 −−
−−
−−
−−
21.34
0.5
11.93
4.8
3 1.87
0.3
11.78
1.9
# Points −− −− 23 554 24 471
# Labs 2 2 2 2

Mean 80.08 81.90 260.5 263.1 643.8 648.3
SD
CV
1 0.860
1.1
1.27
1.6
2 1.45
0.6
2.84
1.1
3 4.30
0.7
5.67
0.9
# Points 13 345 13 385 13 386
# Labs 1 1 1 1 1 1

Mean 64.01 66.83 215.0 225.2 546.3 559.5
SD
CV
1 3.74
5.8
4.84
7.2
2 13.72
6.4
16.04
7.1
3 30.54
5.6
32.13
5.7
# Points 1546 49266 1295 28770 618 43932
# Labs 52 172 43 110 21 142

Mean 74.65 72.91 251.7 252.5 631.2 632.0
SD
CV
1 2.02
2.7
5.21
7.1
2 4.86
1.9
10.62
4.2
3 12.69
2.0
31.96
5.1
# Points 43 2380 152 5476 195 7162
# Labs 2 9 3 15 5 20

Mean −− 78.01 −− 268.3 −− 695.0
SD
CV
1 −−
−−
3.58
4.6
2 −−
−−
11.20
4.2
3 −−
−−
24.90
3.6
# Points −− 217 −− 217 −− 216
# Labs 1 1 1

Mean 70.67 73.61 239.7 243.5 607.3 609.3
SD
CV
1 2.36
3.3
2.52
3.4
2 5.16
2.2
6.83
2.8
3 13.37
2.2
17.78
2.9
# Points 63 655 63 655 63 655
# Labs 2 2 2 2 2 2

Mean −− 76.80 −− −− −− 640.0
SD
CV
1 −−
−−
2.40
3.1
2 −−
−−
−−
−−
3 −−
−−
14.30
2.2
# Points −− 1408 −− −− −− 1403
# Labs 4 4

Mean −− 81.06 −− 264.7 −− 659.0
SD
CV
1 −−
−−
6.31
7.8
2 −−
−−
10.20
3.9
3 −−
−−
28.69
4.4
# Points −− 389 −− 336 −− 340
# Labs 2 2 2

Mean −− 79.31 −− 266.3 −− 655.5
SD
CV
1 −−
−−
2.58
3.3
2 −−
−−
8.07
3.0
3 −−
−−
18.80
2.9
# Points −− 3654 −− 2061 −− 3689
# Labs 10 4 10

Mean −− −− −− 249.0 −− 618.3
SD
CV
1 −−
−−
−−
−−
2 −−
−−
6.01
2.4
3 −−
−−
15.16
2.5
# Points −− −− −− 108 −− 107
# Labs 1 1

Mean −− 75.43 −− −− −− −−
SD
CV
1 −−
−−
1.40
1.9
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 61 −− −− −− −−
# Labs 1

Mean −− −− 247.7 249.1 −− 620.6
SD
CV
1 −−
−−
−−
−−
2
3.16
1.3
6.51
2.6
3 −−
−−
24.32
3.9
# Points −− −− 23 186 −− 180
# Labs 1 1 1

Mean −− 78.33 −− −− −− 605.0
SD
CV
1 −−
−−
3.87
4.9
2 −−
−−
−−
−−
3 −−
−−
18.83
3.1
# Points −− 9 −− −− −− 9
# Labs 1 1
Mindray BS Series
Mean −− 73.48 −− 252.8 −− 632.2
SD
CV
1 −−
−−
3.87
5.3
2 −−
−−
5.49
2.2
3 −−
−−
17.46
2.8
# Points −− 206 −− 371 −− 415
# Labs 2 2 2
RANDOX RX imola
Mean 79.07 83.66 240.5 253.1 −− −−
SD
CV
1 1.93
2.4
4.86
5.8
2 12.28
5.1
12.64
5.0
3 −−
−−
−−
−−
# Points 6 65 6 52 −− −−
# Labs 1 1 1 1

Mean 74.36 77.12 238.0 243.6 606.4 608.1
SD
CV
1 2.03
2.7
3.17
4.1
2 4.49
1.9
6.64
2.7
3 13.93
2.3
18.78
3.1
# Points 391 4572 64 4668 360 6414
# Labs 6 11 2 10 5 15
Roche cobas 6000/c 311 • Alternate Formulation/Standardization

Mean −− 77.38 −− 247.4 −− 607.3
SD
CV
1 −−
−−
2.03
2.6
2 −−
−−
4.60
1.9
3 −−
−−
10.49
1.7
# Points −− 240 −− 414 −− 176
# Labs 2 2 2
Roche cobas 8000

Mean −− 77.82 −− 248.0 −− 614.3
SD
CV
1 −−
−−
1.81
2.3
2 −−
−−
3.74
1.5
3 −−
−−
9.68
1.6
# Points −− 8491 −− 4828 −− 9129
# Labs 17 10 20

Mean 73.57 74.13 239.4 239.6 590.4 594.1
SD
CV
1 0.959
1.3
1.33
1.8
2
3.24
1.4
3.28
1.4
3 4.81
0.8
8.02
1.3
# Points 58 908 65 992 50 766
# Labs 2 2 2 2 2 2
Roche cobas c 303/503 • Roche CK, REF 08057460

Mean −− 72.73 −− −− −− 585.1
SD
CV
1 −−
−−
1.54
2.1
2 −−
−−
−−
−−
3 −−
−−
8.76
1.5
# Points −− 252 −− −− −− 252
# Labs 2 2

Mean 76.49 75.41 242.6 241.5 610.0 605.1
SD
CV
1 2.61
3.4
1.89
2.5
2 9.78
4.0
5.96
2.5
3 15.18
2.5
14.64
2.4
# Points 195 1497 196 1817 114 881
# Labs 4 5 4 5 3 5

Mean 81.13 82.65 255.8 260.7 636.8 656.5
SD
CV
1 0.850
1.0
10.48
12.7
2 10.07
3.9
32.54
12.5
3 4.49
0.7
82.06
12.5
# Points 31 828 31 828 31 828
# Labs 1 3 1 3 1 3

Mean −− 79.18 −− 252.9 −− 630.7
SD
CV
1 −−
−−
1.34
1.7
2 −−
−−
3.20
1.3
3 −−
−−
7.40
1.2
# Points −− 629 −− 459 −− 629
# Labs 2 2 2
Mean −− 73.35 −− 282.9 −− 650.5
SD
CV
1 −−
−−
2.08
2.8
2 −−
−−
10.25
3.6
3 −−
−−
52.55
8.1
# Points −− 274 −− 214 −− 463
# Labs 1 1 2

Mean −− −− −− 239.6 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
5.15
2.2
3 −−
−−
−−
−−
# Points −− −− −− 24 −− −−
# Labs 1

Mean 69.54 74.96 236.9 244.5 617.2 630.0
SD
CV
1 1.45
2.1
5.79
7.7
2 6.95
2.9
13.71
5.6
3 16.40
2.7
29.60
4.7
# Points 13 1446 48 1693 45 1932
# Labs 1 6 2 10 2 9

Mean 72.31 75.26 239.3 244.2 607.5 613.3
SD
CV
1 2.90
4.0
4.00
5.3
2 3.91
1.6
7.89
3.2
3 10.55
1.7
17.74
2.9
# Points 466 22934 375 12198 174 16958
# Labs 15 77 13 52 8 58

Mean 73.62 73.64 240.3 240.6 584.3 594.4
SD
CV
1 2.42
3.3
2.68
3.6
2 5.42
2.3
4.59
1.9
3 9.42
1.6
12.45
2.1
# Points 118 6553 65 1457 56 5061
# Labs 5 15 2 2 3 13
Siemens Dimension Series • IFCC 2002 (Enzymes)

Mean −− 74.11 −− 242.3 −− 603.5
SD
CV
1 −−
−−
2.46
3.3
2 −−
−−
4.81
2.0
3 −−
−−
15.24
2.5
# Points −− 3587 −− 2407 −− 2654
# Labs 7 3 6

Mean 72.83 74.28 −− 245.0 581.5 593.5
SD
CV
1 2.53
3.5
2.55
3.4
2 −−
−−
4.14
1.7
3 15.83
2.7
13.54
2.3
# Points 191 10203 −− 1443 163 8543
# Labs 5 20 4 6 16

Siemens Dimension Vista • IFCC 2002 (Enzymes)
Mean 72.05 75.30 231.7 243.0 577.4 595.9
SD
CV
1 2.25
3.1
2.55
3.4
2 3.24
1.4
8.09
3.3
3 9.79
1.7
12.55
2.1
# Points 96 6775 31 2055 96 6789
# Labs 3 16 1 5 3 16
Toshiba−TBA
Mean −− −− −− −− −− 654.3
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
16.42
2.5
# Points −− −− −− −− −− 68
# Labs 1

Mean −− 82.75 −− 260.7 −− 603.2
SD
CV
1 −−
−−
7.09
8.6
2 −−
−−
11.25
4.3
3 −−
−−
15.21
2.5
# Points −− 463 −− 463 −− 481
# Labs 3 3 3

Mean 66.70 67.73 −− −− 396.6 390.0
SD
CV
1 3.30
4.9
2.85
4.2
2 −−
−−
−−
−−
3 5.10
1.3
10.89
2.8
# Points 15 567 −− −− 15 571
# Labs 1 3 1 3

Mean −− 66.15 −− 188.3 −− 390.4
SD
CV
1 −−
−−
3.31
5.0
2 −−
−−
8.06
4.3
3 −−
−−
16.42
4.2
# Points −− 1033 −− 1020 −− 981
# Labs 9 9 8

Mean −− 66.49 −− 190.3 −− 392.1
SD
CV
1 −−
−−
3.06
4.6
2 −−
−−
7.01
3.7
3 −−
−−
13.86
3.5
# Points −− 1586 −− 1421 −− 1601
# Labs 11 10 11

Mean 64.08 64.15 176.3 185.3 −− 395.8
SD
CV
1 1.63
2.5
2.98
4.6
2 3.73
2.1
7.76
4.2
3 −−
−−
13.31
3.4
# Points 32 629 30 631 −− 515
# Labs 1 6 1 6 5

Mean 61.21 66.88 182.6 184.7 380.6 379.3
SD
CV
1 1.84
3.0
3.21
4.8
2 3.87
2.1
7.59
4.1
3 7.42
2.0
12.17
3.2
# Points 17 990 15 973 15 660
# Labs 1 7 1 7 1 5

Mean −− 67.61 −− 185.0 −− 384.5
SD
CV
1 −−
−−
3.80
5.6
2 −−
−−
10.47
5.7
3 −−
−−
16.38
4.3
# Points −− 38 −− 38 −− 42
# Labs 4 4 4

Mean 63.42 63.42 173.8 173.8 368.1 368.1
SD
CV
1 2.70
4.3
2.70
4.3
2 6.73
3.9
6.73
3.9
3 13.47
3.7
13.47
3.7
# Points 16 16 15 15 15 15
# Labs 1 1 1 1 1 1

Method Group • NAC activated
Mean 70.97 73.66 232.7 240.8 596.4 603.3
SD
CV
1 6.09
8.6
5.94
8.1
2 19.48
8.4
19.29
8.0
3 47.28
7.9
53.10
8.8
# Points 4668 186K 3453 108K 2750 175K
# Labs 154 631 120 415 91 556
CK (Creatine Kinase) NAC Activated − IFCC Ref. Proc., Calibrated U/L @ 37° C
Mean 73.43 74.78 237.0 244.6 601.8 618.8
SD
CV
1 1.56
2.1
3.18
4.3
2 2.79
1.2
9.36
3.8
3 9.13
1.5
24.07
3.9
# Points 72 2710 73 2708 73 2701
# Labs 6 6 6 6 6 6

Mean 75.36 76.86 248.4 255.2 633.1 636.8
SD
CV
1 2.57
3.4
4.62
6.0
2 7.51
3.0
12.68
5.0
3 13.95
2.2
37.91
6.0
# Points 230 10737 211 11412 204 12117
# Labs 6 30 7 29 6 35

Mean 74.23 77.42 252.6 258.0 643.9 651.1
SD
CV
1 1.75
2.4
3.68
4.8
2 2.07
0.8
9.27
3.6
3 5.73
0.9
24.26
3.7
# Points 19 28520 18 27583 19 28754
# Labs 2 69 1 62 1 69

Mean −− −− −− 251.5 −− 620.6
SD
CV
1 −−
−−
−−
−−
2 −−
−−
3.08
1.2
3 −−
−−
5.55
0.9
# Points −− −− −− 169 −− 169
# Labs 1 1

Mean 67.33 73.67 219.0 243.9 −− 631.0
SD
CV
1 5.43
8.1
7.54
10.2
2 15.76
7.2
18.64
7.6
3 −−
−−
0.000
0.0
# Points 9 54 5 55 −− 1
# Labs 1 1 1 1 1

Mean −− 79.16 −− 263.7 −− 658.1
SD
CV
1 −−
−−
1.98
2.5
2 −−
−−
5.97
2.3
3 −−
−−
15.43
2.3
# Points −− 714 −− 713 −− 687
# Labs 4 2 2

Mean −− 72.87 −− −− −− 616.0
SD
CV
1 −−
−−
1.33
1.8
2 −−
−−
−−
−−
3 −−
−−
12.47
2.0
# Points −− 89 −− −− −− 91
# Labs 1 1

Mean −− −− −− 241.0 −− 616.1
SD
CV
1 −−
−−
−−
−−
2 −−
−−
3.26
1.4
3 −−
−−
6.84
1.1
# Points −− −− −− 148 −− 148
# Labs 1 1

Mean 74.93 76.84 238.8 245.2 596.9 610.3
SD
CV
1 2.32
3.1
2.90
3.8
2 4.38
1.8
6.23
2.5
3 12.91
2.2
14.76
2.4
# Points 966 32441 221 15558 932 31380
# Labs 20 100 6 50 19 97
Roche cobas 6000/c 311 • 2nd Generation
Mean −− 78.63 −− 251.3 −− 625.5
SD
CV
1 −−
−−
1.92
2.4
2 −−
−−
4.45
1.8
3 −−
−−
9.88
1.6
# Points −− 1948 −− 1947 −− 1946
# Labs 4 4 4
Roche cobas 6000/c 311 • Roche CK, REF 08057460

Mean −− 75.00 −− 237.0 −− 591.0
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
0.000
0.0
3 −−
−−
0.000
0.0
# Points −− 1 −− 1 −− 1
# Labs 1 1 1
Roche cobas 8000

Mean 75.80 76.82 243.8 243.6 599.6 608.0
SD
CV
1 1.99
2.6
2.30
3.0
2 10.09
4.1
7.08
2.9
3 10.77
1.8
12.46
2.0
# Points 695 21656 62 8130 760 25364
# Labs 13 42 1 27 14 52

Mean 73.38 75.48 238.8 243.0 593.4 606.3
SD
CV
1 1.47
2.0
1.84
2.4
2 3.72
1.6
4.62
1.9
3 6.82
1.1
11.35
1.9
# Points 202 4492 195 4630 48 3515
# Labs 4 14 4 11 2 12

Mean 73.97 75.43 238.8 244.6 591.8 603.2
SD
CV
1 1.69
2.3
2.28
3.0
2 3.54
1.5
4.92
2.0
3 10.30
1.7
13.08
2.2
# Points 293 8369 133 2727 168 8039
# Labs 8 30 3 9 5 26

Mean 76.14 74.97 243.1 240.8 610.8 605.8
SD
CV
1 1.29
1.7
2.04
2.7
2 3.36
1.4
5.45
2.3
3 8.89
1.5
14.22
2.3
# Points 14 268 14 268 14 268
# Labs 1 1 1 1 1 1

Mean 76.00 76.10 238.0 239.2 589.0 593.5
SD
CV
1 2.00
2.6
2.40
3.2
2 4.00
1.7
5.22
2.2
3 7.00
1.2
14.26
2.4
# Points 32 1476 32 723 32 1485
# Labs 1 4 1 1 1 4
Mean −− −− −− 259.7 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.53
0.6
3 −−
−−
−−
−−
# Points −− −− −− 3 −− −−
# Labs 1

Mean 70.59 76.44 239.8 250.4 613.2 644.8
SD
CV
1 3.60
5.1
4.41
5.8
2 3.14
1.3
8.30
3.3
3 10.06
1.6
22.92
3.6
# Points 124 12707 60 9449 65 12205
# Labs 4 27 2 21 2 23

Mean 70.95 76.36 231.4 245.6 582.8 612.5
SD
CV
1 2.87
4.0
3.66
4.8
2 5.83
2.5
8.02
3.3
3 15.94
2.7
14.37
2.3
# Points 55 4074 55 2294 56 3200
# Labs 2 12 2 9 2 12
Mean 72.20 73.85 232.8 240.1 585.8 598.1
SD
CV
1 3.18
4.4
2.96
4.0
2 5.09
2.2
6.28
2.6
3 11.82
2.0
12.68
2.1
# Points 1300 70040 268 10218 1237 65071
# Labs 43 174 8 35 41 161

Mean 73.03 74.99 235.6 243.1 586.1 596.9
SD
CV
1 2.23
3.1
2.47
3.3
2 5.35
2.3
5.62
2.3
3 11.61
2.0
12.89
2.2
# Points 2568 204K 669 57957 2036 180K
# Labs 74 412 24 115 60 388

Mean −− −− 252.1 249.7 −− −−
SD
CV
1 −−
−−
−−
−−
2 3.46
1.4
3.85
1.5
3 −−
−−
−−
−−
# Points −− −− 2 4 −− −−
# Labs 1 1

Mean −− 64.42 −− −− −− 394.4
SD
CV
1 −−
−−
3.89
6.0
2 −−
−−
−−
−−
3 −−
−−
17.12
4.3
# Points −− 607 −− −− −− 607
# Labs 2 2

Mean −− 63.51 −− −− −− 388.7
SD
CV
1 −−
−−
3.73
5.9
2 −−
−−
−−
−−
3 −−
−−
13.34
3.4
# Points −− 437 −− −− −− 436
# Labs 2 2
Method Group • NAC Activated − IFCC Ref. Proc., Calibrated

Mean 73.53 75.34 238.0 247.3 592.3 606.4
SD
CV
1 2.78
3.8
3.09
4.1
2
7.15
3.0
9.75
3.9
3 15.78
2.7
24.98
4.1
# Points 6579 405K 2018 157K 5644 377K
# Labs 185 934 68 388 160 899
CK (Creatine Kinase) NAC Activated − IFCC Ref. Proc., Calibrated U/L

Mindray BS Series
Mean −− 74.81 −− 624.5 −− −−
SD
CV
1 −−
−−
1.72
2.3
2 −−
−−
7.53
1.2
3 −−
−−
−−
−−
# Points −− 223 −− 230 −− −−
# Labs 1 1

Mean −− 74.81 −− 624.5 −− −−
SD
CV
1 −−
−−
1.72
2.3
2 −−
−−
7.53
1.2
3 −−
−−
−−
−−
# Points −− 223 −− 230 −− −−
# Labs 1 1
CK (Creatine Kinase) NAC, Enzymatic−VITROS U/L @ 35° C

Mean −− 4.04 −− 11.27 −− −−
SD
CV
1 −−
−−
0.228
5.6
2 −−
−−
0.425
3.8
3 −−
−−
−−
−−
# Points −− 44 −− 44 −− −−
# Labs 1 1

Method Group • NAC, Enzymatic−VITROS
Mean −− 4.04 −− 11.27 −− −−
SD
CV
1 −−
−−
0.228
5.6
2 −−
−−
0.425
3.8
3 −−
−−
−−
−−
# Points −− 44 −− 44 −− −−
# Labs 1 1

Mean 63.51 72.15 189.5 299.8 398.8 412.6
SD
CV
1 2.28
3.6
5.44
7.5
2 4.14
2.2
215.0
71.7
3 6.78
1.7
18.08
4.4
# Points 21 820 35 1534 31 1036
# Labs 1 9 2 11 1 6

Mean −− 64.50 −− 197.4 −− 401.9
SD
CV
1 −−
−−
3.49
5.4
2 −−
−−
12.34
6.3
3 −−
−−
20.48
5.1
# Points −− 444 −− 109 −− 537
# Labs 2 3 4

Mean 64.21 65.45 175.0 190.8 359.4 392.9
SD
CV
1 3.30
5.1
3.84
5.9
2 7.61
4.3
11.18
5.9
3 16.10
4.5
19.46
5.0
# Points 18 17950 23 7541 22 17440
# Labs 1 93 1 33 1 88

Mean −− 66.07 −− 189.6 −− 393.2
SD
CV
1 −−
−−
3.58
5.4
2 −−
−−
10.10
5.3
3 −−
−−
18.44
4.7
# Points −− 19704 −− 6755 −− 18697
# Labs 101 35 97

Mean 66.94 65.71 187.4 188.2 390.4 395.9
SD
CV
1 3.11
4.7
4.17
6.3
2 9.11
4.9
9.90
5.3
3 19.15
4.9
21.36
5.4
# Points 240 3927 234 1084 171 3648
# Labs 15 45 11 18 11 40

Mean 65.83 67.35 183.0 188.4 381.8 386.4
SD
CV
1 4.30
6.5
4.10
6.1
2 7.85
4.3
10.44
5.5
3 16.93
4.4
17.03
4.4
# Points 617 7738 146 2670 592 7148
# Labs 29 58 9 23 28 51

Mean 65.53 66.43 179.7 184.6 379.0 384.8
SD
CV
1 4.89
7.5
3.84
5.8
2 12.89
7.2
10.67
5.8
3 16.81
4.4
17.01
4.4
# Points 127 808 51 331 113 701
# Labs 8 20 3 8 6 17

Mean 68.02 67.17 −− −− 391.3 390.1
SD
CV
1 3.64
5.4
3.63
5.4
2 −−
−−
−−
−−
3 12.32
3.1
12.44
3.2
# Points 101 158 −− −− 99 155
# Labs 7 8 7 8

Mean −− 62.00 −− 179.0 −− 378.0
SD
CV
1 −−
−−
3.20
5.2
2 −−
−−
7.40
4.1
3 −−
−−
14.90
3.9
# Points −− 33 −− 32 −− 32
# Labs 1 1 1

Mean −− 67.53 −− −− −− 378.2
SD
CV
1 −−
−−
2.00
3.0
2 −−
−−
−−
−−
3 −−
−−
12.18
3.2
# Points −− 223 −− −− −− 222
# Labs 2 2

Mean −− 77.02 −− −− −− 416.4
SD
CV
1 −−
−−
3.06
4.0
2 −−
−−
−−
−−
3 −−
−−
14.40
3.5
# Points −− 61 −− −− −− 61
# Labs 1 1

Mean −− 74.22 −− −− −− 411.9
SD
CV
1 −−
−−
3.76
5.1
2 −−
−−
−−
−−
3 −−
−−
34.34
8.3
# Points −− 202 −− −− −− 255
# Labs 1 1

Mean −− 67.50 −− 190.7 −− 400.9
SD
CV
1 −−
−−
2.10
3.1
2 −−
−−
5.58
2.9
3 −−
−−
9.90
2.5
# Points −− 29 −− 28 −− 29
# Labs 1 1 1

Mean −− 63.79 −− −− −− 403.3
SD
CV
1 −−
−−
3.68
5.8
2 −−
−−
−−
−−
3 −−
−−
7.82
1.9
# Points −− 123 −− −− −− 126
# Labs 2 2
Method Group • NAC, Enzymatic−VITROS

Mean 66.16 66.15 184.9 198.2 383.8 392.8
SD
CV
1 4.13
6.2
4.01
6.1
2 9.58
5.2
67.12
33.9
3 17.74
4.6
19.41
4.9
# Points 1124 52220 489 19997 1028 50087
# Labs 61 344 26 133 54 319
CK (Creatine Kinase) Rosalki, Other Modified U/L @ 25° C

Mean −− 76.31 −− −− −− 636.7
SD
CV
1 −−
−−
2.90
3.8
2 −−
−−
−−
−−
3 −−
−−
14.02
2.2
# Points −− 468 −− −− −− 485
# Labs 1 1
Method Group • Rosalki, Other Modified

Mean −− 76.31 −− −− −− 636.7
SD
CV
1 −−
−−
2.90
3.8
2 −−
−−
−−
−−
3 −−
−−
14.02
2.2
# Points −− 468 −− −− −− 485
# Labs 1 1

Mean −− 65.70 −− 216.3 −− 543.9
SD
CV
1 −−
−−
4.23
6.4
2 −−
−−
6.27
2.9
3 −−
−−
10.44
1.9
# Points −− 670 −− 653 −− 702
# Labs 1 1 1

Mean 72.08 75.70 −− 257.5 599.3 631.7
SD
CV
1 3.37
4.7
3.12
4.1
2 −−
−−
10.89
4.2
3 11.71
2.0
18.42
2.9
# Points 63 7341 −− 3109 72 6475
# Labs 2 26 12 2 23
Fuji Dri−Chem Series • Fuji Dri−Chem CPK−PIII, REF 9903080

Mean −− 88.80 −− 284.8 −− −−
SD
CV
1 −−
−−
3.11
3.5
2 −−
−−
8.32
2.9
3 −−
−−
−−
−−
# Points −− 5 −− 5 −− −−
# Labs 1 1

Mean −− 74.23 −− 239.1 −− 603.5
SD
CV
1 −−
−−
2.56
3.5
2 −−
−−
4.43
1.9
3 −−
−−
12.20
2.0
# Points −− 775 −− 86 −− 616
# Labs 3 2 2

Mean 71.55 74.74 236.4 241.3 588.1 595.0
SD
CV
1 2.71
3.8
2.33
3.1
2 3.09
1.3
4.62
1.9
3 7.01
1.2
10.06
1.7
# Points 64 5145 193 6407 226 9103
# Labs 2 13 3 7 4 16
Method Group • Rosalki, Other Modified

Mean 71.81 74.79 236.4 244.6 590.8 607.2
SD
CV
1 3.06
4.3
3.59
4.8
2 3.09
1.3
12.68
5.2
3 9.66
1.6
25.94
4.3
# Points 127 13936 193 10259 298 16894
# Labs 4 44 3 23 6 42
CK−MB Activity Immunoinhibition, enzymatic U/L @ 37° C

Mean −− 15.62 −− 54.92 −− −−
SD
CV
1 −−
−−
6.73
43.1
2 −−
−−
22.09
40.2
3 −−
−−
−−
−−
# Points −− 143 −− 143 −− −−
# Labs 2 2

Mean −− 3.00 −− −− −− −−
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 2 −− −− −− −−
# Labs 1

Mean −− 4.17 15.68 10.44 −− 24.01
SD
CV
1 −−
−−
1.34
32.1
2 2.30
14.7
3.44
33.0
3 −−
−−
8.15
33.9
# Points −− 819 33 2733 −− 3630
# Labs 6 2 12 15

Mean −− −− −− 11.77 18.26 17.52
SD
CV
1 −−
−−
−−
−−
2−−
−−
4.46
37.9
3 1.14
6.3
1.74
9.9
# Points −− −− −− 3 153 1476
# Labs 1 3 3

Mean −− −− −− 9.55 −− 20.95
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.652
6.8
3 −−
−−
0.945
4.5
# Points −− −− −− 165 −− 164
# Labs 1 1

Mean −− 4.63 −− −− −− 27.66
SD
CV
1 −−
−−
0.885
19.1
2 −−
−−
−−
−−
3 −−
−−
2.62
9.5
# Points −− 89 −− −− −− 90
# Labs 1 1
Mindray BS Series
Mean −− 3.67 −− 8.66 −− 18.41
SD
CV
1 −−
−−
1.06
28.9
2 −−
−−
0.787
9.1
3 −−
−−
1.03
5.6
# Points −− 89 −− 312 −− 313
# Labs 1 1 1

Mean −− −− −− 8.81 −− 18.11
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.21
13.8
3 −−
−−
1.47
8.1
# Points −− −− −− 1844 −− 1895
# Labs 6 6

Mean −− 11.46 51.43 49.61 18.36 18.46
SD
CV
1 −−
−−
2.29
20.0
2 3.08
6.0
3.33
6.7
3 0.970
5.3
1.04
5.6
# Points −− 149 26 263 46 191
# Labs 1 1 1 1 1

Mean −− 5.41 −− 11.06 −− 23.55
SD
CV
1 −−
−−
1.33
24.6
2 −−
−−
1.33
12.1
3 −−
−−
1.80
7.7
# Points −− 505 −− 505 −− 505
# Labs 2 2 2

Mean −− 5.49 −− 8.33 −− 14.61
SD
CV
1 −−
−−
1.52
27.6
2 −−
−−
1.80
21.7
3 −−
−−
2.56
17.5
# Points −− 624 −− 541 −− 627
# Labs 2 2 2

Mean −− −− −− 10.92 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.50
13.7
3 −−
−−
−−
−−
# Points −− −− −− 24 −− −−
# Labs 1

Mean −− 49.00 −− 36.91 −− 87.09
SD
CV
1 −−
−−
0.000
0.0
2
−−
−−
1.72
4.7
3 −−
−−
3.18
3.7
# Points −− 1 −− 22 −− 22
# Labs 1 1 1

Mean −− −− −− 248.5 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
10.32
4.2
3 −−
−−
−−
−−
# Points −− −− −− 54 −− −−
# Labs 1

Mean 24.50 24.50 44.10 44.10 −− −−
SD
CV
1 0.000
0.0
0.000
0.0
2 1.13
2.6
1.13
2.6
3 −−
−−
−−
−−
# Points 2 2 2 2 −− −−
# Labs 1 1 1 1

Mean 17.70 17.70 36.80 36.80 −− −−
SD
CV
1 0.000
0.0
0.000
0.0
2 0.000
0.0
0.000
0.0
3 −−
−−
−−
−−
# Points 1 1 1 1 −− −−
# Labs 1 1 1 1
Method Group • Immunoinhibition, enzymatic

Mean 22.23 5.93 31.93 14.32 18.36 21.47
SD
CV
1 3.93
17.7
3.81
64.3
2 17.80
55.8
23.95
167.2
3 0.970
5.3
7.62
35.5
# Points 3 2424 62 6609 46 7437
# Labs 2 19 5 32 1 30
CK−MB Activity Immunoinhibition, enzymatic U/L

Mean −− 2.28 −− 7.70 −− 17.50
SD
CV
1 −−
−−
0.665
29.2
2 −−
−−
1.36
17.7
3 −−
−−
1.48
8.4
# Points −− 116 −− 143 −− 142
# Labs 1 1 1
Method Group • Immunoinhibition, enzymatic

Mean −− 2.28 −− 7.70 −− 17.50
SD
CV
1 −−
−−
0.665
29.2
2 −−
−−
1.36
17.7
3 −−
−−
1.48
8.4
# Points −− 116 −− 143 −− 142
# Labs 1 1 1
CK−MB Activity NAC Activated − IFCC Ref. Proc., Calibrated U/L @ 37° C
Mean −− −− −− 14.17 −− 32.25
SD
CV
1 −−
−−
−−
−−
2 −−
−−
3.04
21.5
3 −−
−−
3.57
11.1
# Points −− −− −− 219 −− 218
# Labs 2 2

Mean −− 36.97 −− 10.50 −− 21.99
SD
CV
1 −−
−−
6.34
17.2
2 −−
−−
2.10
20.0
3 −−
−−
1.79
8.2
# Points −− 666 −− 28 −− 1255
# Labs 1 1 2

Mean −− 7.67 11.80 13.47 −− 35.70
SD
CV
1 −−
−−
2.25
29.4
2 3.67
31.1
2.71
20.1
3 −−
−−
0.000
0.0
# Points −− 37 5 58 −− 1
# Labs 1 1 1 1

Mean −− −− 9.08 9.26 18.96 18.68
SD
CV
1 −−
−−
−−
−−
2 1.17
12.9
1.14
12.4
3 1.33
7.0
1.54
8.2
# Points −− −− 21 758 41 805
# Labs 1 1 1 1
Mean −− −− −− 13.06 −− 31.23
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.25
9.6
3 −−
−−
2.02
6.5
# Points −− −− −− 391 −− 376
# Labs 1 1
CK−MB Activity NAC Activated − IFCC Ref. Proc., Calibrated U/L @ 37° C
Mean −− −− −− 30.54 −− 73.12
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.41
4.6
3 −−
−−
2.52
3.4
# Points −− −− −− 49 −− 48
# Labs 1 1
Siemens Dimension Series • Siemens Dimension MBI, REF DF32

Mean −− 1.57 −− −− −− −−
SD
CV
1 −−
−−
0.280
17.8
−−
−−
2 −−
−−
3 −−
−−
−−
−−
# Points −− 30 −− −− −− −−
# Labs 1
Toshiba−TBA
Mean −− −− −− −− −− 9.50
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
1.74
18.3
# Points −− −− −− −− −− 42
# Labs 1

Mean −− 34.04 9.60 11.84 18.96 23.81
SD
CV
1 −−
−−
11.09
32.6
2.11
21.9
2 4.35
36.7
3 1.33
7.0
8.49
35.6
# Points −− 733 26 1503 41 2745
# Labs 3 2 7 1 9
CK−MB Activity NAC Activated − IFCC Ref. Proc., Calibrated U/L

Mindray BS Series
Mean −− 4.60 −− 18.29 −− −−
SD
CV
1 −−
−−
0.750
16.3
2 −−
−−
1.17
6.4
3 −−
−−
−−
−−
# Points −− 20 −− 229 −− −−
# Labs 1 1

Mean −− 4.60 −− 18.29 −− −−
SD
CV
1 −−
−−
0.750
16.3
2 −−
−−
1.17
6.4
3 −−
−−
−−
−−
# Points −− 20 −− 229 −− −−
# Labs 1 1
CO2 (Carbon Dioxide) Calculated mEq/L

Mean 15.66 15.93 19.09 19.03 24.34 24.56
SD
CV
1 0.731
4.7
1.22
7.6
2 0.400
2.1
0.421
2.2
3 0.990
4.1
1.69
6.9
# Points 47 469 7 24 46 467
# Labs 2 4 1 2 2 3

Mean −− 16.62 −− −− −− 25.47
SD
CV
1 −−
−−
1.01
6.1
2 −−
−−
−−
−−
3 −−
−−
1.36
5.3
# Points −− 100 −− −− −− 100
# Labs 1 1

Mean −− 33.00 −− −− −− 46.20
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− 1 −− −− −− 1
# Labs 1 1
CO2 (Carbon Dioxide) Calculated mEq/L

Mean 15.66 16.08 19.09 19.03 24.34 24.76
SD
CV
1 0.731
4.7
1.40
8.7
2 0.400
2.1
0.421
2.2
3 0.990
4.1
1.90
7.7
# Points 47 570 7 24 46 568
# Labs 2 6 1 2 2 5
CO2 (Carbon Dioxide) Colorimetric mEq/L

Mean 15.11 15.12 18.11 17.92 23.98 23.73
SD
CV
1 1.11
7.4
1.28
8.4
2 1.32
7.3
1.38
7.7
3 1.71
7.1
1.98
8.3
# Points 45 1120 45 1063 43 1198
# Labs 2 5 2 2 2 5

Mean −− 16.71 −− −− −− 26.55
SD
CV
1 −−
−−
2.01
12.1
2 −−
−−
−−
−−
3 −−
−−
3.17
11.9
# Points −− 168 −− −− −− 185
# Labs 1 1

Mean −− 16.63 −− 19.43 −− 25.52
SD
CV
1 −−
−−
0.881
5.3
2 −−
−−
0.906
4.7
3 −−
−−
1.14
4.5
# Points −− 305 −− 303 −− 304
# Labs 1 1 1

Mean −− −− 19.96 19.25 26.19 25.67
SD
CV
1 −−
−−
−−
−−
2 1.47
7.4
1.47
7.6
3 1.70
6.5
1.89
7.4
# Points −− −− 32 484 31 487
# Labs 1 1 1 1

Mean −− 15.58 −− 18.20 −− 23.90
SD
CV
1 −−
−−
1.62
10.4
2 −−
−−
2.00
11.0
3 −−
−−
2.83
11.8
# Points −− 389 −− 395 −− 399
# Labs 2 2 2

Mean −− 17.86 −− −− −− 26.65
SD
CV
1 −−
−−
1.19
6.6
2 −−
−−
−−
−−
3 −−
−−
1.32
4.9
# Points −− 197 −− −− −− 198
# Labs 1 1

Mean 15.11 15.78 18.88 18.46 24.91 24.69
SD
CV
1 1.11
7.4
1.62
10.3
2 1.65
8.7
1.61
8.7
3 2.02
8.1
2.38
9.6
# Points 45 2179 77 2245 74 2771
# Labs 2 10 3 6 3 11
CO2 (Carbon Dioxide) Differential rate pH mEq/L

Mean −− −− −− 19.89 −− 26.67
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.844
4.2
3 −−
−−
1.03
3.8
# Points −− −− −− 593 −− 598
# Labs 3 3
CO2 (Carbon Dioxide) Differential rate pH mEq/L

Mean 16.68 16.94 −− −− 25.71 26.61
SD
CV
1 0.695
4.2
0.910
5.4
2 −−
−−
−−
−−
3 0.944
3.7
1.38
5.2
# Points 47 740 −− −− 45 723
# Labs 1 1 1 1
Method Group • Differential rate pH

Mean 16.68 16.94 −− 19.89 25.71 26.64
SD
CV
1 0.695
4.2
0.910
5.4
2 −−
−−
0.844
4.2
3 0.944
3.7
1.23
4.6
# Points 47 740 −− 593 45 1321
# Labs 1 1 3 1 4
CO2 (Carbon Dioxide) Enzymatic mEq/L

Mean −− 20.59 −− −− −− 28.97
SD
CV
1 −−
−−
1.34
6.5
2 −−
−−
−−
−−
3 −−
−−
1.43
4.9
# Points −− 75 −− −− −− 73
# Labs 1 1

Mean 15.22 15.61 17.37 18.41 24.11 24.36
SD
CV
1 1.37
9.0
1.38
8.8
2 1.63
9.4
1.59
8.6
3 2.12
8.8
1.88
7.7
# Points 1156 66566 504 34510 922 65581
# Labs 33 169 22 101 24 152
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c CO2, REF 07P72

Mean 15.69 15.96 −− −− 24.49 25.14
SD
CV
1 1.23
7.8
1.16
7.3
2
−−
−−
−−
−−
3 1.73
7.0
1.63
6.5
# Points 144 3638 −− −− 141 3613
# Labs 2 3 2 2
Abbott ARCHITECT/Alinity (c, i, ci models) • Alternate Calibration

Mean −− 15.58 −− 18.51 −− 24.68
SD
CV
1 −−
−−
0.765
4.9
2−−
−−
0.922
5.0
3 −−
−−
1.11
4.5
# Points −− 106 −− 104 −− 106
# Labs 1 1 1
Abbott ARCHITECT/Alinity (c, i, ci models) • Alternate Formulation/Standardization

Mean −− 15.99 −− 18.49 −− 24.37
SD
CV
1 −−
−−
1.50
9.4
2
−−
−−
1.52
8.2
3 −−
−−
1.91
7.8
# Points −− 246 −− 246 −− 246
# Labs 1 1 1

Mean −− −− −− 37.22 −− 45.24
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.58
4.2
3 −−
−−
1.46
3.2
# Points −− −− −− 580 −− 551
# Labs 2 2

Mean 16.91 16.99 20.19 20.20 26.82 26.99
SD
CV
1 1.17
6.9
1.14
6.7
2 1.31
6.5
1.41
7.0
3 1.58
5.9
1.78
6.6
# Points 1408 112K 1022 85172 1133 119K
# Labs 43 256 30 180 37 267

Mean −− −− 19.48 19.84 26.38 26.54
SD
CV
1 −−
−−
−−
−−
0.656
3.4
2 1.04
5.2
3 0.842
3.2
1.24
4.7
# Points −− −− 84 818 84 817
# Labs 2 2 2 2

Mean −− 17.27 −− 20.52 −− 28.15
SD
CV
1 −−
−−
0.860
5.0
2 −−
−−
1.01
4.9
3 −−
−−
1.40
5.0
# Points −− 558 −− 548 −− 544
# Labs 4 4 4

Mean −− 18.85 −− 22.24 −− 28.24
SD
CV
1 −−
−−
1.78
9.4
2 −−
−−
1.88
8.5
3 −−
−−
2.37
8.4
# Points −− 402 −− 402 −− 397
# Labs 1 1 1

Mean 16.45 16.34 19.63 19.45 26.21 26.07
SD
CV
1 0.472
2.9
0.703
4.3
2 0.557
2.8
0.761
3.9
3 0.764
2.9
1.06
4.1
# Points 62 659 62 658 62 659
# Labs 2 2 2 2 2 2

Mean −− −− 38.46 38.46 46.72 46.76
SD
CV
1 −−
−−
−−
−−
2 0.340
0.9
1.53
4.0
3 0.490
1.0
1.10
2.3
# Points −− −− 5 739 4 737
# Labs 1 2 1 2

Mean −− −− −− 20.66 −− 25.94
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.98
9.6
3 −−
−−
2.34
9.0
# Points −− −− −− 172 −− 172
# Labs 1 1

Mean −− −− 36.97 37.53 47.16 47.93
SD
CV
1 −−
−−
−−
−−
2 1.03
2.8
1.68
4.5
3 2.41
5.1
2.93
6.1
# Points −− −− 42 228 39 226
# Labs 3 3 3 3

Mean −− 17.61 −− 20.73 −− 27.73
SD
CV
1 −−
−−
1.59
9.0
2 −−
−−
1.86
9.0
3 −−
−−
2.52
9.1
# Points −− 3576 −− 2835 −− 3613
# Labs 9 7 9

Mean −− 14.84 −− −− −− 21.62
SD
CV
1 −−
−−
0.772
5.2
2 −−
−−
−−
−−
3 −−
−−
1.17
5.4
# Points −− 81 −− −− −− 83
# Labs 1 1
Hitachi Chemistry Series • TOYOBO

Mean −− 14.86 −− −− −− −−
SD
CV
1 −−
−−
1.34
9.0
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 66 −− −− −− −−
# Labs 1
Mindray BS Series
Mean 14.84 15.97 18.20 18.89 24.77 25.34
SD
CV
1 1.14
7.7
1.16
7.3
2 0.950
5.2
1.38
7.3
3 1.89
7.6
1.71
6.7
# Points 20 442 20 452 20 450
# Labs 1 3 1 2 1 2

Mean −− −− −− 37.87 −− 45.74
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.35
3.6
3 −−
−−
1.11
2.4
# Points −− −− −− 273 −− 268
# Labs 2 2

Mean 16.17 16.27 18.99 19.19 24.63 25.01
SD
CV
1 1.13
7.0
1.17
7.2
2 1.12
5.9
1.34
7.0
3 1.61
6.5
1.75
7.0
# Points 2726 81864 310 27732 2689 89417
# Labs 45 166 9 78 43 186

Mean 16.28 16.00 −− 18.86 25.64 24.77
SD
CV
1 0.756
4.6
1.30
8.1
2 −−
−−
1.30
6.9
3 1.71
6.7
1.77
7.2
# Points 43 10753 −− 8481 43 10818
# Labs 2 18 11 2 18
Roche cobas c 303/503 • Roche CO2−L, REF 08057494

Mean 16.55 15.81 19.87 18.80 25.45 24.73
SD
CV
1 1.27
7.7
1.31
8.3
2 0.644
3.2
1.55
8.2
3 1.99
7.8
1.91
7.7
# Points 384 14632 113 2241 263 14337
# Labs 7 27 2 6 5 25

Mean 17.35 16.26 18.29 18.30 24.09 23.41
SD
CV
1 1.20
6.9
1.59
9.8
2 1.33
7.3
1.74
9.5
3 1.69
7.0
1.49
6.4
# Points 76 453 14 644 14 550
# Labs 3 3 1 5 1 2

Mean 15.31 15.16 17.99 17.85 23.23 23.09
SD
CV
1 1.03
6.7
1.14
7.5
2
1.10
6.1
1.26
7.1
3 1.31
5.6
1.59
6.9
# Points 46 436 48 442 49 443
# Labs 1 1 1 1 1 1

Mean 16.58 16.72 20.00 19.61 24.71 25.10
SD
CV
1 1.16
7.0
1.28
7.6
2 1.00
5.0
1.14
5.8
3 1.05
4.2
1.89
7.5
# Points 84 3729 33 747 84 4994
# Labs 3 11 1 1 3 17

Mean 17.77 16.90 21.51 20.30 28.38 27.07
SD
CV
1 0.850
4.8
1.14
6.8
2 0.810
3.8
1.36
6.7
3 1.12
3.9
1.91
7.1
# Points 31 850 31 850 31 850
# Labs 1 3 1 3 1 3

Mean −− 17.20 −− 21.35 −− 29.32
SD
CV
1 −−
−−
0.797
4.6
2 −−
−−
0.871
4.1
3 −−
−−
1.21
4.1
# Points −− 584 −− 632 −− 631
# Labs 2 2 2

Mean −− −− −− 17.49 −− 23.79
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.32
7.5
3 −−
−−
1.74
7.3
# Points −− −− −− 342 −− 342
# Labs 1 1

Mean −− 17.09 −− 19.75 −− 25.74
SD
CV
1 −−
−−
1.39
8.1
2 −−
−−
1.47
7.5
3 −−
−−
2.08
8.1
# Points −− 284 −− 652 −− 648
# Labs 1 3 2

Mean −− −− −− 18.62 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.11
6.0
3 −−
−−
−−
−−
# Points −− −− −− 9 −− −−
# Labs 1

Mean 17.84 18.34 19.39 21.42 26.70 27.60
SD
CV
1 1.18
6.6
1.19
6.5
2 0.700
3.6
1.06
4.9
3 1.42
5.3
1.66
6.0
# Points 88 12384 21 8217 89 12195
# Labs 3 25 1 20 3 26

Mean 16.76 17.20 19.71 20.07 26.10 25.85
SD
CV
1 1.58
9.4
1.47
8.5
2 1.69
8.6
1.69
8.4
3 2.55
9.8
2.14
8.3
# Points 981 71987 604 41174 786 65030
# Labs 26 150 17 84 23 140

Mean 18.60 18.82 21.75 21.92 28.08 28.10
SD
CV
1 1.56
8.4
1.39
7.4
2 1.43
6.6
1.47
6.7
3 1.94
6.9
1.71
6.1
# Points 1534 103K 392 14450 1359 96831
# Labs 49 228 12 42 44 215

Mean 19.37 19.45 22.53 22.49 28.50 28.73
SD
CV
1 1.41
7.3
1.33
6.8
2 0.951
4.2
1.29
5.7
3 1.89
6.6
1.65
5.8
# Points 2274 236K 236 51362 2012 232K
# Labs 65 431 10 105 63 429
Thermo Konelab 20/30/60i • DCL

Mean −− −− 21.56 21.39 −− −−
SD
CV
1 −−
−−
−−
−−
2 2.40
11.1
2.63
12.3
3 −−
−−
−−
−−
# Points −− −− 7 11 −− −−
# Labs 1 1

Mean −− 18.96 −− 21.54 −− 27.91
SD
CV
1 −−
−−
1.35
7.1
2 −−
−−
1.32
6.1
3 −−
−−
1.68
6.0
# Points −− 107 −− 107 −− 106
# Labs 1 1 1
Toshiba−TBA
Mean −− −− −− −− −− 26.23
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
1.80
6.9
# Points −− −− −− −− −− 84
# Labs 1
Mean −− 16.94 −− 20.17 −− 26.78
SD
CV
1 −−
−−
1.16
6.9
2 −−
−−
1.25
6.2
3 −−
−−
1.81
6.8
# Points −− 453 −− 455 −− 476
# Labs 3 3 3

Mean 17.20 16.10 17.04 18.62 25.57 25.74
SD
CV
1 1.60
9.3
2.08
12.9
2 2.86
16.8
2.69
14.5
3 0.984
3.8
2.13
8.3
# Points 16 1016 51 1787 47 1259
# Labs 1 14 3 14 2 10

Mean −− 17.20 −− −− −− 26.25
SD
CV
1 −−
−−
1.23
7.2
2 −−
−−
−−
−−
3 −−
−−
1.60
6.1
# Points −− 342 −− −− −− 337
# Labs 1 1

Mean −− 14.45 −− −− −− 24.81
SD
CV
1 −−
−−
1.16
8.0
2 −−
−−
−−
−−
3 −−
−−
1.45
5.8
# Points −− 53 −− −− −− 52
# Labs 1 1

Mean −− 13.81 −− −− −− 23.99
SD
CV
1 −−
−−
1.59
11.5
2 −−
−−
−−
−−
3 −−
−−
2.38
9.9
# Points −− 136 −− −− −− 143
# Labs 1 1

Mean −− 13.68 −− −− −− 24.42
SD
CV
1 −−
−−
0.873
6.4
2 −−
−−
−−
−−
3 −−
−−
1.76
7.2
# Points −− 13 −− −− −− 13
# Labs 1 1

Mean −− 16.99 −− 17.04 −− 26.04
SD
CV
1 −−
−−
2.06
12.1
2 −−
−−
1.66
9.7
3 −−
−−
1.87
7.2
# Points −− 1509 −− 54 −− 1506
# Labs 6 1 6

Mean −− 14.72 −− −− −− 26.08
SD
CV
1 −−
−−
0.820
5.6
2 −−
−−
−−
−−
3 −−
−−
1.69
6.5
# Points −− 149 −− −− −− 157
# Labs 1 1

Mean −− 14.05 −− −− −− 26.25
SD
CV
1 −−
−−
0.510
3.6
2 −−
−−
−−
−−
3 −−
−−
1.38
5.3
# Points −− 107 −− −− −− 111
# Labs 1 1

Mean 17.16 16.65 −− 19.53 27.59 26.35
SD
CV
1 0.449
2.6
1.60
9.6
2 −−
−−
1.83
9.4
3 1.45
5.2
2.13
8.1
# Points 4 15744 −− 6297 4 16336
# Labs 1 99 45 1 104

Mean −− 16.77 −− 18.31 −− 26.67
SD
CV
1 −−
−−
1.85
11.0
2 −−
−−
0.999
5.5
3 −−
−−
2.41
9.1
# Points −− 252 −− 71 −− 270
# Labs 5 1 5

Mean 14.24 16.71 17.17 19.38 23.21 25.97
SD
CV
1 1.42
9.9
1.44
8.6
2 1.01
5.9
1.60
8.3
3 1.65
7.1
1.96
7.6
# Points 18 19426 23 8814 22 18942
# Labs 1 116 1 47 1 112

Mean 13.90 16.64 19.78 19.64 26.56 25.89
SD
CV
1 1.66
12.0
1.41
8.4
2 1.34
6.8
1.48
7.6
3 1.24
4.7
1.98
7.6
# Points 27 15664 5 7242 25 15003
# Labs 2 94 1 41 2 91

Mean −− 16.66 −− 19.51 −− 25.75
SD
CV
1 −−
−−
1.52
9.1
2 −−
−−
1.82
9.3
3 −−
−−
2.06
8.0
# Points −− 7756 −− 3714 −− 7414
# Labs 61 31 60

Mean 15.06 16.07 −− 19.38 27.25 25.85
SD
CV
1 1.34
8.9
1.45
9.0
2 −−
−−
1.26
6.5
3 1.62
5.9
1.86
7.2
# Points 85 3361 −− 741 90 3376
# Labs 2 25 4 2 24

Mean 14.99 16.03 15.06 19.10 23.64 25.12
SD
CV
1 1.54
10.2
1.47
9.2
2 1.19
7.9
1.69
8.9
3 2.33
9.8
2.09
8.3
# Points 75 2624 13 1337 76 2605
# Labs 4 21 2 14 4 21

Mean 15.87 16.22 18.85 18.79 25.78 26.16
SD
CV
1 1.79
11.3
1.92
11.9
2 2.32
12.3
2.09
11.1
3 2.32
9.0
2.36
9.0
# Points 655 5487 229 1882 672 5354
# Labs 29 41 13 14 28 40

Mean 15.83 15.97 18.83 19.07 24.86 25.26
SD
CV
1 1.29
8.1
1.40
8.8
2 1.26
6.7
1.45
7.6
3 1.89
7.6
1.86
7.3
# Points 473 2029 293 1015 402 1981
# Labs 22 29 14 18 21 28

Mean −− 14.36 −− −− −− 27.90
SD
CV
1 −−
−−
0.808
5.6
2 −−
−−
−−
−−
3 −−
−−
1.36
4.9
# Points −− 43 −− −− −− 43
# Labs 1 1

Mean −− −− −− −− −− 16.00
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− −− −− −− −− 1
# Labs 1

Mean 17.09 17.72 19.88 20.35 26.29 26.97
SD
CV
1 1.98
11.6
1.94
11.0
2 2.76
13.9
2.36
11.6
3 2.81
10.7
2.56
9.5
# Points 12364 801K 4030 317K 11029 800K
# Labs 347 2038 148 905 319 2032
CO2 (Carbon Dioxide) ISE direct mEq/L

Mean −− 18.88 −− 21.58 −− 27.65
SD
CV
1 −−
−−
1.49
7.9
2 −−
−−
0.752
3.5
3 −−
−−
2.10
7.6
# Points −− 45 −− 5 −− 72
# Labs 1 1 1

Mean −− 16.67 −− −− −− 25.25
SD
CV
1 −−
−−
1.55
9.3
2 −−
−−
−−
−−
3 −−
−−
2.00
7.9
# Points −− 579 −− −− −− 595
# Labs 2 2

Mean −− 16.53 −− 19.47 −− 26.14
SD
CV
1 −−
−−
1.48
8.9
2 −−
−−
1.82
9.4
3 −−
−−
1.94
7.4
# Points −− 833 −− 395 −− 857
# Labs 4 1 4

Mean −− 16.35 −− 17.37 −− 26.60
SD
CV
1 −−
−−
1.21
7.4
2 −−
−−
1.58
9.1
3 −−
−−
2.09
7.9
# Points −− 635 −− 87 −− 649
# Labs 3 1 3

Mean −− 15.43 −− 19.02 −− 25.58
SD
CV
1 −−
−−
1.38
8.9
2 −−
−−
1.59
8.4
3 −−
−−
1.64
6.4
# Points −− 458 −− 97 −− 472
# Labs 3 2 2

Mean −− 17.72 −− 20.69 −− 27.09
SD
CV
1 −−
−−
1.40
7.9
2 −−
−−
2.01
9.7
3 −−
−−
2.43
9.0
# Points −− 537 −− 254 −− 359
# Labs 4 2 3

Mean 16.32 16.24 −− −− 26.43 26.41
SD
CV
1 1.16
7.1
1.15
7.1
2 −−
−−
−−
−−
3 1.53
5.8
1.47
5.6
# Points 26 28 −− −− 22 24
# Labs 1 3 1 3

Mean 17.52 17.71 20.50 20.77 −− −−
SD
CV
1 1.00
5.7
0.839
4.7
2 0.786
3.8
1.07
5.1
3 −−
−−
−−
−−
# Points 32 132 30 130 −− −−
# Labs 1 1 1 1

Mean 16.98 16.64 20.50 19.74 26.43 26.13
SD
CV
1 1.22
7.2
1.57
9.4
2 0.786
3.8
2.01
10.2
3 1.53
5.8
2.10
8.1
# Points 58 3247 30 968 22 3028
# Labs 2 21 1 8 1 18
CO2 (Carbon Dioxide) ISE indirect mEq/L

Mean −− 17.21 −− 20.75 −− 27.71
SD
CV
1 −−
−−
0.930
5.4
2 −−
−−
1.07
5.1
3 −−
−−
1.42
5.1
# Points −− 1419 −− 1347 −− 1412
# Labs 4 2 4
CO2 (Carbon Dioxide) ISE indirect mEq/L

Mean 17.00 16.79 −− 19.96 26.00 26.72
SD
CV
1 1.30
7.6
1.14
6.8
2 −−
−−
1.54
7.7
3 1.40
5.4
1.25
4.7
# Points 30 14206 −− 4402 30 32441
# Labs 1 31 12 1 28

Mean −− 15.73 −− −− −− 23.83
SD
CV
1 −−
−−
1.27
8.1
2 −−
−−
−−
−−
3 −−
−−
1.81
7.6
# Points −− 586 −− −− −− 556
# Labs 1 1
Roche cobas c 303/503 • Roche CO2−L, REF 08057494

Mean −− 16.95 −− −− −− 26.05
SD
CV
1 −−
−−
0.379
2.2
2 −−
−−
−−
−−
3 −−
−−
0.705
2.7
# Points −− 4 −− −− −− 4
# Labs 1 1

Mean 18.35 18.90 −− 21.89 27.22 27.81
SD
CV
1 1.14
6.2
1.47
7.8
2 −−
−−
1.57
7.2
3 1.35
5.0
1.82
6.5
# Points 66 7654 −− 2413 66 5539
# Labs 2 13 4 2 11

Mean 17.93 17.46 −− 20.66 26.84 26.87
SD
CV
1 1.34
7.5
1.60
9.2
2 −−
−−
1.70
8.3
3 1.47
5.5
1.46
5.4
# Points 96 23867 −− 8162 96 39950
# Labs 3 50 18 3 45
CO2 (Carbon Dioxide) Manometric mEq/L

SFRI − ISE Series
Mean −− 17.84 −− 21.44 −− 27.70
SD
CV
1 −−
−−
1.46
8.2
2 −−
−−
1.40
6.5
3 −−
−−
1.56
5.6
# Points −− 695 −− 695 −− 695
# Labs 2 2 2
Method Group • Manometric

Mean −− 17.84 −− 21.44 −− 27.70
SD
CV
1 −−
−−
1.46
8.2
2 −−
−−
1.40
6.5
3 −−
−−
1.56
5.6
# Points −− 695 −− 695 −− 695
# Labs 2 2 2
Creatinine Alkaline picrate method mg/dL

Mean 0.814 0.854 1.63 1.76 −− 6.69
SD
CV
1 0.000
0.0
0.078
9.2
2 0.000
0.0
0.112
6.4
3 −−
−−
0.144
2.2
# Points 1 26 1 21 −− 2
# Labs 1 1 1 1 1

Mean 0.764 0.745 1.75 1.75 6.52 6.82
SD
CV
1 0.039
5.1
0.036
4.9
2 0.093
5.3
0.090
5.1
3 0.245
3.8
0.301
4.4
# Points 182 2176 131 1957 100 2549
# Labs 4 10 4 4 3 9

Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH Crea2, REF 04S95
Mean 0.793 0.796 1.74 1.75 −− 6.62
SD
CV
1 0.026
3.3
0.036
4.5
2
0.044
2.5
0.051
2.9
3 −−
−−
0.000
0.0
# Points 191 1157 190 1155 −− 1
# Labs 6 7 6 7 1
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c Crea2, REF 04T91

Mean 0.759 0.763 1.73 1.72 6.42 6.44
SD
CV
1 0.038
5.0
0.052
6.8
2
0.100
5.8
0.087
5.0
3 0.202
3.1
0.220
3.4
# Points 98 363 93 241 68 211
# Labs 6 6 6 6 5 5

Mean 0.797 0.795 1.77 1.75 6.39 6.39
SD
CV
1 0.026
3.3
0.033
4.1
2 0.046
2.6
0.065
3.7
3 0.236
3.7
0.251
3.9
# Points 990 28103 711 20967 841 27753
# Labs 21 51 18 38 14 48

Mean 0.821 0.784 1.80 1.74 6.67 6.38
SD
CV
1 0.060
7.3
0.037
4.7
2 0.000
0.0
0.078
4.5
3 0.289
4.3
0.233
3.7
# Points 4 27757 1 24837 7 28005
# Labs 2 61 1 57 1 61

Mean 0.778 0.792 −− −− 6.52 6.52
SD
CV
1 0.026
3.4
0.020
2.6
−−
−−
2 −−
−−
3 0.107
1.6
0.115
1.8
# Points 31 1382 −− −− 31 1384
# Labs 1 4 1 4
Beckman Coulter AU Series • Beckman Coulter AU Urine Creatinine Cal, Cat. # DR0091
Mean −− 0.801 −− 1.78 −− 6.49
SD
CV
1 −−
−−
0.034
4.2
−−
−−
2 0.058
3.2
3 −−
−−
0.237
3.7
# Points −− 158 −− 159 −− 54
# Labs 2 2 1
Beckman Coulter AU Series • Beckman Coulter LX/DX CREm

Mean −− 0.806 −− 1.77 −− 6.44
SD
CV
1 −−
−−
0.041
5.0
2 −−
−−
0.101
5.7
3 −−
−−
0.266
4.1
# Points −− 703 −− 697 −− 696
# Labs 1 1 1

Mean 0.984 0.976 1.71 1.70 5.62 5.60
SD
CV
1 0.020
2.1
0.023
2.4
2 0.030
1.8
0.043
2.5
3 0.097
1.7
0.117
2.1
# Points 62 656 62 656 62 656
# Labs 2 2 2 2 2 2

Mean −− 0.950 −− −− −− −−
SD
CV
1 −−
−−
0.032
3.4
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 8 −− −− −− −−
# Labs 1

Mean −− 0.801 −− −− −− 6.57
SD
CV
1 −−
−−
0.024
3.0
2 −−
−−
−−
−−
3 −−
−−
0.121
1.8
# Points −− 141 −− −− −− 141
# Labs 1 1

Beckman Coulter UniCel DxC Series • Beckman Coulter LX/DX CREm
Mean −− 0.828 −− 1.79 −− 6.60
SD
CV
1 −−
−−
0.046
5.6
−−
−−
2 0.047
2.6
3 −−
−−
0.119
1.8
# Points −− 391 −− 393 −− 390
# Labs 2 2 2

Mean 0.958 0.945 1.54 1.61 5.05 5.13
SD
CV
1 0.057
5.9
0.078
8.2
2 0.231
15.0
0.156
9.7
3 0.161
3.2
0.206
4.0
# Points 44 454 18 359 5 44
# Labs 2 3 1 3 1 2
ERBA XL−640
Mean −− 0.106 −− 0.185 −− −−
SD
CV
1 −−
−−
0.012
11.3
2 −−
−−
0.006
3.4
3 −−
−−
−−
−−
# Points −− 56 −− 56 −− −−
# Labs 1 1

Mean −− 769.2 −− −− −− 6776
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− 1 −− −− −− 1
# Labs 1 1

Mean −− 0.662 −− −− −− 5.80
SD
CV
1 −−
−−
0.057
8.6
2 −−
−−
−−
−−
3 −−
−−
0.358
6.2
# Points −− 612 −− −− −− 598
# Labs 2 2

Mean −− 0.755 −− −− −− 6.16
SD
CV
1 −−
−−
0.025
3.3
2 −−
−−
−−
−−
3 −−
−−
0.225
3.7
# Points −− 43 −− −− −− 47
# Labs 1 1
ILab Series
Mean 0.868 0.898 1.80 1.81 −− −−
SD
CV
1 0.057
6.6
0.048
5.3
2 0.104
5.8
0.075
4.1
3 −−
−−
−−
−−
# Points 11 45 11 45 −− −−
# Labs 1 1 1 1
Mindray BS Series
Mean 0.867 0.868 1.78 1.81 6.76 6.79
SD
CV
1 0.016
1.8
0.027
3.1
2 0.030
1.7
0.044
2.4
3 0.112
1.7
0.149
2.2
# Points 21 155 21 155 21 155
# Labs 1 1 1 1 1 1
RANDOX RX daytona
Mean 1.13 1.04 1.93 1.77 6.02 6.02
SD
CV
1 0.074
6.5
0.198
19.1
2 0.113
5.8
0.275
15.5
3 0.000
0.0
0.000
0.0
# Points 20 184 16 165 1 1
# Labs 1 1 1 1 1 1

Mean −− −− −− 1.66 −− 5.80
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.066
4.0
3 −−
−−
0.212
3.7
# Points −− −− −− 139 −− 140
# Labs 1 1

Roche cobas c 303/503 • Roche CREJ2, REF 08057532
Mean 0.790 0.791 −− −− −− −−
SD
CV
1 0.020
2.5
0.020
2.5
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points 108 166 −− −− −− −−
# Labs 2 2

Mean 0.730 0.746 1.64 1.71 −− 6.30
SD
CV
1 0.030
4.1
0.050
6.7
2 0.060
3.7
0.052
3.0
3 −−
−−
0.153
2.4
# Points 22 282 22 1251 −− 1226
# Labs 1 2 1 3 2

