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    Brîndușa Petruțescu
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    AlergiaVopseadepar

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    4 views23 pages

    Alergia Vopseadepar

    Uploaded by

    Brîndușa Petruțescu

    Copyright:

    © All Rights Reserved
    Download as PDF or read online from Scribd
    Flag for inappropriate content
    of 23
    ree Prt cre ncaa ny hare PPD: the most common cause of ACD to hair cosmetics PPD: cea mai frecventa cauza de DCA la cosmeticele pentru par 25% dintre cauzele de DCA indus de produsele cosmetce pentru par (40% din cauzele de dermatia scalpului) Te > DCI contact prelungt,prutit non histarinergc prin MRGPRXZ UC sau ANA, chiar reaci anaflactode la 16 ote la testare patch ‘Scanat cu CamScanner Prot aera mame eg hati be drape estate rer pesetace a orereae eos Temporary non-oxidative hair dyes Vopsele de par neoxidative temporare “forme cosmetice: gampon, gel, emulse 4 soluje «nivel vopsire: 0 prin depoztare pe supratta fru de pir (li penetvare a cortexuiui), rezst la 1-3 spBlari oe Colorantl aclal cu GM mare neinclug tn sere patch comercial Foxx “OL, * colorant prazofc!. Galben acid 23 (tarrazin8) 2% pet alergen de contact nesemnificativ ~ Some ‘colorant monoazoic. Roqu acid 33 0.5% pet alergen de contact nesemnificativ Ts ~ + colorant antrachinonict Violet acid 43, 1 ptaerpen contac posts CI Bead Ctra ergy 2521002 Dae ID J Cou Ded 822 ‘Scanat cu CamScanner — Proven eaesrmcresil ep dere te apn erase perl prance went ty | Chemical semi-permanent nonoxidative hair dyes Vopsele de par neoxidative semipermanente chimice + forme cosmetic: lfun, sampoane, spuma $i emusi «nivel vopsie: 1 cu interacfuni once, fore van der Waals, penetrare redus& in cortex, rezistA pnd la 6-7 spAlari \opselele semipermanente pot imbundtay temporar tonul elo prulu, Utlzate impreund cu cele demipermanente pot acjona ca nuanfatoare ton-pe-ton Coloranfi bazici GM micé neindugitn serie patch comerciale: + colorant azoic: maro bazic 17 1% aq (UC; ANA), rogu bazie 22 1% 0q (1 caz DCA) = + colorant naflochinonct:lbastru bazc 99 1% ag (UC; ANA) e Colorantinitroanilinici rogu inchis-maro: ees Se. + 2nitro-PPD 1% pet HDS (CRICS <10% PPD) OC a He + Znit-PAP (4-amino-3-itrotenol 1% pet (éela producitor HD") + 3. HO-ELPAP (Bnitephidoset aminfenol) 1% pet (dela producdtor HD") E * compusi niroanilnic f6rd CR cu PPD sau PAP Sabet Cr rat (0) 2D: Fats Ret a CD 2 Sn etl CO 7S Duane Cn Ep nee 20 nen eee Ketel 7014 etl CO 2016 Scanat cu CamScanner Natural herbal colourants for semi-permanent hair dyeing Coloranti naturali din plante pentru vopsire semipermanenta a parului awsona (2-hidroxi-1,4-naflochinond) frunze Lawsonia inemmis 9; patch henna 10% ag, lawsona 5% pet (rar DCA, ANA) oo" a henna neagré cu PPD Y _sensbiizre la tiner cu DCA tatujetemporareartzanale™ si vopsir oxidalivs a pul * preparatele cu henna comerciale contin sale amine aromatice indusiv PAP etc * dferte de tatuaje temporare cu fruct jagua (Genipa americana) (ari PPD (genipind 1% aq) OH O jpglona (Shido 4-natochinond)nuci Juglans spp patch extrac coi de nuc8 cu juglond 1% ag (rar DCA) CO abastu indigoindgotna frunze Indigoleratinctora ‘alergen de contact foarte rar, test patch ca atare ‘ndgotna si henna apicate Impreund produc culoare brun Inchis q e fore Oe Cont omaitn ett Ooms OnatP ad Ciba oct rtrd oe be = ae! ea Cre A Carta 213 Uber KS eta JAstoneAtozy 2017 Medes 207 221 Veer Ub ete Crtrt Ooms 2050 Ca Met ‘Scanat cu CamScanner (apie escxracee gre prretity a ort rtmany | Oxidative hair dyes Vopsele de par oxidative eee \ gam fata do nuante Inchise | ‘nu foarte eficientS pe par grizonat PERMANENTE. | ‘gent acaln: etanolamina 5 | a ie 2 DoT SC Ore 2 Wien De dhe Dom 2 Lr Wt Cte Du 2% Soh Catt Cec Dame rn Scanat cu CamScanner Prsetenedceonal cece lc te ety State rayne ss cara goed peta reat tote Oxidizing agents in creams/powders for hair bleaching Agenti oxidanti din creme/pulberi pentru decolorarea parului persulfat de amoniu (APS) 2.5% pet HDS. ae Cree see eee uence Mua sa Po ee Riera kee key dar si DC! sau reacti de tip imediat (WA) UC) ANA) foe cineme cea acca eiceaiy aise sere mst cmb etn dcrmrtV OSA, sched Pal 7 Pad pg pee! ev Coben Tatty 251, Comme Dem 2002 Wate tk JA ead arma O72 er Weta Carta Ovatte 2022 Syne Cet Crtact Demat 2022 ‘Scanat cu CamScanner Prerteyeheatorarecomersibc tcp htt Stee Inapeie asexrate gover prvetaty cies rome i cremilemulsie Vopsele de par permanente revelatoare Permanent hair dyes 80% din piafa vopselelor de pir cremalgel colorant baza oxidant $1 agent de cupiare | ca 1) ! al Poses ‘Scanat cu CamScanner Prewtan eters rome tp baat ce PPD oxidation base: prohapten used for allergy patch testing Baza de oxidare PPD: prohaptena utilizata pentru testare alergologica patch nope av carace ger prtertatn wrest nla 1? intermedia p-BQD1 F . : bret ain BQ si BB nu sunt markeri de screening utli pentru alergia la vopsea de par oxidativa in locul PPD 1% pet EBS ‘< 30% din pacientii PPD+ reactioneazé la BQ 0,1% pet < 20% din pacien}i PPD+ reacjoneazd la BB 0,1% pet p-BQ ‘op-benzochinona PPo= come produce in vivo muti determinant antgenici fs Bandrowski (trimer) W1 ‘metaboiij acetiLPPD Wt esensizny When A etal Cn Ep Adorgy 2008210) 1289 Plorappan ta bran Demat Veer ee $083 407 ‘Scanat cu CamScanner Presta etsapraleecomersl cup Rat eae nape crater gre pretest 9 retires Chemical mechanisms of colour generation in oxidative hair dyes Mecanismele chimice de generare a culorii in vopselele de par oxidative ty ‘compus de tip leuco colorant dinuclear colorant trinuclear |)" slab colorant indoaniinic magenta indoaniinic brun ‘oH PAP v g 8 agent cuplare NH o leplar (0) (01 mg aa HN é "NH : ~ NH ah, mH Bool cromoforil formati sunt compusi colorali cu GM mare aes ‘efinuj tn interiorul fului de p&r precursorii colorantilor penetreazA usor cortcala frelor de par: baze de oxidare/intermediari primar oxidati tn forme reactive In mediu oxidativ combinate cu agent de cuplarefntermediani secundari in mediu alcalin Towns A. Colraton Techooogy, 2021,00:1-35, ‘Scanat cu CamScanner Presctaneeeeral cel et harey Se capris ev ence ger peraty 9 reat rtoraty Oxidation bases / primary intermediate precursors in oxidative hair dyes Baze de oxidare / precursori intermediari primari din vopsele de par oxidative p-fenilendiamine $i similare or Beale fo HAN’ PPD p-enilendiamina 1% pet EBS, HDS (vopsele permanente) BIXIHPPS hidroxietip-enilendiamina sulfat 2% pet HDS (CR PPD 10%) (vopsele permanente) 2 Ce be Neo, we PTDS p-toluendiamind/toluen-2,5-diamina sulft 1% pet HDS (CR PPD 80%) (demipermanente si permanente PPD-free) p-aminofenoli PAP p-aminofencl 1% pet HDS (CR PPD 90%) a ( — PMAP p-meSlaminofenol 1% pet HDS (permanente gi demipermanente) or” 26 4A3MP p-amino-m-crezol/4-amino-3-melilfenol 1% pet (absent in HDS) ow mprerons ami tepvrrar osson I ep ghenfemtarwe ent ‘Scanat cu CamScanner Examples of coupling _ reacting with PPD as primary intermediate {i de cuplare care reactioneaza cu PPD ca intermediar primar