Professional Documents
Culture Documents
Harnessing
the Power of
Data in Health
June 2017
Foreword from
Stanford Medicine
Dean Minor
Today across the world, enormous to better understand the most important
transformations are taking place in health care trends and gain insight into the
health care. future. We interviewed industry experts
to better understand those trends and
Demographic, economic and technolog- how they envision the future of medicine.
ical changes are forcing us to reconsider And we spoke to our own faculty to better
everything about health care, from its understand their work and how it fits into
delivery to its funding models, from the wider picture. patient’s various personalized
education to scientific innovation and monitoring devices, whether they be
from the role of the physician to the What has become very clear from wearables or home devices, can now
role of pharmaceutical companies, the findings in this paper is that be interpreted to identify trends and
payors and patients. the greatest force behind these markers of future disease.
trends is data.
Like the rest of the world, health care is But that is just the start. Among many
becoming increasingly connected but Whether it is health wearables or things, data will change how doctors,
also increasingly complex. This poses on-demand testing, better hospital health care teams and institutions like
both an opportunity and a challenge to software or algorithms capable of catching Stanford partner together, how cost is
institutions like our own whose job it is to disease more effectively, rapid change is rationalized to increase accessibility
heal, innovate and educate. taking place because of increased access and, most importantly, how we protect
to big data and advanced data analytics. patient privacy and maintain patient
That’s why, given all of these forces If this continues – and we firmly believe it trust. We do not expect to provide all
shaping health care, I am very pleased to will – doctors will need to learn new skill the answers here. But we do hope it’s
introduce Stanford Medicine’s inaugural sets that, in turn, will require changes to the start of a lively debate and, if you
Health Trends Report. education and learning. As Kleiner Perkins’ have any feedback or thoughts, I’d be
Mary Meeker stated in her recent Internet delighted to hear them.
Our aim in producing this Report is to draw Trends Report, “health care is at a digital
together the key trends facing the health inflection point.” We couldn’t agree more. I hope you find the inaugural
care sector and by doing so inform and But what role will big data play? Health Trends Report valuable.
educate patients, doctors, governments
and other members of the medical We at Stanford Medicine believe in a vision
community about the opportunities and of health care – Precision Health – that is
challenges that lie ahead. If there is one more preventive, predictive, personalized
thing we can confidently predict about and precise. By leveraging big data and Lloyd B. Minor, MD
the future, it’s that the trends we have scientific advancements while maintaining Dean
identified in this paper will upend our the important doctor-patient bond, we Stanford University School of Medicine
thinking and revolutionize patient care. believe we can create a health system
that will go beyond curing disease after
To produce the Report, we undertook a the fact to preventing disease before it
comprehensive review and analysis of a strikes by focusing on health and wellness.
wide range of existing open-source data For instance, the data gathered from a
Executive
Stanford Medicine
Summary
The future of health care is being Data is permeating every component of When it comes to the road ahead, it will
shaped dramatically by a number of the health care ecosystem: be absolutely vital that all players in the
significant trends. • Medical research: Access to new, di- health care community, in both private
verse data and open datasets are fueling and public sectors, come together to
With the cost of care on the rise, the drug discovery and making clinical trials overcome several challenges:
industry is experiencing a shift toward and research more efficient. • Rising costs: Spiraling costs across the
preventive and value-based care. At the • Daily life: Wearable devices, online U.S. health care system could nullify the
same time, technology like wearable diagnostic tools and genetic sequencing additive role data plays.
devices, at-home testing services and services hold the promise of better • Data sharing and security: Silos and
telemedicine are empowering patients informed and engaged patients. roadblocks prevent effective data shar-
to be more engaged with and proactive • The patient experience: Health ing but, at the same time, privacy and
about their own health. Meanwhile, the systems are investing heavily in security of patient data is paramount.
industry is grappling with the tension technology, including machine learning, • Policy and legislation: Data privacy
between encouraging data sharing which is proving as effective as or more and interoperability must be addressed
to maximize the benefits of data and effective than human diagnosticians. at a legislative level to create a
maintaining patient privacy and trust. • Ongoing care: Telemedicine and health regulatory environment that encourages
All of these developments are altering apps make it possible for physicians innovation and research while putting
the role of physicians and their relation- to see patients virtually, outside of patients first.
ships with patients. traditional facilities for increased access • Electronic medical records (EMRs):
and tailored care. Frustrations with the design of elec-
Behind these trends is one fundamental • Prediction and prevention: Health tronic medical records undermine the
force driving health care transformation: data is allowing doctors to build better physician-patient relationship.
the power of data. patient profiles and predictive models • Skills and training: Without proper
to more effectively anticipate, diagnose infrastructure and a data-literate clinical
and treat disease. workforce, health data can only be
collected and stored, not leveraged fully.
