OBAT PSIKOTROPIK =PSIKOTROPIKA

=PSIKOFARMAKA
Adalah obat yang bekerja secara
selektif pada susunan saraf pusat
(SSP)dan mempunyai efek utama
terhadap aktivitas mental dan prilakun
(mind and behavior altering drugs),
digunakan untuk terapi gangguan
psikiatrik (psychotherapeutic
medication).
Orientasi pada gejala sasaran
(target syndrome oriented)
JENIS OBAT GEJALA SASARAN

Anti – psikosis Psikosis

Anti – depresi Depresi
Anti – mania Mania
Anti – anxietas Anxietas
Anti – insomnia Insomnia
Anti – obsesif kompulsif Obsesif kompulsif
Anti – panik Panik
 WHO-REVISED LIST OF
ESSENTIAL DRUGS 1994
Section 24. Psychotherapeutic Drugs Obat Psikotropik
24.1. Drugs used in psychotic Anti - Psikotic
disordes
24.2. Drugs used in mood Anti-depresi
disorders Anti-mania
24.3. Drugs used in obsessive Anti-anxietas
and generalised anxiety Anti-insomnia
disorders
24.4. Drugs used in
Butir-butir yang harus selalu di-ingat dalam
penggunaan klinis obat psikotripika

• Sesuai dengan situasi dan kondisi

individual (tailored)
• Penyesuaian secara bertahap (stepwise)
• Pantau terus menerus (monitoring)
• Terencana dan terprogram (rational
management)
I.OBAT-OBATA ANTI PSIKOSIS
NEUROLEPTICS, MAJOR
TRANQUILLIZERS
ANTARICTICS,
ANTIPSYCHOTICS,
ANTIPSYCHOTIC DRUGS,
NEUROLEPTIKA
II. OBAT ANTI-PSIKOSIS TIPICAL

(TYPICAL ANTI PSYCHOTICS)

1. Phenotiazine
* rantai Aliphatic : chlorpromazine (largactil)
* rantai Piperazine : perphenazine (stelazine)
trifluoperazine (antensol)
* rantai Piperidine : thioridazine (melleril)
2. Butyrophenone : haloperidol (haldol,
serenace,dll)
3. Diphenyl-butyl - : pimozide (Orap)
piperidine
III. Obat anti-psikosis atipikal
(atypical anti psychotics)
1. Benzamide : Sulpiride (Dogmatil)
2. Dibenzodiazepine : Clonzapine (Clozaril)
Olanzapine (Zyprexal)
Quetiapine (Seroquel)
Zatepine (Lodopin)
3. Benzisoxazole : irsperidon (Risperdal)
Aripiprazole (Abilify)
OBAT ANTI DEPRESI
1. THYMOLEPTICS,
PSYCHIC ENERGIZERS,
ANTI DEPTRESSANTS,
ANTIDEPRESAN
1. Tricyclic Compound
2. Tetracyclic Compound
3. Mono-Amine-Oxydase
Inhibitor (MAO)-Reversible
4. Selective Serotonin
Re-uptake Inhibitors (SSRI)
5. Atypical Antidepresants
: Amitriptyline (Amitriptyline)
IMIPRAMINE (Tofrnil)
Clomipramine (Anafranil)
Tianeptine (Stablon)
: Maprotinile (Ludionil)
Mianseri (Tolvon)
Amoxapine (Asendin)
: Moclobemide (Aurorix)
: Sertraline (Zoloft)
Paroxetine (Seroxat)
Fluvoxamine (Luvox)
Fluoxetine (Prozac)
Citalopram (Cipram)
Duloxetine (Cymbalta)
: Trazodone (Trazone)
Mirtazapine (Remoron)
Venlafaxine ( Efexor)
 OBAT ANTI MANIA
MOOD MODULATORS, MOOD
STABILIZERS, ANTIMANICS

• Mania Akut : Haloperidol (haldol, serenace, dll)

Carbamazepine (Tegretol) ;
Vaproic (Depakene); Diivalproex
(Depakote)
• Profilaksis
Mania : Lithium Carbonate (Frimania)
 OBAT ANTI ANXIETAS
Psycholeptics, minor trnquillizers anxiolytics,
antianxiety drugs, ansiolitika
1. Benzodiazepine
Diazepam (Valium,Stesolit,dll)
Chlordiazepoxide (Cetabrium, dll)
Bromazepam (Lexotan)
Lorazepam (Ativan, Renaquil, Merlopan)
Alprazolam (Xanax, Alqanax, Calmlet,dll)
Clobazam (Frisium, dll)
2. Non-Benzodiazepine
Buspirone (Buspar, Tran-Q, Xiety)
Sulpiride (Dogmatil-50)
Hydroxyzine (Iterax)
 OBAT ANTI INSOMNIA
HYPNOTICS, SOMNIFACIENT, HIPNOTIKA

1. BENZODIAZEPINE
Nitrazepam ( Dumolid )
Flurazepam ( Dalmadorm )
Estazolam ( Esilgan )

2. NON-BENZODIAZEPINE
Zolpidem ( 0Stilnox,Zolmia )
1. Obat Anti-Obsesif Kompulsif Trisiklik
Clompramine (Anafranil)
2. Obat anti Obsesif Kompulsif
Setraline (Zolaft)
Paroxetine (Seroxat)
Fluvoxamine (Luvox)
Fluoxetine (Prozac)
Citalopram (Cipram)
 OBAT ANTI-PANIK
DRUGS USED IN PANIC DISORDER
1. Obat anti panik TRISIKLIK
Imipramine (Tofrani)
Clomipramine (Anafrani)
2. Obat anti-panik BENZODIAZEPINE
Alprazolam (Xanaz, Alqanax,Calmlet, dll)
3. Obat anti-panik RIMA
(Reversible Inhibitors of Monoamine oxydase-A)
Moclobemide (Aurorix)
4. Obat anti-panik SSRI
Sertralne (Zoloft)
Paroxetine (Seroxat)
Fluvoxetine (Luvox)
Fluoxetine (Prazac)
Citalopram (Cipram)