Ledipasvir/Sofosbuvir

Ledipasvir/Sofosbuvir
• Ledipasvir/sofosbuvir, sold under the trade
name Harvoni among others, is a medication
used to treat hepatitis C
• It is a combination of ledipasvir and sofosbuvir
• Cure rates are 94% to 99% in people infected
with hepatitis C virus (HCV) genotype 1
 About Ledipasvir/Sofosbuvir
• Ledifos 90Mg/400Mg Tablet helps in the
treatment of chronic hepatitis C (HCV).
• This drug is used in a combination with another
drug, to prevent the spread of HCV throughout
the body.
• Patients who have liver issues, or kidney
problems and are undergoing dialysis, are not
advised the use of Ledifos 90Mg/400Mg Tablet
• Also inform your doctor about any other health
issues you are suffering from and if you are taking
any medicines to treat them.
 Medical Uses
• Cure rates are 94% to 99% in people infected
with genotype 1 (46% of HCV cases).
• It has also been evaluated for the treatment of
infection with other hepatitis C genotypes,
and has shown promising results in genotypes
3 and 4
• (making up 30% and less than 22% of HCV
cases respectively)
 Side Effects
• More than 10% of people taking
ledipasvir/sofosbuvir have headaches or
fatigue; rashes, nausea
• Anemia
• Increased lipase
• Trouble breathing
• Irregular heartbeat
 Drug Interactions
• Ledipasvir/sofosbuvir is a substrate for the
drug transporters P-Glycoprotein (P-gp) and
breast cancer resistance protein (BCRP)
• Patients are also advised to stay away from H2
Receptor Antagonists (H2RA) and Proton
Pump Inhibitors (PPI) because they decrease
the concentration of ledipasvir
Images
 Precaution
• Risks related with ribavirin combination
therapy
• Caution with use in renal impairment and
hepatic impairment patients
• Serious bradycardia occurs while concomitant
with amiodarone
• Concurrent use of PgP inducers and Ledifos
tablet causes depletion in therapeutic effect
 Buy Online
• If You Want Ledipasvir/Sofosbuvir
Combination Tablet Online Visit Our Website.
• Website: https://applepharma.us
• Mail Id: applepharmaceutical@gmail.com
• Contact No: +91- 9987711567