ain ese gre praetor me ‘Scanat cu CamScanner ge crac pore presto erate tart Prsrtrs eetradcorer tp hat Sete Cross-reactivity between haptens with para groups: limited to dyes or extended Cross-reactivitate intre haptene cu grupari de tip para: limitata la coloranti sau extinsa Intermediari primari din vopsele de par oxidative permanente sau demi-permanente: + p-fenilendiamina (PPD) 1% pel EBS, HDS NH, + TDS p-toluendiamind/toluen-2,5-diamind sulfat 1% pet HDS (CR PPD 80%) + PAP p-aminofenal 1% pet HDS (CR PPD 90%) HN + 4ASMP p-amino-m-crezol/4-amino-3-melllenol 1% pet Colorantritwoanilinc din vopsele de par semipernanente chimice: + 2-itto-PPD 1% pet HDS (posibil CR PPD) Colorant textil azoic din fibre sintetice (acetal, nailon/poliamids, poliestor) oran de ispersio 3 1% pel CTXS DOS tic, enjerie clan potocamarafbe inchs tS a! > 80-85% PPD+ sunt DO3+, 90-95% DO3+ sunt PPD+ > PPD marker al alergiei la DO3 (nu gi pentru albastru de dispersie 106 saui24) — H Antioxidant eauciue negru dur i Icon Jo ——} 4 + N-izoproplN-fenit-p-enlendiamind (IPPD) 1% pet EBS > 60% TOM> sunt BRMxe gi PPD+ & Ps yy < ol one 22 smn Te TH 8 room seston Cortana key nef ee arf Crd cme a ear Gare ba Pee Garam Corgan Coes Pra Sees biog ua ages mover eeeten demi tps Pata | EAT oe HT ‘Scanat cu CamScanner Prete cht econ es xp Ma See lapel eu corms pre poset sorta toast Cross-reactivity between haptens with para groups ‘Anestezice locale ip esler (derivali acid p-aminobenzoic/PABA): + benzocaina 5% pet (unele produse anthemoroidale si de uz topic oral) + procaina 1% pel (proflaxia fenomenelor degenerative gi crema antirid) Cross-reactivitate intre haptene cu grupari tip para i Hemorol” ae Filtre chimice UVB derivate PABA din produse de fotoprotectie + etihexil(octi}-dimetil PABA 10% pet SSS Ox 0. + etilhexil(cti) tiazond 10% pet SSS & Agent depigmentare + hidrochinona 1% pel HDS aN, Parabeni (esteri acid p-hidroxibenzoic) —— > ca biocide noneliberatoare de formaldehida (CR rara) Parabeni mix 16% pet EBS 5 cae Pinna | ] bey a Sulfonamide (CR rord) sulfanilamida 5% pet ie p=—= Pent eros Ouran Snr tn Peer Fran Ct come a met ret Sa Jeppesen sara ie rte wt Hau Pomenlh Onctieman i Corpuns i Gree Ch Paid Dewy Ai a oo Retany CE aes Hes Palit} ARAN Cw PBA SEA ‘Scanat cu CamScanner Pare excceradrecrenal emp bare deste nage crac goer petetaty 9 enetan toma PPD-free alternative hair dyes Vopsele de par alternative fara PPD qs i r if ee > Testele cutanate patch cu componente moleculare pot detecta CR gi CS pentru a putea detecta alternative mai sigure, dar webuie avut in vedere c& reactivitatea incrucigatd nu este intotdeauna relevantd din punct de vedere clinic. Sect Ho Creat erste HOB SHC) AT8: MAb KS eo Astrea ders ZIT 10015: pein At al eran 2024.21) 1321 ‘Scanat cu CamScanner nope mercer pel pests otsv my Types of permanent for hair curling and relaxer for hair straightening Tipuri de permanent pentru ondulatia parului si de relaxant pentru indreptarea parului Relaxant sau Permanent la rece de tip alcalin patch: oglicolat de amoniu (ATG) 2,5% aq HDS (ATG CR GKITG) wt, oe Permanent tioglicolat-free la rece de tip alcalin + HCI patch: cisteamina/2-mercaptoetilamina (2-MEA) clorhidrat 0,5% pet HOS. HSA ny. le Permanent la eald de tip acidic i ole patch: gfcerl monotiogicolat (GMTG) 1% pet HDS (CR ATG) = 2 ah a Cacia Gin Jet a Cotact emits 212 he amr cret 1 pacen201 SENSO chest ef perme pborg pt ten Fe at Dermat 2024 ‘Scanat cu CamScanner Prsetan eters remeca cs paar ecIe Sulphites as contact haptens in hair cosmetics