of awareness of self and the environment, implying arousal in the brain and perceptual processing of an experience Kesadaran Arousal: determinasi dari fungsi RAS melalui komunikasi neuron antara kortek dan talamus
Cognition/awareness: fungsi simultan dari
dua hemisfer dan keadaan RAS yang intact Sleep Sleep is a regularly occurring state of inactivity during which consciousness is lost and responses to external stimuli are reduced Kesadaran akan hilang dalam kondisi tidur dan koma, dengan kondisi yang berbeda. Saat tidur, otak tetap aktif dan uptake oksigen sama dengan saat sadar. Tidur ada dua fase: 1. NREM: thalamocortical cells are inhibted resulting in reduced cortical stimulation 2. REM: cerebral cortex is highly active, almost identically to that of an awake state, but the peri-locus ceruleus sup- presses muscle tone (atonia), preventing the body from reacting to such cortical activity Suprachiasmatic Nucleus The suprachiasmatic nucleus is the timekeeper of consciousness, maintaining wakefulness and sleep cycles. It is stimulated by light on the retina being transmitted to the hypothalamus Consciousness Area
Sensory input from multiple pathways is channelled
through the reticular formation and onwards to the thalamus and cerebral cortex Neural Pathways in Control Consciousness ASSESSMENT OF CONSCIOUSNESS
Five keys assessing neurologic system:
1. Level of consciousness/LOC (arousal and cognition) 2. Pupil reaction
3. Motor function
4. Sensory function
5. Vital signs AVPU
Popular in recent years as a rapid
assessment of LOC It inadequate for patient with neurologic condition Its difficult for nurse to extent the alteration of consciousness Glasgow Coma Scale (GCS)
The gold standard for assessment of
consciousness throughout the world is the Glasgow Coma Scale (GCS) The GCS was first developed as a 14 point objective scale, then adapted into a 15 point scale, with the addition of ‘abnormal flexion’ to the motor response category High accuracy in assess of LOC Interpretation of GCS Score what you see, always document the patient’s actual response. The lower of GCS means the lower of LOC GCS of 8 or below, with no eye opening is in a coma Head injury: 13-15 (mild), 9-12 (moderate), 3-8 (severe) Has role play in decision at time of resuscitation: GCS 3/15 with fixed dilated pupils indicates that the patient has no realistic chance of survival, whereas GCS 3/15 without fixed dilated pupils is an indicator for aggressive resuscitation GCS also effective in allocating triage priority in emergency care situations ALTERED STATES OF Etiology CONSCIOUSNESS ALTERED STATES OF CONSCIOUSNESS Coma Persistent/permanent vegetative state Minimally conscious state (MCS) Locked-in syndrome Cataplexy and sleep states COMA Coma is an altered state of consciousness characterised by absence of arousal or conscious awareness. Sleep-wake cycles are absent Must last for more than one hour before the term coma is applied. Outcome from coma is related to the cause, and is independent of the patient’s initial presentation, length of time in the coma, or ‘depth’ of the coma Prognosis of Coma Persistent vegetative state (PVS) Persistent vegetative state (PVS) is a chronic neurological syndrome that is characterised by preserved wakefulness, but voluntary interaction with the environment is absent, and there is complete loss of all cognitive functioning. ’Persistent’ refers to the vegetative state continuing for at least one month, but this does not necessarily imply permanency or irreversibility Permanent vegetative : PVS longer than 6 months considered to be irreversible Persistent Vegetative State (PVS) Minimally conscious state (MCS)
10 times more common than PVS
An individual who is in a MCS has a limited, but definite, awareness of themselves or environment, distinguishing this state of consciousness from a vegetative one Minimally conscious state (MCS) Locked-in syndrome Locked-in syndrome (pseudo-coma) is characterised by quadriplegia and anarthria (partial or total loss of motor speech control) and is commonly caused by ventral pontine and brain stem lesions. Awareness of the environment is present, as is sustained eye opening, aphonia or hypophonia and vertical or lateral eye movement. Blinking responses are also present, with eye movement being the only method of communication, as patients have no limb movements or facial expressions. Communication can be difficult as the patient can become exhausted trying to communicate by eye movements alone. Locked-in syndrome Cataplexy and sleep states Cataplexy is a phenomenon that occurs when REM sleep atonia (loss of muscle tone) intrudes into a state of wakefulness, thereby affecting consciousness. No loss of awareness, but unable to respond to the environment due to the loss of motor tone Triggered by strong emotion: sadness, anger, laughter Example: somnambulism (sleep walking), sleep paralysis BRAIN STEM DEATH
Brain stem death results from:
