NIDAsmissionistobringthe

powerofsciencetobear
ondrugabuseandaddiction.

PhotocourtesyofNIDA.
 PhotocourtesyoftheNIDAWebsite.FromA
SlideTeachingPacket:TheBrainandthe

ActionsofCocaine,Opiates,andMarijuana.
 Illustrationusedwithpermission,
courtesyofLydiaV.Kibiukand
theSocietyforNeuroscience.

PhotocourtesyoftheNIDAWebsite.FromA

SlideTeachingPacket:TheBrainandthe
ActionsofCocaine,Opiates,andMarijuana.

PhotocourtesyoftheNIDAWebsite.
FromASlideTeachingPacket:The
BrainandtheActionsofCocaine,
Opiates,andMarijuana.
Positron Emission Tomography (PET)

Your Brain on Drugs

1-2 Min 3-4 5-6

6-7 7-8 8-9

9-10 10-20 20-30

PhotocourtesyofNoraVolkow,Ph.D.Mappingcocainebinding
sitesinhumanandbaboonbraininvivo.FowlerJS,VolkowND,

WolfAP,DeweySL,SchlyerDJ,MacgregorRIR,HitzemannR,
LoganJ,BendreimB,GatleyST.etal.Synapse1989;4(4):371
377.
 Your Brain After Drugs

Normal

Cocaine Abuser (10 days)

Cocaine Abuser (100 days)

PhotocourtesyofNoraVolkow,Ph.D.VolkowND,HitzemannR,WangCI,FowlerIS,WolfAP,DeweySL.Longtermfrontalbrainmetabolicchangesincocaine
abusers.Synapse11:184190,1992;VolkowND,FowlerJS,WangGJ,HitzemannR,LoganJ,SchlyerD,Dewey5,WolfAP.DecreaseddopamineD2receptor
availabilityisassociatedwithreducedfrontalmetabolismincocaineabusers.Synapse14:169177,1993.
 Drugs Have
Long-term
Consequences

PhotocourtesyofNIDAfromresearchconductedby
MelegaWP,RaleighMJ,StoutDB,LacanC,HuangSC,
PhelpsME.

 The Memory of Drugs

Amygdala Amygdala
not lit up activated
Front of Brain

Back of Brain

Nature Video Cocaine Video

PhotocourtesyofAnnaRoseChildress,Ph.D.

 The good news is

Drug Abuse is a
preventable behavior
and

Drug Addiction is
a treatable disease

CourtesyofPartnershipforaDrugFreeAmerica.
 Is it
worth
the risk?

PhotocourtesyofNIDA.
 Visit NIDAs Web Site at:
http://www.drugabuse.gov

PhotocourtesyofNIDA
 Have you changed your mind?

PhotocourtesyofNIDA.IfYouChangeYourMind.
Studentmagazine.NIHPublicationNo.933474,1993.