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Step 1. Define the patients problem Step 2. Specify the therapeutic objective What do you want to achieve with the treatment Step 3. Verify the suitability of your P-treatment Check effectiveness and safety Step 4. Start treatment Step 5. Give information, instructions and warning Step 6. Monitor (and stop ?) treatment
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2. Specify the therapeutic objective 3. Make an inventory of effective groups 4. Choose a group according to criteria: Efficacy, Safety, Suitability, and Cost
Conclusion: Active substance, dosage form, Standard dosage schedule, Standard duration
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Suitability:
Contraindications. High risk factors / groups Drug interactions Are the active substance and dosage form suitable for this patient ? Is the standard dosage schedule suitable for this patient ? Is the standard duration of treatment suitable for this patient ?
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CHOOSE A GROUP ACCORDING TO CRITERIA efficacy safety suitability NITRAT (or) + + B BLOKER (inj) + CALCIUM CH.BL(inj) + CHOOSE A P DRUGS Glyceryl trinitrat (tablet) Spray Isosorbid dinirate (tabl) Isosorbid mono nitrat (tabl) efficacy safety + + + +
cost + -
Kesimpulan : senyawa aktif : glyceryl trinitrat, tablet 1 mg sublingual skedul dosis : 1 tabket apa bila dibutuhkan 2 tblet apabila nyeri masih ada lama pemakaian: sepanjang dilakukan monitoring 12