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Support for this study was provided from a Behavioral Therapy Development grant from the
National Institute on Drug Abuse (R01 DA10012-01) to Samuel A. Ball.
The preliminary data from this study were presented at the June 1998 annual meeting of the
College on Problems of Drug Dependence in Scottsdale, Arizona, and final results were pre-
sented at the 6th International Congress of the International Society for the Study of Person-
ality Disorders in Geneva, Switzerland, September, 1999.
The authors thank William O’Neill for his help with data collection and management.
From the Department of Psychiatry, Yale University School of Medicine (Ball) and the Depart-
ment of Psychology, Fordham University (Cecero).
Address correspondence to Samuel A. Ball, PhD, VA CT Healthcare Center (151D), Building
35 (MIRECC), 950 Campbell Avenue, West Haven, CT 06516; E-mail: alemball@snet.net.
72
ADDICTED PATIENTS WITH PERSONALITY DISORDERS 73
critical factor for predicting Axis I disorder outcome. Rather, it may be the
range of other variables (e.g., traits, ego strength, capacity for therapeutic
alliance, symptoms, and severity) on which personality disordered individ-
uals differ that are the critical dimensions for treatment planning and out-
come.
Koerner, Kohlenberg, and Parker (1996) have proposed an alternative
diagnostic process that provides a detailed assessment of the symptoms,
problems, and theoretically based, individualized mediators of change that
are systematically linked to a behavioral therapy approach. Similarly,
Westen and Arkowitz-Westen (1999) feel that the DSM-IV Axis II should
not be used to diagnose patients in treatment for personality problems.
They suggest that this more traditional categorical approach could be re-
placed or supplemented with a more functional assessment of personality
that develops a case formulation based on the specific cognitive, affective,
interpersonal, and behavior themes or problems of each patient. In fact,
the more promising treatment approaches for borderline (Linehan, 1993)
and avoidant (Alden, 1989) personality disorder focus less on the broad,
heterogeneous Axis II categories and more on specific behavioral targets
(parasuicidal behavior and affect regulation for borderline; social skills
training for avoidant). Other recent personality disorder psychotherapies
focus at the level of personality traits (Paris, 1998), relational patterns
(Benjamin, 1993; Magnavita, 1997), and schemas (Beck et al., 1992;
Young, 1994) as points of intervention for these complex disorders.
In Dual Focus Schema Therapy (Ball, 1998; Ball & Young, 2000), per-
sonality traits are regarded as heritable dispositions that influence the ac-
tions of early caregivers. Repetitive, dysfunctional behaviors on the part of
early caregivers contributes to the development of unconditional, negative
views of self, others, and the world. These early maladaptive schemas can
lead to personality-related problems in one of several ways. First, the expe-
rience of these belief systems can trigger depressive, anxiety, or anger
symptoms. Second, early maladaptive schemas may predispose individu-
als to seek problematic intimate, social, and occupational relationships
that reinforce the strength of the schema. Third, because the experience of
the affect and memories associated with early maladaptive schemas is dis-
tressing, individuals develop maladaptive coping styles, including escape
or avoidance (e.g., through substance use) (Young, 1994). DFST is a man-
ual-guided individual therapy that targets the presenting symptoms (sub-
stance abuse, psychiatric, interpersonal) and their associated traits,
schemas, and coping styles through cognitive, experiential, relational, and
behavioral interventions based on a detailed case conceptualization.
This study provides a preliminary evaluation of our case conceptual-
ization by correlating the severity of the more common DSM-IV personal-
ity disorders found in our sample (antisocial, borderline, avoidant, and
depressive) with the different dimensions used to inform our treatment
approach: (a) personality traits, (b) early maladaptive cognitive schemas
and; (c) presenting problems (psychiatric, interpersonal). We based our
hypotheses on several sources of information (Beck et al., 1990; Costa &
Widiger, 1994; Livesley, 1995; Sperry, 1995). Specifically, we predicted
that antisocial severity would be related to (a) lower Agreeableness and
74 BALL AND CECERO
METHOD
PARTICIPANTS
Participants were 41 outpatients in methadone maintenance who met di-
agnostic criteria for antisocial, borderline, avoidant, or depressive person-
ality disorder diagnosis. The sample was predominantly Caucasian (85%;
13% African American; 2% Hispanic) men (46%) and women (54%) with a
mean age of 37.4 years (SD = 5.9). Participants were mostly single (46%;
32% separated or divorced; 22% married or cohabitating), 39% lived alone,
and 61% lived with family or friends. A total of 54% of participants re-
ported having no close friends. The sample was predominantly high-school
educated (median = 12 years of school, range 1–16). Although 59% re-
ported having had a skill or profession (5% managerial or professional;
37% skilled; 48% semi- or unskilled labor) and many had periods of ex-
tended employment (longest job held in months: mean = 63.8, SD = 45.5,
range 1–180), only 10% reported full-time employment as being their typi-
cal work pattern in the past 3 years or 30 days and 68% reported no work-
related income in the 30 days before baseline assessment. A total of 31 of
the 41 participants received either unemployment compensation, public
assistance, or Social Security income and over 50% reported relying on
family members for financial support.
