Psychological disorders are:
dysfunctional
melee
Terms from the Definition
Disorder refers to a state of
mental/behavioral ill health.
Patterns refers to finding a collection
of symptoms that tend to go together,
and not just seeing a single
symptom.
For there to be distress and
dysfunction, symptoms must be
sufficiently severe to interfere with
one’s daily life and well being.
Deviant means differing from the
norm.A Pinu eeu
“Deviant”? The Role of Context and
Culture
Desai
To deviate, in general, Er ei el
means to vary from r i ope
what typically would
happen. Bae
In psychology, a < the
behavior or mental leer
state is considered bh Sle
deviant by a culture
when it is different from
what woul
expected in that
culture.
A disorder may also be
a deviation froma
typical developmental
pathway.Is Attention-Deficit/
Hyperactivity Disorder (ADHD)
a disorder?
" Is it deviant? Do some people have a level of
inattentiveness, impulsiveness, or restlessness that
goes beyond laziness or immaturity?
" Is it distressful? Is the person enjoying being
energetic, or are they frustrated that they can’t
sustain focus?
= Is there dysfunction? Are the symptoms harmless
fun, or do they negatively impact work and
relationships?Understanding the Nature of
Psychological Disorders
™ One reason to diagnose a disorder is to make
decisions about treating the problem.
= To treat a disorder, it helps to understand t!
nature/cause of the psychological symptoms:
" Based on older understanding of
psychological disorders,
treatments have included:
exorcising evil spirits, beatings,
caging/restraint, and —————>* Philippe Pinel (1745-1826) and others
sought to reform brutal treatment by
promoting a new understanding of the
ature of mental disorders.
* Pinel proposed that mental disorders Pacenuencinpraved
were not caused by demonic possession, [lives but often Get ROE
but by environmental factors such as effectively reat mental
stress and inhumane conditions.
* Pinel's “moral treatment” involved
the mentally ill:
Pinel’s humane
environmental
improving the environment and But
replacing the asylum beatings with hyper-elevated mood that
is euphoric, giddy, easily
irritated, hyperactive,
impulsive, overly optimistic,
and even grandiose.
Gene
Depressed mood: stuck feeling
“down,” with:
exaggerated pessimism
social withdrawal
lack of felt pleasu
inactivity and no i
difficulty focusing
fatigue and excessive desire to
sleep
ative
‘Mania: euphoric, giddy, easily
irritated, with:
" exaggerated optimism
hypersocialty and sexuality
delight in everything
impulsivity and overactivity
racing thoughts; the mind
won't settle down
little desire for sleepBipolar Disorder in Children and
BCE
Does bipolar disorder
show up before
adulthood, and even
before puberty?
Many young people
have cycles from
depression to
extended rage rather
than mania.
The DSM-V may have
a new diagnosis for
these kids: disruptive
mood dysregulation
disorder.Why Does Depression Have so
Many Symptoms?
hebletinen, quit, enpsiness,
+ eae eekly dsomnecid
konoten
+ Turning away from other people
** Insomnia, early morni
or oversieeping
iiiecetocaee
¢ Las ol physical and manal energyUnderstanding Mood Disorders
Can we explain...
™ why does depression
‘often go away on its own?
the course/development
of reactive depression?
Often, time heals a mood
disorder, especially when
the mood issue is in
reaction to a stressful
event. However, a
significant proportion of
people with major
depressive disorder do
not automatically or
easily get better with
time." Every year, 1 million people commit suicide, giving
Melk We eole tee) mea nach ae) STM eal
emotional well-being.
Bee Ma] >) Sama uN -ce) ol eR Te
trapped, isolated, ineffective, and see no end to
Ps
Non-suicidal self-injury has other functions sueh as
Fxo1aol Lal ae Mant ect) OMe Ls od Lavan |Understanding Mood Disorders
Evolutionary
Genetic
Brain /Body
Biological aspects and
een riCne
Negative thoughts and
Cer Renee esac negative mood
and explanations Explanatory style
The vicious cycle=—“Depression, inits milder, ron-
disordered form, may have
had survival value.
" Under stress, depression is
social-emotional hibernation.
It allows humans to:
™ conserve energy.
" avoid conflicts and other
risks.
" let go of unattainable
goals.
™ take time to contemplate.
