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INDIUM-111 RADIOPHARMACEUTICALS GROUP

CHEMICAL CHEMICAL NAME HALF LIFE IMAGING DIAGNOSTIC USE


SYMBOL
Indium-111 CapromabPendetide Diagnostic imaging agent: Proven prostate cancer(to be clinically localized after standard diagnostic evaluation),
high-risk for pelvic lymph node metastases, post-prostatectomy (w/ rising PSA, equivocal standard metastatic
111In 2.80 days SPECT evaluation, high clinical suspicion of occult metastatic disease)
Indium-111Chloride Labelling monoclonal antibodies and peptides
Indium111 Radionuclide cisternography: Cerebrospinal fluid imaging
Diethylenetriaminepentaacetic
Acid (DTPA)
Indium-111 Oxyquinoline Radiolabelling autologous leukocytes (used as an adjunct in the detection of inflammatory processes to which
leukocytes migrate) e.g. associated abscesses or other infection
Indium-111Pentetreotide PLANAR (Agent) Scintigraphic localization: Primary and metastatic neuroendocrine tumors bearing somatostatin receptors.
Imaging: neuroendocrine tumors
Indium111 Imaging: metastatic disease associated w/ colorectal & ovarian cancer
SatumomabPendetide
Indium 111 labelled white blood PLANAR Sites of infection (Detection of inflammation)
cells

CARBON RADIOPHARMACEUTICAL GROUP


CHEMICAL CHEMICAL NAME HALF LIFE IMAGING DIAGNOSTIC USE
SYMBOL
11 C Carbon-11 Choline 20.334 minutes PET Suspected prostate cancer recurrence based upon elevated blood prostate specific antigen (PSA)
14 C Carbon-14 urea 5,730 years Detection of gastric urease as an aid in the diagnosis of H.pylori infection in stomach

YTTRIUM-90 RADIOPHARMACEUTICAL GROUP


CHEMICAL CHEMICAL NAME HALF LIFE IMAGING DIAGNOSTIC USE
SYMBOL
90Y Yttrium-90 Chloride 64 hrs Radiolabelling: used for radioimmunotherapy procedures
Yttrium-90 Treatment: relapsed low-grade or follicular B-cell non-Hodgkin’s lymphoma
Ibritumomabtiuxetan untreated follicular NHL who achieve a partial or complete response to first-line chemotherapy
FLUORINE-18 RADIOPHARMACEURICAL GROUP
CHEMICAL CHEMICAL NAME HALF LIFE IMAGING DIAGNOSTIC USE
SYMBOL
18F Fluorine-18 florbetapir 109.771 PET Suspected prostate cancer recurrence based upon elevated blood prostate specific antigen (PSA)
Fluorine-18sodium fluoride minutes Bone imaging agent to delineate areas of altered osteogenesis
Fluorine-18 Assess abnormal glucose metabolism in oncology &myocardial hibernation.
fludeoxyglucose Identify regions of abnormal glucose metabolism associated w/ foci(epileptic seizures)

