BARIUM

SULFATE
Macalintal, Daine A.
Macalipay, Shaen
Mari Juan, Coleen
 Chemical Formula: BaSO4

It is a salt composed of the barium cation

(Ba2+) and the sulfate anion (SO42- ), in which
sulfur is attached to four oxygen atoms. The
barium metal is in the +2 oxidation state.
SYNONYMS
tif
blanc fixe
baryte
baraflave
baricon
PHYSICAL AND CHEMICAL
PROPERTIES

Pure barium sulfate is

found as white, odorless
powder or small crystals
with a density of 4.49
g/mL
melting point of 1580 C
and
boiling point of 1600 C
 SYNTHESIS
Barium sulfate is obtained in commercial amounts
from the mineral barite, after mining and
processing. The processing of the impure barite
involves heating it with coke (carbon) to form the
water-soluble barium sulfide (BaS), which is then
separated from the impurities and reacted with
sulfuric acid to give the pure barium sulfate product:
BaSO4+ 4 C BaS + 4 CO
BaS + H2SO4 BaSO4+ H2S

Another method to obtain pure barium sulfate is by

reacting barium carbonate or barium chloride with
sulfuric acid.
 USES
Drillingfluids
Pigment
Paper brightener
Plastics filler
Niche uses
PHARMACEUTICAL USES
radiopaque agent
MOA
Barium sulfate increases the absorption
of x-rays as they pass through the body,
thus delineating body structures, in
which barium sulfate is localized.
 TOXICITY
Exposure Routes
The substance can be absorbed into the body by
inhalation of its aerosol.
Inhalation, skin and/or eye contact

Symptoms
Irritation eyes, nose, upper respiratory system;
benign pneumoconiosis (baritosis)

Target Organs
- eyes, respiratory system
AVAILABLE PREPARATIONS
Dosage forms:
Suspensions
Cream
Powder for Suspension
Enema
Paste
Tablet
Liquid
QFR
Precautions

For oral administration of barium sulfate: Not

eating after 8 in the evening; not drinking
liquids after midnight

For rectal administration of barium sulfate:

Eating residue-free meals and using a laxative
on day before examination

Increased intake of liquids to prevent

impaction after oral administration
REFERENCES
http://www.reade.com/products/tif-bari
um-sulfate-baso4
http://www.softschools.com/formulas/che
mistry/barium_sulfate_uses_properties_s
tructure_formula/294/
https://
www.drugs.com/mmx/barium-sulfate.htm
l