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  • Nausea and Vomiting: Palliative Care

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    ahsie1
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    The document discusses nausea and vomiting in palliative care, outlining the main sites of activation in the body, the brainstem reflex, and major drug groups used to treat different causes. It notes nausea and vomiting can be triggered by the gastrointestinal tract, chemoreceptor trigger zone, vestibular apparatus, or cerebral cortex, and are managed by targeting specific drug groups at the gastrointestinal system, central nervous system, vestibular system, or chemotherapy/radiation induced causes. Refractory cases may require combining medications, while very refractory cases may need dexamethasone added to the treatment plan.

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    pal care nausea and vomiting

    Original Title

    Nausea and Vomiting

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    The document discusses nausea and vomiting in palliative care, outlining the main sites of activation in the body, the brainstem reflex, and major drug groups used to treat different causes. It notes nausea and vomiting can be triggered by the gastrointestinal tract, chemoreceptor trigger zone, vestibular apparatus, or cerebral cortex, and are managed by targeting specific drug groups at the gastrointestinal system, central nervous system, vestibular system, or chemotherapy/radiation induced causes. Refractory cases may require combining medications, while very refractory cases may need dexamethasone added to the treatment plan.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    14 views10 pages

    Nausea and Vomiting: Palliative Care

    Uploaded by

    ahsie1
    The document discusses nausea and vomiting in palliative care, outlining the main sites of activation in the body, the brainstem reflex, and major drug groups used to treat different causes. It notes nausea and vomiting can be triggered by the gastrointestinal tract, chemoreceptor trigger zone, vestibular apparatus, or cerebral cortex, and are managed by targeting specific drug groups at the gastrointestinal system, central nervous system, vestibular system, or chemotherapy/radiation induced causes. Refractory cases may require combining medications, while very refractory cases may need dexamethasone added to the treatment plan.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 10

    Nausea and Vomiting

    Palliative Care
    Pathway activation

     Main sites of activation


     Gastrointestinal tract
     Chemoreceptor trigger zone
     Vestibular apparatus
     Cerebral cortex

     Brainstem  nausea and vomiting reflex


    ETG groups

     Gastrointestinal

     Central

     Vestibular

     Psychological

     Intracranial

     Chemo/radiotherapy induced
    Major drugs used

     Prokinetic
     Metoclopromide

     Central targeting
     Haloperidol

     Vomit center targeting


     Promethazine or Prochlorperazine
    ETG groups

     Gastrointestinal

     Central

     Vestibular Refractory cases:


    Combine medications
     Psychological

     Intracranial

     Chemo/radiotherapy induced
    ETG groups

     Gastrointestinal

     Central

     Vestibular Very refractory cases:


    + Dexamethasone
     Psychological

     Intracranial

     Chemo/radiotherapy induced
    Points to convey

     Multiple potential causes


     Activation of the protective bodily mechanism to eliminate
    toxins

     Assessment
     Multifactorial  ? Malignant bowel obstruction

     Management goals
     Manage underlying cause
     Reduce symptoms
     Restore appetite

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