Mean −− 0.747 −− 1.68 −− 6.26
SD
CV
1 −−
−−
0.030
4.1
2 −−
−−
0.051
3.1
3 −−
−−
0.231
3.7
# Points −− 1536 −− 581 −− 1566
# Labs 3 5 3

Mean 0.864 0.873 −− 1.72 6.60 6.65
SD
CV
1 0.036
4.2
0.045
5.1
2 −−
−−
0.048
2.8
3 0.106
1.6
0.144
2.2
# Points 250 18540 −− 901 250 18264
# Labs 5 41 4 5 40

Mean 0.734 0.710 −− 1.79 6.84 6.80
SD
CV
1 0.037
5.0
0.035
5.0
2 −−
−−
0.059
3.3
3 0.106
1.6
0.113
1.7
# Points 289 40424 −− 3572 288 39716
# Labs 9 57 8 9 55
Method Group • Alkaline picrate method

Mean 0.803 0.782 1.76 1.74 6.48 6.61
SD
CV
1 0.068
8.5
2.17
277.5
2 0.076
4.3
0.090
5.2
3 0.317
4.9
19.26
291.2
# Points 2324 126K 1277 58307 1674 124K
# Labs 65 267 43 148 43 247
Creatinine Alkaline picrate method, IFCC−IDMS Standardized mg/dL

Mean 0.775 0.752 1.78 1.81 6.98 7.00
SD
CV
1 0.048
6.2
0.033
4.4
2 0.054
3.0
0.250
13.9
3 0.215
3.1
0.186
2.7
# Points 933 36115 259 12552 764 33122
# Labs 24 124 12 68 16 102
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH Crea2, REF 04S95

Mean 0.771 0.779 1.68 1.69 −− 6.70
SD
CV
1 0.057
7.4
0.044
5.7
2
0.126
7.5
0.137
8.1
3 −−
−−
0.118
1.8
# Points 367 3904 354 1727 −− 2350
# Labs 13 24 13 19 6

Mean 0.781 0.781 1.77 1.78 −− 6.67
SD
CV
1 0.045
5.8
0.049
6.3
2
0.078
4.4
0.113
6.3
3 −−
−−
0.086
1.3
# Points 189 550 189 550 −− 76
# Labs 7 10 7 11 3

Mean 0.794 0.795 1.77 1.77 6.56 6.47
SD
CV
1 0.046
5.7
0.035
4.4
2 0.077
4.3
0.061
3.4
3 0.168
2.6
0.238
3.7
# Points 1070 53655 995 24593 398 52561
# Labs 35 122 32 73 14 93

Beckman Coulter AU Series • Ausbio Lab Ltd.
Mean −− 0.805 −− 1.71 −− 6.24
SD
CV
1 −−
−−
0.021
2.6
2 −−
−−
0.031
1.8
3 −−
−−
0.101
1.6
# Points −− 2131 −− 2049 −− 2042
# Labs 2 2 2

Mean 0.760 0.783 −− 1.74 6.17 6.32
SD
CV
1 0.020
2.6
0.039
5.0
2 −−
−−
0.075
4.3
3 0.070
1.1
0.219
3.5
# Points 30 6691 −− 7227 32 6556
# Labs 1 15 12 1 13

Mean 0.775 0.790 1.78 1.76 6.47 6.47
SD
CV
1 0.029
3.8
0.036
4.6
2
0.084
4.7
0.079
4.5
3 0.118
1.8
0.194
3.0
# Points 419 18859 52 2779 369 18320
# Labs 6 42 2 19 4 38
Beckman Coulter AU Series • Beckman Coulter AU Urine Creatinine Cal, Cat. # DR0091
Mean 0.797 0.794 1.71 1.82 −− 6.72
SD
CV
1 0.047
5.9
0.030
3.8
2
0.085
5.0
0.067
3.7
3 −−
−−
0.251
3.7
# Points 52 1336 51 2789 −− 3356
# Labs 2 7 2 8 10
Beckman Coulter AU Series • Beckman Coulter LX/DX CREm

Mean −− 0.806 −− 1.78 −− 6.48
SD
CV
1 −−
−−
0.027
3.3
2 −−
−−
0.042
2.4
3 −−
−−
0.122
1.9
# Points −− 669 −− 647 −− 692
# Labs 1 1 1

Mean 0.799 0.789 −− 1.66 5.99 6.12
SD
CV
1 0.024
3.0
0.026
3.3
2 −−
−−
0.040
2.4
3 0.102
1.7
0.162
2.6
# Points 17 502 −− 188 16 508
# Labs 1 1 1 1 1

Mean −− 0.801 −− −− −− −−
SD
CV
1 −−
−−
0.027
3.4
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 864 −− −− −− −−
# Labs 2
Beckman Coulter UniCel DxC Series • Beckman Coulter LX/DX CR−S

Mean 0.779 0.782 −− 1.71 6.20 6.29
SD
CV
1 0.038
4.9
0.052
6.6
2
−−
−−
0.070
4.1
3 0.149
2.4
0.176
2.8
# Points 63 11901 −− 1914 64 11674
# Labs 2 29 5 2 27

Mean −− 0.776 −− 1.70 −− −−
SD
CV
1 −−
−−
0.032
4.1
2 −−
−−
0.058
3.4
3 −−
−−
−−
−−
# Points −− 82 −− 52 −− −−
# Labs 2 1
RANDOX RX imola
Mean 0.815 0.822 1.55 1.57 −− −−
SD
CV
1 0.024
2.9
0.027
3.2
2 0.034
2.2
0.047
3.0
3 −−
−−
−−
−−
# Points 26 227 24 197 −− −−
# Labs 1 1 1 1

Mean 0.770 0.776 1.68 1.70 5.99 6.02
SD
CV
1 0.047
6.1
0.046
5.9
2 0.060
3.6
0.080
4.7
3 0.221
3.7
0.200
3.3
# Points 783 32118 222 21926 724 32130
# Labs 16 83 7 63 14 81
Roche cobas 8000

Mean 0.780 0.776 1.79 1.72 6.04 6.06
SD
CV
1 0.034
4.3
0.038
4.9
2 0.077
4.3
0.064
3.7
3 0.172
2.8
0.200
3.3
# Points 1081 34683 47 12485 1142 37578
# Labs 18 42 1 25 19 47

Mean 0.775 0.777 1.69 1.71 5.96 5.96
SD
CV
1 0.027
3.4
0.029
3.8
2 0.044
2.6
0.046
2.7
3 0.106
1.8
0.136
2.3
# Points 251 4498 214 3354 121 3706
# Labs 7 13 5 9 5 11

Mean −− 0.884 −− −− −− 6.63
SD
CV
1 −−
−−
0.020
2.3
2 −−
−−
−−
−−
3 −−
−−
0.062
0.9
# Points −− 386 −− −− −− 394
# Labs 2 2
Roche cobas c 303/503 • Roche CREJ2, REF 08057532

Mean 0.797 0.275 −− 0.206 −− 1.81
SD
CV
1 0.022
2.8
0.313
113.7
2 −−
−−
0.227
110.4
3 −−
−−
2.23
123.1
# Points 27 868 −− 286 −− 815
# Labs 1 9 3 8

Mean 0.788 0.777 1.73 1.72 −− −−
SD
CV
1 0.031
3.9
0.038
4.8
2 0.068
3.9
0.072
4.2
3 −−
−−
−−
−−
# Points 98 1161 100 1408 −− −−
# Labs 1 1 1 1

Mean 0.803 0.819 −− 1.70 5.83 5.94
SD
CV
1 0.028
3.5
0.028
3.4
2 −−
−−
0.000
0.0
3 0.182
3.1
0.157
2.6
# Points 57 2010 −− 64 57 2010
# Labs 2 6 1 2 6
Mean −− −− −− 1.67 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.014
0.9
3 −−
−−
−−
−−
# Points −− −− −− 6 −− −−
# Labs 2

Mean −− −− −− 1.80 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.029
1.6
3 −−
−−
−−
−−
# Points −− −− −− 24 −− −−
# Labs 1

Mean 0.747 0.734 1.75 1.70 6.38 6.29
SD
CV
1 0.045
6.0
0.027
3.6
2 0.055
3.2
0.055
3.3
3 0.236
3.7
0.128
2.0
# Points 103 7747 72 5954 94 7790
# Labs 3 9 2 8 3 10

Mean 0.772 0.758 1.69 1.71 6.35 6.32
SD
CV
1 0.040
5.2
0.030
4.0
2 0.055
3.2
0.060
3.5
3 0.192
3.0
0.166
2.6
# Points 129 18862 69 10305 138 13155
# Labs 4 52 3 32 5 41
Siemens Atellica CH Analyzer • Siemens Atellica CH Crea_2 REF 11097596

Mean −− 0.754 −− −− −− 6.31
SD
CV
1 −−
−−
0.026
3.5
2−−
−−
−−
−−
3 −−
−−
0.144
2.3
# Points −− 1252 −− −− −− 1233
# Labs 2 2

Mean 0.863 0.865 1.72 1.72 6.63 6.64
SD
CV
1 0.043
5.0
0.049
5.6
2 0.058
3.4
0.063
3.7
3 0.131
2.0
0.168
2.5
# Points 1246 63673 368 11342 1067 57357
# Labs 42 162 13 39 36 147
Siemens Dimension Series • Factored, IFCC Correlated

Mean −− 0.862 −− 1.68 −− 6.66
SD
CV
1 −−
−−
0.042
4.9
2 −−
−−
0.053
3.1
3 −−
−−
0.145
2.2
# Points −− 5504 −− 126 −− 5414
# Labs 12 1 12

Mean 0.726 0.710 1.81 1.79 6.82 6.78
SD
CV
1 0.041
5.6
0.036
5.1
2 0.068
3.8
0.054
3.0
3 0.099
1.4
0.111
1.6
# Points 1589 106K 375 18883 1323 98180
# Labs 46 205 14 40 43 198
Siemens Dimension Vista • Factored, IFCC Correlated

Mean 0.741 0.707 −− 1.78 6.82 6.78
SD
CV
1 0.029
3.9
0.030
4.3
2 −−
−−
0.040
2.2
3 0.077
1.1
0.104
1.5
# Points 63 6374 −− 4158 63 6334
# Labs 2 12 9 2 12

Mean −− 0.753 −− 1.78 −− −−
SD
CV
1 −−
−−
0.027
3.6
2 −−
−−
0.042
2.4
3 −−
−−
−−
−−
# Points −− 81 −− 81 −− −−
# Labs 1 1
Method Group • Alkaline picrate method, IFCC−IDMS Standardized

Mean 0.781 0.772 1.74 1.74 6.48 6.52
SD
CV
1 0.058
7.4
0.070
9.0
2
0.089
5.1
0.125
7.1
3 0.399
6.2
0.421
6.5
# Points 8593 423K 3391 148K 6372 397K
# Labs 234 993 115 458 167 873
Creatinine Alkaline picrate−deprotein,end point, IFCC−IDMS Standardized mg/dL

Mean −− 0.760 −− 1.64 −− 6.48
SD
CV
1 −−
−−
0.019
2.5
2 −−
−−
0.023
1.4
3 −−
−−
0.089
1.4
# Points −− 58 −− 58 −− 58
# Labs 1 1 1

Mean 0.800 0.800 1.70 1.62 5.90 5.78
SD
CV
1 0.050
6.2
0.048
6.0
2 0.050
2.9
0.067
4.1
3 0.100
1.7
0.121
2.1
# Points 33 861 33 855 33 810
# Labs 1 1 1 1 1 1
Creatinine Alkaline picrate−deprotein,end point, IFCC−IDMS Standardized mg/dL

Mean 0.875 0.862 −− −− 6.71 6.61
SD
CV
1 0.026
3.0
0.034
3.9
2 −−
−−
−−
−−
3 0.081
1.2
0.161
2.4
# Points 47 1258 −− −− 47 1261
# Labs 2 2 2 2
Method Group • Alkaline picrate−deprotein,end point, IFCC−IDMS Standardized

Mean 0.844 0.835 1.70 1.63 6.37 6.29
SD
CV
1 0.053
6.2
0.051
6.2
2
0.050
2.9
0.065
4.0
3 0.409
6.4
0.427
6.8
# Points 80 2177 33 913 80 2129
# Labs 3 4 1 2 3 4
Creatinine Alkaline picrate−deproteinization, end point mg/dL

Mean −− 0.784 −− −− −− 6.22
SD
CV
1 −−
−−
0.016
2.0
2 −−
−−
−−
−−
3 −−
−−
0.076
1.2
# Points −− 1011 −− −− −− 993
# Labs 4 4

Mean −− 0.741 −− 1.57 −− 6.04
SD
CV
1 −−
−−
0.028
3.8
2 −−
−−
0.052
3.3
3 −−
−−
0.170
2.8
# Points −− 106 −− 104 −− 105
# Labs 1 1 1
Method Group • Alkaline picrate−deproteinization, end point

Mean −− 0.780 −− 1.57 −− 6.20
SD
CV
1 −−
−−
0.021
2.7
2 −−
−−
0.052
3.3
3 −−
−−
0.104
1.7
# Points −− 1117 −− 104 −− 1098
# Labs 5 1 5
Creatinine Alkaline picrate−kinetic rate blanked mg/dL

Mean −− 0.878 −− −− −− 6.65
SD
CV
1 −−
−−
0.032
3.7
2 −−
−−
−−
−−
3 −−
−−
0.086
1.3
# Points −− 621 −− −− −− 621
# Labs 2 2

Mean −− 0.738 −− 1.74 −− 6.39
SD
CV
1 −−
−−
0.031
4.2
2 −−
−−
0.130
7.5
3 −−
−−
0.099
1.5
# Points −− 3262 −− 472 −− 3006
# Labs 10 4 9

Mean −− 0.793 −− −− −− 6.39
SD
CV
1 −−
−−
0.028
3.5
2 −−
−−
−−
−−
3 −−
−−
0.074
1.2
# Points −− 86 −− −− −− 86
# Labs 1 1
Method Group • Alkaline picrate−kinetic rate blanked

Mean −− 0.742 −− 1.74 −− 6.56
SD
CV
1 −−
−−
0.059
8.0
2 −−
−−
0.130
7.5
3 −−
−−
0.208
3.2
# Points −− 6144 −− 472 −− 6010
# Labs 17 4 16
Creatinine Alkaline picrate−kinetic rate blanked,IFCC−IDMS Standardized mg/dL

Mean −− 0.798 −− −− −− 6.35
SD
CV
1 −−
−−
0.020
2.5
2 −−
−−
−−
−−
3 −−
−−
0.148
2.3
# Points −− 541 −− −− −− 577
# Labs 1 1

Mean −− 0.783 −− −− −− 6.58
SD
CV
1 −−
−−
0.048
6.2
2 −−
−−
−−
−−
3 −−
−−
0.226
3.4
# Points −− 258 −− −− −− 254
# Labs 1 1
Mindray CL Series
Mean −− −− −− 1.84 −− 6.95
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.038
2.1
3 −−
−−
0.135
1.9
# Points −− −− −− 90 −− 92
# Labs 1 1

Mean 0.754 0.768 1.64 1.71 5.96 6.05
SD
CV
1 0.025
3.3
0.042
5.4
2 0.063
3.8
0.074
4.4
3 0.172
2.9
0.199
3.3
# Points 36 1554 41 1173 38 1865
# Labs 1 4 1 5 1 6
Roche cobas 8000

Mean −− 0.783 −− 1.73 −− 6.12
SD
CV
1 −−
−−
0.027
3.4
2 −−
−−
0.060
3.5
3 −−
−−
0.140
2.3
# Points −− 3133 −− 309 −− 3441
# Labs 5 1 6
Roche Hitachi/MODULAR • Sekisui Clinimate

Mean −− 0.803 −− −− −− 6.58
SD
CV
1 −−
−−
0.046
5.7
2 −−
−−
−−
−−
3 −−
−−
0.198
3.0
# Points −− 280 −− −− −− 279
# Labs 1 1

Mean −− 0.751 1.73 1.72 −− 6.65
SD
CV
1 −−
−−
0.030
4.0
2 0.030
1.7
0.048
2.8
3 −−
−−
0.253
3.8
# Points −− 1807 31 1518 −− 484
# Labs 4 1 4 2

Mean −− 0.744 −− 1.69 −− −−
SD
CV
1 −−
−−
0.019
2.5
2 −−
−−
0.033
1.9
3 −−
−−
−−
−−
# Points −− 1681 −− 1685 −− −−
# Labs 2 2

Mean −− 0.890 −− −− −− 6.70
SD
CV
1 −−
−−
0.040
4.5
2 −−
−−
−−
−−
3 −−
−−
0.100
1.5
# Points −− 32 −− −− −− 33
# Labs 1 1

Mean 0.703 0.705 1.77 1.77 6.70 6.76
SD
CV
1 0.021
3.0
0.032
4.6
2 0.025
1.4
0.040
2.3
3 0.083
1.2
0.118
1.7
# Points 40 36237 32 12372 71 35673
# Labs 3 79 1 18 4 79
Creatinine Alkaline picrate−kinetic rate blanked,IFCC−IDMS Standardized mg/dL

Method Group • Alkaline picrate−kinetic rate blanked,IFCC−IDMS Standardized
Mean 0.727 0.718 1.71 1.75 6.44 6.67
SD
CV
1 0.034
4.7
0.042
5.8
2
0.071
4.2
0.054
3.1
3 0.376
5.8
0.258
3.9
# Points 76 45522 104 17146 109 42697
# Labs 4 98 3 31 5 98
Creatinine Alkaline picrate−no deproteinization, end point mg/dL

Mean −− 0.823 −− −− −− 6.72
SD
CV
1 −−
−−
0.048
5.8
2 −−
−−
−−
−−
3 −−
−−
0.167
2.5
# Points −− 87 −− −− −− 98
# Labs 1 1
Method Group • Alkaline picrate−no deproteinization, end point

Mean −− 0.823 −− −− −− 6.72
SD
CV
1 −−
−−
0.048
5.8
2
−−
−−
−−
−−
3 −−
−−
0.167
2.5
# Points −− 87 −− −− −− 98
# Labs 1 1
Creatinine Colorimetric mg/dL

Mean −− 0.800 −− 1.78 −− 6.21
SD
CV
1 −−
−−
0.044
5.5
2 −−
−−
0.032
1.8
3 −−
−−
0.276
4.4
# Points −− 549 −− 19 −− 512
# Labs 2 1 1
Beckman Coulter AU Series • Syva Creatinine Validity Test, REF 3TX19UL

Mean −− 67.86 −− 150.6 −− 556.1
SD
CV
1 −−
−−
2.42
3.6
2
−−
−−
4.64
3.1
3 −−
−−
15.44
2.8
# Points −− 580 −− 577 −− 575
# Labs 1 1 1

Mean 0.813 0.777 1.68 1.67 −− −−
SD
CV
1 0.022
2.7
0.030
3.9
2 0.063
3.8
0.057
3.4
3 −−
−−
−−
−−
# Points 6 122 5 121 −− −−
# Labs 1 2 1 2

Mean 0.779 0.756 1.71 1.67 0.830 0.830
SD
CV
1 0.037
4.8
0.034
4.6
2 0.076
4.4
0.068
4.1
3 0.000
0.0
0.000
0.0
# Points 28 68 28 68 1 1
# Labs 1 1 1 1 1 1
Roche cobas 8000

Mean −− 0.780 −− −− −− 6.07
SD
CV
1 −−
−−
0.020
2.6
2 −−
−−
−−
−−
3 −−
−−
0.080
1.3
# Points −− 19 −− −− −− 19
# Labs 1 1

Mean −− 0.825 −− −− −− 6.25
SD
CV
1 −−
−−
0.040
4.9
2 −−
−−
−−
−−
3 −−
−−
0.188
3.0
# Points −− 281 −− −− −− 280
# Labs 1 1
Creatinine Colorimetric mg/dL

Mean −− 0.837 −− −− −− 6.61
SD
CV
1 −−
−−
0.016
1.9
2 −−
−−
−−
−−
3 −−
−−
0.101
1.5
# Points −− 7 −− −− −− 7
# Labs 2 2

Mean −− 0.744 −− 1.80 −− 7.20
SD
CV
1 −−
−−
0.017
2.3
2 −−
−−
0.041
2.3
3 −−
−−
0.147
2.0
# Points −− 156 −− 154 −− 155
# Labs 1 1 1

Mean 0.785 22.62 1.71 93.23 0.830 210.5
SD
CV
1 0.037
4.7
31.46
139.1
2 0.074
4.3
72.60
77.9
3 0.000
0.0
265.9
126.3
# Points 34 1782 33 939 1 1549
# Labs 2 11 2 6 1 8
Creatinine Enzymatic mg/dL

Mean −− 0.859 −− −− −− 6.47
SD
CV
1 −−
−−
0.185
21.6
2 −−
−−
−−
−−
3 −−
−−
0.227
3.5
# Points −− 75 −− −− −− 38
# Labs 1 1

Mean 0.883 0.857 −− −− 6.91 6.78
SD
CV
1 0.037
4.2
0.047
5.5
2 −−
−−
−−
−−
3 0.093
1.4
0.100
1.5
# Points 132 4127 −− −− 133 4143
# Labs 2 6 2 6
Abbott ARCHITECT/Alinity (c, i, ci models) • Kanto Kagaku

Mean −− −− −− 1.76 −− 6.60
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.039
2.2
3 −−
−−
0.124
1.9
# Points −− −− −− 587 −− 581
# Labs 2 2
Abbott ARCHITECT/Alinity (c, i, ci models) • Maccura

Mean 0.828 0.822 1.72 1.71 6.60 6.56
SD
CV
1 0.018
2.2
0.019
2.3
2 0.023
1.3
0.023
1.4
3 0.065
1.0
0.057
0.9
# Points 57 901 57 822 57 900
# Labs 1 1 1 1 1 1
Abbott ARCHITECT/Alinity (c, i, ci models) • Sentinel MULTIGENT Creatinine (Enzymatic) REF 8L24
Mean 0.846 0.852 1.77 1.77 −− 6.77
SD
CV
1 0.015
1.8
0.024
2.8
2
0.018
1.0
0.029
1.6
3 −−
−−
0.136
2.0
# Points 7 182 7 122 −− 54
# Labs 1 3 1 2 1

Mean −− 0.838 −− 1.77 −− 6.70
SD
CV
1 −−
−−
0.022
2.6
2 −−
−−
0.042
2.4
3 −−
−−
0.111
1.7
# Points −− 2773 −− 1736 −− 3139
# Labs 5 3 6

Mean −− 0.799 −− 1.73 −− 6.50
SD
CV
1 −−
−−
0.030
3.7
2 −−
−−
0.041
2.4
3 −−
−−
0.131
2.0
# Points −− 209 −− 208 −− 208
# Labs 1 1 1

Beckman Coulter AU Series • Kanto Kagaku
Mean −− −− 1.80 1.73 6.66 6.42
SD
CV
1 −−
−−
−−
−−
2 0.006
0.4
0.048
2.8
3 0.026
0.4
0.152
2.4
# Points −− −− 5 730 4 699
# Labs 1 2 1 2
Beckman Coulter AU Series • MedicalSystem Biotechnology Angiotensin Converting Enzyme Kit

Mean 0.842 0.859 −− −− −− −−
SD
CV
1 0.018
2.1
0.022
2.6
−−
−−
2 −−
−−
3 −−
−−
−−
−−
# Points 62 691 −− −− −− −−
# Labs 2 2

Mean −− 0.778 −− 1.69 −− 6.22
SD
CV
1 −−
−−
0.048
6.2
2 −−
−−
0.067
4.0
3 −−
−−
0.185
3.0
# Points −− 46 −− 49 −− 49
# Labs 1 1 1

Mean −− −− −− 1.74 −− 6.53
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.059
3.4
3 −−
−−
0.288
4.4
# Points −− −− −− 171 −− 170
# Labs 1 1
Dirui CS Series
Mean −− 0.818 −− 1.72 −− 6.67
SD
CV
1 −−
−−
0.030
3.7
2 −−
−−
0.030
1.7
3 −−
−−
0.092
1.4
# Points −− 921 −− 913 −− 915
# Labs 2 2 2
Dirui CS Series • Kanto Kagaku

Mean −− −− 1.71 1.71 6.27 6.32
SD
CV
1 −−
−−
−−
−−
2 0.024
1.4
0.033
1.9
3 0.055
0.9
0.079
1.3
# Points −− −− 32 134 32 135
# Labs 1 1 1 1

Mean −− −− 1.78 1.76 6.61 6.57
SD
CV
1 −−
−−
−−
−−
2 0.036
2.0
0.058
3.3
3 0.116
1.8
0.209
3.2
# Points −− −− 12 113 9 113
# Labs 2 2 2 2

Mean −− −− −− 1.70 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.058
3.4
3 −−
−−
−−
−−
# Points −− −− −− 41 −− −−
# Labs 1
Fuji Dri−Chem Series • Fuji Dri−Chem CRE−PIII, REF 9903090

Mean 0.781 0.804 1.72 1.74 −− −−
SD
CV
1 0.054
7.0
0.049
6.1
0.125
7.3
2 0.094
5.4
3 −−
−−
−−
−−
# Points 56 352 56 323 −− −−
# Labs 3 4 3 5

Mean −− 0.859 −− 1.80 −− 6.86
SD
CV
1 −−
−−
0.040
4.7
2 −−
−−
0.075
4.2
3 −−
−−
0.246
3.6
# Points −− 3941 −− 2906 −− 3961
# Labs 9 7 9

Mean −− −− −− 1.78 −− 7.14
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.101
5.7
3 −−
−−
0.307
4.3
# Points −− −− −− 107 −− 107
# Labs 1 1

Mean −− 0.834 1.76 1.74 −− 6.83
SD
CV
1 −−
−−
0.033
3.9
2 0.095
5.4
0.063
3.6
3 −−
−−
0.279
4.1
# Points −− 92 24 183 −− 257
# Labs 1 1 1 2
Hitachi Chemistry Series • Shinotest

Mean −− 0.850 −− −− −− −−
SD
CV
1 −−
−−
0.017
2.0
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 76 −− −− −− −−
# Labs 1

Mean −− 0.751 −− 1.59 −− 6.06
SD
CV
1 −−
−−
0.069
9.2
2 −−
−−
0.140
8.8
3 −−
−−
0.521
8.6
# Points −− 203 −− 202 −− 201
# Labs 1 1 1
Mindray BS Series
Mean −− 0.912 −− 1.83 −− 6.93
SD
CV
1 −−
−−
0.027
3.0
2 −−
−−
0.020
1.1
3 −−
−−
0.085
1.2
# Points −− 89 −− 138 −− 138
# Labs 1 1 1

Mean −− −− −− 1.80 −− 6.84
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.134
7.4
3 −−
−−
0.504
7.4
# Points −− −− −− 189 −− 190
# Labs 1 1
Mindray CL Series • Kanto Kagaku

Mean −− −− −− 1.78 −− 6.68
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.030
1.7
3 −−
−−
0.082
1.2
# Points −− −− −− 269 −− 262
# Labs 2 2
Roche cobas 8000

Mean −− 0.833 −− 1.78 −− 6.82
SD
CV
1 −−
−−
0.022
2.6
2 −−
−−
0.053
3.0
3 −−
−−
0.149
2.2
# Points −− 227 −− 259 −− 257
# Labs 1 2 2

Mean −− 0.887 −− −− −− 6.64
SD
CV
1 −−
−−
0.021
2.3
2 −−
−−
−−
−−
3 −−
−−
0.137
2.1
# Points −− 1348 −− −− −− 1351
# Labs 2 2
Roche cobas c 303/503 • Roche CREP2, REF 08057524

Mean 0.900 0.890 −− −− 6.77 6.68
SD
CV
1 0.023
2.6
0.023
2.6
2 −−
−−
−−
−−
3 0.124
1.8
0.141
2.1
# Points 111 2289 −− −− 108 2283
# Labs 2 2 2 2

Mean 0.956 0.935 1.91 1.87 6.71 6.67
SD
CV
1 0.018
1.9
0.036
3.8
2 0.032
1.7
0.067
3.6
3 0.101
1.5
0.233
3.5
# Points 13 270 13 270 13 270
# Labs 1 1 1 1 1 1

Mean −− 0.861 −− 1.74 −− −−
SD
CV
1 −−
−−
0.027
3.2
2 −−
−−
0.034
2.0
3 −−
−−
−−
−−
# Points −− 104 −− 97 −− −−
# Labs 1 1

Mean −− 0.824 −− 1.71 −− 6.60
SD
CV
1 −−
−−
0.026
3.1
2 −−
−−
0.046
2.7
3 −−
−−
0.132
2.0
# Points −− 1808 −− 2187 −− 1852
# Labs 9 10 9

Mean −− 0.792 −− 1.72 −− 6.79
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
0.000
0.0
3 −−
−−
0.000
0.0
# Points −− 1 −− 1 −− 1
# Labs 1 1 1
Siemens ADVIA Chemistry Systems • Sentinel MULTIGENT Creatinine (Enzymatic) REF 8L24
Mean −− 0.805 −− 1.67 −− 6.83
SD
CV
1 −−
−−
0.017
2.1
−−
−−
2
0.140
8.4
3 −−
−−
0.138
2.0
# Points −− 7 −− 7 −− 7
# Labs 2 2 2

Mean 0.812 0.838 1.67 1.76 6.47 6.67
SD
CV
1 0.025
3.1
0.032
3.8
2 0.043
2.6
0.061
3.4
3 0.109
1.7
0.161
2.4
# Points 441 11872 394 8302 99 11106
# Labs 12 30 11 24 5 23
Siemens Atellica CH Analyzer • Siemens Atellica CH ECre3 REF 11537216

Mean −− 0.855 −− −− −− 6.70
SD
CV
1 −−
−−
0.020
2.3
−−
−−
2 −−
−−
3 −−
−−
0.094
1.4
# Points −− 250 −− −− −− 251
# Labs 2 2
Siemens Atellica CH Analyzer • Siemens Atellica CH ECre_2 REF 11097533

Mean 0.835 0.825 1.72 1.72 −− 6.63
SD
CV
1 0.024
2.9
0.024
3.0
0.029
1.7
2 0.029
1.7
3 −−
−−
0.116
1.8
# Points 4 845 4 4 −− 598
# Labs 1 3 1 1 2

Mean −− −− 1.78 1.77 −− −−
SD
CV
1 −−
−−
−−
−−
2 0.040
2.2
0.041
2.3
3 −−
−−
−−
−−
# Points −− −− 23 32 −− −−
# Labs 1 1
Toshiba−TBA
Mean −− −− −− −− −− 6.43
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
0.180
2.8
# Points −− −− −− −− −− 83
# Labs 1

Mean −− 0.861 −− 1.79 −− 6.84
SD
CV
1 −−
−−
0.019
2.2
2 −−
−−
0.029
1.6
3 −−
−−
0.094
1.4
# Points −− 435 −− 437 −− 453
# Labs 3 3 3

Mean −− 0.766 −− −− −− 7.31
SD
CV
1 −−
−−
0.025
3.2
2 −−
−−
−−
−−
3 −−
−−
0.171
2.3
# Points −− 261 −− −− −− 271
# Labs 1 1

Mean −− 0.766 −− −− −− 7.15
SD
CV
1 −−
−−
0.041
5.4
2 −−
−−
−−
−−
3 −−
−−
0.182
2.5
# Points −− 339 −− −− −− 340
# Labs 1 1

Mean 0.838 0.844 1.70 1.76 6.68 6.70
SD
CV
1 0.049
5.8
0.042
5.0
2 0.071
4.2
0.068
3.9
3 0.222
3.3
0.211
3.1
# Points 883 33397 627 21431 455 33936
# Labs 25 95 24 82 15 92
Creatinine Enzymatic IFCC−IDMS Standardized mg/dL

Mean 0.842 0.850 1.75 1.78 6.75 6.77
SD
CV
1 0.026
3.1
0.035
4.1
2 0.039
2.2
0.046
2.6
3 0.152
2.3
0.146
2.2
# Points 312 35549 276 27663 361 37528
# Labs 15 83 16 66 16 84
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c Crea Enz REF 08P01
Mean −− 0.842 −− 1.76 −− −−
SD
CV
1 −−
−−
0.011
1.3
2 −−
−−
0.017
1.0
3 −−
−−
−−
−−
# Points −− 99 −− 100 −− −−
# Labs 2 2

Mean −− 0.833 −− 1.69 −− 6.58
SD
CV
1 −−
−−
0.028
3.4
2 −−
−−
0.033
2.0
3 −−
−−
0.119
1.8
# Points −− 290 −− 12 −− 331
# Labs 3 2 3

Mean 0.847 0.864 −− −− 6.63 6.72
SD
CV
1 0.011
1.2
0.026
3.0
2 −−
−−
−−
−−
3 0.040
0.6
0.149
2.2
# Points 11 293 −− −− 11 294
# Labs 1 1 1 1

Mean 0.826 0.824 1.74 1.72 6.60 6.60
SD
CV
1 0.016
2.0
0.032
3.9
2 0.061
3.5
0.046
2.7
3 0.079
1.2
0.138
2.1
# Points 109 1717 109 1658 109 1765
# Labs 3 3 3 3 3 3

Mean 0.808 0.835 1.67 1.73 6.56 6.64
SD
CV
1 0.034
4.2
0.037
4.4
2 0.061
3.7
0.064
3.7
3 0.141
2.1
0.164
2.5
# Points 166 12564 149 15799 164 16379
# Labs 3 28 4 34 4 40

Mean −− −− −− 1.76 −− 6.62
SD
CV
1 −−
−−
−−
−−
2
−−
−−
0.039
2.2
3 −−
−−
0.122
1.8
# Points −− −− −− 304 −− 303
# Labs 2 2

Mean −− 0.816 −− 1.71 −− 6.52
SD
CV
1 −−
−−
0.044
5.4
2 −−
−−
0.115
6.7
3 −−
−−
0.270
4.1
# Points −− 1112 −− 1308 −− 1101
# Labs 8 9 8
Beckman Coulter AU Series • Beckman Coulter Urine Cal, B64606

Mean −− −− −− 1.88 −− 7.00
SD
CV
1 −−
−−
−−
−−
−−
−−
2 0.042
2.2
3 −−
−−
0.134
1.9
# Points −− −− −− 141 −− 141
# Labs 1 1
Beckman Coulter AU Series • Beijing Strong Biotechnologies (BSBE)

Mean 0.909 0.894 −− −− 7.00 6.89
SD
CV
1 0.033
3.6
0.032
3.6
2
−−
−−
−−
−−
3 0.135
1.9
0.168
2.4
# Points 42 626 −− −− 42 621
# Labs 2 2 2 2

Mean −− 0.680 −− 1.49 −− −−
SD
CV
1 −−
−−
0.010
1.5
2 −−
−−
0.061
4.1
3 −−
−−
−−
−−
# Points −− 3 −− 3 −− −−
# Labs 1 1

Mean 0.959 0.943 1.69 1.64 −− −−
SD
CV
1 0.021
2.2
0.030
3.2
2 0.034
2.0
0.075
4.5
3 −−
−−
−−
−−
# Points 10 257 10 200 −− −−
# Labs 1 1 1 1

Mean 0.900 0.899 1.87 1.83 6.65 6.69
SD
CV
1 0.026
2.9
0.029
3.2
2 0.037
2.0
0.037
2.0
3 0.140
2.1
0.175
2.6
# Points 1034 18044 44 3551 1035 17981
# Labs 18 55 1 10 18 55
Roche cobas 8000

Mean 0.905 0.896 −− 1.83 6.73 6.65
SD
CV
1 0.021
2.3
0.041
4.5
2 −−
−−
0.051
2.8
3 0.094
1.4
0.218
3.3
# Points 66 10409 −− 3936 66 12290
# Labs 1 24 14 1 29

Mean 0.879 0.893 1.84 1.83 6.64 6.70
SD
CV
1 0.015
1.7
0.028
3.2
2 0.037
2.0
0.036
2.0
3 0.059
0.9
0.085
1.3
# Points 57 3752 71 4098 50 3501
# Labs 2 9 2 7 2 9
Roche cobas c 303/503 • Roche CREP2, REF 08057524

Mean 0.889 0.888 −− 1.83 6.67 6.69
SD
CV
1 0.015
1.7
0.031
3.4
2 −−
−−
0.031
1.7
3 0.062
0.9
0.136
2.0
# Points 228 11790 −− 3542 224 12054
# Labs 7 21 4 7 21

Mean 0.912 0.891 1.87 1.88 6.70 6.64
SD
CV
1 0.018
2.0
0.059
6.7
2 0.035
1.9
0.039
2.1
3 0.106
1.6
0.251
3.8
# Points 50 559 50 729 51 842
# Labs 1 2 1 2 1 3

Mean −− 0.884 −− −− −− 6.58
SD
CV
1 −−
−−
0.026
3.0
2 −−
−−
−−
−−
3 −−
−−
0.148
2.2
# Points −− 987 −− −− −− 988
# Labs 4 4

Mean −− 0.757 −− 1.60 −− 6.15
SD
CV
1 −−
−−
0.045
6.0
2 −−
−−
0.059
3.7
3 −−
−−
0.160
2.6
# Points −− 580 −− 580 −− 580
# Labs 3 3 3

Mean −− −− −− 1.72 −− 6.81
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.035
2.0
3 −−
−−
0.116
1.7
# Points −− −− −− 312 −− 312
# Labs 1 1

Mean −− 0.843 −− 1.78 −− 6.77
SD
CV
1 −−
−−
0.021
2.5
2 −−
−−
0.035
2.0
3 −−
−−
0.070
1.0
# Points −− 316 −− 316 −− 315
# Labs 1 1 1
Mean −− 0.853 −− 1.72 −− 6.55
SD
CV
1 −−
−−
0.051
6.0
2 −−
−−
0.125
7.3
3 −−
−−
0.439
6.7
# Points −− 260 −− 577 −− 572
# Labs 1 2 2

Mean 0.810 0.814 1.69 1.71 6.55 6.63
SD
CV
1 0.020
2.5
0.026
3.2
2 0.050
3.0
0.047
2.7
3 0.080
1.2
0.122
1.8
# Points 22 7652 22 6608 22 7645
# Labs 1 13 1 13 1 13

Mean −− 0.847 −− 1.77 −− 6.68
SD
CV
1 −−
−−
0.022
2.6
2 −−
−−
0.024
1.4
3 −−
−−
0.079
1.2
# Points −− 1350 −− 26 −− 1193
# Labs 5 1 4

Mean 0.867 0.871 1.75 1.78 6.54 6.57
SD
CV
1 0.034
3.9
0.035
4.0
2 0.024
1.4
0.045
2.5
3 0.116
1.8
0.211
3.2
# Points 408 23637 52 7534 397 20367
# Labs 11 57 2 23 10 47
Siemens Dimension Series • Sentinel

Mean −− 0.823 −− −− −− 6.57
SD
CV
1 −−
−−
0.025
3.1
2 −−
−−
−−
−−
3 −−
−−
0.066
1.0
# Points −− 165 −− −− −− 165
# Labs 2 2

Mean 0.849 0.854 1.75 1.76 6.62 6.64
SD
CV
1 0.034
4.0
0.035
4.1
2 0.039
2.2
0.045
2.6
3 0.099
1.5
0.122
1.8
# Points 1403 90190 673 50225 1111 71208
# Labs 31 136 17 71 23 120
Method Group • Enzymatic IFCC−IDMS Standardized

Mean 0.867 0.860 1.75 1.77 6.64 6.67
SD
CV
1 0.041
4.7
0.040
4.7
2 0.062
3.5
0.060
3.4
3 0.137
2.1
0.170
2.5
# Points 3918 222K 1456 129K 3643 208K
# Labs 97 465 48 272 89 456
Creatinine Enzymatic−VITROS, IFCC−IDMS Standardized mg/dL

Mean −− 0.811 −− −− −− 6.20
SD
CV
1 −−
−−
0.346
42.7
2 −−
−−
−−
−−
3 −−
−−
2.04
32.9
# Points −− 12 −− −− −− 12
# Labs 2 2
VITROS Microslide Series • Dual Slide

Mean −− 0.675 −− 1.76 −− −−
SD
CV
1 −−
−−
0.032
4.8
2 −−
−−
0.040
2.3
3 −−
−−
−−
−−
# Points −− 31 −− 31 −− −−
# Labs 2 2

Mean 0.735 0.743 1.82 1.83 7.19 7.15
SD
CV
1 0.039
5.4
0.043
5.8
2 0.040
2.2
0.094
5.1
3 0.146
2.0
0.254
3.5
# Points 193 4881 142 3011 173 4425
# Labs 11 65 10 37 7 45

Mean 0.730 0.757 1.76 1.80 7.09 7.14
SD
CV
1 0.039
5.4
0.032
4.2
2 0.058
3.3
0.057
3.2
3 0.184
2.6
0.195
2.7
# Points 92 2399 92 1184 92 2300
# Labs 5 31 5 15 5 28

Mean 0.719 0.746 1.80 1.79 7.12 7.34
SD
CV
1 0.027
3.8
0.036
4.9
2 0.068
3.8
0.073
4.0
3 0.137
1.9
0.228
3.1
# Points 126 906 81 588 42 660
# Labs 6 21 4 12 2 15

Mean 0.745 0.745 1.83 1.83 7.25 7.19
SD
CV
1 0.021
2.9
0.024
3.2
2 0.059
3.2
0.055
3.0
3 0.285
3.9
0.250
3.5
# Points 84 792 104 766 104 769
# Labs 2 2 2 2 2 2

Mean −− 0.745 −− −− −− 6.84
SD
CV
1 −−
−−
0.019
2.5
2 −−
−−
−−
−−
3 −−
−−
0.089
1.3
# Points −− 113 −− −− −− 112
# Labs 1 1

Mean 0.787 0.775 1.88 1.86 7.23 7.32
SD
CV
1 0.029
3.7
0.029
3.8
2 0.080
4.3
0.065
3.5
3 0.153
2.1
0.185
2.5
# Points 55 212 20 57 56 213
# Labs 3 8 1 4 3 8

Mean 0.734 0.733 1.74 1.74 7.26 7.00
SD
CV
1 0.050
6.8
0.032
4.4
2 0.090
5.2
0.079
4.5
3 0.176
2.4
0.271
3.9
# Points 31 178 13 17 31 177
# Labs 2 4 1 2 2 4

Mean 0.774 0.774 1.73 1.73 7.29 7.29
SD
CV
1 0.037
4.8
0.037
4.8
2 0.043
2.5
0.043
2.5
3 0.183
2.5
0.183
2.5
# Points 53 53 21 21 53 53
# Labs 3 3 1 1 3 3

Mean −− 0.742 −− −− −− 6.94
SD
CV
1 −−
−−
0.016
2.2
2 −−
−−
−−
−−
3 −−
−−
0.144
2.1
# Points −− 499 −− −− −− 497
# Labs 4 4

Mean 0.760 0.761 1.77 1.77 −− 7.19
SD
CV
1 0.015
1.9
0.035
4.6
2 0.040
2.3
0.057
3.2
3 −−
−−
0.239
3.3
# Points 76 3856 76 2734 −− 3228
# Labs 2 26 2 18 24

Mean −− 0.741 −− 1.75 −− 7.08
SD
CV
1 −−
−−
0.042
5.7
2 −−
−−
0.058
3.3
3 −−
−−
0.216
3.1
# Points −− 3082 −− 1504 −− 3062
# Labs 21 13 21

Mean 0.797 0.765 −− 1.78 7.12 7.11
SD
CV
1 0.027
3.4
0.038
4.9
2 −−
−−
0.068
3.8
3 0.106
1.5
0.218
3.1
# Points 48 2512 −− 987 44 2473
# Labs 2 19 13 2 20

Mean 0.791 0.782 1.74 1.76 7.11 7.16
SD
CV
1 0.030
3.8
0.028
3.6
2 0.039
2.2
0.034
1.9
3 0.555
7.8
0.257
3.6
# Points 222 3408 65 1189 201 3308
# Labs 10 17 4 9 10 15

Mean 0.803 0.805 1.80 1.82 7.07 7.11
SD
CV
1 0.024
2.9
0.035
4.3
2 0.096
5.3
0.082
4.5
3 0.832
11.8
0.476
6.7
# Points 82 180 61 94 29 93
# Labs 7 9 5 5 4 6

Mean −− 0.774 −− 1.93 −− 7.16
SD
CV
1 −−
−−
0.026
3.3
2 −−
−−
0.052
2.7
3 −−
−−
0.171
2.4
# Points −− 633 −− 319 −− 658
# Labs 4 2 4

Mean 0.725 0.724 1.74 1.77 −− −−
SD
CV
1 0.020
2.7
0.022
3.0
2 0.051
3.0
0.056
3.1
3 −−
−−
−−
−−
# Points 50 302 49 300 −− −−
# Labs 2 2 2 2

Mean −− 0.790 −− 1.93 −− 7.19
SD
CV
1 −−
−−
0.013
1.7
2 −−
−−
0.028
1.4
3 −−
−−
0.077
1.1
# Points −− 127 −− 123 −− 126
# Labs 1 1 1

Mean −− 0.813 −− 1.89 −− 7.16
SD
CV
1 −−
−−
0.195
24.0
2 −−
−−
0.042
2.2
3 −−
−−
0.155
2.2
# Points −− 704 −− 253 −− 700
# Labs 4 1 4

Mean −− 0.772 −− −− −− 7.13
SD
CV
1 −−
−−
0.023
3.0
2 −−
−−
−−
−−
3 −−
−−
0.171
2.4
# Points −− 137 −− −− −− 135
# Labs 2 3

Mean 0.690 0.746 −− 1.80 6.95 7.15
SD
CV
1 0.010
1.4
0.031
4.2
2 −−
−−
0.063
3.5
3 0.110
1.6
0.283
4.0
# Points 8 8450 −− 2780 8 8425
# Labs 1 66 21 1 64

Mean −− 0.810 −− −− −− 7.17
SD
CV
1 −−
−−
0.023
2.8
2 −−
−−
−−
−−
3 −−
−−
0.123
1.7
# Points −− 163 −− −− −− 163
# Labs 3 3

Mean −− 0.775 −− −− −− 7.14
SD
CV
1 −−
−−
0.019
2.5
2 −−
−−
−−
−−
3 −−
−−
0.225
3.2
# Points −− 276 −− −− −− 277
# Labs 1 1

Mean −− 0.758 −− 1.82 −− 7.02
SD
CV
1 −−
−−
0.032
4.2
2 −−
−−
0.098
5.4
3 −−
−−
0.212
3.0
# Points −− 1840 −− 558 −− 1316
# Labs 14 4 12

Mean −− 0.751 −− 1.67 −− 6.85
SD
CV
1 −−
−−
0.021
2.8
2 −−
−−
0.065
3.9
3 −−
−−
0.180
2.6
# Points −− 662 −− 96 −− 628
# Labs 6 1 6

Mean −− 0.756 −− 1.80 −− 7.24
SD
CV
1 −−
−−
0.030
4.0
2 −−
−−
0.056
3.1
3 −−
−−
0.211
2.9
# Points −− 4121 −− 3142 −− 4770
# Labs 25 19 26

Mean −− 0.755 −− 1.77 −− 7.09
SD
CV
1 −−
−−
0.029
3.8
2 −−
−−
0.058
3.3
3 −−
−−
0.201
2.8
# Points −− 6912 −− 3725 −− 7320
# Labs 61 28 59

Mean −− 0.763 −− 1.80 −− 7.11
SD
CV
1 −−
−−
0.030
4.0
2 −−
−−
0.039
2.2
3 −−
−−
0.160
2.2
# Points −− 2758 −− 1221 −− 2337
# Labs 37 14 32

Mean −− 0.733 −− 1.73 −− 7.05
SD
CV
1 −−
−−
0.032
4.4
2 −−
−−
0.034
2.0
3 −−
−−
0.176
2.5
# Points −− 1035 −− 55 −− 1039
# Labs 10 1 10

Mean −− 0.763 −− 1.81 −− 7.13
SD
CV
1 −−
−−
0.032
4.2
2 −−
−−
0.093
5.1
3 −−
−−
0.231
3.2
# Points −− 11170 −− 3560 −− 10555
# Labs 76 26 72

Mean −− 0.774 −− 1.82 −− 7.18
SD
CV
1 −−
−−
0.041
5.3
2 −−
−−
0.061
3.3
3 −−
−−
0.300
4.2
# Points −− 1235 −− 397 −− 1206
# Labs 19 8 18

Mean 0.744 0.742 1.82 1.82 7.24 7.24
SD
CV
1 0.034
4.6
0.035
4.8
2 0.046
2.5
0.076
4.2
3 0.211
2.9
0.252
3.5
# Points 677 9686 214 3142 602 9019
# Labs 30 86 13 36 26 73

Mean 0.760 0.744 1.80 1.83 7.30 7.35
SD
CV
1 0.026
3.4
0.030
4.0
2 0.040
2.2
0.050
2.8
3 0.164
2.2
0.233
3.2
# Points 41 5989 22 1949 41 5562
# Labs 2 50 1 17 2 42

Mean −− 0.756 −− 1.86 −− 7.31
SD
CV
1 −−
−−
0.026
3.4
2 −−
−−
0.027
1.4
3 −−
−−
0.289
4.0
# Points −− 455 −− 104 −− 458
# Labs 5 2 6

Mean −− 0.710 −− −− −− 7.25
SD
CV
1 −−
−−
0.020
2.8
2 −−
−−
−−
−−
3 −−
−−
0.095
1.3
# Points −− 73 −− −− −− 25
# Labs 1 1

Mean −− 0.578 −− −− −− 6.98
SD
CV
1 −−
−−
0.010
1.7
2 −−
−−
−−
−−
3 −−
−−
0.053
0.8
# Points −− 6 −− −− −− 6
# Labs 1 1

Mean −− 0.619 −− −− −− 6.80
SD
CV
1 −−
−−
0.011
1.8
2 −−
−−
−−
−−
3 −−
−−
0.065
1.0
# Points −− 15 −− −− −− 15
# Labs 1 1

Mean −− 0.623 −− −− −− 7.16
SD
CV
1 −−
−−
0.009
1.5
2 −−
−−
−−
−−
3 −−
−−
0.122
1.7
# Points −− 44 −− −− −− 45
# Labs 1 1

Mean −− 0.608 −− −− −− 7.22
SD
CV
1 −−
−−
0.020
3.2
2 −−
−−
−−
−−
3 −−
−−
0.082
1.1
# Points −− 72 −− −− −− 69
# Labs 1 1

Mean −− 0.580 −− −− −− 7.41
SD
CV
1 −−
−−
0.009
1.5
2 −−
−−
−−
−−
3 −−
−−
0.074
1.0
# Points −− 6 −− −− −− 6
# Labs 1 1

Mean −− 0.611 −− −− −− 7.37
SD
CV
1 −−
−−
0.018
3.0
2 −−
−−
−−
−−
3 −−
−−
0.123
1.7
# Points −− 107 −− −− −− 131
# Labs 1 1

Mean −− 0.640 −− −− −− 7.42
SD
CV
1 −−
−−
0.012
1.9
2 −−
−−
−−
−−
3 −−
−−
0.089
1.2
# Points −− 69 −− −− −− 66
# Labs 1 1

Mean −− 0.724 −− −− −− 7.04
SD
CV
1 −−
−−
0.011
1.5
2 −−
−−
−−
−−
3 −−
−−
0.082
1.2
# Points −− 134 −− −− −− 123
# Labs 2 2

Mean −− 0.709 −− −− −− 7.14
SD
CV
1 −−
−−
0.017
2.4
2 −−
−−
−−
−−
3 −−
−−
0.181
2.5
# Points −− 42 −− −− −− 44
# Labs 1 1
Method Group • Enzymatic−VITROS, IFCC−IDMS Standardized

Mean 0.752 0.754 1.80 1.80 7.20 7.17
SD
CV
1 0.040
5.4
0.041
5.4
0.065
3.6
2 0.073
4.1
3 0.304
4.2
0.249
3.5
# Points 1838 79637 960 33532 1476 76117
# Labs 88 713 51 315 69 642
Creatinine Immunoturbidimetric mg/dL

Mindray BS Series
Mean −− 0.848 −− 6.65 −− −−
SD
CV
1 −−
−−
0.039
4.6
2 −−
−−
0.285
4.3
3 −−
−−
−−
−−
# Points −− 226 −− 225 −− −−
# Labs 1 1

Mean −− 0.848 −− 6.65 −− −−
SD
CV
1 −−
−−
0.039
4.6
2 −−
−−
0.285
4.3
3 −−
−−
−−
−−
# Points −− 226 −− 225 −− −−
# Labs 1 1
Digoxin Affinity Column ng/mL

Mean −− 0.416 −− −− −− 2.83
SD
CV
1 −−
−−
0.095
22.9
2 −−
−−
−−
−−
3 −−
−−
0.140
5.0
# Points −− 255 −− −− −− 255
# Labs 1 1
Method Group • Affinity Column

Mean −− 0.416 −− −− −− 2.83
SD
CV
1 −−
−−
0.095
22.9
2 −−
−−
−−
−−
3 −−
−−
0.140
5.0
# Points −− 255 −− −− −− 255
# Labs 1 1
Digoxin Chemiluminescence ng/mL

Beckman Coulter UniCel DxI Series
Mean 0.570 0.570 1.53 1.53 −− −−
SD
CV
1 0.050
8.8
0.050
8.8
2 0.100
6.5
0.100
6.5
3 −−
−−
−−
−−
# Points 26 26 26 26 −− −−
# Labs 1 1 1 1

Mean 0.449 0.463 1.82 1.85 3.09 3.10
SD
CV
1 0.024
5.2
0.027
5.9
2 0.045
2.5
0.043
2.3
3 0.066
2.1
0.073
2.3
# Points 803 46574 310 14829 610 40688
# Labs 20 94 8 25 18 86

Mean 0.453 0.463 1.80 1.85 3.09 3.10
SD
CV
1 0.032
7.2
0.028
6.0
2 0.093
5.2
0.045
2.4
3 0.066
2.1
0.073
2.3
# Points 829 46600 336 14855 610 40688
# Labs 21 95 9 26 18 86
Digoxin EIA ng/mL

Mean 0.446 0.473 1.69 1.73 2.79 2.90
SD
CV
1 0.057
12.9
0.086
18.2
2 0.092
5.4
0.110
6.4
3 0.140
5.0
0.196
6.8
# Points 76 4437 51 1375 77 4421
# Labs 3 17 2 6 3 14
Beckman Coulter AU Series • Emit 2000 Digoxin, REF OSR4H229

Mean −− 0.492 −− 1.81 −− 2.95
SD
CV
1 −−
−−
0.096
19.5
−−
−−
2 0.153
8.4
3 −−
−−
0.220
7.5
# Points −− 971 −− 421 −− 984
# Labs 8 2 8

Mean 0.438 0.421 −− 1.76 2.81 2.80
SD
CV
1 0.075
17.1
0.082
19.4
2 −−
−−
0.110
6.3
3 0.103
3.7
0.131
4.7
# Points 164 10613 −− 483 163 10056
# Labs 6 35 3 6 34

Mean 0.457 0.463 1.80 1.84 3.10 3.11
SD
CV
1 0.021
4.6
0.029
6.3
2 0.023
1.3
0.053
2.9
3 0.073
2.4
0.072
2.3
# Points 43 14978 10 6265 45 12870
# Labs 3 39 2 16 3 36
Digoxin EIA ng/mL

Mean −− 0.688 −− 1.20 −− 1.81
SD
CV
1 −−
−−
0.112
16.4
2 −−
−−
0.069
5.7
3 −−
−−
0.053
2.9
# Points −− 33 −− 28 −− 27
# Labs 1 1 1

Mean −− 0.576 −− 1.17 −− 1.92
SD
CV
1 −−
−−
0.090
15.6
2 −−
−−
0.050
4.3
3 −−
−−
0.192
10.0
# Points −− 229 −− 190 −− 224
# Labs 2 1 2

Mean −− 0.593 −− 1.18 −− 2.14
SD
CV
1 −−
−−
0.102
17.2
2 −−
−−
0.064
5.4
3 −−
−−
0.260
12.1
# Points −− 207 −− 100 −− 190
# Labs 2 1 2

Mean −− 0.642 −− 1.45 −− 2.41
SD
CV
1 −−
−−
0.094
14.6
2 −−
−−
0.048
3.3
3 −−
−−
0.154
6.4
# Points −− 356 −− 95 −− 326
# Labs 2 1 2

Mean −− 0.586 −− 1.44 −− 2.32
SD
CV
1 −−
−−
0.074
12.6
2 −−
−−
0.069
4.8
3 −−
−−
0.198
8.5
# Points −− 234 −− 140 −− 243
# Labs 2 1 2

Mean −− 0.612 −− 1.42 −− 2.56
SD
CV
1 −−
−−
0.078
12.8
2 −−
−−
0.075
5.3
3 −−
−−
0.194
7.6
# Points −− 291 −− 93 −− 255
# Labs 2 1 2

Mean −− 0.664 −− 1.51 −− 2.57
SD
CV
1 −−
−−
0.066
9.9
2 −−
−−
0.074
4.9
3 −−
−−
0.124
4.8
# Points −− 177 −− 26 −− 156
# Labs 2 1 2

Mean −− 0.604 −− 1.58 −− 2.28
SD
CV
1 −−
−−
0.087
14.4
2 −−
−−
0.102
6.4
3 −−
−−
0.183
8.0
# Points −− 159 −− 33 −− 143
# Labs 4 3 4

Mean −− 0.619 −− 1.51 −− 2.47
SD
CV
1 −−
−−
0.118
19.1
2 −−
−−
0.082
5.4
3 −−
−−
0.206
8.3
# Points −− 889 −− 252 −− 844
# Labs 15 8 13

Mean −− 0.701 −− 1.57 −− 2.51
SD
CV
1 −−
−−
0.102
14.6
2 −−
−−
0.075
4.8
3 −−
−−
0.140
5.6
# Points −− 346 −− 451 −− 499
# Labs 8 8 7
Digoxin EIA ng/mL

Mean −− 0.630 −− 1.59 −− 2.57
SD
CV
1 −−
−−
0.115
18.2
2 −−
−−
0.072
4.5
3 −−
−−
0.141
5.5
# Points −− 528 −− 315 −− 419
# Labs 6 5 4

Mean −− 0.811 −− 1.52 −− 2.52
SD
CV
1 −−
−−
0.552
68.0
2 −−
−−
0.111
7.3
3 −−
−−
0.212
8.4
# Points −− 377 −− 611 −− 545
# Labs 7 5 6

Mean −− 0.644 −− 1.46 −− 2.53
SD
CV
1 −−
−−
0.102
15.9
2 −−
−−
0.103
7.1
3 −−
−−
0.257
10.1
# Points −− 219 −− 223 −− 216
# Labs 7 6 7

Mean 0.540 0.552 −− 1.41 2.68 2.68
SD
CV
1 0.062
11.5
0.056
10.1
2 −−
−−
0.116
8.2
3 0.223
8.3
0.235
8.8
# Points 32 311 −− 117 32 213
# Labs 1 7 3 1 7

Mean 0.524 0.526 1.38 1.42 2.39 2.39
SD
CV
1 0.064
12.3
0.065
12.4
2 0.043
3.1
0.066
4.6
3 0.119
5.0
0.117
4.9
# Points 30 189 16 308 15 249
# Labs 3 4 1 3 2 4

Mean 0.652 0.584 1.46 1.46 2.54 2.49
SD
CV
1 0.158
24.2
0.138
23.6
2 0.075
5.2
0.075
5.2
3 0.167
6.6
0.137
5.5
# Points 35 67 24 24 24 55
# Labs 3 4 2 2 2 3

Mean 0.477 0.475 1.60 1.72 2.80 2.89
SD
CV
1 0.101
21.2
0.113
23.8
2 0.161
10.1
0.183
10.6
3 0.202
7.2
0.269
9.3
# Points 380 35700 101 11606 356 32935
# Labs 19 174 7 78 17 160
Digoxin Electrochemiluminescence (ECL) ng/mL

Mean −− 0.558 −− −− −− 2.80
SD
CV
1 −−
−−
0.128
23.0
2 −−
−−
−−
−−
3 −−
−−
0.138
4.9
# Points −− 1009 −− −− −− 908
# Labs 2 2
Method Group • Electrochemiluminescence (ECL)

Mean −− 0.558 −− −− −− 2.80
SD
CV
1 −−
−−
0.128
23.0
2 −−
−−
−−
−−
3 −−
−−
0.138
4.9
# Points −− 1009 −− −− −− 908
# Labs 2 2
Digoxin Immunonephelometric, kinetic ng/mL

Mean −− 0.441 −− −− −− 2.81
SD
CV
1 −−
−−
0.068
15.4
2 −−
−−
−−
−−
3 −−
−−
0.127
4.5
# Points −− 91 −− −− −− 89
# Labs 1 1

Mean −− 0.441 −− −− −− 2.81
SD
CV
1 −−
−−
0.068
15.4
2 −−
−−
−−
−−
3 −−
−−
0.127
4.5
# Points −− 91 −− −− −− 89
# Labs 1 1
Digoxin Immunoturbidimetric ng/mL

Mean 0.357 0.347 1.73 1.64 2.79 2.80
SD
CV
1 0.084
23.5
0.066
19.1
2 0.093
5.4
0.093
5.7
3 0.086
3.1
0.166
5.9
# Points 82 2669 71 2310 48 2258
# Labs 3 18 4 14 2 11

Mean 0.460 0.479 −− 1.75 2.79 2.94
SD
CV
1 0.060
13.0
0.083
17.2
2 −−
−−
0.155
8.8
3 0.130
4.7
0.182
6.2
# Points 31 2540 −− 770 31 2578
# Labs 1 5 2 1 5

Mean −− −− −− 1.83 −− 3.20
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.028
1.5
3 −−
−−
0.042
1.3
# Points −− −− −− 7 −− 7
# Labs 1 1

Mean −− 0.423 −− 1.49 −− 2.82
SD
CV
1 −−
−−
0.092
21.7
2 −−
−−
0.168
11.3
3 −−
−−
0.141
5.0
# Points −− 2690 −− 263 −− 2831
# Labs 11 4 11

Mean −− 0.341 −− −− −− −−
SD
CV
1 −−
−−
0.052
15.2
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 61 −− −− −− −−
# Labs 1

Mean −− 0.359 −− 1.66 −− 2.87
SD
CV
1 −−
−−
0.051
14.3
2 −−
−−
0.070
4.2
3 −−
−−
0.122
4.3
# Points −− 1127 −− 379 −− 1086
# Labs 3 2 2

Mean −− 0.331 −− 1.60 −− 2.82
SD
CV
1 −−
−−
0.056
16.9
2 −−
−−
0.110
6.8
3 −−
−−
0.110
3.9
# Points −− 1709 −− 105 −− 1622
# Labs 6 2 3

Mean 0.385 0.396 1.73 1.65 2.79 2.85
SD
CV
1 0.090
23.5
0.094
23.7
2 0.093
5.4
0.130
7.9
3 0.105
3.8
0.161
5.6
# Points 113 10815 71 3834 79 10401
# Labs 4 45 4 25 3 34
Digoxin KIMS (Roche) ng/mL

Mean 0.550 0.527 1.79 1.77 2.95 2.86
SD
CV
1 0.094
17.0
0.099
18.8
2 0.089
5.0
0.104
5.8
3 0.104
3.5
0.142
5.0
# Points 439 5129 31 925 441 5120
# Labs 6 11 1 4 6 11

Mean 0.537 0.547 1.76 1.80 2.85 2.91
SD
CV
1 0.054
10.1
0.068
12.4
2 0.043
2.4
0.088
4.9
3 0.031
1.1
0.093
3.2
# Points 27 912 26 926 28 959
# Labs 1 3 1 3 1 3
Roche cobas c 303/503 • Roche DIG, REF 08057613

Mean −− 0.594 −− 1.83 −− 2.95
SD
CV
1 −−
−−
0.066
11.0
2 −−
−−
0.043
2.3
3 −−
−−
0.087
2.9
# Points −− 1320 −− 373 −− 1324
# Labs 4 1 4

Mean 0.549 0.541 1.77 1.79 2.94 2.88
SD
CV
1 0.092
16.7
0.094
17.4
2 0.073
4.1
0.092
5.1
3 0.103
3.5
0.133
4.6
# Points 466 7361 57 2224 469 7403
# Labs 7 18 2 8 7 18
Ethanol (Alcohol) Chemiluminescence mg/dL

