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Sir Frank Macfarlane Burnet and

Peter Medawar were awarded the


Nobel Prize in 1960 for their
groundbreaking discovery of
acquired immunological
tolerance. This important finding
revolutionized our understanding
of the human immune system and
has had a profound impact on
medical science. Burnet and
Medawar's work laid the
foundation for advancements in
organ transplantation and the
development of
immunosuppressive drugs.
Their research showed that the
immune system is capable of
recognizing and developing
tolerance to its own cells,
preventing the body from
attacking itself. This discovery has
paved the way for new
approaches to treating
autoimmune diseases and has
been instrumental in improving
the success rates of organ
transplants.

In their award-winning research,


Burnet and Medawar
demonstrated that acquired
immunological tolerance is a key
factor in the body's ability to
distinguish between self and non-
self, which has significant
implications for understanding
the mechanisms of immune
responses and the development
of vaccines.

The impact of their work on the


field of immunology cannot be
overstated, and their findings
continue to inspire and inform
research in the medical
community to this day. As a
teacher, I highly recommend this
book to anyone interested in the
history of immunology and the
remarkable contributions of Sir
Frank Macfarlane Burnet and
Peter Medawar to our
understanding of acquired
immunological tolerance. Their
work has left an indelible mark on
the field of medicine and has
undoubtedly saved countless lives

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