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SRI LALITHAMBIGAI MEDICAL COLLEGEAND

HOSPITAL
Faculty of Medicine, Dr.M.G.R.Educational and Research Institute
ADAYALAMPATTU, MADURAVOYAL SERVICE ROAD, CHENNAI-600095.
Phone No: 044-2957 1111 / 2222, 9790777364

DEPARTMENT OF COMMUNITY MEDICINE

MUSEUM CATALOGUE

VACCINES

Department of Community Medicine

Sri Lalithambigai Medical College & Hospital
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VACCINES

PAGE
SL.NO TOPICS NUMBER

1. DPT vaccine 3

2. TT vaccine 4

3. Hepatitis- B vaccine 5

4. Measles vaccine 6

5. BCG Vaccine 7

6. Oral polio vaccine 8

7. Typhoid vaccine 9

8. PENTAVALENT Vaccine (DPT, HiB, Hep B) 10

9. QUADRIVALENT Vaccine (DPT, HiB) 11

10. JE Vaccine 12

11. Pneumococcal Vaccine 13

FRACTIONAL INJECTABLE POLIO

12. 14
VACCINE (fIPV)

13. Rabies vaccine 15

14. Auto disabled syringe 16

15. Vaccine vial monitor 17

Department of Community Medicine

Sri Lalithambigai Medical College & Hospital
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DPT VACCINE

Type of vaccine: Triple vaccine / Combined

Composition :  0.5 ml have diphtheria toxoid 20 Lf, tetanus toxoid

0.5 Lf , Pertussis killed -20,000
million,
 Adjuvant- aluminium phosphate-
2.5 mg,
 Preservative - Thiomersal – 0.01%

Route of administration:
Deep IM
Dose: 0.5 ml
Site: Outer mid-thigh (infants), outer upper arm (old child)

Schedule :
 1st dose – 6 wks
 2nd dose – 10 wks
 3rd dose – 14 wks
 Booster doses at one and a half yr and 5 yrs.

Efficacy: For diphtheria and tetanus 95-99% but for pertussis 70 – 90 %

Contraindications :  Acute illness,

 Anaphylactic reaction to the previous dose,
 Neurological disease

Adverse reaction: Fever rarely convulsions, redness, pain & induration at the site of inj.

Storage: 2 to 8o C

Availability: 10 ml vial

Department of Community Medicine

Sri Lalithambigai Medical College & Hospital
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TETANUS TOXOID (TT) VACCINE

Type of vaccine : Toxoid Monovalent

Route of administration: IM

Dose: 0.5 ml

Site: outer upper arm

Schedule: 2 doses of TT given in the 10th and 16th years

Pregnancy: First pregnancy: 2 doses at 16 weeks and then after 4 weeks

Second pregnancy: 1 booster dose in, if within 3 years

Efficacy: 99% over 5 years

Contraindications :  Acute and serious illness,

 Anaphylactic reaction to the previous dose

Adverse reaction: Fever, Urticaria

Storage: 2 to 8o C

Availability: 5 ml or 10 ml vials/1 ml ampoule.

Department of Community Medicine

Sri Lalithambigai Medical College & Hospital
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HEPATITIS- B VACCINE

Type of vaccine: Plasma-derived vaccine

Composition: 20 micrograms of HBs Ag/ ml

Route of administration: IM

Dose: 0.5 ml for children, 1ml for more than 10 years

Site: outer mid-thigh / outer upper arm

Schedule:
 Zero dose: at birth
 1st dose – 6 wks
 2nd dose – 10 wks
 3rd dose – 14 wks

Efficacy: 95% over 5 years

Contraindications: Anaphylactic reaction to the previous dose

Adverse reaction: fever, local redness

Storage: 2 to 8o C

Availability: cloudy liquid in single/multi-dose vials

Department of Community Medicine

Sri Lalithambigai Medical College & Hospital
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MEASLES VACCINE

Type of vaccine: Live attenuated, freeze-dried

Route of administration: subcutaneous

Dose: 0.5 ml

Site: outer mid-thigh / upper arm

Schedule :
 1st dose – 9 months along with Vitamin A supplementation
 Booster dose – 16 to 24 months

Efficacy: 95% almost lifelong

Contraindications :
 Pregnancy,
 Immune disorders,
 Anaphylactic reaction to the previous dose

