CHEMISTRY How it affects Cardiovascular Disease HDL’S http://www.youtube.com/watch?v=wnK1Kv3XkZI
HDL= lipoproteins, which are combinations of
lipids and proteins.
HDL is considered the “good cholesterol”.
Higher levels of HDL’s reduce risk of heart
disease
Healthy lifestyle changes can increase HDL
levels. LDL’S LDL= low density lipoprotein…..BAD cholesterol LDL’s carry the cholesterol throughout the body for use by different cells, but if there is too much cholesterol it can build up on artery walls Plaque build up= blocked arteries= heart attacks and strokes Under 100 mg/dL = good level
Age & Tests, diet, exercise, weight loss,
medications WHAT ARE TRIGLYCERIDES? • the chemical form in which most fat exists in food as well as in the body • present in blood plasma and, in association with cholesterol, form the plasma lipids • Triglycerides in plasma are derived from fats eaten in foods or made in the body from other energy sources like carbohydrates. • Hormones regulate the release of triglycerides from fat tissue so they meet the body's needs for energy between meals. HOW DO TRIGLYCERIDES CONTRIBUTE TO HEART DISEASE? • High triglycerides increased the risk of heart attack 3-fold • High triglyceride levels are associated with risk factors for heart disease: low levels of HDL, high levels of LDL • Hypertriglyceridemia= abnormal concentration of triglyceride in blood. • Hypertriglyceridemia can lead to Atherosclerosis , where deposits build up in the inner lining of an artery, leading to the hardening of arteries. WHAT IS A HEALTHY AMOUNT?
*These are based on fasting plasma
triglyceride levels. MAINTAINING NORMAL LEVELS… • Lose excess pounds. • Cut back on calories. • Avoid sugary and refined foods. • Limit the cholesterol in your diet. • Choose healthier fats. • Eliminate trans fat. • Avoid alcoholic beverages. • Exercise Regularly. GLUCOSE Diabetics are twice more likely to get heart disease than non-diabetics
People with diabetes also tend to get heart
disease at an earlier age
High blood glucose levels damage nerves and
blood vessels BLOOD PRESSURE High blood pressure killed 49,707 Americans in a year High blood pressure increases risk for heart disease and stroke, both leading causes of death in U.S. Among people with high blood pressure 31.6% are unaware they have it High blood pressure is easily detectable and usually controlled by life modifications: exercise, diet BLOOD CLOTS Atherosclerosis
Starts when platelets
clump together around plaque
Plaque forms when
cholesterol & other substances build up in inner lining of arteries