• Encouraging preventive health care:
Reliance on reactive health care will
hamper physicians’ ability to anticipate,
diagnose and treat disease.
Contents
Introduction 1
Medical Research 3
Daily Life 5
Ongoing Care 9
Rising Costs 12
Appendix 18
Introduction
Stanford Medicine
On the front lines of this change, quality of care and cost of care. At both
A number of important trends are
human capital needs are shifting as the individual and population level,
shaping the future of health care. As
technological advancements and data is helping us reach new frontiers
the cost of health care continues to
artificial intelligence transform how in how to treat patients, improve
climb, in the U.S. alone health care
care is delivered. Cybersecurity is top outcomes and achieve new solutions.
spending has outstripped inflation by
a 5:1 ratio over the past 10 years.1 As a of mind in an era of sophisticated
targeted cyberattacks, while industry In the Report that follows, we’ll share
result, we are seeing a shift toward
experts are pushing for more open the key trends in health care and the
encouraging preventive care through
data sharing infrastructure to gain way in which data is revolutionizing the
an increased focus on nutrition,
faster, broader insights into public industry and our view on how to best
exercise and wellness, and a pivot
health. Meanwhile, the rapid increase foster and embrace this change.
toward value-based payment models.
in corporate partnerships and VC
Along with the widespread use of funding in the sector are accelerating
online resources such as WebMD change at a powerful pace.
that sees 212 million unique monthly
visitors,2 the increased use of wearable Behind these key themes lies an
devices and at-home genetic testing important common thread: the
services are leading to a generation of power of data and its potential to
empowered patients who are taking fundamentally transform the future
increasing ownership of their health of health care.
far beyond the walls of their doctor’s
office. And on the horizon, the use of Information is becoming easier to
telemedicine is widely expanding collect, analyze and understand,
access to, and convenience of care opening the door for major advances
across the globe. when it comes to preventive care,
1
Data’s Impact on
Stanford Medicine
Health Care
2
Data’s Impact on
Stanford Medicine
Health Care
Long before patients enter their The popularity of wearable devices, such $350M
doctors’ offices, data is connecting as pedometers and heart rate monitors,
their day-to-day lives and behaviors is exploding. Experts predict that health
to tangible health outcomes. In three and fitness technology will see record U.S.
primary areas, the health care sector sales in 2017, with 35 million units in sales.9
is already making noticeable strides Global sales were estimated to be as high
outside of the doctor’s office: as 274 million devices in 2016.10 Among
• Wearable devices continuously collect consumers, fitness bands are the most
patient health care data popular type of wearable, and people cite
$15M
• Direct-to-consumer testing, including health as a top motivator for using the new
genetic tests wearable technologies.11
2010 2020
• Access to online research and medical
informational websites Source: Kalorama Information
Expected
Parents Impact ofincrease
believe an Wearable Technology
in wearable technology can improve their:
This market growth reflects a desire for
Health 85% on-demand care at more affordable prices.
As with wearables, the increased demand
Tech Proficiency 80%
for at-home testing demonstrates that
Parenting 77% patients are deliberately choosing to be
Productivity 77% more actively engaged and empowered by
Efficiency 70% taking greater ownership of their health.
