National Immunization Schedule (NIS) of India:
Detailed Table
This schedule is based on the Universal Immunization Programme (UIP) guidelines.
Vaccine When to Give Dose (Volume) Route Maximum Age Common Side
for Catch-Up Effects
BCG (against At Birth 0.1mL (0.05 mL Intradermal 1 year Localized
Tuberculosis) until 1 month) (ID) - Left swelling,
Upper Arm ulceration, and
permanent
scar.
Hepatitis B At Birth (within 0.5 mL Intramuscular 24 hours Mild
(Birth Dose) 24 hours) (IM) - Thigh pain/soreness
at the injection
site.
OPV-0 (Oral At Birth 2 drops Oral 15 days None specific.
Polio Vaccine)
Pentavalent 1, 6 weeks, 10 0.5 mL Intramuscular 1 year Fever, pain,
2, 3 (DPT + weeks, 14 (IM) - Thigh swelling, and
Hep B + Hib) weeks redness at the
injection site;
irritability.
fIPV 1, 2 6 weeks, 14 0.1mL Intradermal 1 year Mild redness or
(Fractional weeks (ID) - Right swelling at the
Inactivated Upper Arm injection site.
Polio Vaccine)
Rotavirus 6 weeks, 10 5 drops Oral 1 year Mild fever,
Vaccine (RVV) weeks, 14 vomiting, or
1, 2, 3 weeks diarrhea.
PCV 1, 2 6 weeks, 14 0.5mL Intramuscular 1 year Fever and local
(Pneumococcal weeks (IM) - Thigh swelling/pain.
Conjugate
Vaccine)
MR-1 9–12 months 0.5mL Subcutaneous 5 years Low-grade
(Measles-Rubel (SC) - Right fever, mild rash
la) Upper Arm (7-10 days after
vaccine).
PCV Booster 9 months 0.5 mL Intramuscular 1 year Fever and local
(IM) - Thigh swelling/pain.
Vitamin A (1st 9 months (with 1 mL(1 lakh IU) Oral 5 years (for all None specific.
Dose) MR-1) 9 doses)
DPT Booster-1 16–24 months 0.5 mL Intramuscular 7 years Higher chance
(Diphtheria, (IM) - Thigh of fever, pain,
Pertussis, and swelling at
Tetanus) the injection
site.
Vaccine When to Give Dose (Volume) Route Maximum Age Common Side
for Catch-Up Effects
MR-2 16–24 months 0.5mL Subcutaneous 5 years Low-grade
(Measles-Rubel (SC) - Right fever, mild rash
la) Upper Arm (7-10 days after
vaccine).
OPV Booster 16–24 months 2 drops Oral 5 years None specific.
DPT Booster-2 5–6 years 0.5 mL Intramuscular 7 years Mild soreness
(IM) - Upper at the injection
Arm site.
Td (Tetanus & 10 years and 0.5 mL Intramuscular Adolescence Pain and
adult 16 years (IM) - Upper (as per swelling at the
Diphtheria) Arm schedule) injection site.
For Pregnant Women
Vaccine When to Give Dose (Volume) Route Common Side
Effects
Td - 1 (Tetanus & Early in pregnancy 0.5 mL Intramuscular Pain and swelling
adult Diphtheria) (IM) - Upper Arm at the injection
site.
Td - 2 4 weeks after Td-1 0.5 mL Intramuscular Pain and swelling
(IM) - Upper Arm at the injection
site.
