Antibiotics:

-Amoxicillin & Clavulanic Acid (Augmentin, Augmentin 600 ES, Augmentin XR) [Antibiotic/Aminopenicillin, Beta-lactamase Inhibitor] Uses: *Ear, lower resp, sinus, UTI, community acquired pneumonia, skin Infxns caused by lactamaseproducing H. influenzae, S. aureus, & E. coli* Dose: Adults. 250500 mg PO q8h or 875 mg q12h; XR 2000 mg PO q12h. Peds. 2040 mg/kg/d as amoxicillin PO q8h or 45 mg/kg/d q12h; in renal impair; take w/ food -Amoxicillin (Amoxil, Polymox) [Antibiotic/Aminopenicillin] Uses: *Ear, nose, & throat, lower resp, skin, UTI from susceptible gram(+) bacteria* endocarditis prophylaxis Dose: Adults. 250500 mg PO tid or 500875 mg bid. Peds. 25100 mg/kg/24 h PO q8h. 200 400 mg PO bid (equivalent to 125250 mg tid) -Azithromycin (Zithromax) [Antibiotic/Macrolide] Uses: *Community-acquired pneumonia, pharyngitis, otitis media, skin Infxns, nongonococcal chlamydial) urethritis, chancroid & PID; Rx & prevention of MAC in HIV* Dose: Adults. Resp tract Infxns: PO: Cap 500 mg day 1, then 250 mg/d PO 4 d. Sinusitis 500 mg/d PO 3 d. IV: 500 mg 2 d, then 500 mg PO 710 d or 500 mg IV daily 2 d, then 500 mg/d PO 710 d Nongonococcal urethritis: 1 g PO 1. Gonorrhea, uncomplicated 2 mg PO 1; Prevent MAC: 1200 mg PO once/wk. Peds. Otitis media: 10 mg/kg PO day 1, then 5 mg/kg/d days 25. Pharyngitis: 12 mg/kg/d PO 5 d (susp on empty stomach; tabs OK w/ or w/o food; w/ CrCl <10 mL/mg -Cefazolin (Ancef, Kefzol) [Antibiotic/Cephalosporin-1st Generation] Uses: * Infxns of skin, bone, upper & lower resp tract, urinary tract, endocarditis prophylaxis Dose: Adults. 12 g IV q8h Peds. 25100 mg/kg/d IV q68h; -Ceftriaxone (Rocephin) [Antibiotic/Cephalosporin-3rd Generation] Uses: *Resp tract (pneumonia), skin, bone, joint, urinary tract Infxns, meningitis, & septicemia, infxn- uncomplicated, gonococcal, conjunctivitis gonococcal, Dose: Adults. 12 g IV/IM q1224h. Peds. 50100 mg/kg/d IV/IM q1224h; decreased in renal impair -Cefotetan (Cefotan) [Antibiotic/Cephalosporin-2nd Generation] Uses: *Rx Infxns of the upper & lower resp tract, skin, bone, urinary tract, abdomen, & gynecologic system, *preferred antibiotic for battle field injuries Dose: Adults. 13 g IV q12h. -Cephalexin (Keflex, Pranixine Disperdose) [Antibiotic/ Cephalosporin-1st Generation] Uses: *Skin, bone, upper/lower resp tract, urinary tract Infxns, otits media, Dose: Adults. 2501000 mg PO qid. Peds. 25100 mg/kg/d PO qid; in renal impair; (on empty stomach)

