Honey- Honey consists of simple sugars and is both
sterile and inhibits growth of both Gram-negative and Gram-positive organisms. Its antibiotic properties are attributed to its low pH, a thermolabile substance called inhibine, and its hygroscopic properties.
Molan summarized the clinical base evidence
supporting the use of honey as a wound dressing. This review reported the findings of 17 randomized controlled trials involving 1965 participants, as well as 5 clinical trials of other forms involving 97 participants treated with honey. Alternative Medicinals The wound types treated with honey during these control trials were either superficial burns, partial thickness wounds, moderate burns, third degree burns, chronic leg ulcers, pressure ulcers, and surgical wounds.
These studies compared honey to either silver
sulfadiazine, amniotic membrane, Vaseline gauze, an occlusive dressing, mupirocin, povidone-iodine, or a boiled potato peel.
Commercial products released in 2007
Alternative Medicinals This review presents a large body of evidence supporting the use of honey as a wound dressing for a wide range of wounds because its antibacterial activity rapidly clears infection and protects the wound and it provides a moist healing environment without the risk of bacterial growth occurring. Also, honey rapidly debrides wounds and removes malodor and its anti- inflammatory activity reduces edema and exudate and prevents or minimizes hypertrophic scarring.