SRI VENKATESHWARA DENTAL COLLEGE AND HOSPITAL THALAMBUR CHENNAI DEPARTMENT OF BIOCHEMISTRY BDS—I YEAR ESS. 1. Gluconeogenesis and its regulation. 2. Glycolysis , Energetics and its regulation. 3. TCA cycle and its regulation. 4, Regulation of Blood sugar and add a note on HbA \¢ 5. What is Diabetes mellitus? Discuss the classification and the clinical presentation of the disease. 6.GTT 7. How ammonia is formed? Describe the urea cycle in detail. Add a note on disorders associated with it 8. What are Aromatic amino acids? Explain the metabolism of any one of the Aromatic amino acids. 9. B- Oxidation of fatty acids and its Energetics . 10. What are ketone bodies. Explain the process of ketogenesis and ketolysis. Write any two conditions of increased production of ketone bodies. 11. Explain the biosynthesis of cholesterol. Bring out the significance of the specialized products obtained from cholesterol. 12. Discuss fatty acid synthesis and it’s regulation,13. Discuss the classification of Enzymes with suitable examples. Add a note on the factors influencing enzyme action. 14. Write an essay on “Calcium Homeostasis”. Give the normal plasma calcium level. 15. Write about the synthesis and utilization of ketone bodies. Name any two conditions of increased ketone bodies production and write about the evaluation ot ketone bodies. 16, Write the sources, RDA, chemistry, biochemical functions, deficiency manifestations of Vitamin A. 17. Write the sources, RDA, chemistry, biochemical functions, deficiency manifestations of Vitamin D. 18. Write the sources, RDA, chemistry, biochemical functions, deficiency manifestations of Vitamin C. 19. Write the sources, RDA, chemistry, biochemical functions, deficiency manifestations of Vitamin B6 20. Write the sources, RDA, chemistry, biochemical functions, deficiency manifestations of Vitamin B12 21. Write the sources, RDA, chemistry, biochemical functions, deficiency manifestations of Calcium 22. Write the sources, RDA, chemistry, biochemical functions, deficiency manifestations of Iron. 23. Define Enzymes and Iso enzymes with suitable example. Classify enzymes with examples. 24. Write the classification and factors influencing enzyme actionSHORT NOTES 1. Glycogen storage disease. 2. Significance of HMP shunt. 3. Glycogenolysis. 4. Renal glycosuria. 5. Galactosemia. 6. Substrate level Phosphorylation. 7. Cori’s cycle. 8. Complication of Diabetes mellitus. 9.Von Gierker’s Disease. 10. Lab investigation that should be carried out in a Diabetic patient to monitor Diabetes control. 11. Phenylketonuria. 12. Alkaptonuria. 13. Specialized product obtained from Tyrosine. 14. Disorders associated with Aromatic amino acids metabolism. 15, Gout. 16. Genetic code. 17. Gene mutation. 18, Antimetabolites. 19. Atherosclerosis. 20. Lipotropic factors. 21. Niemann -pick disease.22. 23. 24. 25. 26. 27. 28. 29. 30. 31 34. 35. 36. 37. 38. 39. 40. 41. 42. 43. 44. HDL Cholesterol. Biochemical functions, deficiency manifestations of Vitamin E. Biochemical functions, deficiency manifestations of Vitamin K. Beri beri. Pellagra. Biochemical functions of Thiamine. Co enzymes actions of vitamins. Folate Trap. Biochemical functions of Folic acid. . Scurvy. 32. 33. Biochemical functions of B2. Biochemical functions of Pantothenic acid. Biochemical functions of Niacin. Biochemical functions of Mg. Biochemical functions of Na. Biochemical functions of Potassium. Biochemical functions of Iodine. Biochemical functions of Phosphorous. Biochemical functions of Zinc. Wilson’s disease. Flurosis. Competitive Inhibition. Factors influencing enzyme activity.45. 46. 47. 48. 49. 50. Sl. 52. 53. S54. 55. 56. 37. 58. 59. 60. ol. 62. 63. 65. 66. 67. Significance of Km value. Clinical importance of any three enzymes. Mechanism of Enzyme action. Transaminases Mucopolysaccharides. Write a short note on Starch and Glycogen. Classification of Carbohydrates. Dietary fibers. Denaturation. Essential and Non essential amino acids. Structure of Immunoglobulin. Electrophoresis. Classification of Immunoglobulin. Chromatography. Plasma protein. Multiple Myeloma and its diagnosis. Structure of tRNA. Prostaglandins. Phospholipids. . Essential fatty acids. Types of Xenobiotics. Parkinson’s Disease. Rickets.68. Albinism. 69. Lesch Nyhan syndrome. 70, Hartnup Disease. 71. Orotic Aciduria. 72. Transmethylation. 73. Glycosylated Hb. 74. Hypercholesterolemia. 75. Lipoproteins. 76. Inhibitors of protein biosynthesis 77. Fatty liver. 78. LDL — Cholesterol. 79. Disorders of B - Oxidation pathway. 80. Jaundice. 81. Renal function test. 82. Tay sach’s disease. 83. Balanced diet. 84. Metabolic Acidosis. 85. LDH Isoenzymes and its clinical importance. 86. Hypervitaminosis. 87. Metabolic Alkalosis. 88. Fluorosis. 89. Limiting Amino acids. 90. Oxidative Phosphorylation.91. Respiratory Acidosis. 92. Wilson’s Disease. 93. Sickle cell Anemia. 94. Thalassemia. 95. Iron deficiency Anemia. 96. Toxicity of Iron. 97. Deficiency manifestations of Iodine. 98. Deficiency manifestations of Vitamin A. 99. Respiratory Alkalosis. 100. Disorders of Sodium metabolism. 101. Hypercalcemia and Hypocalcemia. 102. CPK & ALP. 103. Blood buffers. 104. LIVER FUNCTION TEST. 105. VANDENBERG REACTION. 106. Thyroid function test 107.