Sulfitii ca haptene de contact in produse cosmetice pentru par biocid/conservant, antioxidanVagent reducdtor, agent de albire/decolorant metabisulft de sodu 1% pet EBS, HDS (disulfit/pirosutfit de sodiu) = marker peru DCA‘ a suf CR cual sufi: sult de sod, hidrosulfliiont de sodiu sulfti-alergenele anului 2024 * cel mai frecvent: dermatité faciala sau a mainior " pot induce $i react de HS imediatd (ANA, UC, ASTM) + creme colorente pentru vopsele de pr oxidative, + produse tip relaxan/permanent endotermic la pH sedzut, + yampoane gi alte cosmetice (1%) DUN a a Coa Lay ASersy 302. hats Ot ok, Cortact Dermata 2216, Covey aa | Dermatel 2018: Borges AS. Vines Cont ena 2 rye Sma Vow Ded Cones Se a ee ‘Scanat cu CamScanner Prswten estrada 8 Biocides in hair cosmetics Biocide din produsele cosmetice pentru par Formaldehida si biocide eliberatoare de formaldehida (FR) O + forrmaldehida [H-CHOFM] 2% 0q HOS Hen ‘Quaterium 15 $i FA iberd sunt interzise In cosmetice EU 0 H ° eo wAL L 208 povenfi FA» ent FR (DMPO) + azotdnl urea [DAU] 2% pet HOS Pe Ne cH SNOW manne + bromo-ntropropandal [BNPD] 0.25% pet HDS (minim FR) =O ) Cai Ariocid din cosmetice rinse-oll 40% MIT sunt CMITINIT 0.02% Biocide iztiazolinonice non-eliberatoare de formaldehida (6% InDCACSM-P) FSy,_ cy, [ 107% MIT syne CMITAMIT 0.215% + metizobazolnana [MIT] 0.2% oq EBS nepermis in cosmetce leave-on EU <, 45% CRia 2 217 + Corometitazpinens [CHIT] + Mi [3:1 CMITAMIT] 0.02% oq HDS; 0,215% aq ISS : aera Cat mete 218 Wt Cate men 22 nn Cami 321, Pr Te en 222 ee a Li ee me 2008 Ptr a Dh hed eee $e ‘Scanat cu CamScanner Pramtey edeteral comer tp katy ate rope esermse geet were eters Surfactants in shampoos, shower gels, hair conditioners with antistatic effect Surfactanti din sampoane, geluri de dus, balsamuri de par cu efect antistatic Surfactan{ineionicialchilpoliglicozidici (APG) Og {| A + deci glucozida 5% pet EBS, HDS + laurl glucazida/polighicaza 3% pet HDS (CR decil glucozida >40%) ‘Surfactanti amfotericl CG Garr | ‘amidoamina 0,1% oq ACS gi dimetilamino-propilamina (DMAPA) 1% aq ACS ° fo + cocamidopropil betaina (CAPB) 1% aq HDS: aaah Surfactan{icationici on + oleamidopropil dimetilamina 0.1% aq HDS Qe, A A Surfactantul anionic lauril sulfat de sodiu: cea mai frecventé cauz de DCI la surfactant Aah Tete Corts Demsttn 212 hon ee L0G 222; Waa Eel a AAD 222: Pn CT eal erm 22. Prey Ck ete 321; Sabon O eal Eur J Dorm 2022 ‘Scanat cu CamScanner Protea mrad vp are Ste Chemical UV filters in hair and nails cosmetics Filtre chimice UV din produse cosmetice pentru par si unghil considerate sigue cu doar cteva cazuri DCA raportate la benzofenone (BP) foiedegradat in BP ws ch Zs HB becotenons3 (P-2) 1% pet SSS ~~ spray faa, balsam pl, of provencea decolorsi i HVE cctocrilen (OCT) 10% pet SSS centons de pit evn porto [pss Inpotpemant fenofibrat 10% pet PPS ~ {ctoslerpen stem cu structs wp OP - UVA avobenzona(AVO) 10% pel SSS . (thar ni 2 a eta 2 st Cen oa nage mere pour penta rete fame Ows ANS gel ketoprotton (KP) 1% pet PRPS fotoatergen topic potent ‘Oyo ‘Scanat cu CamScanner Frortayrezerad rears tp hati de tropes sca gerd penta ore re FR1: key marker of fragrance allergy FR1: marker esential al alergiei la parfumuri 135% in DCACSHP py gy, pet TES | enc Ooms 2528 IDV, Pes CT ea Deca TLE Saks Teta Cort Deaten 20%2, 40) S14523 ‘Scanat cu CamScanner rain esa need ic ae se ph wet repent sera mae FR2: additional marker of fragrance allergy FR2: marker aditional al alergiel la parfumuri

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