Ce eeCee as Hyp [ewieas) — th-&, raorno, 20S Aleshet Per Ether Give al Ap? “containing ~ OH. -0H —}R-€H}-O + — Eye Ob ee an — R yr Peatlady palenasy (H,~OH Za 2 bentlic a ap (ontalning ~OH eh eal €=€—OH Vinyl aS E] Common names) LN GlelclbiG Ue ye deere erry a la Ne bb jb |b[ nacre: 206 | Reh 0774 | ida! ae , ct at | *y yy » s Fad alKeney — US By acld=Aetin hydlalin of al eney a 5; ay : Chet tii peo Hp Crh CH Cis “ OH me * allterey wuith wialeh Ja acidic rredjn 2 addi accaiding $9 moskovnikov Avle a ‘ a Mechan tor ra IZ H® + 0 3 tho® S me" war a 7 a 6st 4 eo —> <2 et — @. ye S : prolinabion oh oltre ho give tashocin infrreliae ie eh = ~ ee SS . ; - a O-H = = if i rt nudeaphib addition of wales x = i ‘ 5 : : x 5 =40 21 o de pxolonattenPAGE NO. 10}. | pare: 914 104 Ly we want po add wat to afkewe pe need alihol ao Lawits acdi2len 12> Oxy meycuiahin~ demercvhatda fe we _wont |b a(carding 9 markovnikov Avle_withovt pera Srgnaill Ch= cH Ch (Hh=CH=(H, Helm). Shy sO OAC oe ou (ty= (H=CHy C= Cb 1 thy - Oxidatdn b 1 aleren On NeOctidn with Ahan sivas ful=alkel—bdian whlch dn heart With hydiss en pudside In alkali median give, aliohst, ite fhadit of Atectitn la appasie la hak ppoduel by rreandvaltov VP UEH ELLE OOOGUGYeee re eVyVYY Ye se dcef yp - ce 74/207] AN lee (tye (He (H ss a pac Bate (ho thse tik Sn cis een ae = aM Hy (HEC, Pa oy Lergttye 8 yas (t= eth nd ca oe TL TT nd (3 (CH 08) = ———— xe =a Ub From alkyl hollde ad Wky| hal)dey dn A@acHin With agus aol On Kon udey® ||__nvelgophille pubsib Hin b9 give alco: . an = | ay KOH, on on = 5 a4, NaOH u ~ = Sh Engea (aban, Cerposede = Rebey _dn (Akola hrydadsPnatiin wh Aeducttn S 5 LiAtly on ADM aivea fhimaly aleohol ot peededeay adh ALopertively oe . ? Wabity Re OHsal! formaldehyde — i aldehyden —? Robina Bs -}6 >< Cosbongic acide ost fiat candela CA, hin dn clo hydaognation giver alcohol Attromh , fur convener of camborgh atid f aliohd , te fees of oubonuli gerd uith diblie Ly pusfjued becovat Ie will ly tedve Cosbortc acid ho alcahd_b ddepnt affect ok hear A feel oot like nitad, holo ok 2S Fada gAlgnosd heaget Ses Rmx \ KR oe NweeR 7 = ommex 7 70H Py cag Rito te mo, Wy OR H7_omgx U7 >on Oe Lee ee + vad en aa G H wit Y *Ohigy. Hose op oral g Peay RV pag Beat le tho ws SUELO REECE OCUUEELYYOYYYY ere reede gi% Now6K, 300m —~~ = ~tan fiom bertéreptphanle_ acl a SO, _ONa Ou = HyS0y . A Nao hot AN pe? QD 9 G6 oe a Gs o-— wel Dh) ‘ e 3} rom dlananioma alt a Nt” ou ea A FB Ss unio ss Zs 4 UP hore comers a < ume hydopronide 1earHan sy t af cy ~ : Q (y=(H=CHy Cyc 0OF ow " Ay tihtinthly Ne A 09, AY ‘ SA ara ALL” bp aim SAL Sa ees “tts AN, Benzene Tey + AHO Say Cth- CHLe - [oie ao | le [=e raaeno: 2 pares 14 10y Phopicad proputie) both ase poleble In waka dve to H=bduding with watea. Howards, Adtvblliy decdtasty Ww With Invlag jn _gite aie auburn chain de be incooe Dn hydophoble intact) | es © al@hly have_hi. iin