Mean 21.10 21.34 80.76 81.04 −− 21.50
SD
CV
1 0.289
1.4
0.590
2.8
2 0.294
0.4
1.62
2.0
3 −−
−−
0.000
0.0
# Points 7 61 7 60 −− 1
# Labs 1 1 1 1 1
Beckman Coulter Access, LXi 725, DxC 600i IA Systems

Mean 24.70 22.27 −− −− 210.9 197.6
SD
CV
1 2.05
8.3
3.09
13.9
2 −−
−−
−−
−−
3 9.10
4.3
11.01
5.6
# Points 26 766 −− −− 30 751
# Labs 1 1 1 1

Mean 23.94 22.21 80.76 81.04 210.9 197.6
SD
CV
1 2.35
9.8
2.99
13.5
2 0.294
0.4
1.62
2.0
3 9.10
4.3
11.01
5.6
# Points 33 827 7 60 30 751
# Labs 2 2 1 1 1 1
Ethanol (Alcohol) EIA mg/dL

Mean −− 23.31 −− 82.69 −− 207.1
SD
CV
1 −−
−−
2.13
9.2
2 −−
−−
3.76
4.5
3 −−
−−
6.87
3.3
# Points −− 265 −− 347 −− 230
# Labs 2 2 1

Mean −− 23.31 −− 82.69 −− 207.1
SD
CV
1 −−
−−
2.13
9.2
2 −−
−−
3.76
4.5
3 −−
−−
6.87
3.3
# Points −− 265 −− 347 −− 230
# Labs 2 2 1
Ethanol (Alcohol) Enzymatic UV mg/dL

Mean 22.89 22.65 81.18 82.72 201.8 202.4
SD
CV
1 2.07
9.1
2.00
8.8
2 4.05
5.0
3.65
4.4
3 5.85
2.9
6.40
3.2
# Points 35 5282 19 3457 13 5210
# Labs 2 32 2 21 1 31

Mean 23.53 22.56 85.50 81.32 201.3 200.7
SD
CV
1 3.82
16.2
2.59
11.5
2 6.53
7.6
5.38
6.6
3 15.38
7.6
11.13
5.5
# Points 185 5291 68 2063 197 5991
# Labs 6 14 2 4 6 15
Beckman Coulter AU Series • Emit II Plus Ethyl Alcohol, REF OSR9K229

Mean −− 21.68 −− 78.02 −− 55.29
SD
CV
1 −−
−−
2.89
13.3
2
−−
−−
7.74
9.9
3 −−
−−
82.22
148.7
# Points −− 344 −− 170 −− 1537
# Labs 4 2 7

Mean −− 19.68 −− 69.32 −− 183.5
SD
CV
1 −−
−−
1.79
9.1
2 −−
−−
5.40
7.8
3 −−
−−
10.17
5.5
# Points −− 1294 −− 57 −− 1246
# Labs 8 3 7

Mean 20.90 17.68 −− 78.56 192.7 165.8
SD
CV
1 1.10
5.3
7.54
42.6
2 −−
−−
3.04
3.9
3 6.60
3.4
69.15
41.7
# Points 242 8890 −− 3686 243 8856
# Labs 1 25 9 1 25

Mean −− 20.18 −− 75.97 −− 189.2
SD
CV
1 −−
−−
1.16
5.8
2 −−
−−
3.18
4.2
3 −−
−−
7.32
3.9
# Points −− 1523 −− 1113 −− 1542
# Labs 6 2 6
Roche cobas c 303/503 • Roche ETOH2, REF 08057630/08445672

Mean −− 23.42 −− 76.98 −− 185.0
SD
CV
1 −−
−−
3.45
14.7
−−
−−
2 4.38
5.7
3 −−
−−
6.14
3.3
# Points −− 182 −− 339 −− 328
# Labs 1 1 1

Mean −− −− −− −− −− 198.4
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− −− −− −− −− 1
# Labs 1

Mean −− 23.01 −− 86.37 −− 216.9
SD
CV
1 −−
−−
1.22
5.3
2 −−
−−
2.42
2.8
3 −−
−−
5.71
2.6
# Points −− 5524 −− 5257 −− 5504
# Labs 5 5 5

Mean −− 21.83 −− 81.57 −− 198.9
SD
CV
1 −−
−−
2.28
10.4
2 −−
−−
5.16
6.3
3 −−
−−
11.53
5.8
# Points −− 8976 −− 987 −− 7977
# Labs 16 1 14
Ethanol (Alcohol) Enzymatic UV mg/dL

Mean 21.15 21.13 −− 78.23 196.8 200.8
SD
CV
1 2.00
9.4
2.14
10.1
2 −−
−−
7.68
9.8
3 7.92
4.0
5.07
2.5
# Points 249 16568 −− 744 250 328K
# Labs 11 44 6 11 40

Mean 21.52 22.06 83.52 83.49 206.7 210.0
SD
CV
1 1.80
8.4
2.28
10.3
2 3.99
4.8
3.67
4.4
3 6.61
3.2
7.49
3.6
# Points 287 25850 96 5894 334 29471
# Labs 9 75 3 14 12 77
Method Group • Enzymatic UV

Mean 21.70 21.42 84.02 82.30 199.9 200.2
SD
CV
1 2.45
11.3
3.56
16.6
2 5.24
6.2
4.93
6.0
3 10.68
5.3
16.91
8.4
# Points 998 79724 183 23767 1037 396K
# Labs 29 230 7 68 31 229
Ethanol (Alcohol) Enzymatic UV−VITROS mg/dL

Mean −− 20.48 −− 77.89 −− 205.4
SD
CV
1 −−
−−
1.18
5.8
2 −−
−−
5.26
6.7
3 −−
−−
9.99
4.9
# Points −− 6759 −− 544 −− 6692
# Labs 25 8 24

Mean 20.38 20.50 78.71 78.80 208.9 207.4
SD
CV
1 0.699
3.4
0.977
4.8
2 4.09
5.2
3.60
4.6
3 8.63
4.1
10.45
5.0
# Points 109 4743 28 790 107 4543
# Labs 7 25 2 7 6 23

Mean 19.66 18.96 79.48 79.48 211.1 207.5
SD
CV
1 0.484
2.5
1.17
6.1
2 1.19
1.5
1.19
1.5
3 8.67
4.1
9.24
4.5
# Points 93 471 6 6 87 459
# Labs 6 6 1 1 5 5
Method Group • Enzymatic UV−VITROS

Mean 20.05 20.43 78.85 78.43 209.9 206.3
SD
CV
1 0.705
3.5
1.14
5.6
2 3.74
4.7
4.28
5.5
3 8.69
4.1
10.19
4.9
# Points 202 11973 34 1331 194 11694
# Labs 13 56 3 15 11 52
Ethanol (Alcohol) Enzymatic, colorimetric mg/dL

Mean 20.06 20.91 −− −− 193.4 198.8
SD
CV
1 1.67
8.3
1.76
8.4
2 −−
−−
−−
−−
3 13.62
7.0
9.72
4.9
# Points 34 859 −− −− 34 840
# Labs 1 1 1 1

Mean −− 21.40 −− −− −− 197.4
SD
CV
1 −−
−−
2.83
13.2
2 −−
−−
−−
−−
3 −−
−−
12.48
6.3
# Points −− 98 −− −− −− 98
# Labs 1 1
Ethanol (Alcohol) Enzymatic, colorimetric mg/dL

Mean 20.27 21.18 −− −− 186.6 191.5
SD
CV
1 0.900
4.4
1.22
5.7
2 −−
−−
−−
−−
3 4.44
2.4
6.43
3.4
# Points 90 191 −− −− 90 268
# Labs 1 1 1 1

Mean −− 21.15 −− −− −− 194.4
SD
CV
1 −−
−−
2.12
10.0
2 −−
−−
−−
−−
3 −−
−−
7.48
3.8
# Points −− 2152 −− −− −− 1393
# Labs 2 2

Mean −− 20.38 −− −− −− 197.7
SD
CV
1 −−
−−
0.860
4.2
2 −−
−−
−−
−−
3 −−
−−
10.51
5.3
# Points −− 215 −− −− −− 220
# Labs 2 2

Mean 20.21 21.05 −− −− 188.4 195.8
SD
CV
1 1.16
5.7
1.98
9.4
2 −−
−−
−−
−−
3 8.56
4.5
8.92
4.6
# Points 124 3515 −− −− 124 2819
# Labs 2 7 2 7
Ferritin Chemiluminescence ng/mL

Mean −− 80.43 −− 770.9 −− −−
SD
CV
1 −−
−−
3.20
4.0
2 −−
−−
19.54
2.5
3 −−
−−
−−
−−
# Points −− 7 −− 5 −− −−
# Labs 1 1
Beckman Coulter UniCel DxI Series

Mean −− 33.31 −− 46.60 −− 53.97
SD
CV
1 −−
−−
2.06
6.2
2 −−
−−
2.67
5.7
3 −−
−−
3.23
6.0
# Points −− 340 −− 342 −− 337
# Labs 1 1 1
Siemens Atellica IM Analyzer

Mean 32.81 33.67 44.76 45.67 −− −−
SD
CV
1 1.54
4.7
1.95
5.8
2 1.50
3.4
2.02
4.4
3 −−
−−
−−
−−
# Points 64 94 64 94 −− −−
# Labs 1 1 1 1

Mean 38.13 39.34 53.43 54.96 62.38 63.42
SD
CV
1 1.31
3.4
1.09
2.8
2 1.16
2.2
1.80
3.3
3 1.35
2.2
1.78
2.8
# Points 157 11202 68 4603 148 8553
# Labs 5 39 2 14 5 33

Mean 36.59 39.14 49.22 54.93 62.38 63.06
SD
CV
1 2.78
7.6
1.90
4.8
2 4.55
9.2
22.77
41.4
3 1.35
2.2
2.59
4.1
# Points 221 11643 132 5044 148 8890
# Labs 6 42 3 17 5 34
Ferritin EIA ng/mL

Mean 54.30 52.30 73.05 69.16 −− 79.46
SD
CV
1 0.880
1.6
2.11
4.0
2 1.13
1.5
2.54
3.7
3 −−
−−
3.17
4.0
# Points 19 4330 19 2536 −− 2013
# Labs 1 15 1 10 9

Mean 54.30 52.30 73.05 69.16 −− 79.46
SD
CV
1 0.880
1.6
2.11
4.0
2 1.13
1.5
2.54
3.7
3 −−
−−
3.17
4.0
# Points 19 4330 19 2536 −− 2013
# Labs 1 15 1 10 9
Ferritin Immunoturbidimetric ng/mL

Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCHITECT Quantia Ferritin (6K41)
Mean −− 57.61 −− −− −− 77.98
SD
CV
1 −−
−−
2.33
4.0
2
−−
−−
−−
−−
3 −−
−−
2.14
2.7
# Points −− 106 −− −− −− 103
# Labs 1 1

Mean −− 47.71 −− 66.12 −− 77.26
SD
CV
1 −−
−−
2.18
4.6
2 −−
−−
2.72
4.1
3 −−
−−
3.28
4.2
# Points −− 1457 −− 1543 −− 1513
# Labs 4 4 4

Mean −− 59.92 −− −− −− 99.25
SD
CV
1 −−
−−
2.81
4.7
2 −−
−−
−−
−−
3 −−
−−
3.18
3.2
# Points −− 37 −− −− −− 36
# Labs 1 1
Roche cobas 6000/8000/c 311 • Alternate Calibration

Mean 57.92 57.95 −− −− 95.13 95.89
SD
CV
1 0.880
1.5
1.21
2.1
2 −−
−−
−−
−−
3 1.30
1.4
1.55
1.6
# Points 45 942 −− −− 45 941
# Labs 2 2 2 2

Mean −− 48.65 −− 66.12 −− 77.78
SD
CV
1 −−
−−
3.73
7.7
2 −−
−−
2.72
4.1
3 −−
−−
4.54
5.8
# Points −− 1600 −− 1543 −− 1652
# Labs 6 4 6
Gamma Globulin Agarose Gel %

Interlab G26
Mean −− 13.43 −− 14.90 −− 15.77
SD
CV
1 −−
−−
0.940
7.0
2 −−
−−
0.700
4.7
3 −−
−−
1.69
10.7
# Points −− 4 −− 4 −− 4
# Labs 1 1 1

Mean −− 13.43 −− 14.90 −− 15.77
SD
CV
1 −−
−−
0.940
7.0
2 −−
−−
0.700
4.7
3 −−
−−
1.69
10.7
# Points −− 4 −− 4 −− 4
# Labs 1 1 1
Gamma Globulin REP Gel %

Helena REP
Mean −− −− −− 15.14 −− 2.00
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.24
8.2
3 −−
−−
0.000
0.0
# Points −− −− −− 91 −− 1
# Labs 1 1

Mean −− −− −− 15.14 −− 2.00
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.24
8.2
3 −−
−−
0.000
0.0
# Points −− −− −− 91 −− 1
# Labs 1 1
Gentamicin Chemiluminescence µg/mL

Beckman Coulter AU Series • Emit 2000 Gentamicin Plus, REF OSR4T229
Mean −− −− −− 5.66 −− 8.29
SD
CV
1 −−
−−
−−
−−
−−
−−
2
0.710
12.5
3 −−
−−
0.490
5.9
# Points −− −− −− 30 −− 23
# Labs 1 1

Mean −− 1.79 −− −− −− 9.04
SD
CV
1 −−
−−
0.075
4.2
2 −−
−−
−−
−−
3 −−
−−
0.195
2.2
# Points −− 273 −− −− −− 273
# Labs 1 1

Mean −− 1.79 −− 5.66 −− 8.99
SD
CV
1 −−
−−
0.075
4.2
2 −−
−−
0.710
12.5
3 −−
−−
0.306
3.4
# Points −− 273 −− 30 −− 296
# Labs 1 1 2
Gentamicin EIA µg/mL

Mean −− 1.95 −− 5.10 −− 9.57
SD
CV
1 −−
−−
0.129
6.6
2 −−
−−
0.000
0.0
3 −−
−−
0.693
7.2
# Points −− 815 −− 1 −− 707
# Labs 3 1 3
Beckman Coulter AU Series • Emit 2000 Gentamicin Plus, REF OSR4T229

Mean 1.94 1.93 −− 5.46 9.67 9.20
SD
CV
1 0.085
4.4
0.156
8.1
−−
−−
2
0.563
10.3
3 0.595
6.2
0.835
9.1
# Points 31 700 −− 289 32 718
# Labs 1 4 1 1 4
Roche cobas c 303/503 • Roche GENT2, REF 08057770

Mean −− 2.09 −− −− −− 8.06
SD
CV
1 −−
−−
0.073
3.5
2 −−
−−
−−
−−
3 −−
−−
0.264
3.3
# Points −− 10 −− −− −− 11
# Labs 1 1

Mean −− 1.75 −− −− −− 8.30
SD
CV
1 −−
−−
0.152
8.7
2 −−
−−
−−
−−
3 −−
−−
0.599
7.2
# Points −− 437 −− −− −− 432
# Labs 1 1
Gentamicin EIA µg/mL

Mean 1.94 1.99 5.37 5.33 8.83 9.09
SD
CV
1 0.072
3.7
0.091
4.5
2 0.084
1.6
0.242
4.5
3 0.481
5.4
0.537
5.9
# Points 111 4000 29 1733 82 2875
# Labs 4 5 1 3 3 5

Mean 1.94 1.96 5.37 5.35 9.07 9.10
SD
CV
1 0.074
3.8
0.128
6.5
2 0.084
1.6
0.312
5.8
3 0.638
7.0
0.692
7.6
# Points 142 5962 29 2023 114 4743
# Labs 5 14 1 5 4 14
Gentamicin Immunoturbidimetric µg/mL

Mean −− 1.99 −− 5.16 −− 8.52
SD
CV
1 −−
−−
0.168
8.5
2 −−
−−
0.144
2.8
3 −−
−−
0.400
4.7
# Points −− 554 −− 321 −− 312
# Labs 3 2 1

Mean −− 1.91 −− 5.38 −− 9.18
SD
CV
1 −−
−−
0.152
8.0
2 −−
−−
0.349
6.5
3 −−
−−
0.650
7.1
# Points −− 635 −− 602 −− 570
# Labs 1 1 1

Mean −− 2.28 −− 6.54 −− 10.41
SD
CV
1 −−
−−
0.183
8.0
2 −−
−−
0.340
5.2
3 −−
−−
0.358
3.4
# Points −− 1430 −− 161 −− 1416
# Labs 10 4 10

Mean 1.89 1.98 4.91 5.04 8.05 8.17
SD
CV
1 0.145
7.7
0.171
8.6
2 0.143
2.9
0.205
4.1
3 0.303
3.8
0.406
5.0
# Points 140 2720 31 693 141 2680
# Labs 3 4 1 1 3 4
Roche cobas 6000/8000/c 311 • Thermo Scientific Clinical Chemistry

Mean −− 1.78 −− 4.97 −− 8.43
SD
CV
1 −−
−−
0.179
10.0
2−−
−−
0.262
5.3
3 −−
−−
0.356
4.2
# Points −− 389 −− 387 −− 392
# Labs 2 2 2

Mean −− 1.80 −− 4.88 −− 7.76
SD
CV
1 −−
−−
0.125
6.9
2 −−
−−
0.227
4.6
3 −−
−−
0.311
4.0
# Points −− 1155 −− 1172 −− 1193
# Labs 2 2 2

Mean −− 1.99 −− 5.12 −− 8.46
SD
CV
1 −−
−−
0.192
9.6
2 −−
−−
0.225
4.4
3 −−
−−
0.633
7.5
# Points −− 11 −− 8 −− 7
# Labs 1 1 1

Mean −− 1.79 −− 5.18 −− 9.07
SD
CV
1 −−
−−
0.148
8.3
2 −−
−−
0.240
4.6
3 −−
−−
0.302
3.3
# Points −− 2906 −− 1335 −− 2835
# Labs 8 4 6
Gentamicin Immunoturbidimetric µg/mL

Mean 1.74 1.81 −− −− 8.65 9.13
SD
CV
1 0.079
4.6
0.124
6.9
2 −−
−−
−−
−−
3 0.299
3.5
0.320
3.5
# Points 88 4980 −− −− 88 5232
# Labs 3 15 3 15

Mean 1.76 1.78 5.27 5.24 8.97 8.95
SD
CV
1 0.131
7.4
0.136
7.6
2 0.186
3.5
0.218
4.2
3 0.337
3.8
0.327
3.7
# Points 81 28535 12 7572 84 27407
# Labs 6 77 2 19 6 77

Mean 1.81 1.82 5.01 5.20 8.47 8.94
SD
CV
1 0.145
8.0
0.173
9.5
2 0.225
4.5
0.304
5.8
3 0.501
5.9
0.524
5.9
# Points 309 43315 43 12251 313 42044
# Labs 12 123 3 36 12 119
Gentamicin KIMS (Roche) µg/mL

Mean −− 1.87 −− −− −− 8.28
SD
CV
1 −−
−−
0.199
10.6
2 −−
−−
−−
−−
3 −−
−−
0.392
4.7
# Points −− 220 −− −− −− 225
# Labs 1 1
Roche cobas c 303/503 • Roche GENT2, REF 08057770

Mean −− 1.73 −− −− −− 7.62
SD
CV
1 −−
−−
0.131
7.6
2 −−
−−
−−
−−
3 −−
−−
0.315
4.1
# Points −− 964 −− −− −− 970
# Labs 3 3

Mean −− 1.75 −− −− −− 7.75
SD
CV
1 −−
−−
0.156
8.9
2 −−
−−
−−
−−
3 −−
−−
0.418
5.4
# Points −− 1184 −− −− −− 1195
# Labs 4 4
GGT (Gamma Glutamyltransferase) G−glutamyl−carboxy−nitroanilide U/L @ 22° C

Mean −− 26.25 −− 81.10 −− −−
SD
CV
1 −−
−−
1.12
4.3
2 −−
−−
1.35
1.7
3 −−
−−
−−
−−
# Points −− 126 −− 126 −− −−
# Labs 1 1

Mean −− 26.69 −− −− −− 128.3
SD
CV
1 −−
−−
0.876
3.3
2 −−
−−
−−
−−
3 −−
−−
2.10
1.6
# Points −− 406 −− −− −− 402
# Labs 2 2
Method Group • G−glutamyl−carboxy−nitroanilide

Mean −− 26.59 −− 81.10 −− 128.3
SD
CV
1 −−
−−
0.958
3.6
2 −−
−−
1.35
1.7
3 −−
−−
2.10
1.6
# Points −− 532 −− 126 −− 402
# Labs 3 1 2

Mean −− 25.82 −− −− −− 127.6
SD
CV
1 −−
−−
0.738
2.9
2 −−
−−
−−
−−
3 −−
−−
2.89
2.3
# Points −− 106 −− −− −− 106
# Labs 1 1

Mean −− 22.18 −− 63.52 −− 103.3
SD
CV
1 −−
−−
1.82
8.2
2 −−
−−
1.35
2.1
3 −−
−−
3.47
3.4
# Points −− 342 −− 97 −− 342
# Labs 3 1 3
ILab Series
Mean 20.82 21.10 63.09 63.33 −− −−
SD
CV
1 1.17
5.6
1.56
7.4
2 2.88
4.6
2.05
3.2
3 −−
−−
−−
−−
# Points 11 48 11 48 −− −−
# Labs 1 1 1 1

Mean 27.54 27.35 82.54 82.12 −− −−
SD
CV
1 0.576
2.1
0.617
2.3
2 1.88
2.3
1.48
1.8
3 −−
−−
−−
−−
# Points 28 68 28 68 −− −−
# Labs 1 1 1 1

Mean −− 22.49 −− −− −− 109.0
SD
CV
1 −−
−−
0.994
4.4
2 −−
−−
−−
−−
3 −−
−−
2.77
2.5
# Points −− 528 −− −− −− 509
# Labs 1 1
Roche cobas c 303/503 • Roche GGT−2, REF 08057796 (Szasz)

Mean 23.21 22.77 −− −− 110.2 110.0
SD
CV
1 0.479
2.1
0.976
4.3
2
−−
−−
−−
−−
3 0.955
0.9
2.79
2.5
# Points 34 846 −− −− 34 821
# Labs 1 1 1 1

Mean −− 27.12 −− 76.90 −− 121.3
SD
CV
1 −−
−−
2.20
8.1
2 −−
−−
3.41
4.4
3 −−
−−
4.01
3.3
# Points −− 281 −− 499 −− 503
# Labs 2 2 1

Mean −− 35.68 −− −− −− 150.5
SD
CV
1 −−
−−
1.05
3.0
2 −−
−−
−−
−−
3 −−
−−
2.28
1.5
# Points −− 183 −− −− −− 183
# Labs 1 1

Mean 24.51 24.87 77.05 74.66 110.2 116.5
SD
CV
1 2.62
10.7
4.25
17.1
2 9.12
11.8
6.58
8.8
3 0.955
0.9
13.40
11.5
# Points 73 1874 39 712 34 1955
# Labs 3 10 2 5 1 7

Mean 26.11 25.81 79.15 78.63 128.9 126.9
SD
CV
1 1.80
6.9
1.39
5.4
2 5.17
6.5
3.80
4.8
3 6.21
4.8
5.60
4.4
# Points 825 34339 525 21002 418 32640
# Labs 34 122 26 86 20 98

Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH GGT REF 7D65
Mean 26.44 26.55 81.66 82.33 −− −−
SD
CV
1 1.52
5.7
1.42
5.4
2
4.97
6.1
4.44
5.4
3 −−
−−
−−
−−
# Points 44 147 44 148 −− −−
# Labs 2 2 2 2
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH GGT2, REF 04T00 (Factored, IFCC Correlated)
Mean −− 27.49 −− −− −− 133.2
SD
CV
1 −−
−−
0.985
3.6
2
−−
−−
−−
−−
3 −−
−−
3.39
2.5
# Points −− 146 −− −− −− 141
# Labs 2 2
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c GGT, REF 07P73

Mean −− 24.24 −− 74.49 −− −−
SD
CV
1 −−
−−
0.515
2.1
2 −−
−−
0.573
0.8
3 −−
−−
−−
−−
# Points −− 34 −− 33 −− −−
# Labs 1 1
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c GGT, REF 07P73 (Factored, IFCC Correlated)
Mean 27.40 26.00 83.13 79.08 −− −−
SD
CV
1 0.563
2.1
1.70
6.5
2 1.70
2.0
4.77
6.0
3 −−
−−
−−
−−
# Points 30 78 30 78 −− −−
# Labs 1 2 1 2
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c GGT2 REF 04T96

Mean 27.62 27.45 83.68 82.95 −− −−
SD
CV
1 1.01
3.7
1.45
5.3
2 3.30
3.9
3.82
4.6
3 −−
−−
−−
−−
# Points 98 397 98 402 −− −−
# Labs 4 5 4 5
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c GGT2, REF 04T96 (Factored, IFCC Correlated)
Mean 27.55 27.91 82.98 83.71 132.4 134.9
SD
CV
1 0.653
2.4
0.868
3.1
2 1.66
2.0
2.49
3.0
3 0.650
0.5
2.80
2.1
# Points 58 722 45 275 13 425
# Labs 2 4 2 2 1 2

Mean 27.11 27.39 80.49 81.72 127.6 129.9
SD
CV
1 0.280
1.0
0.501
1.8
2 0.570
0.7
1.03
1.3
3 0.990
0.8
2.15
1.7
# Points 16 400 16 448 16 455
# Labs 1 1 1 1 1 1

Mean −− −− −− 78.04 −− 124.8
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.12
1.4
3 −−
−−
1.90
1.5
# Points −− −− −− 580 −− 555
# Labs 2 2

Mean 21.99 22.03 65.52 65.19 105.3 104.6
SD
CV
1 1.04
4.7
1.12
5.1
2 2.73
4.2
2.44
3.7
3 3.17
3.0
4.71
4.5
# Points 1274 36100 1096 19353 264 30606
# Labs 45 130 38 80 11 90

Mean 23.91 23.73 70.96 70.41 −− −−
SD
CV
1 0.450
1.9
0.350
1.5
2 1.12
1.6
0.828
1.2
3 −−
−−
−−
−−
# Points 25 268 25 198 −− −−
# Labs 1 1 1 1

Mean −− 27.12 80.39 80.70 128.7 128.7
SD
CV
1 −−
−−
0.820
3.0
2 1.03
1.3
1.54
1.9
3 1.53
1.2
2.44
1.9
# Points −− 2331 87 5329 88 7096
# Labs 5 2 15 2 17

Mean −− 24.28 −− −− −− 115.8
SD
CV
1 −−
−−
0.612
2.5
2 −−
−−
−−
−−
3 −−
−−
2.53
2.2
# Points −− 215 −− −− −− 194
# Labs 1 1

Mean −− 25.90 −− 76.33 −− 121.4
SD
CV
1 −−
−−
0.600
2.3
2 −−
−−
1.79
2.3
3 −−
−−
2.63
2.2
# Points −− 212 −− 212 −− 211
# Labs 1 1 1

Mean 23.31 23.15 72.53 72.12 116.7 116.1
SD
CV
1 0.771
3.3
0.854
3.7
2 1.39
1.9
1.73
2.4
3 1.62
1.4
2.46
2.1
# Points 62 629 62 695 62 698
# Labs 2 2 2 2 2 2

Mean −− 26.94 −− 80.39 −− 127.2
SD
CV
1 −−
−−
0.347
1.3
2 −−
−−
1.20
1.5
3 −−
−−
1.77
1.4
# Points −− 2058 −− 2348 −− 2334
# Labs 2 3 3

Mean −− 23.99 −− −− −− 121.8
SD
CV
1 −−
−−
1.37
5.7
2 −−
−−
−−
−−
3 −−
−−
2.21
1.8
# Points −− 310 −− −− −− 306
# Labs 1 1

Mean −− −− 79.16 78.84 126.5 125.3
SD
CV
1 −−
−−
−−
−−
2 0.897
1.1
4.03
5.1
3 1.43
1.1
3.68
2.9
# Points −− −− 13 108 10 63
# Labs 2 2 2 2
ERBA XL−640
Mean −− 28.30 −− 83.99 −− −−
SD
CV
1 −−
−−
0.732
2.6
2 −−
−−
1.46
1.7
3 −−
−−
−−
−−
# Points −− 46 −− 46 −− −−
# Labs 1 1

Mean −− 33.43 −− 99.71 −− −−
SD
CV
1 −−
−−
0.930
2.8
2 −−
−−
2.04
2.0
3 −−
−−
−−
−−
# Points −− 53 −− 51 −− −−
# Labs 1 1

Mean −− 26.97 −− 79.19 −− 128.2
SD
CV
1 −−
−−
0.810
3.0
2 −−
−−
1.86
2.4
3 −−
−−
3.92
3.1
# Points −− 3029 −− 1321 −− 3039
# Labs 10 4 10

Mean −− −− −− 71.74 −− 112.4
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.38
3.3
3 −−
−−
3.59
3.2
# Points −− −− −− 108 −− 107
# Labs 1 1

Mean −− 26.90 −− −− −− −−
SD
CV
1 −−
−−
1.03
3.8
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 70 −− −− −− −−
# Labs 1

Mean −− 26.83 −− −− −− 129.4
SD
CV
1 −−
−−
1.05
3.9
2 −−
−−
−−
−−
3 −−
−−
2.39
1.8
# Points −− 89 −− −− −− 90
# Labs 1 1

Mean −− 26.40 −− −− −− 119.9
SD
CV
1 −−
−−
2.07
7.8
2 −−
−−
−−
−−
3 −−
−−
4.28
3.6
# Points −− 10 −− −− −− 10
# Labs 1 1
Mindray BS Series
Mean 26.16 27.73 78.62 80.84 124.3 126.9
SD
CV
1 0.680
2.6
1.80
6.5
2 0.900
1.1
1.36
1.7
3 1.58
1.3
1.94
1.5
# Points 21 242 21 416 21 423
# Labs 1 2 1 2 1 2

Mean −− −− −− 78.64 −− 125.4
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.04
1.3
3 −−
−−
1.42
1.1
# Points −− −− −− 284 −− 284
# Labs 2 2
RANDOX RX daytona
Mean 27.55 26.38 −− 70.86 −− −−
SD
CV
1 3.10
11.3
2.43
9.2
2 −−
−−
3.32
4.7
3 −−
−−
−−
−−
# Points 20 201 −− 132 −− −−
# Labs 1 1 1
RANDOX RX imola
Mean 27.43 26.58 81.03 78.98 −− −−
SD
CV
1 0.591
2.2
1.60
6.0
2 0.946
1.2
3.27
4.1
3 −−
−−
−−
−−
# Points 26 226 24 195 −− −−
# Labs 1 1 1 1

Mean 23.45 23.53 72.96 70.13 111.2 111.4
SD
CV
1 0.749
3.2
0.961
4.1
2 3.72
5.1
3.00
4.3
3 2.44
2.2
3.60
3.2
# Points 277 18749 199 8614 249 17886
# Labs 9 60 5 27 8 57

Mean −− 23.08 −− 70.31 −− 111.9
SD
CV
1 −−
−−
0.771
3.3
2 −−
−−
1.74
2.5
3 −−
−−
2.77
2.5
# Points −− 1574 −− 1458 −− 1582
# Labs 6 4 6

Mean −− 22.48 −− −− −− 109.5
SD
CV
1 −−
−−
1.32
5.9
2
−−
−−
−−
−−
3 −−
−−
4.37
4.0
# Points −− 1598 −− −− −− 1491
# Labs 8 8

Mean 25.36 25.88 76.93 78.96 125.3 127.5
SD
CV
1 1.46
5.8
1.42
5.5
2 4.05
5.3
4.02
5.1
3 5.83
4.7
5.54
4.3
# Points 103 601 107 584 78 499
# Labs 3 3 3 3 2 3

Mean −− 22.59 −− −− −− 113.3
SD
CV
1 −−
−−
0.507
2.2
2 −−
−−
−−
−−
3 −−
−−
2.02
1.8
# Points −− 17 −− −− −− 16
# Labs 1 1

Mean 25.52 26.51 75.29 80.00 118.5 128.0
SD
CV
1 0.570
2.2
1.47
5.5
2 1.24
1.6
3.60
4.5
3 0.930
0.8
4.95
3.9
# Points 31 821 31 719 31 615
# Labs 1 3 1 3 1 3

Mean −− 24.07 −− 74.59 −− 119.2
SD
CV
1 −−
−−
0.926
3.8
2 −−
−−
1.78
2.4
3 −−
−−
2.76
2.3
# Points −− 557 −− 557 −− 558
# Labs 2 2 2
Mean −− −− −− 76.33 −− 121.1
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.30
3.0
3 −−
−−
4.02
3.3
# Points −− −− −− 358 −− 355
# Labs 1 1

Mean −− 26.76 −− −− −− 128.3
SD
CV
1 −−
−−
0.769
2.9
2 −−
−−
−−
−−
3 −−
−−
1.52
1.2
# Points −− 278 −− −− −− 277
# Labs 1 1

Mean 23.32 25.94 73.03 72.75 122.2 125.6
SD
CV
1 1.36
5.8
2.61
10.0
2 6.71
9.2
5.25
7.2
3 1.99
1.6
4.75
3.8
# Points 22 4818 77 1874 22 4947
# Labs 1 14 3 9 1 13

Mean 27.18 26.98 78.88 77.70 128.7 122.6
SD
CV
1 1.90
7.0
2.49
9.2
2 2.56
3.2
4.18
5.4
3 3.60
2.8
4.05
3.3
# Points 394 16347 400 11906 68 12788
# Labs 9 62 11 48 4 50
Siemens Atellica CH Analyzer • Reagent, Alternate Calibration − Shift UP

Mean 30.19 28.39 −− −− 134.0 125.8
SD
CV
1 1.40
4.6
2.57
9.0
2 −−
−−
−−
−−
3 3.15
2.4
5.81
4.6
# Points 32 664 −− −− 33 758
# Labs 1 2 1 2

Mean 36.06 37.14 99.00 97.86 149.5 152.7
SD
CV
1 1.67
4.6
2.52
6.8
2 2.14
2.2
3.35
3.4
3 4.68
3.1
4.39
2.9
# Points 191 21947 77 2573 130 19606
# Labs 7 57 4 14 5 49

Mean −− 34.56 −− 93.77 −− 149.0
SD
CV
1 −−
−−
1.04
3.0
2 −−
−−
1.74
1.9
3 −−
−−
1.80
1.2
# Points −− 171 −− 69 −− 14
# Labs 2 1 1

Mean 32.74 33.11 97.04 97.03 154.5 154.5
SD
CV
1 1.98
6.0
2.14
6.5
2 2.05
2.1
2.75
2.8
3 2.97
1.9
3.02
2.0
# Points 1870 148K 602 36368 1843 137K
# Labs 55 313 18 75 53 294
Siemens Dimension Vista • Factored, IFCC Correlated

Mean −− 36.93 −− 90.86 −− 139.4
SD
CV
1 −−
−−
1.80
4.9
2 −−
−−
1.96
2.2
3 −−
−−
2.35
1.7
# Points −− 375 −− 348 −− 349
# Labs 2 2 2

Mean −− 26.01 −− 78.68 −− 125.7
SD
CV
1 −−
−−
0.774
3.0
2 −−
−−
1.68
2.1
3 −−
−−
2.61
2.1
# Points −− 460 −− 465 −− 486
# Labs 3 3 3

Mean 34.88 35.19 −− −− 165.0 165.1
SD
CV
1 0.460
1.3
1.21
3.4
2 −−
−−
−−
−−
3 2.82
1.7
3.61
2.2
# Points 5 28 −− −− 5 24
# Labs 1 1 1 1

Mean −− 36.82 −− −− −− 163.3
SD
CV
1 −−
−−
2.15
5.8
2 −−
−−
−−
−−
3 −−
−−
8.90
5.5
# Points −− 133 −− −− −− 82
# Labs 3 1

Mean 27.75 29.75 77.92 81.81 140.2 138.5
SD
CV
1 4.84
17.4
5.15
17.3
2 11.57
14.8
12.21
14.9
3 18.32
13.1
19.43
14.0
# Points 5424 300K 3579 120K 3351 279K
# Labs 182 845 128 412 116 737

Toshiba−TBA
Mean 28.50 27.64 −− −− 133.0 129.2
SD
CV
1 0.710
2.5
0.595
2.2
2 −−
−−
−−
−−
3 0.000
0.0
1.55
1.2
# Points 2 362 −− −− 1 361
# Labs 1 1 1 1

Mean 28.50 27.64 −− −− 133.0 129.2
SD
CV
1 0.710
2.5
0.595
2.2
2 −−
−−
−−
−−
3 0.000
0.0
1.55
1.2
# Points 2 362 −− −− 1 361
# Labs 1 1 1 1
GGT (Gamma Glutamyltransferase) G−glutamyl−carboxy−nitroanilide U/L

Mean −− 27.00 −− 132.0 −− −−
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
0.000
0.0
3 −−
−−
−−
−−
# Points −− 1 −− 1 −− −−
# Labs 1 1

Mean −− 27.00 −− 132.0 −− −−
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
0.000
0.0
3 −−
−−
−−
−−
# Points −− 1 −− 1 −− −−
# Labs 1 1
GGT (Gamma Glutamyltransferase) G−glutamyl−carboxy−nitroanilide − IFCC Ref. Proc., Calibrated U/L @ 25° C
Mean −− 26.11 −− −− −− 131.9
SD
CV
1 −−
−−
1.36
5.2
2 −−
−−
−−
−−
3 −−
−−
5.20
3.9
# Points −− 116 −− −− −− 118
# Labs 1 1

Mean −− 20.74 −− 66.73 −− 103.5
SD
CV
1 −−
−−
0.446
2.2
2 −−
−−
0.594
0.9
3 −−
−−
1.46
1.4
# Points −− 38 −− 15 −− 15
# Labs 1 1 1
Method Group • G−glutamyl−carboxy−nitroanilide − IFCC Ref. Proc., Calibrated

Mean −− 24.78 −− 66.73 −− 128.7
SD
CV
1 −−
−−
2.61
10.5
2
−−
−−
0.594
0.9
3 −−
−−
10.27
8.0
# Points −− 154 −− 15 −− 133
# Labs 2 1 2
Mean 24.10 24.48 73.72 74.84 118.2 120.1
SD
CV
1 0.707
2.9
1.07
4.4
2 1.74
2.4
2.40
3.2
3 1.98
1.7
3.55
3.0
# Points 196 7636 196 6906 137 8287
# Labs 5 24 5 22 3 19
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH GGT2, REF 04T00 (Factored, IFCC Correlated)
Mean −− 27.06 −− 83.63 −− −−
SD
CV
1 −−
−−
0.725
2.7
2−−
−−
2.57
3.1
3 −−
−−
−−
−−
# Points −− 35 −− 30 −− −−
# Labs 1 1
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c GGT, REF 07P73

Mean −− 27.99 −− −− −− 136.1
SD
CV
1 −−
−−
2.28
8.2
2 −−
−−
−−
−−
3 −−
−−
10.26
7.5
# Points −− 225 −− −− −− 220
# Labs 1 1
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c GGT, REF 07P73 (Factored, IFCC Correlated)
Mean −− 23.40 −− 71.57 −− −−
SD
CV
1 −−
−−
0.459
2.0
2 −−
−−
1.17
1.6
3 −−
−−
−−
−−
# Points −− 22 −− 22 −− −−
# Labs 1 1
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c GGT2, REF 04T96 (Factored, IFCC Correlated)
Mean 27.83 28.02 84.61 84.79 136.9 135.4
SD
CV
1 0.904
3.2
0.905
3.2
2 2.28
2.7
2.08
2.5
3 3.39
2.5
3.08
2.3
# Points 142 1509 144 1473 90 1448
# Labs 7 11 7 11 5 8

Mean 25.96 26.02 78.35 80.38 127.7 128.1
SD
CV
1 1.48
5.7
1.40
5.4
24.04
5.2
4.09
5.1
3 4.90
3.8
6.23
4.9
# Points 237 4887 306 4367 196 3870
# Labs 8 17 9 13 5 8

Mean −− 26.76 −− 80.71 −− 127.8
SD
CV
1 −−
−−
0.668
2.5
2 −−
−−
1.36
1.7
3 −−
−−
1.73
1.4
# Points −− 265 −− 265 −− 265
# Labs 1 1 1

Mean 25.12 25.57 75.21 78.66 120.2 121.5
SD
CV
1 0.996
4.0
1.84
7.2
2 3.45
4.6
3.28
4.2
3 5.44
4.5
8.13
6.7
# Points 202 14357 235 12593 232 17166
# Labs 4 37 7 32 7 46

Mean 26.89 26.86 81.91 80.80 129.5 128.9
SD
CV
1 0.880
3.3
0.956
3.6
2 3.04
3.7
2.41
3.0
3 4.89
3.8
4.26
3.3
# Points 82 32178 82 34971 146 34988
# Labs 5 89 2 90 5 96

Mean −− −− −− 78.77 −− 124.8
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.898
1.1
3 −−
−−
0.972
0.8
# Points −− −− −− 165 −− 165
# Labs 1 1

Mean 28.74 31.78 72.67 73.04 128.0 123.6
SD
CV
1 2.38
8.3
6.37
20.0
2 4.43
6.1
4.50
6.2
3 3.94
3.1
3.82
3.1
# Points 54 674 40 531 5 44
# Labs 3 4 3 4 1 2

Mean −− 32.27 −− −− −− −−
SD
CV
1 −−
−−
0.868
2.7
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 30 −− −− −− −−
# Labs 1

Mean −− 26.02 −− 79.15 −− 126.4
SD
CV
1 −−
−−
0.921
3.5
2 −−
−−
2.02
2.5
3 −−
−−
3.19
2.5
# Points −− 1549 −− 1568 −− 1548
# Labs 3 3 3
Mindray BS Series
Mean −− 27.22 −− 127.1 −− −−
SD
CV
1 −−
−−
0.345
1.3
2 −−
−−
0.682
0.5
3 −−
−−
−−
−−
# Points −− 221 −− 220 −− −−
# Labs 1 1
Mean −− −− −− 77.03 −− 122.0
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.907
1.2
3 −−
−−
1.07
0.9
# Points −− −− −− 148 −− 148
# Labs 1 1
Mindray CL Series
Mean −− −− −− 83.23 −− 131.0
SD
CV
1 −−
−−
−−
−−
2 −−
−−
3.69
4.4
3 −−
−−
5.90
4.5
# Points −− −− −− 87 −− 89
# Labs 1 1

Mean 26.07 26.65 81.00 80.44 125.4 126.9
SD
CV
1 1.03
3.9
1.10
4.1
2 1.05
1.3
2.66
3.3
3 2.75
2.2
3.60
2.8
# Points 894 34822 30 22354 825 39243
# Labs 16 81 1 73 14 92

Mean 26.71 26.64 82.48 81.34 130.4 129.6
SD
CV
1 0.756
2.8
0.930
3.5
2 2.32
2.8
2.02
2.5
3 2.50
1.9
2.89
2.2
# Points 107 2322 99 2356 99 2099
# Labs 4 6 3 4 4 5
Roche cobas c 303/503 • Roche GGT−2, REF 08057796 (IFCC)

Mean 26.46 26.35 81.24 81.38 128.4 128.8
SD
CV
1 0.974
3.7
0.976
3.7
0.9552
1.2
1.32
1.6
3 2.09
1.6
2.40
1.9
# Points 141 4699 52 2621 115 4762
# Labs 5 16 2 4 4 9

Mean −− 22.41 −− −− −− 110.5
SD
CV
1 −−
−−
0.685
3.1
2
−−
−−
−−
−−
3 −−
−−
2.76
2.5
# Points −− 135 −− −− −− 137
# Labs 2 2
Roche cobas c 303/503 • Roche PHOS2, REF 08058610

Mean 26.09 26.18 −− −− −− −−
SD
CV
1 0.509
2.0
0.595
2.3
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points 55 95 −− −− −− −−
# Labs 1 1

Mean 26.52 26.37 79.77 79.26 127.1 124.6
SD
CV
1 0.692
2.6
0.889
3.4
2 1.23
1.5
2.00
2.5
3 1.70
1.3
3.88
3.1
# Points 129 1458 131 1641 14 635
# Labs 2 3 2 3 1 3

Mean −− 22.69 −− 71.02 −− 114.0
SD
CV
1 −−
−−
0.465
2.0
2 −−
−−
1.000
1.4
3 −−
−−
1.64
1.4
# Points −− 65 −− 65 −− 65
# Labs 1 1 1

Mean −− 26.03 −− 77.95 −− −−
SD
CV
1 −−
−−
0.769
3.0
2 −−
−−
1.68
2.2
3 −−
−−
−−
−−
# Points −− 101 −− 95 −− −−
# Labs 1 1
Mean −− −− −− 81.29 −− 129.0
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.06
1.3
3 −−
−−
2.43
1.9
# Points −− −− −− 269 −− 292
# Labs 1 1
Mean −− 27.79 −− 80.99 −− 128.7
SD
CV
1 −−
−−
0.642
2.3
2 −−
−−
2.61
3.2
3 −−
−−
3.30
2.6
# Points −− 271 −− 270 −− 229
# Labs 1 1 1

Mean −− −− −− 81.80 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.66
2.0
3 −−
−−
−−
−−
# Points −− −− −− 25 −− −−
# Labs 1

Mean −− 25.88 −− 77.74 −− 125.6
SD
CV
1 −−
−−
2.73
10.6
2 −−
−−
3.23
4.2
3 −−
−−
3.65
2.9
# Points −− 8283 −− 8566 −− 7996
# Labs 24 22 20

Mean 24.58 27.26 78.35 78.11 127.4 123.3
SD
CV
1 1.92
7.8
2.21
8.1
2 2.04
2.6
3.02
3.9
3 2.91
2.3
3.49
2.8
# Points 26 4492 26 3573 26 3855
# Labs 1 15 1 11 1 13

Mean 33.43 31.72 85.38 84.13 133.2 132.9
SD
CV
1 2.69
8.1
2.18
6.9
2 1.27
1.5
3.05
3.6
3 1.69
1.3
2.87
2.2
# Points 79 6144 54 2506 56 4519
# Labs 3 20 2 13 2 10

Mean 30.53 31.11 −− 83.52 132.1 131.5
SD
CV
1 1.16
3.8
1.62
5.2
2 −−
−−
2.83
3.4
3 5.65
4.3
3.61
2.7
# Points 225 13087 −− 3978 223 10382
# Labs 4 29 15 4 21

Mean 34.42 33.30 95.03 96.15 147.1 154.9
SD
CV
1 2.45
7.1
2.42
7.3
2 3.99
4.2
3.14
3.3
3 3.26
2.2
3.86
2.5
# Points 483 20109 334 15374 59 4981
# Labs 14 28 12 18 2 13

Mean −− −− 87.30 87.09 −− −−
SD
CV
1 −−
−−
−−
−−
2 1.66
1.9
2.63
3.0
3 −−
−−
−−
−−
# Points −− −− 19 27 −− −−
# Labs 1 1
Toshiba−TBA
Mean −− −− −− −− −− 121.8
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
2.61
2.1
# Points −− −− −− −− −− 80
# Labs 1
Method Group • G−glutamyl−carboxy−nitroanilide − IFCC Ref. Proc., Calibrated
Mean 28.58 28.71 82.19 82.67 127.9 129.0
SD
CV
1 4.11
14.4
3.86
13.5
2
8.04
9.8
6.77
8.2
3 7.00
5.5
8.06
6.2
# Points 3368 180K 1780 138K 2359 164K
# Labs 89 458 58 370 62 412
GGT (Gamma Glutamyltransferase) G−glutamyl−carboxy−nitroanilide−Samsung U/L @ 37° C

Roche cobas c 303/503 • Roche GGT−2, REF 08057796 (IFCC)
Mean 26.40 26.32 −− −− −− −−
SD
CV
1 0.562
2.1
0.554
2.1
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points 57 80 −− −− −− −−
# Labs 1 1
Method Group • G−glutamyl−carboxy−nitroanilide−Samsung

Mean 26.40 26.32 −− −− −− −−
SD
CV
1 0.562
2.1
0.554
2.1
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points 57 80 −− −− −− −−
# Labs 1 1
GGT (Gamma Glutamyltransferase) G−glutamyl−p−nitroanilide U/L @ 25° C

Mean −− 23.15 −− −− −− 119.4
SD
CV
1 −−
−−
1.57
6.8
2 −−
−−
−−
−−
3 −−
−−
1.70
1.4
# Points −− 20 −− −− −− 20
# Labs 1 1
Method Group • G−glutamyl−p−nitroanilide

Mean −− 23.15 −− −− −− 119.4
SD
CV
1 −−
−−
1.57
6.8
2 −−
−−
−−
−−
3 −−
−−
1.70
1.4
# Points −− 20 −− −− −− 20
# Labs 1 1

Mean −− 20.80 −− 62.84 −− 100.1
SD
CV
1 −−
−−
0.577
2.8
2 −−
−−
1.19
1.9
3 −−
−−
1.81
1.8
# Points −− 730 −− 699 −− 742
# Labs 2 2 2

Mean −− −− −− 77.96 −− 123.8
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.00
1.3
3 −−
−−
1.68
1.4
# Points −− −− −− 340 −− 340
# Labs 1 1

Mean −− 25.02 −− 76.58 −− 122.9
SD
CV
1 −−
−−
1.17
4.7
2 −−
−−
2.09
2.7
3 −−
−−
2.84
2.3
# Points −− 3081 −− 602 −− 2319
# Labs 13 3 11

Mean −− −− 76.75 76.19 120.7 120.3
SD
CV
1 −−
−−
−−
−−
2 1.05
1.4
1.23
1.6
3 1.55
1.3
1.98
1.6
# Points −− −− 32 134 32 135
# Labs 1 1 1 1

Mean 36.17 32.77 −− 100.6 −− 155.7
SD
CV
1 0.753
2.1
1.33
4.0
2 −−
−−
3.35
3.3
3 −−
−−
4.01
2.6
# Points 6 503 −− 448 −− 342
# Labs 1 4 4 2
Fuji Dri−Chem Series • Fuji Dri−Chem GGT−PIII, REF 9903120

Mean −− 29.18 −− 96.40 −− −−
SD
CV
1 −−
−−
1.03
3.5
2 −−
−−
2.81
2.9
3 −−
−−
−−
−−
# Points −− 34 −− 35 −− −−
# Labs 2 3

Mean −− 23.98 −− 72.24 −− 114.6
SD
CV
1 −−
−−
0.866
3.6
2 −−
−−
1.29
1.8
3 −−
−−
1.83
1.6
# Points −− 664 −− 688 −− 689
# Labs 2 2 2

Mean −− 35.80 −− 117.5 −− 163.2
SD
CV
1 −−
−−
0.283
0.8
2 −−
−−
0.071
0.1
3 −−
−−
0.919
0.6
# Points −− 2 −− 2 −− 2
# Labs 1 1 1

Mean −− 37.50 −− 121.5 −− 171.1
SD
CV
1 −−
−−
1.13
3.0
2 −−
−−
1.77
1.5
3 −−
−−
0.070
0.0
# Points −− 2 −− 2 −− 2
# Labs 1 1 1

Mean 36.91 36.87 119.1 118.7 168.2 167.9
SD
CV
1 0.513
1.4
0.511
1.4
2 1.20
1.0
1.60
1.3
3 1.18
0.7
1.64
1.0
# Points 31 34 32 36 31 34
# Labs 2 3 2 3 2 3
Method Group • G−glutamyl−p−nitroanilide

Mean 36.79 26.67 97.94 76.92 144.1 127.7
SD
CV
1 0.612
1.7
4.54
17.0
2 21.38
21.8
12.95
16.8
3 23.97
16.6
18.86
14.8
# Points 37 6108 64 2989 63 5711
# Labs 3 30 3 21 3 26
GGT (Gamma Glutamyltransferase) G−glutamyl−p−nitroanilide−VITROS U/L @ 37° C

Mean −− 36.14 113.3 119.8 −− 160.3
SD
CV
1 −−
−−
2.07
5.7
2 0.580
0.5
5.05
4.2
3 −−
−−
4.31
2.7
# Points −− 1097 3 980 −− 947
# Labs 11 1 10 7

Mean −− 37.55 −− 114.1 −− 159.6
SD
CV
1 −−
−−
1.18
3.1
2 −−
−−
2.02
1.8
3 −−
−−
2.17
1.4
# Points −− 529 −− 4 −− 25
# Labs 4 1 2

Mean −− 37.13 −− 119.7 −− 165.7
SD
CV
1 −−
−−
1.47
4.0
2 −−
−−
2.99
2.5
3 −−
−−
3.76
2.3
# Points −− 2899 −− 801 −− 2805
# Labs 25 11 25

Mean −− 36.63 −− 118.0 −− 164.4
SD
CV
1 −−
−−
1.52
4.1
2 −−
−−
1.46
1.2
3 −−
−−
3.57
2.2
# Points −− 784 −− 139 −− 751
# Labs 7 2 7

Mean −− 36.64 −− 118.1 −− 165.2
SD
CV
1 −−
−−
1.26
3.4
2 −−
−−
2.44
2.1
3 −−
−−
3.68
2.2
# Points −− 3105 −− 1502 −− 2811
# Labs 23 11 22

Mean −− 37.72 −− 119.0 −− 164.8
SD
CV
1 −−
−−
1.21
3.2
2 −−
−−
2.48
2.1
3 −−
−−
4.07
2.5
# Points −− 692 −− 430 −− 725
# Labs 12 8 12

Mean −− 38.25 −− 120.0 −− 168.1
SD
CV
1 −−
−−
0.947
2.5
2 −−
−−
0.881
0.7
3 −−
−−
4.03
2.4
# Points −− 643 −− 60 −− 550
# Labs 6 1 3

Mean 36.63 36.81 121.4 120.3 166.6 167.8
SD
CV
1 1.46
4.0
1.19
3.2
2 1.89
1.6
2.64
2.2
3 5.52
3.3
4.71
2.8
# Points 127 3720 63 1904 125 3463
# Labs 6 37 3 23 6 32

Mean 34.72 36.26 116.0 118.5 161.1 166.1
SD
CV
1 1.15
3.3
1.32
3.7
2 2.05
1.8
2.67
2.3
3 2.63
1.6
4.07
2.5
# Points 253 6182 115 2340 125 5669
# Labs 9 37 5 15 4 28

Mean −− 36.74 −− 116.5 −− 167.9
SD
CV
1 −−
−−
0.934
2.5
2 −−
−−
1.05
0.9
3 −−
−−
3.19
1.9
# Points −− 1287 −− 27 −− 1086
# Labs 7 1 4

Mean 37.23 36.70 113.3 116.3 164.3 164.8
SD
CV
1 0.541
1.5
1.03
2.8
2 2.08
1.8
2.35
2.0
3 1.01
0.6
2.96
1.8
# Points 16 771 3 570 16 457
# Labs 1 14 1 10 1 10

Mean 35.35 35.80 115.9 115.6 160.6 162.3
SD
CV
1 0.695
2.0
1.11
3.1
2 1.48
1.3
1.49
1.3
3 1.93
1.2
2.75
1.7
# Points 87 1798 24 529 86 1683
# Labs 4 16 2 4 4 14

Mean 35.81 36.35 115.9 117.1 166.5 164.9
SD
CV
1 0.850
2.4
1.48
4.1
2 2.68
2.3
2.76
2.4
3 2.86
1.7
3.66
2.2
# Points 98 2759 91 1496 68 2027
# Labs 5 22 5 14 4 15

Mean 35.93 35.97 119.5 116.9 169.8 169.8
SD
CV
1 0.829
2.3
1.06
3.0
2 1.66
1.4
2.48
2.1
3 1.16
0.7
1.16
0.7
# Points 21 192 21 192 10 10
# Labs 3 6 3 6 1 1

Mean 38.00 38.00 118.5 118.5 169.0 169.0
SD
CV
1 0.000
0.0
0.000
0.0
2 0.707
0.6
0.707
0.6
3 1.41
0.8
1.41
0.8
# Points 2 2 2 2 2 2
# Labs 1 1 1 1 1 1

Mean −− 37.10 −− 118.0 −− 165.2
SD
CV
1 −−
−−
1.66
4.5
2 −−
−−
6.44
5.5
3 −−
−−
8.70
5.3
# Points −− 764 −− 756 −− 655
# Labs 2 2 2

Mean 34.55 36.45 115.3 115.9 −− 157.8
SD
CV
1 0.523
1.5
1.38
3.8
2 1.70
1.5
2.54
2.2
3 −−
−−
7.28
4.6
# Points 75 775 77 710 −− 409
# Labs 2 4 2 3 3

Mean −− 39.19 −− 118.4 −− 168.4
SD
CV
1 −−
−−
1.15
2.9
2 −−
−−
3.34
2.8
3 −−
−−
5.29
3.1
# Points −− 627 −− 623 −− 619
# Labs 1 1 1

Mean −− 38.26 −− −− −− 161.8
SD
CV
1 −−
−−
0.896
2.3
2 −−
−−
−−
−−
3 −−
−−
2.40
1.5
# Points −− 125 −− −− −− 125
# Labs 1 1

Mean −− 35.71 −− −− −− 162.2
SD
CV
1 −−
−−
1.35
3.8
2 −−
−−
−−
−−
3 −−
−−
5.12
3.2
# Points −− 757 −− −− −− 784
# Labs 2 2

Mean −− 38.07 −− 119.9 −− 171.3
SD
CV
1 −−
−−
0.918
2.4
2 −−
−−
1.44
1.2
3 −−
−−
2.03
1.2
# Points −− 250 −− 215 −− 267
# Labs 2 1 2

Mean −− 38.05 −− −− −− 165.1
SD
CV
1 −−
−−
3.10
8.2
2 −−
−−
−−
−−
3 −−
−−
8.20
5.0
# Points −− 225 −− −− −− 192
# Labs 1 1

Mean −− 37.70 −− −− −− 162.4
SD
CV
1 −−
−−
2.61
6.9
2 −−
−−
−−
−−
3 −−
−−
4.63
2.9
# Points −− 126 −− −− −− 127
# Labs 1 1

Mean −− 37.04 −− 118.3 −− 165.5
SD
CV
1 −−
−−
1.31
3.5
2 −−
−−
2.63
2.2
3 −−
−−
3.69
2.2
# Points −− 1759 −− 1661 −− 1653
# Labs 8 6 8

Mean −− 36.61 −− −− −− 168.5
SD
CV
1 −−
−−
0.640
1.7
2 −−
−−
−−
−−
3 −−
−−
1.39
0.8
# Points −− 113 −− −− −− 116
# Labs 2 2

Mean −− 37.40 −− −− −− 164.8
SD
CV
1 −−
−−
1.10
2.9
2 −−
−−
−−
−−
3 −−
−−
4.21
2.6
# Points −− 131 −− −− −− 126
# Labs 1 1
Method Group • G−glutamyl−p−nitroanilide−VITROS

Mean 35.40 36.71 116.9 118.3 163.8 165.7
SD
CV
1 1.33
3.8
1.50
4.1
2 2.98
2.6
3.38
2.9
3 4.63
2.8
4.64
2.8
# Points 679 31976 399 14941 432 28138
# Labs 31 254 23 132 21 208
Glucose Dipstick mg/dL

Mean −− 1.03 −− 2.11 −− −−
SD
CV
1 −−
−−
0.012
1.1
2 −−
−−
0.015
0.7
3 −−
−−
−−
−−
# Points −− 14 −− 14 −− −−
# Labs 1 1

Mean −− 59.08 −− 121.0 −− 357.1
SD
CV
1 −−
−−
0.976
1.7
2 −−
−−
1.21
1.0
3 −−
−−
3.83
1.1
# Points −− 47 −− 46 −− 47
# Labs 2 1 2
Method Group • Dipstick

Mean −− 45.76 −− 93.25 −− 357.1
SD
CV
1 −−
−−
24.62
53.8
2 −−
−−
50.71
54.4
3 −−
−−
3.83
1.1
# Points −− 61 −− 60 −− 47
# Labs 3 2 2
Glucose Electrochemical mg/dL

Mean −− 58.35 −− 116.0 −− −−
SD
CV
1 −−
−−
1.32
2.3
2 −−
−−
2.38
2.1
3 −−
−−
−−
−−
# Points −− 55 −− 50 −− −−
# Labs 1 1
Method Group • Electrochemical

Mean −− 58.35 −− 116.0 −− −−
SD
CV
1 −−
−−
1.32
2.3
2 −−
−−
2.38
2.1
3 −−
−−
−−
−−
# Points −− 55 −− 50 −− −−
# Labs 1 1
Glucose Glucose dehydrogenase mg/dL

Mean −− 57.66 −− 119.3 −− 365.9
SD
CV
1 −−
−−
0.543
0.9
2 −−
−−
2.09
1.7
3 −−
−−
6.63
1.8
# Points −− 66 −− 291 −− 287
# Labs 2 4 4

Mean −− 58.30 −− 117.6 −− 350.7
SD
CV
1 −−
−−
1.27
2.2
2 −−
−−
2.55
2.2
3 −−
−−
8.20
2.3
# Points −− 37 −− 37 −− 37
# Labs 1 1 1

Mean −− 58.90 −− 119.7 −− 354.8
SD
CV
1 −−
−−
1.07
1.8
2 −−
−−
2.19
1.8
3 −−
−−
7.09
2.0
# Points −− 557 −− 264 −− 549
# Labs 2 1 2

Mean 60.50 60.50 −− −− 360.5 360.5
SD
CV
1 0.280
0.5
0.280
0.5
2 −−
−−
−−
−−
3 0.000
0.0
0.000
0.0
# Points 2 2 −− −− 2 2
# Labs 1 1 1 1

Mean −− 61.41 −− 123.3 −− 361.5
SD
CV
1 −−
−−
1.61
2.6
2 −−
−−
1.97
1.6
3 −−
−−
10.85
3.0
# Points −− 90 −− 6 −− 114
# Labs 3 1 3
Method Group • Glucose dehydrogenase

Mean 60.50 59.07 −− 119.4 360.5 358.6
SD
CV
1 0.280
0.5
1.46
2.5
2 −−
−−
2.25
1.9
3 0.000
0.0
9.15
2.6
# Points 2 752 −− 598 2 989
# Labs 1 9 7 1 11
Glucose Glucose oxidase, hydrogen peroxide (Trinder) mg/dL

Mean 58.38 59.38 120.4 121.9 369.9 367.6
SD
CV
1 0.541
0.9
1.05
1.8
2 1.62
1.3
1.99
1.6
3 6.67
1.8
7.04
1.9
# Points 38 620 38 620 38 691
# Labs 1 1 1 1 1 2

Mean −− 60.95 −− 121.5 −− 359.3
SD
CV
1 −−
−−
2.02
3.3
2 −−
−−
3.46
2.8
3 −−
−−
8.36
2.3
# Points −− 1363 −− 1957 −− 1923
# Labs 2 4 4

Mean −− 62.77 −− 125.3 −− 366.1
SD
CV
1 −−
−−
1.34
2.1
2 −−
−−
2.45
2.0
3 −−
−−
7.45
2.0
# Points −− 538 −− 538 −− 538
# Labs 2 2 2

Mean −− −− −− 124.9 −− 363.0
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.66
2.1
3 −−
−−
10.77
3.0
# Points −− −− −− 167 −− 169
# Labs 1 1

Dirui CS Series
Mean −− 58.17 −− 115.3 −− 337.0
SD
CV
1 −−
−−
1.45
2.5
2 −−
−−
1.67
1.4
3 −−
−−
4.79
1.4
# Points −− 868 −− 861 −− 863
# Labs 2 2 2

Mean 58.93 58.72 118.5 118.2 329.2 340.8
SD
CV
1 3.26
5.5
3.01
5.1
2 4.26
3.6
4.93
4.2
3 7.01
2.1
14.52
4.3
# Points 30 476 28 373 5 43
# Labs 2 3 2 3 1 1
ERBA XL−640
Mean −− 59.99 −− 119.7 −− −−
SD
CV
1 −−
−−
1.23
2.1
2 −−
−−
1.61
1.3
3 −−
−−
−−
−−
# Points −− 58 −− 58 −− −−
# Labs 1 1

Mean −− −− −− 115.7 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.66
1.4
3 −−
−−
−−
−−
# Points −− −− −− 41 −− −−
# Labs 1
Fuji Dri−Chem Series • Fuji Dri−Chem GLU−PIII, REF 9903130

