VALIDITY Study Population:

Children hospitalized with

Study design: severe cutaneous reaction.
Retrospective cohort study Patient were younger than 18
years at the time of admission.
Inpatient or observation

Study site: Study subjects:

47 US Freestanding children’s 898 patient include in
hospital inclusion and exlusion criteria.

Study time: Data analyses:

Between January 1, 2008 and 1. Pearson chi-square
December 31, 2015 2. Mann-whitney test
3. Multivariable linear regression
models
4. Multivariable logistic model

Software: SAS version 9.4statistical

 INCLUSION AND EXCLUSION CRITERIA
INCLUSION CRITERIA EXCLUSION CRITERIA

1. Chlidren hospitalized with severe 1. Subject had a concurrent diagnosis of

cutaneous reaction disease associated with cutaneous
2. Age <18 years old at the time of reaction
admission
3. Inpation or observation patient
 IMPORTANCY

This journal provide evidence of the management strategies

used in children with SJS and TEN, also determine clinical
outcome such as length of stay, mortality, ruccurence and
complication.