All participants met DSM-IV criteria for opioid dependence on agonist
medication. The length of the participant’s current methadone treatment
episode was quite varied (range 1–180 months) with a mean of 23.1
months (SD = 42.1) in treatment. Participants were mostly injection drug
users by history (71%; intranasal, 27%; oral, 2%) and 47% of the sample
reported using heroin in the 30 days before assessment (37% used alcohol,
ADDICTED PATIENTS WITH PERSONALITY DISORDERS 75
34% used cocaine, 27% used tranquilizers, and 6% used cannabis in the
previous 30 days). Although all patients were primarily opioid dependent
by history, several considered these other substances to be their primary
problem in the 30 days before assessment (5%, alcohol; 5%, benzodi-
azepines; 10%, cocaine; 2%, inhalants). The average number of previous
admissions ranged from one to seven with a mean of 1.9 (SD = 1.7). Al-
though six of the 41 participants were on probation and referred to
methadone, criminal justice was not involved in the voluntary consent for
this psychotherapy study and dropping out of the protocol carried no
sanctions with criminal justice or with participation in the patient’s stan-
dard methadone treatment.
ASSESSMENTS
Personality Disorders. The Structured Clinical Interview for DSM-IV Axis II
(SCID-II; First, Spitzer, Gibbon, Williams, & Benjamin, 1994) is a semi-
structured interview used to assess personality disorders. A self-report in-
strument was given first, in which each of the 117 dichotomous items cor-
respond to a DSM-IV personality disorder diagnostic criteria. The
interviewer then queried each of the self-report “yes” responses of those di-
agnoses for which there were a sufficient number of endorsed items to
yield a possible diagnosis. The interviewer had five years experience in
SCID-II interviewing from a previous National Institute on Drug Abuse
(NIDA) funded diagnostic study that focused on distinguishing personality
disorder symptoms from the acute and prolonged effects of substances, in
addition to the behaviors required to maintain a substance abuse lifestyle
(Rounsaville et al., 1998). Videotapes were reviewed in supervision with
the first author.
Personality Traits. The NEO Five Factor Inventory (NEO-FFI; Costa & Mc-
Crae, 1992) is a 60-item questionnaire that asks participants to rate items
on a 5-point scale (1 = strongly agree to 5 = strongly disagree) and yields
scores on the five major domains of personality: Neuroticism, Extraver-
sion, Openness, Agreeableness, and Conscientiousness. The reliability and
validity of this instrument has been extensively evaluated in normal and
clinical samples (Costa & McCrae, 1992) and specifically in substance
abusers (Ball, Tennen, Kranzler, Poling, & Rounsaville, 1997). The Multiple
Affect Adjective Checklist-Revised, Trait Version (MAACL-R; Zuckerman &
Lubin, 1985) is a 132-adjective checklist that provides reliable and valid
state and trait measures of affects and has been used extensively in per-
sonality and clinical research (Lubin, Swearingin, & Zuckerman, 1996).
We only analyzed Positive Affect and Sensation Seeking trait scales be-
cause Anxiety, Depression, and Hostility were adequately covered by an-
other measure (see Brief Symptom Inventory below).
PROCEDURE
All participants were evaluated as part of a NIDA-funded behavioral ther-
apy development project that focused on the development of a treatment
manual for personality disordered substance abusers (Ball, 1998; Ball &
Young, 2000) and its comparison with a 12-Step oriented Drug Counsel-
ing. A total of 78 outpatients in methadone maintenance were evaluated
initially for eligibility for this study, which included the presence of at least
one personality disorder. In addition, patients were eligible if they were
having trouble abstaining from substances and were not acutely psy-
chotic, suicidal, homicidal, or cognitively impaired. All participants volun-
teered for the study because they reported to the methadone clinic admis-
sion or counseling staff that they were interested in receiving individual
therapy for emotional and relationship problems. Three patients were ex-
cluded because of current psychosis and three because of very low reading
ability that would have precluded completion of self-reports. A total of 31
were ineligible on account of not meeting SCID-II criteria for any personal-
ity disorder. There were no differences between participants and ineligible
patients on age, gender, race, or the duration or number of methadone
treatment episodes.
