Professional Documents
Culture Documents
(HIV)
1996
Zerit/Epivir/Crixivan 10 pills, Q8H
1998
Retrovir/Epivir/Sustiva 5 pills, BID
2002
Combivir (AZT/3TC)/EFV 3 pills, BID
2003
Viread/ Emtriva/Sustiva 3 pills, QD
2004
Truvada/Sustiva 2 pills, QD
Sustiva + Truvada Treatment
• Sustiva + Truvada (FTC + tenofovor) is one of the most
popular and effective starting HIV regimens.
• Many patients will have dream/sleep/central nervous
system effects particularly in the first month (due to the
Sustiva).
• Upset stomach/bloating/gas/loose stools is also fairly
common during the first month and for most patients is
fairly mild.
• HIV levels in the blood will often drop by > 99% in the
first month and the CD4 count (marker of immune
system function) will often increase providing protection
against AIDS related diseases within weeks/months of
starting the medication.
Truvada
• Truvada is made up of HIV drugs from a
class called nucleoside/nucleotide reverse
transcriptase inhibitors (NRTIs), also
known as “nukes.”
• The NRTIs block reverse transcriptase, a
protein that HIV needs to make more
copies of itself. This may slow down HIV
disease
‘typical’ primary HIV-1 infection
symptoms symptoms
HIV proviral DNA
HIV antibodies
‘window’
period
0 1 2 3 4 5 6 / 2 4 6 8 10
1° infection weeks years
Time following infection
Laboratory Diagnosis of HIV Infection
p68
p55
p53
gp41-45
Spectrum p40
p34
of anti-HIV p24
testing p18
p12
• http://pathmicro.med.sc.edu/lecture/HIV3.htm
• http://www.avert.org/hivstages.htm
• http://www.aidsinfo.nih.gov/guidelines/
• http://www.hopkins-aids.edu/publications/pocketguide/pocketgd0105.pdf
• http://www.modares.ac.ir/sci/saman_h/Pages/applications.htm
• http://hivinsite.ucsf.edu/InSite?page=kb-02&doc=kb-02-02-02-02
• http://www.hivandhepatitis.com/recent/test/realtime/061604_f.html