Mean 56.49 56.81 112.7 112.7 −− −−
SD
CV
1 2.38
4.2
2.51
4.4
2
5.01
4.4
5.26
4.7
3 −−
−−
−−
−−
# Points 59 329 59 328 −− −−
# Labs 3 4 3 4
ILab Series
Mean 57.91 61.67 118.9 125.2 −− −−
SD
CV
1 3.70
6.4
3.46
5.6
2 4.32
3.6
5.98
4.8
3 −−
−−
−−
−−
# Points 11 45 11 45 −− −−
# Labs 1 1 1 1
Mindray BS Series
Mean 58.92 57.85 118.7 116.7 351.2 345.3
SD
CV
1 0.721
1.2
1.35
2.3
2 1.62
1.4
2.70
2.3
3 5.59
1.6
7.58
2.2
# Points 21 155 21 154 21 154
# Labs 1 1 1 1 1 1
RANDOX RX imola
Mean 61.70 61.94 122.7 122.6 −− −−
SD
CV
1 0.731
1.2
0.793
1.3
2 1.09
0.9
1.45
1.2
3 −−
−−
−−
−−
# Points 26 228 24 197 −− −−
# Labs 1 1 1 1

Mean −− 59.49 −− 120.6 −− 359.9
SD
CV
1 −−
−−
1.23
2.1
2 −−
−−
2.39
2.0
3 −−
−−
6.98
1.9
# Points −− 231 −− 231 −− 231
# Labs 1 1 1

Mean 61.53 60.99 123.8 122.5 364.2 359.4
SD
CV
1 1.12
1.8
1.17
1.9
2 2.07
1.7
1.93
1.6
3 6.01
1.6
6.94
1.9
# Points 62 184 62 184 62 184
# Labs 2 2 2 2 2 2

Mean 62.34 61.17 123.6 122.6 363.4 360.0
SD
CV
1 0.541
0.9
1.03
1.7
2 0.901
0.7
2.09
1.7
3 1.98
0.5
6.56
1.8
# Points 31 186 31 186 31 186
# Labs 1 3 1 3 1 3
Mean −− −− −− 121.4 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
3.60
3.0
3 −−
−−
−−
−−
# Points −− −− −− 6 −− −−
# Labs 2

Mean 55.89 58.54 114.2 118.7 −− 355.0
SD
CV
1 1.24
2.2
1.77
3.0
2 2.26
2.0
2.81
2.4
3 −−
−−
6.39
1.8
# Points 37 181 37 228 −− 194
# Labs 1 3 1 4 3

Mean 59.38 59.09 116.0 117.1 −− 348.5
SD
CV
1 0.649
1.1
1.90
3.2
2 2.54
2.2
2.69
2.3
3 −−
−−
3.63
1.0
# Points 4 3519 4 3790 −− 14
# Labs 2 8 2 13 1
Toshiba−TBA
Mean −− −− −− −− −− 365.9
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
7.46
2.0
# Points −− −− −− −− −− 78
# Labs 1

Mean −− 58.24 −− 117.0 −− 338.9
SD
CV
1 −−
−−
1.30
2.2
2 −−
−−
2.30
2.0
3 −−
−−
4.98
1.5
# Points −− 445 −− 450 −− 472
# Labs 3 3 3

Mean 59.90 57.10 116.3 120.6 342.8 349.2
SD
CV
1 0.600
1.0
2.13
3.7
2 1.34
1.1
13.44
11.1
3 5.50
1.6
9.25
2.6
# Points 15 1343 35 1511 46 1534
# Labs 1 15 2 14 2 11

Mean −− 57.37 −− 122.9 −− 347.8
SD
CV
1 −−
−−
4.35
7.6
2 −−
−−
1.89
1.5
3 −−
−−
22.74
6.5
# Points −− 345 −− 74 −− 342
# Labs 2 1 2

Mean −− 60.30 −− −− −− 354.6
SD
CV
1 −−
−−
0.853
1.4
2 −−
−−
−−
−−
3 −−
−−
2.74
0.8
# Points −− 63 −− −− −− 62
# Labs 1 1

Mean −− 51.77 −− 118.0 −− 325.1
SD
CV
1 −−
−−
12.90
24.9
2 −−
−−
1.88
1.6
3 −−
−−
77.91
24.0
# Points −− 269 −− 147 −− 287
# Labs 3 1 3

Mean −− 55.57 −− −− −− 337.1
SD
CV
1 −−
−−
2.70
4.9
2 −−
−−
−−
−−
3 −−
−−
12.01
3.6
# Points −− 429 −− −− −− 409
# Labs 3 3

Mean −− 55.20 −− −− −− 334.1
SD
CV
1 −−
−−
1.63
2.9
2 −−
−−
−−
−−
3 −−
−−
6.27
1.9
# Points −− 202 −− −− −− 140
# Labs 3 2

Mean −− 56.23 −− 118.3 −− 344.3
SD
CV
1 −−
−−
2.03
3.6
2 −−
−−
2.76
2.3
3 −−
−−
8.35
2.4
# Points −− 1733 −− 326 −− 1425
# Labs 14 6 13

Mean −− 57.30 −− 120.4 −− 351.5
SD
CV
1 −−
−−
1.65
2.9
2 −−
−−
2.93
2.4
3 −−
−−
6.75
1.9
# Points −− 3305 −− 3316 −− 4240
# Labs 20 16 26

Mean −− 58.75 −− 122.5 −− 349.5
SD
CV
1 −−
−−
2.26
3.8
2 −−
−−
2.20
1.8
3 −−
−−
7.42
2.1
# Points −− 5565 −− 1694 −− 4568
# Labs 60 18 57

Mean −− 57.53 −− 121.0 −− 351.5
SD
CV
1 −−
−−
1.56
2.7
2 −−
−−
2.33
1.9
3 −−
−−
7.51
2.1
# Points −− 3919 −− 783 −− 3387
# Labs 31 8 27

Mean −− 57.02 −− 121.4 −− 350.3
SD
CV
1 −−
−−
1.60
2.8
2 −−
−−
2.47
2.0
3 −−
−−
7.50
2.1
# Points −− 7514 −− 3533 −− 7162
# Labs 75 31 71

Mean −− 57.78 −− 121.0 −− 351.9
SD
CV
1 −−
−−
1.55
2.7
2 −−
−−
2.65
2.2
3 −−
−−
8.37
2.4
# Points −− 8000 −− 3468 −− 7957
# Labs 63 29 62

Mean 56.51 58.61 −− 120.3 348.9 357.5
SD
CV
1 1.47
2.6
2.33
4.0
2 −−
−−
2.42
2.0
3 6.27
1.8
9.22
2.6
# Points 32 1941 −− 527 35 1919
# Labs 1 12 7 1 12

Mean 55.96 57.29 −− 120.5 345.7 349.8
SD
CV
1 0.820
1.5
1.84
3.2
2 −−
−−
1.60
1.3
3 2.68
0.8
6.19
1.8
# Points 22 5111 −− 2182 22 5286
# Labs 1 32 16 1 34

Mean 58.09 57.41 121.4 121.8 348.7 348.0
SD
CV
1 2.28
3.9
1.83
3.2
2 0.959
0.8
2.68
2.2
3 5.35
1.5
6.70
1.9
# Points 183 5892 62 2256 156 5361
# Labs 7 49 2 20 7 47

Mean 58.97 58.23 121.5 120.9 348.2 348.9
SD
CV
1 1.34
2.3
1.45
2.5
2 2.42
2.0
2.66
2.2
3 5.81
1.7
6.00
1.7
# Points 84 4344 68 1228 33 3980
# Labs 7 43 4 15 4 39

Mean 57.26 58.64 −− 120.6 335.1 349.3
SD
CV
1 0.671
1.2
1.55
2.6
2 −−
−−
1.31
1.1
3 3.33
1.0
6.40
1.8
# Points 31 2874 −− 698 32 2891
# Labs 1 30 3 1 29

Mean −− 58.34 −− 122.0 −− 353.1
SD
CV
1 −−
−−
1.48
2.5
2 −−
−−
2.59
2.1
3 −−
−−
7.55
2.1
# Points −− 5262 −− 2373 −− 4743
# Labs 40 16 35

Mean 56.96 57.35 119.3 118.7 343.5 346.0
SD
CV
1 2.44
4.3
1.64
2.9
2 4.32
3.6
3.02
2.5
3 9.12
2.7
7.63
2.2
# Points 85 9839 44 3571 90 9218
# Labs 5 91 2 36 5 75

Mean 57.16 57.51 115.7 116.9 338.9 342.0
SD
CV
1 1.62
2.8
1.57
2.7
2 2.69
2.3
2.58
2.2
3 5.30
1.6
5.55
1.6
# Points 196 3089 75 1347 154 2301
# Labs 10 39 6 21 6 27

Mean −− 58.36 −− −− −− 339.1
SD
CV
1 −−
−−
2.03
3.5
2 −−
−−
−−
−−
3 −−
−−
21.76
6.4
# Points −− 384 −− −− −− 429
# Labs 2 2

Mean 56.45 56.56 116.8 117.6 341.8 342.5
SD
CV
1 1.35
2.4
1.63
2.9
2 1.83
1.6
2.44
2.1
3 5.90
1.7
6.98
2.0
# Points 238 2009 219 1314 114 1705
# Labs 14 25 9 16 8 19

Mean 57.53 57.36 115.3 115.4 337.5 337.6
SD
CV
1 1.41
2.4
1.39
2.4
2 1.98
1.7
2.14
1.9
3 6.12
1.8
5.92
1.8
# Points 196 352 81 162 166 285
# Labs 10 11 6 6 8 10

Mean 57.50 57.11 118.8 119.1 339.7 341.7
SD
CV
1 1.79
3.1
1.94
3.4
2 2.63
2.2
3.04
2.6
3 6.36
1.9
8.14
2.4
# Points 340 1561 120 786 333 1517
# Labs 13 14 4 5 12 13

Mean 56.60 56.91 115.7 115.7 344.8 344.5
SD
CV
1 2.10
3.7
1.95
3.4
2 2.47
2.1
2.47
2.1
3 8.14
2.4
7.21
2.1
# Points 179 243 59 59 130 194
# Labs 9 9 4 4 6 6

Mean 57.53 56.86 118.2 117.2 340.5 336.7
SD
CV
1 1.99
3.5
1.38
2.4
2 2.29
1.9
1.75
1.5
3 3.76
1.1
4.61
1.4
# Points 97 356 90 345 98 363
# Labs 6 6 3 3 6 6

Mean 56.66 56.36 118.0 117.9 −− 339.6
SD
CV
1 0.591
1.0
1.87
3.3
2 0.793
0.7
1.23
1.0
3 −−
−−
2.25
0.7
# Points 33 434 34 387 −− 48
# Labs 1 2 1 1 1

Mean −− 59.85 −− −− −− 360.7
SD
CV
1 −−
−−
0.969
1.6
2 −−
−−
−−
−−
3 −−
−−
3.50
1.0
# Points −− 60 −− −− −− 59
# Labs 1 1

Mean −− 55.22 −− −− −− 349.2
SD
CV
1 −−
−−
4.06
7.3
2 −−
−−
−−
−−
3 −−
−−
4.22
1.2
# Points −− 430 −− −− −− 440
# Labs 2 2

Mean 57.45 57.07 119.4 117.6 −− −−
SD
CV
1 0.605
1.1
0.817
1.4
2 1.01
0.8
2.26
1.9
3 −−
−−
−−
−−
# Points 43 307 43 305 −− −−
# Labs 1 1 1 1

Mean −− 53.58 −− −− −− 346.4
SD
CV
1 −−
−−
2.56
4.8
2 −−
−−
−−
−−
3 −−
−−
3.23
0.9
# Points −− 120 −− −− −− 120
# Labs 1 1

Mean −− 52.80 −− −− −− 337.2
SD
CV
1 −−
−−
2.96
5.6
2 −−
−−
−−
−−
3 −−
−−
10.95
3.2
# Points −− 119 −− −− −− 122
# Labs 2 2

Mean −− 57.20 −− −− −− 349.4
SD
CV
1 −−
−−
0.734
1.3
2 −−
−−
−−
−−
3 −−
−−
3.57
1.0
# Points −− 52 −− −− −− 60
# Labs 1 1

Mean −− 52.49 −− 120.7 −− 343.9
SD
CV
1 −−
−−
1.06
2.0
2 −−
−−
2.39
2.0
3 −−
−−
9.32
2.7
# Points −− 104 −− 112 −− 180
# Labs 1 2 3

Mean −− 57.91 −− −− −− 359.7
SD
CV
1 −−
−−
0.933
1.6
2 −−
−−
−−
−−
3 −−
−−
3.69
1.0
# Points −− 16 −− −− −− 15
# Labs 1 1

Mean −− 55.04 −− −− −− 335.3
SD
CV
1 −−
−−
0.977
1.8
2 −−
−−
−−
−−
3 −−
−−
2.95
0.9
# Points −− 148 −− −− −− 152
# Labs 1 1

Mean −− 55.61 −− 112.4 −− 337.1
SD
CV
1 −−
−−
2.13
3.8
2 −−
−−
1.17
1.0
3 −−
−−
5.21
1.5
# Points −− 190 −− 83 −− 193
# Labs 3 1 4

Mean −− 54.11 −− −− −− 339.7
SD
CV
1 −−
−−
3.01
5.6
2 −−
−−
−−
−−
3 −−
−−
5.54
1.6
# Points −− 539 −− −− −− 585
# Labs 6 6

Mean −− 57.12 −− 113.3 −− 342.7
SD
CV
1 −−
−−
2.46
4.3
2 −−
−−
2.37
2.1
3 −−
−−
9.67
2.8
# Points −− 1161 −− 260 −− 1127
# Labs 6 1 6

Mean −− 57.13 −− −− −− 336.4
SD
CV
1 −−
−−
0.823
1.4
2 −−
−−
−−
−−
3 −−
−−
4.51
1.3
# Points −− 140 −− −− −− 134
# Labs 2 2

Mean −− 55.40 −− −− −− 339.6
SD
CV
1 −−
−−
1.19
2.2
2 −−
−−
−−
−−
3 −−
−−
1.45
0.4
# Points −− 23 −− −− −− 23
# Labs 1 1
Method Group • Glucose oxidase, hydrogen peroxide (Trinder)

Mean 57.58 57.74 118.1 120.0 343.9 349.1
SD
CV
1 2.15
3.7
2.10
3.6
2
3.68
3.1
4.22
3.5
3 9.79
2.8
9.18
2.6
# Points 2093 88404 1245 43159 1566 80418
# Labs 102 757 59 348 73 687
Glucose Glucose oxidase, oxygen consumption mg/dL

Mean −− 58.70 −− 118.0 −− 349.5
SD
CV
1 −−
−−
1.48
2.5
2 −−
−−
2.43
2.1
3 −−
−−
9.68
2.8
# Points −− 1669 −− 1584 −− 1876
# Labs 5 3 6

Mean −− 57.53 −− 115.1 −− 340.3
SD
CV
1 −−
−−
1.39
2.4
2 −−
−−
2.44
2.1
3 −−
−−
7.01
2.1
# Points −− 103 −− 103 −− 103
# Labs 1 1 1
Glucose Glucose oxidase, oxygen consumption mg/dL

Mean 56.00 57.60 −− 116.8 −− 347.6
SD
CV
1 2.00
3.6
2.18
3.8
2 −−
−−
3.29
2.8
3 −−
−−
6.50
1.9
# Points 26 9053 −− 2876 −− 8175
# Labs 1 21 10 18

Mean −− 55.25 −− 113.9 −− 338.1
SD
CV
1 −−
−−
2.11
3.8
2 −−
−−
3.24
2.8
3 −−
−−
8.73
2.6
# Points −− 41 −− 52 −− 53
# Labs 1 1 1

Mean 59.88 60.89 119.6 121.5 −− 326.0
SD
CV
1 2.29
3.8
2.98
4.9
2 4.38
3.7
5.81
4.8
3 −−
−−
0.000
0.0
# Points 24 201 12 170 −− 1
# Labs 1 1 1 1 1

Mean −− 58.13 −− −− −− 352.4
SD
CV
1 −−
−−
2.17
3.7
2 −−
−−
−−
−−
3 −−
−−
12.88
3.7
# Points −− 335 −− −− −− 334
# Labs 1 1
Method Group • Glucose oxidase, oxygen consumption

Mean 57.86 57.83 119.6 117.3 −− 348.0
SD
CV
1 2.89
5.0
2.18
3.8
2 4.38
3.7
3.32
2.8
3 −−
−−
7.60
2.2
# Points 50 11401 12 4785 −− 10545
# Labs 2 30 1 16 28
Glucose Glucose oxidase, Polarography mg/dL

Mean 60.36 58.37 118.9 116.1 −− −−
SD
CV
1 0.987
1.6
1.32
2.3
2 1.27
1.1
2.32
2.0
3 −−
−−
−−
−−
# Points 6 122 5 119 −− −−
# Labs 1 2 1 2

Mean −− −− −− 126.1 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.42
1.9
3 −−
−−
−−
−−
# Points −− −− −− 179 −− −−
# Labs 1
Method Group • Glucose oxidase, Polarography

Mean 60.36 58.37 118.9 122.1 −− −−
SD
CV
1 0.987
1.6
1.32
2.3
2 1.27
1.1
5.41
4.4
3 −−
−−
−−
−−
# Points 6 122 5 298 −− −−
# Labs 1 2 1 3
Glucose Hexokinase mg/dL

1drop
Mean −− 57.05 −− 116.7 −− −−
SD
CV
1 −−
−−
0.653
1.1
2 −−
−−
1.55
1.3
3 −−
−−
−−
−−
# Points −− 22 −− 22 −− −−
# Labs 1 1

Mean 63.06 64.70 117.1 120.0 −− 350.6
SD
CV
1 0.000
0.0
1.19
1.8
2 0.000
0.0
2.83
2.4
3 −−
−−
5.17
1.5
# Points 1 103 1 20 −− 78
# Labs 1 2 1 1 2

Mean 57.18 57.87 116.4 118.3 353.8 360.3
SD
CV
1 1.18
2.1
1.12
1.9
2 2.27
1.9
2.33
2.0
3 7.79
2.2
7.45
2.1
# Points 2380 81054 1561 44596 1512 76755
# Labs 79 252 65 167 46 197
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH Glucose REF 3L82

Mean 57.50 57.41 117.0 117.0 −− −−
SD
CV
1 0.989
1.7
0.883
1.5
2
1.53
1.3
1.56
1.3
3 −−
−−
−−
−−
# Points 38 218 38 218 −− −−
# Labs 2 2 2 2
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c Glucose, REF 07P55

Mean −− 57.82 −− 117.0 −− 359.6
SD
CV
1 −−
−−
1.03
1.8
2 −−
−−
0.845
0.7
3 −−
−−
5.60
1.6
# Points −− 311 −− 73 −− 231
# Labs 3 2 1

Mean −− 58.82 −− 119.4 −− 353.5
SD
CV
1 −−
−−
0.980
1.7
2 −−
−−
2.10
1.8
3 −−
−−
5.98
1.7
# Points −− 246 −− 267 −− 267
# Labs 1 1 1

Mean −− −− −− 121.9 −− 359.3
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.48
2.0
3 −−
−−
7.59
2.1
# Points −− −− −− 575 −− 576
# Labs 2 2

Mean 57.96 58.48 116.5 118.4 345.9 350.2
SD
CV
1 1.50
2.6
1.80
3.1
2 3.07
2.6
3.47
2.9
3 7.86
2.3
10.31
2.9
# Points 2301 121K 1953 90982 1333 125K
# Labs 76 337 63 253 44 322

Mean −− 58.52 −− 118.0 −− 352.3
SD
CV
1 −−
−−
1.43
2.4
2 −−
−−
3.34
2.8
3 −−
−−
7.35
2.1
# Points −− 700 −− 973 −− 687
# Labs 6 8 6

Mean −− 59.91 −− −− −− 358.5
SD
CV
1 −−
−−
2.07
3.5
2 −−
−−
−−
−−
3 −−
−−
18.11
5.1
# Points −− 214 −− −− −− 214
# Labs 1 1
Beckman Coulter AU Series • MedicalSystem Biotechnology Angiotensin Converting Enzyme Kit

Mean 60.18 60.48 −− −− −− −−
SD
CV
1 0.738
1.2
0.932
1.5
−−
−−
2 −−
−−
3 −−
−−
−−
−−
# Points 62 690 −− −− −− −−
# Labs 2 2

Mean −− −− 120.4 121.8 365.0 361.2
SD
CV
1 −−
−−
−−
−−
2 1.62
1.3
3.68
3.0
3 3.42
0.9
11.13
3.1
# Points −− −− 5 730 4 732
# Labs 1 2 1 2

Mean 57.97 58.59 −− 118.3 348.9 351.8
SD
CV
1 1.12
1.9
1.37
2.3
2 −−
−−
2.66
2.2
3 4.12
1.2
7.03
2.0
# Points 35 3763 −− 260 34 3766
# Labs 1 12 2 1 12

Mean −− −− 116.7 117.1 343.6 347.5
SD
CV
1 −−
−−
−−
−−
2 3.69
3.2
4.30
3.7
3 13.19
3.8
17.79
5.1
# Points −− −− 43 248 41 245
# Labs 3 3 3 3

Mean −− 57.37 −− −− −− −−
SD
CV
1 −−
−−
1.44
2.5
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 25 −− −− −− −−
# Labs 1

Mean −− 59.42 −− 119.2 −− 354.6
SD
CV
1 −−
−−
1.68
2.8
2 −−
−−
2.90
2.4
3 −−
−−
8.03
2.3
# Points −− 4886 −− 2908 −− 4780
# Labs 13 7 13

Mean −− −− −− 122.2 −− 359.7
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.16
1.8
3 −−
−−
7.36
2.0
# Points −− −− −− 107 −− 107
# Labs 1 1

Mean −− 58.25 −− −− −− 353.9
SD
CV
1 −−
−−
1.10
1.9
2 −−
−−
−−
−−
3 −−
−−
6.95
2.0
# Points −− 90 −− −− −− 92
# Labs 1 1

Mean −− −− 115.3 116.9 −− 347.0
SD
CV
1 −−
−−
−−
−−
2
0.901
0.8
1.49
1.3
3 −−
−−
3.46
1.0
# Points −− −− 23 184 −− 171
# Labs 1 1 1

Mean −− 58.41 −− −− −− 351.8
SD
CV
1 −−
−−
1.19
2.0
2 −−
−−
−−
−−
3 −−
−−
6.26
1.8
# Points −− 399 −− −− −− 389
# Labs 2 2

Mean −− 58.63 −− 116.7 −− 347.7
SD
CV
1 −−
−−
2.87
4.9
2 −−
−−
5.46
4.7
3 −−
−−
15.66
4.5
# Points −− 252 −− 194 −− 254
# Labs 2 1 2

Mindray BS Series
Mean −− 59.45 −− 121.8 −− 360.8
SD
CV
1 −−
−−
1.08
1.8
2 −−
−−
2.18
1.8
3 −−
−−
6.64
1.8
# Points −− 315 −− 331 −− 332
# Labs 2 1 1

Mean −− −− −− 114.5 −− 339.7
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.63
1.4
3 −−
−−
3.79
1.1
# Points −− −− −− 148 −− 148
# Labs 1 1
Mindray CL Series
Mean −− −− −− 120.1 −− 353.3
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.21
1.8
3 −−
−−
7.77
2.2
# Points −− −− −− 363 −− 361
# Labs 3 3
RANDOX RX daytona
Mean 63.00 60.58 126.0 124.2 365.0 365.0
SD
CV
1 3.36
5.3
5.29
8.7
2 6.81
5.4
8.60
6.9
3 0.000
0.0
0.000
0.0
# Points 20 204 16 168 1 1
# Labs 1 1 1 1 1 1

Mean 58.74 59.64 119.0 120.5 351.0 356.6
SD
CV
1 1.46
2.5
1.50
2.5
2 2.78
2.3
2.81
2.3
3 8.11
2.3
7.87
2.2
# Points 2750 90457 395 38107 2769 96216
# Labs 51 203 11 110 50 215
Roche cobas 6000/8000/c 311 • 3rd Generation

Mean −− 60.01 −− 121.3 −− 357.4
SD
CV
1 −−
−−
1.38
2.3
2 −−
−−
2.74
2.3
3 −−
−−
7.33
2.1
# Points −− 1754 −− 1755 −− 1765
# Labs 4 4 4

Mean 58.70 59.57 118.7 120.9 354.9 359.5
SD
CV
1 0.797
1.4
1.12
1.9
2 2.19
1.8
2.25
1.9
3 3.78
1.1
6.08
1.7
# Points 270 7454 226 6802 125 6440
# Labs 7 21 5 16 5 20
Roche cobas c 303/503 • Roche GLUC3, REF 08057800

Mean 58.88 59.30 118.4 120.3 352.7 356.4
SD
CV
1 1.24
2.1
1.12
1.9
2 1.03
0.9
1.48
1.2
3 8.20
2.3
6.60
1.9
# Points 372 11310 155 2887 241 11302
# Labs 11 35 4 10 8 32

Mean 58.70 58.34 120.3 118.9 359.8 359.1
SD
CV
1 2.52
4.3
1.58
2.7
2 3.11
2.6
3.20
2.7
3 6.92
1.9
5.76
1.6
# Points 190 2402 193 4549 66 1081
# Labs 3 4 3 4 2 4

Mean 59.02 60.30 117.0 121.5 348.6 356.8
SD
CV
1 1.20
2.0
1.44
2.4
2 2.00
1.7
2.86
2.3
3 4.99
1.4
8.07
2.3
# Points 89 4938 32 2153 89 4918
# Labs 3 13 1 4 3 13

Roche cobas Integra / c 111 • 3rd Generation
Mean −− 61.72 −− −− −− 368.4
SD
CV
1 −−
−−
2.65
4.3
2 −−
−−
−−
−−
3 −−
−−
14.17
3.8
# Points −− 150 −− −− −− 150
# Labs 1 1
Roche cobas Integra / c 111 • Roche

Mean 60.57 61.04 122.4 123.1 −− −−
SD
CV
1 0.746
1.2
1.16
1.9
2 1.46
1.2
2.36
1.9
3 −−
−−
−−
−−
# Points 7 533 7 533 −− −−
# Labs 1 1 1 1

Mean −− 59.36 −− 118.4 −− 355.6
SD
CV
1 −−
−−
1.98
3.3
2 −−
−−
3.67
3.1
3 −−
−−
7.43
2.1
# Points −− 765 −− 761 −− 664
# Labs 4 4 3

Mean −− 59.52 −− 121.9 −− 364.1
SD
CV
1 −−
−−
1.27
2.1
2 −−
−−
1.98
1.6
3 −−
−−
5.78
1.6
# Points −− 630 −− 631 −− 630
# Labs 2 2 2

Mean −− −− −− 116.9 −− 347.2
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.25
1.9
3 −−
−−
6.56
1.9
# Points −− −− −− 186 −− 188
# Labs 1 1
Mean −− 59.70 −− 123.3 −− 366.8
SD
CV
1 −−
−−
1.95
3.3
2 −−
−−
4.37
3.5
3 −−
−−
16.60
4.5
# Points −− 273 −− 388 −− 389
# Labs 1 2 2

Mean −− 60.54 −− −− −− 357.4
SD
CV
1 −−
−−
0.967
1.6
2 −−
−−
−−
−−
3 −−
−−
5.32
1.5
# Points −− 279 −− −− −− 279
# Labs 1 1

Mean −− −− −− 115.6 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.74
1.5
3 −−
−−
−−
−−
# Points −− −− −− 24 −− −−
# Labs 1

Mean 57.10 57.92 114.4 116.4 339.3 345.4
SD
CV
1 2.06
3.6
1.46
2.5
2 6.09
5.3
2.65
2.3
3 8.89
2.6
7.35
2.1
# Points 111 16482 75 11946 90 15947
# Labs 4 37 3 28 3 33

Mean −− 59.26 −− 117.5 −− 351.8
SD
CV
1 −−
−−
2.61
4.4
2 −−
−−
3.84
3.3
3 −−
−−
9.53
2.7
# Points −− 514 −− 509 −− 521
# Labs 2 2 2

Siemens ADVIA Chemistry Systems • LEADMAN
Mean −− −− 121.3 120.8 356.2 356.5
SD
CV
1 −−
−−
−−
−−
2 1.62
1.3
3.13
2.6
3 5.95
1.7
8.08
2.3
# Points −− −− 36 538 33 525
# Labs 1 2 1 2

Mean 58.67 59.33 116.6 117.7 342.7 345.7
SD
CV
1 1.16
2.0
1.34
2.3
2 1.79
1.5
2.42
2.1
3 5.92
1.7
6.58
1.9
# Points 521 33286 442 17549 236 28149
# Labs 15 93 13 58 10 81
Siemens Atellica CH Analyzer • Siemens Atellica CH GluH_3, REF 11097592

Mean −− 58.30 −− −− −− 341.1
SD
CV
1 −−
−−
0.761
1.3
−−
−−
2 −−
−−
3 −−
−−
3.32
1.0
# Points −− 89 −− −− −− 89
# Labs 1 1

Mean 59.94 60.47 122.6 122.8 349.7 355.3
SD
CV
1 1.74
2.9
1.70
2.8
2 3.20
2.6
2.79
2.3
3 7.65
2.2
7.45
2.1
# Points 1784 113K 428 19902 1647 104K
# Labs 58 267 16 67 51 235

Mean 60.68 60.85 122.5 122.9 349.1 352.6
SD
CV
1 1.82
3.0
1.83
3.0
2 3.62
3.0
3.47
2.8
3 9.03
2.6
9.07
2.6
# Points 3439 279K 1087 83902 2964 256K
# Labs 91 484 32 143 79 457

Mean −− −− 120.7 119.9 −− −−
SD
CV
1 −−
−−
−−
−−
2 3.21
2.7
3.40
2.8
3 −−
−−
−−
−−
# Points −− −− 23 32 −− −−
# Labs 1 1

Mean −− 61.45 −− 122.3 −− 357.1
SD
CV
1 −−
−−
1.22
2.0
2 −−
−−
2.54
2.1
3 −−
−−
7.19
2.0
# Points −− 107 −− 107 −− 107
# Labs 1 1 1
Toshiba−TBA
Mean 57.50 58.67 −− −− 360.0 352.0
SD
CV
1 0.710
1.2
0.620
1.1
2 −−
−−
−−
−−
3 0.000
0.0
3.99
1.1
# Points 2 362 −− −− 1 360
# Labs 1 1 1 1
Method Group • Hexokinase

Mean 58.97 59.77 118.3 120.0 349.9 353.7
SD
CV
1 2.00
3.4
2.00
3.3
2 3.88
3.3
3.76
3.1
3 8.61
2.5
9.32
2.6
# Points 14372 778K 6739 336K 11186 744K
# Labs 407 1816 228 919 309 1685
Haptoglobin Immunonephelometric, fixed time, kinetic mg/dL

Mean 79.60 79.65 −− 115.8 142.5 142.8
SD
CV
1 1.61
2.0
2.81
3.5
2 −−
−−
4.39
3.8
3 4.14
2.9
5.76
4.0
# Points 60 4997 −− 1244 13 4415
# Labs 1 11 4 1 11
Haptoglobin Immunonephelometric, fixed time, kinetic mg/dL

Mean 79.60 79.65 −− 115.8 142.5 142.8
SD
CV
1 1.61
2.0
2.81
3.5
2 −−
−−
4.39
3.8
3 4.14
2.9
5.76
4.0
# Points 60 4997 −− 1244 13 4415
# Labs 1 11 4 1 11
Haptoglobin Immunoturbidimetric mg/dL

Abbott Alinity c
Mean −− 80.61 −− 152.3 −− 143.4
SD
CV
1 −−
−−
1.24
1.5
2 −−
−−
17.05
11.2
3 −−
−−
1.92
1.3
# Points −− 296 −− 119 −− 301
# Labs 1 2 1

Mean −− 78.20 −− −− −− −−
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 1 −− −− −− −−
# Labs 1

Mean −− 77.20 −− −− −− 138.2
SD
CV
1 −−
−−
1.15
1.5
2 −−
−−
−−
−−
3 −−
−−
1.77
1.3
# Points −− 20 −− −− −− 20
# Labs 1 1

Mean 81.59 78.22 118.9 113.4 140.5 137.7
SD
CV
1 1.98
2.4
2.48
3.2
2 1.50
1.3
3.26
2.9
3 2.65
1.9
3.48
2.5
# Points 37 2629 17 1003 36 2589
# Labs 2 11 1 5 2 11

Mean 80.74 79.61 −− 114.6 141.2 139.0
SD
CV
1 3.36
4.2
2.75
3.5
2 −−
−−
2.77
2.4
3 3.75
2.7
3.57
2.6
# Points 58 1741 −− 944 50 1761
# Labs 2 6 5 2 6
Roche cobas c 303/503 • Roche HAPT2, REF 08106045

Mean −− 7782 −− −− −− 13482
SD
CV
1 −−
−−
72.39
0.9
2 −−
−−
−−
−−
3 −−
−−
60.30
0.4
# Points −− 10 −− −− −− 11
# Labs 1 1

Mean −− 77.82 −− 114.8 −− 140.5
SD
CV
1 −−
−−
2.08
2.7
2 −−
−−
3.80
3.3
3 −−
−−
2.43
1.7
# Points −− 13 −− 13 −− 13
# Labs 1 1 1

Mean −− 76.91 −− −− −− 133.0
SD
CV
1 −−
−−
3.00
3.9
2 −−
−−
−−
−−
3 −−
−−
6.00
4.5
# Points −− 753 −− −− −− 736
# Labs 2 2

Mean −− 81.58 −− 120.1 −− 145.3
SD
CV
1 −−
−−
2.14
2.6
2 −−
−−
3.52
2.9
3 −−
−−
4.20
2.9
# Points −− 358 −− 356 −− 353
# Labs 1 1 1
Haptoglobin Immunoturbidimetric mg/dL

Mean 81.07 78.79 118.9 116.8 140.9 138.3
SD
CV
1 2.92
3.6
2.84
3.6
2 1.50
1.3
9.66
8.3
3 3.34
2.4
4.84
3.5
# Points 95 5821 17 2435 86 5784
# Labs 4 25 1 14 4 24
IgA FIA mg/dL

Mean −− 121.4 −− 172.5 −− 207.3
SD
CV
1 −−
−−
2.72
2.2
2 −−
−−
3.00
1.7
3 −−
−−
5.52
2.7
# Points −− 81 −− 81 −− 81
# Labs 1 1 1
Method Group • FIA

Mean −− 121.4 −− 172.5 −− 207.3
SD
CV
1 −−
−−
2.72
2.2
2 −−
−−
3.00
1.7
3 −−
−−
5.52
2.7
# Points −− 81 −− 81 −− 81
# Labs 1 1 1
IgA Immunonephelometric, end point mg/dL

Mean −− −− −− −− 194.2 196.4
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 4.86
2.5
6.04
3.1
# Points −− −− −− −− 85 804
# Labs 2 2

Mean −− −− −− −− 194.2 196.4
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 4.86
2.5
6.04
3.1
# Points −− −− −− −− 85 804
# Labs 2 2
IgA Immunonephelometric, fixed time, kinetic mg/dL

Mean −− 116.4 −− 168.2 −− 205.5
SD
CV
1 −−
−−
3.71
3.2
2 −−
−−
4.07
2.4
3 −−
−−
4.22
2.1
# Points −− 591 −− 926 −− 510
# Labs 1 1 1

Mean 130.1 126.9 188.1 184.0 234.9 227.7
SD
CV
1 2.86
2.2
4.95
3.9
2 3.83
2.0
6.35
3.5
3 5.68
2.4
8.93
3.9
# Points 95 4945 33 2461 45 3860
# Labs 2 9 1 5 2 8

Mean 130.1 125.8 188.1 179.7 234.9 225.1
SD
CV
1 2.86
2.2
5.82
4.6
3.83
2.0
2 9.12
5.1
3 5.68
2.4
11.10
4.9
# Points 95 5536 33 3387 45 4370
# Labs 2 10 1 6 2 9
IgA Immunonephelometric, kinetic mg/dL

Mean 114.3 112.5 169.9 167.3 −− −−
SD
CV
1 7.10
6.2
3.73
3.3
2 8.70
5.1
4.45
2.7
3 −−
−−
−−
−−
# Points 83 981 88 989 −− −−
# Labs 1 1 1 1
IgA Immunonephelometric, kinetic mg/dL

Mean 114.3 112.5 169.9 167.3 −− −−
SD
CV
1 7.10
6.2
3.73
3.3
2 8.70
5.1
4.45
2.7
3 −−
−−
−−
−−
# Points 83 981 88 989 −− −−
# Labs 1 1 1 1
IgA Immunoturbidimetric mg/dL

Mean 116.3 119.8 164.0 167.9 −− 206.9
SD
CV
1 5.14
4.4
4.84
4.0
2 4.94
3.0
6.36
3.8
3 −−
−−
6.20
3.0
# Points 182 1479 181 981 −− 526
# Labs 9 13 9 13 4
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c IgA, REF 09P61

Mean −− 118.2 −− 166.4 −− −−
SD
CV
1 −−
−−
2.98
2.5
2 −−
−−
5.40
3.2
3 −−
−−
−−
−−
# Points −− 75 −− 75 −− −−
# Labs 1 1

Mean 122.8 122.1 168.4 170.7 203.9 201.3
SD
CV
1 2.27
1.8
3.71
3.0
2 2.31
1.4
4.79
2.8
3 3.59
1.8
6.31
3.1
# Points 121 5517 24 3297 89 5295
# Labs 4 15 1 10 3 13

Mean −− 122.2 −− −− −− 203.5
SD
CV
1 −−
−−
2.03
1.7
2 −−
−−
−−
−−
3 −−
−−
3.82
1.9
# Points −− 102 −− −− −− 102
# Labs 1 1
Hitachi Chemistry Series • Nittobo

Mean −− 118.4 −− −− −− −−
SD
CV
1 −−
−−
7.35
6.2
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 70 −− −− −− −−
# Labs 1

Mean 115.6 118.3 169.2 171.2 −− 211.9
SD
CV
1 3.19
2.8
4.54
3.8
2 3.88
2.3
5.79
3.4
3 −−
−−
6.88
3.2
# Points 58 1700 58 1040 −− 1972
# Labs 2 8 2 6 7

Mean −− 124.2 −− 176.8 −− 213.7
SD
CV
1 −−
−−
4.98
4.0
2 −−
−−
8.74
4.9
3 −−
−−
11.78
5.5
# Points −− 1122 −− 1131 −− 1147
# Labs 6 6 6

Mean −− −− −− 167.5 −− 206.1
SD
CV
1 −−
−−
−−
−−
2 −−
−−
4.87
2.9
3 −−
−−
5.71
2.8
# Points −− −− −− 272 −− 271
# Labs 1 1

Mean −− 130.0 −− 188.4 −− 226.6
SD
CV
1 −−
−−
4.45
3.4
2 −−
−−
4.35
2.3
3 −−
−−
6.11
2.7
# Points −− 1473 −− 1060 −− 1203
# Labs 4 3 4
IgA Immunoturbidimetric mg/dL

Mean −− 113.4 −− 170.2 −− 211.3
SD
CV
1 −−
−−
3.36
3.0
2 −−
−−
4.40
2.6
3 −−
−−
5.04
2.4
# Points −− 66 −− 68 −− 67
# Labs 1 1 1

Mean 127.8 133.5 179.5 189.3 211.8 225.9
SD
CV
1 4.56
3.6
4.04
3.0
2 4.51
2.5
5.70
3.0
3 11.09
5.2
8.81
3.9
# Points 26 804 26 799 57 844
# Labs 1 3 1 3 2 4
The Binding Site

Mean −− 120.1 −− 168.7 −− 205.1
SD
CV
1 −−
−−
3.44
2.9
2 −−
−−
6.99
4.1
3 −−
−−
3.50
1.7
# Points −− 44 −− 43 −− 43
# Labs 1 1 1

Mean −− −− 166.8 167.8 −− −−
SD
CV
1 −−
−−
−−
−−
2 5.70
3.4
6.36
3.8
3 −−
−−
−−
−−
# Points −− −− 13 16 −− −−
# Labs 1 1

Mean −− 122.5 −− 180.5 −− 220.3
SD
CV
1 −−
−−
3.35
2.7
2 −−
−−
4.24
2.3
3 −−
−−
5.04
2.3
# Points −− 393 −− 389 −− 384
# Labs 1 1 1

Mean 119.0 123.1 166.8 175.2 207.0 209.7
SD
CV
1 5.64
4.7
5.95
4.8
2 6.38
3.8
9.45
5.4
3 8.38
4.0
11.74
5.6
# Points 387 12845 302 9171 146 11854
# Labs 16 55 14 47 5 43
IgG FIA mg/dL

Mean −− 579.9 −− 816.0 −− 937.7
SD
CV
1 −−
−−
15.25
2.6
2 −−
−−
26.73
3.3
3 −−
−−
28.05
3.0
# Points −− 84 −− 84 −− 84
# Labs 1 1 1

Mean −− 579.9 −− 816.0 −− 937.7
SD
CV
1 −−
−−
15.25
2.6
2 −−
−−
26.73
3.3
3 −−
−−
28.05
3.0
# Points −− 84 −− 84 −− 84
# Labs 1 1 1
IgG Immunonephelometric, end point mg/dL

Mean −− −− −− −− 993.4 970.8
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 25.66
2.6
36.74
3.8
# Points −− −− −− −− 86 815
# Labs 2 2
IgG Immunonephelometric, end point mg/dL

Mean −− −− −− −− 993.4 970.8
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 25.66
2.6
36.74
3.8
# Points −− −− −− −− 86 815
# Labs 2 2
IgG Immunonephelometric, fixed time, kinetic mg/dL

Mean −− 616.9 −− 879.9 −− 1014
SD
CV
1 −−
−−
11.34
1.8
2 −−
−−
13.73
1.6
3 −−
−−
15.70
1.5
# Points −− 589 −− 926 −− 508
# Labs 1 1 1

Mean 635.7 1393 882.3 881.2 1062 2855
SD
CV
1 21.75
3.4
6784
487.0
2 30.19
3.4
37.29
4.2
3 42.02
4.0
13339
467.3
# Points 92 5028 31 2480 43 3901
# Labs 2 9 1 6 2 8

Mean 635.7 1312 882.3 880.9 1062 2643
SD
CV
1 21.75
3.4
6423
489.7
2
30.19
3.4
32.62
3.7
3 42.02
4.0
12561
475.3
# Points 92 5617 31 3406 43 4409
# Labs 2 10 1 7 2 9
IgG Immunoturbidimetric mg/dL

Mean 608.1 600.0 894.6 884.1 −− 1013
SD
CV
1 15.76
2.6
16.82
2.8
2 22.39
2.5
29.76
3.4
3 −−
−−
26.18
2.6
# Points 189 1541 187 1086 −− 552
# Labs 9 15 9 14 4

Mean 581.0 583.5 851.4 829.0 964.2 957.4
SD
CV
1 12.34
2.1
16.40
2.8
2 13.94
1.6
24.97
3.0
3 20.17
2.1
29.98
3.1
# Points 113 5396 24 3262 89 5277
# Labs 4 14 1 9 3 12

Mean −− 594.0 −− −− −− 965.1
SD
CV
1 −−
−−
7.43
1.3
2 −−
−−
−−
−−
3 −−
−−
15.64
1.6
# Points −− 103 −− −− −− 103
# Labs 1 1

Mean −− −− −− 868.1 −− 999.3
SD
CV
1 −−
−−
−−
−−
2 −−
−−
39.28
4.5
3 −−
−−
45.89
4.6
# Points −− −− −− 41 −− 41
# Labs 1 1

Mean −− 628.8 −− −− −− −−
SD
CV
1 −−
−−
8.03
1.3
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 65 −− −− −− −−
# Labs 1
IgG Immunoturbidimetric mg/dL

Mean 619.8 605.2 872.8 868.1 1020 1000
SD
CV
1 20.27
3.3
18.93
3.1
2 30.41
3.5
20.97
2.4
3 17.14
1.7
26.33
2.6
# Points 104 3068 59 1087 45 3399
# Labs 4 10 2 6 2 9

Mean −− 622.1 −− 881.4 −− 1013
SD
CV
1 −−
−−
12.18
2.0
2 −−
−−
13.65
1.5
3 −−
−−
15.15
1.5
# Points −− 1149 −− 1134 −− 1137
# Labs 6 6 6

Mean −− −− −− 860.8 −− 994.9
SD
CV
1 −−
−−
−−
−−
2 −−
−−
18.51
2.2
3 −−
−−
19.78
2.0
# Points −− −− −− 270 −− 269
# Labs 1 1

Mean −− 599.3 −− 863.9 −− 1005
SD
CV
1 −−
−−
17.47
2.9
2 −−
−−
23.92
2.8
3 −−
−−
28.02
2.8
# Points −− 1846 −− 1381 −− 1813
# Labs 5 4 5

Mean 614.1 610.2 876.9 891.2 1070 1045
SD
CV
1 16.05
2.6
15.38
2.5
2 88.60
10.1
50.21
5.6
3 76.21
7.1
62.37
6.0
# Points 32 866 65 1158 60 1208
# Labs 3 5 4 6 2 4
The Binding Site

Mean −− 579.9 −− 825.7 −− 949.0
SD
CV
1 −−
−−
10.54
1.8
2 −−
−−
16.09
1.9
3 −−
−−
20.17
2.1
# Points −− 39 −− 39 −− 39
# Labs 1 1 1

Mean −− 631.4 −− 913.8 −− 1054
SD
CV
1 −−
−−
15.09
2.4
2 −−
−−
20.97
2.3
3 −−
−−
24.84
2.4
# Points −− 388 −− 389 −− 384
# Labs 1 1 1

Mean 604.3 598.1 884.2 862.0 1010 991.2
SD
CV
1 21.74
3.6
21.41
3.6
2 46.14
5.2
38.18
4.4
3 64.28
6.4
43.44
4.4
# Points 438 14461 335 9847 194 14222
# Labs 20 59 16 49 7 45
IgM FIA mg/dL

Mean −− 49.54 −− 68.85 −− 81.31
SD
CV
1 −−
−−
3.05
6.2
2 −−
−−
3.98
5.8
3 −−
−−
3.69
4.5
# Points −− 84 −− 84 −− 84
# Labs 1 1 1

Mean −− 49.54 −− 68.85 −− 81.31
SD
CV
1 −−
−−
3.05
6.2
2 −−
−−
3.98
5.8
3 −−
−−
3.69
4.5
# Points −− 84 −− 84 −− 84
# Labs 1 1 1
IgM Immunonephelometric, end point mg/dL

Mean −− −− −− −− 81.48 83.89
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 2.45
3.0
4.38
5.2
# Points −− −− −− −− 84 811
# Labs 2 2

Mean −− −− −− −− 81.48 83.89
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 2.45
3.0
4.38
5.2
# Points −− −− −− −− 84 811
# Labs 2 2
IgM Immunonephelometric, fixed time, kinetic mg/dL

Mean −− 49.87 −− 68.67 −− 81.94
SD
CV
1 −−
−−
2.90
5.8
2 −−
−−
2.21
3.2
3 −−
−−
1.99
2.4
# Points −− 586 −− 915 −− 507
# Labs 1 1 1

Mean 61.09 59.10 86.62 84.47 112.5 109.1
SD
CV
1 2.15
3.5
2.73
4.6
2 2.92
3.4
3.44
4.1
3 5.47
4.9
6.26
5.7
# Points 90 4947 31 2435 44 3826
# Labs 2 9 1 5 2 8

Mean 61.09 58.12 86.62 80.15 112.5 105.9
SD
CV
1 2.15
3.5
3.95
6.8
2
2.92
3.4
7.71
9.6
3 5.47
4.9
10.56
10.0
# Points 90 5533 31 3350 44 4333
# Labs 2 10 1 6 2 9
IgM Immunonephelometric, kinetic mg/dL

Mean 53.60 51.98 75.70 73.34 −− −−
SD
CV
1 2.90
5.4
3.26
6.3
2 3.10
4.1
3.41
4.6
3 −−
−−
−−
−−
# Points 83 978 87 991 −− −−
# Labs 1 1 1 1

Mean 53.60 51.98 75.70 73.34 −− −−
SD
CV
1 2.90
5.4
3.26
6.3
2 3.10
4.1
3.41
4.6
3 −−
−−
−−
−−
# Points 83 978 87 991 −− −−
# Labs 1 1 1 1
IgM Immunoturbidimetric mg/dL

Mean 54.52 53.96 75.52 75.53 −− 89.98
SD
CV
1 3.88
7.1
3.63
6.7
2 4.62
6.1
4.56
6.0
3 −−
−−
3.53
3.9
# Points 188 1432 188 1048 −− 402
# Labs 9 13 9 14 3

Mean 52.28 51.12 71.25 70.53 84.02 83.63
SD
CV
1 3.33
6.4
2.75
5.4
2 1.97
2.8
2.84
4.0
3 4.43
5.3
3.38
4.0
# Points 122 5469 24 3187 92 5211
# Labs 4 14 1 9 3 12

Mean −− 51.52 −− −− −− 83.78
SD
CV
1 −−
−−
2.62
5.1
2 −−
−−
−−
−−
3 −−
−−
3.02
3.6
# Points −− 108 −− −− −− 107
# Labs 1 1

Mean −− 51.20 −− −− −− −−
SD
CV
1 −−
−−
3.22
6.3
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 70 −− −− −− −−
# Labs 1

Mean 52.25 51.66 73.47 73.50 −− 87.67
SD
CV
1 1.88
3.6
2.76
5.3
2 1.96
2.7
4.09
5.6
3 −−
−−
3.35
3.8
# Points 57 2156 57 1028 −− 2333
# Labs 2 8 2 6 7

Mean −− 54.84 −− 76.25 −− 91.00
SD
CV
1 −−
−−
3.03
5.5
2 −−
−−
2.96
3.9
3 −−
−−
3.34
3.7
# Points −− 1156 −− 1198 −− 1206
# Labs 6 6 6

Mean −− −− −− 72.72 −− 87.31
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.19
3.0
3 −−
−−
2.20
2.5
# Points −− −− −− 279 −− 278
# Labs 1 1

Mean −− 52.15 −− 75.74 −− 91.11
SD
CV
1 −−
−−
2.93
5.6
2 −−
−−
3.07
4.1
3 −−
−−
3.51
3.8
# Points −− 1793 −− 1358 −− 1775
# Labs 5 4 5

Mean 52.99 53.14 75.65 76.08 91.25 91.31
SD
CV
1 1.90
3.6
2.15
4.0
2 4.96
6.6
3.58
4.7
3 5.66
6.2
4.61
5.0
# Points 34 862 62 1034 56 1067
# Labs 3 5 4 6 2 4
The Binding Site

Mean −− 58.27 −− 76.98 −− 87.71
SD
CV
1 −−
−−
3.55
6.1
2 −−
−−
3.49
4.5
3 −−
−−
3.74
4.3
# Points −− 36 −− 36 −− 35
# Labs 1 1 1

Mean −− −− 72.50 72.20 −− −−
SD
CV
1 −−
−−
−−
−−
2 5.03
6.9
4.61
6.4
3 −−
−−
−−
−−
# Points −− −− 10 12 −− −−
# Labs 1 1

Mean −− 64.88 −− 90.76 −− 108.8
SD
CV
1 −−
−−
2.90
4.5
2 −−
−−
3.28
3.6
3 −−
−−
3.53
3.2
# Points −− 400 −− 399 −− 391
# Labs 1 1 1

Mean 53.38 52.52 74.81 74.38 86.76 87.80
SD
CV
1 3.51
6.6
3.82
7.3
2 4.42
5.9
5.35
7.2
3 6.04
7.0
6.05
6.9
# Points 401 13482 341 9579 148 12805
# Labs 18 55 17 49 5 41
Iron AAS (Atomic Absorption Spectroscopy) µg/dL

Mean −− 78.05 −− −− −− 244.8
SD
CV
1 −−
−−
0.699
0.9
2 −−
−−
−−
−−
3 −−
−−
5.22
2.1
# Points −− 22 −− −− −− 22
# Labs 1 1

Mean −− 72.27 −− 157.7 −− 230.1
SD
CV
1 −−
−−
0.740
1.0
2 −−
−−
1.26
0.8
3 −−
−−
1.21
0.5
# Points −− 248 −− 244 −− 233
# Labs 1 1 1

Mean −− 70.38 −− 153.9 −− 222.1
SD
CV
1 −−
−−
1.48
2.1
2 −−
−−
1.90
1.2
3 −−
−−
2.76
1.2
# Points −− 444 −− 9 −− 419
# Labs 3 1 2

Mean −− 71.27 −− 158.3 −− 227.9
SD
CV
1 −−
−−
2.03
2.8
2 −−
−−
2.91
1.8
3 −−
−−
11.91
5.2
# Points −− 754 −− 293 −− 714
# Labs 6 3 5
Iron Bathophenanthroline−deproteinization µg/dL

Mean −− −− −− 158.3 −− 229.8
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.31
1.5
3 −−
−−
3.09
1.3
# Points −− −− −− 588 −− 592
# Labs 3 3

Mean −− 76.81 −− −− −− 244.3
SD
CV
1 −−
−−
1.04
1.4
2 −−
−−
−−
−−
3 −−
−−
2.26
0.9
# Points −− 349 −− −− −− 346
# Labs 1 1
Method Group • Bathophenanthroline−deproteinization

Mean −− 76.81 −− 158.3 −− 235.1
SD
CV
1 −−
−−
1.04
1.4
2 −−
−−
2.31
1.5
3 −−
−−
7.55
3.2
# Points −− 349 −− 588 −− 938
# Labs 1 3 4
Iron Bathophenanthroline−no deproteinization µg/dL

Mean −− 70.86 −− −− −− 231.1
SD
CV
1 −−
−−
2.52
3.6
2 −−
−−
−−
−−
3 −−
−−
8.72
3.8
# Points −− 214 −− −− −− 193
# Labs 1 1
Iron Bathophenanthroline−no deproteinization µg/dL

Mean −− 77.46 −− −− −− 244.4
SD
CV
1 −−
−−
2.35
3.0
2 −−
−−
−−
−−
3 −−
−−
5.17
2.1
# Points −− 395 −− −− −− 394
# Labs 2 2
Siemens ADVIA Chemistry Systems • Wako

Mean −− 76.15 −− −− −− 247.4
SD
CV
1 −−
−−
1.63
2.1
2 −−
−−
−−
−−
3 −−
−−
4.15
1.7
# Points −− 1206 −− −− −− 1205
# Labs 2 2
Method Group • Bathophenanthroline−no deproteinization

Mean −− 75.81 −− −− −− 245.0
SD
CV
1 −−
−−
2.70
3.6
2 −−
−−
−−
−−
3 −−
−−
7.11
2.9
# Points −− 1815 −− −− −− 1792
# Labs 5 5
Iron Chromazurol Dye µg/dL

Mean −− 66.68 −− −− −− 282.3
SD
CV
1 −−
−−
6.07
9.1
2 −−
−−
−−
−−
3 −−
−−
35.31
12.5
# Points −− 273 −− −− −− 292
# Labs 1 1
Method Group • Chromazurol Dye

Mean −− 66.68 −− −− −− 282.3
SD
CV
1 −−
−−
6.07
9.1
2 −−
−−
−−
−−
3 −−
−−
35.31
12.5
# Points −− 273 −− −− −− 292
# Labs 1 1
Iron Ferene µg/dL

Mean 77.07 76.23 166.3 162.4 242.8 237.2
SD
CV
1 3.47
4.5
3.30
4.3
2 6.05
3.6
6.08
3.7
3 9.20
3.8
8.13
3.4
# Points 575 41642 349 23737 356 40722
# Labs 18 151 14 98 13 122
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH Iron2, REF 04T02

Mean 76.34 76.17 165.5 165.1 246.8 244.9
SD
CV
1 2.98
3.9
2.03
2.7
2
5.53
3.3
3.94
2.4
3 1.59
0.6
3.88
1.6
# Points 482 2174 447 1867 65 453
# Labs 19 23 18 21 2 5
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCHITECT Iron 6K95, Cal Lot 11100Y700+
Mean −− 75.01 −− −− −− 235.3
SD
CV
1 −−
−−
1.83
2.4
−−
−−
2 −−
−−
3 −−
−−
3.61
1.5
# Points −− 463 −− −− −− 525
# Labs 1 1
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c Iron, REF 08P39

Mean −− 76.10 −− 163.9 −− −−
SD
CV
1 −−
−−
0.891
1.2
2 −−
−−
1.16
0.7
3 −−
−−
−−
−−
# Points −− 19 −− 19 −− −−
# Labs 2 2
Iron Ferene µg/dL

Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c Iron2, REF 04T98
Mean 75.06 75.74 160.9 163.3 237.7 240.1
SD
CV
1 1.93
2.6
2.68
3.5
2 3.91
2.4
8.09
5.0
3 6.61
2.8
5.45
2.3
# Points 600 3108 362 1412 341 1801
# Labs 23 34 17 26 12 20

Mean −− 70.61 −− 152.4 −− 226.8
SD
CV
1 −−
−−
3.30
4.7
2 −−
−−
2.83
1.9
3 −−
−−
7.34
3.2
# Points −− 1034 −− 699 −− 990
# Labs 6 1 6

Mean −− −− −− 154.2 −− 225.9
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.61
1.7
3 −−
−−
3.47
1.5
# Points −− −− −− 363 −− 360
# Labs 1 1

Mean −− 74.63 −− 163.7 −− 235.6
SD
CV
1 −−
−−
6.49
8.7
2 −−
−−
15.61
9.5
3 −−
−−
21.19
9.0
# Points −− 51 −− 35 −− 41
# Labs 2 1 2

Mean −− 73.19 −− 158.7 −− 230.9
SD
CV
1 −−
−−
1.18
1.6
2 −−
−−
1.75
1.1
3 −−
−−
2.32
1.0
# Points −− 596 −− 934 −− 496
# Labs 1 1 1
Mean −− −− −− 140.0 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
3.23
2.3
3 −−
−−
−−
−−
# Points −− −− −− 3 −− −−
# Labs 1

Mean −− 84.74 −− 172.0 −− 246.3
SD
CV
1 −−
−−
8.49
10.0
2 −−
−−
11.57
6.7
3 −−
−−
16.53
6.7
# Points −− 80 −− 106 −− 108
# Labs 1 1 1
Siemens ADVIA Chemistry Systems • Sentinel MULTIGENT Iron REF 6K95

Mean −− 73.94 −− 159.9 −− 233.2
SD
CV
1 −−
−−
4.78
6.5
−−
−−
2 6.86
4.3
3 −−
−−
10.09
4.3
# Points −− 415 −− 414 −− 415
# Labs 1 1 1

Mean −− 71.76 −− 151.7 −− 220.5
SD
CV
1 −−
−−
3.30
4.6
2 −−
−−
5.98
3.9
3 −−
−−
7.02
3.2
# Points −− 321 −− 374 −− 327
# Labs 1 1 1

Mean −− 70.15 −− 153.0 −− 220.3
SD
CV
1 −−
−−
1.10
1.6
2
−−
−−
2.38
1.6
3 −−
−−
1.84
0.8
# Points −− 69 −− 33 −− 78
# Labs 1 1 1
Iron Ferene µg/dL

Mean 68.70 69.92 149.6 152.0 217.0 220.3
SD
CV
1 1.38
2.0
1.66
2.4
2 2.24
1.5
3.19
2.1
3 2.87
1.3
4.50
2.0
# Points 674 38434 136 7574 616 33495
# Labs 22 120 5 36 20 99
Siemens Dimension Series • Siemens Dimension IRON, DF85

Mean 69.41 69.75 −− −− 218.0 221.5
SD
CV
1 0.756
1.1
1.77
2.5
2 −−
−−
−−
−−
3 1.09
0.5
3.47
1.6
# Points 32 2189 −− −− 32 1702
# Labs 1 4 1 4

Mean 71.10 71.34 151.5 153.9 220.1 223.4
SD
CV
1 2.32
3.3
1.78
2.5
2 2.88
1.9
2.54
1.6
3 4.15
1.9
3.62
1.6
# Points 2128 161K 480 44020 1919 153K
# Labs 60 349 18 103 60 331

Mean −− −− 15.95 15.96 −− −−
SD
CV
1 −−
−−
−−
−−
2 0.345
2.2
0.344
2.2
3 −−
−−
−−
−−
# Points −− −− 20 25 −− −−
# Labs 1 1
Method Group • Ferene

Mean 72.58 72.03 158.1 156.7 224.3 225.6
SD
CV
1 3.76
5.2
2.98
4.1
2 17.07
10.8
6.50
4.2
3 10.50
4.7
7.60
3.4
# Points 4491 252K 1794 81616 3329 235K
# Labs 143 697 73 296 108 596
Iron Ferrozine−deproteinization µg/dL

Mean −− 69.74 −− 135.0 −− 227.2
SD
CV
1 −−
−−
3.29
4.7
2 −−
−−
8.16
6.0
3 −−
−−
4.05
1.8
# Points −− 414 −− 413 −− 279
# Labs 5 3 1
ERBA XL−640
Mean −− 75.92 −− 157.9 −− −−
SD
CV
1 −−
−−
7.75
10.2
2 −−
−−
3.92
2.5
3 −−
−−
−−
−−
# Points −− 60 −− 60 −− −−
# Labs 1 1

Mean −− 74.00 −− −− −− 231.0
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− 1 −− −− −− 1
# Labs 1 1
Roche cobas c 303/503 • Roche IRON2, REF 08057931

Mean 73.17 73.52 −− −− −− −−
SD
CV
1 1.49
2.0
1.55
2.1
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points 110 171 −− −− −− −−
# Labs 2 2

Mean −− 70.90 −− 155.3 −− 226.3
SD
CV
1 −−
−−
1.59
2.2
2 −−
−−
2.55
1.6
3 −−
−−
3.70
1.6
# Points −− 3084 −− 3108 −− 3077
# Labs 4 5 4
Iron Ferrozine−deproteinization µg/dL

Mean −− 71.39 −− 155.2 −− 227.8
SD
CV
1 −−
−−
1.57
2.2
2 −−
−−
1.83
1.2
3 −−
−−
3.26
1.4
# Points −− 1543 −− 328 −− 1478
# Labs 4 2 3

Mean −− 76.09 −− 163.3 −− 269.8
SD
CV
1 −−
−−
4.11
5.4
2 −−
−−
7.47
4.6
3 −−
−−
9.87
3.7
# Points −− 85 −− 83 −− 85
# Labs 1 1 1

Mean −− 77.11 −− 165.1 −− 268.7
SD
CV
1 −−
−−
4.22
5.5
2 −−
−−
6.87
4.2
3 −−
−−
9.78
3.6
# Points −− 277 −− 274 −− 275
# Labs 1 1 1

Mean −− 75.86 −− 163.8 −− 267.5
SD
CV
1 −−
−−
4.72
6.2
2 −−
−−
6.65
4.1
3 −−
−−
7.97
3.0
# Points −− 123 −− 124 −− 124
# Labs 1 1 1

Mean −− 70.05 −− 158.5 −− 257.7
SD
CV
1 −−
−−
5.85
8.4
2 −−
−−
6.50
4.1
3 −−
−−
10.02
3.9
# Points −− 167 −− 170 −− 164
# Labs 1 1 1
Method Group • Ferrozine−deproteinization

Mean 73.17 71.52 −− 154.6 −− 231.4
SD
CV
1 1.49
2.0
2.97
4.2
2 −−
−−
7.99
5.2
3 −−
−−
13.56
5.9
# Points 110 5925 −− 4560 −− 5483
# Labs 2 21 15 13
Iron Ferrozine−no deproteinization µg/dL

Abbott ARCHITECT/Alinity (c, i, ci models) • Shinotest
Mean 73.41 71.85 156.4 158.5 231.7 231.0
SD
CV
1 2.07
2.8
1.83
2.5
2 2.23
1.4
2.22
1.4
3 3.35
1.4
2.59
1.1
# Points 21 372 21 411 21 409
# Labs 1 1 1 1 1 1

Mean −− 73.91 158.2 162.8 231.6 240.0
SD
CV
1 −−
−−
5.32
7.2
2 2.57
1.6
8.30
5.1
3 1.68
0.7
12.93
5.4
# Points −− 2046 31 2424 31 2569
# Labs 5 1 6 1 6

Mean 72.00 72.33 −− 155.0 235.1 237.0
SD
CV
1 0.816
1.1
2.47
3.4
2 −−
−−
4.37
2.8
3 1.90
0.8
5.77
2.4
# Points 34 6978 −− 1785 34 6338
# Labs 1 24 6 1 22

