BEHAVIORAL CONDITIONING As substance users continue consumption, their Central Nervous System (CNS) becomes conditioned to respond to environmental factors it associates with intake.
Compensatory response increases over time
Without the typical environmental factors, CNS doesn't respond and intoxication occurs much more quickly. This leads to overdoses.
Depressant effect without the CRS
stimulant response to counteract it This CNS response has also been linked to addictive withdrawal as the CNS stimulation, when not met with the users normal substance, causes symptoms of its own.
Stimulant effect without the substance-
initiated depressant effect to counteract it CNS response can be used in treatment as people can be re- conditioned via decreasing exposure rather than cold turkey approaches