Relationships 64%
The internet continues to empower
Stress Level 61%
patients by providing easy access to health
Source: PwC, “The Wearable Life 2.0”
information. Traffic patterns on sites like
MayoClinic.com and WebMD.com show
that patients are curious and eager to
The desire to understand individual health better understand and take control of
Top reasons to have
and take control of it is already prevalent. their health. According to the Department
a wearable device
As consumers continue to experiment with of Health and Human Services, as of 2003
new technologies, they will be more likely “over a third of U.S. adults would [have]
to adopt innovative iterations of wearables difficulty with common health tasks, such
83% that link the data produced directly to as following directions on a prescription
medical professionals, including doctors drug label or adhering to a childhood
and researchers. immunization schedule.”13 However,
Thermoelectric pulses to heat, cool, and consumers are now seeking to change
soothe your body via a bracelet that senses Various types of testing, including digitized that. According to analytics company
temperature, pain, and stress
glucose tests, blood pressure and genetic Quantcast, WebMD sees over 25 million
testing, are allowing individuals to take daily visitors, and the site is among the
control of their health without requiring 50 most-visited sites in the country. While
interaction with doctors, insurance health literacy remains an important issue
82%
companies or pharmacies. According to address, experts agree: in today’s world,
to a report from Kalorama Information, individuals begin their personal health
the direct-to-consumer testing market is journeys through at-home online research
The ability to track your child’s health,
safety, or location via wearables
expected to grow from $15 million in 2010 rather than a visit to the doctor’s office.
to $350 million by 2020.12
The Future A majority of people would be While the market is currently dominated
excited to experience wearable by recreational technology and fitness
As current trends continue, health care technology from the following: companies, there’s a market opportunity
data will eventually permeate many for health care organizations to enter the
aspects of a person’s life, where activities wearable market by delivering FDA-com-
and behaviors are constantly tracked and pliant, HIPAA-compliant devices producing
linked back to the medical community. medically robust and relevant data.
Some experts suggest that invisible or While experts are optimistic about a
65%
implanted wearables will become the future of empowered patients, it will be
norm and will create continuous streams incumbent on patients to prioritize their
of data and health tracking, while at-home own health literacy. As consumers are
testing will help detect diseases in a more doctors given access to more health data, it will
targeted way. For instance, research become part of the physician’s role to
from Stanford Medicine has shown that help interpret the troves of information
wearable devices can use biosensors to at their fingertips.
detect symptoms of possible illness, such
as Lyme disease.14 In a future of wearables
and testing, patients will no longer need
to feel physical illness to prompt them to
seek medical attention. The promise of
wearables is in the ability to detect and
62%
therefore treat illness at an earlier stage.
62%
health insurance
companies
6
Stanford Medicine
7
Stanford Medicine
Case Study: IBM Watson New Health Care Roles: Not only will National governments are also increasing
doctors require stronger data analysis their investments in personalized
IBM is developing an interface that would skills, but the physician’s office will need medicine, with France recently committing
allow Watson to analyze existing medical to add new roles to its roster. As machine €670 million to personalized medicine and
research on any given topic, then synthe- learning becomes a growing component genomics research.24
size and summarize the information for of health care, specialists in data science,
the doctor. The intention is to help doctors governance and IT infrastructure will
quickly determine the best treatment become vital to the practice or health
options for an individual based on the vast system. Industry analysts predict that 30
amounts of data available. percent of providers will use cognitive
analytics to interpret patient data by
The reason for which
The New Doctor: As data continues to 2018,22 which will require specialists to personalized medicine
define the health care space, physicians help implement these new technologies. is possible is because
will be required to understand technology you have access to that
to properly take advantage of new tools Personalized Medicine: In the near massive data that is being
at their disposal to make data analysis future, the doctor may also choose to use analyzed; and as you
more useful. Many predict educational personalized medicine as a treatment
programs will be designed to better train option by tailoring medication regimens
analyze it, you therefore
doctors in quantitative skills, statistics and to a person’s unique genetic makeup. This understand what is likely
data analysis. This is already taking place is done by integrating a person’s genetic to be the medical profile
with increased interest among medical blueprint with data on their lifestyle and of a certain individual
students studying the field of public environment, and evaluating it alongside and are able to dig much
health, who are focused on connecting an array of patient blueprints to predict deeper into what are his
health policy with data. illness and determine the best course
of treatment. Some analysts estimate
risks and what are his
Stanford Medicine has responded to this the current of size of the personalized ideal treatments if he’s
need to better understand datasets by medicine market to be at $1 billion, with already suffering.
investing in its Biomedical Data Science expectations that it will reach more than - Industry Expert
Initiative,21 which provides formal support $2 billion by 2022.23
to the study of complex datasets.
8
Stanford Medicine
9
Stanford Medicine
USA 4.1
Source: Statistia
10
Stanford Medicine
Prediction and Case Study: Chan-Zuckerberg more data on healthy people (rather than
Prevention Initiative exclusively on the sick) allowing for earlier
detection of disease.