RESULTS
We focused on evaluating the severity of the four most common personality
disorders in this sample. Using the cut-off scores established for the SCID-
II, antisocial, borderline, avoidant, and depressive (appendix diagnosis
under consideration) diagnoses were found in over half of the participants
and there was a high level of multiple diagnoses in this sample (see Table
1). There was no association between age and personality disorder severity
ADDICTED PATIENTS WITH PERSONALITY DISORDERS 77
and the only gender difference was for males to endorse more antisocial
personality disorder symptoms than females, t(39) = 2.45, p < .02 (see
Table 1).
PERSONALITY TRAITS
Table 2 lists Pearson correlations between personality disorder symptom
severity (summed SCID-II interview counts) and traits as measured by the
NEO-FFI and MAACL-R. Antisocial personality disorder severity was asso-
ciated with very low Agreeableness and high Sensation Seeking. Borderline
severity was not associated with the NEO-FFI or MAACL-R traits assessed.
Avoidant severity was associated with higher Neuroticism and lower Ex-
traversion, Openness to Experience and lower Sensation Seeking and Pos-
itive Affect. Depressive severity was associated with lower Extraversion.
PRESENTING PROBLEMS
Before presenting the association between SCID-II personality disorder
severity and BSI and IIP-CX scores, we will briefly review the significant
addiction- and psychiatric-related problems faced by this severely im-
paired group of chronic patients. At the time of screening for study eligibil-
ity, approximately one-third of the sample self-reported significant symp-
toms of depression, anxiety, violent behavior, suicidal ideation or attempts
in the past 30 days; the majority had experienced these symptoms in their
lifetime. One half of the sample reported engaging in at least one HIV-re-
lated risky behavior in the past 3 months. The majority (85%) reported ex-
periencing emotional abuse as children and a significant number reported
past physical (49%) and sexual (27%) abuse. Regarding their addiction,
participants averaged over 10 years of substance abuse with polydrug
abuse common. Multiple treatments in substance abuse (Mean = 7.5) and
psychiatric (Mean = 5.0) programs and incarceration during adulthood
provided further evidence for considering this a chronic, difficult-to-treat
sample of dual disordered individuals.
The correlations between personality disorder severity and psychiatric
symptoms and interpersonal problems are listed in Table 4 (BSI) and Table
5 (IIP-CX). Antisocial personality disorder severity was associated with
higher IIP-CX Domineering, Vindictive, Cold, and lower Exploitable inter-
personal problems. Antisocial severity also was associated with BSI Phobic
Anxiety, Somatization, Hostility, Paranoia, and Psychotic Ideation symp-
toms in addition to higher frequency of substance use within the past 30
days, r(41) = .39, p < .009 and number of lifetime arrests, r(41) = .38, p <
.016. Borderline personality disorder severity was associated with Socially
Avoidant interpersonal problems and BSI Depression, Anxiety, Somatiza-
tion, Interpersonal Sensitivity, Hostility, and Paranoia. Borderline severity
also was related to a parental history of substance abuse, t(39) = 2.52, p <
ADDICTED PATIENTS WITH PERSONALITY DISORDERS 79
Antisocial .18 .27 .47** .23 .41** .29 .61*** .45** .35*
Borderline .36* .33* .31 .16 .38* .42** .40* .43** .22
Avoidant –.02 –.05 .12 .07 .01 .06 .19 .14 –.07
Depressive .21 .10 .23 .02 .04 .21 .12 .17 .19
*p < .05; **p < .01; ***p < .001, for zero-order correlations (n = 41).
.016 and a history of childhood physical, t(39) = 3.01, p < .005, and sexual
abuse, t(39) = 2.77, p < .009. Avoidant severity was related to more Ex-
ploitable interpersonal problems. Depressive severity was associated with
higher Exploitable interpersonal problems and a history of childhood
physical abuse, t(39) = 2.31, p < .026,
DISCUSSION
We presented results of an assessment of personality traits, early mal-
adaptive schemas, and presenting problems (psychiatric and interper-
sonal) in 41 opiate-dependent patients diagnosed with DSM-IV antisocial,
borderline, avoidant, or depressive personality disorders. Many of the cor-
relations between the symptom severity of these disorders and our person-
ality and interpersonal indicators were consistent with the literature
(Costa & Widiger, 1994; Livesley, 1995; Sperry, 1995) and may partly re-
flect overlap with the DSM-IV criteria. For example, antisocial personality
disorder severity was related to lower Agreeableness and Exploitability and
higher Sensation Seeking, Hostility, Domineering, Vindictiveness, and
Cold dimensions. Avoidant severity was related to higher Neuroticism and
Exploitability and lower Extraversion, Openness, Sensation Seeking, and
Positive Affect dimensions.
