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  • Patient With Frontal Variant Syndrome in Early Onset Alzheim

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    Katia Schiano di Cola
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    (1) The document describes a patient who presented with early-onset Alzheimer's disease (AD) but exhibited symptoms similar to frontal-variant frontal temporal dementia (fvFTD), including problems with behavior and decision-making. (2) Brain amyloid imaging using PET scanning supported a diagnosis of AD rather than fvFTD. (3) This case highlights the clinical variability of early-onset AD and the importance of a multimodal assessment of rare forms of dementia.

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    (1) The document describes a patient who presented with early-onset Alzheimer's disease (AD) but exhibited symptoms similar to frontal-variant frontal temporal dementia (fvFTD), including problems with behavior and decision-making. (2) Brain amyloid imaging using PET scanning supported a diagnosis of AD rather than fvFTD. (3) This case highlights the clinical variability of early-onset AD and the importance of a multimodal assessment of rare forms of dementia.

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    3 views1 page

    Patient With Frontal Variant Syndrome in Early Onset Alzheim

    Uploaded by

    Katia Schiano di Cola
    (1) The document describes a patient who presented with early-onset Alzheimer's disease (AD) but exhibited symptoms similar to frontal-variant frontal temporal dementia (fvFTD), including problems with behavior and decision-making. (2) Brain amyloid imaging using PET scanning supported a diagnosis of AD rather than fvFTD. (3) This case highlights the clinical variability of early-onset AD and the importance of a multimodal assessment of rare forms of dementia.

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    Patient with frontal-variant syndrome in early-onset Alzheimer's disease.

    Author
    Cai H(1), Ning S(2), Li W(2), Li X(2), Xiao S(2), Sun L(2)

    Author Information
    (1) Department of Geriatric Psychiatry of the Fourth People's Hospital, Wuhu, Anhui,
    China.
    (2) Alzheimer's Disease and Related Disorders Center, Department of Geriatric Psychiatry, Shanghai
    Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

    Abstract: The clinical manifestation of frontal-variant Alzheimer's disease (fvAD) is not typical, and it is difficult yet
    necessary to differentiate fvAD from frontal-variant frontal temporal dementia (fvFTD). We describe a patient with
    þÿearly-onset Alzheimer's disease (AD) who presented with an fvFTD-like syndrome and apolipoprotein E [3/ [4
    genotype. A brain amyloid imaging procedure, 11C-Pittsburgh compound B positron emission tomography (PET),
    supported the final diagnosis of AD. Our present case highlights the clinical variability that characterises early-onset
    AD. A multimodal approach is crucial when assessing rare forms of dementia.

    © Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and
    permissions. Published by BMJ.

    Gen Psychiatr 2020 ;33:e100173. [epublish]

    Keywords:

    PMID: 32215362

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