Mean −− 74.15 −− 154.9 −− 243.1
SD
CV
1 −−
−−
3.65
4.9
2 −−
−−
5.80
3.7
3 −−
−−
4.66
1.9
# Points −− 2589 −− 2054 −− 717
# Labs 6 4 4
Iron Ferrozine−no deproteinization µg/dL

Mean 73.62 73.52 160.5 158.5 231.5 231.0
SD
CV
1 2.13
2.9
2.19
3.0
2 4.66
2.9
3.57
2.3
3 3.54
1.5
4.57
2.0
# Points 1342 52742 125 14950 1282 52458
# Labs 30 121 4 46 28 119

Mean 72.81 73.19 158.2 159.2 232.5 231.7
SD
CV
1 1.11
1.5
1.35
1.8
2 2.65
1.7
2.29
1.4
3 3.23
1.4
3.42
1.5
# Points 94 5566 72 4568 52 5347
# Labs 3 18 2 12 2 17
Roche cobas c 303/503 • Roche IRON2, REF 08057931

Mean 73.27 73.17 160.1 159.2 231.4 231.2
SD
CV
1 1.03
1.4
1.56
2.1
2 1.46
0.9
2.14
1.3
3 1.33
0.6
3.84
1.7
# Points 161 6571 46 1847 147 6663
# Labs 6 24 2 7 5 24

Mean 73.18 72.71 157.5 157.6 −− 230.8
SD
CV
1 1.23
1.7
1.52
2.1
2 2.29
1.5
2.84
1.8
3 −−
−−
3.93
1.7
# Points 88 943 90 1315 −− 306
# Labs 1 2 1 2 2

Mean 70.00 72.70 −− −− 223.0 229.0
SD
CV
1 6.00
8.6
2.99
4.1
2 −−
−−
−−
−−
3 6.00
2.7
4.26
1.9
# Points 25 638 −− −− 23 608
# Labs 1 3 1 3
Mean −− −− −− 135.5 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.19
0.9
3 −−
−−
−−
−−
# Points −− −− −− 2 −− −−
# Labs 1

Mean 71.22 71.66 156.8 156.0 225.8 227.9
SD
CV
1 1.41
2.0
1.85
2.6
2 1.21
0.8
3.42
2.2
3 3.55
1.6
5.16
2.3
# Points 55 4865 53 3208 55 4504
# Labs 3 20 2 16 3 18

Mean 72.66 71.87 156.7 155.5 229.5 228.0
SD
CV
1 1.58
2.2
2.04
2.8
2 2.32
1.5
3.10
2.0
3 3.84
1.7
4.98
2.2
# Points 508 24538 394 13911 178 17379
# Labs 17 73 13 56 8 55

Mean −− 81.59 −− 177.2 −− 259.4
SD
CV
1 −−
−−
1.13
1.4
2 −−
−−
2.67
1.5
3 −−
−−
2.62
1.0
# Points −− 231 −− 230 −− 235
# Labs 3 3 3
Method Group • Ferrozine−no deproteinization

Mean 73.22 72.97 157.8 157.6 231.1 231.1
SD
CV
1 2.05
2.8
2.40
3.3
2 3.09
2.0
4.56
2.9
3 3.76
1.6
5.92
2.6
# Points 2328 108K 832 46979 1823 97533
# Labs 63 300 26 162 50 274
Iron ICP−MS (Inductively Coupled Plasma−Mass Spectroscopy) µg/dL

Mean −− −− −− 155.5 −− 233.1
SD
CV
1 −−
−−
−−
−−
2 −−
−−
3.86
2.5
3 −−
−−
3.95
1.7
# Points −− −− −− 105 −− 105
# Labs 1 1
Method Group • ICP−MS (Inductively Coupled Plasma−Mass Spectroscopy)

Mean −− −− −− 155.5 −− 233.1
SD
CV
1 −−
−−
−−
−−
−−
−−
2 3.86
2.5
3 −−
−−
3.95
1.7
# Points −− −− −− 105 −− 105
# Labs 1 1
Iron Nitroso−PSAP µg/dL

Mean −− 72.14 −− −− −− −−
SD
CV
1 −−
−−
0.578
0.8
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 61 −− −− −− −−
# Labs 1
Method Group • Nitroso−PSAP

Mean −− 72.14 −− −− −− −−
SD
CV
1 −−
−−
0.578
0.8
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 61 −− −− −− −−
# Labs 1
Iron Pyridyl azo dye µg/dL

Mean −− 69.55 −− 161.8 −− 257.1
SD
CV
1 −−
−−
5.90
8.5
2 −−
−−
11.97
7.4
3 −−
−−
10.87
4.2
# Points −− 1095 −− 389 −− 689
# Labs 12 9 5

Mean −− −− −− −− −− 250.3
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
11.43
4.6
# Points −− −− −− −− −− 66
# Labs 1

Mean −− 62.34 158.7 160.1 −− 262.0
SD
CV
1 −−
−−
6.63
10.6
2 16.90
10.6
9.88
6.2
3 −−
−−
8.12
3.1
# Points −− 152 10 96 −− 99
# Labs 2 1 1 1

Mean −− 63.84 −− −− −− 274.8
SD
CV
1 −−
−−
2.99
4.7
2 −−
−−
−−
−−
3 −−
−−
6.28
2.3
# Points −− 54 −− −− −− 57
# Labs 1 1

Mean −− 65.83 −− 143.3 −− 253.9
SD
CV
1 −−
−−
3.95
6.0
2 −−
−−
10.94
7.6
3 −−
−−
13.39
5.3
# Points −− 222 −− 88 −− 306
# Labs 1 2 3

Mean −− 65.84 −− −− −− 259.3
SD
CV
1 −−
−−
3.51
5.3
2 −−
−−
−−
−−
3 −−
−−
8.86
3.4
# Points −− 142 −− −− −− 148
# Labs 1 1

Mean −− 69.26 −− −− −− 262.4
SD
CV
1 −−
−−
4.27
6.2
2 −−
−−
−−
−−
3 −−
−−
9.31
3.5
# Points −− 178 −− −− −− 174
# Labs 2 2

Mean −− 71.04 −− −− −− 256.8
SD
CV
1 −−
−−
6.42
9.0
2 −−
−−
−−
−−
3 −−
−−
13.88
5.4
# Points −− 198 −− −− −− 213
# Labs 2 2

Mean −− 68.25 −− −− −− 257.2
SD
CV
1 −−
−−
2.53
3.7
2 −−
−−
−−
−−
3 −−
−−
6.99
2.7
# Points −− 174 −− −− −− 173
# Labs 1 1

Mean −− 76.38 −− −− −− 261.3
SD
CV
1 −−
−−
14.64
19.2
2 −−
−−
−−
−−
3 −−
−−
8.74
3.3
# Points −− 269 −− −− −− 229
# Labs 2 2

Mean −− 71.58 −− −− −− 252.0
SD
CV
1 −−
−−
5.26
7.4
2 −−
−−
−−
−−
3 −−
−−
11.29
4.5
# Points −− 311 −− −− −− 297
# Labs 2 2

Mean −− 69.89 −− −− −− 251.7
SD
CV
1 −−
−−
5.56
7.9
2 −−
−−
−−
−−
3 −−
−−
8.47
3.4
# Points −− 284 −− −− −− 277
# Labs 4 4

Mean −− 66.78 −− 160.9 −− 253.1
SD
CV
1 −−
−−
6.11
9.1
2 −−
−−
7.54
4.7
3 −−
−−
12.84
5.1
# Points −− 1971 −− 388 −− 1525
# Labs 16 6 15

Mean −− 67.49 −− 150.6 −− 250.0
SD
CV
1 −−
−−
6.23
9.2
2 −−
−−
12.40
8.2
3 −−
−−
15.94
6.4
# Points −− 1457 −− 626 −− 1776
# Labs 17 9 19

Mean −− 65.88 −− 160.2 −− 250.0
SD
CV
1 −−
−−
7.06
10.7
2 −−
−−
8.80
5.5
3 −−
−−
15.25
6.1
# Points −− 2718 −− 1396 −− 2559
# Labs 29 18 28

Mean −− 64.37 −− 160.7 −− 254.0
SD
CV
1 −−
−−
6.71
10.4
2 −−
−−
10.92
6.8
3 −−
−−
15.57
6.1
# Points −− 7116 −− 4316 −− 7366
# Labs 51 25 50

Mean −− 67.90 −− 161.7 −− 253.5
SD
CV
1 −−
−−
6.25
9.2
2 −−
−−
9.14
5.7
3 −−
−−
13.92
5.5
# Points −− 6596 −− 3306 −− 6864
# Labs 41 24 42

Mean −− 67.54 −− 161.0 −− 253.9
SD
CV
1 −−
−−
6.74
10.0
2 −−
−−
11.17
6.9
3 −−
−−
13.86
5.5
# Points −− 2921 −− 1474 −− 2902
# Labs 25 12 23

Mean 69.68 67.27 159.7 160.0 −− 254.7
SD
CV
1 5.41
7.8
6.44
9.6
2 5.56
3.5
8.56
5.4
3 −−
−−
14.12
5.5
# Points 46 2899 34 851 −− 3150
# Labs 2 36 2 12 29

Mean 63.03 64.94 161.3 159.7 249.7 252.8
SD
CV
1 6.87
10.9
5.83
9.0
2 10.62
6.6
10.66
6.7
3 14.86
6.0
14.68
5.8
# Points 37 2503 17 1095 35 2569
# Labs 2 23 1 11 2 20

Mean 72.79 69.03 −− 163.9 258.7 254.5
SD
CV
1 4.20
5.8
5.63
8.2
2 −−
−−
7.94
4.8
3 14.28
5.5
13.04
5.1
# Points 39 1416 −− 499 38 1187
# Labs 4 23 10 4 19

Mean 67.61 69.11 160.1 162.3 260.9 255.5
SD
CV
1 5.88
8.7
6.06
8.8
2 6.51
4.1
9.55
5.9
3 7.78
3.0
13.01
5.1
# Points 115 2286 57 1382 133 2011
# Labs 7 24 4 13 6 19

Mean 72.94 73.02 168.4 168.2 261.0 263.2
SD
CV
1 7.31
10.0
6.74
9.2
2 10.61
6.3
10.57
6.3
3 14.12
5.4
12.81
4.9
# Points 450 2379 254 713 357 2168
# Labs 19 26 11 12 16 23

Mean 72.81 73.99 167.0 167.0 255.1 256.8
SD
CV
1 5.37
7.4
6.13
8.3
2 6.00
3.6
6.00
3.6
3 12.37
4.8
12.98
5.1
# Points 120 147 21 21 122 136
# Labs 7 7 1 1 7 7

Mean −− 61.30 −− −− −− 262.4
SD
CV
1 −−
−−
5.44
8.9
2 −−
−−
−−
−−
3 −−
−−
6.13
2.3
# Points −− 23 −− −− −− 22
# Labs 1 1

Mean −− 52.32 −− −− −− 251.9
SD
CV
1 −−
−−
5.12
9.8
2 −−
−−
−−
−−
3 −−
−−
9.14
3.6
# Points −− 72 −− −− −− 71
# Labs 1 1

Mean −− 60.04 −− −− −− 253.7
SD
CV
1 −−
−−
5.67
9.4
2 −−
−−
−−
−−
3 −−
−−
16.58
6.5
# Points −− 101 −− −− −− 117
# Labs 1 1

Mean −− 63.55 −− −− −− 256.3
SD
CV
1 −−
−−
5.73
9.0
2 −−
−−
−−
−−
3 −−
−−
11.03
4.3
# Points −− 138 −− −− −− 112
# Labs 1 1

Mean −− 63.91 −− −− −− 250.1
SD
CV
1 −−
−−
5.24
8.2
2 −−
−−
−−
−−
3 −−
−−
10.03
4.0
# Points −− 123 −− −− −− 122
# Labs 2 2
Method Group • Pyridyl azo dye

Mean 71.51 67.24 165.8 160.9 259.2 254.0
SD
CV
1 7.11
9.9
6.94
10.3
2 10.44
6.3
10.53
6.5
3 13.20
5.1
14.44
5.7
# Points 807 37461 393 16638 685 36767
# Labs 41 354 20 165 35 327
Iron Pyridyl or dipyridyl µg/dL

Mean −− 63.96 −− 157.4 −− 249.3
SD
CV
1 −−
−−
5.32
8.3
2 −−
−−
8.08
5.1
3 −−
−−
11.82
4.7
# Points −− 1100 −− 1123 −− 1099
# Labs 5 5 5

Mean −− 65.63 −− 158.5 −− 254.9
SD
CV
1 −−
−−
5.24
8.0
2 −−
−−
7.77
4.9
3 −−
−−
10.10
4.0
# Points −− 323 −− 346 −− 350
# Labs 4 4 4

Mean −− 68.03 −− 162.7 −− 252.3
SD
CV
1 −−
−−
4.13
6.1
2 −−
−−
5.83
3.6
3 −−
−−
9.93
3.9
# Points −− 180 −− 186 −− 186
# Labs 5 5 5
Method Group • Pyridyl or dipyridyl

Mean −− 64.76 −− 158.3 −− 250.9
SD
CV
1 −−
−−
5.35
8.3
2 −−
−−
7.96
5.0
3 −−
−−
11.50
4.6
# Points −− 1603 −− 1655 −− 1635
# Labs 14 14 14
Iron TPTZ−deproteinization µg/dL

Mean 78.00 71.94 157.9 157.4 236.2 234.3
SD
CV
1 2.00
2.6
2.22
3.1
2 2.41
1.5
4.00
2.5
3 8.58
3.6
7.16
3.1
# Points 22 1276 85 1150 107 2526
# Labs 1 4 2 3 3 7
Method Group • TPTZ−deproteinization

Mean 78.00 71.94 157.9 157.4 236.2 234.3
SD
CV
1 2.00
2.6
2.22
3.1
2 2.41
1.5
4.00
2.5
3 8.58
3.6
7.16
3.1
# Points 22 1276 85 1150 107 2526
# Labs 1 4 2 3 3 7
Iron TPTZ−no deproteinization µg/dL

Abbott ARCHITECT/Alinity (c, i, ci models) • Kanto Kagaku
Mean −− −− −− 158.6 −− 231.6
SD
CV
1 −−
−−
−−
−−
2 −−
−−
6.72
4.2
3 −−
−−
7.60
3.3
# Points −− −− −− 576 −− 572
# Labs 2 2

Mean 75.48 74.69 168.2 163.8 244.8 244.4
SD
CV
1 4.23
5.6
4.29
5.7
2 6.89
4.1
7.90
4.8
3 10.98
4.5
10.96
4.5
# Points 1311 55678 999 36733 728 52789
# Labs 42 160 29 105 23 144

Mean −− 72.00 −− 152.9 −− 241.0
SD
CV
1 −−
−−
0.893
1.2
2 −−
−−
2.93
1.9
3 −−
−−
4.57
1.9
# Points −− 11 −− 23 −− 12
# Labs 2 2 2
Beckman Coulter AU Series • Kanto Kagaku

Mean −− −− 159.3 160.1 231.5 233.5
SD
CV
1 −−
−−
−−
−−
2 0.838
0.5
5.42
3.4
3 0.335
0.1
7.09
3.0
# Points −− −− 5 726 4 727
# Labs 1 2 1 2
Dirui CS Series • Kanto Kagaku

Mean −− −− 163.8 161.1 235.4 232.5
SD
CV
1 −−
−−
−−
−−
2 4.20
2.6
4.17
2.6
3 4.10
1.7
4.40
1.9
# Points −− −− 44 224 42 224
# Labs 3 3 3 3
Mindray CL Series • Kanto Kagaku

Mean −− −− −− 165.1 −− 240.4
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.65
1.6
3 −−
−−
3.42
1.4
# Points −− −− −− 276 −− 276
# Labs 2 2
Method Group • TPTZ−no deproteinization

Mean 75.48 74.69 167.9 163.6 244.2 244.1
SD
CV
1 4.23
5.6
4.29
5.7
2 6.86
4.1
7.85
4.8
3 10.94
4.5
11.02
4.5
# Points 1311 55689 1048 38558 774 54600
# Labs 42 162 33 116 27 155
Lactic Acid Chemical oxidation mEq/L

Mean −− 0.068 −− 2.05 −− 0.595
SD
CV
1 −−
−−
0.219
320.6
2 −−
−−
0.029
1.4
3 −−
−−
1.92
322.7
# Points −− 187 −− 16 −− 185
# Labs 2 1 2

Mean −− 1.46 −− −− −− 5.70
SD
CV
1 −−
−−
0.049
3.3
2 −−
−−
−−
−−
3 −−
−−
0.072
1.3
# Points −− 30 −− −− −− 30
# Labs 1 1

Mean −− 1.37 −− 3.20 −− 5.79
SD
CV
1 −−
−−
0.024
1.7
2 −−
−−
0.043
1.3
3 −−
−−
0.073
1.3
# Points −− 84 −− 85 −− 85
# Labs 1 1 1

Mean −− 1.36 −− 3.20 −− 5.43
SD
CV
1 −−
−−
0.017
1.3
2 −−
−−
0.040
1.3
3 −−
−−
0.114
2.1
# Points −− 151 −− 57 −− 158
# Labs 2 1 2

Mean −− 0.001 −− −− −− 0.005
SD
CV
1 −−
−−
0.000
2.8
2 −−
−−
−−
−−
3 −−
−−
0.000
2.8
# Points −− 30 −− −− −− 29
# Labs 1 1

Mean −− 1.40 −− 3.30 −− 5.43
SD
CV
1 −−
−−
0.029
2.1
2 −−
−−
0.057
1.7
3 −−
−−
0.076
1.4
# Points −− 91 −− 96 −− 97
# Labs 1 1 1

Mean −− 1.38 −− 3.22 −− 5.42
SD
CV
1 −−
−−
0.024
1.7
2 −−
−−
0.045
1.4
3 −−
−−
0.066
1.2
# Points −− 111 −− 31 −− 157
# Labs 2 1 2

Mean −− 1.36 −− −− −− 5.39
SD
CV
1 −−
−−
0.028
2.1
2 −−
−−
−−
−−
3 −−
−−
0.380
7.1
# Points −− 17 −− −− −− 14
# Labs 1 1
Method Group • Chemical oxidation

Mean 0.171 0.603 −− 3.24 0.662 2.59
SD
CV
1 0.005
3.2
0.610
101.1
2 −−
−−
0.068
2.1
3 0.010
1.4
2.50
96.6
# Points 29 1203 −− 269 29 1260
# Labs 1 11 4 1 11
Lactic Acid Chemical oxidation mg/dL

Mean −− 0.615 −− 18.48 −− 5.36
SD
CV
1 −−
−−
1.97
320.6
2 −−
−−
0.265
1.4
3 −−
−−
17.30
322.7
# Points −− 187 −− 16 −− 185
# Labs 2 1 2
Lactic Acid Chemical oxidation mg/dL

Mean −− 13.18 −− −− −− 51.32
SD
CV
1 −−
−−
0.442
3.3
2 −−
−−
−−
−−
3 −−
−−
0.647
1.3
# Points −− 30 −− −− −− 30
# Labs 1 1

Mean −− 12.38 −− 28.84 −− 52.19
SD
CV
1 −−
−−
0.213
1.7
2 −−
−−
0.386
1.3
3 −−
−−
0.659
1.3
# Points −− 84 −− 85 −− 85
# Labs 1 1 1

Mean −− 12.27 −− 28.81 −− 48.88
SD
CV
1 −−
−−
0.155
1.3
2 −−
−−
0.365
1.3
3 −−
−−
1.03
2.1
# Points −− 151 −− 57 −− 158
# Labs 2 1 2

Mean −− 0.013 −− −− −− 0.049
SD
CV
1 −−
−−
0.000
2.8
2 −−
−−
−−
−−
3 −−
−−
0.001
2.8
# Points −− 30 −− −− −− 29
# Labs 1 1

Mean −− 12.63 −− 29.77 −− 48.92
SD
CV
1 −−
−−
0.259
2.1
2 −−
−−
0.516
1.7
3 −−
−−
0.684
1.4
# Points −− 91 −− 96 −− 97
# Labs 1 1 1

Mean −− 12.41 −− 29.04 −− 48.79
SD
CV
1 −−
−−
0.216
1.7
2 −−
−−
0.406
1.4
3 −−
−−
0.593
1.2
# Points −− 111 −− 31 −− 157
# Labs 2 1 2

Mean −− 12.25 −− −− −− 48.56
SD
CV
1 −−
−−
0.252
2.1
2 −−
−−
−−
−−
3 −−
−−
3.42
7.1
# Points −− 17 −− −− −− 14
# Labs 1 1
Method Group • Chemical oxidation

Mean 1.54 5.43 −− 29.19 5.97 23.34
SD
CV
1 0.049
3.2
5.49
101.1
2 −−
−−
0.614
2.1
3 0.086
1.4
22.56
96.6
# Points 29 1203 −− 269 29 1260
# Labs 1 11 4 1 11
Lactic Acid Electrode, direct mEq/L

Mean −− 1.41 −− −− −− 6.51
SD
CV
1 −−
−−
0.102
7.2
2 −−
−−
−−
−−
3 −−
−−
0.166
2.5
# Points −− 103 −− −− −− 103
# Labs 1 1
Method Group • Electrode, direct

Mean −− 1.41 −− −− −− 6.51
SD
CV
1 −−
−−
0.102
7.2
2 −−
−−
−−
−−
3 −−
−−
0.166
2.5
# Points −− 103 −− −− −− 103
# Labs 1 1
Lactic Acid Electrode, direct mg/dL

Mean −− 12.74 −− −− −− 58.68
SD
CV
1 −−
−−
0.921
7.2
2 −−
−−
−−
−−
3 −−
−−
1.49
2.5
# Points −− 103 −− −− −− 103
# Labs 1 1
Method Group • Electrode, direct

Mean −− 12.74 −− −− −− 58.68
SD
CV
1 −−
−−
0.921
7.2
2 −−
−−
−−
−−
3 −−
−−
1.49
2.5
# Points −− 103 −− −− −− 103
# Labs 1 1
Lactic Acid Enzymatic mEq/L

Mean 1.53 1.53 3.39 3.23 6.04 6.06
SD
CV
1 0.036
2.3
0.045
3.0
2 0.062
1.8
0.652
20.2
3 0.110
1.8
0.176
2.9
# Points 297 10460 90 4257 228 10345
# Labs 9 32 4 16 7 30
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH Lactic Acid, REF 9P18
Mean 1.56 1.53 3.45 3.37 6.19 6.08
SD
CV
1 0.049
3.2
0.048
3.2
2
0.050
1.4
0.081
2.4
3 0.112
1.8
0.183
3.0
# Points 96 14316 31 6036 95 13397
# Labs 3 38 1 21 3 35

Mean 1.42 1.40 3.20 3.19 5.54 5.47
SD
CV
1 0.045
3.1
0.114
8.1
2 0.111
3.5
0.120
3.8
3 0.155
2.8
0.439
8.0
# Points 338 16857 68 5553 354 16178
# Labs 10 52 4 24 12 48

Mean −− −− −− 2.87 −− 4.83
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.134
4.7
3 −−
−−
0.299
6.2
# Points −− −− −− 591 −− 590
# Labs 2 2

Mean −− −− 3.61 3.58 6.35 6.29
SD
CV
1 −−
−−
−−
−−
2 0.225
6.3
0.159
4.4
3 0.440
6.9
0.267
4.2
# Points −− −− 5 461 4 461
# Labs 1 2 1 2

Mean 1.45 1.52 −− 3.30 5.46 5.65
SD
CV
1 0.064
4.4
0.057
3.8
2 −−
−−
0.081
2.5
3 0.180
3.3
0.128
2.3
# Points 78 6503 −− 522 68 6518
# Labs 2 18 3 2 18
Beckman Coulter UniCel DxC Series • Beckman Coulter LACT, REF A95550
Mean −− 1.52 −− 3.26 −− 5.62
SD
CV
1 −−
−−
0.066
4.4
−−
−−
20.100
3.1
3 −−
−−
0.135
2.4
# Points −− 423 −− 335 −− 387
# Labs 3 2 3
Beckman Coulter UniCel DxC Series • Pointe Scientific, Inc. (MedTest Dx)
Mean −− 0.181 −− 0.371 −− 0.616
SD
CV
1 −−
−−
0.006
3.4
2
−−
−−
0.008
2.3
3 −−
−−
0.013
2.1
# Points −− 275 −− 277 −− 277
# Labs 2 2 2

Mean −− −− 3.19 3.39 6.31 6.04
SD
CV
1 −−
−−
−−
−−
2 0.027
0.8
0.223
6.6
3 0.053
0.8
0.217
3.6
# Points −− −− 5 59 4 58
# Labs 1 2 1 2

Mean −− 1.58 −− 3.50 −− 6.05
SD
CV
1 −−
−−
0.060
3.8
2 −−
−−
0.147
4.2
3 −−
−−
0.248
4.1
# Points −− 307 −− 309 −− 307
# Labs 2 2 2

Mean 1.54 1.54 3.40 3.40 5.94 5.94
SD
CV
1 0.040
2.6
0.046
3.0
2 0.063
1.9
0.079
2.3
3 0.101
1.7
0.144
2.4
# Points 1284 39056 178 13915 1289 41182
# Labs 23 86 5 36 23 94

Mean −− 1.53 −− 3.41 −− 5.93
SD
CV
1 −−
−−
0.031
2.0
2−−
−−
0.060
1.8
3 −−
−−
0.096
1.6
# Points −− 490 −− 487 −− 488
# Labs 1 1 1

Mean 1.51 1.54 3.35 3.44 −− 5.99
SD
CV
1 0.018
1.2
0.029
1.9
2 0.026
0.8
0.051
1.5
3 −−
−−
0.075
1.3
# Points 15 1312 15 1328 −− 1249
# Labs 1 3 1 3 2
Roche cobas c 303/503 • Roche LACT2, REF 08057940

Mean 1.57 1.54 −− 3.42 6.00 5.96
SD
CV
1 0.041
2.6
0.045
3.0
2 −−
−−
0.040
1.2
3 0.071
1.2
0.136
2.3
# Points 239 7538 −− 556 241 7705
# Labs 6 18 2 6 18

Mean 1.51 1.51 3.40 3.40 5.97 5.97
SD
CV
1 0.032
2.1
0.034
2.2
2 0.092
2.7
0.065
1.9
3 0.173
2.9
0.116
1.9
# Points 62 711 63 712 62 716
# Labs 2 2 2 2 2 2

Mean 1.53 1.53 3.37 3.37 5.83 5.84
SD
CV
1 0.011
0.7
0.037
2.4
2 0.033
1.0
0.130
3.9
3 0.078
1.3
0.139
2.4
# Points 31 1056 31 723 31 1048
# Labs 1 3 1 2 1 3

Mean −− 1.54 −− −− −− 5.91
SD
CV
1 −−
−−
0.039
2.5
2 −−
−−
−−
−−
3 −−
−−
0.092
1.6
# Points −− 295 −− −− −− 301
# Labs 1 1
Mean −− 1.64 −− 3.71 −− 6.48
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
0.000
0.0
3 −−
−−
0.000
0.0
# Points −− 1 −− 1 −− 1
# Labs 1 1 1

Mean 1.39 1.37 −− 3.20 5.82 5.81
SD
CV
1 0.020
1.4
0.064
4.6
2 −−
−−
0.097
3.0
3 0.080
1.4
0.166
2.9
# Points 32 1253 −− 1193 32 2258
# Labs 1 4 3 1 5
Siemens ADVIA Chemistry Systems • Abbott ARCH Lactic Acid, REF 9P18
Mean −− 1.58 −− 3.33 −− 5.53
SD
CV
1 −−
−−
0.089
5.6
−−
−−
20.086
2.6
3 −−
−−
0.139
2.5
# Points −− 333 −− 330 −− 333
# Labs 1 1 1

Mean 1.47 1.38 3.29 3.22 5.87 5.87
SD
CV
1 0.116
7.9
0.045
3.3
2 0.058
1.7
0.084
2.6
3 0.127
2.2
0.150
2.6
# Points 81 17780 39 7712 119 16617
# Labs 2 49 2 21 4 47
Siemens Atellica CH Analyzer • Siemens Atellica CH Lactate_2, REF 11532568

Mean −− 1.37 −− −− −− 5.91
SD
CV
1 −−
−−
0.038
2.7
−−
−−
2 −−
−−
3 −−
−−
0.147
2.5
# Points −− 1443 −− −− −− 1195
# Labs 4 4

Mean 1.39 1.37 3.28 3.22 5.72 5.74
SD
CV
1 0.104
7.5
0.116
8.5
2 0.110
3.4
0.155
4.8
3 0.164
2.9
0.202
3.5
# Points 1044 55216 306 9715 905 50588
# Labs 34 132 9 24 30 126

Mean 1.59 1.50 3.49 3.42 6.07 6.01
SD
CV
1 0.065
4.1
0.090
6.0
2 0.074
2.1
0.101
3.0
3 0.144
2.4
0.156
2.6
# Points 1072 86490 79 15602 986 85500
# Labs 38 202 5 44 37 200

Mean 0.155 0.952 3.25 3.27 3.79 4.16
SD
CV
1 0.003
2.1
0.604
63.4
2 0.040
1.2
0.075
2.3
3 2.24
59.3
2.12
50.9
# Points 15 950 32 472 46 1304
# Labs 1 4 1 2 2 5

Mean 1.40 1.38 3.20 3.30 5.53 5.47
SD
CV
1 0.049
3.5
0.044
3.2
2 0.050
1.6
0.081
2.5
3 0.161
2.9
0.138
2.5
# Points 110 9927 23 2393 112 9902
# Labs 6 52 1 13 6 51

Mean −− 1.29 −− −− −− 5.08
SD
CV
1 −−
−−
0.059
4.6
2 −−
−−
−−
−−
3 −−
−−
0.126
2.5
# Points −− 355 −− −− −− 353
# Labs 1 1

Mean −− 1.38 −− 3.23 −− 5.44
SD
CV
1 −−
−−
0.057
4.2
2 −−
−−
0.436
13.5
3 −−
−−
0.118
2.2
# Points −− 7468 −− 2793 −− 5276
# Labs 54 17 50

Mean 1.40 1.40 3.24 3.26 5.43 5.50
SD
CV
1 0.036
2.6
0.036
2.6
2 0.076
2.3
0.072
2.2
3 0.101
1.9
0.130
2.4
# Points 427 8524 119 1711 414 39476
# Labs 17 49 6 15 16 47

Mean −− 1.39 −− 3.12 −− 5.44
SD
CV
1 −−
−−
0.033
2.4
2 −−
−−
0.719
23.1
3 −−
−−
0.117
2.1
# Points −− 3286 −− 1115 −− 3298
# Labs 30 10 29

Mean −− 1.37 −− 3.23 −− 5.38
SD
CV
1 −−
−−
0.030
2.2
2 −−
−−
0.049
1.5
3 −−
−−
0.099
1.8
# Points −− 182 −− 212 −− 92
# Labs 1 1 1

Mean 1.49 1.46 3.33 3.30 5.83 5.80
SD
CV
1 0.125
8.4
0.122
8.4
2 0.121
3.6
0.296
9.0
3 0.385
6.6
0.368
6.3
# Points 5221 293K 1084 78880 4990 317K
# Labs 156 843 44 273 154 832
Lactic Acid Enzymatic mg/dL

Mean 13.74 13.78 30.58 29.10 54.44 54.57
SD
CV
1 0.321
2.3
0.407
3.0
2 0.557
1.8
5.88
20.2
3 0.990
1.8
1.58
2.9
# Points 297 10460 90 4257 228 10345
# Labs 9 32 4 16 7 30
Mean 14.02 13.77 31.08 30.34 55.74 54.76
SD
CV
1 0.445
3.2
0.435
3.2
2
0.450
1.4
0.726
2.4
3 1.01
1.8
1.65
3.0
# Points 96 14316 31 6036 95 13397
# Labs 3 38 1 21 3 35

Mean 12.81 12.65 28.82 28.73 49.90 49.29
SD
CV
1 0.402
3.1
1.02
8.1
2 1.00
3.5
1.08
3.8
3 1.40
2.8
3.96
8.0
# Points 338 16857 68 5553 354 16178
# Labs 10 52 4 24 12 48

Mean −− −− −− 25.90 −− 43.50
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.21
4.7
3 −−
−−
2.69
6.2
# Points −− −− −− 591 −− 590
# Labs 2 2

Mean −− −− 32.48 32.29 57.22 56.63
SD
CV
1 −−
−−
−−
−−
2 2.03
6.3
1.43
4.4
3 3.96
6.9
2.40
4.2
# Points −− −− 5 461 4 461
# Labs 1 2 1 2

Mean 13.03 13.67 −− 29.73 49.18 50.91
SD
CV
1 0.579
4.4
0.516
3.8
2 −−
−−
0.733
2.5
3 1.62
3.3
1.15
2.3
# Points 78 6503 −− 522 68 6518
# Labs 2 18 3 2 18

Beckman Coulter UniCel DxC Series • Beckman Coulter LACT, REF A95550
Mean −− 13.66 −− 29.37 −− 50.67
SD
CV
1 −−
−−
0.595
4.4
−−
−−
20.902
3.1
3 −−
−−
1.21
2.4
# Points −− 423 −− 335 −− 387
# Labs 3 2 3
Beckman Coulter UniCel DxC Series • Pointe Scientific, Inc. (MedTest Dx)
Mean −− 1.63 −− 3.34 −− 5.55
SD
CV
1 −−
−−
0.056
3.4
2
−−
−−
0.076
2.3
3 −−
−−
0.117
2.1
# Points −− 275 −− 277 −− 277
# Labs 2 2 2

Mean −− −− 28.76 30.58 56.85 54.44
SD
CV
1 −−
−−
−−
−−
2 0.240
0.8
2.01
6.6
3 0.480
0.8
1.96
3.6
# Points −− −− 5 59 4 58
# Labs 1 2 1 2

Mean −− 14.26 −− 31.57 −− 54.55
SD
CV
1 −−
−−
0.537
3.8
2 −−
−−
1.32
4.2
3 −−
−−
2.24
4.1
# Points −− 307 −− 309 −− 307
# Labs 2 2 2

Mean 13.86 13.85 30.61 30.64 53.52 53.56
SD
CV
1 0.358
2.6
0.418
3.0
2 0.566
1.9
0.715
2.3
3 0.914
1.7
1.30
2.4
# Points 1284 39056 178 13915 1289 41182
# Labs 23 86 5 36 23 94

Mean −− 13.78 −− 30.68 −− 53.40
SD
CV
1 −−
−−
0.282
2.0
−−
−−
2 0.541
1.8
3 −−
−−
0.866
1.6
# Points −− 490 −− 487 −− 488
# Labs 1 1 1

Mean 13.62 13.83 30.22 30.95 −− 53.98
SD
CV
1 0.163
1.2
0.258
1.9
2 0.236
0.8
0.458
1.5
3 −−
−−
0.676
1.3
# Points 15 1312 15 1328 −− 1249
# Labs 1 3 1 3 2
Roche cobas c 303/503 • Roche LACT2, REF 08057940

Mean 14.12 13.88 −− 30.78 54.09 53.67
SD
CV
1 0.370
2.6
0.410
3.0
2 −−
−−
0.357
1.2
3 0.642
1.2
1.23
2.3
# Points 239 7538 −− 556 241 7705
# Labs 6 18 2 6 18

Mean 13.57 13.57 30.61 30.67 53.81 53.77
SD
CV
1 0.290
2.1
0.302
2.2
2 0.830
2.7
0.589
1.9
3 1.56
2.9
1.04
1.9
# Points 62 711 63 712 62 716
# Labs 2 2 2 2 2 2

Mean 13.80 13.83 30.40 30.35 52.50 52.57
SD
CV
1 0.100
0.7
0.335
2.4
2 0.300
1.0
1.17
3.9
3 0.700
1.3
1.26
2.4
# Points 31 1056 31 723 31 1048
# Labs 1 3 1 2 1 3

Mean −− 13.91 −− −− −− 53.25
SD
CV
1 −−
−−
0.348
2.5
2 −−
−−
−−
−−
3 −−
−−
0.825
1.6
# Points −− 295 −− −− −− 301
# Labs 1 1
Mean −− 14.77 −− 33.42 −− 58.38
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
0.000
0.0
3 −−
−−
0.000
0.0
# Points −− 1 −− 1 −− 1
# Labs 1 1 1

Mean 12.52 12.39 −− 28.80 52.43 52.34
SD
CV
1 0.180
1.4
0.574
4.6
2 −−
−−
0.874
3.0
3 0.721
1.4
1.50
2.9
# Points 32 1253 −− 1193 32 2258
# Labs 1 4 3 1 5
Siemens ADVIA Chemistry Systems • Abbott ARCH Lactic Acid, REF 9P18
Mean −− 14.22 −− 30.00 −− 49.86
SD
CV
1 −−
−−
0.802
5.6
−−
−−
2 0.776
2.6
3 −−
−−
1.25
2.5
# Points −− 333 −− 330 −− 333
# Labs 1 1 1

Mean 13.24 12.44 29.66 28.97 52.88 52.85
SD
CV
1 1.05
7.9
0.409
3.3
2 0.519
1.7
0.757
2.6
3 1.14
2.2
1.35
2.6
# Points 81 17780 39 7712 119 16617
# Labs 2 49 2 21 4 47

Mean −− 12.37 −− −− −− 53.23
SD
CV
1 −−
−−
0.339
2.7
2−−
−−
−−
−−
3 −−
−−
1.32
2.5
# Points −− 1443 −− −− −− 1195
# Labs 4 4

Mean 12.56 12.36 29.51 28.99 51.54 51.68
SD
CV
1 0.940
7.5
1.05
8.5
2 0.993
3.4
1.40
4.8
3 1.47
2.9
1.82
3.5
# Points 1044 55216 306 9715 905 50588
# Labs 34 132 9 24 30 126

Mean 14.33 13.53 31.42 30.83 54.72 54.11
SD
CV
1 0.582
4.1
0.813
6.0
2 0.667
2.1
0.911
3.0
3 1.30
2.4
1.40
2.6
# Points 1072 86490 79 15602 986 85500
# Labs 38 202 5 44 37 200

Mean 1.40 8.58 29.28 29.47 34.11 37.47
SD
CV
1 0.030
2.1
5.44
63.4
2 0.360
1.2
0.679
2.3
3 20.22
59.3
19.08
50.9
# Points 15 950 32 472 46 1304
# Labs 1 4 1 2 2 5

Mean 12.59 12.46 28.79 29.69 49.79 49.30
SD
CV
1 0.441
3.5
0.399
3.2
2 0.453
1.6
0.734
2.5
3 1.45
2.9
1.24
2.5
# Points 110 9927 23 2393 112 9902
# Labs 6 52 1 13 6 51

Mean −− 11.59 −− −− −− 45.75
SD
CV
1 −−
−−
0.532
4.6
2 −−
−−
−−
−−
3 −−
−−
1.13
2.5
# Points −− 355 −− −− −− 353
# Labs 1 1

Mean −− 12.42 −− 29.12 −− 48.99
SD
CV
1 −−
−−
0.517
4.2
2 −−
−−
3.93
13.5
3 −−
−−
1.06
2.2
# Points −− 7468 −− 2793 −− 5276
# Labs 54 17 50

Mean 12.57 12.65 29.17 29.34 48.93 49.55
SD
CV
1 0.324
2.6
0.329
2.6
2 0.681
2.3
0.646
2.2
3 0.909
1.9
1.17
2.4
# Points 427 8524 119 1711 414 39476
# Labs 17 49 6 15 16 47

Mean −− 12.55 −− 28.08 −− 49.05
SD
CV
1 −−
−−
0.299
2.4
2 −−
−−
6.48
23.1
3 −−
−−
1.05
2.1
# Points −− 3286 −− 1115 −− 3298
# Labs 30 10 29

Mean −− 12.31 −− 29.14 −− 48.43
SD
CV
1 −−
−−
0.274
2.2
2 −−
−−
0.442
1.5
3 −−
−−
0.895
1.8
# Points −− 182 −− 212 −− 92
# Labs 1 1 1

Mean 13.43 13.13 29.98 29.76 52.53 52.28
SD
CV
1 1.12
8.4
1.10
8.4
2 1.09
3.6
2.67
9.0
3 3.47
6.6
3.31
6.3
# Points 5221 293K 1084 78880 4990 317K
# Labs 156 843 44 273 154 832
Lactic Acid Lactate to pyruvate mEq/L

Mean 1.52 1.54 3.37 3.37 6.13 6.07
SD
CV
1 0.038
2.5
0.043
2.8
2 0.056
1.7
0.064
1.9
3 0.070
1.1
0.155
2.6
# Points 53 8826 54 5543 41 8455
# Labs 3 37 3 22 2 36
Mean −− 1.54 −− 3.43 −− 6.18
SD
CV
1 −−
−−
0.041
2.7
−−
−−
2 0.050
1.5
3 −−
−−
0.130
2.1
# Points −− 676 −− 213 −− 675
# Labs 4 1 4
Abbott ARCHITECT/Alinity (c, i, ci models) • Diakon (DiaSys)

Mean 1.46 1.40 3.08 3.03 5.21 5.17
SD
CV
1 0.050
3.4
0.046
3.3
2
0.080
2.6
0.069
2.3
3 0.140
2.7
0.143
2.8
# Points 19 362 19 404 19 409
# Labs 1 1 1 1 1 1

Mean 1.43 1.41 3.21 3.19 5.56 5.55
SD
CV
1 0.041
2.9
0.106
7.5
2 0.076
2.4
0.114
3.6
3 0.113
2.0
0.169
3.0
# Points 180 13835 118 8427 186 12969
# Labs 5 34 3 18 5 35

Mean −− 1.52 −− −− −− 5.63
SD
CV
1 −−
−−
0.054
3.6
2 −−
−−
−−
−−
3 −−
−−
0.134
2.4
# Points −− 1169 −− −− −− 1148
# Labs 5 5

Mean −− 1.53 −− −− −− 5.97
SD
CV
1 −−
−−
0.026
1.7
2 −−
−−
−−
−−
3 −−
−−
0.083
1.4
# Points −− 196 −− −− −− 196
# Labs 1 1

Mean 1.55 1.55 −− 3.41 6.01 5.96
SD
CV
1 0.042
2.7
0.049
3.1
2 −−
−−
0.065
1.9
3 0.141
2.3
0.134
2.3
# Points 387 4158 −− 1124 389 5260
# Labs 5 10 4 5 12

Mean 1.49 1.50 3.32 3.36 −− −−
SD
CV
1 0.020
1.3
0.026
1.7
2 0.030
0.9
0.053
1.6
3 −−
−−
−−
−−
# Points 83 961 84 963 −− −−
# Labs 1 1 1 1

Mean 1.38 1.36 3.16 3.23 5.78 5.96
SD
CV
1 0.023
1.6
0.030
2.2
2 0.042
1.3
0.066
2.0
3 0.102
1.8
0.131
2.2
# Points 55 7396 22 6558 56 6361
# Labs 2 8 1 7 2 6

Mean −− 1.39 −− 3.25 −− 5.88
SD
CV
1 −−
−−
0.066
4.8
2 −−
−−
0.113
3.5
3 −−
−−
0.148
2.5
# Points −− 5060 −− 1728 −− 5000
# Labs 10 2 10
Siemens Atellica CH Analyzer • Siemens Atellica CH Lac_3 REF 11537218

Mean 1.60 1.60 −− −− 5.87 5.87
SD
CV
1 0.039
2.4
0.039
2.4
2
−−
−−
−−
−−
3 0.073
1.2
0.073
1.2
# Points 46 46 −− −− 48 48
# Labs 2 2 2 2

Mean 1.39 1.39 −− −− 5.89 5.89
SD
CV
1 0.019
1.4
0.042
3.1
2
−−
−−
−−
−−
3 0.081
1.4
0.148
2.5
# Points 34 1235 −− −− 34 1231
# Labs 2 4 2 4

Mean 1.60 1.35 −− 3.31 6.23 5.70
SD
CV
1 0.082
5.1
0.115
8.6
2 −−
−−
0.129
3.9
3 0.100
1.6
0.248
4.3
# Points 7 4584 −− 45 9 4868
# Labs 1 12 1 1 12

Mean 1.58 1.50 3.48 3.41 6.05 6.01
SD
CV
1 0.061
3.8
0.092
6.1
2 0.083
2.4
0.117
3.4
3 0.130
2.2
0.159
2.7
# Points 834 73670 296 16934 679 70426
# Labs 25 164 11 44 22 165

Mean −− 1.43 −− 3.31 −− −−
SD
CV
1 −−
−−
0.046
3.2
2 −−
−−
0.080
2.4
3 −−
−−
−−
−−
# Points −− 155 −− 155 −− −−
# Labs 4 4

Mean 1.37 1.39 −− 3.27 5.44 5.45
SD
CV
1 0.049
3.6
0.051
3.6
2 −−
−−
0.077
2.4
3 0.181
3.3
0.141
2.6
# Points 64 3582 −− 1155 65 3430
# Labs 3 28 10 3 25

Mean −− 1.37 −− 3.23 −− 5.38
SD
CV
1 −−
−−
0.051
3.7
2 −−
−−
0.092
2.8
3 −−
−−
0.134
2.5
# Points −− 1855 −− 917 −− 1749
# Labs 18 11 16

Mean 1.42 1.40 3.27 3.24 5.40 5.41
SD
CV
1 0.049
3.4
0.040
2.8
2 0.106
3.2
0.076
2.3
3 0.181
3.3
0.132
2.4
# Points 127 4251 128 2372 127 4214
# Labs 5 26 5 15 5 24

Mean 1.36 1.39 −− 3.27 5.24 5.39
SD
CV
1 0.026
1.9
0.047
3.4
2 −−
−−
0.110
3.3
3 0.086
1.6
0.187
3.5
# Points 64 1638 −− 929 64 1504
# Labs 2 17 8 2 14

Mean −− −− −− 3.23 −− 5.42
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.029
0.9
3 −−
−−
0.048
0.9
# Points −− −− −− 22 −− 22
# Labs 1 1

Mean −− 1.43 −− −− −− 5.54
SD
CV
1 −−
−−
0.017
1.2
2 −−
−−
−−
−−
3 −−
−−
0.063
1.1
# Points −− 69 −− −− −− 64
# Labs 2 2
Method Group • Lactate to pyruvate

Mean 1.52 1.47 3.35 3.31 5.86 5.89
SD
CV
1 0.090
5.9
0.101
6.9
2 0.146
4.3
0.138
4.2
3 0.300
5.1
0.266
4.5
# Points 1953 134K 721 47533 1717 128K
# Labs 57 390 25 151 52 377
Lactic Acid Lactate to pyruvate mg/dL

Mean 13.69 13.85 30.32 30.35 55.27 54.64
SD
CV
1 0.345
2.5
0.384
2.8
2 0.501
1.7
0.573
1.9
3 0.628
1.1
1.40
2.6
# Points 53 8826 54 5543 41 8455
# Labs 3 37 3 22 2 36
Mean −− 13.87 −− 30.92 −− 55.71
SD
CV
1 −−
−−
0.369
2.7
2
−−
−−
0.453
1.5
3 −−
−−
1.17
2.1
# Points −− 676 −− 213 −− 675
# Labs 4 1 4

Mean 13.15 12.64 27.75 27.32 46.94 46.55
SD
CV
1 0.450
3.4
0.416
3.3
2
0.721
2.6
0.623
2.3
3 1.26
2.7
1.29
2.8
# Points 19 362 19 404 19 409
# Labs 1 1 1 1 1 1

Mean 12.89 12.73 28.90 28.73 50.10 49.99
SD
CV
1 0.372
2.9
0.957
7.5
2 0.687
2.4
1.03
3.6
3 1.01
2.0
1.52
3.0
# Points 180 13835 118 8427 186 12969
# Labs 5 34 3 18 5 35

Mean −− 13.65 −− −− −− 50.72
SD
CV
1 −−
−−
0.488
3.6
2 −−
−−
−−
−−
3 −−
−−
1.21
2.4
# Points −− 1169 −− −− −− 1148
# Labs 5 5

Mean −− 13.75 −− −− −− 53.80
SD
CV
1 −−
−−
0.234
1.7
2 −−
−−
−−
−−
3 −−
−−
0.750
1.4
# Points −− 196 −− −− −− 196
# Labs 1 1

Mean 13.92 13.95 −− 30.76 54.13 53.68
SD
CV
1 0.382
2.7
0.438
3.1
2 −−
−−
0.584
1.9
3 1.27
2.3
1.21
2.3
# Points 387 4158 −− 1124 389 5260
# Labs 5 10 4 5 12

Mean 13.42 13.51 29.91 30.25 −− −−
SD
CV
1 0.180
1.3
0.236
1.7
2 0.270
0.9
0.475
1.6
3 −−
−−
−−
−−
# Points 83 961 84 963 −− −−
# Labs 1 1 1 1

Mean 12.43 12.25 28.44 29.08 52.07 53.68
SD
CV
1 0.203
1.6
0.273
2.2
2 0.380
1.3
0.595
2.0
3 0.923
1.8
1.18
2.2
# Points 55 7396 22 6558 56 6361
# Labs 2 8 1 7 2 6

Mean −− 12.55 −− 29.26 −− 53.02
SD
CV
1 −−
−−
0.598
4.8
2 −−
−−
1.02
3.5
3 −−
−−
1.33
2.5
# Points −− 5060 −− 1728 −− 5000
# Labs 10 2 10
Siemens Atellica CH Analyzer • Siemens Atellica CH Lac_3 REF 11537218

Mean 14.43 14.43 −− −− 52.91 52.91
SD
CV
1 0.347
2.4
0.347
2.4
2
−−
−−
−−
−−
3 0.659
1.2
0.659
1.2
# Points 46 46 −− −− 48 48
# Labs 2 2 2 2

Mean 12.53 12.48 −− −− 53.05 53.07
SD
CV
1 0.173
1.4
0.381
3.1
2
−−
−−
−−
−−
3 0.730
1.4
1.34
2.5
# Points 34 1235 −− −− 34 1231
# Labs 2 4 2 4

Mean 14.41 12.12 −− 29.79 56.16 51.36
SD
CV
1 0.736
5.1
1.04
8.6
2 −−
−−
1.16
3.9
3 0.901
1.6
2.23
4.3
# Points 7 4584 −− 45 9 4868
# Labs 1 12 1 1 12

Mean 14.22 13.49 31.37 30.73 54.47 54.13
SD
CV
1 0.546
3.8
0.826
6.1
2 0.749
2.4
1.06
3.4
3 1.17
2.2
1.44
2.7
# Points 834 73670 296 16934 679 70426
# Labs 25 164 11 44 22 165

Mean −− 12.84 −− 29.81 −− −−
SD
CV
1 −−
−−
0.414
3.2
2 −−
−−
0.717
2.4
3 −−
−−
−−
−−
# Points −− 155 −− 155 −− −−
# Labs 4 4

Mean 12.34 12.54 −− 29.48 48.98 49.14
SD
CV
1 0.446
3.6
0.456
3.6
2 −−
−−
0.696
2.4
3 1.63
3.3
1.27
2.6
# Points 64 3582 −− 1155 65 3430
# Labs 3 28 10 3 25

Mean −− 12.37 −− 29.12 −− 48.51
SD
CV
1 −−
−−
0.460
3.7
2 −−
−−
0.825
2.8
3 −−
−−
1.21
2.5
# Points −− 1855 −− 917 −− 1749
# Labs 18 11 16

Mean 12.75 12.65 29.42 29.17 48.65 48.69
SD
CV
1 0.439
3.4
0.358
2.8
2 0.952
3.2
0.685
2.3
3 1.63
3.3
1.18
2.4
# Points 127 4251 128 2372 127 4214
# Labs 5 26 5 15 5 24

Mean 12.28 12.56 −− 29.49 47.24 48.59
SD
CV
1 0.236
1.9
0.426
3.4
2 −−
−−
0.987
3.3
3 0.774
1.6
1.68
3.5
# Points 64 1638 −− 929 64 1504
# Labs 2 17 8 2 14

Mean −− −− −− 29.11 −− 48.81
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.261
0.9
3 −−
−−
0.437
0.9
# Points −− −− −− 22 −− 22
# Labs 1 1

Mean −− 12.85 −− −− −− 49.90
SD
CV
1 −−
−−
0.157
1.2
2 −−
−−
−−
−−
3 −−
−−
0.567
1.1
# Points −− 69 −− −− −− 64
# Labs 2 2

Mean 13.69 13.21 30.18 29.85 52.81 53.04
SD
CV
1 0.813
5.9
0.910
6.9
2 1.31
4.3
1.24
4.2
3 2.70
5.1
2.40
4.5
# Points 1953 134K 721 47533 1717 128K
# Labs 57 390 25 151 52 377
LD (Lactate Dehydrogenase) Dinitrophenyl hydrazine U/L @ 25° C

Mean −− 7261 −− 10648 −− 24898
SD
CV
1 −−
−−
330.4
4.6
2 −−
−−
216.5
2.0
3 −−
−−
597.2
2.4
# Points −− 350 −− 74 −− 276
# Labs 2 1 1

Mean −− 263.2 −− 411.6 −− 590.7
SD
CV
1 −−
−−
145.1
55.1
2 −−
−−
234.4
57.0
3 −−
−−
233.5
39.5
# Points −− 149 −− 149 −− 149
# Labs 2 2 2

Mean −− 3547 −− 7394 −− 21296
SD
CV
1 −−
−−
59.28
1.7
2 −−
−−
75.01
1.0
3 −−
−−
206.1
1.0
# Points −− 136 −− 135 −− 122
# Labs 1 1 1

Mean −− 5171 −− 3808 −− 17473
SD
CV
1 −−
−−
3218
62.2
2 −−
−−
4836
127.0
3 −−
−−
10446
59.8
# Points −− 499 −− 223 −− 547
# Labs 4 3 4
LD (Lactate Dehydrogenase) Dinitrophenyl hydrazine U/L @ 37° C

Mean 95.53 100.8 142.2 157.9 −− 372.7
SD
CV
1 2.30
2.4
4.20
4.2
2 4.40
3.1
6.49
4.1
3 −−
−−
8.41
2.3
# Points 26 153 26 743 −− 590
# Labs 1 1 1 4 3

Mean −− 129.7 −− −− −− 428.4
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− 1 −− −− −− 1
# Labs 1 1

Mean 132.9 129.7 190.6 188.4 429.6 418.8
SD
CV
1 5.00
3.8
4.29
3.3
2 11.28
5.9
7.84
4.2
3 6.60
1.5
12.08
2.9
# Points 62 184 62 184 62 184
# Labs 2 2 2 2 2 2

Mean −− 119.1 −− −− −− 406.3
SD
CV
1 −−
−−
3.28
2.8
2 −−
−−
−−
−−
3 −−
−−
6.18
1.5
# Points −− 529 −− −− −− 528
# Labs 1 1

Mean 121.8 118.2 176.3 164.0 429.6 392.9
SD
CV
1 17.68
14.5
9.78
8.3
2 24.24
13.7
13.92
8.5
3 6.60
1.5
20.55
5.2
# Points 88 867 88 927 62 1303
# Labs 3 5 3 6 2 7
LD (Lactate Dehydrogenase) L to P − IFCC Ref. Proc., Calibrated U/L @ 25° C

Mean −− 121.7 −− 181.7 −− 417.5
SD
CV
1 −−
−−
5.67
4.7
2 −−
−−
5.79
3.2
3 −−
−−
10.39
2.5
# Points −− 122 −− 114 −− 122
# Labs 1 1 1

Mean −− 123.1 −− 181.2 −− 404.3
SD
CV
1 −−
−−
2.78
2.3
2 −−
−−
2.97
1.6
3 −−
−−
5.90
1.5
# Points −− 835 −− 931 −− 940
# Labs 1 1 1
Method Group • L to P − IFCC Ref. Proc., Calibrated

Mean −− 122.9 −− 181.3 −− 405.8
SD
CV
1 −−
−−
3.32
2.7
2 −−
−−
3.39
1.9
3 −−
−−
7.81
1.9
# Points −− 957 −− 1045 −− 1062
# Labs 2 2 2

Mean 121.6 120.0 182.8 178.6 409.8 411.4
SD
CV
1 6.57
5.4
5.78
4.8
2 6.27
3.4
7.50
4.2
3 11.02
2.7
11.19
2.7
# Points 342 6225 174 1443 157 5536
# Labs 12 32 7 14 5 22
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c LDH, REF 07P74 (Factored, IFCC Correlated)
Mean 118.1 117.7 176.2 175.5 −− −−
SD
CV
1 2.92
2.5
3.48
3.0
2 3.33
1.9
3.68
2.1
3 −−
−−
−−
−−
# Points 26 125 26 125 −− −−
# Labs 1 1 1 1
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c LDH2, REF 04T99 (Factored, IFCC Correlated)
Mean 115.4 116.0 170.0 173.6 379.3 387.2
SD
CV
1 6.05
5.2
6.23
5.4
2 7.00
4.1
7.02
4.0
3 14.77
3.9
13.91
3.6
# Points 96 464 96 268 81 458
# Labs 7 8 7 7 6 7

Mean 118.4 118.9 175.0 175.5 403.7 405.8
SD
CV
1 5.67
4.8
5.62
4.7
26.66
3.8
7.05
4.0
3 11.11
2.8
11.92
2.9
# Points 1121 38308 967 24566 560 35447
# Labs 42 127 38 95 24 103

Mean 116.3 118.0 172.0 175.6 395.7 399.4
SD
CV
1 5.91
5.1
7.32
6.2
2 6.15
3.6
7.55
4.3
3 12.11
3.1
19.40
4.9
# Points 97 11904 130 16541 127 18868
# Labs 2 34 5 42 5 49

Mean −− −− 170.3 172.9 390.2 393.6
SD
CV
1 −−
−−
−−
−−
2 6.56
3.9
8.08
4.7
3 10.32
2.6
13.69
3.5
# Points −− −− 149 1865 150 1866
# Labs 3 4 3 4

Mean −− −− −− 178.2 −− 407.6
SD
CV
1 −−
−−
−−
−−
2 −−
−−
2.47
1.4
3 −−
−−
4.64
1.1
# Points −− −− −− 172 −− 171
# Labs 1 1

Mean −− −− −− 144.5 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
4.69
3.2
3 −−
−−
−−
−−
# Points −− −− −− 41 −− −−
# Labs 1

Mean −− −− −− 153.8 −− 377.2
SD
CV
1 −−
−−
−−
−−
2 −−
−−
10.87
7.1
3 −−
−−
12.80
3.4
# Points −− −− −− 106 −− 106
# Labs 1 1

Mean −− 123.9 −− −− −− −−
SD
CV
1 −−
−−
1.61
1.3
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 64 −− −− −− −−
# Labs 1

Mean 121.1 122.5 174.4 180.9 404.5 408.6
SD
CV
1 3.18
2.6
3.59
2.9
2 7.67
4.4
5.82
3.2
3 8.61
2.1
10.53
2.6
# Points 1157 41508 193 15516 1091 43380
# Labs 26 101 4 48 24 107

Mean 119.9 121.9 179.0 182.2 401.8 414.1
SD
CV
1 2.96
2.5
3.64
3.0
2 2.44
1.4
5.22
2.9
3 10.50
2.6
12.21
2.9
# Points 214 4990 173 5036 76 5001
# Labs 5 16 3 12 3 14
Roche cobas c 303/503 • Roche LDHI2, REF 08057958

Mean 120.2 120.7 175.2 179.1 401.8 404.4
SD
CV
1 1.93
1.6
2.47
2.0
2 3.10
1.8
2.34
1.3
3 3.72
0.9
7.80
1.9
# Points 272 6362 49 1943 143 6292
# Labs 8 26 2 8 5 23

Mean 119.8 119.7 176.7 177.2 405.1 407.6
SD
CV
1 1.90
1.6
2.40
2.0
2 2.93
1.7
3.23
1.8
3 4.80
1.2
7.18
1.8
# Points 95 1220 96 1226 14 268
# Labs 2 2 2 2 1 1

Mean −− 126.8 −− 182.0 −− 414.4
SD
CV
1 −−
−−
2.24
1.8
2 −−
−−
1.30
0.7
3 −−
−−
6.25
1.5
# Points −− 582 −− 37 −− 576
# Labs 3 1 3

Mean −− −− −− 175.0 −− 395.0
SD
CV
1 −−
−−
−−
−−
2 −−
−−
10.40
5.9
3 −−
−−
5.06
1.3
# Points −− −− −− 306 −− 251
# Labs 1 1
Mean −− −− −− 177.2 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
10.82
6.1
3 −−
−−
−−
−−
# Points −− −− −− 6 −− −−
# Labs 2

Mean −− −− −− 164.1 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
3.65
2.2
3 −−
−−
−−
−−
# Points −− −− −− 25 −− −−
# Labs 1

Mean 124.4 124.8 184.0 183.8 −− 419.3
SD
CV
1 2.14
1.7
3.11
2.5
2 3.08
1.7
4.50
2.4
3 −−
−−
8.74
2.1
# Points 59 2300 90 1685 −− 1967
# Labs 2 10 3 10 7

Mean 123.4 122.7 182.9 180.7 407.5 406.3
SD
CV
1 2.80
2.3
3.60
2.9
2 2.79
1.5
4.73
2.6
3 7.06
1.7
10.30
2.5
# Points 493 23953 401 12099 204 19141
# Labs 16 76 14 53 9 64

Mean 114.9 115.7 169.9 172.7 392.8 394.5
SD
CV
1 6.96
6.1
5.90
5.1
2 8.52
5.0
6.89
4.0
3 14.37
3.7
12.13
3.1
# Points 765 36704 235 8379 645 32624
# Labs 22 113 7 32 18 95

Mean 118.3 118.7 176.0 175.7 394.2 395.2
SD
CV
1 5.49
4.6
4.64
3.9
2 6.63
3.8
5.69
3.2
3 10.32
2.6
9.73
2.5
# Points 1890 180K 729 53073 1668 164K
# Labs 61 387 24 108 52 364

Mean −− −− 191.1 185.5 −− −−
SD
CV
1 −−
−−
−−
−−
2 6.44
3.4
11.65
6.3
3 −−
−−
−−
−−
# Points −− −− 19 26 −− −−
# Labs 1 1

Mean −− 123.7 −− −− −− 401.0
SD
CV
1 −−
−−
3.35
2.7
2 −−
−−
−−
−−
3 −−
−−
7.87
2.0
# Points −− 856 −− −− −− 873
# Labs 4 4

Mean −− 126.7 −− 193.0 −− 426.6
SD
CV
1 −−
−−
3.19
2.5
2 −−
−−
5.32
2.8
3 −−
−−
5.92
1.4
# Points −− 63 −− 64 −− 63
# Labs 1 1 1

Mean −− 78.36 −− −− −− 123.8
SD
CV
1 −−
−−
1.27
1.6
2 −−
−−
−−
−−
3 −−
−−
1.41
1.1
# Points −− 138 −− −− −− 138
# Labs 1 1

Mean −− 1.37 −− 3.22 −− 5.34
SD
CV
1 −−
−−
0.021
1.5
2 −−
−−
0.046
1.4
3 −−
−−
0.090
1.7
# Points −− 109 −− 108 −− 95
# Labs 1 1 1

Mean −− 129.1 −− 184.2 −− −−
SD
CV
1 −−
−−
4.54
3.5
2 −−
−−
4.83
2.6
3 −−
−−
−−
−−
# Points −− 15 −− 15 −− −−
# Labs 2 2

Mean −− 117.4 −− 175.9 −− 403.4
SD
CV
1 −−
−−
4.69
4.0
2 −−
−−
3.99
2.3
3 −−
−−
13.73
3.4
# Points −− 425 −− 38 −− 449
# Labs 1 1 2

Mean −− 119.6 −− −− −− 413.7
SD
CV
1 −−
−−
3.70
3.1
2 −−
−−
−−
−−
3 −−
−−
9.60
2.3
# Points −− 632 −− −− −− 630
# Labs 1 1

Mean −− 124.6 −− 184.1 −− 400.2
SD
CV
1 −−
−−
4.09
3.3
2 −−
−−
5.06
2.7
3 −−
−−
10.46
2.6
# Points −− 11843 −− 5988 −− 12322
# Labs 50 21 52

Mean 121.7 123.6 176.1 181.4 394.3 397.4
SD
CV
1 4.85
4.0
4.19
3.4
2 4.54
2.6
5.73
3.2
3 13.12
3.3
10.42
2.6
# Points 248 10236 109 2705 234 9539
# Labs 12 56 6 21 10 47