1. Raised intracranial pressure leading to tonsillar herniation 2. Subsequent cerebrocirculatory arrest.
3. Isolated injury to the brain stem, such
as brain stem stroke/infarction. Brain stem death is accepted as death in individual Death is defined as ‘the irreversible loss of the capacity for consciousness, combined with the irreversible loss of the capacity to breathe’ Death occurs when disorders are irreversible, when treatment no longer effective. Assessment of brain stem death NURSING MANAGEMENT OF A PATIENT WITH ALTERED CONSCIOUSNESS
Immediate priorities in the patient who becomes
unconscious 1. Assess A (airway), B (breathing), C (circulation), D (disability), E (exposure) 2. Determine the nursing care required : Maintenance airway Support of breathing (either through artificial ventilation or other respiratory support) Support cardiovascular Evaluation of the extent of neurological compromise Assessment as to the cause of the loss of consciousness Preventing complications of bed rest 1. Pressure area care
High risk of pressure area: male, older, unconscious
and post operative, low BMI, low albumin Assess with tool to determine risk of pressure ulcer (ex: Braden scale) Intervention: turning position, use of pressure relieving mattresses, management of continence and optimisation of nutrition and hydration. EBN: turning position every 4 hr + low-pressure foam based mattresses are better than turning position every 2 hr +standard hospital mattress 2. Deep Vein Thrombosis (DVT) Phrophylaxis Etiology DVT: Hypercoagulability (systemic or local), Venous stasis from poor venous return, and Injury to the venous intima (specifically the endothelium) Virchow Triad See the guideline for prevent DVT (see the box) Passive limb movements : can help venous return to the heart, while also helping to prevent contractures and muscular atrophy 3. Bladder and bowel care Nursing care: Bladder care: catheter in early stage for patient with urinary incontinence, late stage: urinary sheaths or incontinence pads Bowel care: patients are greater risk for constipation fibre enteral feed, adequate hydration, use of laxatives as appropriate and accurate assessment and documentation of bowel function 4. Oral, aural and nasal hygiene Debris can build up around the oral cavity in the unconscious patient, which can be exacerbated by unhumidified oxygen therapy increase oral flora that build up dental plaque Poor oral hygiene has also been associated with ventilator acquired pneumonia (VAP) due to build up of bacteria within plaque. Nursing intervention: For unconscious patients, oral hygiene with a toothbrush and toothpaste or water twice daily should suffice, and for ventilated patients additional using antiseptics such as chlorhexidine is recommended for this patient group Nasal mucosa and exter- nal aural canals may also require cleansing to remove debris. 5. Eye care Unconscious patients will not have a protective blink reflex, and the tears required to cleanse and hydrate the eyes will not be spread over the surface of the cornea. Eyelid closure is also often incomplete. Risk of corneal dehydration, keratitis, abrasions and in extreme cases ulceration, perforation, scarring and possibly permanent visual impairment Nursing intervention: Cleanse of closed eyes with normal saline and gauze
Maintain hydration through prescribed lubricating drops,
ointments, or polyethylene covers Keep the eye lids remain closed to prevent keratitis and epithelial erosion 6. Communication needs of patients and family Verbal communication and interaction received by the unconscious patient is less than that received by patients who are verbally responsive Communication needs to extend to the family members who will often be experiencing a traumatic situation. The need for family centred care that emphasises better communication and involvement of family in the process of care throughout 7. Psychological support for the patient’s family Symptoms of depression and anxiety linked with thoughts of the possible death of the patient often occurs in family Nurses are ideally placed to offer support to families, listen to their concerns and explain everything that is happening. Relatives may feel helpless and can appreciate opportunities to become involved in patient care, but equally may be reluctant to get involved and so should not be put under pressure to participate. NURSING MANAGEMENT OF A PATIENT WITH BRAIN STEM DEATH A patient who has been diagnosed with brain stem death may still exhibit spinal reflex responses (example: periodic leg movement) misinterpretation consider patient is alive. It is crucial for nurses to be proactive in assisting relatives to understand the concept of brain stem death This has the potential to increase consent for organ donation, but more importantly may help the family in grieving for their loved one. Brain stem death with a GCS of 7 or less are identified as having potential to be eventual organ donors REFERENCES Woodward, S.W., Mestecky,A.M.2011. Neuroscience Nursing Evidence Based Practice. United Kingdom: Wiley-Blackwell Wilkinson,I ., Lennox, G. 2005. Essential Neurology (4 th edition). Oxford : Blackwell Publishing . Azoulay E, Pochard F (2003) Communication with family members of patients dying in the intensive care unit. Current Opinion in Critical Care 9(6): 545– 550.