URIC ACID ALLAN101N lC,H,MyO3] Struduue ot panabaniu acid
(uhen i c aic us oudiLd uth aqueous
TUPAC nam; Pusine-2,6,8in, 2%,3 n)-triona eanabanu Hz0 Us t yoxalu aud
acid
Guunno [bid excrement found un leutrn peo dcts e Obtaind in a quan
Stuctunal tormulo Coat y South amesçua]-25'|. wwic acid
-tatue utd ifoudation iscavid out uth
So'. Snakes excrernetAmmonium
acid, t us
HN, Hate quoupp e t un panabanù
Uine os uic acidScheel)
Ctound un nany caleul)
Na mca COon
CH,n,o +2n,0 Is sluctue haue bean cenysuma by
uacid usa mMatuel uaste pedutt
em he huakdown puwines that C0on
Condensation Oxalylchloude uth
paus thsuough
memally disaalus in bled, (meso oLaliq
wwine acid
Kidntys and exits through Structue Allanhinbaeyer
cause t houus than in aloan th Hes CUhen hyduo lyed uuth alkali,it tom -2nce
"High u l of Uea (hypenicemia) Uunl
tuo ua mauule and enemaleude y
and
paintul qout and kdney sters , no Ree amino OR guee cauboxe eup
Qou Quuts (uypotiemia) am signal
t u claHd, that
Euom the abaue Ract,
otheySUes HN
- 2N)0
C=0
Nnaantain certains panbanie acid muduu
ALLOXANC,M, N, Ou] H
4
Cho KK**
2n,0
Deduction Dectisn pount ag attactmsi
COon
eaual
quus alloan and wea in
Alloxrun mdmah_dunte uspupaud bom un stuuctune oallamtain !
Cumaunt
baubitui acid as follaus Rormation a thee uyduo uyte puoduct Auggst
HNO
(alloran) h t allartoin s dwwd yoxalucaaPaiaaHochront is deduck by expimert
Ch-Ph
Ph-cho al uidurcs uhn aeanto çsuduced
HN
PARA BANIc ACAD CH,N, O,] uith Con hyduaisdic acd (( nI) at LO0c
[o3 Oooidaben cuth tNO, ,alanton Ques
to gue hydanion and MLa
mount paabane aad and wa n egual
(Hydartain)
puopotien
Struchun oj Aloxan:
uhen hyduotysed. uth alkali ,alloxan (wun') (Allartain)
puoducs weo 4 mesooxa le acid
4
enual
AMonan manohyduat mount
C Ng Hg4 Plz0 (Pnabanic acid)
allantsin a Based on the stuctun abeue "Ebig gounula ull gue only one mono
HYDANT0IN (ne olauung stuucturu
usuld accaunt on ale the Ronegg -melhyl wie acud
haue been peoposd by scienat
Hy dantoin an cortuotld yduiyis giues uactisns
Medicus gomula satisty the existence
) Medcus femula (2) fittig foumula eomethy dericatue
Pydantai arid ( wudo acticacid) uhih (1878)
at dent 2- somi
Nuduw (05)
co,
an gwnhydusyesqus-glycne pavaban
dne methyl quoup at odho postion
will
psduce methyl alloxan and wa t
HN methylqeupin umidazole elus
H20
Hydanteun tydantaic
acid
coz (zoR gnpositun) uiel puedue alloxen
t
Bshe pupaved 2-menemothuyl Wic d
Ng lhydiuso and methylua
rgarlain Lbemns
H,0
(gdanlaiacia), Rauabanii acd
Mudscus ponule Sugqests that ths
> HOOC -Cn, Nn(-Nn, Uea possibilthy tomatien 4
On
(1) (T) 4- monomethyldevatíe
6- dinetul diutue
l2moleculs wea
mthye allonan Aloran 4- trimehyldeiuatie
Glyoxal acid
a methyt wua Sn)+ ny medicus fomuia s pjUd
Jhe auctune 04 allantoin ha been Queu tg tomua gor sutne o
HNCH-coon bic acid?
Cangumd ty syniheis wuhne 2
(gycine) moculis o Uua ae huatud ith IRAVBE'S SYNTHESIS of URIC AaD:
+ Co,+ Nn qlyoralie acid
(ayoxalic acid) HN
NaoH
en
Strudune rydarntin : CEN CEN
Stuclune q tyydantain is conguud by actin ho
(wua) (wua) (5,6-diamiinonacil ]
N0
NHy HS HNO
cny -2ner
H
(g dondain)
(allanlain)
S=o ic acid)