Adverse reaction :
 Mild fever
 Rash
 Toxic Shock Syndrome
 Encephalitis

Storage: 2 to 8o C

Availability: Vial with powder and separate diluent (distilled water)

Department of Community Medicine

Sri Lalithambigai Medical College & Hospital
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BCG VACCINE

Type of vaccine: Live bacterial freeze-dried

Route of administration: Intradermal

Dose :
 0.05 ml for less
than 1 month,
 0.1 ml for more
than 1 month (up
to 1 year)

Site: Upper left arm just

above the insertion of
the deltoid

Schedule: At birth, if not given within or <12 month

Efficacy: 70-80% almost lifelong

Contraindications: pregnancy, immunodeficiency

Adverse reactions:

 Ulceration

 Lymphadenitis

 abscess

Storage: 2 to 8o C

Availability: freeze-dried powder along with diluents (normal saline)

Department of Community Medicine

Sri Lalithambigai Medical College & Hospital
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OPV VACCINE

Type of vaccine: Live Bivalent Oral Polio vaccine

(Types 1 and 3)

Route of administration: Oral

Dose: 2 drops (each drop of 0.05 ml)

Schedule :

 0 dose - at birth,

 1st dose – 6 wks

 2nd dose – 10 wks

 3rd dose – 14 wks

 Booster dose 12-18 months with DPT

 5 years with DPT

Efficacy: 100% lifetime

Contraindications: immune disorders

Adverse reaction: Vaccine-associated paralytic

poliomyelitis (VAPP) - Rare

Storage: 2 to 8o C

Availability: 2 ml (20 doses) vial with dropper

Department of Community Medicine

Sri Lalithambigai Medical College & Hospital
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TYPHOID VACCINE

Type of vaccine: Vi polysaccharide type

Route of administration: IM

Dose: 0.5 ml more than 2 years,

Booster every 3 years

Site: outer mid-thigh

Schedule :
 1st dose – more than 2 years,
 Booster every 3 years

Efficacy: 75-100%

Contraindications :

 Acute illness,
 Immunodeficiency disorders,
 < 2 years

Adverse reaction: Rashes

Storage: 2 to 4o C
Availability: 10 or 5ml dose vial

Department of Community Medicine

Sri Lalithambigai Medical College & Hospital
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PENTAVALENT (DPT, HiB, Hep B) VACCINE

Type of vaccine: Pentavalent

Route of administration: deep IM

Dose: 0.5 ml

Site: Outer mid-thigh

Schedule :

 1st dose – 6 wks

 2nd dose – 10 wks

 3rd dose – 14 wks

Efficacy: 90 %

Contraindications :
 Acute illness

 Anaphylactic reaction

Adverse reaction: Fever, local inflammation

Storage: 2 to 8o C

Availability: 10 ml vial/ single dose pre-filled syringe

Department of Community Medicine

Sri Lalithambigai Medical College & Hospital
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QUADRIVALENT (DPT, HiB) VACCINE

The quadrivalent injection contains Diphtheria Toxoid, Haemophilus B Conjugate

Vaccine, Pertussis Toxoid, and Tetanus Toxoid as active ingredients.

Type of vaccine: Quadrivalent

Vaccine Route of administration: IM

Dose: 0.5 ml

Site: Outer mid-thigh

Schedule: 1st dose – 2 months to 6 years

Efficacy: 90 %

Contraindications: Acute illness

Adverse reaction: Local reactions at the site of injection

Storage: 2 to 8o C

Availability: 10 ml vial.

Department of Community Medicine

Sri Lalithambigai Medical College & Hospital
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JE VACCINE

Type of vaccine: Live Vaccine (SA 14-14-2 strain)

Route of administration: Subcutaneous

Dose: 0.5 ml

Site: Left upper arm

Schedule: single dose between 16 & 24

months of age (in a few States)

Efficacy: 98 – 99%

Contraindications: a person with fever or malnutrition, pregnancy,

allergy/convulsions etc.

Adverse reaction: transient fever, rash, irritability, local reaction- redness,

tenderness

Storage : +2 to + 8o C,

Reconstituted vial to be used within 2 hours of reconstitution.