MlBiology of Depression: Genetics
Evidence of genetic influence on depression:
1.DNA linkage analysis reveals depressed gene regions
2.twin/adoption heritability studies
90%
The heritability of various psychological
s disorders Researchers Joseph Bienvenu, Dimitry
70 Davydow, and Kenneth Kendler (2011) aggregated
data from studies of identical and fratemal twins
eo toestimate the heritability of bipolar disorder,
50 schizophrenia, anorexia nervosa, major depressive
ad disorder, and generalized anxiety disorder.
30 Il Bipolar disorder
on IH Schizophrenia
I Anorexia nervosa
Bi Major depressive disorder
0 J . 1 Generalized anaiety disorder
Heritability estimatesBiology of Depression au Brain
" Brain activity is diminished in depression and increased in
mania.
= Brain structure: smaller frontal lobes in depression and
fewer axons in bipolar disorder
= Brain cell communication (neurotransmitters):
™ more norepinephrine (arousing) in mania, less in
depression
™ reduced serotonin in depression
Depressed state Manic state Depressed state
nay 37) (May 18) (May 27)Preventing or Reducing Depression:
Using Knowledge of the Biology of DepressionUnderstanding Mood Disorders:
The Social-Cognitive Perspective
Discounting positive
information ane assuming the
worst about self, situation,
lear and the future Self-defeating
eet Beliefs such as
assuming that
Sm one (self) is
i Persea unable to cope,
improve, achieve,
or be happy
Depression is
associated with:
Prarie
Explanatory
airy
‘Stuck focusing on
what's badDepressive Explanatory Style
How we analyze bad news predicts mood.
Problematic event:
T
Assumptions about
the problem
Gone eaute steerer gtr tin
o
‘ital
F wines pts ant
eee Tete ca,
Ul
ATS Deeds ourbreskup was all my felt
it th ~
Mood/result that Sea
goes along with
these views:Depression’s Vicious Cycle
A depressed mood may develop when a person with a
negative outlook experiences repeated stress.
The depressed Sirecehit
mood changes a experiences
person’s style of
thinking and
; ee 7 2
interacting ina cogiitie and Negative
way that makes behavioral changes explanatory style
stressful
experience
more likely. 3
Depressed
moodSchizophrenia:
ed
Psychosis refers
to a mental split
from reality and
feeling
Ls
the mind is split from reality, e.g.
a split from one’s own thoughts
so that they appear as
LE) elec l iene
Schizophrenia
symptoms include:
"disorganized
, and/or delusional
thinking.
"disturbed
perceptions.
"inappropriate
ee emotions and
actions.Preaek
eae
iced ere
Pence sn]
perceptions), especially
Bri
PECAN
PSS ames sri
persecutory
Dee Runt ae
Presi e acd
CT aC Mery
Gein GOL urn
showing in the face)
Reet eel
interaction
PON OR aad
yur sule
Po as
Pura eae
focus on tasks)Schizophrenia Symptoms:
Problems in Thinking and Speaking
" Disorganized speech,
including the “word salad”
of loosely associated
phrases
* Delusions flusory belief),
often bizarre and not just
mistaken; most common
are delusion of grandeur
and of persecution
* Problems with selective
attention, difficulty
filtering thoughts and
choosing which thoughts
to believe and to say out
loud
Schizophrenia Symptoms:
Disturbed Perceptions
* Peoole with schizophrenia often &
experience hallucinations, that is,
perceptual experiences not e
shared by others,
* The most common form of
hallucination is hearing voices
that no one else hears, often with
Upsetting e.g, shaming) content.
* Hallucinations can algo be visual,
clfactory/smels,tactile/touch, or
gustatory/taste,Schizophrenia Symptoms: Schizophrenia Symptoms:
Inappropriate Emotions Inappropriate Actions/Behavior
* Odd and socially inappropriate Odd and socially inappropriate
responses such as looking bored behavior can be caused by symptoms
i while hearing of a suchas:
eat
"errors in social perception.
" Flat affect faial/body "disorganized, unfiltered thinking,
expression is “flat” with no
visible emational content @ @ "delusions and hallucinations. @@
" Impaired perception of
emotions, including not The schizophrenic body exhibits
“reacing’ others’ intentions and symptoms such a:
feelings — "repetitive behaviors such as rocking
and rubbing,
"catatonia, uch as siting motionless
and unresponsive for hours.Onset and
Development of
Nol rey yesyal es
Onset: Typically,
schizophrenic symptoms
appear at the end of
adolescence and in early
adulthood, later for
women than for men.
" Prevalence: Nearly 1 in 100
people develop
schizophrenia, slightly
more men than women.
= Development: The course
of schizophrenia can be
acute/reactive or chronic.