Of somewhat greater interest were the relations between the personal-
ity disorders and maladaptive schemas that have been hypothesized
(Beck, et al., 1990) but not previously evaluated. As predicted, antisocial
severity was related to Mistrust/Abuse and Emotional Inhibition (in addi-
funded study of Dual Focus Schema Therapy (Ball, 1998; Ball & Young,
2000). In the early phases of our treatment, the different psychiatric symp-
toms and interpersonal problems assessed in this report provide multiple
foci for behavioral interventions. Once the presenting substance abuse,
psychiatric distress, or interpersonal problems have reduced in intensity,
psychotherapeutic work can begin to integrate a focus on the core issues
and patterns (i.e., maladaptive schemas and coping styles). Early and sus-
tained therapeutic attention to current symptoms and conflicts helps re-
duce relapse risk and promotes the necessary cognitive, emotional, and in-
terpersonal stability necessary for later exploratory work. Patient trust
engendered through early resolution of at least some of the major present-
ing complaints also may permit later empathic confrontation of maladap-
tive cognitive and behavioral patterns. Both the presenting symptom-fo-
cused and associated schema-focused aspects of treatment occur with a
knowledge and appreciation of personality traits and disorders that the
therapist shares with the patient early on in treatment. We believe that
sharing a coherent, individualized conceptualization based on the mea-
sures in this report has provided the foundation from which interpreta-
tions or confrontations could be made by the therapist and accepted by
the patient.
We believe that the personality, interpersonal, and schema indicators
evaluated in this report have had much greater relevance for planning in-
terventions and educating patients about their personality and related
problems than have the DSM-IV categories. McCrae et al. (in press) have
suggested that a model combining a profile of normal-range personality
traits with an assessment of personality-related problems would be a more
reliable, valid, and treatment-relevant system for conceptualizing person-
ality disorders and should replace Axis II in future DSM revisions. Al-
though we agree with many in the field who believe that Axis II could be re-
placed by a dimensional model of personality disorder, we believe that it
would cause unnecessary confusion to drop it completely from the treat-
ment planning or research investigation process unless clinicians and sci-
entists become completely familiar with an alternative model. Until then, it
provides an important anchor for communication between clinicians and
patients and between researchers and funding agencies, in addition to
serving as the system against which alternative models can be compared.
For this reason, we chose to map out the validity of our theoretical indica-
tors onto four of the most common Axis II categories found in substance
abuse samples.
REFERENCES
Alden, L. (1989). Short-term structured sonal Problems. Journal of Personality
treatment for avoidant personality dis- Assessment, 55, 521–536.
order. Journal of Consulting and Clini- American Psychiatric Association. (1994). Di-
cal Psychology, 56, 756–764. agnostic and statistical manual of men-
Alden, L. E., Wiggins, J. S., & Pincus, A. L. tal disorders (4th ed.). Washington,
(1990). Construction of circumplex DC: Author.
scales for the Inventory of Interper- Ball, S. A. (1998). Manualized treatment for
82 BALL AND CECERO
substance abusers with personality Livesley, W. J. (Ed.). (1995). The DSM-IV per-
disorders: Dual Focus Schema Thera- sonality disorders. New York: Guilford.
py. Addictive Behaviors, 23, 883–891. Lubin, B., Swearingin, S. E., & Zuckerman,
Ball, S. A., Tennen, H., Poling, J. C., Kran- M. (1996). Research with the Multiple
zler, H. R., & Rounsaville, B. J. (1997). Affect Adjective Checklist and the Mul-
Personality, temperament, and char- tiple Affect Adjective Checklist-Revised.
acter dimensions and the DSM-IV per- San Diego, CA: Educational and In-
sonality disorders in substance dustrial Testing Service.
abusers. Journal of Abnormal Psychol- Magnavita, J. J. (1997). Restructuring per-
ogy, 106, 545–553. sonality disorders: A short-term dy-
Ball, S. A., & Young, J. E. (2000). Dual focus namic approach. New York: Guilford.
schema therapy for personality disor- Marlatt, G. A., & Gordon, J. R. (1985). Re-
ders and substance dependence: Case lapse prevention. New York: Guilford.
study results. Cognitive and Behav- McCrae, R. R., Yang, J., Costa, P. T., Jr.,
ioral Practice, 7, 270–281. Dai, X., Yao, Cai, & Gao, B. (in press).
