Shane Wilkerson

FRENCH

FRENCH_182_PRESENTATION
The Abderhalden chemical reaction was a origin examination for pregnancy developed by
Emil Abderhalden .In 1909 Abderhalden found that on designation of a foreign protein in
the profligate , the body reacts with a `` defensive fermentation '' ( in Bodoni footing , a
protease reaction ) that causes disintegration of the protein .He developed the test in
1912 .This test became a topic of contention soon after its evolution , and a meaning body of
work was published both in support of and refuting the test 's reliability .One such
publication concluded `` ... the item-by-item variation of both fraught and non-pregnant
blood serum make the results from both overlap so completely as to render the response ,
even with quantitative proficiency , absolutely indecisive for either positive or minus
diagnosing of gestation . ''( vanguard Slyke et al .1915 ) .The test 's boilers suit unreliability
led to its being superseded in 1928 by the Aschheim–Zondek test .Due to Abderhalden 's
gamy reputation , it was not internationally acknowledged until long after his death that the
underlying hypothesis of `` defensive attitude enzymes '' ( Abwehrfermente ) was entirely
fraudulent ( Deichmann & Mü ller-Hill 1998 ) .== References == Deichmann , U .& Mü ller-Hill
, B .( 1998 ) : The fraud of Abderhalden 's enzymes .Nature 393:109-111 .HTML abstract
Firkin , B. G. & Whitworth , J .A .( 1987 ) : dictionary of Medical Eponyms .Parthenon
Publishing .ISBN 1-85070-333-7 Van Slyke , Donald D. ; Vinograd-Villchur , Mariam ; and
Losee , J.R. ( 1915 ) : The Abderhalden chemical reaction .Journal of Biological Chemistry 23
( 1 ) :377-406 .PDF fulltext Archived 2007-09-29 at the Wayback Machine experimental
evidence of the unreliability of the Abderhalden pregnancy test Who Named It ?