Professional Documents
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FUNCTION
TESTS
By
doctoroid
1) Excretory – primary :by urine formation
2) Regulation of volume & electrolyte
composition of ECF
3) Regulation of acid-base balance
4) Endocrine function – produce & secrete:
erythropoietin, renin, calcitriol(1,25-
DHCC)
5) Site of neoglucogenesis – not primary: in
starvations- esp. from glutamine
collective term for a variety of individual tests and
procedures that can be done to evaluate how well
the kidneys are functioning.
Primarily reflects two basic mechs.– Glomerular
ultrafiltration & Tubular reabsorption/secretion
Practically, divided into 3 groups –
Anuria ,Oliguria
binding)
No tubular reabsorption/secretion
B) Endogenous >>
1) Creatinine (marginally overestimates—most widely
used in clinical practice)
2) Urea (one of the 1st markers– not used at present)
Approximation of bedside GFR with limited
accuracy by “Cockroft & Gault formula”
Most widely used & best validated for adults
MICROELECTRODE studies