point than hyd ¢ Compasa rnd |_rnaspeo gine aliahsl paopry ineimsloculad f-bdnding ' Pyestaan < ery < alley hallde < ketore < aldegde xa PTT ea > eter > amidea > aloha > _nitviler > anne Ea - foe ical. padpesties ee er a Nucles pide ClecHoprlle 0 x al Ora bias “yale fo eJgiallowe TR + HO RO + OHO Alalte oe Lanpbda ig fey behave lite Uap b nucleophlle Cepending dr HA fype of cleavag Reacting Bestia Ineliey —Jeavags of OH ban) [Ht Reactlin with retely Alchole On seoctisn with active poofale Ten ic K, Mie by 9a6 ee 0 16 0 10 16 16 6/6 )0/ 0/0) ©) ele & pia AER teh ene iurt Kosala a pp : y | Alcohol dd pot pear with aqueous alReli pd phendle oat a Rall becavot ft Ip md artdle Dp | (e) a (y= + Tt 3 ago La +h } 7 4 24 — 3 ReoH Nay Rona? + hb a > > > S : Te OH bind In aloha! in highly pola due fo laiyt difjereme Ia Wethlinenattiny \behuon Oy fb Hi. Thatly why Bloshels oho ca addic ‘ S, = = ; eS es ‘i Pe r (Wyien jo deesoer polniiy of OH bord. Meno, dearest br-acidh PPL chavs d 7 F Alcahalo ay [ep acidic tran walen oD alfanide accego pido fran BO Ro®+ 4,0 = tone Oe < On fh tale (B01? 1 may addk than wale) A Phen i Fc abcd Dike_e/hom s Cats Ol to" + HO ion > te ay f ; a is fzt . TAGE NO. os. ) Sy. (omg, ae te | Ayla d disactatin of OF ban pol hte Ta dee bs Mg dnunt That wh’ in cco hol, Penal han dectidn = =~ wittadiawing pole whhh allduip OH bord bo bleak i) ho _e)ecti on Bie LoeG ee er 6 Lee, Saf #2 cial - I —T 8 PE ER phexne of eecran ulthblowhy a10p behease peteutrs of OH bod Hnvy Incatosha He acidic atl 2b Label lati ‘ > Alcohdla dy glenda de Azautin with coubanyl acid dr add elle o act anhadilde giv “kh. 9 6 ne thio renctibn ws! couborulic acld fakip place in He plosgne +t few diaoe of fontontiale) Zap om Mechanlon " Om a e : Peal Sk R0-t-e HO On it folie [3 city ele A WoO Which hoo ho be Atmel a Haul ays neo ag fuk place, Hb HULK UG OOOO yd ye PY Uy YY eeza i Ran aks 3 as Hume aage Kolbe» heattin 22 galleulk acid bana hol. Ag on hurr ur 2alicg fh acd ko eh abhudilde Ae_heach Raswae, Kure anpiitn. tml) ayaa as os =~ On ‘HERA a oe d=cny ~ olen, ate a eye x = ~e —rhy, x authy bai salloglh acl: fonpiti 7 preppy pp ip# Reactions invohirg cleavage of C20 bled _____ LS luca! 2 ‘lon Lucas Leaghat Ip a rmiyhue afb HLA De fe bos of this Hot be fie alhob a Qvble In water due bo Aatvatidn of H- banding wih tales Lut alte alice OX thle be fey {01m babidity in Saleh i: lisa ledate cli nae Hs Chace OW HA Wey C= i (i a P= pote ae oie S=10 huis Gh Cu-oh + Ha > ee LT dont prow Iuahiditg at hago Wmpesctig unk A Piivory alcohols geoct wath acai SA (dome wast with HE wx HOt) ur ; (+h (CH, OH SRP LLL ELEC OC Uy ye Yee r yy yy rere ceMUO, Abeehps on Abatiange tdlitb. ye 7 peal AE Lt Deby hatin alcohol _dn Heating wh polar fldhe acid puch wy 1450s Ha fdy urdergaen dchydaabn bd ge ei hore a <4 a Sirailon_clahydrabian (on_alay_ lake place tn plecwe of debydittny 9) ~ a =, He SOy , 143K ee ~ CNG ee? er ty fOu 8S A reich rro be 44016 2 (Hy Cos + Hs fOr, 20+ + CeO en” (th C=, aud Mesjanond i=l |= fhatonatton of aloha —" ‘ in Gini On,_ ttt" —> (isl =-O-n _{1- Removal af 9A Na | Ade no arora -. Wise: (ene /24 . me 3 Pepratooahan R i . 