Mean 125.7 125.5 184.6 184.4 406.9 401.9
SD
CV
1 5.61
4.5
5.10
4.1
2 6.25
3.4
5.84
3.2
3 13.76
3.4
11.50
2.9
# Points 304 4093 206 1706 140 2857
# Labs 11 37 7 16 6 27

Mean 127.0 126.9 186.4 187.3 423.0 424.1
SD
CV
1 4.00
3.2
3.62
2.8
2 4.91
2.6
5.27
2.8
3 8.59
2.0
9.52
2.2
# Points 157 282 62 87 144 270
# Labs 7 7 4 4 6 6

Mean −− 117.1 −− −− −− 388.1
SD
CV
1 −−
−−
3.04
2.6
2 −−
−−
−−
−−
3 −−
−−
8.92
2.3
# Points −− 121 −− −− −− 122
# Labs 2 2
Method Group • L to P − IFCC Ref. Proc., Calibrated

Mean 119.6 119.6 176.8 177.2 399.2 399.5
SD
CV
1 5.80
4.8
5.99
5.0
2 7.57
4.3
9.18
5.2
3 12.95
3.2
15.14
3.8
# Points 7368 384K 3904 155K 5466 364K
# Labs 237 1102 138 512 178 1010
LD (Lactate Dehydrogenase) Lactate to pyruvate U/L @ 25° C

Mean −− 94.81 −− 146.6 −− 330.0
SD
CV
1 −−
−−
5.31
5.6
2 −−
−−
2.78
1.9
3 −−
−−
12.53
3.8
# Points −− 490 −− 20 −− 497
# Labs 3 1 3

Mean −− 95.42 −− −− −− 323.4
SD
CV
1 −−
−−
2.69
2.8
2 −−
−−
−−
−−
3 −−
−−
7.26
2.2
# Points −− 693 −− −− −− 676
# Labs 2 2

Mean −− 119.5 −− −− −− 401.0
SD
CV
1 −−
−−
2.77
2.3
2 −−
−−
−−
−−
3 −−
−−
8.69
2.2
# Points −− 385 −− −− −− 382
# Labs 2 2

Mean −− 122.3 −− −− −− 410.8
SD
CV
1 −−
−−
1.79
1.5
2 −−
−−
−−
−−
3 −−
−−
4.75
1.2
# Points −− 984 −− −− −− 975
# Labs 2 2

Mean 121.7 121.9 −− −− 410.5 409.1
SD
CV
1 1.70
1.4
1.80
1.5
2 −−
−−
−−
−−
3 3.32
0.8
5.34
1.3
# Points 73 1610 −− −− 69 1593
# Labs 2 2 2 2

Mean −− 117.7 −− 178.7 −− −−
SD
CV
1 −−
−−
3.66
3.1
2 −−
−−
5.02
2.8
3 −−
−−
−−
−−
# Points −− 42 −− 27 −− −−
# Labs 1 1

Mean 121.7 111.7 −− 165.0 410.5 377.2
SD
CV
1 1.70
1.4
13.00
11.6
2 −−
−−
16.56
10.0
3 3.32
0.8
40.22
10.7
# Points 73 3220 −− 47 69 3148
# Labs 2 10 2 2 9

Mean 105.0 103.2 −− −− 353.0 345.6
SD
CV
1 2.00
1.9
2.35
2.3
2 −−
−−
−−
−−
3 5.00
1.4
6.53
1.9
# Points 22 402 −− −− 22 402
# Labs 1 1 1 1

Mean 105.0 103.2 −− −− 353.0 345.6
SD
CV
1 2.00
1.9
2.35
2.3
2 −−
−−
−−
−−
3 5.00
1.4
6.53
1.9
# Points 22 402 −− −− 22 402
# Labs 1 1 1 1

Mean 114.9 119.4 167.5 177.6 400.6 409.1
SD
CV
1 6.06
5.3
5.49
4.6
2 5.50
3.3
6.86
3.9
3 19.92
5.0
14.09
3.4
# Points 124 8106 49 6528 89 7928
# Labs 4 27 2 16 3 26

Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c LDH2, REF 04T99 (Factored, IFCC Correlated)
Mean 113.5 111.4 164.5 162.2 371.8 369.9
SD
CV
1 3.18
2.8
3.44
3.1
2 2.70
1.6
3.55
2.2
3 4.64
1.2
5.66
1.5
# Points 36 378 17 188 19 186
# Labs 1 1 1 1 1 1

Mean −− −− −− 178.6 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
5.42
3.0
3 −−
−−
−−
−−
# Points −− −− −− 78 −− −−
# Labs 1

Mean 98.91 100.0 148.0 147.1 335.4 330.0
SD
CV
1 6.55
6.6
6.59
6.6
2 11.32
7.6
9.35
6.4
3 15.21
4.5
13.43
4.1
# Points 1681 48031 1384 24599 642 36636
# Labs 56 155 46 95 22 101

Mean −− 86.82 −− −− −− −−
SD
CV
1 −−
−−
3.10
3.6
2−−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 23 −− −− −− −−
# Labs 1

Mean 96.29 107.7 157.7 160.0 −− −−
SD
CV
1 7.92
8.2
5.88
5.5
2 4.53
2.9
5.31
3.3
3 −−
−−
−−
−−
# Points 24 267 24 197 −− −−
# Labs 1 1 1 1

Mean 115.3 120.3 168.1 177.4 394.0 403.8
SD
CV
1 4.98
4.3
6.63
5.5
2 6.41
3.8
8.65
4.9
3 11.88
3.0
18.02
4.5
# Points 82 22682 18 21464 82 23152
# Labs 5 59 1 56 4 61

Mean −− 109.1 −− −− −− 370.4
SD
CV
1 −−
−−
4.66
4.3
2 −−
−−
−−
−−
3 −−
−−
19.78
5.3
# Points −− 218 −− −− −− 218
# Labs 1 1

Mean −− 96.71 144.1 142.7 −− −−
SD
CV
1 −−
−−
3.50
3.6
2
2.83
2.0
5.14
3.6
3 −−
−−
−−
−−
# Points −− 190 62 286 −− −−
# Labs 2 2 2

Mean −− 106.7 −− 160.6 −− 377.5
SD
CV
1 −−
−−
3.24
3.0
2 −−
−−
4.46
2.8
3 −−
−−
9.97
2.6
# Points −− 141 −− 140 −− 140
# Labs 1 1 1

Mean 114.2 117.6 171.2 175.1 391.0 400.3
SD
CV
1 3.16
2.8
3.31
2.8
2 4.09
2.4
4.66
2.7
3 9.08
2.3
9.43
2.4
# Points 64 660 64 660 64 660
# Labs 2 2 2 2 2 2

Mean −− −− 166.4 181.4 379.0 409.5
SD
CV
1 −−
−−
−−
−−
2 0.890
0.5
6.52
3.6
3 0.820
0.2
13.46
3.3
# Points −− −− 5 721 4 719
# Labs 1 2 1 2

Mean −− 96.92 −− 143.0 −− 329.2
SD
CV
1 −−
−−
2.82
2.9
2 −−
−−
3.69
2.6
3 −−
−−
9.18
2.8
# Points −− 6961 −− 2036 −− 6255
# Labs 26 7 22

Mean −− 115.7 −− −− −− −−
SD
CV
1 −−
−−
3.69
3.2
2
−−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 62 −− −− −− −−
# Labs 1

Mean −− −− 177.1 175.4 401.6 398.6
SD
CV
1 −−
−−
−−
−−
2 6.71
3.8
9.25
5.3
3 12.75
3.2
19.02
4.8
# Points −− −− 41 230 39 233
# Labs 3 3 3 3

Mean −− 95.52 −− −− −− −−
SD
CV
1 −−
−−
4.10
4.3
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 23 −− −− −− −−
# Labs 1
Fuji Dri−Chem Series • Fuji Dri−Chem LDH−PIII, REF 9903190

Mean 91.00 92.62 146.0 147.0 −− −−
SD
CV
1 0.000
0.0
6.65
7.2
2
0.000
0.0
6.47
4.4
3 −−
−−
−−
−−
# Points 1 37 1 42 −− −−
# Labs 1 2 1 2

Mean −− 120.7 −− 183.6 −− 400.5
SD
CV
1 −−
−−
5.94
4.9
2 −−
−−
5.62
3.1
3 −−
−−
16.13
4.0
# Points −− 4483 −− 2892 −− 4492
# Labs 12 7 12

Mean −− 115.1 −− −− −− 396.7
SD
CV
1 −−
−−
5.06
4.4
2 −−
−−
−−
−−
3 −−
−−
10.87
2.7
# Points −− 89 −− −− −− 91
# Labs 1 1

Mean −− −− 172.8 175.4 −− 400.2
SD
CV
1 −−
−−
−−
−−
2
6.34
3.7
6.40
3.6
3 −−
−−
12.58
3.1
# Points −− −− 23 184 −− 175
# Labs 1 1 1

Mean −− 123.8 −− −− −− 397.7
SD
CV
1 −−
−−
9.38
7.6
2 −−
−−
−−
−−
3 −−
−−
19.59
4.9
# Points −− 16 −− −− −− 16
# Labs 1 1

Mindray BS Series
Mean −− 121.8 −− 183.1 −− 407.4
SD
CV
1 −−
−−
3.06
2.5
2 −−
−−
5.36
2.9
3 −−
−−
11.20
2.8
# Points −− 422 −− 427 −− 430
# Labs 3 2 2
Mindray CL Series
Mean −− −− −− 175.1 −− 394.4
SD
CV
1 −−
−−
−−
−−
2 −−
−−
6.12
3.5
3 −−
−−
11.51
2.9
# Points −− −− −− 261 −− 262
# Labs 2 2

Mean 122.6 123.2 178.8 181.6 409.7 410.8
SD
CV
1 3.81
3.1
3.51
2.9
2 7.89
4.4
5.14
2.8
3 13.00
3.2
10.73
2.6
# Points 190 15124 97 11373 161 17028
# Labs 7 41 4 33 6 48

Mean 123.1 122.5 182.1 180.8 413.0 410.4
SD
CV
1 1.99
1.6
4.17
3.4
2 2.75
1.5
4.58
2.5
3 3.80
0.9
9.67
2.4
# Points 58 2175 61 2136 50 2010
# Labs 2 6 2 4 2 6

Mean −− 121.7 −− −− −− 406.5
SD
CV
1 −−
−−
2.71
2.2
2 −−
−−
−−
−−
3 −−
−−
6.96
1.7
# Points −− 22 −− −− −− 22
# Labs 1 1

Mean 120.5 120.2 179.1 178.4 415.4 407.8
SD
CV
1 2.29
1.9
2.36
2.0
2 3.01
1.7
2.86
1.6
3 5.62
1.4
7.12
1.7
# Points 49 464 51 719 48 745
# Labs 1 2 1 2 1 3

Mean −− 128.9 −− −− −− 424.0
SD
CV
1 −−
−−
2.28
1.8
2 −−
−−
−−
−−
3 −−
−−
7.44
1.8
# Points −− 119 −− −− −− 125
# Labs 1 1

Mean 128.1 130.6 186.2 193.3 426.7 441.2
SD
CV
1 3.16
2.5
23.23
17.8
2 9.38
5.0
32.76
16.9
3 4.43
1.0
67.45
15.3
# Points 31 567 31 567 31 567
# Labs 1 2 1 2 1 2

Mean −− 126.3 −− 185.8 −− 420.1
SD
CV
1 −−
−−
2.42
1.9
2 −−
−−
2.98
1.6
3 −−
−−
5.23
1.2
# Points −− 455 −− 455 −− 629
# Labs 2 2 2
Mean −− 121.8 −− 180.4 −− 394.9
SD
CV
1 −−
−−
4.73
3.9
2 −−
−−
5.96
3.3
3 −−
−−
14.13
3.6
# Points −− 273 −− 264 −− 264
# Labs 1 1 1

Mean −− 120.6 −− −− −− 398.5
SD
CV
1 −−
−−
3.50
2.9
2 −−
−−
−−
−−
3 −−
−−
7.17
1.8
# Points −− 278 −− −− −− 278
# Labs 1 1

Mean 122.2 122.3 176.5 181.4 412.6 412.9
SD
CV
1 2.51
2.1
3.23
2.6
2 3.60
2.0
5.74
3.2
3 7.15
1.7
10.47
2.5
# Points 86 4132 22 3416 87 4152
# Labs 3 13 1 12 3 12

Mean −− 121.0 −− 181.7 −− 403.4
SD
CV
1 −−
−−
3.30
2.7
2 −−
−−
5.51
3.0
3 −−
−−
10.07
2.5
# Points −− 1825 −− 125 −− 1763
# Labs 5 4 4

Mean 117.2 116.3 167.7 173.7 395.9 395.6
SD
CV
1 6.96
5.9
6.07
5.2
2 3.50
2.1
6.59
3.8
3 12.27
3.1
12.61
3.2
# Points 116 11672 9 1776 119 9889
# Labs 6 26 2 4 6 24

Mean 118.9 118.3 177.1 175.2 395.2 394.9
SD
CV
1 4.48
3.8
4.72
4.0
2 4.82
2.7
5.73
3.3
3 9.09
2.3
9.77
2.5
# Points 683 31756 110 10609 478 25262
# Labs 17 55 3 20 14 49

Mean −− 102.1 −− 150.1 −− 330.0
SD
CV
1 −−
−−
2.15
2.1
2 −−
−−
2.85
1.9
3 −−
−−
5.40
1.6
# Points −− 107 −− 107 −− 107
# Labs 1 1 1
Toshiba−TBA
Mean −− −− −− −− −− 424.0
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
8.54
2.0
# Points −− −− −− −− −− 80
# Labs 1

Mean −− 111.2 −− 168.4 −− 389.6
SD
CV
1 −−
−−
2.82
2.5
2 −−
−−
3.47
2.1
3 −−
−−
5.81
1.5
# Points −− 455 −− 456 −− 476
# Labs 3 3 3

Mean −− 126.3 −− −− −− 418.4
SD
CV
1 −−
−−
2.58
2.0
2 −−
−−
−−
−−
3 −−
−−
5.20
1.2
# Points −− 61 −− −− −− 61
# Labs 1 1

Mean 125.2 125.5 174.8 174.8 431.0 432.1
SD
CV
1 4.78
3.8
3.31
2.6
2 1.35
0.8
1.35
0.8
3 15.65
3.6
10.48
2.4
# Points 28 82 5 5 27 82
# Labs 2 2 1 1 2 2

Mean 108.5 112.8 156.1 169.1 379.3 381.1
SD
CV
1 11.77
10.9
11.32
10.0
2 16.34
10.5
16.68
9.9
3 34.36
9.1
36.64
9.6
# Points 3253 162K 2074 93204 1940 145K
# Labs 109 459 76 292 71 403
LD (Lactate Dehydrogenase) Lactate to pyruvate U/L

Mean 118.7 118.6 174.6 175.5 −− −−
SD
CV
1 2.57
2.2
2.38
2.0
2 3.21
1.8
2.80
1.6
3 −−
−−
−−
−−
# Points 25 47 25 46 −− −−
# Labs 1 1 1 1

Mean 203.0 234.4 352.0 365.3 −− 970.0
SD
CV
1 29.67
14.6
35.25
15.0
2 37.19
10.6
43.82
12.0
3 −−
−−
0.000
0.0
# Points 24 107 12 103 −− 1
# Labs 1 1 1 1 1
RANDOX RX imola
Mean 96.81 97.00 153.5 152.8 −− −−
SD
CV
1 4.60
4.8
7.58
7.8
2 4.91
3.2
11.27
7.4
3 −−
−−
−−
−−
# Points 26 224 24 194 −− −−
# Labs 1 1 1 1

Mean −− 123.5 −− −− −− 410.1
SD
CV
1 −−
−−
4.22
3.4
2 −−
−−
−−
−−
3 −−
−−
7.06
1.7
# Points −− 169 −− −− −− 160
# Labs 4 4

Mean 138.1 133.9 201.2 219.6 −− 413.6
SD
CV
1 48.72
35.3
53.49
39.9
2 77.59
38.6
99.14
45.1
3 −−
−−
44.68
10.8
# Points 75 547 61 343 −− 161
# Labs 3 7 3 3 5
LD (Lactate Dehydrogenase) Pyruvate to lactate U/L @ 25° C

Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c Uric2, REF 04U09
Mean 129.8 122.2 192.4 182.7 −− −−
SD
CV
1 4.13
3.2
6.61
5.4
2 4.71
2.4
7.98
4.4
3 −−
−−
−−
−−
# Points 26 189 26 187 −− −−
# Labs 1 1 1 1
ILab Series
Mean 177.1 192.4 302.9 313.6 −− −−
SD
CV
1 12.41
7.0
17.46
9.1
2 8.18
2.7
13.84
4.4
3 −−
−−
−−
−−
# Points 11 48 11 48 −− −−
# Labs 1 1 1 1
Method Group • Pyruvate to lactate

Mean 143.8 136.4 225.3 209.4 −− −−
SD
CV
1 23.14
16.1
29.90
21.9
2 51.51
22.9
53.74
25.7
3 −−
−−
−−
−−
# Points 37 237 37 235 −− −−
# Labs 2 2 2 2

Mean −− 114.1 −− −− −− 384.5
SD
CV
1 −−
−−
5.85
5.1
2 −−
−−
−−
−−
3 −−
−−
6.51
1.7
# Points −− 57 −− −− −− 58
# Labs 1 1

Mean −− 244.2 −− 173.1 −− 874.2
SD
CV
1 −−
−−
23.15
9.5
2 −−
−−
8.04
4.6
3 −−
−−
85.66
9.8
# Points −− 709 −− 2801 −− 709
# Labs 4 9 4

Mean −− 128.6 −− −− −− 445.3
SD
CV
1 −−
−−
3.34
2.6
2 −−
−−
−−
−−
3 −−
−−
7.92
1.8
# Points −− 145 −− −− −− 143
# Labs 1 1

Mean −− 119.0 −− −− −− −−
SD
CV
1 −−
−−
4.77
4.0
2
−−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 78 −− −− −− −−
# Labs 1

Mean 229.2 243.0 344.3 345.0 841.0 764.3
SD
CV
1 31.21
13.6
16.91
7.0
2 23.63
6.9
17.43
5.1
3 33.56
4.0
42.81
5.6
# Points 30 393 27 318 5 43
# Labs 2 2 2 2 1 1
ERBA XL−640
Mean −− 252.5 −− 368.8 −− −−
SD
CV
1 −−
−−
7.99
3.2
2 −−
−−
13.82
3.7
3 −−
−−
−−
−−
# Points −− 59 −− 59 −− −−
# Labs 1 1
RANDOX RX daytona
Mean 178.6 197.3 305.8 298.9 780.0 780.0
SD
CV
1 22.15
12.4
27.32
13.8
2 15.02
4.9
31.54
10.6
3 0.000
0.0
0.000
0.0
# Points 20 87 16 88 1 1
# Labs 1 1 1 1 1 1

Mean −− 120.5 −− −− −− 407.7
SD
CV
1 −−
−−
2.90
2.4
2 −−
−−
−−
−−
3 −−
−−
8.00
2.0
# Points −− 246 −− −− −− 256
# Labs 1 1

Mean −− 125.7 −− 186.4 −− 426.1
SD
CV
1 −−
−−
5.63
4.5
2 −−
−−
9.39
5.0
3 −−
−−
15.57
3.7
# Points −− 252 −− 252 −− 252
# Labs 2 2 2
Mean −− −− −− 172.8 −− 394.9
SD
CV
1 −−
−−
−−
−−
2 −−
−−
3.26
1.9
3 −−
−−
6.15
1.6
# Points −− −− −− 288 −− 284
# Labs 1 1

Mean −− 250.1 −− 366.8 −− 862.5
SD
CV
1 −−
−−
5.70
2.3
2 −−
−−
8.69
2.4
3 −−
−−
17.62
2.0
# Points −− 7028 −− 5277 −− 7023
# Labs 10 7 10

Mean −− 119.2 −− −− −− 398.1
SD
CV
1 −−
−−
2.85
2.4
2 −−
−−
−−
−−
3 −−
−−
7.96
2.0
# Points −− 468 −− −− −− 475
# Labs 1 1

Mean −− −− 190.5 191.1 408.6 414.6
SD
CV
1 −−
−−
−−
−−
2 5.63
3.0
6.03
3.2
3 7.96
1.9
15.11
3.6
# Points −− −− 32 347 31 333
# Labs 1 1 1 1

Mean 208.9 232.1 270.5 290.7 477.1 777.5
SD
CV
1 37.32
17.9
44.25
19.1
2 72.67
26.9
93.03
32.0
3 158.6
33.2
180.0
23.1
# Points 50 9527 75 9435 37 9582
# Labs 3 25 4 24 3 24

Toshiba−TBA
Mean 115.0 117.8 −− −− 386.0 391.3
SD
CV
1 1.41
1.2
1.07
0.9
2 −−
−−
−−
−−
3 0.000
0.0
2.60
0.7
# Points 2 362 −− −− 1 361
# Labs 1 1 1 1

Mean 115.0 117.8 −− −− 386.0 391.3
SD
CV
1 1.41
1.2
1.07
0.9
2 −−
−−
−−
−−
3 0.000
0.0
2.60
0.7
# Points 2 362 −− −− 1 361
# Labs 1 1 1 1
LD (Lactate Dehydrogenase) Pyruvate to lactate−VITROS U/L @ 37° C

Mean −− 232.4 507.4 388.0 −− 944.1
SD
CV
1 −−
−−
67.78
29.2
2 17.85
3.5
147.7
38.1
3 −−
−−
38.04
4.0
# Points −− 748 17 1152 −− 546
# Labs 9 1 10 3

Mean −− 290.2 −− 435.4 −− 971.5
SD
CV
1 −−
−−
11.73
4.0
2 −−
−−
14.81
3.4
3 −−
−−
34.29
3.5
# Points −− 4011 −− 1799 −− 3715
# Labs 23 11 20

Mean −− 293.2 −− 444.5 −− 988.0
SD
CV
1 −−
−−
14.06
4.8
2 −−
−−
21.40
4.8
3 −−
−−
33.36
3.4
# Points −− 1084 −− 836 −− 591
# Labs 8 5 6
LD (Lactate Dehydrogenase) Pyruvate to lactate−VITROS U/L @ 37° C

Mean −− 289.4 −− 436.9 −− 996.5
SD
CV
1 −−
−−
14.28
4.9
2 −−
−−
20.42
4.7
3 −−
−−
31.62
3.2
# Points −− 2898 −− 2136 −− 2518
# Labs 16 12 11

Mean −− 281.3 −− 399.3 −− 994.6
SD
CV
1 −−
−−
17.93
6.4
2 −−
−−
19.18
4.8
3 −−
−−
27.82
2.8
# Points −− 1034 −− 439 −− 994
# Labs 3 1 3

Mean −− 117.4 −− −− −− 404.8
SD
CV
1 −−
−−
4.69
4.0
2 −−
−−
−−
−−
3 −−
−−
13.28
3.3
# Points −− 425 −− −− −− 412
# Labs 1 1

Mean −− 119.6 −− −− −− 413.7
SD
CV
1 −−
−−
3.70
3.1
2 −−
−−
−−
−−
3 −−
−−
9.60
2.3
# Points −− 632 −− −− −− 630
# Labs 1 1

Mean 122.7 123.7 −− 183.5 405.3 395.9
SD
CV
1 2.98
2.4
4.26
3.4
2 −−
−−
5.09
2.8
3 5.70
1.4
13.17
3.3
# Points 22 2617 −− 748 22 2725
# Labs 1 38 16 1 35

Mean 122.0 124.3 175.8 187.8 390.8 406.6
SD
CV
1 6.69
5.5
6.45
5.2
2 3.93
2.2
8.14
4.3
3 8.63
2.2
17.04
4.2
# Points 137 2954 25 1831 111 2564
# Labs 5 20 1 12 4 14

Mean 124.0 124.9 181.4 184.1 413.7 405.9
SD
CV
1 3.66
2.9
3.73
3.0
2 5.14
2.8
6.64
3.6
3 7.89
1.9
19.38
4.8
# Points 118 1078 66 482 48 624
# Labs 6 9 4 5 2 5

Mean 132.3 132.9 195.3 195.8 433.6 431.0
SD
CV
1 2.68
2.0
4.48
3.4
2 4.79
2.5
6.05
3.1
3 5.91
1.4
6.87
1.6
# Points 35 77 36 78 36 77
# Labs 4 4 4 4 4 4
Method Group • Pyruvate to lactate−VITROS

Mean 124.0 213.6 222.4 347.5 404.4 718.3
SD
CV
1 5.97
4.8
82.83
38.8
2 105.1
47.3
125.7
36.2
3 17.78
4.4
289.1
40.3
# Points 312 17608 144 9466 217 15474
# Labs 16 133 10 75 11 104
LD (Lactate Dehydrogenase) Tetrazolium U/L @ 37° C

Mean −− 275.1 −− 421.6 −− 986.3
SD
CV
1 −−
−−
5.82
2.1
2 −−
−−
6.53
1.5
3 −−
−−
12.43
1.3
# Points −− 89 −− 89 −− 87
# Labs 1 1 1
LD (Lactate Dehydrogenase) Tetrazolium U/L @ 37° C

Method Group • Tetrazolium
Mean −− 275.1 −− 421.6 −− 986.3
SD
CV
1 −−
−−
5.82
2.1
2 −−
−−
6.53
1.5
3 −−
−−
12.43
1.3
# Points −− 89 −− 89 −− 87
# Labs 1 1 1
Lipase Chemiluminescence U/dL @ 25° C

Mean −− 99.84 −− 4.97 −− 1194
SD
CV
1 −−
−−
6.48
6.5
2 −−
−−
0.032
0.6
3 −−
−−
106.7
8.9
# Points −− 325 −− 2 −− 323
# Labs 2 1 2

Mean −− 99.84 −− 4.97 −− 1194
SD
CV
1 −−
−−
6.48
6.5
2 −−
−−
0.032
0.6
3 −−
−−
106.7
8.9
# Points −− 325 −− 2 −− 323
# Labs 2 1 2

Mean −− 1.97 −− −− −− 15.11
SD
CV
1 −−
−−
0.194
9.8
2 −−
−−
−−
−−
3 −−
−−
0.948
6.3
# Points −− 121 −− −− −− 155
# Labs 1 1

Mean −− −− 3.93 4.17 13.39 13.82
SD
CV
1 −−
−−
−−
−−
2 0.168
4.3
0.278
6.7
3 0.408
3.0
0.622
4.5
# Points −− −− 18 219 18 220
# Labs 1 1 1 1

Mean −− 2.00 −− −− −− 17.00
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− 1 −− −− −− 1
# Labs 1 1
Siemens Dimension Series • Siemens Dimension LIP REF DF56A

Mean −− 2.18 −− −− −− 15.79
SD
CV
1 −−
−−
0.138
6.3
−−
−−
2 −−
−−
3 −−
−−
0.675
4.3
# Points −− 216 −− −− −− 219
# Labs 1 1

Mean −− 2.11 3.93 4.17 13.39 14.88
SD
CV
1 −−
−−
0.190
9.0
2 0.168
4.3
0.278
6.7
3 0.408
3.0
1.13
7.6
# Points −− 338 18 219 18 595
# Labs 3 1 1 1 4

Mean −− 1.77 −− −− −− 22.21
SD
CV
1 −−
−−
0.076
4.3
2 −−
−−
−−
−−
3 −−
−−
0.952
4.3
# Points −− 407 −− −− −− 383
# Labs 2 2

Mean −− 1.77 −− −− −− 22.21
SD
CV
1 −−
−−
0.076
4.3
2 −−
−−
−−
−−
3 −−
−−
0.952
4.3
# Points −− 407 −− −− −− 383
# Labs 2 2
Lipase Chemiluminescence U/L @ 25° C

Mean −− 998.4 −− 49.70 −− 11942
SD
CV
1 −−
−−
64.83
6.5
2 −−
−−
0.320
0.6
3 −−
−−
1067
8.9
# Points −− 325 −− 2 −− 323
# Labs 2 1 2

Mean −− 998.4 −− 49.70 −− 11942
SD
CV
1 −−
−−
64.83
6.5
2 −−
−−
0.320
0.6
3 −−
−−
1067
8.9
# Points −− 325 −− 2 −− 323
# Labs 2 1 2

Mean −− 19.72 −− −− −− 151.1
SD
CV
1 −−
−−
1.94
9.8
2 −−
−−
−−
−−
3 −−
−−
9.48
6.3
# Points −− 121 −− −− −− 155
# Labs 1 1

Mean −− −− 39.33 41.70 133.9 138.2
SD
CV
1 −−
−−
−−
−−
2 1.68
4.3
2.78
6.7
3 4.08
3.0
6.22
4.5
# Points −− −− 18 219 18 220
# Labs 1 1 1 1

Mean −− 20.00 −− −− −− 170.0
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− 1 −− −− −− 1
# Labs 1 1

Mean −− 21.84 −− −− −− 157.9
SD
CV
1 −−
−−
1.38
6.3
−−
−−
2 −−
−−
3 −−
−−
6.75
4.3
# Points −− 216 −− −− −− 219
# Labs 1 1

Mean −− 21.08 39.33 41.70 133.9 148.8
SD
CV
1 −−
−−
1.90
9.0
2 1.68
4.3
2.78
6.7
3 4.08
3.0
11.33
7.6
# Points −− 338 18 219 18 595
# Labs 3 1 1 1 4

Mean −− 17.68 −− −− −− 222.1
SD
CV
1 −−
−−
0.756
4.3
2 −−
−−
−−
−−
3 −−
−−
9.52
4.3
# Points −− 407 −− −− −− 383
# Labs 2 2

Mean −− 17.68 −− −− −− 222.1
SD
CV
1 −−
−−
0.756
4.3
2 −−
−−
−−
−−
3 −−
−−
9.52
4.3
# Points −− 407 −− −− −− 383
# Labs 2 2
Lipase Colorimetric U/dL @ 25° C

Abbott ARCHITECT/Alinity (c, i, ci models) • Sentinel Lipase REF 04Y85
Mean −− 1.73 −− −− −− 20.23
SD
CV
1 −−
−−
0.202
11.7
2 −−
−−
−−
−−
3 −−
−−
1.15
5.7
# Points −− 60 −− −− −− 283
# Labs 2 2

Mean −− 1.62 −− 5.06 −− 19.19
SD
CV
1 −−
−−
0.031
1.9
2 −−
−−
0.084
1.7
3 −−
−−
0.387
2.0
# Points −− 43 −− 43 −− 43
# Labs 1 1 1

Mean −− 2.39 −− −− −− 14.05
SD
CV
1 −−
−−
0.183
7.7
2 −−
−−
−−
−−
3 −−
−−
0.938
6.7
# Points −− 164 −− −− −− 162
# Labs 1 1

Mean 2.10 2.16 −− −− 15.31 15.81
SD
CV
1 0.056
2.7
0.090
4.2
2 −−
−−
−−
−−
3 0.186
1.2
0.523
3.3
# Points 42 669 −− −− 42 664
# Labs 2 2 2 2

Mean 2.10 2.15 −− 5.06 15.31 16.77
SD
CV
1 0.056
2.7
0.221
10.3
2 −−
−−
0.084
1.7
3 0.186
1.2
2.31
13.8
# Points 42 936 −− 43 42 1152
# Labs 2 6 1 2 6

Mean 1.74 1.84 4.29 4.40 −− 13.49
SD
CV
1 0.113
6.5
0.104
5.7
2 0.152
3.5
0.167
3.8
3 −−
−−
0.504
3.7
# Points 16 538 16 121 −− 398
# Labs 1 4 1 1 2

Mean 1.69 2.09 4.78 4.59 −− 20.23
SD
CV
1 0.030
1.8
0.292
14.0
20.452
9.5
0.397
8.6
3 −−
−−
0.891
4.4
# Points 15 234 15 55 −− 185
# Labs 1 2 1 1 1

Mean 1.64 1.70 4.34 4.41 14.61 14.67
SD
CV
1 0.126
7.7
0.153
9.0
2 0.158
3.6
0.240
5.4
3 0.419
2.9
0.535
3.6
# Points 127 6307 129 4751 125 6066
# Labs 3 12 3 8 3 12

Mean 2.57 2.42 −− 5.04 14.50 14.30
SD
CV
1 0.110
4.3
0.187
7.7
2 −−
−−
0.344
6.8
3 0.674
4.6
1.22
8.5
# Points 66 8045 −− 2123 65 7979
# Labs 2 30 10 2 26
ERBA XL−640
Mean −− 2.76 −− 4.75 −− −−
SD
CV
1 −−
−−
0.246
8.9
2 −−
−−
0.279
5.9
3 −−
−−
−−
−−
# Points −− 57 −− 57 −− −−
# Labs 1 1

Mean −− 1.97 −− 7.12 −− 27.64
SD
CV
1 −−
−−
0.164
8.3
2 −−
−−
0.461
6.5
3 −−
−−
1.73
6.3
# Points −− 2640 −− 2591 −− 2514
# Labs 6 6 6
RANDOX RX daytona
Mean 2.10 2.25 5.50 5.82 15.67 15.99
SD
CV
1 0.284
13.5
0.352
15.7
2 0.493
9.0
0.717
12.3
3 1.15
7.3
0.756
4.7
# Points 89 647 69 577 6 45
# Labs 4 4 4 4 2 3
RANDOX RX imola
Mean −− −− −− 5.81 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.347
6.0
3 −−
−−
−−
−−
# Points −− −− −− 64 −− −−
# Labs 1

Mean −− 2.02 −− 5.00 −− 16.72
SD
CV
1 −−
−−
0.050
2.5
2 −−
−−
0.097
1.9
3 −−
−−
0.255
1.5
# Points −− 2193 −− 40 −− 2185
# Labs 3 1 3
Roche cobas 6000/8000/c 311 • Roche Lipase ACN 789/8789/786/8786 high

Mean −− 1.96 −− −− −− 17.69
SD
CV
1 −−
−−
0.075
3.8
−−
−−
2 −−
−−
3 −−
−−
0.347
2.0
# Points −− 355 −− −− −− 357
# Labs 1 1

Mean −− 2.07 −− 4.75 −− 15.55
SD
CV
1 −−
−−
0.089
4.3
2 −−
−−
0.145
3.1
3 −−
−−
0.528
3.4
# Points −− 582 −− 908 −− 494
# Labs 1 1 1

Mean 1.95 1.92 5.12 5.01 18.41 17.77
SD
CV
1 0.092
4.7
0.065
3.4
2 0.142
2.8
0.139
2.8
3 0.298
1.6
0.581
3.3
# Points 14 271 14 271 14 271
# Labs 1 1 1 1 1 1

Mean −− 2.60 −− −− −− 19.84
SD
CV
1 −−
−−
0.092
3.5
2 −−
−−
−−
−−
3 −−
−−
0.495
2.5
# Points −− 212 −− −− −− 212
# Labs 1 1

Mean 2.05 3.36 −− 12.75 15.21 27.22
SD
CV
1 0.070
3.4
1.62
48.2
2 −−
−−
2.56
20.1
3 0.253
1.7
11.24
41.3
# Points 32 1870 −− 997 32 1738
# Labs 1 6 2 1 5

Mean −− 8.25 −− 4.99 −− 56.49
SD
CV
1 −−
−−
0.290
3.5
−−
−−
2 0.086
1.7
3 −−
−−
1.03
1.8
# Points −− 366 −− 54 −− 367
# Labs 1 1 1

Mean 1.98 2.27 4.74 5.85 14.75 17.97
SD
CV
1 0.380
19.2
0.987
43.4
2 0.605
12.8
2.40
41.1
3 1.15
7.8
7.72
43.0
# Points 359 24374 243 12570 264 22833
# Labs 13 74 10 38 10 64
Lipase Colorimetric U/L @ 25° C

Mean −− 17.27 −− −− −− 202.3
SD
CV
1 −−
−−
2.02
11.7
2 −−
−−
−−
−−
3 −−
−−
11.48
5.7
# Points −− 60 −− −− −− 283
# Labs 2 2

Mean −− 16.16 −− 50.57 −− 191.9
SD
CV
1 −−
−−
0.313
1.9
2 −−
−−
0.843
1.7
3 −−
−−
3.87
2.0
# Points −− 43 −− 43 −− 43
# Labs 1 1 1

Mean −− 23.86 −− −− −− 140.5
SD
CV
1 −−
−−
1.83
7.7
2 −−
−−
−−
−−
3 −−
−−
9.38
6.7
# Points −− 164 −− −− −− 162
# Labs 1 1

Mean 21.05 21.63 −− −− 153.1 158.1
SD
CV
1 0.564
2.7
0.900
4.2
2 −−
−−
−−
−−
3 1.86
1.2
5.23
3.3
# Points 42 669 −− −− 42 664
# Labs 2 2 2 2

Mean 21.05 21.49 −− 50.57 153.1 167.7
SD
CV
1 0.564
2.7
2.21
10.3
2 −−
−−
0.843
1.7
3 1.86
1.2
23.12
13.8
# Points 42 936 −− 43 42 1152
# Labs 2 6 1 2 6

Mean 17.35 18.42 42.91 44.04 −− 134.9
SD
CV
1 1.13
6.5
1.04
5.7
2 1.52
3.5
1.67
3.8
3 −−
−−
5.04
3.7
# Points 16 538 16 121 −− 398
# Labs 1 4 1 1 2

Mean 16.90 20.92 47.75 45.94 −− 202.3
SD
CV
1 0.301
1.8
2.92
14.0
2
4.52
9.5
3.97
8.6
3 −−
−−
8.91
4.4
# Points 15 234 15 55 −− 185
# Labs 1 2 1 1 1

Mean 16.43 16.99 43.39 44.07 146.1 146.7
SD
CV
1 1.26
7.7
1.53
9.0
2 1.58
3.6
2.40
5.4
3 4.19
2.9
5.35
3.6
# Points 127 6307 129 4751 125 6066
# Labs 3 12 3 8 3 12

Mean 25.73 24.25 −− 50.44 145.0 143.0
SD
CV
1 1.10
4.3
1.87
7.7
2 −−
−−
3.44
6.8
3 6.74
4.6
12.16
8.5
# Points 66 8045 −− 2123 65 7979
# Labs 2 30 10 2 26
ERBA XL−640
Mean −− 27.58 −− 47.48 −− −−
SD
CV
1 −−
−−
2.46
8.9
2 −−
−−
2.79
5.9
3 −−
−−
−−
−−
# Points −− 57 −− 57 −− −−
# Labs 1 1

Mean −− 19.72 −− 71.21 −− 276.4
SD
CV
1 −−
−−
1.64
8.3
2 −−
−−
4.61
6.5
3 −−
−−
17.34
6.3
# Points −− 2640 −− 2591 −− 2514
# Labs 6 6 6
RANDOX RX daytona
Mean 21.04 22.47 54.96 58.17 156.7 159.9
SD
CV
1 2.84
13.5
3.52
15.7
2 4.93
9.0
7.17
12.3
3 11.48
7.3
7.56
4.7
# Points 89 647 69 577 6 45
# Labs 4 4 4 4 2 3
RANDOX RX imola
Mean −− −− −− 58.08 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
3.47
6.0
3 −−
−−
−−
−−
# Points −− −− −− 64 −− −−
# Labs 1

Mean −− 20.18 −− 49.98 −− 167.2
SD
CV
1 −−
−−
0.501
2.5
2 −−
−−
0.974
1.9
3 −−
−−
2.55
1.5
# Points −− 2193 −− 40 −− 2185
# Labs 3 1 3

Mean −− 19.63 −− −− −− 176.9
SD
CV
1 −−
−−
0.750
3.8
−−
−−
2 −−
−−
3 −−
−−
3.47
2.0
# Points −− 355 −− −− −− 357
# Labs 1 1

Mean −− 20.68 −− 47.45 −− 155.5
SD
CV
1 −−
−−
0.888
4.3
2 −−
−−
1.45
3.1
3 −−
−−
5.28
3.4
# Points −− 582 −− 908 −− 494
# Labs 1 1 1

Mean 19.54 19.23 51.19 50.11 184.1 177.7
SD
CV
1 0.920
4.7
0.650
3.4
2 1.42
2.8
1.39
2.8
3 2.98
1.6
5.81
3.3
# Points 14 271 14 271 14 271
# Labs 1 1 1 1 1 1

Mean −− 26.04 −− −− −− 198.4
SD
CV
1 −−
−−
0.918
3.5
2 −−
−−
−−
−−
3 −−
−−
4.95
2.5
# Points −− 212 −− −− −− 212
# Labs 1 1

Mean 20.46 33.63 −− 127.5 152.1 272.2
SD
CV
1 0.699
3.4
16.22
48.2
2 −−
−−
25.63
20.1
3 2.53
1.7
112.4
41.3
# Points 32 1870 −− 997 32 1738
# Labs 1 6 2 1 5

Mean −− 82.47 −− 49.89 −− 564.9
SD
CV
1 −−
−−
2.90
3.5
−−
−−
2 0.862
1.7
3 −−
−−
10.30
1.8
# Points −− 366 −− 54 −− 367
# Labs 1 1 1

Mean 19.83 22.72 47.36 58.50 147.5 179.7
SD
CV
1 3.80
19.2
9.87
43.4
2 6.05
12.8
24.04
41.1
3 11.49
7.8
77.19
43.0
# Points 359 24374 243 12570 264 22833
# Labs 13 74 10 38 10 64
Lipase Colorimetric (Siemens calibrated) U/dL @ 25° C

Mean −− 2.35 −− 5.79 −− 19.50
SD
CV
1 −−
−−
0.238
10.1
2 −−
−−
0.281
4.8
3 −−
−−
0.647
3.3
# Points −− 1380 −− 1377 −− 1364
# Labs 2 2 2
Method Group • Colorimetric (Siemens calibrated)

Mean −− 3.27 −− 5.79 −− 28.42
SD
CV
1 −−
−−
1.96
59.8
2 −−
−−
0.281
4.8
3 −−
−−
18.32
64.5
# Points −− 1820 −− 1377 −− 1823
# Labs 3 2 3

Mean −− 2.35 −− 5.93 −− 20.32
SD
CV
1 −−
−−
0.136
5.8
2 −−
−−
0.234
3.9
3 −−
−−
0.733
3.6
# Points −− 1236 −− 669 −− 1233
# Labs 3 3 3

Mean −− 2.42 −− −− −− 19.95
SD
CV
1 −−
−−
0.184
7.6
2 −−
−−
−−
−−
3 −−
−−
0.955
4.8
# Points −− 2312 −− −− −− 2280
# Labs 5 5

Mean −− 6.15 −− 14.45 −− 47.96
SD
CV
1 −−
−−
0.540
8.8
2 −−
−−
0.675
4.7
3 −−
−−
1.99
4.2
# Points −− 14023 −− 3796 −− 11424
# Labs 44 12 37

Mean 2.10 2.16 4.82 4.90 14.94 15.59
SD
CV
1 0.103
4.9
0.222
10.3
0.138
2.9
2 0.207
4.2
3 1.61
10.8
1.94
12.5
# Points 1093 15749 275 3968 995 14887
# Labs 34 84 9 17 31 76
Siemens Dimension Series • Siemens Dimension LIPL (DF56)

Mean 4.45 6.14 −− 14.41 −− 47.92
SD
CV
1 0.667
15.0
0.651
10.6
2 −−
−−
0.869
6.0
3 −−
−−
1.98
4.1
# Points 34 43099 −− 6858 −− 40967
# Labs 1 135 30 123

Mean 6.67 7.22 19.02 18.92 67.60 66.78
SD
CV
1 0.495
7.4
0.837
11.6
2 0.778
4.1
1.46
7.7
3 3.71
5.5
4.19
6.3
# Points 341 160K 170 42021 246 151K
# Labs 12 380 6 104 9 361
Siemens Dimension Vista • Alternate Calibration

Mean −− 6.70 −− 17.42 −− 64.55
SD
CV
1 −−
−−
0.902
13.5
2 −−
−−
0.673
3.9
3 −−
−−
4.17
6.5
# Points −− 3705 −− 1198 −− 3734
# Labs 22 9 22
Siemens Dimension Vista • Siemens Dimension LIP REF DF56A

Mean −− 6.84 −− −− −− −−
SD
CV
1 −−
−−
0.399
5.8
−−
−−
2 −−
−−
3 −−
−−
−−
−−
# Points −− 300 −− −− −− −−
# Labs 2
Siemens Dimension Vista • Siemens Dimension Vista LIP REF K3056A

Mean 2.09 2.14 4.59 4.71 14.53 15.00
SD
CV
1 0.123
5.9
0.147
6.8
0.184
4.0
2 0.209
4.4
3 0.403
2.8
0.640
4.3
# Points 1793 27761 632 10435 1587 24903
# Labs 56 127 23 36 50 123
Siemens Dimension Vista • Siemens Dimension Vista LIPL REF K3056

Mean −− 7.24 −− 18.67 −− 66.89
SD
CV
1 −−
−−
0.735
10.2
−−
−−
2 1.55
8.3
3 −−
−−
3.78
5.7
# Points −− 9599 −− 3442 −− 9265
# Labs 27 9 28

Mean 2.55 6.09 6.71 15.10 19.29 55.40
SD
CV
1 1.41
55.1
2.19
35.9
2 5.04
75.2
6.26
41.4
3 14.99
77.7
20.87
37.7
# Points 3339 242K 1189 74211 2828 216K
# Labs 105 686 41 193 90 635

Mean 2.10 2.06 −− −− 16.02 15.73
SD
CV
1 0.083
4.0
0.096
4.7
2 −−
−−
−−
−−
3 0.503
3.1
0.443
2.8
# Points 33 98 −− −− 33 99
# Labs 1 1 1 1

Mean 2.10 2.06 −− −− 16.02 15.73
SD
CV
1 0.083
4.0
0.096
4.7
2 −−
−−
−−
−−
3 0.503
3.1
0.443
2.8
# Points 33 98 −− −− 33 99
# Labs 1 1 1 1
Lipase Colorimetric (Siemens calibrated) U/L @ 25° C

Mean −− 23.51 −− 57.94 −− 195.0
SD
CV
1 −−
−−
2.38
10.1
2 −−
−−
2.81
4.8
3 −−
−−
6.47
3.3
# Points −− 1380 −− 1377 −− 1364
# Labs 2 2 2

Mean −− 32.74 −− 57.94 −− 284.2
SD
CV
1 −−
−−
19.59
59.8
2 −−
−−
2.81
4.8
3 −−
−−
183.2
64.5
# Points −− 1820 −− 1377 −− 1823
# Labs 3 2 3

Mean −− 23.48 −− 59.26 −− 203.2
SD
CV
1 −−
−−
1.36
5.8
2 −−
−−
2.34
3.9
3 −−
−−
7.33
3.6
# Points −− 1236 −− 669 −− 1233
# Labs 3 3 3

Mean −− 24.19 −− −− −− 199.5
SD
CV
1 −−
−−
1.84
7.6
2 −−
−−
−−
−−
3 −−
−−
9.55
4.8
# Points −− 2312 −− −− −− 2280
# Labs 5 5

Mean −− 61.53 −− 144.5 −− 479.6
SD
CV
1 −−
−−
5.40
8.8
2 −−
−−
6.75
4.7
3 −−
−−
19.91
4.2
# Points −− 14023 −− 3796 −− 11424
# Labs 44 12 37

Mean 21.00 21.61 48.25 48.99 149.4 155.9
SD
CV
1 1.03
4.9
2.22
10.3
2
1.38
2.9
2.07
4.2
3 16.09
10.8
19.42
12.5
# Points 1093 15749 275 3968 995 14887
# Labs 34 84 9 17 31 76
Siemens Dimension Series • Siemens Dimension LIPL (DF56)

Mean 44.53 61.37 −− 144.1 −− 479.2
SD
CV
1 6.67
15.0
6.51
10.6
2 −−
−−
8.69
6.0
3 −−
−−
19.76
4.1
# Points 34 43099 −− 6858 −− 40967
# Labs 1 135 30 123

Mean 66.72 72.21 190.2 189.2 676.0 667.8
SD
CV
1 4.95
7.4
8.37
11.6
2 7.78
4.1
14.63
7.7
3 37.11
5.5
41.90
6.3
# Points 341 160K 170 42021 246 151K
# Labs 12 380 6 104 9 361

Siemens Dimension Vista • Alternate Calibration
Mean −− 67.04 −− 174.2 −− 645.5
SD
CV
1 −−
−−
9.02
13.5
2 −−
−−
6.73
3.9
3 −−
−−
41.69
6.5
# Points −− 3705 −− 1198 −− 3734
# Labs 22 9 22
Siemens Dimension Vista • Siemens Dimension LIP REF DF56A

Mean −− 68.39 −− −− −− −−
SD
CV
1 −−
−−
3.99
5.8
−−
−−
2 −−
−−
3 −−
−−
−−
−−
# Points −− 300 −− −− −− −−
# Labs 2
Siemens Dimension Vista • Siemens Dimension Vista LIP REF K3056A

Mean 20.88 21.44 45.87 47.14 145.3 150.0
SD
CV
1 1.23
5.9
1.47
6.8
1.84
4.0
2 2.09
4.4
3 4.03
2.8
6.40
4.3
# Points 1793 27761 632 10435 1587 24903
# Labs 56 127 23 36 50 123
Siemens Dimension Vista • Siemens Dimension Vista LIPL REF K3056

Mean −− 72.41 −− 186.7 −− 668.9
SD
CV
1 −−
−−
7.35
10.2
−−
−−
215.52
8.3
3 −−
−−
37.84
5.7
# Points −− 9599 −− 3442 −− 9265
# Labs 27 9 28

Mean 25.50 60.89 67.07 151.0 192.9 554.0
SD
CV
1 14.05
55.1
21.89
35.9
2 50.45
75.2
62.57
41.4
3 149.9
77.7
208.7
37.7
# Points 3339 242K 1189 74211 2828 216K
# Labs 105 686 41 193 90 635

Mean 21.00 20.63 −− −− 160.2 157.3
SD
CV
1 0.830
4.0
0.963
4.7
2 −−
−−
−−
−−
3 5.03
3.1
4.43
2.8
# Points 33 98 −− −− 33 99
# Labs 1 1 1 1

Mean 21.00 20.63 −− −− 160.2 157.3
SD
CV
1 0.830
4.0
0.963
4.7
2 −−
−−
−−
−−
3 5.03
3.1
4.43
2.8
# Points 33 98 −− −− 33 99
# Labs 1 1 1 1
Lipase Coupled enzymatic U/dL @ 37° C

Mean −− 2.22 −− 5.83 −− 20.25
SD
CV
1 −−
−−
0.099
4.5
2 −−
−−
0.237
4.1
3 −−
−−
0.753
3.7
# Points −− 247 −− 494 −− 405
# Labs 3 3 3
Method Group • Coupled enzymatic

Mean −− 2.22 −− 5.83 −− 20.25
SD
CV
1 −−
−−
0.099
4.5
2 −−
−−
0.237
4.1
3 −−
−−
0.753
3.7
# Points −− 247 −− 494 −− 405
# Labs 3 3 3
Lipase Coupled enzymatic U/L @ 37° C

Mean −− 22.19 −− 58.32 −− 202.5
SD
CV
1 −−
−−
0.989
4.5
2 −−
−−
2.37
4.1
3 −−
−−
7.53
3.7
# Points −− 247 −− 494 −− 405
# Labs 3 3 3
Method Group • Coupled enzymatic

Mean −− 22.19 −− 58.32 −− 202.5
SD
CV
1 −−
−−
0.989
4.5
2 −−
−−
2.37
4.1
3 −−
−−
7.53
3.7
# Points −− 247 −− 494 −− 405
# Labs 3 3 3
Lipase EIA U/dL @ 37° C

Mean −− 1.75 −− 4.13 −− 12.95
SD
CV
1 −−
−−
0.100
5.7
2 −−
−−
0.155
3.8
3 −−
−−
0.502
3.9
# Points −− 228 −− 228 −− 227
# Labs 1 1 1

Mean 1.85 1.81 5.12 4.87 18.34 17.36
SD
CV
1 0.081
4.4
0.108
6.0
2 0.361
7.0
0.262
5.4
3 1.76
9.6
1.12
6.5
# Points 50 441 49 440 50 442
# Labs 1 1 1 1 1 1

Mean 1.85 1.79 5.12 4.62 18.34 15.86
SD
CV
1 0.081
4.4
0.110
6.1
2 0.361
7.0
0.421
9.1
3 1.76
9.6
2.30
14.5
# Points 50 669 49 668 50 669
# Labs 1 2 1 2 1 2
Lipase EIA U/L @ 37° C

Mean −− 17.46 −− 41.31 −− 129.5
SD
CV
1 −−
−−
1.00
5.7
2 −−
−−
1.55
3.8
3 −−
−−
5.02
3.9
# Points −− 228 −− 228 −− 227
# Labs 1 1 1

Mean 18.54 18.11 51.21 48.74 183.4 173.6
SD
CV
1 0.810
4.4
1.08
6.0
2 3.61
7.0
2.62
5.4
3 17.56
9.6
11.23
6.5
# Points 50 441 49 440 50 442
# Labs 1 1 1 1 1 1

Mean 18.54 17.89 51.21 46.20 183.4 158.6
SD
CV
1 0.810
4.4
1.10
6.1
2 3.61
7.0
4.21
9.1
3 17.56
9.6
22.97
14.5
# Points 50 669 49 668 50 669
# Labs 1 2 1 2 1 2
Lipase Enzymatic with colipase U/dL @ 25° C

Mean −− 206.6 −− −− −− 1469
SD
CV
1 −−
−−
7.22
3.5
−−
−−
2 −−
−−
3 −−
−−
25.28
1.7
# Points −− 452 −− −− −− 477
# Labs 1 1

Method Group • Enzymatic with colipase
Mean −− 206.6 −− −− −− 1469
SD
CV
1 −−
−−
7.22
3.5
2 −−
−−
−−
−−
3 −−
−−
25.28
1.7
# Points −− 452 −− −− −− 477
# Labs 1 1

Mean 1.82 1.88 4.38 4.38 13.78 13.68
SD
CV
1 0.126
6.9
0.133
7.1
2 0.225
5.1
0.238
5.4
3 0.605
4.4
0.598
4.4
# Points 668 25804 480 13264 362 24026
# Labs 26 97 21 63 11 69
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCHITECT Lipase, REF 7D80

Mean 1.72 1.82 4.22 4.30 14.32 13.64
SD
CV
1 0.205
11.9
0.128
7.0
2
0.186
4.4
0.208
4.8
3 0.149
1.0
0.583
4.3
# Points 57 2034 35 1994 20 1814
# Labs 4 9 3 9 2 7
Abbott ARCHITECT/Alinity (c, i, ci models) • DiaSys Diagnostic Systems

Mean 1.85 1.79 3.93 4.05 12.68 12.89
SD
CV
1 0.051
2.8
0.156
8.8
2
0.048
1.2
0.420
10.4
3 0.481
3.8
1.61
12.5
# Points 26 901 13 681 35 643
# Labs 1 2 1 2 2 2
Abbott ARCHITECT/Alinity (c, i, ci models) • Sentinel

Mean −− 1.41 −− 4.34 −− 16.82
SD
CV
1 −−
−−
0.070
5.0
2 −−
−−
0.269
6.2
3 −−
−−
0.934
5.6
# Points −− 1906 −− 1764 −− 1763
# Labs 2 2 2

Mean −− 1.60 −− 5.21 −− 19.71
SD
CV
1 −−
−−
0.083
5.2
2−−
−−
0.232
4.5
3 −−
−−
0.538
2.7
# Points −− 856 −− 280 −− 848
# Labs 5 4 5

Mean −− 1.95 −− 4.52 −− 15.02
SD
CV
1 −−
−−
0.290
14.8
2 −−
−−
0.303
6.7
3 −−
−−
0.724
4.8
# Points −− 132 −− 1583 −− 1267
# Labs 2 7 8

Mean −− −− 3.82 4.24 11.80 13.91
SD
CV
1 −−
−−
−−
−−
2
0.235
6.1
0.397
9.4
3 0.282
2.4
1.23
8.9
# Points −− −− 155 1522 63 1242
# Labs 3 3 1 3

Mean −− 3.67 −− 5.16 −− 14.19
SD
CV
1 −−
−−
0.312
8.5
2 −−
−−
0.326
6.3
3 −−
−−
0.698
4.9
# Points −− 315 −− 296 −− 296
# Labs 1 1 1

Mean −− 2.23 −− 4.92 −− 16.33
SD
CV
1 −−
−−
0.086
3.8
−−
−−
2 0.104
2.1
3 −−
−−
0.475
2.9
# Points −− 1154 −− 96 −− 599
# Labs 4 1 4

Mean −− 5.55 −− 53.06 −− −−
SD
CV
1 −−
−−
0.157
2.8
2 −−
−−
0.701
1.3
3 −−
−−
−−
−−
# Points −− 6 −− 6 −− −−
# Labs 1 1

Mean 1.81 1.87 4.36 4.41 13.71 14.11
SD
CV
1 0.134
7.4
0.264
14.1
2 0.234
5.4
0.895
20.3
3 0.670
4.9
1.42
10.1
# Points 751 33108 528 19964 417 31256
# Labs 31 123 25 90 15 98
Lipase Enzymatic with colipase U/L @ 25° C

Mean −− 2066 −− −− −− 14695
SD
CV
1 −−
−−
72.20
3.5
−−
−−
2 −−
−−
3 −−
−−
252.8
1.7
# Points −− 452 −− −− −− 477
# Labs 1 1

Mean −− 2066 −− −− −− 14695
SD
CV
1 −−
−−
72.20
3.5
2 −−
−−
−−
−−
3 −−
−−
252.8
1.7
# Points −− 452 −− −− −− 477
# Labs 1 1

Mean 18.21 18.79 43.84 43.83 137.8 136.8
SD
CV
1 1.26
6.9
1.33
7.1
2 2.25
5.1
2.38
5.4
3 6.05
4.4
5.98
4.4
# Points 668 25804 480 13264 362 24026
# Labs 26 97 21 63 11 69
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCHITECT Lipase, REF 7D80

Mean 17.25 18.20 42.22 42.96 143.2 136.4
SD
CV
1 2.05
11.9
1.28
7.0
2
1.86
4.4
2.08
4.8
3 1.49
1.0
5.83
4.3
# Points 57 2034 35 1994 20 1814
# Labs 4 9 3 9 2 7
Abbott ARCHITECT/Alinity (c, i, ci models) • DiaSys Diagnostic Systems

Mean 18.50 17.86 39.31 40.48 126.8 128.9
SD
CV
1 0.510
2.8
1.56
8.8
2
0.480
1.2
4.20
10.4
3 4.81
3.8
16.12
12.5
# Points 26 901 13 681 35 643
# Labs 1 2 1 2 2 2
Abbott ARCHITECT/Alinity (c, i, ci models) • Sentinel

Mean −− 14.12 −− 43.39 −− 168.2
SD
CV
1 −−
−−
0.703
5.0
2 −−
−−
2.69
6.2
3 −−
−−
9.34
5.6
# Points −− 1906 −− 1764 −− 1763
# Labs 2 2 2

Mean −− 16.03 −− 52.06 −− 197.1
SD
CV
1 −−
−−
0.834
5.2
2 −−
−−
2.32
4.5
3 −−
−−
5.38
2.7
# Points −− 856 −− 280 −− 848
# Labs 5 4 5

Mean −− 19.54 −− 45.25 −− 150.2
SD
CV
1 −−
−−
2.90
14.8
2 −−
−−
3.03
6.7
3 −−
−−
7.24
4.8
# Points −− 132 −− 1583 −− 1267
# Labs 2 7 8

Mean −− −− 38.18 42.42 118.0 139.1
SD
CV
1 −−
−−
−−
−−
2.35
6.1
2 3.97
9.4
3 2.82
2.4
12.35
8.9
# Points −− −− 155 1522 63 1242
# Labs 3 3 1 3

Mean −− 36.69 −− 51.62 −− 141.9
SD
CV
1 −−
−−
3.12
8.5
2 −−
−−
3.26
6.3
3 −−
−−
6.98
4.9
# Points −− 315 −− 296 −− 296
# Labs 1 1 1

Mean −− 22.31 −− 49.18 −− 163.3
SD
CV
1 −−
−−
0.858
3.8
−−
−−
2 1.04
2.1
3 −−
−−
4.75
2.9
# Points −− 1154 −− 96 −− 599
# Labs 4 1 4

Mean −− 55.47 −− 530.6 −− −−
SD
CV
1 −−
−−
1.57
2.8
2 −−
−−
7.01
1.3
3 −−
−−
−−
−−
# Points −− 6 −− 6 −− −−
# Labs 1 1

Mean 18.15 18.69 43.62 44.10 137.1 141.1
SD
CV
1 1.34
7.4
2.64
14.1
2 2.34
5.4
8.95
20.3
3 6.70
4.9
14.20
10.1
# Points 751 33108 528 19964 417 31256
# Labs 31 123 25 90 15 98
Lipase Enzymatic with colipase−VITROS U/dL @ 37° C

Mean −− −− −− 4.16 −− 12.17
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.309
7.4
3 −−
−−
1.00
8.2
# Points −− −− −− 126 −− 125
# Labs 1 1

Mean 5.35 5.47 50.52 49.91 −− 196.3
SD
CV
1 0.070
1.3
0.310
5.7
2 0.787
1.6
2.94
5.9
3 −−
−−
23.82
12.1
# Points 15 1406 32 823 −− 603
# Labs 1 10 1 9 5

Mean 5.55 5.58 50.21 51.27 219.1 215.4
SD
CV
1 0.372
6.7
0.292
5.2
2 0.516
1.0
1.82
3.6
3 17.33
7.9
17.81
8.3
# Points 87 16569 33 14672 54 4408
# Labs 4 106 2 91 2 38

Mean 5.67 5.61 50.18 49.58 227.3 206.4
SD
CV
1 0.245
4.3
0.254
4.5
2 1.51
3.0
1.66
3.4
3 1.77
0.8
12.32
6.0
# Points 216 10245 157 8085 21 1684
# Labs 9 76 7 62 1 21

Mean 5.65 5.64 48.84 49.17 204.6 204.7
SD
CV
1 0.249
4.4
0.278
4.9
2 1.19
2.4
1.34
2.7
3 10.85
5.3
11.00
5.4
# Points 676 3829 495 3098 178 744
# Labs 29 36 25 30 9 9

Mean 5.69 5.69 47.93 47.93 −− −−
SD
CV
1 0.182
3.2
0.182
3.2
2 0.574
1.2
0.574
1.2
3 −−
−−
−−
−−
# Points 60 60 60 60 −− −−
# Labs 2 2 2 2

Mean −− 6.71 −− −− −− 200.0
SD
CV
1 −−
−−
0.215
3.2
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− 38 −− −− −− 38
# Labs 1 1

Mean −− 6.53 −− −− −− 200.0
SD
CV
1 −−
−−
0.229
3.5
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− 119 −− −− −− 115
# Labs 1 1

Mean −− 5.90 −− −− −− 200.0
SD
CV
1 −−
−−
0.413
7.0
2 −−
−−
−−
−−
3 −−
−−
0.005
0.0
# Points −− 123 −− −− −− 109
# Labs 1 1

Mean 5.60 5.61 48.74 51.81 −− 228.0
SD
CV
1 0.166
3.0
0.174
3.1
2 0.510
1.0
3.64
7.0
3 −−
−−
7.62
3.3
# Points 15 245 15 389 −− 88
# Labs 1 3 1 4 1

Mean −− 5.78 −− 50.43 −− 229.5
SD
CV
1 −−
−−
0.366
6.3
2 −−
−−
2.26
4.5
3 −−
−−
12.64
5.5
# Points −− 3984 −− 5627 −− 1318
# Labs 47 47 17

Mean −− 5.32 −− 48.68 −− −−
SD
CV
1 −−
−−
0.119
2.2
2 −−
−−
0.464
1.0
3 −−
−−
−−
−−
# Points −− 70 −− 32 −− −−
# Labs 2 2

Mean −− 5.63 −− 50.15 −− 214.4
SD
CV
1 −−
−−
0.328
5.8
2 −−
−−
1.90
3.8
3 −−
−−
15.58
7.3
# Points −− 13830 −− 12428 −− 3858
# Labs 84 73 35

Mean −− 6.20 −− 52.40 −− 232.0
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
0.000
0.0
3 −−
−−
0.000
0.0
# Points −− 1 −− 1 −− 1
# Labs 1 1 1

