OXYGEN THERAPY

Oxygen Delivery (Do2)

• There are six steps of oxygen delivery
1. Ventilation  convection oxygen from environment into the body
2. Oxygen uptake  diffusion oxygen into the blood
3. Reversible chemical bonding with haemoglobin
4. CO: cardiac output convective transport oxygen into tissue
5. Diffusion into cells and organelle to mitochondria
6. The redox state of the cells
Pathology of Oxygen Delivery - Type of Hypoxiae
Variable-Performance system
Fixed Performance
System
Fixed Performance
System
Hazzard Oxygen Therapy
• Supply
 barotrauma to the airway and alveolus related to oxygen pressure
 Risk of explosion while using nasal cannula due to smoking or
defibrillating
• Oxygen toxicity 
• Central nervous system toxicity
(paul bert effect)
• Lung toxicity (lorriane smith effect)
• Bronchopneumonia dysplasia
• Retinopathy of prematurity (ROP)
Hyperbaric
Oxygen
Therapy
Hyperbaric therapy
complication