Scribd Logo
Upload

Welcome to Scribd!

  • Schema of Androgen Action

    Uploaded by

    Ezi Nurul
    13 views4 pages
    Androgens like testosterone and DHT activate cells by binding to androgen receptors in the cell. This causes the receptors to dimerize and become phosphorylated, recruiting co-activators that allow the receptor complex to bind to DNA at androgen response elements and activate target genes, producing a biological response.

    Original Description:

    Schema of Androgen Action.ppt

    Copyright

    © © All Rights Reserved

    Available Formats

    PPT, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    Androgens like testosterone and DHT activate cells by binding to androgen receptors in the cell. This causes the receptors to dimerize and become phosphorylated, recruiting co-activators that allow the receptor complex to bind to DNA at androgen response elements and activate target genes, producing a biological response.

    Copyright:

    © All Rights Reserved
    Download as PPT, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    13 views4 pages

    Schema of Androgen Action

    Uploaded by

    Ezi Nurul
    Androgens like testosterone and DHT activate cells by binding to androgen receptors in the cell. This causes the receptors to dimerize and become phosphorylated, recruiting co-activators that allow the receptor complex to bind to DNA at androgen response elements and activate target genes, producing a biological response.

    Copyright:

    © All Rights Reserved
    Download as PPT, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 4

    SCHEMATIC OF ANDROGEN ACTION

    Testosteron
    SHBG
    5-reductase DHT
    HSP
    Ligand
    Androgen-responsive cell Binding

    P P HSP

    Dimerization and phosphorylation

    Co-activator
    P P recruitment

    DNA GTA

    binding

    Target Gene Activation


    Androgen-response element
    Biological response
    Testosteron
    SHBG
    5-reductase DHT
    HSP
    Ligand
    Androgen-responsive cell Binding

    P P HSP

    Dimerization and phosphorylation

    Co-activator
    P P recruitment

    DNA GTA

    binding

    Target Gene Activation


    Androgen-response element
    Biological response
    Testosteron
    SHBG
    5-reductase DHT
    HSP
    Ligand
    Androgen-responsive cell Binding

    P P HSP

    Dimerization and phosphorylation

    Co-activator
    P P recruitment

    DNA GTA

    binding

    Target Gene Activation


    Androgen-response element
    Biological response

    You might also like