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Abirapro 500mg
Abirapro 500mg
Abirapro 500mg
Abirapro 500mg tablet is exist to type of
anti-cancer drug that will execution by
slump the androgen production in the
body. Androgen is a male hormone that
can provide the tumor cell in prostate
glands. This drug is given by co organization
with prednisolone, a steroid which
decrease the burden of side effects
produced by Abirapro.
Androgens are harmony the production
of diseased in prostate.
Abirapro 500mg exist to anti androgen
drugs, that purpose to contain the
enzyme 17α-hydroxylase C 17, 20-lyase
(CYP17), it is including in androgen
conglomerate.
Decrease the serum testosterone level.
Refuse the tumor cell occurred.
Absorption: Time to maximum plasma combination
of Abirapro 500mg takes 12 hours.
Distribution: Maximum bound to the human plasma
protein like albumin and alpha-1 acid glycoprotein.
Metabolism: The main two metabolites of Abirapro
500mg tablet in human plasma are Abiraterone
sulphate and N-oxide Abiraterone sulphate.
Excretion: The drug mainly excreted in 88% feces and
5% in urine
Half-life of tablet Abirapro 500mg is 12 ± 5 hours.
Common effects
Fatigue, Arthralgia, Hypertension, Nausea,
edema, Hypokalemia, Diarrhea, vomiting,
Cough, headache, Glucocorticoid
deficiency, Mineral corticoid deficiency,
Hepatotoxicity, Hypertension, Decrease in
ka level, Adrenocortical insufficiency
Muscular skeletal and Connective tissue
disorders: Joint swelling, discomfort, muscle
discomfort
General Disorder: Edema
The prescribed dose of Abirapro 500mg is initial
as 4 tablets given orally once daily.
The drug Abirapro 500mg execute sequence
with 5mg prednisolone twice daily in vacant
stomach.
Abirapro 500mg tablet given on avacant
stomach.
Food should not be taken for at least 2 hours
before and at least 1 hour after the dose of
Abirapro 500mg is taken.
Consume whole with water.
Chomp the tablets or Do not crush
Cooperation Abirapro 500mg with strong
CYP3A inhibitors or inducers, concomitant
use with prudence because
pharmacokinetics is not estimated.
cooperation of Abirapro 500mg tablet with
dextromethorphan will accession the
Cmax and AUC of dextromethorphan
SAFETY AND WARNING OF Abirapro 500mg
Any allergy, severe liver problem or
pregnant in patient, Abirapro 500mg tablet
therapy should be interrupted
OVERDOSAGE
Abirapro 500mg has no vital antidote, if
overdose develop end treatment with the
drug and give general supportive measures
such as monitoring arrhythmias and cardiac
failure and assess liver function.
MISSED DOSE
If patient missed the dose of Abirapro
500mg tablet , that missed dose will be
skipped and follow the regular dosing
schedule.
PREGNANCY
Pregnancy category X: while on therapy
with Abirapro 500mg if women become
pregnant, immediately stop the drug and
give counseling to the women. Abirapro
500mg tablet is not recommended for
women.
LACTATION
Abirapro 500mg not used in women
excretion in human milk is unknown and the
drug effects in the nursing infant is
unknown.
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500mg