In September 2016, Mark Zuckerberg and
How can we better harness data to Priscilla Chan announced their decision Emerging technologies make it possible to
predict and prevent disease before it to donate $600 million to form a new, routinely evaluate risks for each individual
strikes? Experts agree that health care as independent research organization: the patient based on their genomics. Currently,
we know it is primarily reactive in nature Chan Zuckerberg Biohub. This ambitious this is reserved for select cases, but as
– people tend to seek care, get tests and collaboration between Stanford, UC San genetic testing technology becomes more
monitor their health only in response Francisco and UC Berkeley aims to engage common and affordable, experts predict
to a problem. However, the medical in research projects with the goal of testing will become routine for all patients.
community is trying to shift from reactive developing and applying the technologies In addition, innovative wearable technol-
care to proactive and preventive care. that will enable doctors to prevent, cure or ogies currently in development will ensure
manage all diseases during our children’s that detection will take place beyond
lifetime. formal testing. While most “smart clothing”
Today today is fitness oriented, innovators in
Case Study: Stanford Byers Center the sector are working on applying the
An effort to prioritize prevention is on for Biodesign technology to early detection of diseases.
the rise, with universities, startups and For example, the “smart bra” by Cyrcadia
non-profits participating in the effort. The Stanford Byers Center for Biodesign is Health uses photoacoustic imaging to
At-home genetic testing companies developing a number of predictive devices detect early breast cancer.
such as Color Genomics and 23andMe to prevent disease before it strikes. These
are contributing to this effort with their innovations include a monitoring device
genetic testing kits that allow individuals that predicts pediatric asthma attacks
to better understand their genetic days before they occur, a cost-effective
predispositions. Non-profits such as the test for the genetic causes of heart disease
Foundation for Health in Aging and the and a rapid non-invasive test for potential Giving people the tools
Preventive Medicine Research Institute heart-transplant rejection. to enable them to make
are increasingly focused on educating and
changes in their screening
preventing disease, rather than simply Since 2011, nearly $2 billion has been
combatting them after they have already invested to fund health care companies
and health care and
hit. Companies like IBM, Google, Medtronic that use predictive analytics in health prevention approach is
and Merck are developing predictive care,31 and we expect to see this trend one of the highest return
devices to be integrated into daily life. continue in the coming years. impacts you can have in
This thriving ecosystem is contributing public health today.
to a future that is more preventive,
predictive and personalized. The Future - Industry Expert
11
The Road
Stanford Medicine
Ahead
The opportunities presented by data The U.S. faces health care costs that the number of hospital readmissions,
in health care are immense, but so continue to increase year over year, for instance. Data must be leveraged to
are the obstacles the sector faces as it outpacing inflation.33 Experts fear that identify areas that can lead to significant
evolves. To move forward, the following increasing costs will continue to crowd out cost reductions, and experts must trans-
challenges must be addressed: budgets at all levels, from state and federal late that data into actionable solutions
governments to the private sector. that yield healthier outcomes and lower
• Rising costs overall health care costs. Moreover, if we
continue to promote an open, collabo-
• Data sharing and security rative data environment, the financial
burden associated with medical research
• Policy and legislation and development can lessen significantly
The premiums for resulting in industry-wide savings.
• Electronic medical records (EMRs) employer-based
insurance are going
• Skills and training
up. The copays and Data Sharing and
• Encouraging preventive health care deductibles have gone Security
up faster than salaries.
The private and public sectors must You are finding families How can data sharing be encouraged
work closely together to overcome these struggling, businesses across the health care sector to facili-
challenges, listening to and engaging struggling, state, local tate medical research and pharmaceu-
with a range of voices across stakeholder tical research and development? At the
groups to ensure the solutions consider
and federal governments same time, how can we improve data
all individuals and communities who struggling. If health care security and protect patient privacy?
will be affected. costs continue unabated,
they will bankrupt A tension lies at the heart of the new age
potentially families and of health care. On one hand experts agree
Rising Costs some governmental that infrastructure and policies encour-
aging the sharing of data are essential
How can payors, medical systems, and
institutions, or crowd to maximize the benefits of big data. On
the technology sector combat the rising out many other kinds the other hand, the health care sector
cost of health care? of spending. has become a target for cybersecurity
- Stanford Faculty attacks and concerns exist when it comes
Experts recognize the cost of health care to protecting patient privacy. The industry
in the U.S. is a unique challenge. Among must resolve how to harness the full
industrialized nations, the U.S. spends a Managing health care costs will require potential of big data by sharing it to benefit
disproportionately high amount of money collaboration from all sector stakeholders. public health, while still ensuring patient
on health care – in fact, more than twice While government may be able to subsi- information remains safe and secure.