7 dg — 8S ee ee De De ss 27 xidatien e—_§| aliohdlo On Oxidatar with ab A (ike Kad.) gives Rs —{c t > ith alec ihe PCC ox dehidioginatin with ( L699 Fy) gitee aldara | Gy 99K ar a EE = = hs (Hs 7 Chota Ot tS ee > i S| . (Ha, oe ’ Cy 59K Pi ee . | a - (sy — . i mo | eandony olsholy yuan 3h Pg we) . OHldation Bi tS ice gl La lh a | a3° unaigo ahi gadien j | HO = OA = a R= Ch,- OH = 2 of i : ee s ee Ms & Saeesilataes coe f fea eee 620 W ee bet ee Qo iN A Rolly sales onidiee allele ateholy | itPeerys e2pperrery, 7 » 2» (Hs === (HE CH= CH= = GH 7S J — EN Jag | ot a je a , S i CHa —CH—- tH; CH S-€H—€— tH, £=)_8 ., Vy) u “SS . 0 ° ~S " a AlaKlen with be _HND sp : Yat Victon Meyen tert . om . uatd bo arr /dltrquich beluepn |", 2° 3° alcohols SS q 5 wi lodig, 4stloved by yeaction wi nittows arid (HNO) 25 ble Ba i i 100 ID. 2 alot) dike NoOk Hs > { t#I BA mea ames 4 124 Cely(t,0H4 Red Py Colatt L Aarlry Ci5(H, NOx Hey iheCA | Di NO. " Blood ded tts CH Ty ees E 4 (u,(n-on Rell, Cyc Moi, (thy sti— Ne 22 chs WaOtt + Blud #—— Ci, -C- 9, u C+ Libumann nitaszo deacon Prencly dn 22actiin wlth nitiowo acd: (HNe).giveo pean nitisas plensl which falter Leacly with dee mi molecule of plenst HO ghe pdopleet twhith dn Acacin with alal? gi_a pl] coloued Mndo ~prenslale dn. OH- -¢" Nat ott oh 4 A @ a Hinds o i, ‘Naow : : ee ea al Wr nf ‘ Ww oo a Q blve edad PP PPE SOG eG eee e eer yey yy 6Bene bade with Fell pha Vide ated iangh = on = re : : 6 By Fett ——> Hs] felOGHs)] + 3H te od =, violek compa _ =.% Ft finacol = Pinacaldre Aeauery erent ~ P —x * nie sot - Rae & > Ro C= Ooh ~ ) ’ u a OF OF l x { Pla cof Plog store = a Mechanlam - rang mB Rodi te oS a i ca sg Ss ee : % 7 t st i = 1 OW Sor 2H 4 = a EE minalian ~ Ry Ry Ryne OR eR ow 1 0 Tee a ' aa > lista > Chet 2 = s ents ~ ~ ~ ~ — &. d R, “oH = i = r 2 s x < Ss 3Ee oe Ne 2 “i [nome Sees (ome (44094 ce a ee Se | eee Lertoryele. Nowy ahh iuqactatienieg eee Dae - \ ritmo - am (4, iS O y cacy i pod: Ze Ne too ~ CHCl y Cat gba rl Dp . S by ua of altel! an hellhydin, ar H-O. a i i eal R oO Fe pion, aaa? ged = > genie ta i 5 B emel_seauttna ° DS foe ak, - a ica H * ? 7. ee ; ay oF ie Hy= C= oH oa S i === is + iy = CH=CH ; UC Co ~ s a “t : oH.0.2% Pron aolvtin Io anMcepte py ppp 4 1% frenot galutia, bo diving echaar In aGdle mediom, He attack of nucleyphl dcund an mealk pubstivied corbin wieigay In _bayle rediven He atta CIR of || nucleophile <9cwAs_r_Leop Aurgtitid (orbda p | PPERPPI HH fee a phenotlo) + Reduction OW 7. ) lew Ww Tt Oaldaviy plensl an Aten Ing fan L0nq Hy Idab dark (olovred bend quindre is” Pipipiplelpel PLE ALL LA Sirilon pepult 039 