Beck, A. T., Freeman, A., & Associates. Personality profiles and the prediction
(1990). Cognitive therapy of personality of categorical personality disorders.
disorders. NY: Guilford. Journal of Personality,
Benjamin, L. S. (1993). Interpersonal diagno- Paris, J. (1998). Working with traits: Psy-
sis and treatment of personality disor- chotherapy of personality disorders.
ders. NY: Guilford. Northvale, NJ: Aronson.
Costa, P. T., & McCrae, R. R. (1992). Revised Phillips, K. A., Hirschfield, R. A. M., Shea, M.
NEO Personality Inventory and NEO T., & Gunderson, J. G. (1993). Depres-
Five Factor Inventory. Odessa, FL: Psy- sive personality disorder: Perspectives
chological Assessment Resources. for DSM-IV. Journal of Personality Dis-
Costa, P. T., Jr., & Widiger, T. A. (Eds.). orders, 7, 30–42.
(1994). Personality disorders and the Rounsaville, B. J., Kranzler, H. R., Ball, S.,
five factor model of personality. Wash- Tenne, H., Poling, J., & Triffleman, E.
ington, DC: American Psychological (1998). Personality disorders in sub-
Association. stance abusers: Relation to substance
Derogatis, L. R. I. (1992). The Brief Symptom use. Journal of Nervous and Mental
Inventory. Baltimore: Clinical Psycho- Disease, 186, 87–95.
metric Research. Sanislow, C. A., & McGlashan, T. H. (1998).
First, M. B., Spitzer, R. L., Gibbon, M., Treatment outcome of personality dis-
Williams, J. B. W., & Benjamin, L. orders. Canadian Journal of Psychia-
(1994). Structured Clinical Interview for try, 43, 237–250.
DSM-IV Axis II (v. 4), New York: Bio- Schmidt, N. B., Joiner, T. E., Young, J. E., &
metrics Research Department. Telch, M. J. (1995). The Schema Ques-
Horowitz, L. M., Rosenberg, S. E., Baer, B. tionnaire: Investigation of psychomet-
A., Ureño, G., & Villaseñor, V. S. ric properties and hierarchical struc-
(1988). Inventory of Interpersonal ture of a measure of maladaptive
Problems: Psychometric properties schemas. Cognitive Therapy and Re-
and clinical applications. Journal of search, 19, 295–321.
Consulting and Clinical Psychology, 56, Sperry, L. (1995). Handbook of diagnosis and
885–892. treatment of the DSM-IV personality
Koerner, K., Kohlenberg, R. J., & Parker, C. disorders. NY: Brunner/Mazel.
R. (1996). Diagnosis of personality dis- van Velzen, C. J. M., & Emmelkamp, P. M.
order: A radical behavioral alternative. G. (1996). The assessment of person-
Journal of Consulting and Clinical Psy- ality disorders: Implications for cogni-
chology, 64, 1169–1176. tive and behavior therapy. Behaviour
Lee, C. W., Taylor, G., & Dunn, J. (1999). Research and Therapy, 34, 655–668.
Factor structure of the Schema Ques- Verheul, R., Ball, S., & van den Brink, W.
tionnaire in a large clinical sample. (1998). Substance abuse and person-
Cognitive Therapy & Research, 23, ality disorders. In: H. R. Kranzler & B.
441–451. J. Rounsaville (Eds.), Dual Diagnosis
Linehan, M. (1993). Cognitive behavior ther- and Treatment: Substance Abuse and
apy for borderline personality disorder. Comorbid Medical and Psychiatric Dis-
New York: Guilford. orders. New York: Marcel Dekker.
ADDICTED PATIENTS WITH PERSONALITY DISORDERS 83
Westen, D., & Arkowitz-Westen, L. (1999). Young, J., & Brown, G. (1990). Schema
Limitations of Axis II in diagnosing Questionnaire (2nd ed.). Unpublished
personality pathology in clinical prac- instrument.
tice. American Journal of Psychiatry, Zuckerman, M., & Lubin, B. (1985). Manual
155, 1767–1771. for the Multiple Affect Adjective Check-
Young J. E. (1994). Cognitive therapy for per- list–Revised. San Diego, CA: Educa-
sonality disorders: A schema-focused tional and Industrial Testing Service.
approach. Sarasota, FL: Professional
Resource Exchange, Inc.