Mycoses

Oleh :
Efrida Warganegara

MYCOSES
Superficial mycoses
Cutaneous mycoses
Subcutaneous mycoses
Systemic mycoses :
pathogenic
opportunistic

Superficial Mycoses

Oleh :
Efrida Warganegara

SUPERFICIAL MYCOSES
Disease

Agent

Pityriasis versicolor

Malassezia furfur

Pityriasis nigra

Exophiala hortae

Black piedra

Piedraia hortae

White piedra

Trichosporon
beigelii

PITYRIASIS VERSICOLOR = Tinea versicolor

caused by Malassezia furfur (Pityrosporum
obiculare) is part of normal flora of the
skin & scalp ---> the infections may be
endogenous
the organism is lipophilic, requiring lipid for
growth
Pityriasis versicolor is a chronic, mild,
asymptomatic infection of the stratum
corneum; lesion are sharply delineated,
noninflamatory & cover with
furfuraceous
scales

PITYRIASIS VERSICOLOR
the term versicolor is particularly
appropriate, since color of the lesion varies
according to the normal skin pigmentation,
exposure to sunlight & severity of infection
lesion occur more often on the upper body,
face, neck, arm
the reason for a change from normal flora
status to a pathogenic agent are not
clear

PITYRIASIS VERSICOLOR
Laboratory diagnosis :
under uv ligth (Woods lamp) ---> Fluoresence : yellow
wet mount of skin scales : lesion contain short typical
elements & spherical cells (yeast) & this observation
is virtually pathognomonic (spaghetti & meat ball
appearance)
culture identification is not diagnostic (may be positive
from noninfective person); but the organism can be
cultured onto SDA (Sabouraud dextrose agar) covered
with olive oil
Treatment : selenium sulfide, sodium thiosulfate,
miconazole; but recurrent is frequent.

SUPERFICIAL MYCOSES
PITYRIASIS NIGRA = Tinea nigra = Tinea nigra palmaris
is caused by Exophiala werneckii; a dematiaceous fungus
is a superficial, chronic & asymptomatic infection of the
stratum corneum; is frequently found in the palm of the
hand,
characterized by brownish color which is often
darker at the edge of the macule
because infection may resemble melanoma or other types
skin cancer; a diagnosis of a fungal etiology is important

of

skin scraping examined for fungal element, reveal pigmented

hyphae
Treatment : keratolytic agent such as salicylic acid or sulfur
have been used; topical miconazol

SUPERFICIAL MYCOSIS
BLACK PIEDRA

caused by Piedraia hortae; mostly in tropical climate

infection of hair shaft (of the scalp), characterized by black,

hard nodules on the hair shaft; very difficult to remove the
nodules

in some area of the world, the infection may be encouraged for

cosmetic purpose

diagnosed by direct examination of the hair & nodules; reveals

hyphal strands are often aligt along the periphery of the mature
nodules; and the center of the mass resembles organized tissue
with area in which asci are produced

Treatment : by cutting the hair

SUPERFICIAL MYCOSIS
WHITE PIEDRA

caused by Trichosporon beigelii; mostly in

temperate climate

infection of hair shaft (moustache; axilla;

pubis); characterized by soft, light-colored
nodules of the hair sharf, easily to remove

direct examination of the hair sharf reveal the

mass of intertwined hyphae of the nodules;
often fragmented into arthroconidia

Treatment : by cutting the hair