Gee 5)
1, Dug A produces constriction c 1pil — miosis
any change in-light reflex, co neal reflex,
without :
~ or status of conjunctival blood vessc|s.
‘A is acting on MB receptor siti to! ia
Af
Apa Le
Drug We
circular muscle of iris (constrictor pv
and produces constriction of pupillary size
known as miosis.
* Drug A could be"cholinomimetic drug like
b —- withoipigeurpine'Or physostigmine. |
warstitus: o Co oajunctiwall blo. k
2. This drug is used to treat glaucoma.
2 Dn i noon N13 er i
+ In open angle glaucoma — it increases the
»
of cili juscles which improves the
tone of iliary spuseles Mc mn tee
alignment of trabecular meshwork so that
KitOwn AS MILOSIS. :
4 the outflow is increased.
. nan He ,glosure, glaucoma - by contraction
of sphincter pupillae it makes the iris thin
_ Mnd“pulls"it“aWay"from the Iens removing
o pupillary . block;,and restoring aqueous
drainageanary muscies
ont eshineter pupiltae | s Tridel__ 1. Drug A produces dilation of pupil and abolishes ie
comeal reflex. |
* There is vasoconstriction of conjunctival
Iii blood vessels. There is no effect on light
\ oe
reflex.
«, * Dilatation of pupil is due to contraction of
radial muscles of iris and abolishing of corneal
rr \, Lreflex isiduetodocaltanesthetic action of drug.
2. Driig A’ is cocaine (local anesthetic with
sympathomimetic property.
* Being an LA, ‘it’ causes logs of nerve
conduction and loss of corneal reflex.
2 a the periphery it can block uptake of
drenaline and NA into adrenergic nerve
€nc 28’ thereby increasing their concentration
near receptors. (
yDrug Treatment
Parameters:
Cong.
Normal _|
Normal
Normal
alele
Normal
Normal
LR = Light Reflex
1. Explain the effects of Drug “A” 0:
2. What is cycloplegia?
3. With reason, list one clinical condi
C.R -Comeal Reflex C.V — Status of Conjunctival blood vessels,
is contraindicated?oa
intraocular pressure.
| |
es mydriasis and loss| of light reflex
al reflex ‘and status of
1, Drug A produc
with no change in come:
conjunctival vessels. 4
"Therefore it can ‘be an anticholinergic like*
Atropine, ‘Homatropine, Cyclopentolate, and
Tropicamide.
2, Cycloplegia is paralysis of ciliary muscle of the eye
1. Which Aeads to. doss,af 2 accomadation. Cycloplegic
mugs cause, Paralysis of of, f ciliary 1 muscles of the eye
because of which the “curvature of the lens can no
longer be adjusted to fos nearby objects.
° Therefore it can
+ These. a dugy alse abolish ‘light reflex and cause
-. mydriasis. .
cand Narrow iridocorneal angle. Both
( 5 al eyelet gat be menpng Ba
of _ glaucoma, , because . the. drug fends to rise
to-This ris