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  • Lepto Spiros Is

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    Izza Tanzihul
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    Leptospirosis is caused by spirochete bacteria called Leptospira interrogans. The bacteria can survive for weeks in water or soil and infect humans through contact with contaminated water or food. Common symptoms include fever, hepatitis, jaundice, kidney failure, and meningitis. Diagnosis involves isolating the bacteria from blood or urine samples or detecting antibodies in the blood. Penicillin and doxycycline are used to treat the infection if administered early. Prevention focuses on rodent control and protective measures for those exposed through work.

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    leptospirosis

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    Leptospirosis is caused by spirochete bacteria called Leptospira interrogans. The bacteria can survive for weeks in water or soil and infect humans through contact with contaminated water or food. Common symptoms include fever, hepatitis, jaundice, kidney failure, and meningitis. Diagnosis involves isolating the bacteria from blood or urine samples or detecting antibodies in the blood. Penicillin and doxycycline are used to treat the infection if administered early. Prevention focuses on rodent control and protective measures for those exposed through work.

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    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
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    4 views5 pages

    Lepto Spiros Is

    Uploaded by

    Izza Tanzihul
    Leptospirosis is caused by spirochete bacteria called Leptospira interrogans. The bacteria can survive for weeks in water or soil and infect humans through contact with contaminated water or food. Common symptoms include fever, hepatitis, jaundice, kidney failure, and meningitis. Diagnosis involves isolating the bacteria from blood or urine samples or detecting antibodies in the blood. Penicillin and doxycycline are used to treat the infection if administered early. Prevention focuses on rodent control and protective measures for those exposed through work.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
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    of 5

    LEPTOSPIROS

    IS

    EfridaWarganegara
    AETIOLOGYANDTRANSMISSION

    Leptospirosisaretightlycoiledspirochaetes,
    515umlong
    Activerotationalmovementandhave2
    flagella
    Bestseenbydarkfieldmicroscopybecause
    notverywellstainedbydyes
    Leptospirainterrogeransquestionmark
    likehookattheendofm.o.
    Thisspesiesingectsmammalsasrats,
    causingchronickidneysinfectionwith
    excretionoflargenumbersofbacteriain
    urine
    AETIOLOGYANDTRANSMISSION
    Bacteriaaresoonkilledondrying,heating,
    exposuretodetergentsordesinfectans
    Theyremainviableforseveralweeksin
    stagnantalkalinewaterorwetsoil.
    Humanareinfectedbyingstionofor
    exposuretocontaminatedwaterorfood
    Bacteriabymotilityenterthrough
    breaksinskinormucosae,sothatinfection
    canbeacquiredbyswimming,workingor
    playingincontaminatedwater
    Bacteriaareexcretedinhumanurinebut
    persontopersontransmissionisrare
    CLINICALFEATURESANDPAHOGENESIS
    Bacteriareachthebloodandafteranincubation
    periodof12weeks,causeafebrile,influenzaelike
    illness
    Multiplicationinliverhepatitis,jaudiceand
    hemorrhage;inkidneyuremiaandbacteriuria;
    inCSFandhumoraquosasepticmeningitis;in
    eyeconyuctivalandscleralhemorrhage
    Theclinicalpicturedependtosomeextentonthe
    particulartypeofleptospire
    WeillsDiseasesevereformwithhaemorrhagic
    complicationandkidneyandliverfailureoccurs
    inonly510%ofpatientsillwithleptospirosid
    DIAGNOSIS,TREATMENTAND
    PREVENTION
    Thereisoftenahistoryofexposure

    Bacteracanbeisolatedfromblood,CSF,and
    urine
    Riseinagglutinationantibodycanbe
    demonstrated
    Penicillinandtetracyclinhavebeenvaluablein
    treatmentwhengivenadayortwoofonsetof
    llness
    Doxycyclinewillpreventdiseaseinthose
    exposedtoinfection
    Measuresforpreventionincluderodentcontrol,
    protectiveclothingandprophylacticpenocillin
    aftercutsandabrasionsinthoseatrisk

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