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Culture Documents
Immunization Programme)
Schedule in our state
If received 2 TT
doses in a
TT - Booster 0.5 ml Intra muscular Upper arm
pregnancy within
the last 3 yrs
At birth or as early
HBV Anterolateral side
as possible with in 0.5 ml Intra muscular
Birth dose of mid thigh
24 hrs
At birth or as early
OPV - 0 as possible with in 2 drops Oral
first 15 days
0.05 ml till 1
At birth or as early month
BCG as possible till 1 Intra dermal Left upper arm
year of age 0.1 ml after 1
month
BCG is not given beyond one year of age and there is no need to re-vaccinate the child
even if no scar is formed.
IMMUNIZATION SCHEDULE FOR INFANT
Vaccine When to give Dose Route Site
9 completed months
Measles to 12 months
0.5 ml Sub-cutaneous Right upper arm
1st dose
Can give up to 5 Y of age
9 completed months
JE 1 0.5 ml Sub-cutaneous Left upper arm
to 12 months
Vitamin A 1 ml
9 months Oral
(1st dose) (1 lakh I.U)
IMMUNIZATION SCHEDULE FOR CHILD
Vaccine When to give Dose Route Site
Measles
16-24 months 0.5 ml Sub cutaneous Right upper arm
2nd dose
At 16 months
with DPT/OPV/JE/
Vitamin A Measles 2 ml
Oral
(2nd to 9th dose) (2 lakh I.U)
And then, one dose every
6 months upto 5 Y age
IPV Intradermal
(right upper arm)
Sequence of vaccination at 6 & 14 weeks
1 2 3 4
4
3
BCG Vaccine
Bacillus Calmette Guerin
Live attenuated vaccine
Copenhagen (Danish 1331) strain is
used to produce vaccine
Lyophilized (freeze-dried) preparation.
Contains 0.1-0.4 million live viable
bacilli per dose.
Extremely heat and light sensitive.
BCG Vaccine
Diluent is sterile normal saline.
Reconstituted vaccine should be stored at
2 to 8°C, protected from light and discarded within
4 to 6 hours of reconstitution.
As the vaccine contains no preservative, bacterial
contamination and consequent toxic shock syndrome
may occur if kept for long after reconstitution.
Efficacy: 50-80% for prevention of miliary and
meningeal TB. 50% for pulmonary tuberculosis.
Contraindications: Cellular immunodeficiency,
symptomatic HIV
BCG Vaccine
Dose: 0.05 ml to < 1month. 0.1 ml for older
children.
Route: Intradermal with 26G needle
Site: The convex aspect of the left shoulder at
level of deltoid insertion
Method: The selected site may be swabbed
clean using sterile saline and local antiseptics
should be avoided. A wheal of 5 mm at the
injection site indicates successful intradermal
administration
BCG Vaccine
2-3 weeks: Papule develops
5-6 weeks: Papule increases in size to 4-8 mm
6-12 weeks: Heals with ulceration and scar
Oral Polio Vaccine
Contraindications: Immunodeficienct children, house
hold contacts of immunodeficient patients. Leukemia &
other malignancies. Severe diarrhea and dysentery.
Adverse Reactions:
o VAPP (Vaccine Associated Paralytic Polio) – due to
Serotype 2.
o cVDPV (Circulating Vaccine Derived Poliovirus) –
Paralytic Polio cause by virulent strain formed due to
mutation of OPV.
Inactivated Polio Vaccine
Formaldehyde killed vaccine.
Induces humoral immune response.
Doesn’t not induce mucosal immunity & doesn’t have
herd effect.
Potency is measured by D antigen content.
Each dose is 0.1 ml.
Storage: At 2-8O C
Route: Intradermal
Has the advantage of not causing VAPP (Vaccine
Associated Paralytic Polio)
Inactivated Polio Vaccine
Fractional immunization:
o IPV 1st and 2nd doses are given at 6 wk & 14 wk
respectively under UIP.
o Intradermal in Right upper arm.
Measles Vaccine
Live attenuated vaccine
Edmonston Zagreb strain
Freeze dried form, no preservative.
Dose: 0.5 ml
Route: Subcutaneous
Site: Right upper arm (at insertion of deltoid) or
Anterolateral thigh.
Measles Vaccine
Schedule: At 9 months. 2nd dose at 16-24 months.
Contraindications: Immunodeficiency, On
immunosuppressive therapy, Malignancy
Adverse reactions: Fever, transient macular rash
(Measles like Illness) 5-10 days later.
Hepatitis-B Vaccine
Viral subunit vaccine (Surface antigen)
Adjuvant Aluminum Salts, Preservative Thiomersal.
Dose: 0.5 ml (1 ml contains 20 µg of antigenic
component)
Route: Intramuscular
Site: Deltoid or Anterolateral thigh. Avoid Gluteal.
Schedule: At birth. At 6 weeks, 10 weeks & 14 weeks as
a part of Pentavalent vaccine.
95% seroconversion (Antibody titer >10 mIU/ml) after 3
doses.
Adverse reactions: Mild erythema, induration at
injection site, fever.
Pentavalent Vaccine
Protection to a child from 5 life-threatening
diseases – Diphtheria, Pertussis, Tetanus,
Hepatitis B and Haemophilus influenza
Type B.
Dose: 0.5 ml (Each vial 10 doses)
Route: Intramuscular
Site: Deltoid or Anterolateral side of mid-
thigh.
Schedule: At 6 wk, 10 wk & 14 wk