Course of
Schizophrenia
Acute/Reactive Schizophrenia
TeWec-laatelameensac-cHmcoluaT
people develop positive
symptoms such as
LENA LeCOn
alleen LV LCN
Chronic/Process Schizophrenia
develops slowly, with more
ies -claNory OOS onic nile
affect and social withdrawal.
Beak (tam ce -teltnrcanl at ale]
support, there may be
periods of a normal life,
folie gTel are ol om
— Without treatment, this
type of schizophrenia
often leads to poverty and
social problems.Subtypes of Schizophrenia
Ee
* Plagued by hallucinations, often with negative
messages, and delusions, both grandiose and
persecutory
OE
* Primary symptoms are flat affect, incoherent speech,
and random behavior
a
* Rarely initiating or controlling movement; copies
others’ speech and actions
Sirhan
* Many varied symptoms
Es
* Withdrawal continues after positive symptoms have
disappearednderstanding Schizophrenia
What's going on in Abnormal brain
the brain in > structure and
schizophrenia? activity
* Too many dopamine/D4 receptors
help to explain paranoia and
hallucinations; it’s like taking
amphetamine overdoses all the time.
Poor coordination of neural firing in
the frontal lobes impairs judgment
and self-control.
" The thalamus fires during
hallucinations as if real sensations
were being received.
There is general shrinking of many
brain areas and connections between
them.ndersta g Schizophrenia
Are there biological risk factors
affecting early development?
\
Biological Risk Factors
Schizophrenia is somewhat more
likely to develop when one or more of
these factors is present:
= low birth weight
maternal diabetes
older paternal age
famine
oxygen deprivation during delivery
maternal virus during mid-pregnancy
impairing brain developmentderstanding Schizo
Are there genetic risk factors?
If so, we would see more .
similar schizophrenia risk -» Genetic Factors
renia
shared between identical twins If one twin has
than fraternal twins (graph schizophrenia, the
below). Do we? chance of the other
Schizophrenia risk one also having it are
for twins of those much greater if the
diagnosed twins are identical.
with schizophrenia
70% | Mil Fraternal twins
60 | dentical wins Having adoptive
0 siblings (or parents)
“0 with schizophrenia
a does not increase the
- likelihood of
ae developing
a schizophrenia.
Japan Denmark Finland Germany U.K.
(1998) (1996) 4998) 6998) (999),Understanding Schizophrenia
Genetic and Prenatal Causes
* Even in identical twins, genetics do
not fully predict schizophrenia.
" This could be because of
environmental differences.
"First difference: twins in separate
placentas.
ecu
PM eae
trimester doubles the
Fite ee eae
rec M es
rn el Re
pecans had
Coogee
™ Genetics may
Tamed
Pires
eee arn
each
See eae a
neva’
Sura
factors to turn on
these genes.
Neschephee ‘Seen
Only one of two twins has the enlarged
ventricles seen in schizophrenianderstanding Schizophrenia
Are there Social-_
psychological Psychological
causes? Factors
" Research does not support the idea
that social or psychological factors
(such as parenting) alone can cause
schizophrenia.
However, there may be factors such
as stress that affect the onset of
schizophrenia.
Until we find a mechanism of
causation, all we may have is a list of
factors which correlate with
increased risk.Prosieting Sctmsouivonte:
Early
early separation from
parents
short attention span
disruptive OR withdrawn
behavior
emotional unpredictability
poor peer relations and/or =
solitary play
arning Signs
factor:
d
before the onset
ete
having a mother with
severe chronic
schizophrenia
birth complications,
including oxygen
deprivation and low
birth weight
poor muscle
coordination" Dissociation refers to a separation of
Other Dever ti conscious awareness from thoughts,
4 ee memory, bodily sensations, feelings,
Disorders or even from identity.
* Dissociation can serve as a
psychological escape from an
overwhelmingly stressful situation.
" A dissociative disorder refers to
dysfunction and distress caused by
Examples: chronic and severe dissociation,
reer Loss of memory with no known physical cause;
inability to recall selected memories or any memories
mid
“Running away’ state; wandering away from one’s
Disorders MAMORU NAO euN Renu
aaa eee eCCSTs eros
In the rare actual cases of PA Different personales hve ;
D.LD. the personalities: VISTAS SI noted: ree
"are distinct, and not present PULSARS UMCUISN ferent bin uave 4
inconsciousness a the same fioullda iene oats, Sl
time. SOMO SCM ferent tht Ps
"may or may not appear to be dade ui gol f handedness,
aware of each other. Sol reuULUmamCA ferent viva auiy and
Ce aay eye muscle balance pattern.
