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jtIntroduction
Statistics:
A field of study concerned with the
collection, organization and summarization
of data, and the drawing of inferences about
a body of data when only part of the data
are observed.
Biostatistics: An application of statistical
method to biological phenomena.
The science of assembling and
‘interpreting numerical data
|(Bland 2000)
The discipline concerned with the
‘treatment of numerical data
derived from groups of individuals
(Armitage et al.,2001)Uses of Biostatistics
> Hospital utility statistics
> Resource allocation
> Vaccination uptake 7-8/179
> eMagnitudes of a disease/condition
> eAssessing risk factors
> Disease frequency
>eMaking diagnosis and choosing an
appropriate treatment (implicit/probability).
16/2018 By Or HAMZE ALL ABDILLAHI
Statistics can be used to:
1. Draw conclusions
2. Make predictions about
what will happen in other
subjects1) At Hargeisa general hospital, 5% |
of the patients were “lsenosed
with DM last year
9-10/179
2. Kat chewers are 3 times mo, .
to have MI than non-chewers |
3. Antibiotics reduce the duration of
viral throat infections by 1-2 days
(2672008 By Dr. HAMZE ALI ABDILLAHT 7
Nedical research vs. Clinical Practice
—-.s so SSS—S—SSSSSSsSs
* Data are collected
from individual
subjects
* Interested in the
particular subjects
* Data are collected
from individual
subjects
* Aim is to be able to
make some general
statements about a
wider set of subjects
that have been
studiedGeneral steps in a research process
What does Biostatistics cover?
Planning
Design 11-12/179
Data collection
Data Processing
Data Presentation
Data Analysis
Interpretation
, Publication
COS OG oe wT
By Dr HAMZE ALI ABOILLAHI 9
6) 20
Population & Sample
* Population: is a complete set of items
or subjects which can be studied
= Target population: A collection of items
that have something in common for which
we wish to draw conclusions at a
particular time.
= Study Population: The specific population
from which data are collected.
= Sample: A subset of the study population.
(A smaller part of that population)
2 By.Dc HAMZE ALL ABDILLALL noGeneralizability:
is a two-stage procedure: we
want to generalize conclusions
from the sample to the study
population and then from the
study population to the target
population.
2/26/2018 By Dr HAMZE ALI ABOILLAHI n
example
In a study of the prevalence of Kat chewing
among secondary students in Somalia a
random sample of Secondary students in
Hargeisa were taken.
Target Population: All secondary students
in Somalia
Study population: All secondary students
in Somalilandexample
In a study of the prevalence of Kat chewing
among secondary students in Somalia a
random sample of Secondary students in
Hargeisa were taken.
Target Population: All secondary students
in Somalia
Study population: All secondary students
in Somaliland
Sample: secondary students in Hargeisa
2/26/2018 By Ox HAMZE ALI ABDILLAH! 2
Study
population
Target
populationParameter & Statistic
Parameter:
A descriptive measure computed from
the data of a population. (Quantity
calculated from population). E.g. mean serum
glucose of the population is 100mg/dl
Statistic:
A descriptive measure computed from
the data of a sample. (Quantity
calculated from the sample). E.g. mean
serum glucose of the sample is 110mg/dl
16-17/179
roars by
Scales of measurement (types of data)
¢ Clearly not all measurements are the
same.
e Measuring an individuals weight is
qualitatively different from measuring
their response to some treatment on a
three category of scale, “improved”,
“stable”, “not improved”.
e Measuring scales are different
according to the degree of precision
involved.
2/26/2018 fy Dr HAMZE ALI ABDILLAH!Types of scales of measurement.
There are four types of scales of measurement:-
A. QUALITATIVE DATA:
1. Nominal scale: (can not be ordered)
uses names, labels, or symbols to assign each
measurement to one of a limited number of
categories that cannot be ordered.
Examples:
Blood type (A/B/AB/O) sex (Male/female) race
(Somali/ Oromo) marital status (married/not
married/ divorced). If there are only two possible
categories the data is said to be Dichotomous ( e.g.
row 9K, Male/FEmalley, sau sos
16
2. Ordinal scale (categories can be
placed in order): assigns each measurement
to one of a limited number of categories that
are ranked in terms of a graded order.
Examples: |
*A questionnaire may ask respondents how.
happy they are with quality of services
provided at the hospital, the choices can
be: very happy, quite happy, unhappy, vey
mnhanny2. Ordinal scale (categories can be
placed in order): assigns each measurement
to one of a limited number of categories that
are ranked in terms of a graded order.
Examples;
*A questionnaire may ask respondents bow
happy they are with quality of services
provided at the hospital, the choices can
be: very happy, quite happy, unhappy, vey
unhappy.