-Ciprofloxacin (Cipro, Cipro XR, Proquin XR) [Antibiotic/Fluoroquinolone] Uses: Rx lower resp tract, sinuses, skin & skin structure, bone/joints, & urinary tract Infxns including prostatitis, anthrax, diarrhea Dose: Adults. 250750 mg PO q12h; XR 5001000 mg PO q24h; or 200400 mg IV q12h;in renal impair -Doxycycline (Adoxa, Periostat, Oracea, Vibramycin, VibraTabs) [Antibiotic/Tetracycline] Uses: Broad-spectrum antibiotic, acne vulgaris, uncomplicated GC, Chlamydia sp, PID, Lyme disease, skin Infxns, anthrax, malaria prophylaxis Dose: Adults. 100 mg PO q12h on 1st d, then 100 mg PO daily bid or 100 mg IV q12h; acne daily dosing, Chlamydia 7d, Lyme disease 1421 d, PID 14 d - Levofloxacin (Levaquin, Quixin & Iquix Ophthalmic) [Antibiotic/Fluoroquinolone] Uses: lower resp tract Infxns, sinusitis, chronic bact prostatitis, pyelonephritis, UTI uncomp; skin Infxns; anthrax; topical for bacterial conjunctivitis, community acquired pneumonia, chronic bronchitis. Dose: Usual 250750 mg/d PO or IV; Sinusitis 750 mg PO/IV 5 d; Prostatitis 500 mg PO/IV 28 d; Uncomp UTI female 250 mg PO/IV 3 d, if complicated 10 d; CAP 750 mg/d for 5 d; Anthrax acute 500 mg PO/d 60, start IV w/ other antibiotics; postexposure 500 mg PO daily 60; ophth12 gtt in eye(s) q2h while awake for 2 d, then q4h while awake for 5 d; in renal impair, avoid antacids if PO; oral sol 1 h before, 2 h after meals -Trimethoprim (TMP)Sulfamethoxazole (SMX) [Co-Trimoxazole] (Bactrim, Septra) [Antibiotic/Folate Antagonist] Uses: UTI Rx & prophylaxis, otitis media, sinusitis, bronchitis, diarrhea, Dose: Adults. 1 DS tab PO bid or 520 mg/kg/24 h (based on TMP) IV in 34 doses. P. jiroveci: 1520 mg/kg/d IV or PO (TMP) in 4 doses. Nocardia: 1015 mg/kg/d IV or PO (TMP) in 4 doses. UTI prophylaxis: 1 PO daily. Peds. 810 mg/kg/24 h (TMP) PO into 2 doses or 34 doses IV; do not use in newborns; maintain hydration -Metronidazole (Flagyl, MetroGel) [Antibacterial, Antiprotozoals] Uses: Bone/joint, endocarditis, intra-abd, meningitis, & skin Infxns; amebiasis; trichomoniasis; bacterial vaginosis; PID; giardiasis; pseudomembranous colitis (C. difficile) Dose: Adults. Anaerobic Infxns: 500 mg IV q68h. Amebic dysentery: 750 mg/d PO for 510 d. Trichomoniasis: 250 mg PO tid for 7 d or 2 g PO 1. C. difficile 500 mg PO or IV q8h for 710 d (PO preferred; IV only if pt NPO). Vaginosis: 1 applicatorful intravag bid or 500 mg PO bid for 7 d. Acne rosacea/skin: Apply bid. Peds. 30 mg/ kg PO/IV/d divided q6H, 4 g/d max. Amebic dysentery: 3550 mg/kg/24 h PO in 3 doses for 510 d;, Rx 710 d for C. difficile; decrease in hepatic impair -Penicillin V (Pen-Vee K, Veetids, Others) [Antibiotic/Penicillin] Uses: Susceptible streptococci Infxns (group A), otitis media, URIs, skin/soft tissue, Infxns (PCN-sensitive staph) Dose: Adults: 250500 mg PO q6h, q8h, q12h. Peds. 2550 mg/kg/25h PO in 4 doses; in renal impair; on empty stomach - Vancomycin (Vancocin, Vancoled) [Antibiotic/Glycopeptide] Uses: Serious MRSA Infxns; enterococcal Infxns; PO Rx of C. difficilepseudomembranous colitis

Dose: Adults. 1 g IV q12h; or 15 mg/kg/dose for colitis 125500 mg PO q6h.