Mean −− 5.36 −− −− −− 226.0
SD
CV
1 −−
−−
0.211
3.9
2 −−
−−
−−
−−
3 −−
−−
7.72
3.4
# Points −− 121 −− −− −− 118
# Labs 2 2
Method Group • Enzymatic with colipase−VITROS

Mean 5.64 5.62 49.16 50.25 209.6 212.5
SD
CV
1 0.259
4.6
0.311
5.5
2 1.38
2.8
3.17
6.3
3 14.48
6.9
26.13
12.3
# Points 1069 50962 792 44976 253 13532
# Labs 46 370 38 320 12 132
Lipase Enzymatic with colipase−VITROS U/L @ 37° C

Mean −− −− −− 41.63 −− 121.7
SD
CV
1 −−
−−
−−
−−
2 −−
−−
3.09
7.4
3 −−
−−
10.03
8.2
# Points −− −− −− 126 −− 125
# Labs 1 1

Mean 53.50 54.68 505.2 499.1 −− 1963
SD
CV
1 0.700
1.3
3.10
5.7
2 7.87
1.6
29.36
5.9
3 −−
−−
238.2
12.1
# Points 15 1406 32 823 −− 603
# Labs 1 10 1 9 5

Mean 55.47 55.76 502.1 512.7 2191 2154
SD
CV
1 3.72
6.7
2.92
5.2
2 5.16
1.0
18.24
3.6
3 173.3
7.9
178.1
8.3
# Points 87 16569 33 14672 54 4408
# Labs 4 106 2 91 2 38

Mean 56.65 56.14 501.8 495.8 2273 2064
SD
CV
1 2.45
4.3
2.54
4.5
2 15.13
3.0
16.63
3.4
3 17.66
0.8
123.2
6.0
# Points 216 10245 157 8085 21 1684
# Labs 9 76 7 62 1 21

Mean 56.54 56.45 488.4 491.7 2046 2047
SD
CV
1 2.49
4.4
2.78
4.9
2 11.85
2.4
13.45
2.7
3 108.5
5.3
110.0
5.4
# Points 676 3829 495 3098 178 744
# Labs 29 36 25 30 9 9

Mean 56.91 56.91 479.3 479.3 −− −−
SD
CV
1 1.82
3.2
1.82
3.2
2 5.74
1.2
5.74
1.2
3 −−
−−
−−
−−
# Points 60 60 60 60 −− −−
# Labs 2 2 2 2

Mean −− 67.12 −− −− −− 2000
SD
CV
1 −−
−−
2.15
3.2
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− 38 −− −− −− 38
# Labs 1 1

Mean −− 65.26 −− −− −− 2000
SD
CV
1 −−
−−
2.29
3.5
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− 119 −− −− −− 115
# Labs 1 1
Lipase Enzymatic with colipase−VITROS U/L @ 37° C

Mean −− 58.96 −− −− −− 2000
SD
CV
1 −−
−−
4.13
7.0
2 −−
−−
−−
−−
3 −−
−−
0.047
0.0
# Points −− 123 −− −− −− 109
# Labs 1 1

Mean 55.96 56.15 487.4 518.1 −− 2280
SD
CV
1 1.66
3.0
1.74
3.1
2 5.10
1.0
36.41
7.0
3 −−
−−
76.17
3.3
# Points 15 245 15 389 −− 88
# Labs 1 3 1 4 1

Mean −− 57.77 −− 504.3 −− 2295
SD
CV
1 −−
−−
3.66
6.3
2 −−
−−
22.65
4.5
3 −−
−−
126.4
5.5
# Points −− 3984 −− 5627 −− 1318
# Labs 47 47 17

Mean −− 53.16 −− 486.8 −− −−
SD
CV
1 −−
−−
1.19
2.2
2 −−
−−
4.64
1.0
3 −−
−−
−−
−−
# Points −− 70 −− 32 −− −−
# Labs 2 2

Mean −− 56.29 −− 501.5 −− 2144
SD
CV
1 −−
−−
3.28
5.8
2 −−
−−
19.02
3.8
3 −−
−−
155.8
7.3
# Points −− 13830 −− 12428 −− 3858
# Labs 84 73 35

Mean −− 62.00 −− 524.0 −− 2320
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
0.000
0.0
3 −−
−−
0.000
0.0
# Points −− 1 −− 1 −− 1
# Labs 1 1 1

Mean −− 53.63 −− −− −− 2260
SD
CV
1 −−
−−
2.11
3.9
2 −−
−−
−−
−−
3 −−
−−
77.23
3.4
# Points −− 121 −− −− −− 118
# Labs 2 2
Method Group • Enzymatic with colipase−VITROS

Mean 56.44 56.20 491.6 502.5 2096 2125
SD
CV
1 2.59
4.6
3.11
5.5
2 13.81
2.8
31.65
6.3
3 144.8
6.9
261.3
12.3
# Points 1069 50962 792 44976 253 13532
# Labs 46 370 38 320 12 132
Lipase Enzymatic, colorimetric U/dL @ 25° C

Mean −− 1.98 −− −− −− 14.56
SD
CV
1 −−
−−
0.247
12.5
2 −−
−−
−−
−−
3 −−
−−
0.987
6.8
# Points −− 359 −− −− −− 371
# Labs 1 1

Mean −− 2.10 −− −− −− 16.89
SD
CV
1 −−
−−
0.093
4.4
2 −−
−−
−−
−−
3 −−
−−
0.656
3.9
# Points −− 1095 −− −− −− 1075
# Labs 2 2

Roche cobas c 303/503 • Roche LIPC, REF 08057982
Mean 2.15 2.10 −− −− 17.95 17.09
SD
CV
1 0.089
4.2
0.097
4.6
2 −−
−−
−−
−−
3 0.680
3.8
0.752
4.4
# Points 85 1803 −− −− 81 1778
# Labs 2 2 2 2

Mean −− 2.23 −− 5.59 −− −−
SD
CV
1 −−
−−
0.110
4.9
2 −−
−−
0.226
4.0
3 −−
−−
−−
−−
# Points −− 45 −− 31 −− −−
# Labs 1 1

Mean 2.15 2.09 −− 5.59 17.95 16.65
SD
CV
1 0.089
4.2
0.143
6.8
2 −−
−−
0.226
4.0
3 0.680
3.8
1.24
7.5
# Points 85 2207 −− 31 81 2149
# Labs 2 4 1 2 3

Mean −− −− −− 4.97 −− 16.64
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.158
3.2
3 −−
−−
0.557
3.3
# Points −− −− −− 502 −− 473
# Labs 1 1

Mean −− −− −− 4.97 −− 16.64
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.158
3.2
3 −−
−−
0.557
3.3
# Points −− −− −− 502 −− 473
# Labs 1 1

Mean 1.93 1.85 4.60 4.53 14.55 14.91
SD
CV
1 0.048
2.5
0.201
10.9
2 0.068
1.5
0.282
6.2
3 0.280
1.9
2.68
18.0
# Points 38 2184 38 1015 38 2247
# Labs 1 9 1 5 1 9

Mean 1.88 1.86 3.82 4.08 11.35 12.76
SD
CV
1 0.061
3.2
0.086
4.6
2
0.098
2.6
0.185
4.5
3 0.475
4.2
0.843
6.6
# Points 15 365 15 407 15 413
# Labs 1 1 1 1 1 1
Abbott ARCHITECT/Alinity (c, i, ci models) • Randox Lipase (Colorimetric)

Mean −− 2.46 −− −− −− 23.08
SD
CV
1 −−
−−
0.031
1.2
−−
−−
2 −−
−−
3 −−
−−
0.363
1.6
# Points −− 47 −− −− −− 48
# Labs 1 1

Mean 1.54 1.51 4.67 4.60 18.56 18.41
SD
CV
1 0.160
10.3
0.123
8.2
2
0.157
3.4
0.418
9.1
3 0.871
4.7
1.53
8.3
# Points 165 6210 125 4125 71 5802
# Labs 6 26 5 21 2 17

Mean 1.67 1.75 4.39 4.45 14.69 14.76
SD
CV
1 0.173
10.4
0.162
9.3
2 0.284
6.5
0.257
5.8
3 0.608
4.1
0.729
4.9
# Points 1453 55151 1163 34211 683 52888
# Labs 46 170 38 111 20 144

Mean −− −− −− 3.79 −− 13.30
SD
CV
1 −−
−−
−−
−−
2−−
−−
0.333
8.8
3 −−
−−
0.920
6.9
# Points −− −− −− 161 −− 161
# Labs 1 1

Mean −− 1.66 −− 4.41 −− 14.50
SD
CV
1 −−
−−
0.132
7.9
2 −−
−−
0.229
5.2
3 −−
−−
0.537
3.7
# Points −− 533 −− 897 −− 880
# Labs 4 5 5

Mean −− 1.99 −− −− −− 14.87
SD
CV
1 −−
−−
0.396
19.8
2 −−
−−
−−
−−
3 −−
−−
2.74
18.4
# Points −− 594 −− −− −− 539
# Labs 2 2

Mean −− −− −− 3.91 −− 12.59
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.300
7.7
3 −−
−−
1.41
11.2
# Points −− −− −− 38 −− 39
# Labs 2 2

Mean −− −− 6.24 6.19 18.65 18.78
SD
CV
1 −−
−−
−−
−−
2 0.089
1.4
0.088
1.4
3 0.265
1.4
0.278
1.5
# Points −− −− 5 15 4 14
# Labs 1 1 1 1

Mean 2.66 2.95 5.70 5.43 −− −−
SD
CV
1 0.158
5.9
0.187
6.3
2 0.356
6.2
0.353
6.5
3 −−
−−
−−
−−
# Points 10 255 10 188 −− −−
# Labs 1 1 1 1

Mean −− 3.66 −− −− −− 14.38
SD
CV
1 −−
−−
0.261
7.1
2 −−
−−
−−
−−
3 −−
−−
0.490
3.4
# Points −− 76 −− −− −− 44
# Labs 1 1

Mean −− 1.77 −− −− −− 22.88
SD
CV
1 −−
−−
0.062
3.5
2 −−
−−
−−
−−
3 −−
−−
0.989
4.3
# Points −− 1030 −− −− −− 619
# Labs 3 3

Mean −− 1.74 −− −− −− −−
SD
CV
1 −−
−−
0.039
2.3
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 62 −− −− −− −−
# Labs 1

Mean −− 1.92 −− −− −− 10.62
SD
CV
1 −−
−−
0.193
10.1
2 −−
−−
−−
−−
3 −−
−−
0.514
4.8
# Points −− 10 −− −− −− 10
# Labs 1 1

Mean −− −− −− 2.91 −− 10.17
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.696
23.9
3 −−
−−
1.85
18.2
# Points −− −− −− 7 −− 6
# Labs 1 1

Mean 1.98 1.99 4.87 4.88 16.71 16.74
SD
CV
1 0.112
5.6
0.111
5.6
2 0.171
3.5
0.190
3.9
3 0.710
4.2
0.753
4.5
# Points 1161 22542 166 10618 1083 23983
# Labs 22 76 5 40 20 78

Mean 1.88 1.98 −− 4.88 16.07 16.92
SD
CV
1 0.111
5.9
0.084
4.2
2 −−
−−
0.185
3.8
3 0.923
5.7
0.695
4.1
# Points 62 4526 −− 1144 60 4905
# Labs 3 13 3 3 14

Mean 1.93 1.97 4.93 4.93 17.07 16.91
SD
CV
1 0.072
3.7
0.075
3.8
0.103
2.1
2 0.120
2.4
3 0.402
2.4
0.463
2.7
# Points 63 1451 64 1473 64 1488
# Labs 2 2 2 2 2 2
Roche cobas 6000/8000/c 311 • Reagent, Alternate Calibration − Shift DOWN

Mean −− 1.91 −− −− −− 16.52
SD
CV
1 −−
−−
0.083
4.3
2
−−
−−
−−
−−
3 −−
−−
0.525
3.2
# Points −− 708 −− −− −− 576
# Labs 2 2

Mean 1.98 1.97 −− 4.99 17.22 16.79
SD
CV
1 0.084
4.2
0.092
4.7
−−
−−
2 0.174
3.5
3 0.512
3.0
0.729
4.3
# Points 352 17946 −− 5131 359 17394
# Labs 7 38 14 7 38
Roche cobas 6000/8000/c 311 • Roche Lipase ACN 789/8789/786/8786 low

Mean 1.98 1.97 4.87 4.83 16.68 16.42
SD
CV
1 0.044
2.2
0.076
3.8
0.060
1.2
2 0.125
2.6
3 0.170
1.0
0.439
2.7
# Points 32 801 32 802 32 809
# Labs 1 1 1 1 1 1

Mean 2.09 2.07 5.04 4.91 16.92 16.43
SD
CV
1 0.060
2.9
0.087
4.2
2 0.099
2.0
0.178
3.6
3 0.399
2.4
0.652
4.0
# Points 88 3623 97 3020 80 3538
# Labs 3 12 3 7 3 12
Roche cobas c 303/503 • Reagent, Alternate Calibration − Shift DOWN

Mean 2.03 2.07 −− −− 16.37 16.00
SD
CV
1 0.068
3.4
0.092
4.5
2
−−
−−
−−
−−
3 0.653
4.0
0.835
5.2
# Points 58 744 −− −− 62 821
# Labs 2 2 2 2

Mean 2.07 2.06 5.02 4.98 17.08 16.63
SD
CV
1 0.067
3.3
0.109
5.3
2 0.122
2.4
0.238
4.8
3 0.591
3.5
0.853
5.1
# Points 117 6678 163 2186 86 6489
# Labs 4 24 4 11 3 23

Mean 1.38 1.53 4.68 4.85 17.72 17.69
SD
CV
1 0.113
8.2
0.206
13.5
2 0.212
4.5
0.223
4.6
3 0.553
3.1
0.786
4.4
# Points 62 213 62 219 62 247
# Labs 2 3 2 3 2 4

Mean 2.00 2.04 4.60 4.57 14.40 14.86
SD
CV
1 0.100
5.0
0.113
5.5
2 0.100
2.2
0.240
5.2
3 0.200
1.4
1.02
6.9
# Points 32 1108 32 757 32 1099
# Labs 1 3 1 1 1 3

Mean −− 1.96 −− −− −− 15.82
SD
CV
1 −−
−−
0.054
2.7
2 −−
−−
−−
−−
3 −−
−−
0.766
4.8
# Points −− 296 −− −− −− 288
# Labs 1 1
Roche cobas Integra / c 111 • Reagent, Alternate Calibration − Shift UP

Mean 2.00 1.98 −− −− 16.55 16.44
SD
CV
1 0.036
1.8
0.063
3.2
2 −−
−−
−−
−−
3 0.293
1.8
0.680
4.1
# Points 35 957 −− −− 35 958
# Labs 1 2 1 2

Mean 1.61 2.03 5.21 4.94 19.50 16.30
SD
CV
1 0.065
4.0
0.452
22.3
2 0.223
4.3
0.664
13.4
3 0.590
3.0
1.75
10.7
# Points 31 822 31 819 31 819
# Labs 1 3 1 3 1 3
Mean −− 2.01 −− 4.75 −− 16.29
SD
CV
1 −−
−−
0.218
10.9
2 −−
−−
0.419
8.8
3 −−
−−
1.27
7.8
# Points −− 235 −− 345 −− 338
# Labs 1 1 1

Mean −− 1.86 −− −− −− 21.33
SD
CV
1 −−
−−
0.072
3.9
2 −−
−−
−−
−−
3 −−
−−
0.920
4.3
# Points −− 276 −− −− −− 277
# Labs 1 1

Mean 2.47 2.43 5.86 5.94 19.93 20.16
SD
CV
1 0.129
5.2
0.148
6.1
2 0.287
4.9
0.298
5.0
3 1.11
5.6
1.000
5.0
# Points 124 6800 90 4743 88 5790
# Labs 4 19 3 15 3 16

Mean −− 2.90 −− 5.68 −− 15.48
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
0.577
10.2
3 −−
−−
0.365
2.4
# Points −− 2 −− 10 −− 10
# Labs 2 2 2

Mean 2.36 2.32 5.88 5.78 19.48 19.53
SD
CV
1 0.131
5.6
0.179
7.7
2 0.183
3.1
0.272
4.7
3 0.436
2.2
0.659
3.4
# Points 505 22168 383 9131 171 16761
# Labs 14 68 11 41 8 53

Mean −− 2.19 −− −− −− 16.07
SD
CV
1 −−
−−
0.128
5.9
−−
−−
2 −−
−−
3 −−
−−
0.615
3.8
# Points −− 105 −− −− −− 105
# Labs 1 1

Mean −− −− 4.65 4.72 −− −−
SD
CV
1 −−
−−
−−
−−
2 0.575
12.4
0.530
11.2
3 −−
−−
−−
−−
# Points −− −− 9 14 −− −−
# Labs 1 1

Mean 1.91 1.95 4.83 4.84 16.58 16.48
SD
CV
1 0.292
15.3
0.284
14.6
2 0.620
12.8
0.573
11.8
3 1.61
9.7
2.01
12.2
# Points 4278 153K 2421 78805 2932 144K
# Labs 117 479 79 288 77 431
Lipase Enzymatic, colorimetric U/L @ 25° C

Mean −− 19.79 −− −− −− 145.6
SD
CV
1 −−
−−
2.47
12.5
2 −−
−−
−−
−−
3 −−
−−
9.87
6.8
# Points −− 359 −− −− −− 371
# Labs 1 1

Mean −− 21.04 −− −− −− 168.9
SD
CV
1 −−
−−
0.930
4.4
2 −−
−−
−−
−−
3 −−
−−
6.56
3.9
# Points −− 1095 −− −− −− 1075
# Labs 2 2

Mean 21.52 21.04 −− −− 179.5 170.9
SD
CV
1 0.894
4.2
0.971
4.6
2 −−
−−
−−
−−
3 6.80
3.8
7.52
4.4
# Points 85 1803 −− −− 81 1778
# Labs 2 2 2 2

Mean −− 22.32 −− 55.94 −− −−
SD
CV
1 −−
−−
1.10
4.9
2 −−
−−
2.26
4.0
3 −−
−−
−−
−−
# Points −− 45 −− 31 −− −−
# Labs 1 1

Mean 21.52 20.87 −− 55.94 179.5 166.5
SD
CV
1 0.894
4.2
1.43
6.8
2 −−
−−
2.26
4.0
3 6.80
3.8
12.45
7.5
# Points 85 2207 −− 31 81 2149
# Labs 2 4 1 2 3

Mean −− −− −− 49.69 −− 166.4
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.58
3.2
3 −−
−−
5.57
3.3
# Points −− −− −− 502 −− 473
# Labs 1 1

Mean −− −− −− 49.69 −− 166.4
SD
CV
1 −−
−−
−−
−−
2 −−
−−
1.58
3.2
3 −−
−−
5.57
3.3
# Points −− −− −− 502 −− 473
# Labs 1 1

Mean 19.26 18.53 45.99 45.30 145.5 149.1
SD
CV
1 0.480
2.5
2.01
10.9
2 0.680
1.5
2.82
6.2
3 2.80
1.9
26.79
18.0
# Points 38 2184 38 1015 38 2247
# Labs 1 9 1 5 1 9

Mean 18.82 18.63 38.20 40.79 113.5 127.6
SD
CV
1 0.610
3.2
0.855
4.6
2
0.980
2.6
1.85
4.5
3 4.75
4.2
8.43
6.6
# Points 15 365 15 407 15 413
# Labs 1 1 1 1 1 1
Abbott ARCHITECT/Alinity (c, i, ci models) • Randox Lipase (Colorimetric)

Mean −− 24.60 −− −− −− 230.8
SD
CV
1 −−
−−
0.305
1.2
2 −−
−−
−−
−−
3 −−
−−
3.63
1.6
# Points −− 47 −− −− −− 48
# Labs 1 1

Mean 15.42 15.11 46.71 45.96 185.6 184.1
SD
CV
1 1.60
10.3
1.23
8.2
2 1.57
3.4
4.18
9.1
3 8.71
4.7
15.28
8.3
# Points 165 6210 125 4125 71 5802
# Labs 6 26 5 21 2 17

Mean 16.69 17.48 43.92 44.46 146.9 147.6
SD
CV
1 1.73
10.4
1.62
9.3
2 2.84
6.5
2.57
5.8
3 6.08
4.1
7.29
4.9
# Points 1453 55151 1163 34211 683 52888
# Labs 46 170 38 111 20 144

Mean −− −− −− 37.87 −− 133.0
SD
CV
1 −−
−−
−−
−−
2−−
−−
3.33
8.8
3 −−
−−
9.20
6.9
# Points −− −− −− 161 −− 161
# Labs 1 1

Mean −− 16.64 −− 44.05 −− 145.0
SD
CV
1 −−
−−
1.32
7.9
2 −−
−−
2.29
5.2
3 −−
−−
5.37
3.7
# Points −− 533 −− 897 −− 880
# Labs 4 5 5

Mean −− 19.94 −− −− −− 148.7
SD
CV
1 −−
−−
3.96
19.8
2 −−
−−
−−
−−
3 −−
−−
27.38
18.4
# Points −− 594 −− −− −− 539
# Labs 2 2

Mean −− −− −− 39.13 −− 125.9
SD
CV
1 −−
−−
−−
−−
2 −−
−−
3.00
7.7
3 −−
−−
14.10
11.2
# Points −− −− −− 38 −− 39
# Labs 2 2

Mean −− −− 62.40 61.93 186.5 187.8
SD
CV
1 −−
−−
−−
−−
2 0.890
1.4
0.880
1.4
3 2.65
1.4
2.78
1.5
# Points −− −− 5 15 4 14
# Labs 1 1 1 1

Mean 26.60 29.50 57.00 54.27 −− −−
SD
CV
1 1.58
5.9
1.87
6.3
2 3.56
6.2
3.53
6.5
3 −−
−−
−−
−−
# Points 10 255 10 188 −− −−
# Labs 1 1 1 1

Mean −− 36.55 −− −− −− 143.8
SD
CV
1 −−
−−
2.61
7.1
2 −−
−−
−−
−−
3 −−
−−
4.90
3.4
# Points −− 76 −− −− −− 44
# Labs 1 1

Mean −− 17.73 −− −− −− 228.8
SD
CV
1 −−
−−
0.621
3.5
2 −−
−−
−−
−−
3 −−
−−
9.89
4.3
# Points −− 1030 −− −− −− 619
# Labs 3 3

Mean −− 17.44 −− −− −− −−
SD
CV
1 −−
−−
0.394
2.3
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 62 −− −− −− −−
# Labs 1

Mean −− 19.20 −− −− −− 106.2
SD
CV
1 −−
−−
1.93
10.1
2 −−
−−
−−
−−
3 −−
−−
5.14
4.8
# Points −− 10 −− −− −− 10
# Labs 1 1

Mean −− −− −− 29.14 −− 101.7
SD
CV
1 −−
−−
−−
−−
2 −−
−−
6.96
23.9
3 −−
−−
18.50
18.2
# Points −− −− −− 7 −− 6
# Labs 1 1

Mean 19.78 19.89 48.68 48.77 167.1 167.4
SD
CV
1 1.12
5.6
1.11
5.6
2 1.71
3.5
1.90
3.9
3 7.10
4.2
7.53
4.5
# Points 1161 22542 166 10618 1083 23983
# Labs 22 76 5 40 20 78

Mean 18.82 19.81 −− 48.81 160.7 169.2
SD
CV
1 1.11
5.9
0.840
4.2
2 −−
−−
1.85
3.8
3 9.23
5.7
6.95
4.1
# Points 62 4526 −− 1144 60 4905
# Labs 3 13 3 3 14

Mean 19.35 19.72 49.30 49.26 170.7 169.1
SD
CV
1 0.722
3.7
0.748
3.8
2
1.03
2.1
1.20
2.4
3 4.02
2.4
4.63
2.7
# Points 63 1451 64 1473 64 1488
# Labs 2 2 2 2 2 2
Roche cobas 6000/8000/c 311 • Reagent, Alternate Calibration − Shift DOWN

Mean −− 19.13 −− −− −− 165.2
SD
CV
1 −−
−−
0.827
4.3
2 −−
−−
−−
−−
3 −−
−−
5.25
3.2
# Points −− 708 −− −− −− 576
# Labs 2 2

Mean 19.81 19.70 −− 49.86 172.2 167.9
SD
CV
1 0.835
4.2
0.923
4.7
2
−−
−−
1.74
3.5
3 5.12
3.0
7.29
4.3
# Points 352 17946 −− 5131 359 17394
# Labs 7 38 14 7 38
Roche cobas 6000/8000/c 311 • Roche Lipase ACN 789/8789/786/8786 low

Mean 19.75 19.75 48.66 48.30 166.8 164.2
SD
CV
1 0.440
2.2
0.759
3.8
2
0.602
1.2
1.25
2.6
3 1.70
1.0
4.39
2.7
# Points 32 801 32 802 32 809
# Labs 1 1 1 1 1 1

Mean 20.90 20.68 50.35 49.11 169.2 164.3
SD
CV
1 0.598
2.9
0.868
4.2
2 0.985
2.0
1.78
3.6
3 3.99
2.4
6.52
4.0
# Points 88 3623 97 3020 80 3538
# Labs 3 12 3 7 3 12
Roche cobas c 303/503 • Reagent, Alternate Calibration − Shift DOWN

Mean 20.29 20.67 −− −− 163.7 160.0
SD
CV
1 0.683
3.4
0.925
4.5
2 −−
−−
−−
−−
3 6.53
4.0
8.35
5.2
# Points 58 744 −− −− 62 821
# Labs 2 2 2 2

Mean 20.74 20.59 50.19 49.81 170.8 166.3
SD
CV
1 0.674
3.3
1.09
5.3
2 1.22
2.4
2.38
4.8
3 5.91
3.5
8.53
5.1
# Points 117 6678 163 2186 86 6489
# Labs 4 24 4 11 3 23

Mean 13.79 15.30 46.82 48.53 177.2 176.9
SD
CV
1 1.13
8.2
2.06
13.5
2 2.12
4.5
2.23
4.6
3 5.53
3.1
7.86
4.4
# Points 62 213 62 219 62 247
# Labs 2 3 2 3 2 4

Mean 20.00 20.39 46.00 45.71 144.0 148.6
SD
CV
1 1.00
5.0
1.13
5.5
2 1.00
2.2
2.40
5.2
3 2.00
1.4
10.25
6.9
# Points 32 1108 32 757 32 1099
# Labs 1 3 1 1 1 3

Mean −− 19.62 −− −− −− 158.2
SD
CV
1 −−
−−
0.538
2.7
2 −−
−−
−−
−−
3 −−
−−
7.66
4.8
# Points −− 296 −− −− −− 288
# Labs 1 1

Roche cobas Integra / c 111 • Reagent, Alternate Calibration − Shift UP
Mean 20.04 19.84 −− −− 165.5 164.4
SD
CV
1 0.360
1.8
0.634
3.2
2
−−
−−
−−
−−
3 2.93
1.8
6.80
4.1
# Points 35 957 −− −− 35 958
# Labs 1 2 1 2

Mean 16.10 20.32 52.10 49.41 195.0 163.0
SD
CV
1 0.650
4.0
4.52
22.3
2 2.23
4.3
6.64
13.4
3 5.90
3.0
17.51
10.7
# Points 31 822 31 819 31 819
# Labs 1 3 1 3 1 3
Mean −− 20.12 −− 47.46 −− 162.9
SD
CV
1 −−
−−
2.18
10.9
2 −−
−−
4.19
8.8
3 −−
−−
12.69
7.8
# Points −− 235 −− 345 −− 338
# Labs 1 1 1

Mean −− 18.62 −− −− −− 213.3
SD
CV
1 −−
−−
0.724
3.9
2 −−
−−
−−
−−
3 −−
−−
9.20
4.3
# Points −− 276 −− −− −− 277
# Labs 1 1

Mean 24.66 24.34 58.60 59.35 199.3 201.6
SD
CV
1 1.29
5.2
1.48
6.1
2 2.87
4.9
2.98
5.0
3 11.09
5.6
10.00
5.0
# Points 124 6800 90 4743 88 5790
# Labs 4 19 3 15 3 16

Mean −− 29.00 −− 56.80 −− 154.8
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
5.77
10.2
3 −−
−−
3.65
2.4
# Points −− 2 −− 10 −− 10
# Labs 2 2 2

Mean 23.57 23.20 58.77 57.85 194.8 195.3
SD
CV
1 1.31
5.6
1.79
7.7
2 1.83
3.1
2.72
4.7
3 4.36
2.2
6.59
3.4
# Points 505 22168 383 9131 171 16761
# Labs 14 68 11 41 8 53

Mean −− 21.91 −− −− −− 160.7
SD
CV
1 −−
−−
1.28
5.9
−−
−−
2 −−
−−
3 −−
−−
6.15
3.8
# Points −− 105 −− −− −− 105
# Labs 1 1

Mean −− −− 46.49 47.23 −− −−
SD
CV
1 −−
−−
−−
−−
2 5.75
12.4
5.30
11.2
3 −−
−−
−−
−−
# Points −− −− 9 14 −− −−
# Labs 1 1

Mean 19.11 19.51 48.33 48.38 165.8 164.8
SD
CV
1 2.92
15.3
2.84
14.6
2 6.20
12.8
5.73
11.8
3 16.13
9.7
20.11
12.2
# Points 4278 153K 2421 78805 2932 144K
# Labs 117 479 79 288 77 431
Lipase Immunoturbidimetric U/dL @ 37° C

Mean −− 2.37 −− −− −− 13.02
SD
CV
1 −−
−−
0.243
10.2
2 −−
−−
−−
−−
3 −−
−−
1.47
11.3
# Points −− 15 −− −− −− 307
# Labs 1 1

Mean −− 2.37 −− −− −− 13.02
SD
CV
1 −−
−−
0.243
10.2
2 −−
−−
−−
−−
3 −−
−−
1.47
11.3
# Points −− 15 −− −− −− 307
# Labs 1 1
Lipase Immunoturbidimetric U/L @ 37° C

Mean −− 23.73 −− −− −− 130.2
SD
CV
1 −−
−−
2.43
10.2
2 −−
−−
−−
−−
3 −−
−−
14.74
11.3
# Points −− 15 −− −− −− 307
# Labs 1 1

Mean −− 23.73 −− −− −− 130.2
SD
CV
1 −−
−−
2.43
10.2
2 −−
−−
−−
−−
3 −−
−−
14.74
11.3
# Points −− 15 −− −− −− 307
# Labs 1 1
Lipase Nephelometric U/dL @ 37° C

Siemens Dimension Series • Siemens Dimension Vista LIP REF K3056A
Mean 2.26 2.26 −− −− 15.28 15.54
SD
CV
1 0.000
0.0
0.001
0.1
2
−−
−−
−−
−−
3 0.000
0.0
0.365
2.3
# Points 1 2 −− −− 1 2
# Labs 1 1 1 1
Method Group • Nephelometric

Mean 2.26 2.26 −− −− 15.28 15.54
SD
CV
1 0.000
0.0
0.001
0.1
2 −−
−−
−−
−−
3 0.000
0.0
0.365
2.3
# Points 1 2 −− −− 1 2
# Labs 1 1 1 1
Lipase Nephelometric U/L @ 37° C

Siemens Dimension Series • Siemens Dimension Vista LIP REF K3056A
Mean 22.62 22.63 −− −− 152.8 155.4
SD
CV
1 0.000
0.0
0.013
0.1
2
−−
−−
−−
−−
3 0.000
0.0
3.65
2.3
# Points 1 2 −− −− 1 2
# Labs 1 1 1 1
Method Group • Nephelometric

Mean 22.62 22.63 −− −− 152.8 155.4
SD
CV
1 0.000
0.0
0.013
0.1
2 −−
−−
−−
−−
3 0.000
0.0
3.65
2.3
# Points 1 2 −− −− 1 2
# Labs 1 1 1 1
Lipase Photometric, kinetic U/dL @ 37° C

Mean −− 2.35 −− −− −− 14.16
SD
CV
1 −−
−−
0.156
6.7
2 −−
−−
−−
−−
3 −−
−−
0.595
4.2
# Points −− 237 −− −− −− 236
# Labs 2 2
Lipase Photometric, kinetic U/dL @ 37° C

Mean 3.18 3.55 4.75 5.23 −− −−
SD
CV
1 0.045
1.4
0.240
6.8
2 0.058
1.2
0.271
5.2
3 −−
−−
−−
−−
# Points 5 76 4 74 −− −−
# Labs 1 1 1 1
Method Group • Photometric, kinetic

Mean 3.18 2.64 4.75 5.23 −− 14.16
SD
CV
1 0.045
1.4
0.548
20.8
2 0.058
1.2
0.271
5.2
3 −−
−−
0.595
4.2
# Points 5 313 4 74 −− 236
# Labs 1 3 1 1 2
Lipase Photometric, kinetic U/L @ 37° C

Mean −− 23.45 −− −− −− 141.6
SD
CV
1 −−
−−
1.56
6.7
2 −−
−−
−−
−−
3 −−
−−
5.95
4.2
# Points −− 237 −− −− −− 236
# Labs 2 2

Mean 31.80 35.51 47.50 52.27 −− −−
SD
CV
1 0.447
1.4
2.40
6.8
2 0.577
1.2
2.71
5.2
3 −−
−−
−−
−−
# Points 5 76 4 74 −− −−
# Labs 1 1 1 1
Method Group • Photometric, kinetic

Mean 31.80 26.38 47.50 52.27 −− 141.6
SD
CV
1 0.447
1.4
5.48
20.8
2 0.577
1.2
2.71
5.2
3 −−
−−
5.95
4.2
# Points 5 313 4 74 −− 236
# Labs 1 3 1 1 2
Lipase UV U/dL @ 37° C

Mean −− −− −− 4.67 −− 14.55
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.081
1.7
3 −−
−−
0.295
2.0
# Points −− −− −− 166 −− 164
# Labs 1 1
Method Group • UV
Mean −− −− −− 4.67 −− 14.55
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.081
1.7
3 −−
−−
0.295
2.0
# Points −− −− −− 166 −− 164
# Labs 1 1
Lipase UV U/L @ 37° C

Mean −− −− −− 46.69 −− 145.5
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.807
1.7
3 −−
−−
2.95
2.0
# Points −− −− −− 166 −− 164
# Labs 1 1
Method Group • UV
Mean −− −− −− 46.69 −− 145.5
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.807
1.7
3 −−
−−
2.95
2.0
# Points −− −− −− 166 −− 164
# Labs 1 1
Lithium AAS (Atomic Absorption Spectroscopy) mEq/L

Mean −− 0.520 −− 0.960 −− 1.95
SD
CV
1 −−
−−
0.024
4.5
2 −−
−−
0.050
5.2
3 −−
−−
0.055
2.8
# Points −− 1689 −− 593 −− 1745
# Labs 4 1 4

Mean −− 0.520 −− 0.960 −− 1.95
SD
CV
1 −−
−−
0.024
4.5
2 −−
−−
0.050
5.2
3 −−
−−
0.055
2.8
# Points −− 1689 −− 593 −− 1745
# Labs 4 1 4
Lithium Colorimetric mEq/L

Mean 0.511 0.527 0.944 0.955 1.94 1.96
SD
CV
1 0.040
7.9
0.035
6.7
2 0.046
4.9
0.043
4.5
3 0.043
2.2
0.068
3.5
# Points 170 8192 58 3702 122 7869
# Labs 7 41 4 21 4 35
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c Lithium, REF 08P53

Mean −− 0.490 −− −− −− −−
SD
CV
1 −−
−−
0.060
12.2
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 3 −− −− −− −−
# Labs 1

Mean 0.518 0.522 −− 0.966 2.00 1.97
SD
CV
1 0.038
7.4
0.024
4.7
2 −−
−−
0.034
3.6
3 0.011
0.5
0.045
2.3
# Points 90 9474 −− 5252 88 9323
# Labs 3 31 17 3 31

Mean −− 0.535 −− 0.953 −− 2.02
SD
CV
1 −−
−−
0.033
6.1
2 −−
−−
0.062
6.5
3 −−
−−
0.054
2.7
# Points −− 967 −− 150 −− 946
# Labs 5 2 5

Mean 0.567 0.573 1.00 0.997 2.00 2.04
SD
CV
1 0.029
5.0
0.047
8.2
2 0.037
3.7
0.044
4.4
3 0.050
2.5
0.087
4.3
# Points 119 4957 31 2011 119 4975
# Labs 3 15 1 9 3 15

Mean 0.566 0.560 1.00 0.985 2.02 2.00
SD
CV
1 0.018
3.3
0.014
2.6
2 0.030
3.0
0.017
1.7
3 0.050
2.5
0.037
1.8
# Points 25 490 25 348 26 460
# Labs 1 3 1 1 1 3
Roche cobas c 303/503 • Roche LI, REF 08057974

Mean −− 0.820 −− −− −− 2.91
SD
CV
1 −−
−−
0.043
5.2
2 −−
−−
−−
−−
3 −−
−−
0.101
3.5
# Points −− 596 −− −− −− 602
# Labs 5 5

Mean 0.587 0.564 0.960 0.986 1.96 1.99
SD
CV
1 0.036
6.1
0.042
7.5
2 0.040
4.2
0.048
4.8
3 0.094
4.8
0.069
3.5
# Points 53 4891 22 3470 53 4216
# Labs 2 13 1 9 2 11

Siemens ADVIA Chemistry Systems • Siemens Atellica CH Lithium_2, REF 11532401
Mean −− 0.529 −− 0.958 −− −−
SD
CV
1 −−
−−
0.030
5.7
−−
−−
20.059
6.2
3 −−
−−
−−
−−
# Points −− 8 −− 8 −− −−
# Labs 1 1

Mean 0.535 0.573 0.945 0.973 −− 1.95
SD
CV
1 0.007
1.3
0.042
7.4
2 0.007
0.7
0.036
3.7
3 −−
−−
0.057
2.9
# Points 2 4071 2 1050 −− 4016
# Labs 1 25 1 7 23
Siemens Atellica CH Analyzer • 2nd Generation

Mean −− 0.569 −− −− −− 1.95
SD
CV
1 −−
−−
0.035
6.1
2 −−
−−
−−
−−
3 −−
−−
0.058
3.0
# Points −− 264 −− −− −− 265
# Labs 2 2
Siemens Atellica CH Analyzer • Siemens Atellica CH Lithium_2, REF 11532401

Mean 0.660 0.609 −− −− 2.07 2.00
SD
CV
1 0.063
9.5
0.054
8.9
−−
−−
2 −−
−−
3 0.045
2.2
0.059
2.9
# Points 66 828 −− −− 66 833
# Labs 2 2 2 2

Mean 0.462 0.457 1.02 1.03 2.23 2.18
SD
CV
1 0.035
7.5
0.045
9.7
2 0.018
1.8
0.033
3.2
3 0.072
3.2
0.089
4.1
# Points 59 3504 27 519 59 3365
# Labs 2 14 1 3 2 13

Mean 0.540 0.535 0.973 0.982 2.04 2.03
SD
CV
1 0.037
6.9
0.037
6.8
2 0.030
3.1
0.033
3.4
3 0.049
2.4
0.046
2.3
# Points 458 61077 204 17372 372 56661
# Labs 16 146 6 36 12 139

Mean −− 0.680 −− −− −− 1.80
SD
CV
1 −−
−−
0.020
2.9
2 −−
−−
−−
−−
3 −−
−−
0.041
2.3
# Points −− 31 −− −− −− 32
# Labs 1 1

Mean −− 0.609 −− −− −− 1.52
SD
CV
1 −−
−−
0.027
4.5
2 −−
−−
−−
−−
3 −−
−−
0.054
3.6
# Points −− 133 −− −− −− 129
# Labs 1 1

Mean −− 0.661 −− −− −− 1.75
SD
CV
1 −−
−−
0.035
5.3
2 −−
−−
−−
−−
3 −−
−−
0.108
6.2
# Points −− 327 −− −− −− 366
# Labs 2 2

Mean 0.666 0.657 0.967 1.05 1.60 1.62
SD
CV
1 0.062
9.2
0.045
6.9
2 0.028
2.9
0.055
5.2
3 0.090
5.6
0.088
5.4
# Points 143 9682 31 4008 144 9360
# Labs 6 32 1 12 6 29

Mean −− 0.630 −− −− −− 1.73
SD
CV
1 −−
−−
0.031
4.9
2 −−
−−
−−
−−
3 −−
−−
0.058
3.3
# Points −− 97 −− −− −− 94
# Labs 1 1

Mean −− 0.616 −− −− −− 1.57
SD
CV
1 −−
−−
0.021
3.3
2 −−
−−
−−
−−
3 −−
−−
0.032
2.0
# Points −− 66 −− −− −− 65
# Labs 2 2

Mean 0.557 0.549 0.975 0.986 1.97 1.99
SD
CV
1 0.069
12.5
0.059
10.7
2 0.038
3.9
0.047
4.7
3 0.169
8.6
0.154
7.8
# Points 1185 110K 400 38024 1049 104K
# Labs 43 343 16 119 35 320
Lithium ISE direct mEq/L

Mean −− 0.508 −− −− −− 2.06
SD
CV
1 −−
−−
0.021
4.1
2 −−
−−
−−
−−
3 −−
−−
0.048
2.3
# Points −− 653 −− −− −− 652
# Labs 1 1

Mean −− 0.559 −− 1.000 −− 2.04
SD
CV
1 −−
−−
0.026
4.7
2 −−
−−
0.031
3.1
3 −−
−−
0.044
2.2
# Points −− 849 −− 853 −− 852
# Labs 1 1 1

Mean −− −− 0.920 0.926 −− −−
SD
CV
1 −−
−−
−−
−−
2 0.024
2.6
0.027
2.9
3 −−
−−
−−
−−
# Points −− −− 24 34 −− −−
# Labs 1 1

Mean −− 0.537 0.920 0.997 −− 2.05
SD
CV
1 −−
−−
0.035
6.5
2 0.024
2.6
0.034
3.4
3 −−
−−
0.046
2.3
# Points −− 1502 24 887 −− 1504
# Labs 2 1 2 2
Lithium ISE indirect mEq/L

Mean −− 0.540 −− 1.01 −− 2.15
SD
CV
1 −−
−−
0.028
5.2
2 −−
−−
0.042
4.2
3 −−
−−
0.028
1.3
# Points −− 2 −− 2 −− 2
# Labs 2 2 2

Mean −− 0.540 −− 1.01 −− 2.15
SD
CV
1 −−
−−
0.028
5.2
2 −−
−−
0.042
4.2
3 −−
−−
0.028
1.3
# Points −− 2 −− 2 −− 2
# Labs 2 2 2
Magnesium AAS (Atomic Absorption Spectroscopy) mEq/L

Mean −− −− −− 2.09 −− 3.37
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.057
2.7
3 −−
−−
0.076
2.3
# Points −− −− −− 593 −− 594
# Labs 3 3

Mean −− −− −− 2.09 −− 3.37
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.057
2.7
3 −−
−−
0.076
2.3
# Points −− −− −− 593 −− 594
# Labs 3 3
Magnesium AAS (Atomic Absorption Spectroscopy) mg/dL

Mean −− −− −− 2.54 −− 4.10
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.070
2.7
3 −−
−−
0.093
2.3
# Points −− −− −− 593 −− 594
# Labs 3 3

Mean −− −− −− 2.54 −− 4.10
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.070
2.7
3 −−
−−
0.093
2.3
# Points −− −− −− 593 −− 594
# Labs 3 3
Magnesium Arsenazo I mEq/L

Mean 0.795 0.802 2.02 2.05 3.31 3.32
SD
CV
1 0.035
4.4
0.046
5.7
2 0.063
3.1
0.060
2.9
3 0.073
2.2
0.095
2.9
# Points 179 9340 112 3552 184 8537
# Labs 7 28 7 15 8 27
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH MAG REF 03P68

Mean 0.805 0.798 2.07 2.06 −− −−
SD
CV
1 0.019
2.3
0.028
3.5
2
0.039
1.9
0.055
2.7
3 −−
−−
−−
−−
# Points 31 107 31 107 −− −−
# Labs 1 1 1 1

Mean −− 1.19 −− 2.27 −− 3.42
SD
CV
1 −−
−−
0.147
12.4
2 −−
−−
0.141
6.2
3 −−
−−
0.106
3.1
# Points −− 146 −− 166 −− 164
# Labs 1 1 1
Method Group • Arsenazo I

Mean 0.796 0.808 2.03 2.06 3.31 3.32
SD
CV
1 0.035
4.4
0.068
8.4
2 0.070
3.4
0.079
3.8
3 0.073
2.2
0.096
2.9
# Points 232 9615 165 3847 184 8701
# Labs 9 31 9 18 8 28
Magnesium Arsenazo I mg/dL

Mean 0.966 0.975 2.46 2.49 4.02 4.03
SD
CV
1 0.043
4.4
0.056
5.7
2 0.076
3.1
0.073
2.9
3 0.089
2.2
0.116
2.9
# Points 179 9340 112 3552 184 8537
# Labs 7 28 7 15 8 27
Magnesium Arsenazo I mg/dL

Mean 0.979 0.970 2.52 2.51 −− −−
SD
CV
1 0.023
2.3
0.034
3.5
2
0.048
1.9
0.067
2.7
3 −−
−−
−−
−−
# Points 31 107 31 107 −− −−
# Labs 1 1 1 1

Mean −− 1.44 −− 2.76 −− 4.15
SD
CV
1 −−
−−
0.179
12.4
2 −−
−−
0.172
6.2
3 −−
−−
0.129
3.1
# Points −− 146 −− 166 −− 164
# Labs 1 1 1
Method Group • Arsenazo I

Mean 0.967 0.982 2.46 2.51 4.02 4.03
SD
CV
1 0.043
4.4
0.083
8.4
2 0.085
3.4
0.096
3.8
3 0.089
2.2
0.117
2.9
# Points 232 9615 165 3847 184 8701
# Labs 9 31 9 18 8 28
Magnesium Calmagite mEq/L

Mean −− 0.826 −− 2.08 −− 3.34
SD
CV
1 −−
−−
0.043
5.2
2 −−
−−
0.096
4.6
3 −−
−−
0.111
3.3
# Points −− 1452 −− 1447 −− 1527
# Labs 4 2 4

Mean 0.815 0.835 −− 2.09 3.26 3.35
SD
CV
1 0.028
3.4
0.038
4.6
2 −−
−−
0.070
3.4
3 0.141
4.3
0.082
2.4
# Points 61 9892 −− 3052 64 9117
# Labs 2 32 12 2 29
Method Group • Calmagite

Mean 0.815 0.834 −− 2.09 3.26 3.35
SD
CV
1 0.028
3.4
0.039
4.7
2 −−
−−
0.080
3.8
3 0.141
4.3
0.087
2.6
# Points 61 11345 −− 4499 64 10644
# Labs 2 36 14 2 33
Magnesium Calmagite mg/dL

Mean −− 1.00 −− 2.53 −− 4.06
SD
CV
1 −−
−−
0.052
5.2
2 −−
−−
0.117
4.6
3 −−
−−
0.135
3.3
# Points −− 1452 −− 1447 −− 1527
# Labs 4 2 4

Mean 0.991 1.02 −− 2.54 3.96 4.08
SD
CV
1 0.034
3.4
0.046
4.6
2 −−
−−
0.085
3.4
3 0.171
4.3
0.100
2.4
# Points 61 9892 −− 3052 64 9117
# Labs 2 32 12 2 29
Method Group • Calmagite

Mean 0.991 1.01 −− 2.54 3.96 4.07
SD
CV
1 0.034
3.4
0.047
4.7
2 −−
−−
0.097
3.8
3 0.171
4.3
0.106
2.6
# Points 61 11345 −− 4499 64 10644
# Labs 2 36 14 2 33
Magnesium Chlorophosphonazo III mEq/L

Mean 0.790 0.827 −− 2.10 3.35 3.35
SD
CV
1 0.049
6.3
0.035
4.2
2 −−
−−
0.041
2.0
3 0.082
2.5
0.072
2.1
# Points 241 1696 −− 1614 239 1835
# Labs 1 7 6 1 8
Roche cobas 6000/c 311 • Alternate Calibration

Mean −− 0.905 −− −− −− 3.37
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− 1 −− −− −− 1
# Labs 1 1
Roche cobas 8000

Mean −− 0.850 −− 2.11 −− 3.34
SD
CV
1 −−
−−
0.034
4.0
2 −−
−−
0.050
2.3
3 −−
−−
0.065
2.0
# Points −− 817 −− 804 −− 818
# Labs 2 2 2

Mean −− 0.840 −− 2.06 −− 3.30
SD
CV
1 −−
−−
0.045
5.4
2 −−
−−
0.000
0.0
3 −−
−−
0.131
4.0
# Points −− 684 −− 66 −− 684
# Labs 6 1 6

Mean −− 0.858 −− −− −− 3.33
SD
CV
1 −−
−−
0.038
4.4
2 −−
−−
−−
−−
3 −−
−−
0.099
3.0
# Points −− 456 −− −− −− 450
# Labs 2 2

Mean −− 0.922 −− 2.26 −− 3.65
SD
CV
1 −−
−−
0.055
6.0
2 −−
−−
0.059
2.6
3 −−
−−
0.069
1.9
# Points −− 452 −− 457 −− 474
# Labs 3 3 3

Mean 0.790 0.847 −− 2.13 3.35 3.37
SD
CV
1 0.049
6.3
0.049
5.8
2 −−
−−
0.073
3.4
3 0.082
2.5
0.132
3.9
# Points 241 4104 −− 2941 239 4260
# Labs 1 19 12 1 20
Magnesium Chlorophosphonazo III mg/dL

Mean 0.960 1.00 −− 2.56 4.07 4.08
SD
CV
1 0.060
6.3
0.042
4.2
2 −−
−−
0.050
2.0
3 0.100
2.5
0.088
2.1
# Points 241 1696 −− 1614 239 1835
# Labs 1 7 6 1 8
Roche cobas 6000/c 311 • Alternate Calibration

Mean −− 1.10 −− −− −− 4.10
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− 1 −− −− −− 1
# Labs 1 1
Roche cobas 8000

Mean −− 1.03 −− 2.57 −− 4.07
SD
CV
1 −−
−−
0.042
4.0
2 −−
−−
0.060
2.3
3 −−
−−
0.079
2.0
# Points −− 817 −− 804 −− 818
# Labs 2 2 2
Magnesium Chlorophosphonazo III mg/dL

Mean −− 1.02 −− 2.50 −− 4.01
SD
CV
1 −−
−−
0.055
5.4
2 −−
−−
0.000
0.0
3 −−
−−
0.159
4.0
# Points −− 684 −− 66 −− 684
# Labs 6 1 6

Mean −− 1.04 −− −− −− 4.04
SD
CV
1 −−
−−
0.046
4.4
2 −−
−−
−−
−−
3 −−
−−
0.121
3.0
# Points −− 456 −− −− −− 450
# Labs 2 2

Mean −− 1.12 −− 2.75 −− 4.44
SD
CV
1 −−
−−
0.067
6.0
2 −−
−−
0.072
2.6
3 −−
−−
0.084
1.9
# Points −− 452 −− 457 −− 474
# Labs 3 3 3

Mean 0.960 1.03 −− 2.59 4.07 4.10
SD
CV
1 0.060
6.3
0.059
5.8
2 −−
−−
0.089
3.4
3 0.100
2.5
0.160
3.9
# Points 241 4104 −− 2941 239 4260
# Labs 1 19 12 1 20
Magnesium Enzymatic mEq/L

Mean 0.792 0.799 2.02 2.04 3.31 3.31
SD
CV
1 0.030
3.8
0.037
4.7
2 0.050
2.5
0.063
3.1
3 0.080
2.4
0.089
2.7
# Points 1313 51628 847 26414 649 49676
# Labs 51 181 38 119 24 142

Mean 0.795 0.798 2.01 2.03 −− −−
SD
CV
1 0.025
3.1
0.033
4.2
2
0.029
1.4
0.041
2.0
3 −−
−−
−−
−−
# Points 79 490 78 491 −− −−
# Labs 3 3 3 3
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c Magnesium, REF 08P19

Mean −− 0.825 −− 2.01 −− 3.32
SD
CV
1 −−
−−
0.079
9.6
2 −−
−−
0.033
1.6
3 −−
−−
0.121
3.7
# Points −− 238 −− 54 −− 208
# Labs 2 1 1

Mean −− 0.777 −− 2.00 −− 3.33
SD
CV
1 −−
−−
0.037
4.8
2 −−
−−
0.154
7.7
3 −−
−−
0.482
14.5
# Points −− 8 −− 655 −− 660
# Labs 2 3 4

Mean −− 0.784 −− −− −− −−
SD
CV
1 −−
−−
0.026
3.3
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 76 −− −− −− −−
# Labs 1

Mean −− −− −− 2.08 −− 3.34
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.036
1.7
3 −−
−−
0.048
1.4
# Points −− −− −− 496 −− 476
# Labs 1 1
Magnesium Enzymatic mEq/L

Siemens ADVIA Chemistry Systems • Abbott ARCH MAG REF 03P68
Mean −− 0.553 −− 1.89 −− 3.29
SD
CV
1 −−
−−
0.089
16.2
−−
−−
2
0.095
5.0
3 −−
−−
0.117
3.5
# Points −− 138 −− 130 −− 135
# Labs 2 2 2

Mean 0.793 0.798 2.02 2.04 3.31 3.31
SD
CV
1 0.030
3.8
0.040
5.0
2 0.049
2.4
0.067
3.3
3 0.080
2.4
0.104
3.1
# Points 1392 52578 925 28240 649 51155
# Labs 54 191 41 129 24 150
Magnesium Enzymatic mg/dL

Mean 0.963 0.971 2.45 2.48 4.02 4.02
SD
CV
1 0.037
3.8
0.045
4.7
2 0.061
2.5
0.076
3.1
3 0.098
2.4
0.108
2.7
# Points 1313 51628 847 26414 649 49676
# Labs 51 181 38 119 24 142

Mean 0.966 0.970 2.45 2.47 −− −−
SD
CV
1 0.030
3.1
0.041
4.2
2
0.035
1.4
0.049
2.0
3 −−
−−
−−
−−
# Points 79 490 78 491 −− −−
# Labs 3 3 3 3
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c Magnesium, REF 08P19

Mean −− 1.00 −− 2.45 −− 4.03
SD
CV
1 −−
−−
0.096
9.6
2−−
−−
0.040
1.6
3 −−
−−
0.147
3.7
# Points −− 238 −− 54 −− 208
# Labs 2 1 1

Mean −− 0.945 −− 2.43 −− 4.05
SD
CV
1 −−
−−
0.045
4.8
2 −−
−−
0.188
7.7
3 −−
−−
0.586
14.5
# Points −− 8 −− 655 −− 660
# Labs 2 3 4

Mean −− 0.953 −− −− −− −−
SD
CV
1 −−
−−
0.032
3.3
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 76 −− −− −− −−
# Labs 1

Mean −− −− −− 2.52 −− 4.06
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.044
1.7
3 −−
−−
0.058
1.4
# Points −− −− −− 496 −− 476
# Labs 1 1
Siemens ADVIA Chemistry Systems • Abbott ARCH MAG REF 03P68

Mean −− 0.672 −− 2.30 −− 4.00
SD
CV
1 −−
−−
0.109
16.2
−−
−−
2
0.116
5.0
3 −−
−−
0.142
3.5
# Points −− 138 −− 130 −− 135
# Labs 2 2 2

Mean 0.963 0.970 2.45 2.48 4.02 4.02
SD
CV
1 0.037
3.8
0.048
5.0
2 0.059
2.4
0.081
3.3
3 0.098
2.4
0.126
3.1
# Points 1392 52578 925 28240 649 51155
# Labs 54 191 41 129 24 150
Magnesium Formazan dye mEq/L

Mean 0.757 0.768 2.05 2.08 3.25 3.24
SD
CV
1 0.049
6.5
0.041
5.3
2 0.045
2.2
0.091
4.4
3 0.074
2.3
0.090
2.8
# Points 16 1254 35 997 47 1512
# Labs 1 9 2 5 2 8

Mean 0.766 0.800 2.08 2.08 −− 3.37
SD
CV
1 0.025
3.3
0.061
7.7
2 0.032
1.6
0.047
2.2
3 −−
−−
0.091
2.7
# Points 53 671 54 494 −− 174
# Labs 2 3 2 2 1

Mean −− 0.832 −− 2.10 −− 3.26
SD
CV
1 −−
−−
0.028
3.3
2 −−
−−
0.067
3.2
3 −−
−−
0.063
1.9
# Points −− 523 −− 241 −− 586
# Labs 2 4 6

Mean −− 0.828 −− 2.13 −− 3.23
SD
CV
1 −−
−−
0.058
7.1
2 −−
−−
0.040
1.9
3 −−
−−
0.080
2.5
# Points −− 1017 −− 126 −− 1052
# Labs 8 3 7

Mean 0.753 0.751 2.06 2.05 3.28 3.27
SD
CV
1 0.047
6.3
0.049
6.5
2 0.071
3.4
0.071
3.5
3 0.098
3.0
0.104
3.2
# Points 545 28619 237 13072 477 27950
# Labs 22 141 9 62 19 128

Mean 0.823 0.745 −− 2.03 3.17 3.24
SD
CV
1 0.000
0.0
0.044
5.9
2 −−
−−
0.072
3.5
3 0.066
2.1
0.109
3.3
# Points 22 24893 −− 10228 22 24890
# Labs 1 128 56 1 124

Mean 0.756 0.752 2.09 2.08 3.27 3.29
SD
CV
1 0.046
6.1
0.037
4.9
2 0.049
2.3
0.070
3.4
3 0.140
4.3
0.102
3.1
# Points 185 6850 105 3547 196 6321
# Labs 12 62 7 30 10 51

Mean 0.770 0.770 2.06 2.06 3.26 3.26
SD
CV
1 0.042
5.5
0.041
5.3
2 0.052
2.5
0.049
2.4
3 0.090
2.8
0.101
3.1
# Points 630 1295 354 708 441 1036
# Labs 28 31 17 19 20 23

Mean −− 0.755 −− 2.08 −− 3.31
SD
CV
1 −−
−−
0.034
4.6
2 −−
−−
0.033
1.6
3 −−
−−
0.083
2.5
# Points −− 684 −− 4 −− 685
# Labs 2 1 2

Mean −− 0.760 −− −− −− 3.18
SD
CV
1 −−
−−
0.036
4.7
2 −−
−−
−−
−−
3 −−
−−
0.087
2.7
# Points −− 54 −− −− −− 54
# Labs 1 1
Magnesium Formazan dye mEq/L

Mean −− 0.863 −− −− −− 3.20
SD
CV
1 −−
−−
0.037
4.3
2 −−
−−
−−
−−
3 −−
−−
0.082
2.6
# Points −− 84 −− −− −− 75
# Labs 1 1

Mean −− 0.885 −− −− −− 3.29
SD
CV
1 −−
−−
0.041
4.7
2 −−
−−
−−
−−
3 −−
−−
0.073
2.2
# Points −− 157 −− −− −− 154
# Labs 1 1

Mean −− 0.881 −− −− −− 3.23
SD
CV
1 −−
−−
0.025
2.8
2 −−
−−
−−
−−
3 −−
−−
0.067
2.1
# Points −− 71 −− −− −− 70
# Labs 1 1

Mean −− 0.820 −− −− −− 3.24
SD
CV
1 −−
−−
0.034
4.2
2 −−
−−
−−
−−
3 −−
−−
0.064
2.0
# Points −− 115 −− −− −− 101
# Labs 1 1

Mean −− 0.790 −− −− −− 3.09
SD
CV
1 −−
−−
0.024
3.1
2 −−
−−
−−
−−
3 −−
−−
0.038
1.2
# Points −− 112 −− −− −− 109
# Labs 1 1

Mean −− 0.713 −− −− −− 3.16
SD
CV
1 −−
−−
0.021
2.9
2 −−
−−
−−
−−
3 −−
−−
0.046
1.4
# Points −− 120 −− −− −− 115
# Labs 2 2
Method Group • Formazan dye

Mean 0.762 0.753 2.07 2.05 3.27 3.26
SD
CV
1 0.045
5.9
0.049
6.5
2 0.058
2.8
0.074
3.6
3 0.103
3.2
0.107
3.3
# Points 1451 67040 785 29417 1183 65406
# Labs 66 397 37 183 52 361
Magnesium Formazan dye mg/dL

Mean 0.920 0.933 2.49 2.52 3.95 3.94
SD
CV
1 0.060
6.5
0.050
5.3
2 0.055
2.2
0.110
4.4
3 0.089
2.3
0.110
2.8
# Points 16 1254 35 997 47 1512
# Labs 1 9 2 5 2 8

Mean 0.931 0.972 2.53 2.53 −− 4.10
SD
CV
1 0.031
3.3
0.075
7.7
2 0.039
1.6
0.057
2.2
3 −−
−−
0.111
2.7
# Points 53 671 54 494 −− 174
# Labs 2 3 2 2 1

Mean −− 1.01 −− 2.55 −− 3.96
SD
CV
1 −−
−−
0.034
3.3
2 −−
−−
0.081
3.2
3 −−
−−
0.077
1.9
# Points −− 523 −− 241 −− 586
# Labs 2 4 6

Mean −− 1.01 −− 2.59 −− 3.93
SD
CV
1 −−
−−
0.071
7.1
2 −−
−−
0.049
1.9
3 −−
−−
0.098
2.5
# Points −− 1017 −− 126 −− 1052
# Labs 8 3 7

Mean 0.915 0.913 2.50 2.50 3.99 3.97
SD
CV
1 0.058
6.3
0.059
6.5
2 0.086
3.4
0.087
3.5
3 0.119
3.0
0.127
3.2
# Points 545 28619 237 13072 477 27950
# Labs 22 141 9 62 19 128

Mean 1.00 0.906 −− 2.47 3.85 3.94
SD
CV
1 0.000
0.0
0.054
5.9
2 −−
−−
0.087
3.5
3 0.080
2.1
0.132
3.3
# Points 22 24893 −− 10228 22 24890
# Labs 1 128 56 1 124

Mean 0.919 0.913 2.54 2.53 3.97 4.00
SD
CV
1 0.056
6.1
0.045
4.9
2 0.059
2.3
0.085
3.4
3 0.170
4.3
0.124
3.1
# Points 185 6850 105 3547 196 6321
# Labs 12 62 7 30 10 51

Mean 0.936 0.936 2.51 2.51 3.97 3.96
SD
CV
1 0.051
5.5
0.049
5.3
2 0.063
2.5
0.060
2.4
3 0.110
2.8
0.122
3.1
# Points 630 1295 354 708 441 1036
# Labs 28 31 17 19 20 23

Mean −− 0.917 −− 2.53 −− 4.03
SD
CV
1 −−
−−
0.042
4.6
2 −−
−−
0.040
1.6
3 −−
−−
0.100
2.5
# Points −− 684 −− 4 −− 685
# Labs 2 1 2

Mean −− 0.924 −− −− −− 3.87
SD
CV
1 −−
−−
0.043
4.7
2 −−
−−
−−
−−
3 −−
−−
0.106
2.7
# Points −− 54 −− −− −− 54
# Labs 1 1

Mean −− 1.05 −− −− −− 3.88
SD
CV
1 −−
−−
0.045
4.3
2 −−
−−
−−
−−
3 −−
−−
0.100
2.6
# Points −− 84 −− −− −− 75
# Labs 1 1

Mean −− 1.08 −− −− −− 4.00
SD
CV
1 −−
−−
0.050
4.7
2 −−
−−
−−
−−
3 −−
−−
0.088
2.2
# Points −− 157 −− −− −− 154
# Labs 1 1

Mean −− 1.07 −− −− −− 3.93
SD
CV
1 −−
−−
0.030
2.8
2 −−
−−
−−
−−
3 −−
−−
0.082
2.1
# Points −− 71 −− −− −− 70
# Labs 1 1

Mean −− 0.997 −− −− −− 3.94
SD
CV
1 −−
−−
0.042
4.2
2 −−
−−
−−
−−
3 −−
−−
0.078
2.0
# Points −− 115 −− −− −− 101
# Labs 1 1

Mean −− 0.960 −− −− −− 3.75
SD
CV
1 −−
−−
0.030
3.1
2 −−
−−
−−
−−
3 −−
−−
0.046
1.2
# Points −− 112 −− −− −− 109
# Labs 1 1

