Cells
1 Stem cells from the patient are put in a
growth medium so they can multiply. When
sufficient cells are available they are put in to
bioprinter cartridges.
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2 The stem cells form what can be terrned
a ‘bioink’ which, once loaded into cartridges,
can be used in the bioprinting process.
A cartridge is made from a chamber
attached to a long extrusion nozzle fitted
with a syringe.
Bi Figure 11.22 Bioprinting
Lt
3 The bioprinter is driven by software that
lays down the stem cells in precise patterns.
Cells can be put down in layers interspersed
with a water-based material called hydrogel,
which forms a temporary mould around the
cells. Sticky polymers can also be used to
form a scaffold for cells (see Figure 11.23).
The scaffolding material is laid down by
separate nozzles on the bioprinter.
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4The printed 5 The printed tissue can
tissueisleftto be used in transplants or
grow. in medical research