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Understanding Diuretics: Types & Uses

Diuretics work by inhibiting sodium reabsorption in the kidneys, which leads to increased sodium and water excretion. There are several classes of diuretics that work through different mechanisms including inhibiting the Na-K-2Cl symport, Na-Cl symport, Na channels, or mineralocorticoid receptors. Common diuretics are loop diuretics like furosemide, thiazide diuretics like hydrochlorothiazide, K-sparing diuretics like triamterene, and mineralocorticoid receptor antagonists like spironolactone.

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Ethar Love
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63 views13 pages

Understanding Diuretics: Types & Uses

Diuretics work by inhibiting sodium reabsorption in the kidneys, which leads to increased sodium and water excretion. There are several classes of diuretics that work through different mechanisms including inhibiting the Na-K-2Cl symport, Na-Cl symport, Na channels, or mineralocorticoid receptors. Common diuretics are loop diuretics like furosemide, thiazide diuretics like hydrochlorothiazide, K-sparing diuretics like triamterene, and mineralocorticoid receptor antagonists like spironolactone.

Uploaded by

Ethar Love
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PPT, PDF, TXT or read online on Scribd

DIURETICS

HOW DO THEY WORK?


What do they do?
When do I use them?
How do I use them?
EPITHELIAL
TRANSPORT
MECHANISM
OF ACTION
Na-K-2Cl SYMPORT
INHIBITORS
Also Called:
Loop Diuretics
High Ceiling Diuretics

Ethacrynic
Furosemide
Acid

Bumetanide Torsemide
Na-Cl SYMPORT INHIBITORS

Also Called:
Thiazide Diuretics
Thiazide-Like Diuretics

Hydrochlorothiazide Chlorthalidone

Chlorothiazide Metolazone
Na CHANNEL
INHIBITORS
Also Called:
K-Sparing Diuretics

Triamterene

Amiloride
MINERALOCORTICOID
RECEPTOR ANTAGONISTS

Also Called:
K-Sparing Diuretics
Aldosterone Antagonists

Spironolactone

Eplerenone

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