Farmakokinetik

Pola kadar obat

dalam darah pada
berbagai 
Bagaimana jika dosis
terlewatkan?
Regimentasi dosis –
pola kadar obat
dalam darah
Apa yang terjadi jika
ada perubahan
parameter
Fkinetika?
Drug plasma level
 Possible intervening steps between
Type of administration and appearance of drug
Dosage form in solution in gastrointestinal fluids
Aqueous
solution
Precipitation

Suspension of Solution of
Dissolution Absorption
Aqueous fine particles of drug in
suspension drug in gastrointestinal Blood
gastrointestinal fluids
fluids
Deaggregation

Desintegration
Immediate Dissolution
Aggregate
release solid or
dosage form granules
 Pharmacokinetic model

Drug in Drug in OUTPUT Drug

INPUT Drug in body
dosage solution in in
compartement
form GIT fluids urine

One-compartement model of drug disposition for a perorally administered drug