Patints with DD. ago show
heightened activity in areas
ofthe brain associated with
managing and inhibiting
traumatic memories.
Omics
BERT UD TOM IaCd
errlcoKua URNS]
HC useC KONE
people to think of different
parts of themselves,These may involve:
"unrealistic body image and extreme
body ideal.
"a desireto control food and the
body when one’s situation can’t be
controled.
iy
Usa
Anorexia nervosa 4
Bina feo cycles of depression,
: _ "health problems,
Binge-eating disorder
PECL) oe) ae
Anorexia Compulsion tolose weight, O.6 percent
coupled with certainty about meet criteria at
it bag tng etn some time
or more underweight dling lifetime
Bulimia Compulsion to binge, eating large
Nervosa 2mtounts fst, then purge by losing LOpecent
the food through vomiting,
lavatives, and extreme exercise
Binge-Eating Compuson to bing, followed by
Disorder sult and depression 28percet
Eating Disorders: Associated Factors
Family factors:
"having a mother focused on her
weight, and on child's appearance
and weight
fete self-evaluation in the
family
for bulimia, if childhood obesity
runsinthe faily
for anorexia if families are
competitive, high-achieving, and
protective
Cultural factors:
"unrealistic ideals of body
appearancePersonality
Disorders
Personality kat
behavior that impai
social functioning
There are three “clusters”/categories of personality
disorders.
"Anxious: e.g., Avoidant P.D., ruled by fear of social
rejection
=Eccentric/Odd: e.g. Schizoid P.D., with flat affect, no
social attachments
"Dramatic: e.g. Histrionic, attention-seeking;
narcissistic, self-centered; antisocial, amoralAntisocial Personality Disorder [APD]
Antisocial personality
cisorder refers to acting
impubively or fearlessly
without regard for
others’ needs and
feelings,
The diagnostic criteria
include a pattern of
Violating the rights of
others since age 15,
including three ofthese:
About half of children
with persistent antisocial
behavior develop lifelong
Which kids are at risk?
Psychological factors:
"those who in preschool
were impulsive,
uninhibited,
unconcerned with social
rewards, and low in
anxiety.
"those who endured
child abuse, and/or
| inconsistent, unavailable
caretaking.
Biological APD Risk Factors
"Antisocial or unemotional biological
relatives increases risk.
* Some associated genes have
been identified.
*Risk factors include body-based
fearlessness, lower levels of stress
ASAE MAN Seo
arousal in stressful situations such as
awaiting receiving a shock.
"Fear conditioning is impaired,
"Reduced prefrontal cortex tissue
leads to impulsivity,
"Substance dependence is more
relAntisocial PD # Criminality
Criminals: people People with
Who repeatedly antisocial
commit crimes personality
disorder
Many career criminals do show empathy and
selflessness with family and friends,
Many people with A.P.D. do not commit crimes,
Antisocial Crime
If antisocial personality disorder is nota full picture of most
criminal activity, what can we say about people who
commit crime, especially violent crime?
Pecentage 35%
dtc
offenders
Bb
Biosoil rots of crime:
birth complications and"
poverycombineto
increase risk, 5
a
Ttalerime Thievery Violence
Chithood — Mosel
gety cals
With poet and
ltl complainsBiosocial Roots of Crime: The Brain
People who
commit murder
seem to have
less tissue and
activity in the
part of the
brain that
suppresses
impulses.
Normal Murderer
Other differences include:
"less amygdala response when viewing violence.
™an overactive dopamine reward-seeking system.Risks and Protective Factors for ;
Mental Disorders TCU TaN aU
Risk Factors Protective Factors Aaa vgn
Academic failure Aerobic exercise
Birth complications Community offering empowerment
Caring or chronically lor patients with dementia
Child abuse and neglect
Heer CaN AO LOa GOAN
0) coco ENON en NO
Mn Mats UA
treatment
Chronic insomnia
Chronic pain
Family disorganization or conflict
Low birth weight
Literacy
Postve attachment and early bonding
Low socioeconomic status
Medical liness Positive parent-child relationships
Neoctenial nblce Prem lings BT Vc0o a LUTION
Parental mental ili Resilient coping with stress and adversity
albeit ae mee
substance abuse
loss and bereavement Social and work skills
Gree ie Sec agporton aniyandnets METER o occ escacTU
ITU CeN SOU
Reading disabilities
Sensory disables Who is at risk of mental disorders?
Saliack Who is less at risk?