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Guillain-Barre Syndrome
Pembimbing : dr. Haryanto, Sp.S
Definisi
Acute Inflammatory Demyelinating Polyneuropathy (AIDP), an
autoimmune disease affecting the peripheral nervous system that is
usually triggered by an acute infectious process
Etiologi
• 6 minggu post infeksi (saluran napas atas atau gastroenterik)
• Epstein-Barr virus, Mycoplasma pneumoniae, Campylobacter jejuni,
cytomegalovirus
• Post Imunisasi
• Post operatif atau trauma kepala  ↓ depresi imunitas termediasi
sel & produksi antibodi antimyelin
• Penyakit lain : systemic lupus erythematosus, sarcoidosis, lymphoma,
snakebite
• Kehamilan
Epidemiologi
• Eropa 1.2–1.9/100,000,
• Dunia 0.6–4/100,000.
• Pria 1,5x > Wanita
• Insidensi meningkat dengan usia :
• 1 per 100,000 (<30th) – 4/100,000 (>75th)
• China, insidensi pd dewasa 0.66 /100,000.

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