Professional Documents
Culture Documents
014
Application to DNA
T T
T
0
Rational tangles: Start with 0 and twist an odd number of times: right, down, right, down, right, Start with , and twist an even number of times: down, right, down, right,
1
T
= -
1 2
3 + 1 = 2
=
2,3
Every continued fraction has a unique canonical form: a positive/negative continued fraction of odd length.
Tangles with equal fractions are equal: Bring the tangles into canonical form. The corresponding fractions are also in canonical form. The canonical form is unique for fractions, so the fractions are equal.
Rational knots
A rational knot is the closure of a rational tangle. Notation: cl(T) =
cl(3) =
Application to DNA
1.The DNA loop is twisted n times. 2.The enzyme X replaces the tangle 0 by r. 3.The result is the knot cl(10/7). 4.Determine r without knowing n.
Enzyme X
cl(1/n + r) the result is cl(10/7) nr + 1 = 10 and either n = 7 (mod 10) or 7n = 1 (mod 10) nr = 9, so n = 1, 3, 9. The possibilities are n = 3 Enzyme X acts by replacing the 0 tangle by 3