SBI242 – Week 9 Kahoot’s Quiz

Drugs affecting the Endocrine System

Q1 – Which cells in the pancreas produce insulin?

a) Alpha
b) Delta
c) Beta
d) Gamma

Q2 – Which of the following inhibits the release of insulin?

a) Incretins
b) Glucagon
c) Somatostatin
d) Beta adrenoceptor stimulation

Q3 – Which of the following is NOT a sign and symptom of diabetes?

a) Increased urine output (polyuria)

b) Fruit breath odour (ketosis)
c) Excessive thirst (polydipsia)
d) Reduced appetite

Q4 – Complications of diabetes include all of the following EXCEPT:

a) Asthma
b) Diabetic neuropathy and retinopathy
c) Atherosclerosis
d) Thrombosis

Q5 – Which of the following drugs can cause hypoglycaemia?

a) Glucocorticosteroids
b) Loop diuretics
c) Glucagon
d) ACE inhibitors

Q6 – Which of the following is a sign/symptom of hypoglycaemia?

a) Polydipsia
b) Cold sweats and confusion
c) Polyphagia
d) Polyuria

Q7 – Which of the following is NOT a component of ‘metabolic syndrome’?

a) High serum triglycerides

b) Low high-density lipoprotein cholesterol level
c) Elevated fasting blood glucose
d) High high-density lipoprotein cholesterol level
Q8 – Metformin is a biguanide oral hypoglycaemic agent. Which of the following is NOT one of its
functions?

a) Increases glucose uptake and utilisation in skeletal muscle

b) Reduce the number of insulin receptors
c) Reduce low- and very low-density lipoproteins
d) Reduce glucose production in the liver

Q9 – What is the mechanism of action of sulfonylureas in the treatment of type 2 diabetes?

a) Block potassium channels, causing increased insulin secretion from the pancreas
b) Block potassium channels, causing decreased insulin secretion from the pancreas
c) Activates potassium channels causing increased insulin secretion
d) Activates potassium channels, causing decreased insulin secretion

Q10 – Which of the following is NOT a typical adverse reaction of Thiazolidinediones.

a) Anaemia
b) Weight loss
c) Peripheral oedema
d) Increased risk of heart failure

Q11 – Dapagliflozin is a selective, reversible inhibitor of SGLT2 in the renal tubules. One of its
adverse effects is:

a) Hypervolaemia
b) Fluid retention
c) Hypovolaemia
d) Increased weight gain

Q12 – Which of the following adverse reactions is NOT associated with corticosteroid over-use?

a) Fat redistribution
b) Improved wound healing
c) Weight gain
d) Muscle wasting

Q13 – What is one of the main functions of the thyroid hormone?

a) Regulates saliva production

b) Regulates urine output
c) Regulates acid production
d) Regulates carbohydrate, lipid and protein metabolism

Q14 – High levels of circulating TSH in the blood indicate:

a) over-production of thyroid hormone.

b) under-production of FSH (follicle-stimulating hormone).
c) under-production of thyroid hormone.
d) over-production of FSH.

Q15 – Clinical signs and symptoms of hyperthyroidism include:

 a) fatigue and lethargy.
b) husky voice.
c) swelling/fullness in the neck (goitre).
d) cold intolerance.

Q16 – The main indication for thyroid medication ‘Thyroxine’ is to treat:

a) hyperglycaemia.
b) hyperlipidaemia.
c) hyperthyroidism.
d) hypothyroidism.

Q17 – A patient is taking both insulin (Type 1 Diabetic) and an ACE inhibitor for high blood
pressure. What could be a concern?

a) Risk of hyperlipidaemia
b) Risk of hypertension
c) Risk of hypoglycaemia
d) Risk of hyperglycaemia