the OECD average. 32 dize drug prices, it cannot directly impact
12
Stanford Medicine
14%
1%1% Hacking/IT
information from a
5% 75%
75% special monitor that’s been
swallowed to track internal
4%
organ health Theft
14%
Loss
5%
70% health information collected
from a “smart toilet”
Unauthorized
Access/Disclosure
4%
Unknown
1%
47% health records Other
1%
13
Stanford Medicine
The threat to privacy and data security However, there is a consensus that policy fact, EMRs were at the top of a recent list
has grown more pronounced since the interventions are necessary to confront of ideas to transform health care in a STAT
“WannaCry” malware attacks in May 2017, many of the health care challenges we face news survey of 425 practicing physicians
which targeted the British National Health today and to realize the promise of data and health care leaders.36
Service and medical device companies in and new technologies.
the United States.
Policy often does not move fast enough Best Ways to Transform
Experts agree that striking a balance to keep up with innovation. Legislative Health Care
between effectively sharing and protecting bodies will need to address data privacy,
medical data will be challenging – but that interoperability and collaboration to
achieving this is critical to maximizing the create a regulatory environment that 1. Improving electronic health records
and related technologies to enhance
future of care. Finding the optimal solutions encourages innovation and research, while the experience of patients and
will require private and public sectors, protecting patients and accounting for their clinicians
payors and patients to collaborate. other stakeholders’ best interests.
14
Stanford Medicine
The job market has recognized the Infrastructure and Tools Organizations that lack the tools to
need to attract data-savvy talent. analyze data will only be able to collect
According to Glassdoor,38 the “Best Job” In addition to staff, experts believe that and store it, but they will not be equipped
for 2017 is “Data Scientist,” with “Data health care organizations will need to interpret the data to improve patient
Engineer” and “Analytics Manager” also to invest in the appropriate tools and outcomes or influence public health.
among the site’s top five. infrastructure to effectively manage data.
1st Data
Scientist
Data doesn’t do you any
good until you can turn it
into information, and that
a toy that will convert
everything you do all day
into one or another bit
is really our challenge. of data, and it’s easy to
2 nd DevOps
Engineer
- Stanford Faculty download that data into
little apps that you can
look at … But has any of
it been subject to the kind
3
The health care sector lags when it comes
rd Data to infrastructure and analysis. Research
of analysis that would
change your behavior?
Engineer from Deloitte identifies several ways that
the health care sector has failed to adopt Not yet.
effective data management strategies:40 - Stanford Faculty
4th Tax
Manager
5th
Management Strategies
Analytics
Manager
16
Stanford Medicine
17
Appendix
Stanford Medicine
1
“Medical Cost Trend: Behind the Numbers 15
“The Wearable Life 2.0: Connected living in a 30
“Americans Visit Their Doctor 4 Times A Year.
2017,” PwC, 2016. wearable world,” PWC Consumer Intelligence People in Japan Visit 13 Times A Year,” Forbes,
Series, 2016. September 2014.
“Inflation, consumer prices for the
United States,” Federal Reserve Bank of 16
“Adoption of Electronic Health Record 31
“The Future of Personalized Health Care:
St. Louis, 2017.
Systems among U.S. Non-Federal Acute Predictive Analytics,” Rock Health, October
Care Hospitals: 2008-2015,” ONC/American 2014.
2
“WebMD focuses on content, social media as
Hospital Association Annual Survey Informa-
users flock to mobile,” MobiHealth News,
tion Technology Supplement, May 2016. 32
“Health Costs: How the U.S. Compares With
August 2015.
Other Countries,” PBS, 2012.
17
“Allocation of Physician Time in Ambulatory
3
“Visualization Takes Open Data to the Next
Practice: A Time and Motion Study in 4 33
“Medical Cost Trend, Behind the Numbers
Level,” Government Technology, June 2017.
Specialties,” Annals of Internal Medicine, 2017,” PwC Health Research Institute, June
December 2016. 2016.