blalree! oH 6 NarCh.0> QD den pling! seach wlth 9 > __conidiving_agint Ben2oqulnone Penal ta datha. pon dintding be aciatng Jn nai deckidphUlk gubsbibvtity Maclin ord dunt reed lewle orld as\ ] eee ee o* raainon 223 | ya “t= Nitnatidn : a “9 2 " e | id. HINOS = oO Sy (=) No, o O- nltagihens p= wltndphenst oy st inhaled H-bird f we Ov NO} 2 Edntenttatet HVOs | NO2 pleats add The _rnizhue of O- nltagplendl h p- nitagplenet Jo zepuiled. by lear dighlllation botcowt he fvinds hop Inhlgmdloculy H-bond whieh Lowes Mo by at k_makwo )t pltarn vufadte wlerad p-nitiopknat havt_inltimpleolay p-bérding hich agents Ito baling Alot — Fon ied of plese. achd, plenesl ty [last tread with fuming Hy Sst Kolbe’ (thal dr teattdn with NaQl givto pleroxbe wich bo pnbie Aeotve Faas SR UGE EOE CUCU EY EY Yh YY grin howirds Uectiophilk duyHrutln 4 jeaclo with weak efetiolle Nhe (Or7 a, o~ e | raat 0, WwW | | bare, Wainy | GAlh9 —hydtory benealdthy de, which te aloo Ne CHO _||Rnovn_agaalicyloldery® UN ffm Tiemann “9 Na apt © Nut Eas chet ds ay, bah, er Ho ate, Cr risa ie pHnot , da Leach with ‘Monofuin jn ith TE Pretna of Nel or KOH gives a a PEERERI? » 2 a7Prf iv NNaoH ot — TS a) ‘a RGte iC Gr. L ene PeLLLED| ‘matno: 22S ) is met) 9127 | | 1 CO. NaH 5 (Hy (00 Na + (0, +h, 0 ONa ull oH | oH . “s he, | A Natica j a Nall, ==! pO -keactim —— LO + Hy [Noy NNO» ou oe Nats fon Natio, Bibk Yuva RE Bel ormmenciak Longdttanct of, alcorslo f Methanet Methanet * “ala beter a2 wad opie” $2 OS “fled by dete ae of ogod_——— * pidadayp, Th fy fddusl with cholate hydioseratitn of CO at 200-300 _ otra, $= 694K, in he filaind of Zn0-Cadg * €0 L eer aay Cte SG * (lowly : | * paleandvy * gral) quintihy (in (aver blindpea hil Hist quate dead by dap * Ueed dy solvent b f0A making “Heo Se 10 10 10 6 UGE UU Ee ed & ee YY aa: Inkermaleruley dahydatin —) CMA | % Intlamaleedor Lehydaatn—9 AL ROre yyy) __ 27 £Hhaneh eres - a + pdoduied by (Mmenttin of ag %_fyhdon rnelaono , gate tle 2 4uimentatian alad doe in youl by 25mg bpp | i Gta OS iH Ort G02 tora frvetoae: = lien 2 | 2GbsoH + 200, = * fiimnbation aewdd aneeishiably (ag in tH Get of wht rakhp) 9 ‘ = _# S Tyree Taklacky tala , — laf UW 2 Hf alcohol cdlent te leo than 4% daly Hen 2gmecr wil at WY qd ° a S| = 3 | vee . Ss = 'S Ie 5 | = So , a, | 2 1\, ‘ Na etic, lon expaced ho alr fan Long Hime gh poenide —— C / y pace no: 279. Which Io CLplOiR in nate (omer 14 | See +4 ¢ —— nA Os S gy fais Ae Res - Symmetsce Unogmerethicod 0. i= is ety Cg at — EHH Geena angle ly max In eter than lefvabed sal anole becavet Uf Jepulain bebvey 2% blhg Gliest Cthalny, chery have low pital, Hrxtor have Low boiling fot alee ad blbirs Jn valet, Tk bsiliog pol of eltty Jedvee with ino lca ~chainongth due £9 _hyduaphahic Lepuldino pt I Ag pos : : Pap aa: oe” # gi [ar By Inkesmnalecun debscatin ee , aiken . HAS Eos 413K a sie SPO G GLEE UE UU EY eee YU i i owe w amo 298 a