Against Heresies (Adversus Haereses). • All his known writings are devoted to the conflict with the Gnostics. • Because Gnosticism was overcome through the efforts of the early Church Fathers, among them Clement of Alexandria and Irenaeus, Gnostic writings were largely obliterated. • Irenaeus asserted in a positive manner the validity of the Jewish Bible (the Old Testament), which the Gnostics denied, claiming that it upheld the laws of God the Creator. • The development of the creed and the office of bishop also can be traced to his conflicts with the Gnostics. • Although Gnosticism slowly died out after the 2nd century A.D., there are still gnostic Christians today. http://www.britannica.com/biography/Saint-Irenaeus http://www.catholic.com/tracts/the-great-heresies http://www.austindiocese.org/article/14488/saints-our-times-st- irenaeus-fought-growing-gnosticism-2nd-century http://www.britannica.com/biography/Saint-Clement-of- Alexandria