4
“Open data in drug discovery and
development: lessons from malaria,” Nature, 18
“Study: Physicians spend nearly twice as much 34
“Intel Healthcare Innovation Barometer,” Intel,
August 2016.
time on EHR/desk work as patients,” AHA December 2013.
5
“New technologies are accelerating drug News Now, September 2016.
35
“Health Care Breach Charts,” Davis Wright
development, bringing hope to patients,” 19
“How Big Data Keeps Transforming Health- Tremaine LLP Privacy and Security Law Blog,
Elesevier, June 2016.
care,” LinkedIn, May 2017. March 2017.
6
“Memorial Sloan Kettering’s Expertise 20
“Deep learning algorithm does as well as 36
“Why are doctors burned out? Our health care
Combined With the Power of IBM Watson
dermatologists in identifying skin cancer, ” system is a complicated mess,” Stat News,
is Poised to Help Doctors Make Better
Stanford News, January 2017 December 2016.
Treatment Choices,” Memorial Sloan Kettering
Cancer Center, January 2014. 37
“We asked people how to fix EMRs, and boy
21
“Biomedical Data Science Initiative,” Stanford
news, July 2015. did they have answers,” Health care IT News,
7
“Microsoft partners with UPMC, launches
May 2017.
patient engagement, population health 22
“Worldwide Semiannual Cognitive/Artificial
initiatives,” Healthcare IT News, February 2017. 38
“Big Data Experts in Big Demand,” Data Center
Intelligence Systems Spending Guide,” IDC,
September 2016. Knowledge, May 2017
8
“The Digital Universe of Opportunities: Rich
Data and the Increasing Value of the Internet 39
“2017 HIMSS Leadership and Workforce Sur-
23
“Personalized Medicine (PM) Market Analysis
of Things,” EMC Digital Universe with Research vey,” Healthcare Information and Management
By Product (PM Diagnostics, PM Therapeutics,
and Analysis by IDC, April 2014. Systems Society, February 2017.
Personalized Medical Care, Personalized
Nutrition & Wellness) And Segment Forecasts
9
“U.S. Consumer Technology & Sales Forecasts 40
“Health System Analytics: The missing key to
To 2022,” Grandview Research, June 2016.
2012-2017,” Consumer Technology Association, unlock value-based care,” Deloitte, September
May 2016. 2015.
24
“France Plans to Invest €670M in Genomics,
Personalized Medicine,” GenomeWeb, June
10
“Gartner Says Worldwide Wearable Devices 41
“Does Preventive Care Save Money? Health
2016.
Sales to Grow 18.4 Percent in 2016,” Gartner, Economics and the Presidential Candidates,”
February 2016. New England Journal of Medicine, February
25
“World Market for Telehealth – 2014 Edition,”
HIS, January 2014. 2008.
11
“The Wearable Life 2.0: Connected living in a
wearable world,” PWC Consumer Intelligence 42
“Economic Benefits of Preventing Disease,”
26
“How Telemedicine Is Transforming Health
Series, 2016. United States Surgeon General, January 2015.
Care,” The Wall Street Journal, June 2016.
12
“We Can Improve At-Home Lab Tests - Here are 43
“Payer-Provider Collaboration in Accountable
27
“How Stanford achieved 60% telehealth
3 ways direct-to-consumer testing can better Care Reduced Used and Improved Quality
adoption at a primary care clinic,” The
serve consumers’ health needs,” U.S. News & in Medicare Advantage Plan,” Aetna, Health
Advisory Board, March 2016.
World Report, June 2016. Affairs, 2012.
28
“Telemedicine Factsheet,” Novartis Founda-
13
“The Health Literacy of America’s Adults: 44
“Is Implementation of the Care Transitions
tion, 2016.
Results from the 2003 National Assessment of Intervention Associated with Cost Avoidance
Adult Literacy,” U.S. Department of Health and 29
“Google designed Android Go to win over After Hospital Discharge?” Journal of General
Human Services, 2003. the next billion smartphone users in the Internal Medicine, March 2014.
developing world,” Quartz, May 2017.
14
“Wearable sensors can tell when you are 45
“How Doctors Rate Patients,” The Wall Street
getting sick,” Stanford Medicine, January 2017. Journal, May 2014.
18
med.stanford.edu/healthtrends