Mean −− 0.867 −− −− −− 3.84
SD
CV
1 −−
−−
0.025
2.9
2 −−
−−
−−
−−
3 −−
−−
0.056
1.4
# Points −− 120 −− −− −− 115
# Labs 2 2
Method Group • Formazan dye

Mean 0.927 0.916 2.51 2.49 3.97 3.97
SD
CV
1 0.055
5.9
0.060
6.5
2 0.071
2.8
0.089
3.6
3 0.126
3.2
0.130
3.3
# Points 1451 67040 785 29417 1183 65406
# Labs 66 397 37 183 52 361
Magnesium Imidazole blue mEq/L

Mean −− 0.757 −− −− −− −−
SD
CV
1 −−
−−
0.022
2.9
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 25 −− −− −− −−
# Labs 1
Fuji Dri−Chem Series • Fuji Dri−Chem Mg−PIII, REF 9903212

Mean −− 0.782 −− 2.18 −− −−
SD
CV
1 −−
−−
0.048
6.1
2 −−
−−
0.058
2.7
3 −−
−−
−−
−−
# Points −− 4 −− 2 −− −−
# Labs 1 2
Method Group • Imidazole blue

Mean −− 0.760 −− 2.18 −− −−
SD
CV
1 −−
−−
0.027
3.6
2 −−
−−
0.058
2.7
3 −−
−−
−−
−−
# Points −− 29 −− 2 −− −−
# Labs 2 2
Magnesium Imidazole blue mg/dL

Mean −− 0.920 −− −− −− −−
SD
CV
1 −−
−−
0.027
2.9
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 25 −− −− −− −−
# Labs 1
Fuji Dri−Chem Series • Fuji Dri−Chem Mg−PIII, REF 9903212

Mean −− 0.950 −− 2.65 −− −−
SD
CV
1 −−
−−
0.058
6.1
2 −−
−−
0.071
2.7
3 −−
−−
−−
−−
# Points −− 4 −− 2 −− −−
# Labs 1 2
Magnesium Imidazole blue mg/dL

Method Group • Imidazole blue
Mean −− 0.924 −− 2.65 −− −−
SD
CV
1 −−
−−
0.033
3.6
2 −−
−−
0.071
2.7
3 −−
−−
−−
−−
# Points −− 29 −− 2 −− −−
# Labs 2 2
Magnesium Magon dye mEq/L

Mean −− 0.854 −− −− −− 3.41
SD
CV
1 −−
−−
0.078
9.2
2 −−
−−
−−
−−
3 −−
−−
0.129
3.8
# Points −− 595 −− −− −− 650
# Labs 2 2

Mean −− 0.034 −− −− −− 0.144
SD
CV
1 −−
−−
0.002
5.2
2 −−
−−
−−
−−
3 −−
−−
0.003
2.2
# Points −− 547 −− −− −− 548
# Labs 1 1
Method Group • Magon dye

Mean −− 0.461 −− −− −− 1.92
SD
CV
1 −−
−−
0.414
89.7
2 −−
−−
−−
−−
3 −−
−−
1.63
85.1
# Points −− 1142 −− −− −− 1198
# Labs 3 3
Magnesium Magon dye mg/dL

Mean −− 1.04 −− −− −− 4.15
SD
CV
1 −−
−−
0.095
9.2
2 −−
−−
−−
−−
3 −−
−−
0.157
3.8
# Points −− 595 −− −− −− 650
# Labs 2 2

Mean −− 0.041 −− −− −− 0.175
SD
CV
1 −−
−−
0.002
5.2
2 −−
−−
−−
−−
3 −−
−−
0.004
2.2
# Points −− 547 −− −− −− 548
# Labs 1 1
Method Group • Magon dye

Mean −− 0.560 −− −− −− 2.33
SD
CV
1 −−
−−
0.503
89.7
2 −−
−−
−−
−−
3 −−
−−
1.98
85.1
# Points −− 1142 −− −− −− 1198
# Labs 3 3
Magnesium Methylthymol blue mEq/L

Mean 0.800 0.724 2.02 1.97 3.28 3.21
SD
CV
1 0.040
5.0
0.065
9.0
2 0.040
2.0
0.081
4.1
3 0.060
1.8
0.120
3.7
# Points 38 865 38 865 38 864
# Labs 1 2 1 2 1 2

Mean 0.833 0.824 −− −− 3.34 3.31
SD
CV
1 0.028
3.3
0.025
3.1
2 −−
−−
−−
−−
3 0.055
1.6
0.070
2.1
# Points 32 701 −− −− 32 652
# Labs 1 3 1 3
Magnesium Methylthymol blue mEq/L

Mean 0.831 0.872 2.08 2.14 3.31 3.39
SD
CV
1 0.043
5.2
0.054
6.2
2 0.060
2.9
0.076
3.5
3 0.081
2.4
0.106
3.1
# Points 63 698 61 701 63 700
# Labs 2 2 2 2 2 2

Mean 0.736 0.749 2.05 2.03 3.30 3.34
SD
CV
1 0.054
7.4
0.073
9.8
2 0.074
3.6
0.084
4.2
3 0.088
2.7
0.111
3.3
# Points 1521 89020 344 13660 1431 82877
# Labs 49 220 11 45 46 203

Mean 0.829 0.835 2.12 2.16 3.45 3.49
SD
CV
1 0.075
9.1
0.077
9.2
2 0.075
3.5
0.085
4.0
3 0.100
2.9
0.110
3.2
# Points 2772 232K 876 69448 2383 214K
# Labs 85 460 30 132 75 438

Mean 0.797 0.811 2.10 2.14 3.39 3.45
SD
CV
1 0.081
10.2
0.085
10.5
2 0.081
3.8
0.098
4.6
3 0.118
3.5
0.130
3.8
# Points 4426 324K 1319 84674 3947 299K
# Labs 138 687 44 181 125 648
Magnesium Methylthymol blue mg/dL

Mean 0.972 0.880 2.46 2.40 3.99 3.90
SD
CV
1 0.049
5.0
0.079
9.0
2 0.049
2.0
0.098
4.1
3 0.073
1.8
0.146
3.7
# Points 38 865 38 865 38 864
# Labs 1 2 1 2 1 2

Mean 1.01 1.00 −− −− 4.06 4.02
SD
CV
1 0.034
3.3
0.031
3.1
2 −−
−−
−−
−−
3 0.067
1.6
0.085
2.1
# Points 32 701 −− −− 32 652
# Labs 1 3 1 3

Mean 1.01 1.06 2.52 2.60 4.02 4.13
SD
CV
1 0.052
5.2
0.066
6.2
2 0.073
2.9
0.092
3.5
3 0.099
2.4
0.129
3.1
# Points 63 698 61 701 63 700
# Labs 2 2 2 2 2 2

Mean 0.894 0.911 2.49 2.47 4.01 4.06
SD
CV
1 0.066
7.4
0.089
9.8
2 0.089
3.6
0.103
4.2
3 0.107
2.7
0.135
3.3
# Points 1521 89020 344 13660 1431 82877
# Labs 49 220 11 45 46 203

Mean 1.01 1.01 2.58 2.62 4.19 4.24
SD
CV
1 0.091
9.1
0.094
9.2
2 0.091
3.5
0.104
4.0
3 0.122
2.9
0.134
3.2
# Points 2772 232K 876 69448 2383 214K
# Labs 85 460 30 132 75 438

Mean 0.969 0.986 2.55 2.60 4.12 4.19
SD
CV
1 0.098
10.2
0.103
10.5
2 0.098
3.8
0.119
4.6
3 0.143
3.5
0.158
3.8
# Points 4426 324K 1319 84674 3947 299K
# Labs 138 687 44 181 125 648
Magnesium Xylidyl blue mEq/L

Mean 0.780 0.815 2.05 2.08 3.39 3.38
SD
CV
1 0.044
5.7
0.052
6.4
2 0.060
2.9
0.070
3.3
3 0.145
4.3
0.140
4.1
# Points 95 2018 98 2215 96 2313
# Labs 6 9 6 11 6 12

Mean 0.880 0.839 2.10 2.11 3.34 3.34
SD
CV
1 0.040
4.5
0.040
4.8
2 0.040
1.9
0.051
2.4
3 0.080
2.4
0.075
2.2
# Points 21 427 22 474 22 472
# Labs 1 1 1 1 1 1

Mean −− −− −− 1.90 −− 2.94
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.210
11.0
3 −−
−−
0.311
10.6
# Points −− −− −− 406 −− 402
# Labs 2 2

Mean 0.815 0.823 2.06 2.07 3.31 3.33
SD
CV
1 0.038
4.7
0.036
4.4
2 0.060
2.9
0.068
3.3
3 0.096
2.9
0.103
3.1
# Points 2037 104K 1837 80993 1188 110K
# Labs 68 291 58 223 39 274

Mean −− 0.832 −− 2.09 −− 3.41
SD
CV
1 −−
−−
0.034
4.1
2 −−
−−
0.075
3.6
3 −−
−−
0.120
3.5
# Points −− 532 −− 818 −− 532
# Labs 4 6 4

Mean −− 0.837 −− −− −− 3.35
SD
CV
1 −−
−−
0.067
8.0
2 −−
−−
−−
−−
3 −−
−−
0.134
4.0
# Points −− 218 −− −− −− 218
# Labs 1 1

Mean 0.860 0.864 2.12 2.11 3.32 3.32
SD
CV
1 0.031
3.6
0.033
3.8
2 0.073
3.4
0.071
3.4
3 0.107
3.2
0.119
3.6
# Points 56 644 56 648 56 646
# Labs 2 2 2 2 2 2

Mean −− −− 2.16 2.06 3.34 3.15
SD
CV
1 −−
−−
−−
−−
2 0.060
2.8
0.098
4.8
3 0.080
2.4
0.146
4.6
# Points −− −− 5 718 4 718
# Labs 1 2 1 2

Mean −− −− 2.11 2.09 3.22 3.16
SD
CV
1 −−
−−
−−
−−
2 0.106
5.0
0.131
6.3
3 0.164
5.1
0.189
6.0
# Points −− −− 42 216 40 217
# Labs 3 3 3 3

Mean −− −− 4.70 5.00 −− −−
SD
CV
1 −−
−−
−−
−−
2 0.287
6.1
0.653
13.1
3 −−
−−
−−
−−
# Points −− −− 10 25 −− −−
# Labs 1 1

ERBA XL−640
Mean −− 1.10 −− 2.29 −− −−
SD
CV
1 −−
−−
0.217
19.7
2 −−
−−
0.256
11.2
3 −−
−−
−−
−−
# Points −− 18 −− 44 −− −−
# Labs 1 1

Mean −− 0.884 −− 2.13 −− 3.39
SD
CV
1 −−
−−
0.073
8.3
2 −−
−−
0.143
6.7
3 −−
−−
0.202
6.0
# Points −− 4442 −− 2844 −− 4533
# Labs 11 7 11

Mean −− 0.799 −− −− −− 3.32
SD
CV
1 −−
−−
0.020
2.5
2 −−
−−
−−
−−
3 −−
−−
0.065
2.0
# Points −− 89 −− −− −− 90
# Labs 1 1

Mean −− 0.827 −− −− −− 3.24
SD
CV
1 −−
−−
0.058
7.0
2 −−
−−
−−
−−
3 −−
−−
0.123
3.8
# Points −− 19 −− −− −− 19
# Labs 1 1
INCstar/Clinical Assays 155A

Mean −− 0.889 −− 3.55 −− −−
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
0.000
0.0
3 −−
−−
−−
−−
# Points −− 1 −− 1 −− −−
# Labs 1 1
Mindray BS Series
Mean −− 0.914 −− 2.21 −− 3.43
SD
CV
1 −−
−−
0.034
3.7
2 −−
−−
0.063
2.9
3 −−
−−
0.091
2.7
# Points −− 140 −− 385 −− 386
# Labs 2 2 2

Mean −− −− −− 2.07 −− 3.18
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.181
8.7
3 −−
−−
0.273
8.6
# Points −− −− −− 257 −− 260
# Labs 2 2
RANDOX RX daytona
Mean −− −− −− 1.89 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.061
3.3
3 −−
−−
−−
−−
# Points −− −− −− 10 −− −−
# Labs 1
RANDOX RX imola
Mean 0.895 0.936 2.19 2.20 −− −−
SD
CV
1 0.034
3.8
0.074
7.9
2 0.041
1.9
0.055
2.5
3 −−
−−
−−
−−
# Points 26 223 24 193 −− −−
# Labs 1 1 1 1

Mean 0.834 0.828 2.11 2.10 3.37 3.35
SD
CV
1 0.038
4.6
0.039
4.6
2 0.080
3.8
0.058
2.8
3 0.077
2.3
0.096
2.9
# Points 1260 40634 313 19909 1175 40632
# Labs 30 121 10 60 27 120

Roche cobas 8000
Mean 0.842 0.838 2.18 2.12 3.37 3.36
SD
CV
1 0.028
3.3
0.033
3.9
2 0.040
1.8
0.050
2.4
3 0.058
1.7
0.065
1.9
# Points 646 38651 64 17783 700 43947
# Labs 13 57 1 36 14 69
Roche cobas 8000 • Roche MG2, REF 08058016

Mean −− 0.866 −− −− −− 3.42
SD
CV
1 −−
−−
0.030
3.4
2 −−
−−
−−
−−
3 −−
−−
0.034
1.0
# Points −− 263 −− −− −− 462
# Labs 2 2

Mean 0.842 0.845 2.13 2.14 3.41 3.41
SD
CV
1 0.023
2.7
0.026
3.1
2 0.041
1.9
0.047
2.2
3 0.050
1.5
0.062
1.8
# Points 278 7714 238 6658 127 6725
# Labs 7 21 5 15 5 19
Roche cobas c 303/503 • Roche MG2, REF 08058016

Mean 0.860 0.861 2.13 2.14 3.41 3.39
SD
CV
1 0.029
3.3
0.052
6.1
2 0.026
1.2
0.029
1.3
3 0.064
1.9
0.087
2.6
# Points 374 9510 159 1914 239 9449
# Labs 11 32 4 10 8 29

Mean 0.800 0.850 2.00 2.13 3.27 3.34
SD
CV
1 0.120
15.0
0.045
5.3
2 0.107
5.3
0.073
3.4
3 0.143
4.4
0.083
2.5
# Points 31 1030 62 1402 62 491
# Labs 1 4 2 4 2 4

Mean 0.836 0.841 2.06 2.08 3.30 3.27
SD
CV
1 0.035
4.2
0.041
4.8
2 0.082
4.0
0.088
4.2
3 0.114
3.5
0.098
3.0
# Points 68 1817 30 756 68 1981
# Labs 2 5 1 1 2 5

Mean 0.860 0.893 2.14 2.05 3.42 3.17
SD
CV
1 0.020
2.3
0.124
13.9
2 0.020
0.9
0.167
8.1
3 0.040
1.2
0.258
8.1
# Points 31 822 31 821 31 817
# Labs 1 3 1 3 1 3

Mean −− 0.884 −− 2.10 −− 3.30
SD
CV
1 −−
−−
0.032
3.6
2 −−
−−
0.054
2.6
3 −−
−−
0.089
2.7
# Points −− 633 −− 632 −− 631
# Labs 2 2 2
Mean −− 1.04 −− 2.18 −− 3.44
SD
CV
1 −−
−−
0.135
13.0
2 −−
−−
0.180
8.3
3 −−
−−
0.215
6.3
# Points −− 231 −− 562 −− 539
# Labs 1 3 2

Mean −− −− −− 1.95 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.215
11.1
3 −−
−−
−−
−−
# Points −− −− −− 23 −− −−
# Labs 1

Mean 0.821 0.801 2.09 2.05 3.30 3.27
SD
CV
1 0.064
7.8
0.057
7.2
2 0.093
4.5
0.064
3.1
3 0.170
5.2
0.099
3.0
# Points 113 14034 105 10696 105 13820
# Labs 4 33 4 29 4 32

Mean 0.825 0.788 2.07 2.03 3.38 3.31
SD
CV
1 0.030
3.6
0.050
6.3
2 0.040
2.0
0.071
3.5
3 0.114
3.4
0.106
3.2
# Points 567 31614 455 16520 261 24163
# Labs 17 88 15 62 10 70
Siemens Atellica CH Analyzer • Siemens Atellica CH Mg, REF 11097612

Mean −− 0.813 −− −− −− 3.35
SD
CV
1 −−
−−
0.025
3.1
−−
−−
2 −−
−−
3 −−
−−
0.048
1.4
# Points −− 223 −− −− −− 215
# Labs 2 2

Mean −− −− 2.06 2.06 −− −−
SD
CV
1 −−
−−
−−
−−
2 0.050
2.4
0.057
2.8
3 −−
−−
−−
−−
# Points −− −− 20 28 −− −−
# Labs 1 1
Toshiba−TBA
Mean −− −− −− −− −− 3.39
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
0.133
3.9
# Points −− −− −− −− −− 83
# Labs 1

Mean −− 0.872 −− 2.15 −− 3.30
SD
CV
1 −−
−−
0.045
5.2
2 −−
−−
0.072
3.3
3 −−
−−
0.108
3.3
# Points −− 232 −− 230 −− 231
# Labs 1 1 1
Method Group • Xylidyl blue

Mean 0.829 0.824 2.09 2.08 3.35 3.34
SD
CV
1 0.040
4.8
0.047
5.7
2 0.155
7.4
0.084
4.1
3 0.098
2.9
0.107
3.2
# Points 5603 262K 3571 170K 4174 265K
# Labs 164 702 117 498 125 679
Magnesium Xylidyl blue mg/dL

Mean 0.948 0.990 2.50 2.53 4.12 4.11
SD
CV
1 0.054
5.7
0.064
6.4
2 0.073
2.9
0.085
3.3
3 0.176
4.3
0.170
4.1
# Points 95 2018 98 2215 96 2313
# Labs 6 9 6 11 6 12

Mean 1.07 1.02 2.55 2.56 4.06 4.06
SD
CV
1 0.049
4.5
0.049
4.8
2 0.049
1.9
0.062
2.4
3 0.097
2.4
0.091
2.2
# Points 21 427 22 474 22 472
# Labs 1 1 1 1 1 1

Mean −− −− −− 2.31 −− 3.57
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.255
11.0
3 −−
−−
0.379
10.6
# Points −− −− −− 406 −− 402
# Labs 2 2

Mean 0.991 1.00 2.50 2.52 4.02 4.05
SD
CV
1 0.047
4.7
0.044
4.4
2 0.073
2.9
0.082
3.3
3 0.116
2.9
0.125
3.1
# Points 2037 104K 1837 80993 1188 110K
# Labs 68 291 58 223 39 274

Mean −− 1.01 −− 2.54 −− 4.14
SD
CV
1 −−
−−
0.042
4.1
2 −−
−−
0.091
3.6
3 −−
−−
0.145
3.5
# Points −− 532 −− 818 −− 532
# Labs 4 6 4

Mean −− 1.02 −− −− −− 4.07
SD
CV
1 −−
−−
0.082
8.0
2 −−
−−
−−
−−
3 −−
−−
0.163
4.0
# Points −− 218 −− −− −− 218
# Labs 1 1

Mean 1.05 1.05 2.58 2.57 4.04 4.03
SD
CV
1 0.038
3.6
0.040
3.8
2 0.088
3.4
0.087
3.4
3 0.130
3.2
0.144
3.6
# Points 56 644 56 648 56 646
# Labs 2 2 2 2 2 2

Mean −− −− 2.63 2.50 4.06 3.83
SD
CV
1 −−
−−
−−
−−
2 0.073
2.8
0.119
4.8
3 0.097
2.4
0.177
4.6
# Points −− −− 5 718 4 718
# Labs 1 2 1 2

Mean −− −− 2.56 2.54 3.91 3.84
SD
CV
1 −−
−−
−−
−−
2 0.128
5.0
0.159
6.3
3 0.199
5.1
0.230
6.0
# Points −− −− 42 216 40 217
# Labs 3 3 3 3

Mean −− −− 5.71 6.08 −− −−
SD
CV
1 −−
−−
−−
−−
2 0.348
6.1
0.794
13.1
3 −−
−−
−−
−−
# Points −− −− 10 25 −− −−
# Labs 1 1
ERBA XL−640
Mean −− 1.34 −− 2.79 −− −−
SD
CV
1 −−
−−
0.264
19.7
2 −−
−−
0.311
11.2
3 −−
−−
−−
−−
# Points −− 18 −− 44 −− −−
# Labs 1 1

Mean −− 1.07 −− 2.59 −− 4.12
SD
CV
1 −−
−−
0.089
8.3
2 −−
−−
0.174
6.7
3 −−
−−
0.246
6.0
# Points −− 4442 −− 2844 −− 4533
# Labs 11 7 11

Mean −− 0.971 −− −− −− 4.03
SD
CV
1 −−
−−
0.024
2.5
2 −−
−−
−−
−−
3 −−
−−
0.079
2.0
# Points −− 89 −− −− −− 90
# Labs 1 1

Mean −− 1.01 −− −− −− 3.94
SD
CV
1 −−
−−
0.071
7.0
2 −−
−−
−−
−−
3 −−
−−
0.150
3.8
# Points −− 19 −− −− −− 19
# Labs 1 1
INCstar/Clinical Assays 155A

Mean −− 1.08 −− 4.31 −− −−
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
0.000
0.0
3 −−
−−
−−
−−
# Points −− 1 −− 1 −− −−
# Labs 1 1
Mindray BS Series
Mean −− 1.11 −− 2.68 −− 4.17
SD
CV
1 −−
−−
0.041
3.7
2 −−
−−
0.076
2.9
3 −−
−−
0.111
2.7
# Points −− 140 −− 385 −− 386
# Labs 2 2 2

Mean −− −− −− 2.51 −− 3.87
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.219
8.7
3 −−
−−
0.331
8.6
# Points −− −− −− 257 −− 260
# Labs 2 2
RANDOX RX daytona
Mean −− −− −− 2.29 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.075
3.3
3 −−
−−
−−
−−
# Points −− −− −− 10 −− −−
# Labs 1
RANDOX RX imola
Mean 1.09 1.14 2.66 2.67 −− −−
SD
CV
1 0.041
3.8
0.090
7.9
2 0.049
1.9
0.067
2.5
3 −−
−−
−−
−−
# Points 26 223 24 193 −− −−
# Labs 1 1 1 1

Mean 1.01 1.01 2.57 2.55 4.09 4.07
SD
CV
1 0.047
4.6
0.047
4.6
2 0.097
3.8
0.071
2.8
3 0.093
2.3
0.117
2.9
# Points 1260 40634 313 19909 1175 40632
# Labs 30 121 10 60 27 120
Roche cobas 8000

Mean 1.02 1.02 2.65 2.58 4.09 4.09
SD
CV
1 0.034
3.3
0.040
3.9
2 0.049
1.8
0.061
2.4
3 0.071
1.7
0.079
1.9
# Points 646 38651 64 17783 700 43947
# Labs 13 57 1 36 14 69
Roche cobas 8000 • Roche MG2, REF 08058016

Mean −− 1.05 −− −− −− 4.16
SD
CV
1 −−
−−
0.036
3.4
2 −−
−−
−−
−−
3 −−
−−
0.042
1.0
# Points −− 263 −− −− −− 462
# Labs 2 2

Mean 1.02 1.03 2.59 2.60 4.14 4.14
SD
CV
1 0.028
2.7
0.032
3.1
2 0.049
1.9
0.057
2.2
3 0.061
1.5
0.076
1.8
# Points 278 7714 238 6658 127 6725
# Labs 7 21 5 15 5 19

Roche cobas c 303/503 • Roche MG2, REF 08058016
Mean 1.05 1.05 2.58 2.60 4.14 4.12
SD
CV
1 0.035
3.3
0.063
6.1
2 0.031
1.2
0.035
1.3
3 0.078
1.9
0.105
2.6
# Points 374 9510 159 1914 239 9449
# Labs 11 32 4 10 8 29

Mean 0.972 1.03 2.43 2.59 3.97 4.06
SD
CV
1 0.146
15.0
0.055
5.3
2 0.130
5.3
0.089
3.4
3 0.174
4.4
0.101
2.5
# Points 31 1030 62 1402 62 491
# Labs 1 4 2 4 2 4

Mean 1.02 1.02 2.50 2.53 4.01 3.98
SD
CV
1 0.043
4.2
0.049
4.8
2 0.100
4.0
0.107
4.2
3 0.139
3.5
0.119
3.0
# Points 68 1817 30 756 68 1981
# Labs 2 5 1 1 2 5

Mean 1.05 1.09 2.60 2.50 4.16 3.86
SD
CV
1 0.024
2.3
0.151
13.9
2 0.024
0.9
0.203
8.1
3 0.049
1.2
0.313
8.1
# Points 31 822 31 821 31 817
# Labs 1 3 1 3 1 3

Mean −− 1.07 −− 2.56 −− 4.01
SD
CV
1 −−
−−
0.039
3.6
2 −−
−−
0.065
2.6
3 −−
−−
0.109
2.7
# Points −− 633 −− 632 −− 631
# Labs 2 2 2
Mean −− 1.26 −− 2.65 −− 4.18
SD
CV
1 −−
−−
0.164
13.0
2 −−
−−
0.219
8.3
3 −−
−−
0.262
6.3
# Points −− 231 −− 562 −− 539
# Labs 1 3 2

Mean −− −− −− 2.36 −− −−
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.262
11.1
3 −−
−−
−−
−−
# Points −− −− −− 23 −− −−
# Labs 1

Mean 0.998 0.973 2.54 2.49 4.01 3.97
SD
CV
1 0.077
7.8
0.070
7.2
2 0.113
4.5
0.077
3.1
3 0.207
5.2
0.121
3.0
# Points 113 14034 105 10696 105 13820
# Labs 4 33 4 29 4 32

Mean 1.00 0.957 2.52 2.46 4.10 4.02
SD
CV
1 0.036
3.6
0.061
6.3
2 0.049
2.0
0.087
3.5
3 0.138
3.4
0.129
3.2
# Points 567 31614 455 16520 261 24163
# Labs 17 88 15 62 10 70
Siemens Atellica CH Analyzer • Siemens Atellica CH Mg, REF 11097612

Mean −− 0.989 −− −− −− 4.07
SD
CV
1 −−
−−
0.030
3.1
2−−
−−
−−
−−
3 −−
−−
0.059
1.4
# Points −− 223 −− −− −− 215
# Labs 2 2

Mean −− −− 2.51 2.50 −− −−
SD
CV
1 −−
−−
−−
−−
2 0.061
2.4
0.070
2.8
3 −−
−−
−−
−−
# Points −− −− 20 28 −− −−
# Labs 1 1
Toshiba−TBA
Mean −− −− −− −− −− 4.12
SD
CV
1 −−
−−
−−
−−
2 −−
−−
−−
−−
3 −−
−−
0.161
3.9
# Points −− −− −− −− −− 83
# Labs 1

Mean −− 1.06 −− 2.62 −− 4.01
SD
CV
1 −−
−−
0.055
5.2
2 −−
−−
0.087
3.3
3 −−
−−
0.132
3.3
# Points −− 232 −− 230 −− 231
# Labs 1 1 1
Method Group • Xylidyl blue

Mean 1.01 1.00 2.54 2.53 4.07 4.06
SD
CV
1 0.049
4.8
0.057
5.7
2 0.189
7.4
0.103
4.1
3 0.119
2.9
0.130
3.2
# Points 5603 262K 3571 170K 4174 265K
# Labs 164 702 117 498 125 679
Osmolality Calculated mOsm/kg

Gonotec
Mean −− 300.8 −− −− −− −−
SD
CV
1 −−
−−
5.83
1.9
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 47 −− −− −− −−
# Labs 1

Mean −− 300.8 −− −− −− −−
SD
CV
1 −−
−−
5.83
1.9
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 47 −− −− −− −−
# Labs 1
Osmolality Freezing point mOsm/kg

Advanced Biomedical
Mean −− 310.6 −− 413.4 −− 541.0
SD
CV
1 −−
−−
3.47
1.1
2 −−
−−
5.47
1.3
3 −−
−−
5.05
0.9
# Points −− 19 −− 19 −− 18
# Labs 1 1 1
Advanced Instruments
Mean 309.1 307.5 412.7 412.2 542.6 540.5
SD
CV
1 4.39
1.4
3.49
1.1
2 2.53
0.6
8.30
2.0
3 7.13
1.3
6.05
1.1
# Points 670 28850 31 3379 589 23934
# Labs 22 94 1 13 20 78
Advanced Instruments • Roche TP2, REF 08058652

Mean −− 302.1 −− 407.6 −− −−
SD
CV
1 −−
−−
2.25
0.7
2 −−
−−
2.44
0.6
3 −−
−−
−−
−−
# Points −− 250 −− 250 −− −−
# Labs 1 1

Arkray/Menarini OSMO STATION Series
Mean −− 305.7 −− 413.2 −− 540.8
SD
CV
1 −−
−−
2.13
0.7
2 −−
−−
2.98
0.7
3 −−
−−
4.93
0.9
# Points −− 562 −− 399 −− 353
# Labs 7 2 4

Mean −− 314.4 −− −− −− 545.9
SD
CV
1 −−
−−
2.99
1.0
2 −−
−−
−−
−−
3 −−
−−
5.29
1.0
# Points −− 119 −− −− −− 116
# Labs 1 1

Mean −− 306.4 −− 415.4 −− 538.1
SD
CV
1 −−
−−
2.70
0.9
2 −−
−−
3.60
0.9
3 −−
−−
3.44
0.6
# Points −− 446 −− 52 −− 445
# Labs 3 2 3
Fiske Osmometer
Mean 310.4 309.8 −− 434.1 548.1 547.7
SD
CV
1 1.73
0.6
3.55
1.1
2 −−
−−
35.61
8.2
3 4.08
0.7
6.90
1.3
# Points 12 451 −− 143 12 464
# Labs 1 2 2 1 2
Fiske Osmometer • Advanced Biomedical

Mean 313.7 311.1 415.6 415.4 540.6 542.3
SD
CV
1 3.99
1.3
4.52
1.5
2 3.78
0.9
4.32
1.0
3 6.08
1.1
6.00
1.1
# Points 7 530 7 533 7 533
# Labs 1 1 1 1 1 1
Gonotec
Mean 311.5 309.9 417.8 415.3 542.6 542.5
SD
CV
1 6.40
2.1
5.16
1.7
2 8.58
2.1
4.00
1.0
3 6.12
1.1
5.50
1.0
# Points 10 298 8 203 8 140
# Labs 1 4 1 3 1 2
Gonotec OSMOMAT 3000

Mean 312.6 310.5 −− −− −− −−
SD
CV
1 1.26
0.4
1.91
0.6
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points 10 44 −− −− −− −−
# Labs 1 1
Precision Systems Osmometer

Mean 303.0 306.2 438.0 415.3 −− 538.6
SD
CV
1 0.000
0.0
3.28
1.1
2 0.000
0.0
19.63
4.7
3 −−
−−
5.94
1.1
# Points 1 1038 1 3 −− 1042
# Labs 1 6 1 1 5
Radiometer OSM−3
Mean −− 304.6 −− 410.5 −− 536.6
SD
CV
1 −−
−−
4.37
1.4
2 −−
−−
6.83
1.7
3 −−
−−
8.03
1.5
# Points −− 166 −− 152 −− 163
# Labs 1 1 1

Mean 305.0 306.8 −− −− 543.8 541.9
SD
CV
1 2.12
0.7
3.24
1.1
2 −−
−−
−−
−−
3 2.77
0.5
6.24
1.2
# Points 5 99 −− −− 5 99
# Labs 1 1 1 1

Method Group • Freezing point
Mean 309.2 307.6 414.6 413.1 542.1 540.7
SD
CV
1 4.37
1.4
3.61
1.2
2 5.77
1.4
10.05
2.4
3 7.39
1.4
6.20
1.1
# Points 746 33944 47 5133 652 28281
# Labs 29 127 4 27 25 103
Phenobarbital EIA µg/mL

Mean −− 8.19 −− 26.90 −− 55.89
SD
CV
1 −−
−−
0.383
4.7
2 −−
−−
1.06
3.9
3 −−
−−
2.35
4.2
# Points −− 134 −− 138 −− 135
# Labs 1 1 1

Mean 9.05 9.01 27.79 28.10 59.66 58.27
SD
CV
1 0.415
4.6
0.407
4.5
2 1.39
5.0
1.67
5.9
3 4.20
7.0
4.32
7.4
# Points 114 7017 51 1807 114 6942
# Labs 4 19 2 5 4 19
Beckman Coulter AU Series • Emit 2000 Phenobarbital, REF OSR4D229

Mean 8.77 8.96 27.91 28.66 −− 57.54
SD
CV
1 0.210
2.4
0.400
4.5
0.854
3.1
2 1.49
5.2
3 −−
−−
3.82
6.6
# Points 31 1185 31 627 −− 1050
# Labs 1 9 1 5 6
VITROS Microtip Series • Syva EMIT/EMIT II

Mean −− 9.04 −− −− −− 63.06
SD
CV
1 −−
−−
0.221
2.4
2 −−
−−
−−
−−
3 −−
−−
2.33
3.7
# Points −− 153 −− −− −− 154
# Labs 2 2

Mean 8.99 8.99 27.83 28.17 59.66 58.22
SD
CV
1 0.397
4.4
0.416
4.6
2 1.21
4.4
1.65
5.8
3 4.20
7.0
4.27
7.3
# Points 145 8489 82 2572 114 8281
# Labs 5 31 3 11 4 28
Phenobarbital Immunoturbidimetric µg/mL

Mean 8.28 8.47 26.24 27.25 −− 58.91
SD
CV
1 0.410
5.0
0.479
5.7
2 0.490
1.9
1.48
5.4
3 −−
−−
3.29
5.6
# Points 5 1201 5 1247 −− 553
# Labs 1 11 1 10 7

Mean −− 9.02 −− 28.68 −− 57.74
SD
CV
1 −−
−−
0.314
3.5
2 −−
−−
1.29
4.5
3 −−
−−
3.63
6.3
# Points −− 708 −− 691 −− 745
# Labs 3 3 3

Mean −− 9.45 −− 28.75 −− 61.91
SD
CV
1 −−
−−
0.587
6.2
2 −−
−−
1.69
5.9
3 −−
−−
3.43
5.5
# Points −− 1554 −− 222 −− 1547
# Labs 9 4 9
Phenobarbital Immunoturbidimetric µg/mL

Mean −− 23.40 −− −− −− −−
SD
CV
1 −−
−−
3.03
12.9
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 60 −− −− −− −−
# Labs 1

Mean −− 9.41 −− 28.81 −− 64.30
SD
CV
1 −−
−−
0.438
4.7
2 −−
−−
1.74
6.0
3 −−
−−
3.68
5.7
# Points −− 747 −− 743 −− 28
# Labs 4 4 2

Mean −− 9.59 −− 30.47 −− 61.43
SD
CV
1 −−
−−
0.519
5.4
2 −−
−−
0.847
2.8
3 −−
−−
1.61
2.6
# Points −− 2225 −− 1191 −− 2104
# Labs 8 3 6

Mean 10.29 10.23 −− 33.16 65.64 65.97
SD
CV
1 1.42
13.8
1.13
11.0
2 −−
−−
1.70
5.1
3 5.50
8.4
3.52
5.3
# Points 66 3141 −− 317 65 2949
# Labs 2 12 1 2 12

Mean 9.63 10.12 31.58 31.91 61.35 61.91
SD
CV
1 1.46
15.2
1.10
10.9
2 1.53
4.9
1.48
4.6
3 2.46
4.0
2.63
4.3
# Points 105 20264 15 6791 98 18458
# Labs 8 84 3 28 7 80

Mean 9.84 9.98 30.24 30.85 63.06 62.15
SD
CV
1 1.48
15.1
1.25
12.5
2 2.72
9.0
2.21
7.2
3 4.47
7.1
3.18
5.1
# Points 176 30497 20 11797 163 26980
# Labs 11 133 4 54 9 120
Phenobarbital KIMS (Roche) µg/mL

Mean 8.86 8.84 29.85 29.30 56.14 56.61
SD
CV
1 0.398
4.5
0.548
6.2
2 1.10
3.7
1.36
4.6
3 1.99
3.5
1.99
3.5
# Points 31 2430 30 796 30 2344
# Labs 1 9 1 5 1 9

Mean −− 9.60 −− −− −− 58.40
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− 1 −− −− −− 1
# Labs 1 1

Mean −− 9.55 −− 30.01 −− 58.81
SD
CV
1 −−
−−
0.332
3.5
2 −−
−−
0.745
2.5
3 −−
−−
1.59
2.7
# Points −− 547 −− 570 −− 613
# Labs 2 2 2
Roche cobas c 303/503 • Roche PHNO2, REF 08058580

Mean −− 9.74 −− −− −− 59.67
SD
CV
1 −−
−−
0.338
3.5
2 −−
−−
−−
−−
3 −−
−−
1.60
2.7
# Points −− 937 −− −− −− 956
# Labs 3 3
Phenobarbital KIMS (Roche) µg/mL

Mean 8.86 9.16 29.85 29.59 56.14 57.71
SD
CV
1 0.398
4.5
0.626
6.8
2 1.10
3.7
1.20
4.0
3 1.99
3.5
2.29
4.0
# Points 31 3914 30 1366 30 3913
# Labs 1 14 1 7 1 14
Phenytoin (Dilantin) Chemiluminescence µg/mL

Mean −− 4.49 −− −− −− 18.60
SD
CV
1 −−
−−
0.234
5.2
2 −−
−−
−−
−−
3 −−
−−
0.762
4.1
# Points −− 56 −− −− −− 55
# Labs 1 1

Mean −− 4.18 −− −− −− 20.55
SD
CV
1 −−
−−
0.435
10.4
2 −−
−−
−−
−−
3 −−
−−
0.968
4.7
# Points −− 273 −− −− −− 273
# Labs 1 1

Mean −− 4.23 −− −− −− 20.22
SD
CV
1 −−
−−
0.424
10.0
2 −−
−−
−−
−−
3 −−
−−
1.19
5.9
# Points −− 329 −− −− −− 328
# Labs 2 2
Phenytoin (Dilantin) EIA µg/mL

Mean 4.01 4.38 8.49 9.03 −− 18.14
SD
CV
1 0.190
4.7
0.342
7.8
2 0.410
4.8
0.527
5.8
3 −−
−−
0.863
4.8
# Points 5 1232 5 649 −− 581
# Labs 1 6 1 4 2

Mean 4.07 4.04 8.22 8.26 17.83 17.75
SD
CV
1 0.275
6.8
0.304
7.5
2 0.400
4.9
0.594
7.2
3 1.22
6.8
1.23
6.9
# Points 145 8865 51 2335 145 8725
# Labs 5 26 2 8 5 26
Beckman Coulter AU Series • Emit 2000 Phenytoin, REF OSR4A229

Mean 4.29 4.07 −− 8.41 −− 17.66
SD
CV
1 0.293
6.8
0.312
7.7
−−
−−
2
0.527
6.3
3 −−
−−
1.24
7.0
# Points 31 2527 −− 598 −− 2556
# Labs 1 14 5 12

Mean −− 4.01 −− 8.48 −− 17.67
SD
CV
1 −−
−−
0.478
11.9
2 −−
−−
0.783
9.2
3 −−
−−
1.81
10.3
# Points −− 1224 −− 785 −− 1218
# Labs 3 2 3

Mean −− 3.70 −− 7.90 −− −−
SD
CV
1 −−
−−
0.119
3.2
2 −−
−−
0.214
2.7
3 −−
−−
−−
−−
# Points −− 40 −− 39 −− −−
# Labs 1 1

Mean −− 3.97 −− −− −− 15.75
SD
CV
1 −−
−−
0.127
3.2
2 −−
−−
−−
−−
3 −−
−−
0.458
2.9
# Points −− 31 −− −− −− 31
# Labs 1 1

Mean −− 4.75 −− −− −− 16.70
SD
CV
1 −−
−−
0.498
10.5
2 −−
−−
−−
−−
3 −−
−−
0.607
3.6
# Points −− 122 −− −− −− 118
# Labs 1 1

Mean −− 5.24 −− −− −− 18.45
SD
CV
1 −−
−−
0.361
6.9
2 −−
−−
−−
−−
3 −−
−−
0.877
4.8
# Points −− 73 −− −− −− 72
# Labs 1 1

Mean −− 5.07 −− 8.32 −− 18.16
SD
CV
1 −−
−−
0.652
12.9
2 −−
−−
0.230
2.8
3 −−
−−
0.821
4.5
# Points −− 358 −− 86 −− 362
# Labs 3 1 3

Mean −− 4.94 −− 8.48 −− 18.02
SD
CV
1 −−
−−
0.628
12.7
2 −−
−−
0.226
2.7
3 −−
−−
0.470
2.6
# Points −− 115 −− 54 −− 113
# Labs 2 1 2

Mean −− 4.08 −− 7.92 −− 18.15
SD
CV
1 −−
−−
0.566
13.9
2 −−
−−
0.315
4.0
3 −−
−−
0.928
5.1
# Points −− 140 −− 83 −− 136
# Labs 3 1 3

Mean −− 3.82 −− 8.22 −− 17.20
SD
CV
1 −−
−−
0.425
11.1
2 −−
−−
0.326
4.0
3 −−
−−
0.651
3.8
# Points −− 519 −− 202 −− 517
# Labs 3 1 3

Mean −− 3.76 −− 7.87 −− 16.87
SD
CV
1 −−
−−
0.206
5.5
2 −−
−−
0.421
5.3
3 −−
−−
1.06
6.3
# Points −− 3679 −− 1849 −− 3628
# Labs 18 10 18

Mean −− 3.83 −− 7.62 −− 17.51
SD
CV
1 −−
−−
0.313
8.2
2 −−
−−
0.394
5.2
3 −−
−−
1.19
6.8
# Points −− 974 −− 760 −− 856
# Labs 9 5 7

Mean −− 3.93 −− 7.69 −− 18.07
SD
CV
1 −−
−−
0.231
5.9
2 −−
−−
0.427
5.6
3 −−
−−
1.10
6.1
# Points −− 515 −− 394 −− 437
# Labs 7 5 7

Mean −− 3.50 −− 7.70 −− 17.57
SD
CV
1 −−
−−
0.241
6.9
2 −−
−−
0.377
4.9
3 −−
−−
0.996
5.7
# Points −− 683 −− 767 −− 861
# Labs 8 5 8

Mean −− 3.68 −− 7.52 −− 17.00
SD
CV
1 −−
−−
0.230
6.3
2 −−
−−
0.339
4.5
3 −−
−−
0.980
5.8
# Points −− 399 −− 283 −− 316
# Labs 9 6 9

Mean 4.40 4.17 7.94 7.59 19.08 17.76
SD
CV
1 0.284
6.5
0.289
6.9
2 0.216
2.7
0.394
5.2
3 0.657
3.4
1.16
6.5
# Points 46 298 3 170 44 380
# Labs 3 6 1 3 2 5

Mean 4.19 4.19 7.75 7.75 15.88 15.88
SD
CV
1 0.149
3.6
0.149
3.6
2 0.176
2.3
0.176
2.3
3 1.000
6.3
1.000
6.3
# Points 34 34 30 30 6 6
# Labs 2 2 1 1 1 1

Mean 4.17 4.01 8.06 8.10 18.05 17.56
SD
CV
1 0.295
7.1
0.407
10.1
2 0.411
5.1
0.645
8.0
3 1.28
7.1
1.25
7.1
# Points 261 21888 89 9080 195 20823
# Labs 12 124 5 60 8 112
Phenytoin (Dilantin) Immunoturbidimetric µg/mL

Mean −− 4.10 −− 8.44 −− 17.77
SD
CV
1 −−
−−
0.257
6.3
2 −−
−−
0.442
5.2
3 −−
−−
1.02
5.7
# Points −− 650 −− 622 −− 683
# Labs 2 2 2

Mean −− 4.20 −− 9.02 −− 18.05
SD
CV
1 −−
−−
0.264
6.3
2 −−
−−
0.302
3.4
3 −−
−−
0.736
4.1
# Points −− 1936 −− 331 −− 1954
# Labs 10 4 10

Mean −− 3.76 −− 8.15 −− 17.54
SD
CV
1 −−
−−
0.444
11.8
2 −−
−−
0.760
9.3
3 −−
−−
0.901
5.1
# Points −− 694 −− 767 −− 45
# Labs 4 4 2

Mean −− 3.93 −− 8.80 −− 19.38
SD
CV
1 −−
−−
0.313
8.0
2 −−
−−
0.447
5.1
3 −−
−−
0.689
3.6
# Points −− 3261 −− 1464 −− 3158
# Labs 11 4 10

Mean 3.79 4.01 −− 8.95 20.13 20.25
SD
CV
1 0.449
11.8
0.553
13.8
2 −−
−−
0.726
8.1
3 1.07
5.3
1.10
5.4
# Points 113 7520 −− 450 121 7116
# Labs 4 27 3 4 25
Phenytoin (Dilantin) Immunoturbidimetric µg/mL

Mean 4.21 4.26 9.20 9.13 20.03 19.65
SD
CV
1 0.428
10.2
0.398
9.3
2 0.460
5.0
0.553
6.1
3 0.773
3.9
0.898
4.6
# Points 167 34963 20 7111 163 33537
# Labs 11 106 4 23 11 102

Mean 4.04 4.19 9.20 8.97 20.07 19.62
SD
CV
1 0.482
11.9
0.433
10.3
2 0.460
5.0
0.616
6.9
3 0.913
4.5
1.03
5.2
# Points 280 49742 20 11457 284 47210
# Labs 15 161 4 41 15 152
Phenytoin (Dilantin) KIMS (Roche) µg/mL

Mean 3.66 3.64 8.03 8.13 17.46 17.28
SD
CV
1 0.307
8.4
0.345
9.5
2 0.267
3.3
0.470
5.8
3 1.04
6.0
0.958
5.5
# Points 371 5318 30 1457 370 5250
# Labs 4 14 1 6 4 14

Mean −− 3.20 −− −− −− 17.80
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− 1 −− −− −− 1
# Labs 1 1

Mean −− 4.18 −− 8.69 −− 18.77
SD
CV
1 −−
−−
0.302
7.2
2 −−
−−
0.513
5.9
3 −−
−−
0.764
4.1
# Points −− 595 −− 652 −− 639
# Labs 2 2 2
Roche cobas c 303/503 • Roche PHENY2, REF 08058601/08445567

Mean −− 4.46 −− 9.30 −− 19.19
SD
CV
1 −−
−−
0.362
8.1
−−
−−
2 0.457
4.9
3 −−
−−
0.848
4.4
# Points −− 1454 −− 497 −− 1491
# Labs 6 2 6

Mean 3.66 3.85 8.03 8.49 17.46 17.80
SD
CV
1 0.307
8.4
0.482
12.5
2 0.267
3.3
0.662
7.8
3 1.04
6.0
1.23
6.9
# Points 371 7367 30 2606 370 7380
# Labs 4 22 1 10 4 22
Phospholipids Photometric, enzymatic mg/dL

Mean −− 131.6 −− −− −− 295.7
SD
CV
1 −−
−−
1.77
1.3
2 −−
−−
−−
−−
3 −−
−−
2.98
1.0
# Points −− 113 −− −− −− 113
# Labs 1 1
Beckman Coulter AU Series • Eiken Kagaku

Mean −− 128.8 −− −− −− 295.0
SD
CV
1 −−
−−
1.60
1.2
2 −−
−−
−−
−−
3 −−
−−
3.99
1.4
# Points −− 344 −− −− −− 344
# Labs 1 1
Phospholipids Photometric, enzymatic mg/dL

Siemens Atellica CH Analyzer • Fujifilmwako
Mean −− 131.7 −− −− −− 292.1
SD
CV
1 −−
−−
1.49
1.1
2 −−
−−
−−
−−
3 −−
−−
3.09
1.1
# Points −− 704 −− −− −− 704
# Labs 1 1
Method Group • Photometric, enzymatic

Mean −− 130.8 −− −− −− 293.3
SD
CV
1 −−
−−
2.04
1.6
2 −−
−−
−−
−−
3 −−
−−
3.69
1.3
# Points −− 1161 −− −− −− 1161
# Labs 3 3
Phosphorus AAS (Atomic Absorption Spectroscopy) mg/dL

Mean −− 0.000 −− −− −− 0.001
SD
CV
1 −−
−−
0.000
0.9
2 −−
−−
−−
−−
3 −−
−−
0.000
1.9
# Points −− 22 −− −− −− 22
# Labs 1 1

Mean −− −− −− 3.94 −− 7.22
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.100
2.5
3 −−
−−
0.127
1.8
# Points −− −− −− 595 −− 595
# Labs 3 3

Mean −− 0.000 −− −− −− 0.001
SD
CV
1 −−
−−
0.000
3.0
2 −−
−−
−−
−−
3 −−
−−
0.000
1.7
# Points −− 267 −− −− −− 244
# Labs 1 1

Mean −− 0.000 −− 3.94 −− 4.99
SD
CV
1 −−
−−
0.000
4.9
2 −−
−−
0.100
2.5
3 −−
−−
3.34
66.9
# Points −− 289 −− 595 −− 861
# Labs 2 3 5
Phosphorus Enzymatic mg/dL

Mean −− 1.82 −− 3.84 −− 7.17
SD
CV
1 −−
−−
0.096
5.3
2 −−
−−
0.050
1.3
3 −−
−−
0.151
2.1
# Points −− 189 −− 59 −− 175
# Labs 3 2 3

Mean −− 1.92 −− 3.97 −− 7.45
SD
CV
1 −−
−−
0.121
6.3
2 −−
−−
0.166
4.2
3 −−
−−
0.224
3.0
# Points −− 117 −− 264 −− 240
# Labs 2 3 3

Mean −− 2.13 −− −− −− −−
SD
CV
1 −−
−−
0.105
4.9
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 24 −− −− −− −−
# Labs 1
Phosphorus Enzymatic mg/dL

Mean −− 1.91 −− −− −− −−
SD
CV
1 −−
−−
0.024
1.2
2 −−
−−
−−
−−
3 −−
−−
−−
−−
# Points −− 62 −− −− −− −−
# Labs 1
RANDOX RX daytona
Mean 2.16 2.17 4.09 4.02 −− −−
SD
CV
1 0.097
4.5
0.128
5.9
2 0.145
3.5
0.177
4.4
3 −−
−−
−−
−−
# Points 10 206 10 144 −− −−
# Labs 1 1 1 1

Mean 2.01 1.88 3.90 3.80 7.34 7.24
SD
CV
1 0.062
3.1
0.104
5.5
2 0.062
1.6
0.153
4.0
3 0.093
1.3
0.255
3.5
# Points 15 269 14 268 14 268
# Labs 1 1 1 1 1 1

Mean −− 0.000 −− 0.000 −− −−
SD
CV
1 −−
−−
0.000
4.5
2 −−
−−
0.000
25.0
3 −−
−−
−−
−−
# Points −− 18 −− 10 −− −−
# Labs 1 1

Mean 2.25 2.25 4.17 4.17 7.58 7.58
SD
CV
1 0.036
1.6
0.036
1.6
2 0.067
1.6
0.067
1.6
3 0.126
1.7
0.126
1.7
# Points 4 4 4 4 4 4
# Labs 1 1 1 1 1 1

Mean 2.10 1.90 4.01 3.85 7.39 7.29
SD
CV
1 0.117
5.6
0.313
16.4
2 0.148
3.7
0.468
12.2
3 0.143
1.9
0.245
3.4
# Points 29 959 28 808 18 733
# Labs 3 13 3 11 2 10
Phosphorus Phosphomolybdate formation mg/dL

Dirui CS Series
Mean −− 1.86 −− 3.77 −− 7.13
SD
CV
1 −−
−−
0.102
5.5
2 −−
−−
0.138
3.7
3 −−
−−
0.170
2.4
# Points −− 208 −− 204 −− 200
# Labs 1 1 1

Mean 2.03 1.97 −− −− 7.45 7.40
SD
CV
1 0.050
2.5
0.075
3.8
2 −−
−−
−−
−−
3 0.089
1.2
0.147
2.0
# Points 72 1105 −− −− 72 988
# Labs 2 3 2 3

Mean −− 2.15 −− 4.13 −− 7.66
SD
CV
1 −−
−−
0.073
3.4
2 −−
−−
0.076
1.8
3 −−
−−
0.100
1.3
# Points −− 198 −− 294 −− 294
# Labs 1 1 1
Method Group • Phosphomolybdate formation

Mean 2.03 1.98 −− 3.98 7.45 7.42
SD
CV
1 0.050
2.5
0.111
5.6
2 −−
−−
0.204
5.1
3 0.089
1.2
0.208
2.8
# Points 72 1511 −− 498 72 1482
# Labs 2 5 2 2 5
Phosphorus Phosphomolybdate method mg/dL

Mean 1.93 1.91 3.80 3.81 7.28 7.24
SD
CV
1 0.069
3.6
0.066
3.4
2 0.104
2.7
0.105
2.8
3 0.132
1.8
0.139
1.9
# Points 1714 63304 1228 35276 869 60146
# Labs 70 222 56 149 39 179
Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c Phosphorus, REF 08P40

Mean −− 3.04 −− 5.30 −− −−
SD
CV
1 −−
−−
9.01
296.4
2 −−
−−
12.03
227.1
3 −−
−−
−−
−−
# Points −− 65 −− 65 −− −−
# Labs 1 1

Mean −− 2.05 −− 3.92 −− 7.16
SD
CV
1 −−
−−
0.068
3.3
2 −−
−−
0.099
2.5
3 −−
−−
0.140
2.0
# Points −− 267 −− 268 −− 267
# Labs 1 1 1

Mean 1.90 1.92 3.78 3.82 7.23 7.26
SD
CV
1 0.034
1.8
0.034
1.8
2
0.062
1.6
0.052
1.4
3 0.094
1.3
0.079
1.1
# Points 89 1340 89 1221 88 1338
# Labs 2 2 2 2 2 2

Mean 1.98 1.94 3.90 3.85 7.38 7.33
SD
CV
1 0.082
4.1
0.084
4.3
2 0.108
2.8
0.128
3.3
3 0.178
2.4
0.218
3.0
# Points 2031 105K 1848 82250 1152 110K
# Labs 67 308 58 237 37 290

Mean −− 1.93 −− 3.84 −− 7.24
SD
CV
1 −−
−−
0.082
4.2
2 −−
−−
0.124
3.2
3 −−
−−
0.198
2.7
# Points −− 650 −− 878 −− 652
# Labs 6 8 6

Mean −− 1.95 −− −− −− 7.38
SD
CV
1 −−
−−
0.058
3.0
2 −−
−−
−−
−−
3 −−
−−
0.311
4.2
# Points −− 210 −− −− −− 210
# Labs 1 1

Mean −− 1.90 −− 3.76 −− 6.92
SD
CV
1 −−
−−
0.055
2.9
2 −−
−−
0.077
2.0
3 −−
−−
0.145
2.1
# Points −− 291 −− 292 −− 290
# Labs 1 1 1

Mean 1.93 1.91 3.84 3.83 7.29 7.30
SD
CV
1 0.034
1.8
0.060
3.1
2 0.084
2.2
0.100
2.6
3 0.107
1.5
0.164
2.2
# Points 61 653 61 654 61 654
# Labs 2 2 2 2 2 2

Mean −− −− 3.72 3.85 7.24 7.33
SD
CV
1 −−
−−
−−
−−
2 0.031
0.8
0.111
2.9
3 0.062
0.9
0.231
3.2
# Points −− −− 5 724 4 725
# Labs 1 2 1 2

Mean −− 2.00 −− 4.23 −− 7.86
SD
CV
1 −−
−−
0.076
3.8
2 −−
−−
0.138
3.3
3 −−
−−
0.331
4.2
# Points −− 2055 −− 648 −− 2057
# Labs 9 3 9
Beckman Coulter UniCel DxC Series • Beckman Coulter PHOSm (Rgt 467868)
Mean −− 2.04 −− 4.29 −− −−
SD
CV
1 −−
−−
0.042
2.1
−−
−−
2 0.071
1.6
3 −−
−−
−−
−−
# Points −− 870 −− 746 −− −−
# Labs 2 2
Beckman Coulter UniCel DxC Series • Beckman Coulter PHS (Rgt A09426)
Mean 2.00 2.01 −− 4.06 7.79 7.67
SD
CV
1 0.037
1.8
0.075
3.7
2
−−
−−
0.136
3.3
3 0.191
2.5
0.241
3.1
# Points 59 5668 −− 751 63 5720
# Labs 2 21 6 2 20

Mean −− −− −− 3.92 −− 7.51
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.163
4.2
3 −−
−−
0.261
3.5
# Points −− −− −− 175 −− 175
# Labs 1 1
Dirui CS Series
Mean −− 1.98 −− 3.78 −− 6.92
SD
CV
1 −−
−−
0.054
2.7
2 −−
−−
0.074
2.0
3 −−
−−
0.096
1.4
# Points −− 527 −− 527 −− 527
# Labs 1 1 1

Mean −− −− 3.83 3.79 7.33 7.24
SD
CV
1 −−
−−
−−
−−
2 0.145
3.8
0.144
3.8
3 0.246
3.4
0.256
3.5
# Points −− −− 44 243 42 244
# Labs 3 3 3 3

Mean 1.91 1.94 3.73 3.81 6.73 6.59
SD
CV
1 0.073
3.8
0.127
6.5
2 0.130
3.5
0.235
6.2
3 0.245
3.6
0.232
3.5
# Points 44 450 29 351 5 44
# Labs 2 3 2 3 1 2
ERBA XL−640
Mean −− 2.29 −− 4.38 −− −−
SD
CV
1 −−
−−
0.273
11.9
2 −−
−−
0.363
8.3
3 −−
−−
−−
−−
# Points −− 46 −− 58 −− −−
# Labs 1 1
Fuji Dri−Chem Series • Fuji Dri−Chem IP−P, REF 9903170

Mean −− 2.20 −− 4.14 −− −−
SD
CV
1 −−
−−
0.035
1.6
2 −−
−−
0.133
3.2
3 −−
−−
−−
−−
# Points −− 17 −− 17 −− −−
# Labs 2 2

Mean −− 1.95 −− 3.91 −− 7.40
SD
CV
1 −−
−−
0.136
7.0
2 −−
−−
0.180
4.6
3 −−
−−
0.231
3.1
# Points −− 3877 −− 2890 −− 3954
# Labs 10 7 10

Mean −− −− −− 3.82 −− 7.02
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.075
2.0
3 −−
−−
0.115
1.6
# Points −− −− −− 100 −− 100
# Labs 1 1

Mean −− 1.91 −− −− −− 7.43
SD
CV
1 −−
−−
0.062
3.2
2 −−
−−
−−
−−
3 −−
−−
0.229
3.1
# Points −− 89 −− −− −− 91
# Labs 1 1

Mean −− 2.14 −− −− −− 7.86
SD
CV
1 −−
−−
0.101
4.7
2 −−
−−
−−
−−
3 −−
−−
0.287
3.7
# Points −− 14 −− −− −− 14
# Labs 1 1
Mindray BS Series
Mean −− 1.97 −− 3.90 −− 7.39
SD
CV
1 −−
−−
0.090
4.6
2 −−
−−
0.088
2.3
3 −−
−−
0.181
2.4
# Points −− 405 −− 422 −− 424
# Labs 3 2 2
Mindray CL Series
Mean −− −− −− 3.83 −− 7.25
SD
CV
1 −−
−−
−−
−−
2 −−
−−
0.060
1.6
3 −−
−−
0.114
1.6
# Points −− −− −− 269 −− 270
# Labs 2 2
RANDOX RX daytona
Mean 2.25 2.10 4.33 4.10 8.29 8.29
SD
CV
1 0.158
7.0
0.238
11.4
2 0.212
4.9
0.372
9.1
3 0.000
0.0
0.000
0.0
# Points 20 112 16 105 1 1
# Labs 1 1 1 1 1 1
RANDOX RX imola
Mean 1.96 1.92 3.93 3.84 −− −−
SD
CV
1 0.064
3.3
0.074
3.9
2 0.087
2.2
0.115
3.0
3 −−
−−
−−
−−
# Points 26 224 24 194 −− −−
# Labs 1 1 1 1

Mean 1.93 1.92 3.91 3.86 7.32 7.35
SD
CV
1 0.085
4.4
0.089
4.7
2 0.104
2.7
0.109
2.8
3 0.173
2.4
0.167
2.3
# Points 2635 86347 372 38511 2624 91225
# Labs 47 188 11 110 46 202

Mean −− 1.90 −− −− −− 7.20
SD
CV
1 −−
−−
0.000
0.0
2 −−
−−
−−
−−
3 −−
−−
0.000
0.0
# Points −− 1 −− −− −− 1
# Labs 1 1

Mean 1.95 1.93 3.88 3.87 7.39 7.41
SD
CV
1 0.040
2.0
0.054
2.8
2 0.080
2.1
0.076
2.0
3 0.122
1.7
0.150
2.0
# Points 310 10484 233 9084 165 9534
# Labs 8 26 5 18 6 24
Multiqual 1,2,3 • Lot 45910 • Exp 31−Mar−2024 Conventional

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January 2024

Acetaminophen Chemiluminescence µg/mL

Beckman Coulter AU Series

Siemens Dimension Series

Method Group • Chemiluminescence

Acetaminophen Colorimetric µg/mL

Siemens Dimension Series

VITROS Microslide Series • Slide generation #17

Method Group • Colorimetric

Copyright © 2017 Bio−Rad Laboratories, Inc. Generated 28−Feb−2024 22:18:49 Page 1

Acetaminophen EIA µg/mL

Beckman Coulter AU Series • Emit tox Acetaminophen REF OSR7A229

Roche cobas 6000/8000/c 311

Roche cobas c 303/503

Roche cobas c 303/503 • Roche ACET2, REF 08056684

Method Group • EIA

Acetaminophen Enzymatic µg/mL

Roche cobas 6000/8000/c 311

Siemens ADVIA Chemistry Systems

Copyright © 2017 Bio−Rad Laboratories, Inc. Generated 28−Feb−2024 22:18:49 Page 2

Acetaminophen Enzymatic µg/mL

VITROS Microslide Series • Slide generation #15

VITROS Microslide Series • Slide generation #17

Method Group • Enzymatic

Acetaminophen Enzymatic, colorimetric µg/mL

Abbott ARCHITECT/Alinity (c, i, ci models) • Sekisui Diagnostics SEKURE

Roche cobas 6000/8000/c 311 • Roche Acetaminophen, No Correction

Siemens Atellica CH Analyzer

Siemens Dimension Series

Siemens Dimension Vista

Copyright © 2017 Bio−Rad Laboratories, Inc. Generated 28−Feb−2024 22:18:49 Page 3

Acetaminophen Enzymatic, colorimetric µg/mL

VITROS Microslide Series • Slide generation #16

VITROS Microslide Series • Slide generation #17

Method Group • Enzymatic, colorimetric

Acetaminophen GC−MS µg/mL

Method Group • GC−MS

Acetaminophen Immunoturbidimetric µg/mL

Beckman Coulter UniCel DxC Series

Method Group • Immunoturbidimetric

Copyright © 2017 Bio−Rad Laboratories, Inc. Generated 28−Feb−2024 22:18:49 Page 4

Method Group • a−naphthyl phosphate, tartrate

Acid Phosphatase, Total a−naphthyl phosphate, end point U/L @ 37° C

Method Group • a−naphthyl phosphate, end point

Acid Phosphatase, Total a−naphthyl phosphate, kinetic U/L @ 37° C

Roche cobas 6000/8000/c 311

Spectronic Genesys • Biosystems S.A.

Method Group • a−naphthyl phosphate, kinetic

Albumin Agarose Gel %

Copyright © 2017 Bio−Rad Laboratories, Inc. Generated 28−Feb−2024 22:18:49 Page 5

Albumin Agarose Gel %

Albumin Bromcresol Green (BCG) %

Method Group • Bromcresol Green (BCG)

Albumin Bromcresol Green (BCG) g/dL @ 37° C

Method Group • Bromcresol Green (BCG)

Albumin Bromcresol Green (BCG) g/dL

Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH AlbBCG2, REF 04T34

Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott ARCH AlbBCP2, REF 04U45

Copyright © 2017 Bio−Rad Laboratories, Inc. Generated 28−Feb−2024 22:18:49 Page 6

Albumin Bromcresol Green (BCG) g/dL

Abbott ARCHITECT/Alinity (c, i, ci models) • Abbott Alinity c AlbBCP2, REF 04T82

Abbott ARCHITECT/Alinity (c, i, ci models) • Sekisui Clinimate