UNGROUPED RADIOPHARMACEUTICALS
CHEMICAL NAME HALF LIFE IMAGING DIAGNOSTIC USE
Gallium-67 3.26 days PLANAR Demonstrate the presence/extent of:
GalliumCitrate Hodgkin’s disease
Lymphoma
Bronchogenic carcinoma
Aid in detecting some acute inflammatory lesions
Mo-99 generator 2.7489 days Mo/Tc Generation of Tc-99m sodium pertechnetate for administration or radiopharmaceutical preparation.
generators
Nitrogen-13 Ammonia 9.97 min PET Imaging:
Myocardium
Pharmacologic stress conditions to evaluate myocardial perfusion
Suspected/existing coronary artery disease
Radium-223 dichloride 11.4 days Treatment:
Castration-resistant prostate cancer
Symptomatic bone metastases
Unknown visceral metastatic disease
Rubidium-82chloride 1.27 minutes PET Myocardial perfusion agent
Distinguishing normal from abnormal myocardium
Suspected myocardial infarction
Samarium-153EDTMP 46.3 hours Pain reliever for confirmed osteoblastic metastatic bone lesions
Strontium-89 chloride 50 days Bone pain reliever for skeletal metastases that have been confirmed prior to therapy
Thallium-201 chloride 72.912 hrs SPECT/PLANAR Imaging: Myocardial perfusion
Localization: myocardial infarction
Supplemental diagnosis: ischemic heart disease (atherosclerotic coronary artery disease)
Localization of sites: parathyroid hyperactivity w/elevated serum calcium and parathyroid hormone levels.
Xenon-133gas 5.2475 days PLANAR Evaluation of pulmonary function, imaging for lungs & Assessment of cerebral flow
IODINE RADIOPHARMACEUTICALS GROUP
CHEMICAL CHEMICAL NAME HALF LIFE IMAGING DIAGNOSTIC USE
SYMBOL
Iodine-123 Lobenguane 13.22 SPECT Detection of primary/metastatic pheochromocytoma or neuroblastoma
123I hours Imaging: Neuroendocrine tumor
Iodine – 123 Ioflupane Brain Imaging: Striatal dopamine transporter visualization
Evaluation of Suspected Parkinsonian Syndrome: differentiate essential tremor e.g. (idiopathic Parkinson’s disease,
multiple system atrophy and progressive supranuclear palsy)
Iodine– 123 Sodium iodide Evaluation of thyroid, Function and Morphology
125I Iodine– 125 Human serum 59.4 days Determining Total blood Plasma volume
albumin
Iodine– 125 Iothalamate Evaluation of glomerular filtration
Iodine – 131Human serum Used in determining:
131I albumin 8.0197 Total blood and plasma volumes
days Cardiac output
Cardiac and pulmonary blood volume and circulation time
Protein turnover studies
Heart and great vessel delineation
Localization of the placenta
Localization of cerebral neoplasm
Iodine – 131 Sodium iodide SPECT Radioactive iodide(RAI) test: Evaluate thyroid function
Localizing metastases associated with thyroid malignancies
Treatment for :
Hyperthyroidism
Carcinoma of the thyroid
Iodine – 131 Tositumomab Treatment for:
CD20antigen-expressing relapsed or refractory,
Low grade ,follicular, or transformed non-Hodgkin’s lymphoma
Rituximab-refractory non-Hodgkin’s lymphoma
Iodine– 131Iodohippurate To determine renal function, effective renal plasma flow, urinary tract obstruction
sodium
TECHNETIUM-99M RADIOPHARMACEUTICALS GROUP
CHEMICAL CHEMICAL NAME HALF IMAGING DIAGNOSTIC USE
SYMBOL LIFE
Technetium-99m bicisate SPECT Localization of Stroke
Technetium-99m disofenin Diagnosis of Acute Cholecystitis
Technetium-99m exametazine Detection of altered regional perfusion in stroke
Leukocyte labelled scintigraphy for inflammatory bowel disease
Technetium-99m macroaggregated albumin PLANAR Evaluation of pulmonary perfusion & peritovenous shunt patency(artery)
Technetium-99m mebrofenin Imaging agent for hepatobiliary
Technetium-99m medronate PLANAR Bone imaging agent for delineation of altered osteogenesis
Technetium-99m oxidronate
99m
Tc Technetium-99m mertiatide 6.0058 Imaging agent for:
Hrs Renal Failure
Urinary Obsturction
Calculi
Renal Function

Technetium-99m pentetate Bone imaging


Kidney imaging (asses renal function, estimate glomerular filtration rate)
Technetium-99m pyrophosphate Bone imaging agent: Altered osteogenesis
Cardiac imaging agent: diagnosis of acute myocardial infarction
Blood pool imaging agent: usefule for gated blood pool imaging, detection of the site for GI Bleeding
Technetium-99m red blood cells Blood pool imaging: Cardiac 1st pass & gated equilibrium imaging
Detection of the site for GI Bleeding
Technetium-99m sestamibi SPECT/ PLANAR Imaging agent for myocardial perfusion
Planar breat imaging: 2nd line diagnostic drug (mammography) & for evaluation of breast lesions
(palpable mass)
Technetium-99m sodium pertechnetate Imaging for:
Bone
Thyroid
Salivary Gland
Placenta localization
Urinary imaging: detection of vesico-uretral reflux
Nasolacrimal drainage system imaging
Technetium-99m succimer Scintigraphic evaluation of renal parenchymal disorder
Technetium-99m methylene diphosponate PLANAR Initial method to detect skeletal Metastatic spread of cancer (Bone metabolism)
(MDP)
Technetium-99m sulfur colloid Imaging of functioning retriculoendothelial cells in liver, spleen & bone marrow
Technetium-99m tetrofosmin SPECT/PLANAR Myocardial perfusion agent: detecting coronary heart disease
Technetium-99m tilmanocept Lymphatic mapping w/ handheld gamma camera counter
Localization of lymph node draining primary tumor site w/ breast cancer or melanoma
Technetium-99m diethylene triaminepenta SPECT For renal function (Kidney Disease)
acetic acid (DTPA)
Technetium-99m mercapto-acetyl-triglycine PLANAR
Technetium-99m SPECT/ PET Brain scan for Alzeihmer’s Disease using PET Scan
hexamethylpropyleneamineoxime (HMPAO) Cerebral blood flow (Neurologic Disorders)

Technetium-99m For gall bladder imaging aka (cholescintigraphy)


hydroxy-iminodiacetic acid (HIDA)
paraisopropyl iminodiacetic acid (PIPIDA)
diisopropylacetanilidoiminodiacetic acid
(DISIDA)
Technitium- 99m Ethyl cysteine dimer SPECT Cerebral blood flow (Neurologic Disorders)

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