Diluents are to be stored at +2 to + 8o C,

Department of Community Medicine

Sri Lalithambigai Medical College & Hospital
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PNEUMOCOCCAL VACCINE

Type of vaccine: Conjugate

ROA: IM or SC

Dose: 0.5 ml

Site: left upper arm or

lateral mid-thigh

Schedule : Children: ≤ 2

years & adults ≥ 65 years

Efficacy: 89%

Contraindications: Pregnancy,

allergy/convulsions

Adverse reaction: local reaction- redness,

Storage : +2 to + 8o C

Use: Prevents pneumonia (Streptococcus pneumoniae), meningitis & sepsis

Department of Community Medicine

Sri Lalithambigai Medical College & Hospital
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FRACTIONAL INJECTABLE POLIO VACCINE (fIPV)

Type of vaccine: Killed

Route of administration: ID

Dose: 0.1 ml

Site: left upper arm

Schedule: 6 weeks & 14 weeks

Efficacy: 80 – 90%

Contraindications: anaphylaxis,

streptomycin/ neomycin hypersensitivity

Adverse reaction: local reaction- redness, tenderness

Storage : +2 to + 8o C

Availability: 0.1 ml AD syringe

Department of Community Medicine

Sri Lalithambigai Medical College & Hospital
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RABIES VACCINE

Type of vaccine: Killed vaccine (cell cultured inactivated vaccine of purified chick

embryo cell vaccine) [PCECV type]

Route of administration: Intradermal or Intramuscular

Dose: 0.1 ml ID or 1 ml IM

Site: Upper arm

Schedule : Days 0, 3,7,14 &

28th day after exposure & a booster dose

on 90th day

Adverse reaction: headache, local reaction- redness, tenderness

Diluent: distilled water

Storage : +2 to + 8o C

Department of Community Medicine

Sri Lalithambigai Medical College & Hospital
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AUTO DISABLED SYRINGE

 Auto disable (AD) syringes are designed as a single-use syringe, with an internal
mechanism blocking the barrel once depressed so it cannot be depressed again.

 To protect healthcare workers & others from accidental needle stick injuries

 An internal mechanism cracks the syringe when the plunger is fully depressed to
prevent further use.

 These syringes are only effectively disabled with a full depression of the
plunger; users can avoid activating the re-use prevention feature and re-use
the syringe.

 The reuse of disposable Syringes and needles leads to the transmission of blood-
borne pathogens such as Hepatitis B, Hepatitis-C, HIV and other infections. Auto
disabled syringes provide a solution to the problem of unsafe injection practices
arising due to the use of reused syringes.

 Auto disposable Syringes are made of non-toxic, medical-grade

polypropylene compatible with all medicines

 1ml, 2ml, 2.5ml, 3ml, 5ml, 10ml and 20ml syringes are available.

Department of Community Medicine

Sri Lalithambigai Medical College & Hospital
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VACCINE VIAL MONITOR

 A vaccine vial monitor (VVM) is a label containing a heat-sensitive material placed on a
vaccine vial to register cumulative heat exposure over time.
 The combined effects of time and temperature cause the inner square of the VVM to darken,
gradually and irreversibly.
 A direct relationship exists between the rate of colour change and temperature:
 The lower the temperature, the slower the colour change.
 The higher the temperature, the faster the colour change.
 The VVM is a circle with a small square inside it. It can be printed on a product label,
attached to the cap of a vaccine vial or tube, or attached to the neck of an ampoule.
 The inner square of the VVM is made of heat-sensitive material that is light at the starting
point and becomes darker with exposure to heat.
 At the starting point, the inner square is a lighter colour than the outer circle. From then on,
until the temperature and/or duration of heat reaches a level known to degrade the vaccine
beyond acceptable limits, the inner square remains lighter than the outer circle.
 At the discard point, the inner square is the same colour as the outer circle. This reflects that
the vial has been exposed to an unacceptable level of heat and the vaccine degraded beyond
acceptable limits. The inner square will continue to darken with heat exposure until it is much
darker than the outer circle. Whenever the inner square matches or is darker than the outer
circle, the vial must be discarded.

Department of Community Medicine

Sri Lalithambigai Medical College & Hospital
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Department of Community Medicine

Sri Lalithambigai Medical College & Hospital
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Department of Community Medicine

Sri Lalithambigai Medical College & Hospital