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Autoimmune Inner Ear Disease
Autoimmune Inner Ear Disease
Autoimmune inner ear disease, as the term suggests is an immune disorder that
affects the structure of the inner ear. To better understand the condition, here is a
brief description about immune disorders and the ear structure. The immune
system is a part of the human body that helps to fight off infections and diseases
by attacking foreign bodies or microorganisms like bacteria, viruses and fungi that
are often responsible for infections. But in some cases this system malfunctions.
In such circumstances, the individuals immune system may turn on the body
itself and begin targeting healthy cells. This is known as an autoimmune disorder.
Autoimmune inner ear disease or AIED is basically an inflammatory condition that
affects the inner ear and is caused by an attack of the immune system on cells of
the inner ear. This is a relatively rare condition and is believed to be responsible
for less than 1 percent of all cases of hearing impairment.
The signs and symptoms of autoimmune inner ear disease are not always easy
to recognize, as they can often be confused with otitis media symptoms. Typical
symptoms include the following:
Progressive deterioration in hearing in both ears with hearing loss occurring
over weeks or
months. One ear may be affected before the other.
Sensations of fullness and blocked ear are not uncommon.
Dizziness and vertigo may also be observed.
Tinnitus is another symptom that is rather common and patients may notice a
ringing or constant hissing sound in the ear.
Lab tests can help and will evaluate certain parameters as part of an immune
screen. These include:
Erythrocyte sedimentation rate
Rheumatoid factor
Anti-nuclear antibody titer
Quantitative immunoglobulin determination
Leukocyte migration inhibition test
Some additional tests that are used include the following:
A Complete Blood Count or CBC
FTA/ABS blood screen
MRI, with contrast, of brain and cerebellopontine angle
Lymphocyte blast transformation
Lipid panel
Steroid trial