ALLERGIC CONTACT DERMATITIS

TO POVIDONE-IODINE: CASE REPORT

Fakultas Kedokteran Universitas Trisakti
KEPANITRAAN KLINIK ILMU KESEHATAN KULIT DAN KELAMIN
Rumah Sakit TNI AL DR. MINTOHARDJO
Periode 14 September 17 Oktober 2015
By : Rachma Tia Wasril (030.10.228)
Advisor : Suswardana

Introduction

Antiseptic
Most Commonly
used

Povidone-iodine

Short lasting action

Chemical burn
Irritant

Demir E, O'Dey DM, Pallua N. Accidental burns during surgery.J Burn Care Res.2006;27:895900.
Iiljma s, Investigation of irritant skin reaction by 10% povidone-iodine solution after surgery. Dermatology.2002;204
Suppl 1:103-8.

Introduction

Povidoneiodine

Allergy

Lopez Saez.Acute IgE-mediated generalized urticaria-angioedema after topical application of

povidone-iodine.in: Allergologia et Immunopathologia.1998 ed.26(1):23-26

Identity
Mr. Y

19 y.o.

Depok

Student

male

Subjective

2 weeks ago

1 week ago

2 day ago

Had ORIF on left

forearm

Clean itu with

povidone iodine

Itching
edema
Eritema

Objective

Normal Vital sign

BP: 120/80 mmHg
HR: 80
RR :20

Temprature : 36,5 C

Physical examination
Generalisata : Normal

Treatment
Education
Avoid all variant contains of povidone-iodine.

Drug

azithromycin 500 mg
cetirizine 10 mg
cream dexosimethason 2,5 mg (inerson cream)
compress NaCl 0,9%

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ALLERGIC
CONTACT
DERMATITIS

FASE
SENSITIZATI
ON
FASE
ELICITATION

IRRITANT

Bickers DR et al: The burden of skin diseases: 2004 a joint project of the American Academy of Dermatology association and the
society for Investigative dermatology. J Am Acad Dermatol 55:490, 2006

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NikhilDhingra, NicholasGulati and EmmaGuttman-Yassky. Mechanisms of Contact Sensitization Offer Insights into
the Role of Barrier Defects vs. Intrinsic Immune Abnormalities as Drivers of Atopic Dermatitis.

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Betadine
iodineandpolyvinylpyrrolidone(PVP)
364.950 Dalton
5%povidone-iodine(0.5%
availableiodine)

ZAMORA, Jose L. Chemical and microbiologic characteristics and toxicity of povidone-iodine solutions. The American
journal of surgery, 1986, 151.3: 400-406.

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Allergy Contact Test

Patch Test

Repeated
Open
Aplication
Test

LACHAPELLE, JeanMarie. Allergic contact dermatitis from povidoneiodine: a reevaluation

study.Contact Dermatitis, 2005, 52.1: 9-10.

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Thank you