NON-TOXIC GOITER

NADIFA KARTIKA DEWI

1510211074
• DEFINITION : hypothyroid that result from inadequate tyroid
hormone synthesis
• ETIOLOGY
• EPIDEMIOLOGI :
terjadi secara endemik pada beberapa negaa seperti africa, area
pegunungan di asia tengah, Andes, bagian tengah eropa dan
Indonesia

• Goiter may occur endemically (prevalence in children ≥5%), due

mainly to iodine deficiency, or sporadically (prevalence <5%). In the
general population, the Framingham survey indicated a 4.6%
overall prevalence (6.4% in women and 1.5% in men)
 CLINICAL FEATURES
• SIGN AND SYMPTOMS
– (usually) Thyroid enlargement
– Gland may be firm or rubbery consistency
– Gland may become progressively larger
– Facial flushing and dilatation of cervical vein
– Pembertn sign
• LAB FINDINGS
– Normal FT4, normal level of TSH
• IMAGING STUDIES
MANAGEMENT
 TREATMENT
• management of nontoxic goiters consists simply of
observation, without any specific therapy.
• Nontoxic goiters are very slow growing and usually never cause
compressive symptoms or thyroid dysfunction
• Surgery is indicated for goiters that continue to grow or that
produce obstructive symptoms
• If the patient is not a suitable candidate for surgery,
radioiodine ablation of functioning thyroid tissue may provide
palliative relief of obstructive symptoms. An adequate dose of
radioiodine reduces the size of the goiter about 30– 50% and
usually alleviates obstructive symptoms.