Professional Documents
Culture Documents
Overview
10
Three types
Primum ASD
Secundum ASD
Sinus venosus
AVSD Atrio ventricular septal
defect
11
Primum
Sinus Venosus
ASD- Anatomy/Prevalence
Secundum 75%
Primum 15%
Sinus Venosus 10%
Cor Sinus (rare)
13
14
Physiologic Consequences
Shunt Flow
Size of defect
Relative compliance of ventricles
Relative resistance of pulmonary/systemic circulation
1Perloff,
NEJM 1995
Clinical Symptoms
Physical Signs
S2 wide/fixed splitting
RV/PA palpable impulse (if lg defect)
systolic ejection murmur 2nd L ICS
mid-diastolic TV rumble
17
Auscultation in ASD
18
ECG
19
ECHO
Subcostal
view of
Intraatrial
Septum
Color Flow/
Contrast
Good for
secundum,
primum
20
Treatment
21
Treatment
Surgical Closure
Good prognosis:
22
24
Three types
25
26
May be anywhere in
intra-ventricular septumclinical course depends
on the shunt size and
involvement of
pulmonary vascular bed.
Approx of all VSDs are
small, and more than
close spontaneously.
Highest closure rates in the
first decade of life.
27
PATHOPHYSIOLOGY
CLINICAL FEATURES
29
PHYSICAL FINDINGS
30
INVESTIGATIONS
CHEST RADIOGRAPHY
- normal
- biventricular hypertrophy
- pulmonary plethora
ELECTROCARDIOGRAPHY
-smallVSD ~ normal tracing
-mod.VSD ~ broad,notched P wave characteristic of Lt. Atrial overload as
well as LV overload,namely,deep Q waves & tall
R waves in leads
V5 and V6 and often AF
-large VSD ~RVH with rt. axis deviation. With further progression
biventricular hypertrophy;P waves may be
notched/peaked.
31
INVESTIGATIONS .
ECHOCARDIOGRAPHY
two-dimensional &doppler colour flow
ANGIOGRAPHY
(cardiac catheterization and angiography)
32
COMPLICATIONS
INTERVENTION
3 MAJOR TYPES
SMALL (less than 3mm
diameter)
- hemodynamically
insignificant
- b/w 80-85% of all VSDs
- all close spontaneously
* 50% by 2yrs
* 90% by 6yrs
* 10% during school yrs
34
MODERATE VSDs
* 3-5mm diameter
* least common group of children(3-5%)
* w/o evidence of ccf/ pulm.htn can be
followed until spontaneous closure
occurs.
LARGE VSDs WITH NORMAL PVR
* 6-10mm in diameter
* usually requires surgery Conservative
treatment
35
36
DEFINITION
Patent ductus arteriosus
(PDA) is a heart problem
that is usually noted in
the first few weeks or
months after birth. It is
characterized by a
connection between the
aorta and the pulmonary
artery, which allows
oxygen-rich (red) blood
that should go to the
body to re-circulate
through the lungs
37
IN DEPTH
38
IN GROSS
39
HEMODYNAMICS
LT TO RT SHUNT
Occurs both during
systole & diastole
LARGE AMT Of blood
passes thru pulm
ART-LT ATRIUM
MITRAL VALVE
Large flow thru lt
vent-delayed closure
of aortic valve
Dilatation of
CONTINOUS
MURMUR
Accentuated s1
Mitral delayed
diastolic murmur
Late a2
Paradoxically split s2
Aortic ejection click
Aortic ejection systolic
murmur
40
HEMODYNAMICS
LATE A2
PARADOXICALLY
SPLIT S2
AORTIC EJECTION
CLICK
AORTIC EJECTION
SYSTOLIC
MURMUR
41
PRESENTATION
On examination
Inspection
Carotid pulsations
Hyperkinetic & lt
ventricular type of
apical impulse
Palpation
Systolic or
continous thrill at
2nd lt interspace
43
Auscultation
Accentuated s1
Narrowly or paradoxically split s2
Loud p2
Continous/gibsons/train-in-tunnel
murmur best heard in infraclavicular
region
Mitral delayed diastolic murmur
44
CXR FINDINGS
CARDIOMEGALY
LA ENLARGEMENT
LV ENLARGEMENT
PROMINENT
AORTIC KNUCKLE
PULM PLETHORA
45
ECG CHANGES
46
ECHO PICTURES
47
MANAGEMENT
MEDICAL
INDOMETHACIN 0.1
mg/kg/dose,orally,bd for three doses
Digoxin for increasing working capacity
of heart
Diuretics to reduce preload on heart
48
49
50
Narrowing in
proximal descending
aorta
May be long/tubular
but most commonly
discrete ridge
Natural hx: poor
prognosis if
unrepaired
Aortic
Aneurysm/dissection
CHF
Premature CADz
52
53
CLINICAL
Rib notching
55
Treatment
57
Tetralogy of Fallot
4 features
Malalignment VSD
Overriding Aorta
Pulmonic Stenosis
RVH
Variability correlates
with degree of RVOT
obstruction and
size/anatomy of PA
58
59
60
61
62
63
64
65
Complete Repair
Ebsteins Anomaly
www.ucch.org
Massive cardiomegaly,
mainly due to RAE
68
Pediatric
murmur
exercise intolerance
Eisenmengers Syndrome
70
71
72
Eisenmenger Complications
Coagulopathy/platelet consumption
Brain abcesses
Cerebral microemboli
Airway hemorrhage
especially moving from lowerhigher
altitudes (air travel, mountains)
73
Eisenmenger: Treatment
75