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She has developed episodic ‘fits’ where she falls down consult revealed no significant abnormalities. By the
and sometimes develops thrashing movements of her next day, she was talkative and except for a few sore
legs (although she has never bit her tongue or become ribs, cheerful.
incontinent of urine or feces). She has no prior psy- She was discharged home on Day 7 of her hospital
chiatric history. stay on Escitalopram 10 mg a day and Clonazepam
Detailed interviews with her family and later with 2mg at bedtime. On her first outpatient clinic visit a
her reveal that she was pressured by her family to week after her hospital discharge, she was doing well.
become engaged to a cousin a year before the symp- She reported one incident where her tongue ‘twisted’
toms started. She developed symptoms consistent with after an argument with a family member but recovered
Major Depressive Disorder, Single Episode. She recei- spontaneously. Her Clonazepam was tapered down to
ved no treatment. Subsequently, there was family con- 1mg at bedtime with no adverse effects. Her dep-
flict and at one point, her father considered leaving his ressive symptoms continued to improve and she remai-
wife and asked Ms. Y to choose between him and her ned free of conversion symptoms. Two months later
mother. Her symptoms started at this point. her symptoms were in remission and she was consider-
Ms. Y was admitted for treatment of depression ing several offers of marriage.
and Conversion Disorder. She had no history of seizu-
res, fever, substance abuse, focal neurological signs
suggesting a neurological illness or any other signs or Discussion
symptoms suggestive of a medical or neurological ill-
ness. Patients with Conversion Disorder present a diagnostic
Routine labs at our hospital revealed hemoglobin and management challenge. A careful psychiatric his-
of 12.9 mg/dl, total leukocyte count of 4500, serum tory and examination can identify the onset and nature
electrolytes, renal and liver function tests, urinalysis, a of symptoms and the presence of stressors (if any).
chest X-ray and CT Scan without contrast were all Often, psychological stressors are hard to find because
normal. a patient with conversion symptoms is not often able
We made a presumptive diagnosis of Major Dep- to explain psychological factors themselves – this
ression, Single Episode, severe, without Psychotic fea- being the reason that they need (albeit unconsciously)
tures as well as Conversion Disorder, with Mixed Pre- to express them as bodily symptoms.
sentation. A core feature of Conversion Disorder is the abse-
We started her on a combination of Escitalopram nce of a neurological or organic diagnosis. A recent
10 mg a day to treat her depressive symptoms, Clona- study7 reviewed 73 consecutive patients with neurolo-
zepam 2 mg at bedtime to assist with sleep along with gically unexplained symptoms and found a low inci-
daily individual and family therapy. She responded dence of neurological conditions that might have ex-
well and by day 2 of her hospital stay, she was eating plained their initial symptoms (3 out of 69 patients).
better and talking. She reported improved sleep and no Seventy – five percent of their sample had a psychi-
‘fits’ since admission. atric diagnosis (predominantly affective, anxiety, or
On day 3 of her hospital stay, she was visited by somatization disorders) at presentation, and 45% were
several family members including some who had pres- diagnosed with a personality disorder. In a follow-up
sured her to marry. Later that afternoon, she became study by Binzer and Kullgren8, none of the 30 patients
agitated and had a prolonged ‘fit’ where she held her with Conversion Disorder was subsequently reclassi-
breath and developed tonic contraction of her limb fied as suffering from a neurological disease.
muscles, neck and back to the extent of bending her Factors associated with a good prognosis include
back like a bow. The episode lasted about 5 minutes male gender, acute onset, short duration of symptoms,
and was associated with shallow and rapid breathing. an acute precipitating event, change in marital status
There were no other signs or symptoms suggestive of a (either marriage or divorce), premorbid psychiatric
seizure. The doctor on duty (not a psychiatrist) gave diagnosis, good premorbid health, and the absence of a
her intravenous Diazepam and her blood pressure coexisting medical condition. In contrast, poor prog-
dropped to 70 systolic. She developed respiratory dep- nosis is associated with subclinical personality patho-
ression; a code was called and she was given CPR and logy, coexisting medical illness, poor perception of
transferred to the Emergency Department of our hos- their own wellbeing, and a high score on the Beck
pital where an EKG, routine labs and a Cardiology Hopelessness Scale and pending litigation. In children,