2/26/2018,
*Degree of malnutrition
= mild, moderate, severe
*Socio-economic status x
‘>
= upper, middle, lower |
2726/2018, By Dr. HAMZE AU ABDILLAHL
18*Degree of malnutrition
= mild, moderate, severe
*Socio-economic status
= upper, middle, lower
Se
B. QUANTITATIVE DATA: (Numerical
data).
Continuous data:
* Interval scale
* — Ratio scale
* Discrete (numbers)
3. Interval scale (equally spaced intervals):
assigns each measurement to one of an
unlimited number of categories that are
equally spaced. It has no true zero point.
Example:
body temperature measured on Celsius
or Fahrenheit, heart rate measured per
second. Thus the difference of interval
between 5kg and 10kg is same as that
between 20kg and 25kg.
These kind of measurement can be
converted into dichotomous nominal
scale e.g. afebrile (oral temp < 37) febrile
(>37) also can be ordered (ordinal scale).4.Ratio scale: measurement
begins at a true zero point and the
scale has equal space. Ratio data is
similar to interval scales but it is
the ratio of two measurements
and also have a true zero.
Examples: Height per weight,
blood pressure.
5. Discrete data: (numbers)
All values are clearly separated from
each other, although numbers are
used.
Examples: number of — surgery
Operations performed in one month.
Number of newly diagnosed
psychiatric patients last year.
2/26/2018 ByOc HarVariables
¢Variable: A characteristic which takes different
values in different persons, places, or things.
*Qualitative variable: The notion of magnitude is
absent or implicit.
eQuantitative variable: Variable that has
magnitude.
*Discrete variable: It can only have a finite
number of values in any given interval.
*Continuous variable: It can have an infinite
number of possible values in any given interval.
2n6fo1e 6 Dr: HAMZE ALI ABDILLAHI 23
Data
The term DATA refers to (Items of
information)
Systems for collecting data
1.Regular system (routine data collecting
system): Registration of events as they
become available.
2.Ad hoc system (non-routine): A form of
survey to collect information that is not
available on a regular basis.1.
5.
Examples;
Routine system:
Census: enumeration of all individuals in a country on
a fixed day.
Vital registrations: birth, deaths, marriage, divorce,
ete.
Disease notification: international notification, like
cholera, national notification like polio, cholera,
hepatitis = notification is from district level to national
level to international level.
Disease registry: TB, cancer, stroke, birth defects
Medical records: schools, colleges, industries
Hospital records
Environmental health records
2/26/2018 By Dr. HAMZE ALI ABDILLAH 25
2. Non-routine
Disease surveillance: Polio, malaria, AIDS= it is
important for control, prevention and
eradication.
Surveys: nutritional status by interviewing
examination or postal enquiry based.
Social schemes: medical insurance, sickness
absenteeism, disability benefits, welfare schemes
Economic data: Consumption of goods, export
and import, drugs, employment = helps panning
commission for formulation of health policies
Demographic data: population movement, majorsource of data
1.Primary data: collected from the
items or individual respondents directly
for the purpose of certain study.
2.Secondary data: which had been
collected by certain people or agency,
and statistically treated and the
information contained in it is used for
other purpose.
2/26/2018 By Dr. HAMZE ALI ABDILLAHI 27Cc
OTATISTICS “Derinition
Statistics us 0 baumch that deals with every aspect
te date Statts tal Krowlidye Aulps to choose
the poropex metho o Callecting he dda, anck
employ Yhese amples um dhe Laxnect is
Puocers 5 tn Oxdex oo efeciely btoduce the
wus. In Shot, Statistios ts a oucrot
Puocess y which helps to make he dhision
based On the chta-
Some other definitions we %—
According to King -" The ‘Acvence q Sebypits os
the Method jedgiong tallechive
‘ natural a focal phenomencn pom whe
wteaulls oblatned fam the Analysis 0X Cmumeration
yl Collection af eattmases .”
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. Which deals wth
tre Collection y amelie and dtesuelaton of
umva'cal dada.q
Matistics ane
Cunracrenicnes Or Stonaticg
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cue rmummoricably Exporene ol
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Slalisios ane toblated un Ssedebornined Manner.
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24-25/37I
oO
St poeavides the eat description anol beter
Tmerortawce Ur Sratstics
“The Jmnposdantt hurmtions of Stedinticn abe.
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bhuchuiate quamditasive data:
HM depcale the Complex data iw the graphical foum,
tabular form and Un daaranel wopuestrdedior7 9
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dheis onnnual siebosit » Rod accounts dnd bomk.
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Sfrontsh Sadistic deals uth stelsntyues tl fo
the analysis f dita. y making Chiimases avd wig
latees fom Sinind Sfornaon bs
oo ————_ 97/37 *DIE TIIIS=’S!S'=s~ a ED
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