partis 14 194 | f a Methankae a @ CCH, - 9-4 > Cth Cth oo ~ 2 D> Cre OL + eH G5 tH =f Ohl a oN hi 7 —' Q4 eth Cyt O- Uae Bs te Hy ge nin i = a wy Ue Neavhion fallown Sv2rsechanlon, Henfor aire daly {2% hay ~ —____laloddls, Te dahyduation of acinoty k tertiaay ahve abtoreo ‘ ee ag eg - Li Williaman dyntrepio eC eu irre ta al dies al [byl helldty do soachin ah olReaider ondeiges mucephil 5 Ldubshitvtion acho bo aive eHeho 5 5 Ss Bellen semulro of Willian ehel—syhitey'e ae adbled if alkyl | svide fa_pilmnang < Dn (oot of 2° ay 3° alkyl alte, dimpatin 5 * alk. all > ntvisn, a Ne aly Macklin pod bind ee) Jo abkaled, browse altos 5 aX nok oly nudophil ghliny baaey Oo well :| PAGE NO. 229 lewis 22 (Hy Oy [eig=e= Bn + CAO Na* —> CH, C= cH, + CHO + te 1 (bla, ONa OR Oo +R te bee Clerical Lag Heyy | Spa che axe Mtert beactive functional quo becauot el Aeachiyn Of Harp Avie clowege of (~O bird ubih Keke plag daly diaahe (dadjhions gush 0: phenence “of hdd ali acid ’ 1 One po 7 Gi Os Reockivity dad —7 HT > Ha? HU © (PO 8 PEE El Ve eee ered so OO & hr alae a @ mwvt Te. ee. ies HL Abn 2tcess AN pated . Hie Uonvk sere, Mth HL Ae porn Alkyl Lodede raon no, 2.90 (ons gs | II (t= o- CPU FOE CD mp Cr (HOH : WE follow SN, mechaniom v Si ballde aHacks deat Window (Hy Dt (Hy (D+ (aah . : i ppp hy / ' | | | | | a M a a == NOfretenatin one 7 2 ee Cty O Clery ee ay ci = —__|O.Medeaphiti_athouk + a Chlty 5 CH LH,O ~ 5 S ye at fie abkiol choing ty Hettlaty gna Nodly oeble > (arbgcabitn Yi hot_{uined, Hen He halldy aback 1 push on vl Imag oleble cuubscebivn can be_faAinerd_. oy +s " (ha CHC ae ett B= Cty HP = = re — ” CSE 9th PCy C gf == ! 1 = Bess Se ae fit?| @ on tha es ots |fHeny axe slightly leosin bare ince Hey Corals (Bot eibo whuh Hog (gn_dénak , tT Clatiaphillc aubatintin cf oudmatc_eltthe jeHass ax highly atively ke ddan foe dissing 19 tledophn adohidin z - g =l> = SJ= es Sz = z 3 3 = Z Avo eS =| At & sl= oly OH Ul A GY oan Sa oe ia oe ae ee (onasan) - BiOminaHty —Ehtoninatt 13) Flledel: Ciolt alhylabion Oy OM, oy ORs J ef aes RG Ye (reajas) (rmasan) NiMAHDA tae = Fated trey tegtation PP PP SEPP Syyvyegeseerrrrrrrrreweces & ”palldannaondh 4yninids phirriry atkye halide © acai anhycration 0 ateohot oR - On 790°C @ tataryiie dshydKation %F “ ° Aba 08 of 615 —O- HS 2 tq ns0H ; w40- 460% 2s ONE ST po R + H20 D action og aikiun oxide OM Alkyt R-X z ROR + 4gx + 4B20 a—x © addition oy Acohol ee QML Cts— Hg Cats —H — Hasog + 20 am Un a ota HsSoi ea _Aeachiin Falco. Ae amMange ment ~~ 18.) oy miss 1 9g } > | ° I | OW © Sout peti .) | anryd ALCS Zi -)) | O89. 6 aet-t main rar 2 imigid aye SOK “yt | PRREERUVELLLEEA cor cub Pe Pais PPP } : bpusin ened it bit Lust bade ? Yes 15. wT 5 (2 (9 [Se FLA LAL AA on fo yen z 5 acidic vache Wr ae buit bau . Mow C- atom 4 mon gedee un 3¢ Molecule nuhith dose Wot cuidine Mung. PCE C1 PS om Arm (20 / on cn ey, n e rT pond avenge HS OKT