THE SMART

BEHIND
SEPARATIONS

HS 2400™ Headspace Sampler

Pressure Balanced for Ultimate Precision
 Connected Into the GC Workflow -
In or Outside the Lab
Labs with high sample volumes are facing growing challenges to streamline operations –
without compromising accuracy of results – all while dealing with increasingly sophisticated
technologies and high staff turnover.

The PerkinElmer HS 2400™ Headspace Sampler, part of the PerkinElmer GC 2400™ Platform,
delivers new levels of performance and ease of use that address these challenges. Because it
is integrated into the GC workflow, the HS 2400 Headspace Sampler communicates directly
with the PerkinElmer GC 2400 System. The integrated technology allows users to access
live status information from the detachable touchscreen, in and outside the lab. Proprietary
pressure-balanced technology, combined with intuitive SimplicityChrom™ Chromatography
Data System (CDS) Software, makes the HS 2400 Headspace Sampler ideal for labs looking
to optimize method development – and minimize reruns and downtime.

Experience the Innovative HS-GC workflow with the smart, simplified,

sustainable GC 2400 Platform.

Smart. Simplified. Sustainable.

SMART SIMPLIFIED SUSTAINABLE

CONNECTIVITY OPERATIONS SOLUTION

 Integrated analytical  Best chromatographic  Reduced gas consumption

workflow
 Remote connectivity for
live system status and
basic control
 Quick on-the-go decisions
with live status updates
conditions with automated with smart gas management
pressure and flow control of  Safely use hydrogen as the
HS with GC carrier gas, with optional
 Workflow-driven, built-in H2 sensor
intuitive functions with
SimplicityChrom CDS
Software
 Easy access to maintenance

www.perkinelmer.com/HS 2400 Headspace Sampler

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 HS 2400™ Headspace Sampler - Pressure Balanced for Ultimate Precision

The Right Balance for Method

Development and Routine Analysis
The unique pressure balanced sampling technology provides unmatched repeatability. Whether you are selecting a specific time
for sampling or defining a volume of sample to inject, the system delivers accurate, precise sampling. Pressure balanced technology
lets you change injection volume for each sample within a sequence, to optimize method development.

Plus, this technology allows samples to be introduced into the column without a gas syringe, fixed volume loop, or multiport
valves. Instead, carrier gas pressures are precisely regulated to manage transfer, eliminating sources of variability and
contamination found in other systems.

How Pressure Balanced Sampling Technology Works

Standby Pressurization Sampling

The heated needle area is
flushed with carrier gas
to remove contamination.
Because the column or transfer
line is inserted to the needle,
maximum inertness and
minimal dead volume
are maintained.
All vials are pressurized to
the same degree. Optimal
reproducibility and precision
are achieved regardless of
equilibration pressure in
the vial.
A solenoid valve interrupts
the carrier gas flow, and the
vial acts as a reservoir of gas.
During injection, as pressure
decays, sample volume is
transferred to the column,
preventing carrier gas from
diluting the sample and
avoiding sample expansion
before injection.

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Technology for Ultimate Precision
The HS 2400 Headspace Sampler employs an array of proven technologies that deliver outstanding precision in any application.
When the previously mentioned pressure balanced technology is married to our new air bath oven the overall result is superior
repeatability for every compound in every run.

The HS 2400 Headspace Sampler features a 12-position oven that provides ultrastable, uniform thermostatting. Built with an
air bath, the oven distributes heated air that hits target temperatures fast, with the highest stability. Circulating air eliminates
temperature variations, providing a consistent vapor equilibration that ensures reliable, repeatable results.

Overlapping Thermostatting
The vial oven accommodates 12 samples simultaneously, allowing the next sample to be analyzed as soon as the previous one is
complete, substantially decreasing overall run time while boosting productivity.

Programmable Pneumatic Control

The HS 2400 Headspace Sampler has the "best of both worlds" pneumatic control, the classic pressure control to comply
with your existing HS methods and flow control that can help to reduce carrier gas consumption while minimizing method
development. Both modes available with the programmable pneumatic control in every HS 2400 Headspace Sampler.

Multiple Headspace Extraction (MHE)

MHE is available for specific applications, with up to 100 extraction steps with intermediate automated venting. This allow
maximum operational flexibility when dealing with difficult samples like polymers.

Overlapping Thermostatting

www.perkinelmer.com/HS 2400 Headspace Sampler

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 HS 2400™ Headspace Sampler - Pressure Balanced for Ultimate Precision

Technology for Increased Sample Throughput

Typical repeatability of Ethanol, 10 injections: 0.55%

Area RSD, and 0.0026% Retention Time RSD

Vial Shaking
The system comes with a vial shaker with various intensity settings, so all samples in the oven can be agitated. Samples reach
equilibrium faster, reducing thermostatting times and increasing throughput.

Injection to Injection (PII) Optimization

Time between injections is automatically calculated for ideal sample throughput, keeping the analyses flowing smoothly
and efficiently.

Hydrogen Carrier Gas

The hydrogen carrier gas option reduces costs and addresses safety concerns without compromising performance. The sampler
includes a built-in hydrogen sensor that communicates with control software to put the system in safety mode if needed.

Single-Row Vial Tray

The HS 2400 Headspace Sampler mid-capacity has a single row vial tray making each vial easy to see at all times. This makes
sample placement, tracking and removal easy.

