Professional Documents
Culture Documents
No two hemispheres of
any learned professors
brain are equal to two
healthy mammary
glands in the production
of a satisfactory food for
infants
- Oliver Wendell Holmes
Human Milk
Colostrum
Distribution of Kcals
Breastmilk
Formula
% Protein
% Fat
52
48
% Carbohydrate
42
42
Protein:
Predominant protein of human milk is whey &
predominant protein in cows milk is casein
Casein: proteins of the curd (low solubility at
pH 4.6)
Whey: soluble proteins (remain soluble at pH
4.6)
Ratio of casein to whey is between 40:60 and
30:70 in human milk and 82:18 in cows milk
some formulas provide more whey proteins
than others
Characteristics and
Advantages of Human Milk
Breastmilk and
establishment of core
microbiome
Microbiome
Nutrient metabolism
Tissue development
Resistance to colonization with
pathogens
Maintenance of intestinal homeostasis
Immunological activation and
protection of GI integrity
Prebiotics,probiotics
Allergies: Breastmilk
AAP statement on
breastfeeding (continued)
AAP statement on
breastfeeding (continued)
Breast feeding
Human Milk
Substitutes
Science, Medicine
and Industry
Maternal BF
Wet nurses
Wealthy women
Orphans, abandoned, illegitimate
Prematurity or congenital deformities
Wet nurses
Other mammalian milk (cow, goat,
donkey, camel)
Pablum: bread/flour, mixed with
water
Historical timeline
1900
Pasteurization of milk
in US
Association between
bacteria and diarrhea
1912
U.S Childrens Bureau
Public Health and
Pediatricians efforts
to improve
infant/child health
and decrease
mortality
1920
Intro evaporated milk
Cod liver oil prevents
rickets
Curd tension of milk
altered
Increased availability
of refrigeration
Vitamin C isolated
Vitamin D prepared in
pure form
Improved sanitation
Historical timeline
1940
Homogenized milk
widely marketed
1960
Further advances in
technology and
packaging
Commercially
prepared infant
formula becoming
increasingly popular
1915 Gerstenberger
developed first complete
infant formula marketed as
SMA (synthetic milk adapted)
INFANT FORMULA
Formula Composition
Formula Brands
Ross
Mead Johnson
Good Start
Wyeth
Enfamil/Prosobee/Enfacare
Nestle
Similac/Isomil/Alimentum
SHS
NeoCate, DuoCal
Carbohydrate: lactose
DHA/ARA
Prebiotics/Probiotics
Fiber
Organic
Other
Soy Formulas
Soy Formulas
Isomil/Isomil DF /Isomil
Advance/Isomil Advance 2
Prosobee/Prosobee Lipil/Next
Step Prosobee
Soy Formulas
Characteristics compared to Milk
Based
Higher protein (lower quality)
Higher sodium, calcium, and
phosphorus
Carbohydrate: Corn syrup solids,
Should we be Concerned?
- Badger et al.
Contraindications to Soy
Formula: AAP
Predigested protein
based infant formulas
Protein Hydrolysate
Formulas
Alimentum Advance
Pregestimil/Pregestimil Lipil
Nutramigen Lipil
Hydrolysate Formulas
NeoCate (SHS)
Protein: Free Amino Acids
Fat: Long chain
Carbohydrate: Lactose Free
Indications for use: Food Allergy
or intolerance to peptides or
whole protein
Portagen
Similac PM 60/40
(Mead Johnson)
85% fat MCT, 15% fat Corn oil
Used for infants with chylothorax
(Ross)
Low in Ca, P, K+ and NA; 2:1 Ca:P ratio
Used for infants with Renal Failure
Premature Formulas
General Characteristics compared to
Standard
up to 2000-2500gm
NeoSure Advance
EnfaCare Lipil
Considerations
Evidence Based
Rationale
Indications
Soy
Vegetarian
Galactosemia
Protein Hydrolysates
Protein intolerance/allergy
other
Preterm Formulas
Post-discharge Preterm formulas
Other Specialty Formulas
Regulation of Infant
Formula
FDA
Infant Formula Act
Manufacturers
Voluntary monitoring
AAP, National Academy of Sciences,
other professional organizations
Guidelines for composition and
intake: (e.g. DRIs)
Guidelines for preparation and
handling of formula/human milk in
health care facilities
Formula Regulation
Regulation of Infant
Formulas
Regulation of Infant
Formulas
Manufacturing regulations
Quality control
Recall Proceedures
Nutrient content and labeling
Panel convened 1998 and 2002
(recommended revisions including
exemptions)
Formula safety
Present in BM
GRAS
Vitamin/mineral content conforms to
regulation
? testing
Finding Up to Date
Information
www.shsna.com/html/Hypoallergenic.htm
Neocate formulas
Additional concerns/issues
safety
Preparation
miscellaneous
Objections include:
Protein
RSL
Folic acid, iron, vitamin D
pasteurization
Milk Feedings
Cautionary Tales
Cooper, cont.
Cooper, cont.
Keating
Lucas
Formula Preparation
Microwave Protocol (Sigman-Grant,
1992)
Bright Futures
AAP/HRSA/MCHB
http://www.brightfutures.org
Bright Futures is a practical
development approach to
providing health supervision for
children of all ages from birth
through adolescence.
Newborn Visit:
Breastfeeding
Infant Guidance
Newborn Visit:
Breastfeeding
Maternal care
rest
fluids
relieving breast engorgement
caring for nipples
eating properly
First Week
One Month
Four Months
Continue to breastfeed or to use ironfortified formula for the first year of the
infant's life. This milk will continue to be
his major source of nutrition.
Begin introducing solid foods with a
spoon when the infant is four to six
months of age.
Use a spoon to give him an iron-fortified,
single-grain cereal such as rice.
Ben
Kali