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Precision for Method Development
and Routine Analysis – with Any
GC System
The HS 2400 Headspace Sampler is a standalone unit that can be connected to any GC system. When it is connected to a
PerkinElmer Clarus® or third-party GC System, you control and monitor the Headspace Sampler through a dedicated, removable
touchscreen tablet, running the Simplicity Vision™ browser interface.

With the detachable touchscreen, the HS 2400 headspace sampler can be controlled in wireless mode – from sequence setup
to analysis start/stop, which optimizes your time and boosts your productivity. Control from third-party CDS software, including
Waters Empower™ CDS Software, enables better integration of the system into existing third-party CDS software installations.

www.perkinelmer.com/HS 2400 Headspace Sampler

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 HS 2400™ Headspace Sampler - Pressure Balanced for Ultimate Precision

Software and Service Bring It

All Together
Visualize Better Efficiency
Simplicity Vision is a browser interface that provides flexible
access to the GC 2400 Platform. The technology allows for
real-time status updates and monitoring of every step of the
GC workflow as well as instrument setup and prerun manual
operations. When used as a single or multi-instrument
interface, you can work remotely and make decisions on
the go.

Simplicity Vision App at a Glance

 Assess instrument readiness status  Direct instrument operations
 Check GC methods and sequences status  Browse consumables and accessories

Designed with Simplicity in Mind

The HS 2400 Headspace Sampler and GC 2400 Platform deliver
smart features, automated processes, and flexibility, driven by
SimplicityChrom CDS Software.

SimplicityChrom CDS software truly connects and integrates all

steps of the GC workflow in a way that simplifies your processes.
It’s intuitive and flexible, enabling you to achieve your analytical
goals and get results quickly. For labs that test highly regulated
samples such as pharmaceuticals and food, SimplicityChrom
CDS software supports compliance with 21 CFR Part 11.

SimplicityChrom CDS Software at a Glance

 Modern design, user-friendly iconography  Powerful search and filter features
 Easy-to-learn workflows for any skill level  Supports and facilitates 21 CFR Part 11 compliance
 User account and profile management

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Headspace Technology Applied
The HS 2400 Headspace Sampler supports the most challenging headspace analysis enabling improved method development,
also allowing an enhanced user experience with simplified operations.

Compliant Confident Food Quality

Pharmaceutical Analysis and Safety Testing
The ideal sample-preparation Delivers uncompromising
instrument for determination of accuracy, repeatability, and
residual solvents by U.S. robustness – fewer sample
Pharmacopeia Chapter 467, reruns and downtime.
Method IV.
 Edible Oils Fat Profile
 USP 467
 Alcohol in Food
 Pharma Additives

Accurate, Efficient Efficient QA/QC for

Environmental Analysis Industrial Analysis
Yields outstanding results when From the determination of
determining contaminants in solvents in paints to food
complex samples. packaging analysis, automated
and accurate analysis.
 EPA 8260
 EPA 524  Solvents QA
 EPA 624  Packaging QA
 Solvents in Paints
 E85 Ethanol in Fuel

www.perkinelmer.com/HS 2400 Headspace Sampler

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 HS 2400™ Headspace Sampler - Pressure Balanced for Ultimate Precision

The Right Consumables

for Your Analysis
The innovative design and smart features of the GC 2400 Platform
make it easier than ever for cutting-edge labs to access, operate,
and monitor their gas chromatographic separations – separations
made from the reliable, reproducible, and rugged columns that are
the heart of any GC instrument.

Whether your analytes are volatile or semivolatile, polar or nonpolar,

at high concentrations or at ultratrace levels, we’ll help you select
the best column to separate and accurately quantitate your sample
– injection to injection, column to column. Plus, we offer a variety
of stationary phases and column dimensions to fit your unique
analytical needs.

Starting with our most popular GC column part numbers, we’ve

invested in original in-house column manufacturing capabilities to
bring you a new level of reliability and performance. Each new GC
2400 is shipped with a PerkinElmer-made column to make sure your
instrument – and your analysis – start off right at the very beginning.

But we don't stop at columns. We offer a complete line of vital

consumables to support your analytical workflow. Each consumable
is carefully chosen and engineered to give you the best results.

Consumables at a Glance
 A complete line of GC columns for a wide range
of applications
 Instrument consumables specifically engineered for
optimal performance
 Consumables and accessories for preventative
instrument maintenance
 Consumables to support the entire workflow, from
sample preparation to detection

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At Your Service
A true analytical workflow cannot exist without dedicated
support – every step of the way. We’re here to help
maximize your GC workflow, from beginning to end.

Trust in Our Expertise

Instrument Services
n Optimize for uptime
n Enhance productivity
n Routine and scheduled maintenance
n Compliance with regulatory standards

Compliance Services
n Instrument qualification
n Data integrity
n Computerized system validation (CSV)

Education Services
n Classroom and online training
n Basic on-site training
n Advanced on-site training

www.perkinelmer.com/HS 2400 Headspace Sampler

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 For more information visit www.perkinelmer.com/HS2400

For more information visit www.perkinelmer.com/GC2400Platform

PerkinElmer U.S. LLC

710 Bridgeport Ave.
Shelton, CT 06484-4794 USA
(+1) 855-726-9377
www.perkinelmer.com

For a complete listing of our global offices, visit www.perkinelmer.com/ContactUs

Copyright ©2023, PerkinElmer U.S. LLC. All rights reserved. PerkinElmer® is a registered trademark of PerkinElmer U.S. LLC. All other trademarks are the property of their respective owners.

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